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https://www.readbyqxmd.com/read/29159178/zinc-containing-hydroxyapatite-enhances-cold-light-activated-tooth-bleaching-treatment-in-vitro
#1
Yi Li, Xinchang Shi, Wei Li
Cold-light bleaching treatment has grown to be a popular tooth whitening procedure in recent years, but its side effect of dental enamel demineralization is a widespread problem. The aim of this study was to synthesize zinc-substituted hydroxyapatite as an effective biomaterial to inhibit demineralization or increase remineralization. We synthesized zinc-substituted hydroxyapatite containing different zinc concentrations and analysed the product using X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, and energy dispersive spectrometer (EDS)...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29150154/cutaneous-squamous-cell-carcinomas-scc-associated-with-cosmetic-skin-whitening-8-cases-reported-in-senegal
#2
F Ly, P Diousse, C Ndiaye, A Déme, B A Diatta, M T Ndiaye, M Diallo, A Diop, A D Kebe, F Fall, A Kane
BACKGROUND: The cosmetic use of bleaching products is common among women from sub-Saharan Africa. The most frequently used products are highly potent corticosteroids (clobetasol propionate) and hydroquinone. Herein, we report 8 cases of SCC in women using skin bleaching products for cosmetic purposes. Our aim is to describe the epidemiological, clinical and pathological aspects of the carcinomas observed during the course of skin lightening. METHODS: We conducted a descriptive multicentre study from August 2005 to January 2016 in three dermatology units in Senegal...
November 14, 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/29146323/development-and-validation-of-a-screening-and-quantification-method-for-simultaneous-determination-of-seven-fluorescent-whitening-agents-in-commercial-flour-using-uplc-ms-ms
#3
Yuluan Wu, Yanping Xian, Xindong Guo, Liwei Chen, Xiaojuan Zhao, Bin Wang, Li Wang
A sensitive UPLC-MS/MS method was established for the simultaneous determination of seven fluorescent whitening agents in flour matrix. Samples were ultrasonically extracted by trichloromethane-acetone. Then analytes were separated on a C18 column and detected by MS/MS. The developed method was validated in terms of the linearity, matrix effect, accuracy and precision. The method showed a good linearity (r>0.997) for all analytes in their respective concentration ranges. The LOQ for seven analytes were in the range of 2...
March 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29144879/effectiveness-and-impact-of-the-walking-bleach-technique-on-esthetic-self-perception-and-psychosocial-factors-a-randomized-double-blind-clinical-trial
#4
C Bersezio, J Martin, F Peña, M Rubio, J Estay, R Vernal, Ob Oliveira Junior, E Fernández
OBJECTIVE: This trial evaluates the impact of psychosocial and esthetic self-perceptions of patients undergoing nonvital tooth bleaching using the walking bleach technique. We also assessed the clinical effectiveness of bleaching tooth discoloration. METHODS: Fifty volunteers with nonvital tooth discoloration were enrolled. Teeth were randomized into two groups: 35% hydrogen peroxide (n=25) and 37% carbamide peroxide (n=25). Intracoronal bleaching was performed over four sessions using the walking bleach technique...
November 2017: Operative Dentistry
https://www.readbyqxmd.com/read/29144876/effects-of-at-home-bleaching-in-smokers-30-month-follow-up
#5
J L de Geus, E Fernández, S Kossatz, A D Loguercio, A Reis
OBJECTIVE: This clinical study evaluated the color longevity after 30 months of at-home bleaching with 10% carbamide peroxide (CP) in smokers and nonsmokers. METHODS: Sixty patients, 30 smokers and 30 nonsmokers, were subjected to bleaching with 10% CP (Whiteness Perfect-FGM) for three hours daily for three weeks. The color was measured at baseline and at one month and 30 months after the completion of dental bleaching using the shade guide Vita classical organized by value (ΔSGU) and the shade guide Vita Bleachedguide 3D-MASTER...
