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amniotic fluid measurements

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https://www.readbyqxmd.com/read/29232399/maternal-white-blood-cell-count-cannot-identify-the-presence-of-microbial-invasion-of-the-amniotic-cavity-or-intra-amniotic-inflammation-in-women-with-preterm-prelabor-rupture-of-membranes
#1
Ivana Musilova, Lenka Pliskova, Romana Gerychova, Petr Janku, Ondrej Simetka, Petr Matlak, Bo Jacobsson, Marian Kacerovsky
OBJECTIVE: The main aim of this study was to determine the relationship between the maternal white blood cell (WBC) count at the time of hospital admission in pregnancies complicated by preterm prelabor rupture of membranes (PPROM) and the presence of microbial invasion of the amniotic cavity (MIAC) and/or intra-amniotic inflammation (IAI). The second aim was to test WBC diagnostic indices with respect to the presence of MIAC and/or IAI. METHODS: Four hundred and seventy-nine women with singleton pregnancies complicated by PPROM, between February 2012 and June 2017, were included in this study...
2017: PloS One
https://www.readbyqxmd.com/read/29219113/diagnostic-role-of-microrna-expression-profile-in-the-prenatal-amniotic-fluid-samples-of-pregnant-women-with-down-syndrome
#2
Emin Karaca, Ayça Aykut, Biray Ertürk, Burak Durmaz, Ahmet Güler, Barış Büke, Ahmet Özgür Yeniel, Ahmet Mete Ergenoğlu, Ferda Özkınay, Mehmet Özeren, Mert Kazandı, Fuat Akercan, Sermet Sağol, Cumhur Gündüz, Özgür Çoğulu
BACKGROUND: Down syndrome is the most common chromosomal anomaly in humans. Down syndrome is the most common chromosomal anomaly in humans affecting people from every race and age. Most of the cases are can be diagnosed by prenatal diagnostic methods in pregnancy. Due to the longtime of culture method applied for prenatal diagnosis, genetic analysis has been developed and developing for rapid diagnosis. For this reason, the effective use of miRNAs was investigated in the rapid analysis of prenatal samples with Down syndrome...
December 8, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/29210307/amniotic-fluid-oxidant-antioxidant-status-in-foetal-congenital-nervous-system-anomalies
#3
Numan Cim, Harun Egemen Tolunay, Erbil Karaman, Barıs Boza, Mustafa Bilici, Orkun Çetin, Recep Yıldızhan, Hanım Guler Sahin
Objective This study aimed to evaluate the oxidant-antioxidant status of amniotic fluid in pregnant women with foetal congenital malformations of the central nervous system. Methods We studied pregnant women with foetal congenital nervous system anomalies at 16-22 weeks' gestation (n = 36). The control group (n = 30) consisted of pregnant women at the same gestational age who underwent amniocentesis, resulting in a normal karyotype. We analysed glutathione, catalase, and malondialdehyde levels in amniotic fluid...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/29195161/prenatal-and-pubertal-testosterone-affect-brain-lateralization
#4
T Beking, R H Geuze, M van Faassen, I P Kema, B P C Kreukels, T G G Groothuis
After decades of research, the influence of prenatal testosterone on brain lateralization is still elusive, whereas the influence of pubertal testosterone on functional brain lateralization has not been investigated, although there is increasing evidence that testosterone affects the brain in puberty. We performed a longitudinal study, investigating the relationship between prenatal testosterone concentrations in amniotic fluid, pubertal testosterone concentrations in saliva, and brain lateralization (measured with functional Transcranial Doppler ultrasonography (fTCD)) of the Mental Rotation, Chimeric Faces and Word Generation tasks...
November 6, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29173937/relationship-between-ultrasonic-marker-of-fetal-lung-maturity-and-lamellar-body-count
#5
Khadije Rezaie Keikhaie, Kolsoum Rezaie Kahkhaie, Nooshin Mohammadi, Nooshin Amjadi, Aliye Ahmadi Forg, Abbas Ali Ramazani
BACKGROUND: The aim of this study was prediction the fetal lung maturity by ultrasonic markers and comparison by lamellar body count and fetal outcome. METHODS: A prospective Longitudinal study Department of perinatology of performed Emam Khomeini hospital and Mirza Kochak Khan Hospital in Tehran, Iran from March 2013 to January 2014. 100 pregnant women (37-40 weeks of gestation) who were admitted for elective cesarean section and referred for an obstetric ultrasound scan at the same day of their elective cesarean section were included...
