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amniotic fluid measurements

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https://www.readbyqxmd.com/read/29629694/effect-of-gastric-lavage-on-meconium-aspiration-syndrome-and-feed-intolerance-in-vigorous-infants-born-with-meconium-stained-amniotic-fluid-a-randomized-control-trial
#1
Shrishail Gidaganti, M M A Faridi, Manish Narang, Prerna Batra
OBJECTIVE: To compare the incidence of meconium aspiration syndrome and feed intolerance in infants born through meconium stained amniotic fluid with or without gastric lavage performed at birth. SETTING: Neonatal unit of a teaching hospital in New Delhi, India. DESIGN: Parallel group unmasked randomized controlled trial. PARTICIPANTS: 700 vigorous infants of gestational age ≥34 weeks from through meconium stained amniotic fluid...
March 15, 2018: Indian Pediatrics
https://www.readbyqxmd.com/read/29607557/maternal-hemodynamics-fetal-biometry-and-dopplers-in-pregnancies-followed-up-for-suspected-fetal-growth-restriction
#2
Llinos A Roberts, Hua Zen Ling, Liona Poon, Kypros H Nicolaides, Nikos A Kametas
OBJECTIVES: To assess whether in a cohort of patients with small for gestational age (SGA) foetuses with estimated fetal weight ≤10th percentile, maternal hemodynamics, fetal biometry and Dopplers at presentation, can predict the subsequent development of abnormal fetal Dopplers or delivery with birthweight <3rd percentile. METHODS: The study population comprised of 86 singleton pregnancies with SGA fetuses presenting at a median gestational age of 32 (range 26-35) weeks...
April 1, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29575915/transfer-of-egg-white-proteins-and-activation-of-proteases-during-the-development-of-anas-platyrhynchos-domestica-embryo
#3
Seba Jamal Shbailat, Razan Ataallah Abuassaf
The route of egg white transfer into the yolk and the mechanisms underlying the digestion of egg proteins are unexplored in the fertilized egg of the duck, Anas platyrhynchos domestica. Here, we investigated the route(s) of egg white transfer and we determined the type of activated proteases during duck embryo development. Initially, we tested the electrophoretic patterns of egg proteins throughout development. Then, we used lysozyme as a reference protein to follow egg white transfer and we measured its activity...
March 2018: Acta Biologica Hungarica
https://www.readbyqxmd.com/read/29556840/contribution-of-tandem-mass-spectrometry-to-the-diagnosis-of-lysosomal-storage-disorders
#4
Monique Piraud, Magali Pettazzoni, Pamela Lavoie, Séverine Ruet, Cécile Pagan, David Cheillan, Philippe Latour, Christine Vianey-Saban, Christiane Auray-Blais, Roseline Froissart
Tandem mass spectrometry (MS/MS) is a highly sensitive and specific technique. Thanks to the development of triple quadrupole analyzers, it is becoming more widely used in laboratories working in the field of inborn errors of metabolism. We review here the state of the art of this technique applied to the diagnosis of lysosomal storage disorders (LSDs) and how MS/MS has changed the diagnostic rationale in recent years. This fine technology brings more sensitive, specific, and reliable methods than the previous biochemical ones for the analysis of urinary glycosaminoglycans, oligosaccharides, and sialic acid...
March 19, 2018: Journal of Inherited Metabolic Disease
https://www.readbyqxmd.com/read/29549721/analysis-of-cytokines-ifn-%C3%AE-tnf-%C3%AE-tgf-%C3%AE-and-nitric-oxide-in-amniotic-fluid-and-serum-of-pregnant-women-with-toxoplasmosis-in-southern-brazil
#5
Ariella Andrade Marchioro, Cristiane Maria Colli, Carla Zangari de Souza, Suelen Santos da Silva, Bruna Tiaki Tiyo, Fernanda F Evangelista, Lourenco Higa, Ivete Conchon-Costa, Ana Lúcia Falavigna-Guilherme
This study detected and compared the levels of IFN-γ, TNF-α, TGF-β and nitric oxide (NO) in amniotic fluid (AF) and serum of pregnancies with acute toxoplasmosis, Southern Brazil. It also was compared the levels of the same mediators in the serum of pregnancies in acute and chronic toxoplasmosis with non-infected. Serological investigation, anti-T gondii IgM and IgG, of the 67 pregnancies was determined by Elisa MEIA. Forty two were uninfected, eight in chronic phase and 17 in acute phase. Among the acute phase, seven agreed to amniocentesis...
