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amniotic fluid measurements

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https://www.readbyqxmd.com/read/29414511/human-plasma-retinol-binding-protein-rbp4-is-also-a-fatty-acid-binding-protein
#1
Massimiliano Perduca, Stefania Nicolis, Barbara Mannucci, Monica Galliano, Hugo L Monaco
RBP4 (plasma retinol-binding protein) is the 21 kDa transporter of all-trans retinol that circulates in plasma as a moderately tight 1:1 molar complex of the vitamin with the protein. RBP4 is primarily synthesized in the liver but is also produced by adipose tissue and circulates bound to a larger protein, transthyretin, TTR, that serves to increase its molecular mass and thus avoid its elimination by glomerular filtration. This paper reports the high resolution three-dimensional structures of human RBP4 naturally lacking bound retinol purified from plasma, urine and amniotic fluid...
January 31, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29410259/estimated-versus-measured-blood-loss-during-dilation-and-evacuation-an-observational-study
#2
Elissa T Serapio, Geffan A Pearlson, Eleanor A Drey, Jennifer L Kerns
OBJECTIVE: To compare estimated versus measured blood loss at the time of dilation and evacuation (D&E). STUDY DESIGN: We measured blood loss for all D&E procedures between 16-24weeks at one abortion clinic over nine months. We weighed all blood-containing items and measured blood captured in the D&E tray. Providers recorded estimated blood loss before weighing or measuring blood. We compared median measured blood loss (MBL) and estimated blood loss (EBL) for each gestational week...
February 1, 2018: Contraception
https://www.readbyqxmd.com/read/29393671/importance-of-maternal-diet-in-the-training-of-the-infant-s-immune-system-during-gestation-and-lactation
#3
P V Jeurink, K Knipping, F Wiens, K Barańska, B Stahl, J Garssen, B Krolak-Olejnik
Latest forecasts predict that half of the European population will be allergic within the coming 15 years, with food allergies contributing substantially to the total burden; preventive measures are urgently needed. Unfortunately, all attempted alimentary strategies for primary prevention of allergic diseases through allergen avoidance so far have failed. This also holds true for the prevention of food allergies in breastfed infants by the common practice of excluding certain foods with allergenic potential from the maternal diet...
February 2, 2018: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29393249/upregulation-of-vascular-endothelial-growth-factor-in-amniotic-fluid-stem-cells-enhances-their-potential-to-attenuate-lung-injury-in-a-preterm-rabbit-model-of-bronchopulmonary-dysplasia
#4
Julio Jiménez, Flore Lesage, Jute Richter, Taro Nagatomo, Thomas Salaets, Silvia Zia, Marina Gabriela Mori Da Cunha, Jeroen Vanoirbeek, Jan A Deprest, Jaan Toelen
BACKGROUND: Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects extremely preterm infants and remains - despite improvements in neonatal intensive care - a major cause of neonatal mortality and morbidity. Cell-therapeutic strategies employing mesenchymal stem cells (MSC) have been shown to modulate lung development in BPD models. OBJECTIVE: Herein, we evaluate the potential of human amniotic fluid (hAF)-SC and hAF-SC with upregulated expression of vascular endothelial growth factor (VEGF) as cell-therapeutic agents for BPD...
February 1, 2018: Neonatology
https://www.readbyqxmd.com/read/29381473/low-dose-aspirin-for-preventing-fetal-growth-restriction-a-randomised-trial
#5
Anca-Daniela Stanescu, Roxana Banica, Romina-Marina Sima, Liana Ples
The purpose of this study was to investigate when in pregnancy to stop the administration of low dose aspirin (150 mg/daily) so as to prevent fetal growth restriction (FGR) A randomised, placebo-controlled study was designed. The patients were all screened positive using the Fetal Medicine Foundation (FMF) early pregnancy screening test for preeclampsia (PE) and FGR prediction. One hundred and fifty patients were enrolled and divided equally into three groups: A - the controls who received placebo treatment; B - those who received aspirin till 32 weeks of gestation and C - those who received aspirin till 36 weeks of gestation...
January 30, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29357925/intra-amniotic-inflammation-and-child-neurodevelopment-a-systematic-review-protocol
#6
Laurence Soucy-Giguère, Cédric Gasse, Yves Giguère, Suzanne Demers, Emmanuel Bujold, Amélie Boutin
BACKGROUND: Intra-amniotic inflammation is associated with adverse pregnancy and neonatal outcomes. However, the impact on child neurodevelopment remains unclear. We aim to assess the effect of intra-amniotic inflammation on neurodevelopmental outcomes in children. METHODS: The databases MEDLINE, Embase, CINAHL, and Cochrane will be searched from their inception until November 2017. Randomized trials and cohort studies in which inflammatory markers were measured in amniotic fluid collected by amniocentesis and in which infant's neurodevelopment was assessed will be eligible...
