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https://www.readbyqxmd.com/read/28800901/dentifrices-specifically-formulated-for-tooth-whitening-reduce-extrinsic-tooth-surface-discoloration
#1
Tahira Devji
No abstract text is available yet for this article.
August 6, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28796288/a-novel-topical-agent-in-the-treatment-of-seborrheic-keratoses-a-proof-of-concept-study-by-clinical-and-dermoscopic-evaluation
#2
Francesco Lacarrubba, Maria Rita Nasca, Anna Elisa Verzì, Giuseppe Micali
In this proof of concept study, 50 lesions from 15 patients with multiple seborrheic keratoses (SKs) were treated with a novel aqueous solution containing nitric acid, zinc and copper salts, and organic acids (acetic, lactic, and oxalic acid). Treatment consisted in the application of an amount of the solution sufficient to obtain a whitening/yellowish reaction. Application of the nitric-zinc solution was performed every other week until clinical and dermoscopic clearance or crust formation, for a maximum of 4 applications...
August 10, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28793915/the-functional-property-of-royal-jelly-10-hydroxy-2-decenoic-acid-as-a-melanogenesis-inhibitor
#3
Chi-Chung Peng, Hui-Tzu Sun, I-Ping Lin, Ping-Chung Kuo, Jen-Chieh Li
BACKGROUND: It has been reported that royal jelly would reduce melanin synthesis and inhibit the expression of melanogensis related proteins and genes. In this study, we evaluate the anti-melanogenic and depigmenting activity of 10-hydroxy-2-decenoic acid (10-HDA) from royal jelly of Apis mellifera. METHODS: In this study, we assesses the 10-HDA whitening activity in comparison with the changes in the intracellular tyrosinase activity, melanin content and melanin production related protein levles in B16F1 melanoma cells after treating with 10-HDA...
August 9, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28790335/involvement-of-transient-receptor-potential-cation-channel-member-a1-activation-in-the-irritation-and-pain-response-elicited-by-skin-lightening-reagent-hydroquinone
#4
Yan Tai, Chuan Wang, Zhihua Wang, Yi Liang, Junying Du, Dongwei He, Xiaoyan Fan, Sven-Eric Jordt, Boyi Liu
Hydroquinone (HQ) is one of the most frequently used and effective skin-lightening products to treat skin hyperpigmentation disorders, including postinflammatory hyperpigmentation, melasma and solar lentigines. HQ is also widely used in cosmetic products for skin whitening. However, HQ treatment can evoke substantial skin irritation, a side effect that remains poorly understood. Here we demonstrate that HQ is an activator of the peripheral irritant receptor transient receptor potential (TRP) cation channel member A1 (TRPA1)...
August 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28766970/effect-of-polyphenols-from-vicia-faba-l-on-lipase-activity-and-melanogenesis
#5
Ahmed E Allam, Alaa M Nafady, Toshinori Nakagawa, Naomichi Takemoto, Kuniyoshi Shimizu
Two new flavonoid glycosides, kaempferol 3-O-α-L-rhamnopyranosyl (1→6) (3''-acetyl)-β-D-galactopyranoside 1 and kaempferol 3-O-α-L-arabinopyranosyl-5-O-α-L-rhamnopyranoside 2, along with six known ones 3-8 were isolated from the flowers of Vicia faba L. (Fabaceae). Methanol extract and the isolated compounds were tested against lipase and melanogenesis inhibition activities and resulted in that compound 2 showed 53 and 77% lipase inhibition activity in concentrations of 400 and 800 μg/mL, respectively...
August 2, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28765043/feruloylserotonin-inhibits-hydrogen-peroxide-induced-melanogenesis-and-apoptosis-in-b16f10-and-sk-mel-2-melanoma-cells
#6
Hyejoung Cho, Okjoon Kim, Younghee Lee, Li-Jung Kang, Cam Ngoc Nguyen, Atsushi Ishihara, Hye-Eun Kim
Feruloylserotonin (FS) is a major bioactive component of safflower seeds, with documented strong antibacterial, anti-inflammatory, and free radical scavenging activities. Reactive oxygen species (ROS) can strongly induce melanogenesis and cell apoptosis. The present study aimed to investigate the ability of FS in preventing hydrogen peroxide (H2O2)-induced melanogenesis and cell apoptosis. Melanogenesis and apoptotic cell death were induced by transient exposure to H2O2 in B16F10 and SK-Mel-2 melanoma cells...
July 29, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28762524/resilience-of-experimentally-seeded-dietary-traditions-in-wild-vervets-evidence-from-group-fissions
#7
Erica van de Waal, Carel P van Schaik, Andrew Whiten
Controlled laboratory experiments have delivered extensive and compelling evidence for the diffusion and maintenance of socially learned behavior in primates and other animals. Such evidence is rarer in the wild, but we show that a behavior seeded in a majority of individuals within vervet monkey (Chlorocebus pygerythus) groups may be sustained across several years. Here, we report results of two natural fission events in such groups that offer novel evidence of the resilience of socially transmitted group norms of behavior...
