keyword
https://read.qxmd.com/read/33599473/decimeter-scale-atomically-thin-graphene-membranes-for-gas-liquid-separation
#21
JOURNAL ARTICLE
Dandan Hou, Shengping Zhang, Xiaobo Chen, Ruiyang Song, Dongxu Zhang, Ayan Yao, Jiayue Sun, Wenxuan Wang, Luzhao Sun, Buhang Chen, Zhongfan Liu, Luda Wang
Graphene holds great potential for fabricating ultrathin selective membranes possessing high permeability without compromising selectivity and has attracted intensive interest in developing high-performance separation membranes for desalination, natural gas purification, hemodialysis, distillation, and other gas-liquid separation. However, the scalable and cost-effective synthesis of nanoporous graphene membranes, especially designing a method to produce an appropriate porous polymer substrate, remains very challenging...
March 3, 2021: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/32828446/enhanced-prediction-of-hemoglobin-concentration-in-a-very-large-cohort-of-hemodialysis-patients-by-means-of-deep-recurrent-neural-networks
#22
JOURNAL ARTICLE
Oscar J Pellicer-Valero, Isabella Cattinelli, Luca Neri, Flavio Mari, José D Martín-Guerrero, Carlo Barbieri
Erythropoiesis Stimulating Agents (ESAs) have become a standard anemia management tool for End Stage Renal Disease (ESRD) patients. However, dose optimization constitutes an extremely challenging task due to huge inter and intra-patient variability in the responses to ESA administration. Current data-based approaches to anemia control focus on learning accurate hemoglobin prediction models, which can be later utilized for testing competing treatment choices and choosing the optimal one. These methods, despite being proven effective in practice, present several shortcomings which this paper intends to tackle...
July 2020: Artificial Intelligence in Medicine
https://read.qxmd.com/read/32438852/arteriovenous-access-in-hemodialysis-a-multidisciplinary-perspective-for-future-solutions
#23
REVIEW
Bernd Stegmayr, Christian Willems, Thomas Groth, Albino Martins, Nuno M Neves, Khosrow Mottaghy, Andrea Remuzzi, Beat Walpoth
In hemodialysis, vascular access is a key issue. The preferred access is an arteriovenous fistula on the non-dominant lower arm. If the natural vessels are insufficient for such access, the insertion of a synthetic vascular graft between artery and vein is an option to construct an arteriovenous shunt for punctures. In emergency situations and especially in elderly with narrow and atherosclerotic vessels, a cuffed double-lumen catheter is placed in a larger vein for chronic use. The latter option constitutes a greater risk for infections while arteriovenous fistula and arteriovenous shunt can fail due to stenosis, thrombosis, or infections...
January 2021: International Journal of Artificial Organs
https://read.qxmd.com/read/31365145/increased-risk-of-bone-fractures-in-hemodialysis-patients-treated-with-proton-pump-inhibitors-in-real-world-results-from-the-dialysis-outcomes-and-practice-patterns-study-dopps
#24
JOURNAL ARTICLE
Maria Fusaro, Graziella D'Arrigo, Annalisa Pitino, Giorgio Iervasi, Francesca Tentori, Bruce Robinson, Andrea Aghi, Brian Bieber, Keith Mccullogh, Fabrizio Fabris, Mario Plebani, Sandro Giannini, Maurizio Gallieni, Giovanni Tripepi
Long-term treatment with proton pump inhibitors (PPIs) is associated with an increased risk of fractures in the general population. PPIs are widely prescribed to dialysis patients but to date no study has specifically tested, by state-of-art statistical methods, the relationship between use of PPIs and fractures in this patient population. This study aimed to assess whether use of PPIs is associated with bone fractures (ie, hip fractures and fractures other than hip fractures) in a large international cohort of hemodialysis patients...
December 2019: Journal of Bone and Mineral Research
https://read.qxmd.com/read/30547238/prediction-of-hemodialysis-timing-based-on-lvw-feature-selection-and-ensemble-learning
#25
JOURNAL ARTICLE
Chang-Zhu Xiong, Minglian Su, Zitao Jiang, Wei Jiang
We propose an improved model based on LVW embedded model feature extractor and ensemble learning for improving prediction accuracy of hemodialysis timing in this paper. Due to this drawback caused by feature extraction models, we adopt an enhanced LVW embedded model to search the feature subset by stochastic strategy, which can find the best feature combination that are most beneficial to learner performance. In the model application, we present an improved integrated learners for model fusion to reduce errors caused by overfitting problem of the single classifier...