January 2017: Journal of the National Medical Association
https://www.readbyqxmd.com/read/29155162/chorioamnionitis-due-to-leptotrichia-trevisanii
#6
Dionisia Fontanals, Carlos García-Miralles, Rosa Ballester, Belen Cochs, Ruth Orellana, Sílvia Capilla
Very long fusiform gram-negative bacilli were observed after Gram staining of amniotic fluid from a 36-year-old multigravida woman. At 24 hours, pure, abundant growth of smooth, gray, only slightly convex catalase-positive and oxidase-negative colonies measuring about 2 mm were observed. Growth was greater in anaerobic than in aerobic conditions. The bacterium was identified as Leptotrichia trevisanii by matrix-assisted laser desorption ionization time of flight mass spectrometry. Ampicillin and gentamicin were prescribed for chorioamnionitis, and vaginal prostaglandins were administered to terminate the pregnancy...
November 15, 2017: Anaerobe
https://www.readbyqxmd.com/read/29141467/oxidative-stress-biomarkers-in-amniotic-fluid-of-pregnant-women-with-hypothyroidism
#7
Tanja R Novakovic, Zana C Dolicanin, Natasa Z Djordjevic
PURPOSE: Hypothyroidism in pregnancy is the serious state that may lead to fetal morbidity and mortality. Oxidative stress biomarkers in the amniotic fluid can provide important information on the health, development and maturation of the fetus during pregnancy. In this study, we examined whether maternal hypothyroidism contributes to increased oxidative stress biomarkers in the amniotic fluid during the first trimester of pregnancy. MATERIALS AND METHODS: The study was conducted on healthy pregnant women and pregnant women with hypothyroidism (gestational age: 16-18 weeks)...
November 15, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29129159/third-trimester-ultrasound-accuracy-and-delivery-outcome-in-obese-and-morbid-obese-pregnant-women
#8
Sawsan Al-Obaidly, Abdullah Al-Ibrahim, Najah Saleh, Mariam Al-Belushi, Zeena Al-Mansouri, Najat Khenyab
OBJECTIVE: Several studies have highlighted the negative impact of maternal obesity on ultrasound accuracy for fetal weight estimation (EFW). However, the evidence is conflicting. We aimed in our study to find if the ultrasound accuracy for EFW would differ or decrease in obese and morbid obesity classes. We also studied the mode of delivery within the same cohort. METHODS: It is a retrospective study of obese patients with recorded BMI ≥30 kg/m2, class I and II (BMI: 30-39...
November 22, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29111618/toxic-metals-in-amniotic-fluid-and-altered-gene-expression-in-cell-free-fetal-rna
#9
Lisa Smeester, Elizabeth M Martin, Pete Cable, Wanda Bodnar, Kim Boggess, Neeta L Vora, Rebecca C Fry
Both exposure to toxic metals, as well as deficiencies in essential metals, during pregnancy has been linked to a variety of negative reproductive outcomes. The exact etiologies of such outcomes and the effects of fetal exposure to these metals are largely unknown. Therefore, the ability to assess levels of these elements is critical to determining the underlying causes of such conditions and the effects that both essential and non-essential metals have in fetal development. Thus, using cell-free fetal RNA (cffRNA) from amniotic fluid, we set out to measure the association between amniotic fluid levels of toxic and essential metals and fetal gene expression...
November 7, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/29100749/presence-of-benzophenones-commonly-used-as-uv-filters-and-absorbers-in-paired-maternal-and-fetal-samples
#10
M Krause, H Frederiksen, K Sundberg, F S Jørgensen, L N Jensen, P Nørgaard, C Jørgensen, P Ertberg, A Juul, K T Drzewiecki, N E Skakkebaek, A M Andersson
BACKGROUND: Previous studies have demonstrated widespread exposure of humans to certain benzophenones commonly used as UV filters or UV absorbers; some of which have been demonstrated to have endocrine disrupting abilities. OBJECTIVES: To examine whether benzophenones present in pregnant women pass through the placental barrier to amniotic fluid and further to the fetal blood circulation. METHODS: A prospective study of 200 pregnant women with simultaneously collected paired samples of amniotic fluid and maternal serum and urine...
