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probiotics in preterm

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https://www.readbyqxmd.com/read/28100322/-association-between-risk-factors-during-maternal-pregnancy-and-the-neonatal-period-and-childhood-bronchial-asthma
#1
Hui-Qin Zhang, Rui Fan, Jing-Jing Zhang, Xiao-Juan Tao, Xin Sun
OBJECTIVE: To study the association of the risk factors during maternal pregnancy and the neonatal period with childhood bronchial asthma. METHODS: A total of 306 children with asthma (asthma group) and 250 healthy children (control group) were enrolled. Their clinical data during the neonatal period and the maternal data during pregnancy were retrospectively studied. RESULTS: The univariate analysis showed that there were significant differences in the rates of maternal use of antibiotics during pregnancy, use of antibiotics and probiotics during the neonatal period, preterm birth, cesarean section, low birth weight, and breast feeding (>6 months) between the asthma and control groups (P<0...
January 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28064261/clinical-effects-of-prebiotics-in-pediatric-population
#2
Rok Orel, Lea Vodušek Reberšak
CONTEXT: Prebiotics are non-digestible components of food that in a selective manner trigger the expansion of microbes in the gut with valuable effects for the health of the host. In our document, current literature pertaining to the clinical effects of the use of prebiotics for the treatment and prevention of some common pediatric pathology such as infantile colic, constipation, absorption of minerals, weight gain, diarrhea, respiratory infections, and eczema is reviewed. EVIDENCE: Data was collected through search of the MEDLINE, PubMed, UpToDate, Cochrane Database of Systemic Reviews, and the Cochrane Controlled Trials Register database as well as through references from relevant articles, all until September 2015...
December 15, 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/28056921/bifidobacterium-adolescentis-protects-against-necrotizing-enterocolitis-and-upregulates-tollip-and-sigirr-in-premature-neonatal-rats
#3
Wenshen Wu, Yanli Wang, Jingjing Zou, Fang Long, Huiheng Yan, Lijuan Zeng, Yunbin Chen
BACKGROUND: Necrotizing enterocolitis (NEC) is a serious gastrointestinal disorder that is often seen in premature infants. Probiotics decrease the risk of NEC; however, the mechanism by which probiotics work is not clear. The goal of this study was to evaluate the preventive effect of Bifidobacterium adolescentis in an NEC rat model. METHODS: Sprague-Dawley neonatal rats were obtained by caesarean section after 20-21 d gestation and randomly divided into the following 3 groups: dam fed (DF), formula fed (FF), and formula + B...
January 5, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28050019/survey-and-evidence-based-review-of-probiotics-used-in-very-low-birth-weight-preterm-infants-within-the-united-states
#4
S Viswanathan, C Lau, H Akbari, C Hoyen, M C Walsh
No abstract text is available yet for this article.
January 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/27793494/probiotics-prevent-candida-colonization-and-invasive-fungal-sepsis-in-preterm-neonates-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#5
REVIEW
Hua-Jian Hu, Guo-Qiang Zhang, Qiao Zhang, Shristi Shakya, Zhong-Yue Li
To investigate whether probiotic supplementation could reduce the risk of fungal infection in preterm neonates in neonatal intensive care units (NICUs), we systematically searched PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials databases for randomized controlled trials (RCTs) focusing on the effect of probiotics on fungal infection in preterm neonates. The outcomes of interest were Candida colonization and invasive fungal sepsis. Seven trials involving 1371 preterm neonates were included...
September 14, 2016: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/27761306/prevention-of-necrotizing-enterocolitis-with-probiotics-a-systematic-review-and-meta-analysis
#6
Sonja C Sawh, Santosh Deshpande, Sandy Jansen, Christopher J Reynaert, Philip M Jones
CONTEXT: Necrotizing enterocolitis (NEC) is the most frequent gastrointestinal emergency in neonates. The microbiome of the preterm gut may regulate the integrity of the intestinal mucosa. Probiotics may positively contribute to mucosal integrity, potentially reducing the risk of NEC in neonates. OBJECTIVE: To perform an updated systematic review and meta-analysis on the efficacy and safety of probiotics for the prevention of NEC in premature infants. DATA SOURCES: Structured searches were performed in: Medline, Embase, and the Cochrane Central Register of Controlled Trials (all via Ovid, from 2013 to January 2015)...
2016: PeerJ
https://www.readbyqxmd.com/read/27751204/-research-advances-in-breastfeeding
#7
Xi-Hong Liu
Human breast milk is the most natural and ideal food for the baby. Breastfeeding provides benefits for maternal and child health, child immune function, growth and development, and society. The operation of human milk bank and the use of donor human milk undoubtedly provides a new way of nutrition support for the preterm infants without their own mother's milk and a new kind of treatment for other diseases. Present research on the composition of breast milk focuses on the variety and quantity of proteins, bioactive substances, probiotics and cell population...