August 1, 2017: American Journal of Primatology
https://www.readbyqxmd.com/read/28754032/spectrum-effect-relationship-and-component-knock-out-in-angelica-dahurica-radix-by-high-performance-liquid-chromatography-q-exactive-hybrid-quadrupole-orbitrap-mass-spectrometer
#8
Jinmei Wang, Linna Peng, Mengjun Shi, Changqin Li, Yan Zhang, Wenyi Kang
Different extracts of Angelica dahuricae were available for whitening or treating vitiligo clinically. They showed inhibitory or activating effects on tyrosinase, a rate-limiting enzyme of melanogenesis. This study aimed to identify active compounds on tyrosinase in water extract of Angelica dahurica Radix. We applied spectrum-effect relationship and component knock-out methods to make it clear. HPLC was used to obtain the specific chromatograms. The effects on tyrosinase activity were examined by measuring the oxidation rate of levodopa in vitro...
July 21, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28753056/gamma-irradiated-luteolin-inhibits-3-isobutyl-1-methylxanthine-induced-melanogenesis-through-the-regulation-of-creb-mitf-pi3k-akt-and-erk-pathways-in-b16bl6-melanoma-cells
#9
Eui-Baek Byun, Ha-Yeon Song, Sajid Mushtaq, Hye-Min Kim, Jung Ae Kang, Mi-So Yang, Nak-Yun Sung, Beom-Su Jang, Eui-Hong Byun
Luteolin was gamma irradiated at doses of 0, 15, 30, 50, 70, and 100 kGy. We observed that the luteolin peak decreased simultaneously with the appearance of new radiolytic peaks, using high-performance liquid chromatography (HPLC). The highest new radiolytic peak (GLM) of radiolytic product in gamma-irradiated luteolin was observed at a dose of 70 kGy, and the GLM was identified by nuclear magnetic resonance and high-performance-liquid-chromatography-quadrupole-time-of-flight (HPLC-Q-TOF) mass spectrometry...
August 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28750111/retinal-whitening-after-uncomplicated-cataract-surgery
#10
Natalie Wolkow, Patrick Oellers, John B Miller
No abstract text is available yet for this article.
July 27, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28745295/determination-of-heavy-metals-in-skin-whitening-cosmetics-using-microwave-digestion-and-inductively-coupled-plasma-atomic-emission-spectrometry
#11
Ayoub Abdullah Alqadami, Mu Naushad, Mohammad Abulhassan Abdalla, Mohammad Rizwan Khan, Zeid Abdullah Alothman, Saikh Mohammad Wabaidur, Ayman Abdel Ghfar
In this study, the determination of noxious heavy metals, cadmium (Cd), bismuth (Bi), mercury (Hg), titanium (Ti), lead (Pb) and metalloid arsenic (As) in skin-whitening cosmetics were examined using microwave digestion and inductively coupled plasma atomic emission spectrometry method. A complete digestion of cosmetics samples was achieved using a mixture of hydrofluoric acid/hydrogen peroxide/nitric acid. The quantification of the target compounds was done by standard addition method. The excellent quality parameters for instance, detection limits, As (4...
August 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/28739927/culture-extends-the-scope-of-evolutionary-biology-in-the-great-apes
#12
Andrew Whiten
Discoveries about the cultures and cultural capacities of the great apes have played a leading role in the recognition emerging in recent decades that cultural inheritance can be a significant factor in the lives not only of humans but also of nonhuman animals. This prominence derives in part from these primates being those with whom we share the most recent common ancestry, thus offering clues to the origins of our own thoroughgoing reliance on cumulative cultural achievements. In addition, the intense research focus on these species has spawned an unprecedented diversity of complementary methodological approaches, the results of which suggest that cultural phenomena pervade the lives of these apes, with potentially major implications for their broader evolutionary biology...
July 24, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28739924/the-extension-of-biology-through-culture
#13
Andrew Whiten, Francisco J Ayala, Marcus W Feldman, Kevin N Laland
No abstract text is available yet for this article.
July 24, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28734081/whitening-dependent-changes-of-fluorescence-of-extracted-human-teeth
#14
Natalie Pereira Sanchez, Aleksandar Aleksic, Miroslav Dramicanin, Rade D Paravina
OBJECTIVE: To evaluate in vitro the fluorescence properties of extracted human teeth whitened with 40% hydrogen peroxide. MATERIALS AND METHODS: A total of 28 extracted human teeth were pumiced for 1 minute using a low-speed dental handpiece and a disposable rubber cup. Pre-whitening fluorescence measurements (T0), maximum excitation (Exmax ), maximum emission (Emmax ), and maximum intensity (Imax 10(8) ), were performed using a spectrofluorometer. After T0 measurements, the teeth were whitened using the in-office method with 40% hydrogen peroxide, three times for 20 minutes...