March 13, 2018: Cytokine
https://www.readbyqxmd.com/read/29493778/effects-of-betamethasone-on-fetoplacental-and-maternal-hemodynamics-in-preterm-pregnancies
#6
Cihan Inan, N Cenk Sayin, Zehra N Dolgun, Selen G Erzincan, Isil Uzun, Havva Sutcu, Necdet Sut, Fusun G Varol
OBJECTIVE: To evaluate the possible effects of prenatal steroid administration on Doppler parameters of the umbilical artery, uterine artery, middle cerebral artery, and ductus venosus, the cerebroplacental ratio, and the amniotic fluid index in preterm fetuses. METHODS: The present prospective observational study was performed at the Perinatology Department of Trakya University, Edirne, Turkey, between June 1, 2015, and September 1, 2016. It included patients with healthy singleton pregnancies who had received betamethasone at 24-34 weeks of pregnancy...
March 1, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29478363/fetal-biacromial-diameter-as-a-new-ultrasound-measure-for-prediction-of-macrosomia-in-term-pregnancy-a-prospective-observational-study
#7
Alaa Eldin A Youssef, Ahmed F Amin, Mohamed Khalaf, Marwa S Khalaf, Mohammed K Ali, Ahmed M Abbas
OBJECTIVE: The current study aims to evaluate a simple method for sonographic measurement of the fetal biacromial diameter for prediction of fetal macrosomia in term pregnancy. MATERIALS AND METHODS: The current study was a single center prospective observational study conducted in a tertiary University Hospital from January 2015 to May 2017. We included all consecutive term (37-42 weeks) pregnant women presented to the labor ward for delivery. Ultrasound parameters were measured as biparietal diameter, head circumference, transverse thoracic diameter, mid arm diameter, abdominal circumference, femur length, estimated fetal weight and amniotic fluid index...
February 25, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29414511/human-plasma-retinol-binding-protein-rbp4-is-also-a-fatty-acid-binding-protein
#8
Massimiliano Perduca, Stefania Nicolis, Barbara Mannucci, Monica Galliano, Hugo L Monaco
RBP4 (plasma retinol-binding protein) is the 21 kDa transporter of all-trans retinol that circulates in plasma as a moderately tight 1:1 molar complex of the vitamin with the protein. RBP4 is primarily synthesized in the liver but is also produced by adipose tissue and circulates bound to a larger protein, transthyretin, TTR, that serves to increase its molecular mass and thus avoid its elimination by glomerular filtration. This paper reports the high resolution three-dimensional structures of human RBP4 naturally lacking bound retinol purified from plasma, urine and amniotic fluid...
January 31, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29410259/estimated-versus-measured-blood-loss-during-dilation-and-evacuation-an-observational-study
#9
Elissa T Serapio, Geffan A Pearlson, Eleanor A Drey, Jennifer L Kerns
OBJECTIVE: To compare estimated versus measured blood loss at the time of dilation and evacuation (D&E). STUDY DESIGN: We measured blood loss for all D&E procedures between 16-24weeks at one abortion clinic over nine months. We weighed all blood-containing items and measured blood captured in the D&E tray. Providers recorded estimated blood loss before weighing or measuring blood. We compared median measured blood loss (MBL) and estimated blood loss (EBL) for each gestational week...
February 1, 2018: Contraception
https://www.readbyqxmd.com/read/29393671/importance-of-maternal-diet-in-the-training-of-the-infant-s-immune-system-during-gestation-and-lactation
#10
P V Jeurink, K Knipping, F Wiens, K Barańska, B Stahl, J Garssen, B Krolak-Olejnik
Latest forecasts predict that half of the European population will be allergic within the coming 15 years, with food allergies contributing substantially to the total burden; preventive measures are urgently needed. Unfortunately, all attempted alimentary strategies for primary prevention of allergic diseases through allergen avoidance so far have failed. This also holds true for the prevention of food allergies in breastfed infants by the common practice of excluding certain foods with allergenic potential from the maternal diet...
