keyword
https://read.qxmd.com/read/38611669/antenatal-determinants-of-postnatal-renal-function-in-fetal-megacystis-a-systematic-review
#1
REVIEW
Ugo Maria Pierucci, Irene Paraboschi, Guglielmo Mantica, Sara Costanzo, Angela Riccio, Giorgio Giuseppe Orlando Selvaggio, Gloria Pelizzo
Introduction : To evaluate the clinical usefulness of demographic data, fetal imaging findings and urinary analytes were used for predicting poor postnatal renal function in children with congenital megacystis. Materials and methods : A systematic review was conducted in MEDLINE's electronic database from inception to December 2023 using various combinations of keywords such as "luto" [All Fields] OR "lower urinary tract obstruction" [All Fields] OR "urethral valves" [All Fields] OR "megacystis" [All Fields] OR "urethral atresia" [All Fields] OR "megalourethra" [All Fields] AND "prenatal ultrasound" [All Fields] OR "maternal ultrasound" [All Fields] OR "ob-stetric ultrasound" [All Fields] OR "anhydramnios" [All Fields] OR "oligohydramnios" [All Fields] OR "renal echogenicity" [All Fields] OR "biomarkers" [All Fields] OR "fetal urine" [All Fields] OR "amniotic fluid" [All Fields] OR "beta2 microglobulin" [All Fields] OR "osmolarity" [All Fields] OR "proteome" [All Fields] AND "outcomes" [All Fields] OR "prognosis" [All Fields] OR "staging" [All Fields] OR "prognostic factors" [All Fields] OR "predictors" [All Fields] OR "renal function" [All Fields] OR "kidney function" [All Fields] OR "renal failure" [All Fields]...
April 2, 2024: Diagnostics
https://read.qxmd.com/read/38592253/labor-induction-in-women-with-isolated-polyhydramnios-at-term-a-multicenter-retrospective-cohort-analysis
#2
JOURNAL ARTICLE
Yael Lerner, Tzuria Peled, Morag Yehushua, Reut Rotem, Ari Weiss, Hen Y Sela, Sorina Grisaru-Granovsky, Misgav Rottenstreich
Background: With the increasing popularity of elective induction after 39 + 0 weeks, the question of whether induction of labor (IOL) is safe in women with isolated polyhydramnios has become more relevant. We aimed to evaluate the pregnancy outcomes associated with IOL among women with and without isolated polyhydramnios. Methods: This was a multicenter retrospective cohort that included women who underwent induction of labor at term. The study compared women who underwent IOL due to isolated polyhydramnios to low-risk women who underwent elective IOL due to gestational age only...
February 29, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38588889/pioneering-a-chick-embryo-model-to-explore-the-intrauterine-etiology-of-developmental-dysplasia-of-the-hip-in-oligohydramnios-conditions
#3
JOURNAL ARTICLE
Shaoting Luo, Yufan Chen, Weizheng Zhou, Federico Canavese, Lianyong Li
OBJECTIVE: To explore the impact of oligohydramnios on fetal movement and hip development, given its association with Developmental Dysplasia of the Hip (DDH) but unclear mechanisms. METHODS: Chick embryos were divided into four groups based on the severity of oligohydramnios induced by amniotic fluid aspiration (control, 0.2 mL, 0.4 mL, 0.6 mL). Fetal movement was assessed by detection of movement and quantification of residual amniotic fluid volume. Hip joint development was assessed by gross anatomic analysis, micro-computed tomography (micro-CT) for cartilage assessment, and histologic observation at multiple time points...