January 22, 2018: Systematic Reviews
https://www.readbyqxmd.com/read/29357727/amniotic-fluid-hif1%C3%AE-and-exosomal-hif1%C3%AE-in-cervical-insufficiency-patients-with-physical-examination-indicated-cerclage
#7
Ji Eun Song, Seok Ju Park, Keun Young Lee, Wang Jae Lee
OBJECTIVE: Hypoxia inducible factor 1α (HIF1α) has been reported to activate inflammatory cascade. Recently, exosomes have been known to have pivotal roles in intercellular communication. The aim of this study was to compare the concentration of amniotic fluid (AF) HIF1α, exosomal HIF1α, and inflammatory cytokines such as interleukin 1α (IL1α), interleukin 1β (IL1β), interleukin 6 (IL6), and tumor necrosis factor α (TNFα) between physical examination-indicated cerclage (PEIC) and control group...
January 22, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29347926/handheld-ultrasound-to-avert-maternal-and-neonatal-deaths-in-2-regions-of-the-philippines-an-ibuntis%C3%A2-intervention-study
#8
Godofreda V Dalmacion, Ramon T Reyles, Antonia E Habana, Lalaine Mae V Cruz, Maricelle C Chua, Analyn T Ngo, Milagros J Tia-Jocson, Emmanuel S Baja
BACKGROUND: The major causes of maternal and neonatal mortality in the Philippines are hemorrhages and obstructed labor due to placental implantation abnormalities (PIAs), twin pregnancies and fetal malpresentations. All of which are all easily detected by ultrasound. However, women in rural areas and low-income groups do not have access to ultrasound during their prenatal care. We aimed to provide additional evidence on the benefits of handheld ultrasound (HU) for screening pregnancy related abnormalities in order to avert maternal and neonatal deaths...
January 18, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29346438/colonization-of-the-cervicovaginal-space-with-gardnerella-vaginalis-leads-to-local-inflammation-and-cervical-remodeling-in-pregnant-mice
#9
Luz-Jeannette Sierra, Amy G Brown, Guillermo O Barilá, Lauren Anton, Carrie E Barnum, Snehal S Shetye, Louis J Soslowsky, Michal A Elovitz
The role of the cervicovaginal (CV) microbiome in regulating cervical function during pregnancy is poorly understood. Gardnerella vaginalis (G. vaginalis) is the most common bacteria associated with the diagnosis of bacterial vaginosis (BV). While BV has been associated with preterm birth (PTB), clinical trials targeting BV do not decrease PTB rates. It remains unknown if G. vaginalis is capable of triggering molecular, biomechanical and cellular events that could lead to PTB. The objective of this study was to determine if cervicovaginal colonization with G...
2018: PloS One
https://www.readbyqxmd.com/read/29327361/myocardial-injury-in-fetal-aortic-stenosis-insights-from-amniotic-fluid-analysis
#10
Kevin G Friedman, Lynn A Sleeper, Raina N Fichorova, Taylor Weilnau, Wayne Tworetzky, Louise E Wilkins-Haug
OBJECTIVE: Fetal aortic stenosis (AS) imposes pressure load on the developing left ventricle (LV) and leads to derangements in myocardial structure and function via mechanisms that are not well characterized. METHODS: We compared amniotic fluid NT-BNP and troponin levels in fetuses with AS prior to fetal valvuloplasty and controls. We estimated correlations between NT-BNP and fetal echo parameters and identify NT-BNP cutoff associated with biventricular outcome RESULTS: Median NT-BNP level was higher in fetal AS than controls (3858 vs 1737 pg/mL, P < 0...