October 2016: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/27744438/vaginal-probiotic-administration-in-the-management-of-preterm-premature-rupture-of-membranes
#8
George J Daskalakis, Alexis K Karambelas
OBJECTIVE: To examine the influence of vaginal probiotic administration as an adjunct to standard antibiotic treatment on perinatal outcome in women with preterm premature rupture of membranes (PPROM). MATERIALS AND METHODS: This was a prospective randomized trial of cases with PPROM (24-34 weeks) that were admitted to our department between 2011 and 2015. Forty-nine cases received vaginal probiotics for 10 days in combination with antibiotic prophylaxis and were compared to 57 others that received only antibiotics for the same time period...
October 15, 2016: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/27727257/-lactobacillus-rhamnosus-sepsis-in-a-preterm-infant-associated-with-probiotic-integrator-use-a-case-report
#9
Manuela Molinaro, Massimo Aiazzi, Antonio La Torre, Elisabetta Cini, Roberto Banfi
Preterm infants are at high risk of neonatal sepsis. We report a case of a preterm infant under prophylaxis with Lactobacillus Rhamnosus for necrotizing enterocolitis; the child develops neonatal sepsis by Lactobacillus Rhamnosus. The infection is improved after probiotic withdrawal and had complete remission after 20 days of specific antibiotic therapy.
September 2016: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/27671183/efficacy-of-probiotics-versus-placebo-in-the-prevention-of-necrotizing-enterocolitis-in-preterm-very-low-birth-weight-infants-a-double-blind-randomized-controlled-trial
#10
Tanjina Chowdhury, Muhammad Manajjir Ali, Muhammad Monir Hossain, Jugindra Singh, Abu Noyeem Muhammad Yousuf, Fatema Yasmin, Fazle Rabbi Chowdhury
OBJECTIVE: To evaluate the efficacy of orally administered probiotics in preventing necrotizing enterocolitis (NEC) in preterm very low birth weight (VLBW) infants. STUDY DESIGN: Arandomized double blind controlled trial. PLACE AND DURATION OF STUDY: The Paediatrics Department of Sylhet M.A.G. Osmani Medical College Hospital, Sylhet Bangladesh, from July 2012 to June 2015. METHODOLOGY: Preterm (28 - 33 weeks gestation) VLBW (birth weight 1000 - 1499 g) neonates were enrolled...
September 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/27633108/probiotics-prebiotics-and-synbiotics-for-the-prevention-of-necrotizing-enterocolitis
#11
REVIEW
Kathene C Johnson-Henry, Thomas R Abrahamsson, Richard You Wu, Philip M Sherman
Necrotizing enterocolitis (NEC) is a devastating intestinal disease in preterm infants characterized by barrier disruption, intestinal microbial dysbiosis, and persistent inflammation of the colon, which results in high mortality rates. Current strategies used to manage this disease are not sufficient, although the use of human breast milk reduces the risk of NEC. Mother's milk is regarded as a fundamental nutritional source for neonates, but pasteurization of donor breast milk affects the composition of bioactive compounds...
September 2016: Advances in Nutrition
https://www.readbyqxmd.com/read/27622346/effects-of-clostridium-butyricum-and-bifidobacterium-on-btla-expression-on-cd4-t-cells-and-lymphocyte-differentiation-in-late-preterm-infants
#12
Shi-Fa Zhang, Zong-Sheng Tang, Ling Tong, Xiang-Xiang Tao, Qi-Feng Suo, Xue-Mei Xu
BACKGROUND & AIMS: Probiotics is recognized to promote growth performance and immune function via balancing the intestinal microflora. Live clostridium butyricum and bifidobacterium combined powder (LCBBCP) has been widely to treat intestinal dysbacteriosis in newborns in China. This study was undertaken to investigate the effects of the combined probiotics on the expression of B and T lymphocyte attenuator (BTLA) on CD4(+) T cells and the differentiation of lymphocyte subsets in late preterm infants...
November 2016: Microbial Pathogenesis
https://www.readbyqxmd.com/read/27594381/a-randomised-controlled-trial-of-the-probiotic-bifidobacterium-breve-bbg-001-in-preterm-babies-to-prevent-sepsis-necrotising-enterocolitis-and-death-the-probiotics-in-preterm-infants-pips-trial
#13
Kate Costeloe, Ursula Bowler, Peter Brocklehurst, Pollyanna Hardy, Paul Heal, Edmund Juszczak, Andy King, Nicola Panton, Fiona Stacey, Angela Whiley, Mark Wilks, Michael R Millar
BACKGROUND: Necrotising enterocolitis (NEC) and late-onset sepsis remain important causes of death and morbidity in preterm babies. Probiotic administration might strengthen intestinal barrier function and provide protection; this is supported by published meta-analyses, but there is a lack of large well-designed trials. OBJECTIVE: To test the use of the probiotic Bifidobacterium breve strain BBG-001 to prevent NEC, late-onset sepsis and death in preterm babies while monitoring probiotic colonisation of participants...