July 22, 2017: Journal of Esthetic and Restorative Dentistry
https://www.readbyqxmd.com/read/28726389/antimelanogenic-effect-of-urolithin-a-and-urolithin-b-the-colonic-metabolites-of-ellagic-acid-in-b16-melanoma-cells
#15
Shang-Ta Wang, Wei-Chia Chang, Chen Hsu, Nan-Wei Su
Antimelanogenic agents from natural sources have been widely investigated. Urolithin A (UA) and B (UB), the main gut microflora metabolites of dietary ellagic acid derivatives, have various bioactivities such as anti-inflammatory and antiaging effects. In this study, the metabolites were found to possess depigmentation efficacy by suppressing tyrosinase activity. Both UA and UB could attenuate melanogenesis in B16 melanoma cells to 55.1 ± 3.8 and 76.4 ± 17.4% of control at noncytotoxic dosage, 10 μM, respectively...
August 16, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28725130/role-of-community-pharmacists-in-providing-oral-health-advice-in-the-eastern-province-of-saudi-arabia
#16
Hamad Al-Saleh, Thamir Al-Houtan, Khalid Al-Odaill, Basel Al-Mutairi, Mohammed Al-Muaybid, Tameem Al-Falah, Muhammad Ashraf Nazir
OBJECTIVE: To determine the frequency of patients seeking oral health advice and willingness of community pharmacists to provide oral health information in the Eastern Province of Saudi Arabia. METHODS: A cross-sectional study with sample size (n = 332) of randomly selected community pharmacists across the province. The questionnaire comprised of 25 questions divided into 3 sections. Frequency distributions of different categorical variables were calculated and Pearson's chi-square tests were performed to compare categorical variables...
July 2017: Saudi Dental Journal
https://www.readbyqxmd.com/read/28723567/cold-inducible-sirt6-regulates-thermogenesis-of-brown-and-beige-fat
#17
Lu Yao, Xiaona Cui, Qi Chen, Xiaoying Yang, Fude Fang, Jun Zhang, Guoqing Liu, Wanzhu Jin, Yongsheng Chang
Promoting development and function of brown and beige fat may reduce obesity. Here, we show that fat SIRT6 expression is markedly induced by cold exposure and a β-adrenergic agonist. Deletion of SIRT6 in adipose tissue impairs the thermogenic function of brown adipocytes, causing a morphological "whitening" of brown fat, reduced oxygen (O2) consumption, obesity, decreased core body temperature, and cold sensitivity. Fat SIRT6-deleted mice exhibit increased blood glucose levels, severe insulin resistance, and hepatic steatosis...
July 18, 2017: Cell Reports
https://www.readbyqxmd.com/read/28713957/soyasaponin%C3%A2-ag-inhibits-%C3%AE-%C3%A2-msh%C3%A2-induced-melanogenesis-in-b16f10-melanoma-cells-via-the-downregulation-of-trp%C3%A2-2
#18
Seung Hwan Yang, Aristides M Tsatsakis, George Tzanakakis, Hong-Suk Kim, Bao Le, Maria Sifaki, Demetrios A Spandidos, Chigen Tsukamoto, Kirill S Golokhvast, Boris N Izotov, Gyuhwa Chung
Saponins, which are glycosylated, represent a diverse group of biologically functional products in plants. In the present study, we investigated the effects of soyasaponin Ag, a secondary metabolite extracted from soybean, on α‑melanocyte-stimulating hormone (α‑MSH)‑induced melanin synthesis in B16F10 mouse melanoma cells and the underlying molecular mechanisms. To elucidate the mechanisms through which soyasaponin Ag inhibits melanin synthesis, we performed cellular tyrosinase activity assays and analyzed the expression of the melanogenesis‑related genes, tyrosinase, tyrosinase‑related protein (TRP)‑1 and TRP‑2...
September 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28713111/effect-of-hydrogen-and-carbamide-peroxide-in-bleaching-enamel-morphology-and-mineral-composition-in-vitro-study
#19
Carmen Llena, Irene Esteve, Leopoldo Forner
AIM: The aim of the study was to evaluate the bleaching effect, morphological changes, and variations in calcium (Ca) and phosphate (P) in the enamel with hydrogen peroxide (HP) and carbamide peroxide (CP) after the use of different application regimens. MATERIALS AND METHODS: Four groups of five teeth were randomly assigned, according to the treatment protocol: HP 37.5% applied for 30 or 60 minutes (HP30, HP60), CP 16% applied for 14 or 28 hours (CP14, CP28). Changes in dental color were evaluated, according to the following formula: ΔE = [(La-Lb)(2)+(aa-ab)(2) + (ba-bb)(2)](1/2)...
July 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28706755/effects-of-a-novel-whitening-formulation-on-dental-enamel
#20
Thair Takesh, Anik Sargsyan, Afarin Anbarani, Jessica Ho, Petra Wilder-Smith
OBJECTIVE: The goal of this study was to evaluate the enamel whitening effects of 2 new test formulations, one of which was a rinse, and the other a whitening strip. MATERIALS AND METHODS: Forty enamel chips were prepared from 20 healthy extracted teeth (2 from each tooth). After pre-staining and colorimetry to measure L* and b* values, 20 matched samples were immersed in either test or control rinses, and then colorimetry was performed again after 1 hr, 2 hr, 3 hr, 6 hr, 12 hr, 24 hr and 48 hrs (Each hour equates to one month of clinical use at the recommended dosage of 1 minute exposure 2 times a day)...
April 2017: Dentistry: Current Research
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