November 2017: Operative Dentistry
https://www.readbyqxmd.com/read/29142412/tyrosinase-inhibitory-activities-of-carissa-opaca-stapf-ex-haines-roots-extracts-and-their-phytochemical-analysis
#6
Wajeeha Malik, Dildar Ahmed, Sania Izhar
Objective: Carissa opaca is a medicinal plant with rich folkloric applications. The present research was conducted to explore the tyrosinase inhibitory potential of aqueous decoction (AD) and methanolic extract (ME) of roots of C. opaca and its fractions in various solvents and their phytochemical analysis. Materials and Methods: AD of the dried powdered roots of C. opaca was prepared by boiling in water. ME was prepared by cold maceration. Its fractions were obtained in solvents of increasing polarity, i...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29130776/new-insights-into-effects-of-aromatic-amino-acids-on-hydroxyapatite
#7
Y R Guo, X Yang, X W Feng, Y Sa, M Wang, P Li, T Jiang
Biomimetics inspired by superstructures and extraordinary properties of teeth have resulted in tooth repair and the generation of novel materials. However, little attention has been paid to tooth color, whose origin remains unknown. Based on recent studies, fluorophores-mainly aromatic amino acids (AAAs) in proteins-might be responsible for tooth color. We synthesized carbonated hydroxyapatite (HA; the mineral phase of teeth) in the presence of different amino acids (AAs; the basic units of protein matrix of teeth) as a simplified model of teeth to explore the color source at the AA level...
November 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/29126484/performance-of-electrokinetic-stacking-enhanced-paper-based-analytical-device-with-smartphone-for-fast-detection-of-fluorescent-whitening-agent
#8
Yi-Zhen Song, Xiu-Xiu Zhang, Biao Ma, Zhi-Yong Wu, Zi-Qiang Zhang
Quantification is a fundamental aspect of performance of an analytical system. Paper-based analytical device (PAD) as an on-site detection platform has drawn wide attention mainly due to its portability and cost effectiveness. In this work, a portable and low-cost PAD for online preconcentration and sensitive determination of fluorescent whitening agent (FWA) was demonstrated, which was consisted of ultra violet light-emitting diode (UV LED), macro-focusing lens, smartphone and miniaturized DC voltage source...
December 1, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29125909/calcium-phosphate-microspheres-as-a-delivery-vehicle-for-tooth-bleaching-agents
#9
T Mellgren, T Qin, C Öhman-Mägi, Y Zhang, B Wu, W Xia, H Engqvist
Bleaching of vital teeth has become common practice in cosmetic dentistry today. Tooth sensitivity and demineralization of the enamel are, however, common side effects associated with hydrogen and carbamide peroxide bleaching. This study investigated if calcium phosphate microspheres, which have remineralizing properties, could be used as an additive without hindering the diffusion of the bleaching agent and if the spheres could be used as a carrier for carbamide peroxide. A remineralizing agent could increase the safety of bleaching and decrease the severity of its side effects...
November 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/29124794/effect-of-home-bleaching-on-the-translucency-of-cad-cam-systems
#10
Muhammet Karci, Necla Demir
PURPOSE: To evaluate the effect of a home bleaching agent (Opalescence PF) on the translucency of CAD/CAM ceramic systems. MATERIALS AND METHODS: The 28 sintered ceramic specimens (IPS Empress CAD and IPS e.max CAD; 15 mm long, 10 mm wide, 1 mm thick) were divided into two subgroups as control and bleaching groups (n = 7). Carbamide peroxide (CP), 16%, home bleaching agent was applied onto the surface of each specimen for 6 hours per day for 7 days. A spectrophotometer (VITA Easyshade Advance) was used to measure the CIE L(*) a(*) b(*) coordinates and the reflectance value (Y) of the specimens on white and black backgrounds...