January 2018: Environment International
https://www.readbyqxmd.com/read/29077950/effects-of-in-ovo-feeding-of-cationic-amino-acids-on-hatchability-hatch-weights-and-organ-developments-in-domestic-pigeon-squabs-columba-livia
#11
X Y Zhang, L L Li, L P Miao, N N Zhang, X T Zou
This study was conducted to evaluate the effect of in ovo feeding of cationic amino acids on hatchability, hatch weights, and organ developments in pigeon squabs. Two experiments were conducted in this study. Eggs in Exp. 1 were subjected to modification of in ovo feeding in pigeons. Optimal time was determined by checking amniotic fluid volume, and suitable length was confirmed through ink injection. Results showed that the optimum time of in ovo feeding was on d 13 of embryonic development, and the suitable injected length was 20 mm to reach the amniotic cavity of the embryo...
October 25, 2017: Poultry Science
https://www.readbyqxmd.com/read/29030170/in-utero-negativization-of-zika-virus-in-a-case-with-serious-central-nervous-system-abnormalities
#12
Carlota Rodó, Anna Suy, Elena Sulleiro, Antoni Soriano-Arandes, Andrés Antón, Itziar García, Silvia Arévalo, Élida Vázquez, Ana Vázquez, Fernando de Ory, M Paz Sánchez-Seco, Carlos Rodrigo, Tomás Pumarola, Elena Carreras
OBJECTIVES: To describe a case of a pregnant woman with Zika virus infection and severe fetal brain malformations. METHODS: Serial ultrasound measurements, fetal magnetic resonance imaging results, laboratory and amniocentesis results, and perinatal outcomes of the pregnant woman and her neonate are reported. RESULTS: Zika virus tested positive in amniotic fluid at 19 weeks while being negative at delivery. The newborn did not meet the case definition of congenital Zika virus syndrome because neither the Zika virus RNA nor immunoglobulin M antibodies were detected; however, prenatal brain lesions were confirmed after birth...
October 10, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29016591/caesarean-section-during-second-stage-of-labor-in-a-tertiary-centre
#13
Padma Gurung, Sameer Malla, Sushma Lama, Anagha Malla, Alka Singh
BACKGROUND: There is an alarming rise in caesarean section leading to increased adverse outcomes for both the mother and fetus when compared with vaginal delivery. Within this increasing caesarean section rate, there is a concerning increase in the rate of second stage caesarean section. This study highlight the feto-maternal outcome of caesarean section in second stage of labour. METHODS: This was a retrospective cohort review of all women with a singleton, cephalic fetus at term delivered by caesarean section in the second stage of labor between April 1, 2013 and March 30, 2017 at Patan Academy of Health Sciences...
September 8, 2017: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/28965779/pregnancy-exposure-to-quetiapine-therapeutic-drug-monitoring-in-maternal-blood-amniotic-fluid-and-cord-blood-and-obstetrical-outcomes
#14
Michael Paulzen, Tamme W Goecke, Maxim Kuzin, Marc Augustin, Gerhard Gründer, Georgios Schoretsanitis
RATIONALE: This prospective study is the first to measure and correlate quetiapine concentrations in maternal blood, amniotic fluid and umbilical cord blood to account for the distribution of quetiapine. METHODS: Concentrations of quetiapine are quantified in seven mother infant pairs at the time of delivery. Data are provided as median values, first (Q1) and third (Q3) quartiles and ranges. To account for the penetration ratio, the concentration of quetiapine in amniotic fluid and cord blood was divided by maternal concentrations...
September 28, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28873045/gadolinium-chelate-safety-in-pregnancy-barely-detectable-gadolinium-levels-in-the-juvenile-nonhuman-primate-after-in-utero-exposure
#15
Joao Prola-Netto, Mark Woods, Victoria H J Roberts, Elinor L Sullivan, Christina Ann Miller, Antonio E Frias, Karen Y Oh
Purpose To determine whether gadolinium remains in juvenile nonhuman primate tissue after maternal exposure to intravenous gadoteridol during pregnancy. Materials and Methods Gravid rhesus macaques and their offspring (n = 10) were maintained, as approved by the institutional animal care and utilization committee. They were prospectively studied as part of a pre-existing ongoing research protocol to evaluate the effects of maternal malnutrition on placental and fetal development. On gestational days 85 and 135, they underwent placental magnetic resonance imaging after intravenous gadoteridol administration...
