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https://www.readbyqxmd.com/read/28641569/a-review-on-defects-of-dendritic-cells-in-common-variable-immunodeficiency
#1
Laleh Sharifi, Naeimeh Tavakolinia, Fatemeh Kiaee, Nima Rezaei, Monireh Mohsenzadegan, Mansoureh Shariat, Reza Yazdani, Abbas Mirshafiey, Asghar Aghamohammadi, Gholamreza Azizi
BACKGROUND AND OBJECTIVES: Common variable immunodeficiency (CVID) is the most important primary that is associated with clinical complications including recurrent infections, malignancy and autoimmune diseases. The genetic cause of CVID is mostly unknown and only a few genetic causes are identified. The various options are proposed for determining the etiology of CVID patients, such as T- and B-cell defects, Toll-like receptors (TLRs) impairments, altered cytokine production as well as blemished dendritic cells (DCs)...
June 13, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/28580223/carotid-cavernous-fistula-with-central-retinal-artery-occlusion-and-terson-syndrome-after-mid-facial-trauma
#2
Satya Karna, Mukesh Jain, Md Shahid Alam, Bipasha Mukherjee, Rajiv Raman
Objectives: To report a rare occurrence combination of central retinal artery occlusion (CRAO) and Terson syndrome in a Barrow's type A carotid cavernous fistula (CCF) patient. Methods: Observational case report. Results: A twenty-year-old male patient with a history of road traffic accident presented with periorbital swelling and redness in the left eye. Examination revealed a CRAO with intraretinal and preretinal hemorrhages. On imaging, type A CCF and subarachnoid hemorrhage were detected. He underwent embolization of the fistula for cosmetic blemish...
2017: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/28387613/sexual-reproduction-in-the-citrus-black-spot-pathogen-phyllosticta-citricarpa
#3
Nga T Tran, Andrew K Miles, Ralf G Dietzgen, Megan M Dewdney, Ke Zhang, Jeffrey A Rollins, André Drenth
Citrus black spot (Phyllosticta citricarpa) causes fruit blemishes and premature fruit drop, resulting in significant economic losses in citrus growing areas with summer rainfall across the globe. The mating type locus of P. citricarpa has recently been characterized, revealing the heterothallic nature of this pathogen. However, insight into the occurrence of mating and the impact of completing the sexual cycle of P. citricarpa was lacking. To investigate the occurrence and impact of sexual reproduction, we developed a method to reliably, and for the first time, produce ascospores of P...
June 2017: Phytopathology
https://www.readbyqxmd.com/read/28241731/the-q-cycle-mechanism-of-the-bc1-complex-a-biologist-s-perspective-on-atomistic-studies
#4
Antony R Crofts, Stuart W Rose, Rodney L Burton, Amit V Desai, Paul J A Kenis, Sergei A Dikanov
The Q-cycle mechanism of the bc1 complex is now well enough understood to allow application of advanced computational approaches to the study of atomistic processes. In addition to the main features of the mechanism, these include control and gating of the bifurcated reaction at the Qo-site, through which generation of damaging reactive oxygen species is minimized. We report a new molecular dynamics model of the Rhodobacter sphaeroides bc1 complex implemented in a native membrane, and constructed so as to eliminate blemishes apparent in earlier Rhodobacter models...
April 20, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28107564/tattoo-removal-by-q-switched-yttrium-aluminium-garnet-laser-client-satisfaction
#5
K Hutton Carlsen, J Esmann, J Serup
BACKGROUND: Tattoo removal by Q-switched yttrium aluminium garnet (YAG) lasers is golden standard; however, clients' satisfaction with treatment is little known. OBJECTIVE: To determine clients' satisfaction with tattoo removal. METHODS: One hundred and fifty-four tattoo removal clients who had attended the private clinic 'Centre for Laser Surgery', Hellerup, Denmark, from 2001 to 2013 completed a questionnaire concerning outcome expectations, level of pain experiences and satisfaction with tattoo removal...
May 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27819539/direct-estimation-of-local-ph-change-at-infection-sites-of-fungi-in-potato-tubers
#6
R Tardi-Ovadia, R Linker, L Tsror Lahkim
Fungi can modify the pH in or around the infected site via alkalization or acidification, and pH monitoring may provide valuable information on host-fungus interactions. The objective of the present study was to examine the ability of two fungi, Colletotrichum coccodes and Helminthosporium solani, to modify the pH of potato tubers during artificial inoculation in situ. Both fungi cause blemishes on potato tubers, which downgrades tuber quality and yield. Direct visualization and estimation of pH changes near the inoculation area were achieved using pH indicators and image analysis...
January 2017: Phytopathology
https://www.readbyqxmd.com/read/27802631/resisting-and-pinning-of-a-nanodrop-by-trenches-on-a-hysteresis-free-surface
#7
Cheng-Chung Chang, Cyuan-Jhang Wu, Yu-Jane Sheng, Heng-Kwong Tsao
The encounter of a nanodrop with a trench on a hysteresis-free surface is explored by many-body dissipative particle dynamics to show the effect of surface roughness on droplet wetting. A free nanodrop exhibits Brownian motion and the diffusivity decays exponentially with the liquid-solid contact area. In contrast, as the nanodrop sits on a trench, its random motion is constrained. Work must be done to overcome the energy barriers for the transition between free and trapped states. The potential energy landscape is thus constructed based on the force-displacement plot...