December 13, 2018: Journal of Medical Systems
https://read.qxmd.com/read/30124874/pd-1-inhibitor-immune-related-adverse-events-in-patients-with-preexisting-endocrine-autoimmunity
#26
JOURNAL ARTICLE
Halis Kaan Akturk, Aimon Alkanani, Zhiyuan Zhao, Liping Yu, Aaron W Michels
Context: Immune checkpoint inhibitors, including monoclonal antibodies directed against programmed cell death protein 1 (PD-1) and its ligand, have emerged as beneficial cancer immunotherapies. These therapies are known to cause immune-related side effects; however, their role in patients with a preexisting autoimmune disease is not clear. Case Description: We describe two cases of anti-PD-1 immune-related adverse events. A 52-year-old male with longstanding type 1 diabetes (T1D), long-term stable kidney transplant, and hypothyroidism received two separate anti-PD-1 monoclonal antibodies for metastatic melanoma...
October 1, 2018: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/28010886/reappraisal-in-two-european-cohorts-of-the-prognostic-power-of-left-ventricular-mass-index-in-chronic-kidney-failure
#27
MULTICENTER STUDY
Giovanni Tripepi, Bruno Pannier, Graziella D'Arrigo, Francesca Mallamaci, Carmine Zoccali, Gerard London
Left ventricular hypertrophy is a strong causal risk factor of cardiovascular morbidity and death in end stage kidney failure, and its prognostic value is taken for granted in this population. However, the issue has never been formally tested by state-of-art prognostic analyses. Therefore, we determined the prognostic power of the left ventricular mass index (LVMI) for all-cause and cardiovascular death beyond and above that provided by well validated clinical risk scores, the annualized rate of occurrence cohort risk scores (ARO, all cause death risk and cardiovascular risk)...
March 2017: Kidney International
https://read.qxmd.com/read/27717781/1-3-%C3%A3-d-glucan-testing-is-highly-specific-in-patients-undergoing-dialysis-treatment
#28
JOURNAL ARTICLE
Juergen Prattes, Daniel Schneditz, Florian Prüller, Eva Jaindl, Notburga Sauseng, Martin Hoenigl, Gernot Schilcher, Robert Krause
BACKGROUND: The aim of this combined in-vitro and in-vivo study was to investigate whether state of the art dialysis modalities produce false positive serum 1,3-ß-d-Glucan (BDG) levels. METHODS: Dialysis fluid for simulated dialysis treatments was spiked with BDG from different sources. Samples were taken from the dialysate and dialyzer blood compartments at various time points. In addition, serum samples were obtained in three groups of patients without invasive fungal disease: a...
January 2017: Journal of Infection
https://read.qxmd.com/read/25319545/dealing-with-stuck-hemodialysis-catheter-state-of-the-art-and-tips-for-the-nephrologist
#29
REVIEW
Giacomo Forneris, Daniele Savio, Pietro Quaretti, Ilaria Fiorina, Pasqualina Cecere, Marco Pozzato, Marco Trogolo, Dario Roccatello
The term stuck catheter refers to the condition in which a catheter is not removable from a central vein using standard techniques. Although it is a rare complication, in the last few years it has been reported ever more frequently in hemodialysis due to the widespread use of tunneled catheters. Poor knowledge of the correct procedures and limited experience and training of the specialist in facing this problem are the main reasons for catheter internalization. Stuck catheter is often diagnosed by the nephrologist, who should be competent enough to manage this clinical complication...
December 2014: Journal of Nephrology
https://read.qxmd.com/read/25181734/hierarchical-lung-field-segmentation-with-joint-shape-and-appearance-sparse-learning
#30
JOURNAL ARTICLE
Yeqin Shao, Yaozong Gao, Yanrong Guo, Yonghong Shi, Xin Yang, Dinggang Shen
Lung field segmentation in the posterior-anterior (PA) chest radiograph is important for pulmonary disease diagnosis and hemodialysis treatment. Due to high shape variation and boundary ambiguity, accurate lung field segmentation from chest radiograph is still a challenging task. To tackle these challenges, we propose a joint shape and appearance sparse learning method for robust and accurate lung field segmentation. The main contributions of this paper are: 1) a robust shape initialization method is designed to achieve an initial shape that is close to the lung boundary under segmentation; 2) a set of local sparse shape composition models are built based on local lung shape segments to overcome the high shape variations; 3) a set of local appearance models are similarly adopted by using sparse representation to capture the appearance characteristics in local lung boundary segments, thus effectively dealing with the lung boundary ambiguity; 4) a hierarchical deformable segmentation framework is proposed to integrate the scale-dependent shape and appearance information together for robust and accurate segmentation...