August 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27589549/necrotizing-enterocolitis-in-premature-infants-and-newborns
#14
M J Mϋller, T Paul, S Seeliger
Necrotizing enterocolitis (NEC) is the most common acquired disease of the gastrointestinal tract (GIT) in premature infants and newborns. It is defined as an ulcerative inflammation of the intestinal wall. The clinical signs of incipient NEC are often very discrete, and range from localized intestinal symptoms to generalized signs of sepsis. NEC is classified depending on its severity into disease states according to the modified Bell's Classification. Treatment of NEC ranges, depending on its severity, from a conservative therapeutic approach to surgery with resection of the affected parts of the intestine...
September 16, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27583387/survey-and-evidence-based-review-of-probiotics-used-in-very-low-birth-weight-preterm-infants-within-the-united-states
#15
S Viswanathan, C Lau, H Akbari, C Hoyen, M C Walsh
OBJECTIVE: Data from multiple clinical trials, mostly conducted outside the US, indicate that probiotic prophylaxis is an effective intervention for prevention of necrotizing enterocolitis (NEC) in preterm infants. Probiotics are routinely used in many countries. However, in the US, probiotic use in preterm infants is limited (6.7% of very low birth weight (VLBW) infants in the US were exposed to probiotics in 2014, Vermont Oxford Network (VON)). Probiotic products are often considered in 'generic' terms, but considerable variation exists between commercially available probiotics in terms of their quantity and quality...
December 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/27545195/necrotising-enterocolitis-and-mortality-in-preterm-infants-after-introduction-of-probiotics-a-quasi-experimental-study
#16
Noor Samuels, Rob van de Graaf, Jasper V Been, Rogier C J de Jonge, Lidwien M Hanff, René M H Wijnen, René F Kornelisse, Irwin K M Reiss, Marijn J Vermeulen
Evidence on the clinical effectiveness of probiotics in the prevention of necrotising enterocolitis (NEC) in preterm infants is conflicting and cohort studies lacked adjustment for time trend and feeding type. This study investigated the association between the introduction of routine probiotics (Lactobacillus acidophilus and Bifidobacterium bifidum; Infloran(®)) on the primary outcome 'NEC or death'. Preterm infants (gestational age <32 weeks or birth weight <1500 gram) admitted before (Jan 2008-Sep 2012; n = 1288) and after (Oct 2012-Dec 2014; n = 673) introduction of probiotics were compared...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27543379/risk-factors-for-necrotizing-enterocolitis-in-neonates-a-retrospective-case-control-study
#17
Qi Lu, Shupeng Cheng, Min Zhou, Jialin Yu
BACKGROUND: Necrotizing enterocolitis (NEC) in neonates is devastating, and risk-factor identification is crucial. This study aimed to evaluate risk factors for NEC in different gestational age (GA) groups. METHODS: Risk factors associated with NEC were investigated using a retrospective case-control design. Patients with Bell's Stage NEC≥II were divided into three groups based on GA: I, <34 weeks; II, ≥34 weeks but <37 weeks; III, ≥37 weeks. Each case was paired with two GA- and weight-matched controls...
June 22, 2016: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/27391560/barriers-to-knowledge-translation-regarding-the-use-of-probiotics-as-a-risk-reduction-strategy-for-necrotizing-enterocolitis
#18
Sharon Anderson
BACKGROUND: Increasingly, evidence supports enteral probiotics are an important risk-reduction strategy for necrotizing enterocolitis (NEC) among very low birth-weight and extremely low birth-weight preterm infants. Yet, the majority of providers remain reluctant to implement practice changes. PURPOSE: The aim of this study was to better understand the discrepancy between the available evidence and clinical practice regarding the use of probiotics and other NEC prevention strategies in New Jersey...
August 2016: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/27343151/necrotizing-enterocolitis-and-preterm-infant-gut-bacteria
#19
REVIEW
Barbara B Warner, Phillip I Tarr
Necrotizing enterocolitis remains an intractable consequence of preterm birth. Gut microbial communities, especially bacterial communities, have long been suspected to play a role in the development of necrotizing enterocolitis. Direct-from-stool nucleic acid sequencing technology now offers insights into the make-up of these communities. Data are now converging on the roles of Gram-negative bacteria as causative agents, despite the dynamic nature of bacterial populations, the varying technologies and sampling strategies, and the overall small sample sizes in these case-control studies...
December 2016: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27342046/effect-of-probiotics-on-vaginal-health-in-pregnancy-effpro-%C3%A2-a-randomized-controlled-trial
#20
Christian Gille, Bettina Böer, Matthias Marschal, Michael S Urschitz, Volker Heinecke, Verena Hund, Sarah Speidel, Inge Tarnow, Ioannis Mylonas, Axel Franz, Corinna Engel, Christian F Poets
BACKGROUND: Preterm delivery is a leading cause of neonatal morbidity and death. It often results from chorioamnionitis, which is a complication of bacterial vaginosis. Probiotics are effective in the treatment of bacterial vaginosis in women who were not pregnant; studies in pregnant woman are missing. OBJECTIVE: The purpose of this study was to evaluate whether an oral probiotic food supplement supports the maintenance or restoration of a normal vaginal microbiota during pregnancy...
November 2016: American Journal of Obstetrics and Gynecology
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