October 28, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/27658746/site-of-pgf2%C3%AE-injection-does-not-alter-effectiveness-of-the-select-synch-controlled-internal-drug-release-and-timed-artificial-insemination-protocol
#8
RANDOMIZED CONTROLLED TRIAL
C L Pickworth, L M Bell, W Greene, C S Whisnant, D H Poole
Beef Quality Assurance programs have contributed to significant improvements in the wholesomeness of beef available for consumption. Injection site blemishes in the round have declined since the promotion of administering intramuscular injections in the neck. Unfortunately, many producers continue to administer estrus synchronization (ES) drugs in the rump. The objective of this study was to compare the effectiveness of injection site of PGF2α, in ES protocols, on steroid hormone concentrations and pregnancy rates...
January 1, 2017: Theriogenology
https://www.readbyqxmd.com/read/27651516/the-blemishes-of-modern-society-acne-prevalence-in-the-dogon-of-mali
#9
Christine E Campbell, Beverly I Strassmann
BACKGROUND AND OBJECTIVES: Non-communicable diseases may reflect an evolutionary mismatch between our human ancestry and modern environments. To explore the mismatch hypothesis for Acne vulgaris, we studied the prevalence and severity of acne in Dogon adolescents in Mali, West Africa. METHODOLOGY: We graded the prevalence and severity of acne in 1182 Dogon adolescents aged 11-18 years from nine villages using facial photos taken as part of a prospective cohort study...
2016: Evolution, Medicine, and Public Health
https://www.readbyqxmd.com/read/27642795/direct-estimation-of-local-ph-change-at-infection-sites-of-fungi-in-potato-tubers
#10
Rinat Tardi-Ovadia, Raphael Linker, Leah Tsror
Fungi can modify the pH in and/or around the infected site via alkalinization or acidification and pH monitoring may provide valuable information on host-fungus interactions. The objective of the present study was to examine the ability of two fungi, Colletotrichum coccodes and Helminthosporium solani, to modify the pH of potato tuber during artificial inoculation in situ. Both fungi cause blemishes on potato tubers which downgrade tuber quality and yield. Direct visualization and estimation of pH change near the inoculation area were achieved using pH indicators and image analysis...
September 19, 2016: Phytopathology
https://www.readbyqxmd.com/read/27573581/do-nymphs-and-adults-of-three-neotropical-zoophytophagous-mirids-damage-leaves-and-fruits-of-tomato
#11
D B Silva, V H P Bueno, F J Calvo, J C van Lenteren
The predators Macrolophus basicornis (Stal), Engytatus varians (Distant) and Campyloneuropsis infumatus (Carvalho) consume large numbers of tomato pests such as Bemisia tabaci (Gennadius) and Tuta absoluta (Meyrick). However, they are zoophytophagous and feed on plant parts as well. We evaluated the type and effect of injury caused by nymphs and adults of these mirids on tomato seedlings and fruit in the absence of prey. For each mirid species, seedlings were exposed to groups of 20 nymphs or adults for 72 h, and fruits were exposed for 48 h to groups of four nymphs or adults...
April 2017: Bulletin of Entomological Research
https://www.readbyqxmd.com/read/27500406/diminished-kcc2-confounds-synapse-specificity-of-ltp-during-senescence
#12
REVIEW
Isabella Ferando, Guido C Faas, Istvan Mody
The synapse specificity of long-term potentiation (LTP) ensures that no interference arises from inputs irrelevant to the memory to be encoded. In hippocampi of aged (21-28 months) mice, LTP was relayed to unstimulated synapses, blemishing its synapse specificity. Diminished levels of the K(+)/Cl(-) cotransporter KCC2 and a depolarizing GABAA receptor-mediated synaptic component following LTP were the most likely causes for the spreading of potentiation, unveiling mechanisms hindering information storage in the aged brain and identifying KCC2 as a potential target for intervention...
September 2016: Nature Neuroscience
https://www.readbyqxmd.com/read/27431444/people-use-psychological-cues-to-detect-physical-disease-from-faces
#13
Konstantin O Tskhay, John Paul Wilson, Nicholas O Rule
Previous theoretical work has suggested that people can accurately perceive disease from others' appearances and behaviors. However, much of that research has examined diseases with relatively obvious symptoms (e.g., scars, obesity, blemishes, sneezing). Here, we examined whether people similarly detect diseases that do not exhibit such visible physical cues (i.e., sexually transmitted diseases). We found that people could indeed identify individuals infected with sexually transmitted diseases significantly better than chance from photos of their faces...