April 6, 2024: Osteoarthritis and Cartilage
https://read.qxmd.com/read/38583714/indicated-versus-universal-third-trimester-ultrasound-examination-in-low-risk-pregnancies-a-pre-and-post-intervention-study
#4
JOURNAL ARTICLE
Aaron W Roberts, Mr John Hotra, Eleazar Soto, Claudia Pedroza, Baha M Sibai, Sean C Blackwell, Suneet P Chauhan
BACKGROUND: In low-risk pregnancies, third trimester ultrasound examination is indicated if fundal height measurement and gestational age discrepancy is observed. Despite potential improvement in detection of ultrasound abnormality, prior trials to date on universal third trimester ultrasound examination in low-risk pregnancies, compared to indicated ultrasound examination, have not demonstrated improvement in neonatal or maternal adverse outcomes. OBJECTIVE: The primary objective was to determine if universal third trimester ultrasound examination in low-risk pregnancies could attenuate composite neonatal adverse outcome...
April 5, 2024: American journal of obstetrics & gynecology MFM
https://read.qxmd.com/read/38557708/association-of-fetal-catecholamines-with-neonatal-hypoglycemia
#5
JOURNAL ARTICLE
Henrike Hoermann, Martijn van Faassen, Marcia Roeper, Carsten Hagenbeck, Diran Herebian, Anneke C Muller Kobold, Juergen Dukart, Ido P Kema, Ertan Mayatepek, Thomas Meissner, Sebastian Kummer
IMPORTANCE: Perinatal stress and fetal growth restriction increase the risk of neonatal hypoglycemia. The underlying pathomechanism is poorly understood. In a sheep model, elevated catecholamine concentrations were found to suppress intrauterine insulin secretion, followed by hyperresponsive insulin secretion once the adrenergic stimulus subsided. OBJECTIVE: To determine whether neonates with risk factors for hypoglycemia have higher catecholamine concentrations in umbilical cord blood (UCB) and/or amniotic fluid (AF) and whether catecholamines are correlated with postnatal glycemia...
April 1, 2024: JAMA Pediatrics
https://read.qxmd.com/read/38539138/incidence-and-development-of-validated-mortality-prediction-model-among-asphyxiated-neonates-admitted-to-neonatal-intensive-care-unit-at-felege-hiwot-comprehensive-specialized-hospital-bahir-dar-northwest-ethiopia-2021-retrospective-follow-up-study
#6
JOURNAL ARTICLE
Yibeltal Shitu Tegegne, Tilahun Yemanu Birhan, Habtamu Takele, Fantahun Ayenew Mekonnen
INTRODUCTION: Perinatal asphyxia is failure to maintain normal breathing at birth. World Health Organization indicates that perinatal asphyxia is the third major cause of neonatal mortality in developing countries accounting for 23% of neonatal deaths every year. At global and national level efforts have done to reduce neonatal mortality, however fatalities from asphyxia remains high in Ethiopia (24%). And there are no sufficient studies to show incidence and prediction of mortality among asphyxiated neonates...
March 28, 2024: BMC Pediatrics
https://read.qxmd.com/read/38534523/profile-of-a-multivariate-observation-under-destructive-sampling-a-monte-carlo-approach-to-a-case-of-spina-bifida
#7
JOURNAL ARTICLE
Tianyuan Guan, Rigwed Tatu, Koffi Wima, Marc Oria, Jose L Peiro, Chia-Ying Lin, Marepalli B Rao
A biodegradable hybrid polymer patch was invented at the University of Cincinnati to cover gaps on the skin over the spinal column of a growing fetus, characterized by the medical condition spina bifida. The inserted patch faces amniotic fluid (AF) on one side and cerebrospinal fluid on the other side. The goal is to provide a profile of the roughness of a patch over time at 0, 4, 8, 12, and 16 weeks with a 95% confidence band. The patch is soaked in a test tube filled with either amniotic fluid (AF) or phosphate-buffered saline (PBS) in the lab...