September 2014: IEEE Transactions on Medical Imaging
https://read.qxmd.com/read/24666929/effects-of-music-on-complications-during-hemodialysis-for-chronic-renal-failure-patients
#31
RANDOMIZED CONTROLLED TRIAL
Adalet Koca Kutlu, Ayşe Gül Eren
The study was planned as a case-control study to examine the effects of music on some of the complications experienced by chronic renal failure (CRF) patients during hemodialysis. A total of 60 patients (30 intervention and 30 control) diagnosed with end-stage renal failure undergoing hemodialysis treatment participated in this study. The study was conducted in Manisa Merkez Efendi State Hospital Hemodialysis Unit and Manisa Özel Anemon Hemodialysis between April 2012 and July 2012. The intervention group listened 30 minutes in each session (12 total sessions) Turkish art music at the beginning of the third hour of their hemodialysis sessions...
October 2014: Hemodialysis International
https://read.qxmd.com/read/23868100/modeling-of-oxidized-pth-oxpth-and-non-oxidized-pth-n-oxpth-receptor-binding-and-relationship-of-oxidized-to-non-oxidized-pth-in-children-with-chronic-renal-failure-adult-patients-on-hemodialysis-and-kidney-transplant-recipients
#32
JOURNAL ARTICLE
Berthold Hocher, Dominik Oberthür, Torsten Slowinski, Uwe Querfeld, Franz Schaefer, Anke Doyon, Martin Tepel, Heinz J Roth, Hans J Grön, Christoph Reichetzeder, Christian Betzel, Franz P Armbruster
BACKGROUND: The biological properties of oxidized and non-oxidized PTH are substantially different. Oxidized PTH (oxPTH) loses its PTH receptor-stimulating properties, whereas non-oxidized PTH (n-oxPTH) is a full agonist of the receptor. This was described in more than 20 well published studies in the 1970(s) and 80(s). However, PTH oxidation has been ignored during the development of PTH assays for clinical use so far. Even the nowadays used third generation assay systems do not consider oxidation of PTH We recently developed an assay to differentiate between oxPTH and n-oxPTH...
2013: Kidney & Blood Pressure Research
https://read.qxmd.com/read/23780703/hepatitis-c-virus-infection-in-the-maghreb-region
#33
REVIEW
Sayeh Ezzikouri, Pascal Pineau, Soumaya Benjelloun
Hepatitis C is a global health problem with a worldwide prevalence of about 3% (around 170 million people). Hepatitis C virus (HCV) is major concern in the Maghreb countries, Algeria, Libya, Mauritania, Morocco, and Tunisia, but no detailed description of its epidemiology in the region is available. In the present review, a systematic search was undertaken covering HCV data available in peer-reviewed databases as well as institutional reports and regional conference meeting abstracts from the Maghreb countries...
September 2013: Journal of Medical Virology
https://read.qxmd.com/read/23451044/effect-of-isovolemic-isothermic-hemodialysis-on-cerebral-perfusion-and-vascular-stiffness-using-contrast-computed-tomography-and-pulse-wave-velocity
#34
JOURNAL ARTICLE
Ansgar Reising, Saskia Sambale, Frank Donnerstag, Julius J Schmidt, Carsten Hafer, Bernhard M W Schmidt, Jan T Kielstein
BACKGROUND: Patients undergoing hemodialysis treatment have a six-fold increased risk for stroke relative to the general population. However, the effect of hemodialysis on cerebral blood flow is poorly studied and confounding factors like blood pressure and ultrafiltration as well as temperature changes have rarely been accounted for. The aim of our study was to use state-of-the-art technology to evaluate the effect of a single dialysis session on cerebral perfusion as well as on vascular stiffness...
2013: PloS One
https://read.qxmd.com/read/22909001/biological-grafts-for-hemodialysis-access-historical-lessons-state-of-the-art-and-future-directions
#35
REVIEW
Ramanath Dukkipati, Marissa Peck, Rajiv Dhamija, Dirk M Hentschel, Tyler Reynolds, Gautam Tammewar, Todd McAllister
The vast majority of arteriovenous grafts (AVG) have been constructed using expanded polytetrafluoroethylene (ePTFE). While ePTFE grafts have the advantage of being relatively inexpensive and easy to manufacture, distribute, ship, and store, their primary patency rates are disappointing when compared with the native AVF. Though use of arteriovenous fistulas (AVF) in the United States has increased substantially, approximately 25% of hemodialysis patients continue to use AVG as their vascular access. We present here a comprehensive review of biological grafts and their use in hemodialysis vascular access...