November 10, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/29123632/management-of-post-endodontic-retreatment-pain-with-low-level-laser-therapy
#11
Mohammad Asnaashari, Hengameh Ashraf, Amir Houshang Daghayeghi, Seyed Masoud Mojahedi, Saranaz Azari-Marhabi
Introduction: Pharmacotherapy with analgesics and non-steroidal anti-inflammatory drugs has been traditionally used to relief post-operative pain of endodontic treatments. However, due to the side effects reported for these drugs, some efforts have been made to decrease the post-operative pain of the endodontic treatments through laser irradiation. The present study aimed to evaluate the effects of low level laser therapy (LLLT) on the reduction of pain after root canal retreatment. Methods: In this clinical trial, 61 patients requiring endodontic retreatments in posterior teeth were selected...
2017: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/29123306/book-review-tooth-whitening-an-evidence-based-perspective
#12
G Fenton
No abstract text is available yet for this article.
November 10, 2017: British Dental Journal
https://www.readbyqxmd.com/read/29121910/thai-plants-with-high-antioxidant-levels-free-radical-scavenging-activity-anti-tyrosinase-and-anti-collagenase-activity
#13
Moragot Chatatikun, Anchalee Chiabchalard
BACKGROUND: Ultraviolet radiation from sunlight induces overproduction of reactive oxygen species (ROS) resulting in skin photoaging and hyperpigmentation disorders. Novel whitening and anti-wrinkle compounds from natural products have recently become of increasing interest. The purpose of this study was to find products that reduce ROS in 14 Thai plant extracts. METHODS: To determine total phenolic and flavonoid content, antioxidant activity, anti-tyrosinase activity and anti-collagenase activity, we compared extracts of 14 Thai plants prepared using different solvents (petroleum ether, dichloromethane and ethanol)...
November 9, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29121140/complications-of-cosmetic-eye-whitening
#14
Ann Q Tran, Catherine Hoppener, Nandini Venkateswaran, Daniel S Choi, Wendy W Lee
Introduced in 2008 and subsequently popularized in South Korea, cosmetic eye whitening has been offered as a treatment of chronic conjunctival hyperemia. Patients undergo conjunctivectomy with topical mitomycin C (MMC) 0.02% application to achieve a whitened appearance from bleaching of avascular sclera. Much speculation has arisen from this procedure given the limited available evidence on its efficacy and safety. A literature search was performed to review common complications of cosmetic eye whitening, including chronic conjunctival epithelial defects, scleral thinning, avascular zones in the sclera, dry eye syndrome, and diplopia requiring strabismus surgery...
September 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/29120637/protection-from-below-stabilizing-hydrogenated-graphene-using-graphene-underlayers
#15
Keith E Whitener, Jeremy T Robinson, Paul E Sheehan
We show that dehydrogenation of hydrogenated graphene proceeds much more slowly for bilayer systems than for single layer systems. We observe that an underlayer of either pristine or hydrogenated graphene will protect an overlayer of hydrogenated graphene against a number of chemical oxidants, thermal dehydrogenation, and degradation in an ambient environment over extended periods of time. Chemical protection depends on the ease of oxidant intercalation, with good intercalants such as Br2 demonstrating much higher reactivity than poor intercalants such as 1,2-dichloro-4,5-dicyanonbenzoquinone (DDQ)...
November 17, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29118527/unusual-pattern-of-whitening-of-eyebrows-following-sunitinib-therapy-a-case-report-with-brief-review-of-literature
#16
Chaturbhuj R Agrawal, Vineet Talwar, Venkata Pradeep Babu, Parveen Jain, Pankaj Goyal
Sunitinib is a vascular endothelial growth factor receptor inhibitor which has shown high activity in metastatic renal cell carcinoma (mRCC) patients and is now widely used for the same. It is generally well tolerated, but sometimes, it exhibits a distinct pattern of novel side effects that require monitoring and management. Important known side effect of sunitinib includes fatigue, diarrhea, anorexia, skin toxicity, and hypertension which need special mention. Considering its effectiveness in first-line setting in mRCC and paucity of other good options, utmost efforts are made to continue it with identification of side effects which may require only slight dose modification or no dose alteration...