March 3, 2024: Bioengineering
https://read.qxmd.com/read/38456522/implementation-of-sonopartogram-multicenter-feasibility-study
#8
JOURNAL ARTICLE
N M W Lee, S L Lau, Y K Yeung, C P H Chiu, F Liu, Y Y Lau, A M Fidalgo, M J Cuerva, A Aquise, L Nguyen-Hoang, M M Gil, L C Poon
OBJECTIVES: Well-established clinical practice to assess progress in labor involves routine abdominal palpation and vaginal examination (VE). However, VE is subjective, poorly reproducible and painful for women. In this study, our aim is to evaluate the feasibility of systematically integrating transabdominal and transperineal ultrasound assessment of fetal position, psAOP, HPD and SCD to monitor labor progress in women undergoing induction of labor (IOL). We also aim at determining if ultrasound can reduce women's pain during examinations...
March 8, 2024: Ultrasound in Obstetrics & Gynecology
https://read.qxmd.com/read/38430043/exploring-the-prognostic-significance-of-%C3%AE-hcg-levels-in-cervicovaginal-secretions-and-maternal-risk-factors-for-early-birth
#9
JOURNAL ARTICLE
Homood Alharbi, Abdualrahman Saeed Alshehry, Ahmed Alsadoun, Mohammad Ahmad, Mustafa Sawsan Aloahd
Preterm birth is one of the leading causes of death in the perinatal period, this study was conducted to investigate the predictive value of β-HCG Levels in cervicovaginal secretions and maternal risk factors in preterm delivery. This cross-sectional study was conducted over a six-month period from January 1 to June 30, 2021, in  Baghdad hospitals. The data were collected and used from the mothers who went to the hospital for delivery. Demographic information of patients and some risk factors were investigated...
February 29, 2024: Cellular and Molecular Biology
https://read.qxmd.com/read/38420210/evaluation-of-stability-and-safety-of-equine-mesenchymal-stem-cells-derived-from-amniotic-fluid-for-clinical-application
#10
JOURNAL ARTICLE
Eun Young Kim, Eun Ji Lee, Ryoung Eun Kim, Tae Young Kil, Min Kyu Kim
Amniotic fluid mesenchymal stem cells (AF-MSCs), which can be obtained from fetal tissue, reportedly have self-renewal capacity and multi-lineage differentiation potential. The aim of this study was to identify the biological characteristics of AF-MSCs and evaluate their stability and safety in long-term culture. To confirm the biological characteristics of AF-MSCs, morphology, proliferation capacity, karyotype, differentiation capacity, gene expression level, and immunophenotype were analyzed after isolating AF-MSCs from equine amniotic fluid...
2024: Frontiers in Veterinary Science
https://read.qxmd.com/read/38418104/perinatal-outcome-in-pregnant-women-with-isolated-oligohydramnios-diagnosed-with-the-single-deepest-pocket-method
#11
JOURNAL ARTICLE
Ulf Dammer, Jutta Pretscher, Christel Weiss, Michael Schneider, Florian Faschingbauer, Matthias W Beckmann, Sven Kehl
AIM: The aim of this study was to investigate perinatal outcome in singleton pregnancies at term with isolated oligohydramnios, diagnosed by using the single deepest pocket method. PATIENTS AND METHODS: In this historic cohort study, the perinatal outcomes of 196 women with isolated oligohydramnios at term, diagnosed by using the single deepest pocket method, were compared to 8,676 women with normal amniotic fluid volume. The primary outcome measure was the Cesarean section rate...
2024: In Vivo
https://read.qxmd.com/read/38406089/frequency-of-maternal-anemia-in-patients-presenting-with-preterm-premature-rupture-of-membranes
#12
JOURNAL ARTICLE
Naila Khan, Saima Khattak
BACKGROUND: Preterm premature rupture of membranes (PPROM) is the rupture of fetal membranes before 38 weeks of gestation. The etiology is multifactorial. Maternal anemia is one of the factors leading to PPROM. This study aims to determine the frequency of maternal anemia in patients presenting with PPROM. MATERIALS AND METHODS: This cross-sectional study was carried out at the Department of Obstetrics and Gynecology, Lady Reading Hospital, Peshawar. This study was conducted from July 1 to December 31, 2021...