March 2013: Seminars in Dialysis
https://read.qxmd.com/read/22894168/cognitive-function-at-2443-%C3%AE-mol-l-creatinine
#36
JOURNAL ARTICLE
Sabrina Schneider, Anne-Kathrin Malecki, Olaf Boenisch, Robby Schönfeld, Jan T Kielstein
BACKGROUND: One hallmark of uremia is the impairment of neuro-cognitive function. Anecdotal clinical description from the early days of chronic dialysis therapy impressively illustrates the improvement of those functions by chronic hemodialysis treatment. Fortunately, today, uremia is only rarely observed in industrialized countries as many patients seek medical/nephrological attention prior to the occurrence of deadly complications of uremia. CASE PRESENTATION: We report a rare case of severe uremia and describe the day to day improvement in neuro-cognitive function by dialysis using state of the arte test battery--starting at a serum creatinine of 2443 μmol/l...
2012: BMC Nephrology
https://read.qxmd.com/read/22241633/neurological-complications-of-hemodialysis-state-of-the-art
#37
REVIEW
Maria Antonietta Rizzo, Fabio Frediani, Antonio Granata, Barbara Ravasi, Daniele Cusi, Maurizio Gallieni
Neurological complications frequently affect chronic kidney disease patients. They are important causes of morbidity and mortality. We present a review of neurological complications affecting hemodialysis patients, focusing on classical and new aspects. Neurological complications can be classified as central or peripheral, but they also include other conditions such as muscle and autonomic disorders. Neurological complications in hemodialysis patients are often underdiagnosed and undertreated. Dialysis treatment can modify the clinical pattern and the course of neurological complications, but it may also directly induce some specific, dialysis-related complications...
2012: Journal of Nephrology
https://read.qxmd.com/read/22188683/historical-milestones-of-a-long-pathway
#38
REVIEW
Thomas Roy
Hemodiafiltration (HDF), developed from the combination of hemodialysis and hemofiltration, is considered to be the most effective current procedure to remove uremic toxins from the blood of kidney patients. Historically, the clinical use of HDF was for many years limited due to the cost burden related to the large amount of sterile volume replacement fluid needed. The solution offered was on-line preparation of replacement fluid from standard dialysate by means of membrane filtration. Industry opened to this concept quite early and worked on various technical solutions between the early 1980s and the late 1990s before real state-of-the-art systems became commercially available on a broad basis...
2011: Contributions to Nephrology
https://read.qxmd.com/read/21999745/anemia-management-in-patients-receiving-chronic-hemodialysis
#39
JOURNAL ARTICLE
Mayuri Thakuria, Norma J Ofsthun, Claudy Mullon, Jose A Diaz-Buxo
Anemia treatment in hemodialysis-dependent (HDD) CKD patients involves adequate supply of iron and an erythropoiesis-stimulating agent (ESA). Despite widespread usage of these agents, there is no generally accepted "standard dosing algorithm" for treating anemia in HDD-CKD patients. The new anemia Quality Incentive Program (QIP) introduced by the Centers for Medicare & Medicaid Services represents a motivation to standardize and harmonize iron and ESA regimens with interactive electronic algorithms and novel modes of deliveries for IV iron and ESA doses...
2011: Seminars in Dialysis
https://read.qxmd.com/read/21292266/electronegative-low-density-lipoprotein-origin-and-impact-on-health-and-disease
#40
REVIEW
Ana Paula Queiroz Mello, Isis Tande da Silva, Dulcineia Saes Parra Abdalla, Nágila Raquel Teixeira Damasceno
Oxidative modifications in lipoproteins (LP), especially in low-density lipoproteins (LDL), are associated with initiation and progression of atherosclerosis. The levels of a sub-fraction of LDL with oxidative characteristics, named electronegative LDL [LDL(-)], minimally oxidized LDL, and minus LDL, are known to be increased in subjects with familial hypercholesterolemia, hypertriglyceridemia, nonalcoholic steatohepatitis, diabetes mellitus, coronary artery disease, patients undergoing hemodialysis, and athletes after aerobic exercise...
April 2011: Atherosclerosis
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