January 11, 2018: Prenatal Diagnosis
https://www.readbyqxmd.com/read/29318985/a-randomised-controlled-trial-and-economic-evaluation-of-intraoperative-cell-salvage-during-caesarean-section-in-women-at-risk-of-haemorrhage-the-salvo-cell-salvage-in-obstetrics-trial
#11
Khalid S Khan, Philip Moore, Matthew Wilson, Richard Hooper, Shubha Allard, Ian Wrench, Tracy Roberts, Carol McLoughlin, Lee Beresford, James Geoghegan, Jane Daniels, Sue Catling, Vicki A Clark, Paul Ayuk, Stephen Robson, Fang Gao-Smith, Matthew Hogg, Louise Jackson, Doris Lanz, Julie Dodds
BACKGROUND: Caesarean section is associated with blood loss and maternal morbidity. Excessive blood loss requires transfusion of donor (allogeneic) blood, which is a finite resource. Cell salvage returns blood lost during surgery to the mother. It may avoid the need for donor blood transfusion, but reliable evidence of its effects is lacking. OBJECTIVES: To determine if routine use of cell salvage during caesarean section in mothers at risk of haemorrhage reduces the rates of blood transfusion and postpartum maternal morbidity, and is cost-effective, in comparison with standard practice without routine salvage use...
January 2018: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29316210/fate-of-egg-proteins-during-the-development-of-columba-livia-domestica-embryo
#12
Seba Jamal Shbailat, Ibtisam Omar Aslan
The transfer of egg white into the yolk and consumption of yolk proteins by the embryo are largely unexplored in the pigeon Columba livia domestica. Here, we investigated the route of egg white transfer as well as the degradation and uptake of yolk proteins by the pigeon embryo. Initially, we tested the electrophoretic patterns of proteins in different egg compartments throughout development. Then, we used lysozyme as a reference protein to follow the egg white transfer, and we measured its activity using Micrococcus lysodeikticus as a substrate...
January 3, 2018: Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution
https://www.readbyqxmd.com/read/29288189/the-renal-parenchyma-evaluation-of-a-novel-ultrasound-measurement-to-assess-fetal-renal-development-protocol-for-an-observational-longitudinal-study
#13
Sonja Brennan, Michal Schneider, David Watson, Yogavijayan Kandasamy, Donna Rudd
INTRODUCTION: Disorders of fetal growth, such as intrauterine growth restriction (IUGR) and large for gestational age (LGA), have been found to have a profound effect on the development of the fetal kidney. Abnormal kidney development is associated with hypertension and chronic kidney disease later in life. This study will use a novel ultrasound measurement to assess the renal parenchymal growth and kidney arterial blood flow in the fetus to evaluate the development of the fetal kidneys and provide an indirect estimate of nephron number...
December 28, 2017: BMJ Open
https://www.readbyqxmd.com/read/29259487/evidence-of-exposure-to-chemicals-and-heavy-metals-during-pregnancy-in-japanese-women
#14
Ryo Maekawa, Rie Ito, Yusuke Iwasaki, Koichi Saito, Kazuhiko Akutsu, Satoshi Takatori, Rie Ishii, Fumio Kondo, Yoshikazu Arai, Jun Ohgane, Kunio Shiota, Tsunehisa Makino, Norihiro Sugino
Purpose: Prenatal exposure to environmental chemicals is a growing concern, because such exposures have been shown to be associated with various diseases. The levels of chemicals and heavy metals in maternal blood, cord blood, maternal urine and amniotic fluid in Japanese pregnant women were investigated. Methods: A total of 145 women, including 14 fetal growth restriction cases, were included in the present study. The levels of phthalates (di[2-ethylhexyl]phthalate and mono[2-ethylhexyl]phthalate), perfluorinated compounds (perfluorooctane sulfonate, perfluorohexanoic acid, perfluorooctanoic acid, and perfluorononanoic acid), pesticides (dimethylphosphate, dimethylthiophosphate, diethylphosphate, diethylthiophosphate, 3-phenoxybenzoic acid, and octachlorodipropyl ether), bisphenol A, nicotine (nicotine, nornicotine, cotinine, norcotinine, and trans-3'-hydroxycotinine), polybrominated diphenyl ethers, and heavy metals were measured...
October 2017: Reproductive Medicine and Biology
https://www.readbyqxmd.com/read/29240677/amniotic-fluid-arginine-from-gestational-weeks-13-to-15-is-a-predictor-of-birth-weight-length-and-head-circumference
#15
Astrid Bjørke-Jenssen, Per Magne Ueland, Anne-Lise Bjørke-Monsen
Arginine is a constituent of proteins and a precursor for polyamines and nitric oxide, and is essential for placentation, angiogenesis, and growth. Maternal plasma arginine concentrations are found to be lower in pregnancies complicated by fetal growth restriction, and arginine supplementation in later pregnancy is reported to increase birth weight. We measured arginine and the metabolites asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) in the amniotic fluid obtained in pregnancy weeks 13 to 15 from 363 pregnancies with a documented normal outcome and related the concentrations to birth weight, length, and head circumference...