January 2024: Curēus
https://read.qxmd.com/read/38395796/prediction-of-unplanned-cesarean-section-using-measurable-maternal-and-fetal%C3%A2-characteristics-ethiopia-a-retrospective-cohort-study
#13
JOURNAL ARTICLE
Bezawit Melak Fente, Mengstu Melkamu Asaye, Temesgen Worku Gudayu, Muhabaw Shumye Mihret, Getayeneh Antehunegn Tesema
BACKGROUND: When a pregnant woman experiences unusual circumstances during a vaginal delivery, an unplanned cesarean section may be necessary to save her life. It requires knowledge and quick assessment of the risky situation to decide to perform an unplanned cesarean section, which only occurs in specific obstetric situations. This study aimed to develop and validate a risk prediction model for unplanned cesarean sections among laboring women in Ethiopia. METHOD: A retrospective follow-up study was conducted...
February 23, 2024: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/38382607/microplastics-in-maternal-amniotic-fluid-and-their-associations-with-gestational-age
#14
JOURNAL ARTICLE
Jiyang Xue, Zhendong Xu, Xiaobing Hu, Yan Lu, Yan Zhao, Hai Zhang
Microplastics (MPs) pollution is a growing global concern due to its potential threat to human health, particularly concerning fetal health. Nevertheless, few studies have examined the sources of fetal MPs exposure and its impact on fetal development. In this study, MPs levels in maternal amniotic fluid (AF) and their associations with measures of fetal growth were investigated. Specifically, 40 human AF samples were collected to determine the presence and characteristics of MPs using laser direct infrared (LD-IR) spectroscopy...
February 19, 2024: Science of the Total Environment
https://read.qxmd.com/read/38337548/measurement-of-calprotectin-and-pth-in-the-amniotic-fluid-of-early-second-trimester-pregnancies-and-their-impact-on-fetuses-with-growth-disorders-are-their-levels-related-to-oxidative-stress
#15
JOURNAL ARTICLE
George Maroudias, Dionysios Vrachnis, Alexandros Fotiou, Nikolaos Loukas, Aimilia Mantzou, Vasileiοs Pergialiotis, George Valsamakis, Nikolaos Machairiotis, Sofoklis Stavros, Periklis Panagopoulos, Panagiotis Vakas, Christina Kanaka-Gantenbein, Petros Drakakis, Nikolaos Vrachnis
Background : During the early stages of human fetal development, the fetal skeleton system is chiefly made up of cartilage, which is gradually replaced by bone. Fetal bone development is mainly regulated by the parathyroid hormone parathormone (PTH) and PTH-related protein, with specific calprotectin playing a substantial role in cell adhesion and chemotaxis while exhibiting antimicrobial activity during the inflammatory osteogenesis process. The aim of our study was to measure the levels of PTH and calprotectin in early second trimester amniotic fluid and to carry out a comparison between the levels observed among normal full-term pregnancies (control group) and those of the groups of embryos exhibiting impaired or enhanced growth...
February 1, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38329550/predictive-potential-of-various-plasma-inflammation-angiogenesis-and-extracellular-matrix-remodeling-associated-mediators-for-intra-amniotic-inflammation-and-or-microbial-invasion-of-the-amniotic-cavity-in-preterm-labor
#16
JOURNAL ARTICLE
Eunwook Joo, Subeen Hong, Kyo Hoon Park, Hyeon Ji Kim, Min Jung Lee, Sue Shin
PURPOSE: To determine whether various inflammatory-, angiogenic/anti-angiogenic-, and extracellular matrix remodeling-associated proteins in plasma, alone or in combination with conventional blood-based markers, can predict intra-amniotic inflammation and/or microbial invasion of the amniotic cavity (IAI/MIAC) in women with spontaneous preterm labor (PTL). METHODS: A total of 193 singleton pregnant women with PTL (23-33 weeks) were included in this retrospective cohort study...