February 2, 2018: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29393249/upregulation-of-vascular-endothelial-growth-factor-in-amniotic-fluid-stem-cells-enhances-their-potential-to-attenuate-lung-injury-in-a-preterm-rabbit-model-of-bronchopulmonary-dysplasia
#11
Julio Jiménez, Flore Lesage, Jute Richter, Taro Nagatomo, Thomas Salaets, Silvia Zia, Marina Gabriela Mori Da Cunha, Jeroen Vanoirbeek, Jan A Deprest, Jaan Toelen
BACKGROUND: Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects extremely preterm infants and remains - despite improvements in neonatal intensive care - a major cause of neonatal mortality and morbidity. Cell-therapeutic strategies employing mesenchymal stem cells (MSC) have been shown to modulate lung development in BPD models. OBJECTIVE: Herein, we evaluate the potential of human amniotic fluid (hAF)-SC and hAF-SC with upregulated expression of vascular endothelial growth factor (VEGF) as cell-therapeutic agents for BPD...
2018: Neonatology
https://www.readbyqxmd.com/read/29381473/low-dose-aspirin-for-preventing-fetal-growth-restriction-a-randomised-trial
#12
Anca-Daniela Stanescu, Roxana Banica, Romina-Marina Sima, Liana Ples
The purpose of this study was to investigate when in pregnancy to stop the administration of low dose aspirin (150 mg/daily) so as to prevent fetal growth restriction (FGR) A randomised, placebo-controlled study was designed. The patients were all screened positive using the Fetal Medicine Foundation (FMF) early pregnancy screening test for preeclampsia (PE) and FGR prediction. One hundred and fifty patients were enrolled and divided equally into three groups: A - the controls who received placebo treatment; B - those who received aspirin till 32 weeks of gestation and C - those who received aspirin till 36 weeks of gestation...
January 30, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29357925/intra-amniotic-inflammation-and-child-neurodevelopment-a-systematic-review-protocol
#13
Laurence Soucy-Giguère, Cédric Gasse, Yves Giguère, Suzanne Demers, Emmanuel Bujold, Amélie Boutin
BACKGROUND: Intra-amniotic inflammation is associated with adverse pregnancy and neonatal outcomes. However, the impact on child neurodevelopment remains unclear. We aim to assess the effect of intra-amniotic inflammation on neurodevelopmental outcomes in children. METHODS: The databases MEDLINE, Embase, CINAHL, and Cochrane will be searched from their inception until November 2017. Randomized trials and cohort studies in which inflammatory markers were measured in amniotic fluid collected by amniocentesis and in which infant's neurodevelopment was assessed will be eligible...
January 22, 2018: Systematic Reviews
https://www.readbyqxmd.com/read/29357727/amniotic-fluid-hif1%C3%AE-and-exosomal-hif1%C3%AE-in-cervical-insufficiency-patients-with-physical-examination-indicated-cerclage
#14
Ji Eun Song, Seok Ju Park, Keun Young Lee, Wang Jae Lee
OBJECTIVE: Hypoxia inducible factor 1α (HIF1α) has been reported to activate inflammatory cascade. Recently, exosomes have been known to have pivotal roles in intercellular communication. The aim of this study was to compare the concentration of amniotic fluid (AF) HIF1α, exosomal HIF1α, and inflammatory cytokines such as interleukin 1α (IL1α), interleukin 1β (IL1β), interleukin 6 (IL6), and tumor necrosis factor α (TNFα) between physical examination-indicated cerclage (PEIC) and control group...
January 22, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29347926/handheld-ultrasound-to-avert-maternal-and-neonatal-deaths-in-2-regions-of-the-philippines-an-ibuntis%C3%A2-intervention-study
#15
Godofreda V Dalmacion, Ramon T Reyles, Antonia E Habana, Lalaine Mae V Cruz, Maricelle C Chua, Analyn T Ngo, Milagros J Tia-Jocson, Emmanuel S Baja
BACKGROUND: The major causes of maternal and neonatal mortality in the Philippines are hemorrhages and obstructed labor due to placental implantation abnormalities (PIAs), twin pregnancies and fetal malpresentations. All of which are all easily detected by ultrasound. However, women in rural areas and low-income groups do not have access to ultrasound during their prenatal care. We aimed to provide additional evidence on the benefits of handheld ultrasound (HU) for screening pregnancy related abnormalities in order to avert maternal and neonatal deaths...