September 4, 2017: Radiology
https://www.readbyqxmd.com/read/28851489/interfacial-tensiometry-and-dilational-surface-visco-elasticity-of-biological-liquids-in-medicine
#16
REVIEW
V B Fainerman, D V Trukhin, Igor I Zinkovych, R Miller
Dynamic surface tensions and dilational visco-elasticity are easy accessible parameters of liquids. For human body liquids, such as urine, blood serum, amniotic fluid, gastric juice, saliva and others, these parameters are very characteristic for the health status of people. In case of a disease the composition of certain liquids specifically changes and the measured characteristics of dynamic surface tension of the dilational surface elasticity and viscosity reflect these changes in a clear way. Thus, this kind of physico-chemical measurements represent sensitive tools for evaluating the severity of a disease and can serve as control tool for the efficiency of applied therapies...
August 10, 2017: Advances in Colloid and Interface Science
https://www.readbyqxmd.com/read/28844799/exposure-to-benzophenone-3-and-reproductive-toxicity-a-systematic-review-of-human-and-animal-studies
#17
REVIEW
Marya Ghazipura, Richard McGowan, Alan Arslan, Tanzib Hossain
Hydroxy-4-methoxybenzophenone, also known as benzophenone-3 (BP-3), is a commonly used ultraviolet filter in skincare and as a food additive. Large concentrations of similar phenolic compounds have been detected in urine, amniotic fluid, and placental tissue, thereby raising questions about its impact on reproduction. The objective of this paper was to investigate the reproductive toxicity of BP-3 in humans and animals. In humans, studies showed that high levels of BP-3 exposure could be linked to an increase in male birth weight but a decline in female birth weight and male gestational age...
August 24, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28813455/maternal-serum-c-reactive-protein-concentration-and-intra-amniotic-inflammation-in-women-with-preterm-prelabor-rupture-of-membranes
#18
Ivana Musilova, Marian Kacerovsky, Martin Stepan, Tomas Bestvina, Lenka Pliskova, Barbora Zednikova, Bo Jacobsson
OBJECTIVE: To evaluate maternal serum C-reactive protein (CRP) concentrations in pregnancies complicated by preterm prelabor rupture of membranes (PPROM) in relation to the presence of microbial invasion of the amniotic cavity (MIAC) and/or intra-amniotic inflammation (IAI). METHODS: Two hundred and eighty-seven women with singleton pregnancies complicated by PPROM between 2014 and 2016 were included in this study. Maternal blood and amniotic fluid samples were collected at the time of admission...
2017: PloS One
https://www.readbyqxmd.com/read/28805615/prenatal-diagnosis-of-holoprosencephaly-associated-with-smith-lemli-opitz-syndrome-slos-in-a-46-xx-fetus
#19
André Travessa, Patrícia Dias, Pedro Rocha, Ana Berta Sousa
OBJECTIVE: To show the importance of measuring cholesterol precursor levels in amniotic fluid in all pregnancies with ultrasound features (such as holoprosencephaly) suggestive of Smith-Lemli-Opitz syndrome (SLOS), after exclusion of chromosomal anomalies. CASE REPORT: A 28-year-old woman, gravida 1 para 0, performed chorionic villus sampling for fetal karyotyping at 13 weeks of gestation due to positive combined first trimester screening in a fetus with increased nuchal translucency and suspected holoprosencephaly...
August 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28805106/measuring-fetal-brain-and-lung-transcripts-in-amniotic-fluid-supernatant-a-comparison-of-digital-pcr-and-rt-qpcr-methods
#20
Lisa Hui, Sally Beard, Natalie J Hannan
PURPOSE: Amniotic fluid (AF) cell-free RNA is a promising source of information regarding fetal physiology. Digital PCR (dPCR) is a direct approach to nucleic acid detection that reports absolute transcript copy number. The aim of this study was to compare quantification of cell-free fetal brain and lung RNA transcripts in AF by reverse transcription-qPCR (RT-qPCR) and dPCR. MATERIAL AND METHODS: Prospective hospital-based study was performed in 2016-2017. Pulmonary genes were quantified in term AF samples collected at elective cesarean birth; neurodevelopmental genes were measured in preterm samples (<34 weeks) obtained from women undergoing clinically-indicated amniocentesis...
August 24, 2017: Journal of Maternal-fetal & Neonatal Medicine
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