February 8, 2024: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/38318268/maternal-serum-soluble-fms-like-tyrosine-kinase-1-to-placental-growth-factor-ratio-distinguishes-growth-restricted-from-non-growth-restricted-small-for-gestational-age-fetuses
#17
JOURNAL ARTICLE
Prithi Rajiv, Thomas Cade, Jennifer Dean, Gabriel Davis Jones, Shaun P Brennecke
BACKGROUND: Fetal growth restriction secondary to chronic placental insufficiency is a major cause of perinatal morbidity and mortality. A significant proportion of fetuses with fetal growth restriction are small for gestational age, defined as a birthweight of ≤10th percentile. However, not all small-for-gestational-age fetuses are growth restricted. Some are constitutionally small and otherwise healthy. It is important to distinguish between small-for-gestational-age fetuses with and without fetal growth restriction to ensure appropriate interventions in small-for-gestational-age fetuses with fetal growth restriction and to minimize unnecessary interventions in healthy small-for-gestational-age fetuses...
February 2024: AJOG global reports
https://read.qxmd.com/read/38290925/intra-amniotic-infection-and-or-inflammation-is-associated-with-fetal-cardiac-concentric-hypertrophy-and-diastolic-dysfunction-in-preterm-labor-and-preterm-prelabor-rupture-of-membranes
#18
JOURNAL ARTICLE
Clara Murillo, Claudia Rueda, Marta Larroya, David Boada, Laia Grau, Júlia Ponce, Ana Herranz, Olga Gómez, Silvia Ferrero, Vicente Andreu-Fernández, Eduard Gratacós, Fàtima Crispi, Montse Palacio, Teresa Cobo
BACKGROUND: Preterm delivery is associated with cardiovascular remodeling and dysfunction in children and adults. However, it is unknown whether these effects are caused by the neonatal consequences of preterm birth or if these are already present in utero. OBJECTIVE: We evaluated fetal cardiac morphology and function in fetuses of mothers admitted for preterm labor or preterm prelabor rupture of membranes and the association of these changes with the presence of intra-amniotic infection and/or inflammation...
January 9, 2024: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38277050/one-year-results-of-a-phase-i-ii-randomized-double-masked-placebo-controlled-study-of-processed-amniotic-fluid-drops-after-prk
#19
JOURNAL ARTICLE
Malka Davina Kirschenbaum, Katherine S Hu, Colin S Ip, Amy Lin, Jan Pierce, Richard Holubkov, Hailey Jensen, Mark D Mifflin
PURPOSE: The aim of this study was to evaluate the 1-year outcomes of using processed amniotic fluid (pAF) postoperatively after photorefractive keratectomy (PRK). METHODS: Sixty-one participants were randomized to receive either placebo or pAF drops. The drops were instilled 4 times daily for 1 week after PRK along with routine postoperative medications. The primary outcome measures included uncorrected visual acuity, topographic corneal irregularity measurement, and surface staining over 1 year...
January 26, 2024: Cornea
https://read.qxmd.com/read/38271755/carvacrol-in-ovo-delivery-optimization-and-flow-dynamics-in-broiler-chicken-eggs
#20
JOURNAL ARTICLE
Mila M Y Meijer, Henry van den Brand, Shahram Niknafs, Terra Stark, Marta Navarro, Asad A Khaskheli, Eugeni Roura
In ovo delivery of carvacrol, the primary active compound in oregano essential oil (OEO) has the potential to enhance gut development in broilers. This study aimed to optimize in ovo application of OEO by investigating day and site of injection and delivery of carvacrol to different embryonic tissues. In Experiment 1, 2 d of injection (embryonic day (E) 12 or 17.5) and 3 sites of injection for OEO (air cell, amniotic fluid, or yolk) were evaluated based on hatchability and posthatching performance. Experiment 2 aimed to examine the impact of combining OEO with the nonionic surfactant polysorbate 80 (p80) at ratios to carvacrol of 0:0, 0:1, 0...
January 8, 2024: Poultry Science
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