January 18, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29346438/colonization-of-the-cervicovaginal-space-with-gardnerella-vaginalis-leads-to-local-inflammation-and-cervical-remodeling-in-pregnant-mice
#16
Luz-Jeannette Sierra, Amy G Brown, Guillermo O Barilá, Lauren Anton, Carrie E Barnum, Snehal S Shetye, Louis J Soslowsky, Michal A Elovitz
The role of the cervicovaginal (CV) microbiome in regulating cervical function during pregnancy is poorly understood. Gardnerella vaginalis (G. vaginalis) is the most common bacteria associated with the diagnosis of bacterial vaginosis (BV). While BV has been associated with preterm birth (PTB), clinical trials targeting BV do not decrease PTB rates. It remains unknown if G. vaginalis is capable of triggering molecular, biomechanical and cellular events that could lead to PTB. The objective of this study was to determine if cervicovaginal colonization with G...
2018: PloS One
https://www.readbyqxmd.com/read/29327361/myocardial-injury-in-fetal-aortic-stenosis-insights-from-amniotic-fluid-analysis
#17
Kevin G Friedman, Lynn A Sleeper, Raina N Fichorova, Taylor Weilnau, Wayne Tworetzky, Louise E Wilkins-Haug
OBJECTIVE: Fetal aortic stenosis (AS) imposes pressure load on the developing left ventricle (LV) and leads to derangements in myocardial structure and function via mechanisms that are not well characterized. METHODS: We compared amniotic fluid NT-BNP and troponin levels in fetuses with AS prior to fetal valvuloplasty and controls. We estimated correlations between NT-BNP and fetal echo parameters and identify NT-BNP cutoff associated with biventricular outcome RESULTS: Median NT-BNP level was higher in fetal AS than controls (3858 vs 1737 pg/mL, P < 0...
February 2018: Prenatal Diagnosis
https://www.readbyqxmd.com/read/29318985/a-randomised-controlled-trial-and-economic-evaluation-of-intraoperative-cell-salvage-during-caesarean-section-in-women-at-risk-of-haemorrhage-the-salvo-cell-salvage-in-obstetrics-trial
#18
Khalid S Khan, Philip Moore, Matthew Wilson, Richard Hooper, Shubha Allard, Ian Wrench, Tracy Roberts, Carol McLoughlin, Lee Beresford, James Geoghegan, Jane Daniels, Sue Catling, Vicki A Clark, Paul Ayuk, Stephen Robson, Fang Gao-Smith, Matthew Hogg, Louise Jackson, Doris Lanz, Julie Dodds
BACKGROUND: Caesarean section is associated with blood loss and maternal morbidity. Excessive blood loss requires transfusion of donor (allogeneic) blood, which is a finite resource. Cell salvage returns blood lost during surgery to the mother. It may avoid the need for donor blood transfusion, but reliable evidence of its effects is lacking. OBJECTIVES: To determine if routine use of cell salvage during caesarean section in mothers at risk of haemorrhage reduces the rates of blood transfusion and postpartum maternal morbidity, and is cost-effective, in comparison with standard practice without routine salvage use...
January 2018: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29316210/fate-of-egg-proteins-during-the-development-of-columba-livia-domestica-embryo
#19
Seba Jamal Shbailat, Ibtisam Omar Aslan
The transfer of egg white into the yolk and consumption of yolk proteins by the embryo are largely unexplored in the pigeon Columba livia domestica. Here, we investigated the route of egg white transfer as well as the degradation and uptake of yolk proteins by the pigeon embryo. Initially, we tested the electrophoretic patterns of proteins in different egg compartments throughout development. Then, we used lysozyme as a reference protein to follow the egg white transfer, and we measured its activity using Micrococcus lysodeikticus as a substrate...
January 2018: Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution
https://www.readbyqxmd.com/read/29288189/the-renal-parenchyma-evaluation-of-a-novel-ultrasound-measurement-to-assess-fetal-renal-development-protocol-for-an-observational-longitudinal-study
#20
Sonja Brennan, Michal Schneider, David Watson, Yogavijayan Kandasamy, Donna Rudd
INTRODUCTION: Disorders of fetal growth, such as intrauterine growth restriction (IUGR) and large for gestational age (LGA), have been found to have a profound effect on the development of the fetal kidney. Abnormal kidney development is associated with hypertension and chronic kidney disease later in life. This study will use a novel ultrasound measurement to assess the renal parenchymal growth and kidney arterial blood flow in the fetus to evaluate the development of the fetal kidneys and provide an indirect estimate of nephron number...
December 28, 2017: BMJ Open
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