October 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/29115989/clusterin-protects-neurons-against-intracellular-proteotoxicity
#17
Jenna M Gregory, Daniel R Whiten, Rebecca A Brown, Teresa P Barros, Janet R Kumita, Justin J Yerbury, Sandeep Satapathy, Karina McDade, Colin Smith, Leila M Luheshi, Christopher M Dobson, Mark R Wilson
It is now widely accepted in the field that the normally secreted chaperone clusterin is redirected to the cytosol during endoplasmic reticulum (ER) stress, although the physiological function(s) of this physical relocation remain unknown. We have examined in this study whether or not increased expression of clusterin is able to protect neuronal cells against intracellular protein aggregation and cytotoxicity, characteristics that are strongly implicated in a range of neurodegenerative diseases. We used the amyotrophic lateral sclerosis-associated protein TDP-43 as a primary model to investigate the effects of clusterin on protein aggregation and neurotoxicity in complementary in vitro, neuronal cell and Drosophila systems...
November 7, 2017: Acta Neuropathologica Communications
https://www.readbyqxmd.com/read/29115012/3-o-glyceryl-2-o-hexyl-ascorbate-suppresses-melanogenesis-by-interfering-with-intracellular-melanosome-transport-and-suppressing-tyrosinase-protein-synthesis
#18
Norihisa Taira, Yushi Katsuyama, Masato Yoshioka, Yuri Okano, Hitoshi Masaki
BACKGROUND: Ascorbic acid (AsA) has multifunctional benefits on skin beauty, such as the reduction in oxidative stress and the induction of collagen production. Among them, the prevention and improvement of skin pigmentation by AsA is a most important benefit for people. However, it is well known that AsA not only is quite unstable in formulations but it also has a low capability of skin penetration due to its hydrophilic property. In addition, existing water-soluble AsA derivatives that were developed to improve its stability also have low skin penetration...
November 7, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29109310/in-situ-effect-of-nanohydroxyapatite-paste-in-enamel-teeth-bleaching
#19
Yasmin Sb de Lima Gomes, Larissa D Alexandrino, Cristiane de M Alencar, Eliane B Alves, Kelson Cf Faial, Cecy M Silva
AIM: Evaluate in situ the effect of nanohydroxyapatite paste (nano-HAP) before bleaching with hydrogen peroxide 35% (HP35%) by ion chromatography (IC) Knoop hardness number (KHN) and tristimulus colorimetry (TC). MATERIALS AND METHODS: A total of 60 fragments were obtained from third molars included (3 mm × 3 mm × 3 mm) and the specimens were divided into three groups (n = 20): Gas chromatography (CG) (negative control group) = no bleaching; HP35% (positive control group) = HP35% whitening (whiteness HP35%); nano-HAP = application for 10 minutes before bleaching treatment + HP35%...
November 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/29109122/the-type-1-diabetes-resistance-locus-idd22-controls-trafficking-of-autoreactive-ctls-into-the-pancreatic-islets-of-nod-mice
#20
Robert L Whitener, Lisa Gallo Knight, Jianwei Li, Sarah Knapp, Shuyao Zhang, Mani Annamalai, Vadim M Pliner, Dongtao Fu, Ilian Radichev, Christina Amatya, Alexei Savinov, Arif Yurdagul, Shuai Yuan, John Glawe, Christopher G Kevil, Jing Chen, Scott E Stimpson, Clayton E Mathews
Type 1 diabetes (T1D) has a strong genetic component. The insulin dependent diabetes (Idd)22 locus was identified in crosses of T1D-susceptible NOD mice with the strongly T1D-resistant ALR strain. The NODcALR-(D8Mit293-D8Mit137)/Mx (NOD-Idd22) recombinant congenic mouse strain was generated in which NOD mice carry the full Idd22 confidence interval. NOD-Idd22 mice exhibit almost complete protection from spontaneous T1D and a significant reduction in insulitis. Our goal was to unravel the mode of Idd22-based protection using in vivo and in vitro models...
November 6, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
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