December 14, 2017: Nutrients
https://www.readbyqxmd.com/read/29232399/maternal-white-blood-cell-count-cannot-identify-the-presence-of-microbial-invasion-of-the-amniotic-cavity-or-intra-amniotic-inflammation-in-women-with-preterm-prelabor-rupture-of-membranes
#16
Ivana Musilova, Lenka Pliskova, Romana Gerychova, Petr Janku, Ondrej Simetka, Petr Matlak, Bo Jacobsson, Marian Kacerovsky
OBJECTIVE: The main aim of this study was to determine the relationship between the maternal white blood cell (WBC) count at the time of hospital admission in pregnancies complicated by preterm prelabor rupture of membranes (PPROM) and the presence of microbial invasion of the amniotic cavity (MIAC) and/or intra-amniotic inflammation (IAI). The second aim was to test WBC diagnostic indices with respect to the presence of MIAC and/or IAI. METHODS: Four hundred and seventy-nine women with singleton pregnancies complicated by PPROM, between February 2012 and June 2017, were included in this study...
2017: PloS One
https://www.readbyqxmd.com/read/29219113/diagnostic-role-of-microrna-expression-profile-in-the-prenatal-amniotic-fluid-samples-of-pregnant-women-with-down-syndrome
#17
Emin Karaca, Ayça Aykut, Biray Ertürk, Burak Durmaz, Ahmet Güler, Barış Büke, Ahmet Özgür Yeniel, Ahmet Mete Ergenoğlu, Ferda Özkınay, Mehmet Özeren, Mert Kazandı, Fuat Akercan, Sermet Sağol, Cumhur Gündüz, Özgür Çoğulu
BACKGROUND: Down syndrome is the most common chromosomal anomaly in humans. Down syndrome is the most common chromosomal anomaly in humans affecting people from every race and age. Most of the cases are can be diagnosed by prenatal diagnostic methods in pregnancy. Due to the longtime of culture method applied for prenatal diagnosis, genetic analysis has been developed and developing for rapid diagnosis. For this reason, the effective use of miRNAs was investigated in the rapid analysis of prenatal samples with Down syndrome...
December 8, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/29210307/amniotic-fluid-oxidant-antioxidant-status-in-foetal-congenital-nervous-system-anomalies
#18
Numan Cim, Harun Egemen Tolunay, Erbil Karaman, Barıs Boza, Mustafa Bilici, Orkun Çetin, Recep Yıldızhan, Hanım Guler Sahin
Objective This study aimed to evaluate the oxidant-antioxidant status of amniotic fluid in pregnant women with foetal congenital malformations of the central nervous system. Methods We studied pregnant women with foetal congenital nervous system anomalies at 16-22 weeks' gestation (n = 36). The control group (n = 30) consisted of pregnant women at the same gestational age who underwent amniocentesis, resulting in a normal karyotype. We analysed glutathione, catalase, and malondialdehyde levels in amniotic fluid...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/29195161/prenatal-and-pubertal-testosterone-affect-brain-lateralization
#19
T Beking, R H Geuze, M van Faassen, I P Kema, B P C Kreukels, T G G Groothuis
After decades of research, the influence of prenatal testosterone on brain lateralization is still elusive, whereas the influence of pubertal testosterone on functional brain lateralization has not been investigated, although there is increasing evidence that testosterone affects the brain in puberty. We performed a longitudinal study, investigating the relationship between prenatal testosterone concentrations in amniotic fluid, pubertal testosterone concentrations in saliva, and brain lateralization (measured with functional Transcranial Doppler ultrasonography (fTCD)) of the Mental Rotation, Chimeric Faces and Word Generation tasks...
November 6, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29173937/relationship-between-ultrasonic-marker-of-fetal-lung-maturity-and-lamellar-body-count
#20
Khadije Rezaie Keikhaie, Kolsoum Rezaie Kahkhaie, Nooshin Mohammadi, Nooshin Amjadi, Aliye Ahmadi Forg, Abbas Ali Ramazani
BACKGROUND: The aim of this study was prediction the fetal lung maturity by ultrasonic markers and comparison by lamellar body count and fetal outcome. METHODS: A prospective Longitudinal study Department of perinatology of performed Emam Khomeini hospital and Mirza Kochak Khan Hospital in Tehran, Iran from March 2013 to January 2014. 100 pregnant women (37-40 weeks of gestation) who were admitted for elective cesarean section and referred for an obstetric ultrasound scan at the same day of their elective cesarean section were included...
January 2017: Journal of the National Medical Association
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