October 2016: Personality & Social Psychology Bulletin
https://www.readbyqxmd.com/read/27349831/effect-of-lairage-time-behaviour-and-gender-on-stress-and-meat-quality-parameters-in-pigs
#14
Marija Dokmanovic, Jelena Ivanovic, Jelena Janjic, Marija Boskovic, Milica Laudanovic, Srdjan Pantic, Milan Z Baltic
The objective of this study was to determine the effects of lairage time (short vs. long), behavior (aggressive vs. non-aggressive) and gender (gilts, barrows and boars) on stress and meat quality parameters in pigs (n = 100). In the group with short lairage, aggressive behavior of gilts and boars was observed. At exsanguination, blood samples were collected and levels of blood lactate and plasma cortisol were determined. Post mortem pH value, temperature, drip loss, sensory and instrumental color and meat quality class were determined on the muscle Longissimus dorsi...
March 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/26964666/peltaster-fructicola-genome-reveals-evolution-from-an-invasive-phytopathogen-to-an-ectophytic-parasite
#15
Chao Xu, Huan Chen, Mark L Gleason, Jin-Rong Xu, Huiquan Liu, Rong Zhang, Guangyu Sun
Sooty blotch and flyspeck (SBFS) fungi are unconventional plant pathogens that cause economic losses by blemishing the surface appearance of infected fruit. Here, we introduce the 18.14-Mb genome of Peltaster fructicola, one of the most prevalent SBFS species on apple. This undersized assembly contains only 8,334 predicted protein-coding genes and a very small repertoire of repetitive elements. Phylogenomics and comparative genomics revealed that P. fructicola had undergone a reductive evolution, during which the numbers of orphan genes and genes involved in plant cell wall degradation, secondary metabolism, and secreted peptidases and effectors were drastically reduced...
March 11, 2016: Scientific Reports
https://www.readbyqxmd.com/read/26645515/the-effect-of-moxibustion-on-alleviating-menstrual-pain-in-a-population-of-young-nursing-students-a-prospective-randomized-cross-over-pilot-study
#16
RANDOMIZED CONTROLLED TRIAL
Jing Gao, Qi Wang, Shaoxiang Xian, Yue-mei Feng, Wei-xin Cao, Jing-yun Ye, Qing-qing Zhang, Cai-lian Zou, Qing-guang Wu, Si-jun Liu
OBJECTIVE: To investigate the effect of moxibustion on alleviating menstrual pain and relieving the symptoms of dysmenorrhea in a cohort of young nursing students in China. METHODS: A randomized double blind clinical trial of crossover design was used. In the two-phase study, a total of 56 nursing students with menstrual pain in Guangzhou University of Chinese Medicine in China was randomly allocated into two groups. In the first treatment phase, the participants in Group A (n=28) received moxibustion therapy from five days before the menstrual period to the onset through a specific heating box in which burning moxa stick was fixed, the participants in Group B (n=28) received the same heating box but with a paper-wrapped stick incense fixed inside (placebo therapy) during the same intervention period...
December 2015: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/26541705/-cutaneous-mastocytosis-a-case-report
#17
María Soledad Zegpi-Trueba, Paula Hasbún-Acuña, Daniela Berroeta-Mauriziano
INTRODUCTION: Mastocytosis represents a group of diseases characterised by an excesive accumulation of mastocytes in one or multiple tissues. It can affect only the skin, or have a systemic involvement. It has a low prevalence, and the prognosis is benign in children. OBJECTIVE: To report a case of urticaria pigmentosa as a subtype of cutaneous mastocytosis, and present a literature review focused on clinical findings, diagnosis and initial basic management. CLINICAL CASE: A child of six months of age presenting with multiple blemishes and light brown papules located on the trunk, arms and legs...
May 2016: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/26350872/stigmatised-patients
#18
COMMENT
Rose Gallacher
Individuals at increased risk of stigmatisation include those with particular physical traits or perceived character 'blemishes'.
September 9, 2015: Nursing Standard
https://www.readbyqxmd.com/read/26349968/foxq1-promotes-esophageal-cancer-proliferation-and-metastasis-by-negatively-modulating-cdh1
#19
Yangqing Pei, Pan Wang, Hongchun Liu, Fucheng He, Liang Ming
BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is an aggressive tumor with rapid progression, high recurrence and metastasis rate. Besides, the 5-year survival rate of ESCC remains dismal despite improvements in treatments having developed a lot. That is because the cellular basis of ESCC has not yet been fully understood. Forkhead box family membranes possess various kinds of properties as they mediate apoptosis, cell cycle arrest, autophagy, senescence and so on. Foxhead box Q1 (FOXQ1), which has a major impact on several kinds of tumor forming and metastasis, while whether it triggers ESCC remains largely obscure...
August 2015: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/26275739/adult-sacrococcygeal-teratoma-the-third-leg-a-rare-case-report-in-a-25-year-old-man
#20
M S Kiran Kumar Yekula, Anudeep Yekula
INTRODUCTION: Sacrococcygeal Teratoma (SCT) is a rare benign neoplasm comprised of mixed elements derived from two or more germ cell layers. They are extremely rare in adults. They attract attention because of their gross appearance and bizarre histology. PRESENTATION OF CASE: A 25 year old male presented to Surgical OPD, Government General Hospital, Guntur Medical College, Guntur with a large mass comprising a partially developed 3rd leg and rudimentary external genitalia in the lower back...
2015: International Journal of Surgery Case Reports
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