Jan Jakub Lica, Katarzyna Gucwa, Mateusz Heldt, Anna Stupak, Natalia Maciejewska, Natalia Ptaszyńska, Anna Łęgowska, Bhaskar Pradhan, Agata Gitlin-Domagalska, Dawid Dębowski, Joanna Jakóbkiewicz-Banecka, Krzysztof Rolka
The fusion of penetrating peptides (PPs), e.g., cell penetration peptides (CPPs) or antimicrobial peptides (AMPs), together with antimicrobial agents is an expanding research field. Specific AMPs, such as lactoferricin B (LfcinB), have demonstrated strong antibacterial, antifungal, and antiparasitic activity, as well as valuable anticancer activity, proving beneficial in the development of anticancer conjugates. The resulting conjugates offer potential dual functionality, acting as both an anticancer and an antimicrobial agent...
February 1, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry