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Subarachnoid haemorrhage

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https://www.readbyqxmd.com/read/29118886/polymorphic-ventricular-tachycardia-secondary-to-subarachnoid-haemorrhage-a-rare-occurrence-in-the-setting-of-normal-qtc
#1
Siddharth Paresh Shah, Priyanka Pitroda, Kinner Patel, Rahul Chandak, Timothy Ford
Subarachnoid hemorrhage (SAH) is a neurologic emergency associated with high mortality rate. Polymorphic ventricular tachycardia (VT) is a rare arrhythmia. It can occur in any setting of a long QT interval and bradycardia. This may result from a cardiomyopathy (both ischemic and non-ischemic), acute coronary ischemia, congenital long QT syndrome, electrolyte disturbances and cerebrovascular diseases. We report a rare case of polymorphic VT of unclear etiology with a normal corrected QT, likely secondary to SAH...
October 2017: Cardiology Research
https://www.readbyqxmd.com/read/29104730/haptoglobin-genotype-and-outcome-after-subarachnoid-haemorrhage-new-insights-from-a-meta-analysis
#2
Ben Gaastra, James Glazier, Diederik Bulters, Ian Galea
Haptoglobin (Hp) is a plasma protein involved in clearing extracellular haemoglobin and regulating inflammation; it exists as two genetic variants (Hp1 and Hp2). In a meta-analysis of six published studies, we confirm that Hp genotype affects short-term outcome (cerebral vasospasm and/or delayed cerebral ischemia) after subarachnoid haemorrhage (SAH) but not long-term outcome (Glasgow Outcome Score and modified Rankin Scale between one and three months). A closer examination of the heterozygous group revealed that the short-term outcome of Hp2-1 individuals clustered with that of Hp1-1 and not Hp2-2, suggesting that the presence of one Hp1 allele was sufficient to confer protection...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29102603/erythropoietin-ameliorates-early-brain-injury-after-subarachnoid-haemorrhage-by-modulating-microglia-polarization-via-the-epor-jak2-stat3-pathway
#3
Shanwu Wei, Chunxia Luo, Shanping Yu, Jin Gao, Chang Liu, Zheng Wei, Zhiren Zhang, Ling Wei, Bin Yi
Inflammatory modulation mediated by microglial M1/M2 polarization is one of the main pathophysiological processes involved in early brain injury (EBI) after subarachnoid haemorrhage (SAH). Previous studies have shown that recombinant human erythropoietin (rhEPO) alleviates EBI following experimental SAH. However, the mechanisms of this beneficial effect are still poorly understood. Recent research has suggested that EPO shows anti-inflammatory properties. Therefore, we tried to analyse whether rhEPO administration influenced microglial M1/M2 polarization in early brain injury after SAH and to identify the underlying molecular mechanism of any such effect...
November 1, 2017: Experimental Cell Research
https://www.readbyqxmd.com/read/29091255/spontaneous-intracystic-haemorrhage-of-an-arachnoid-cyst-associated-with-a-subacute-subdural-hematoma-a-case-report-and-literature-review
#4
Evren Aydogmus, Tufan Hicdonmez
Arachnoid cysts (ACs) are congenital malformations that may develop anywhere in the subarachnoid space along the cerebrospinal axis but are mostly observed in the temporal fossa and Sylvian fissure, predominantly in the left side. ACs account for 1% of all intracranial space-occupying lesions. ACs are a potential risk factor for subdural haematoma in all age groups following a traumatic head injury. Although an intracystic haemorrhage of AC without evidence of a head trauma is very rare, it may particularly develop in children and young adults who spend much more time engaged in games and forced physical exercise...
September 20, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29054916/acute-convexity-subarachnoid-haemorrhage-and-cortical-superficial-siderosis-in-probable-cerebral-amyloid-angiopathy-without-lobar-haemorrhage
#5
Andreas Charidimou, Grégoire Boulouis, Panagiotis Fotiadis, Li Xiong, Alison M Ayres, Kristin M Schwab, Mahmut Edip Gurol, Jonathan Rosand, Steve M Greenberg, Anand Viswanathan
INTRODUCTION: Acute non-traumatic convexity subarachnoid haemorrhage (cSAH) is increasingly recognised in cerebral amyloid angiopathy (CAA). We investigated: (a) the overlap between acute cSAH and cortical superficial siderosis-a new CAA haemorrhagic imaging signature and (b) whether acute cSAH presents with particular clinical symptoms in patients with probable CAA without lobar intracerebral haemorrhage. METHODS: MRI scans of 130 consecutive patients meeting modified Boston criteria for probable CAA were analysed for cortical superficial siderosis (focal, ≤3 sulci; disseminated, ≥4 sulci), and key small vessel disease markers...
October 20, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29025918/contemporary-endovascular-and-open-aneurysm-treatment-in-the-era-of-flow-diversion
#6
REVIEW
Marcus D Mazur, Philipp Taussky, Min S Park, William T Couldwell
Clinical outcomes have improved considerably over the last decade for patients with ruptured and unruptured aneurysms. Modern endovascular techniques, such as flow diversion, are associated with high aneurysm occlusion rates and have become a popular treatment modality for many types of aneurysms. However, the safety and effectiveness of flow diversion has not yet been established in trials comparing it with traditional aneurysm treatments. Moreover, there are some types of aneurysms that may not be appropriate for endovascular coiling, such as wide-necked aneurysms located at branch points of major vessels, large saccular aneurysms with multiple efferent arteries, dolichoectatic aneurysms, large aneurysms with mass effect, when there are technical complications with endovascular treatment, when patients cannot tolerate or have contraindications to antiplatelet therapy or in the setting of a subarachnoid haemorrhage...
October 12, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28992725/correction-to-olubajo-f-et-al-cranial-subarachnoid-and-subdural-haemorrhage-caused-by-spinal-melanoma-metastasis
#7
(no author information available yet)
No abstract text is available yet for this article.
August 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/28973585/characteristics-of-unruptured-compared-to-ruptured-intracranial-aneurysms-a-multicenter-case-control-study
#8
Isabel C Hostettler, Varinder S Alg, Nichole Shahi, Fatima Jichi, Stephen Bonner, Daniel Walsh, Diederik Bulters, Neil Kitchen, Martin M Brown, Henry Houlden, Joan Grieve, David J Werring
BACKGROUND: Only a minority of intracranial aneurysms rupture to cause subarachnoid hemorrhage. OBJECTIVE: To test the hypothesis that unruptured aneurysms have different characteristics and risk factor profiles compared to ruptured aneurysms. METHODS: We recruited patients with unruptured aneurysms or aneurysmal subarachnoid hemorrhages at 22 UK hospitals between 2011 and 2014. Demographic, clinical, and imaging data were collected using standardized case report forms...
July 25, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28969392/spreading-depolarization-and-acute-ischaemia-in-subarachnoid-haemorrhage-the-role-of-mass-depolarization-waves
#9
Shivani Ghoshal, Jan Claassen
No abstract text is available yet for this article.
October 1, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28959481/brain-iron-overload-following-intracranial-haemorrhage
#10
REVIEW
Thomas Garton, Richard F Keep, Ya Hua, Guohua Xi
Intracranial haemorrhages, including intracerebral haemorrhage (ICH), intraventricular haemorrhage (IVH) and subarachnoid haemorrhage (SAH), are leading causes of morbidity and mortality worldwide. In addition, haemorrhage contributes to tissue damage in traumatic brain injury (TBI). To date, efforts to treat the long-term consequences of cerebral haemorrhage have been unsatisfactory. Incident rates and mortality have not showed significant improvement in recent years. In terms of secondary damage following haemorrhage, it is becoming increasingly apparent that blood components are of integral importance, with haemoglobin-derived iron playing a major role...
December 2016: Stroke and Vascular Neurology
https://www.readbyqxmd.com/read/28956643/recovery-of-an-injured-prefronto-caudate-tract-in-a-patient-with-traumatic-brain-injury-a-diffusion-tensor-tractography-study
#11
Sung Ho Jang, Seong Ho Kim, Han Do Lee
OBJECTIVES: We report on a patient with improvement of akinetic mutism (AM), who showed recovery of an injured prefronto-caudate tract following traumatic brain injury (TBI), which was demonstrated by follow-up diffusion tensor tractographies (DTTs). CASE PRESENTATION: A 72-year-old female had suffered from head trauma resulting from falling down the stairs. She was diagnosed as subdural hematoma on the right frontal lobe and subarachnoid haemorrhage. At 5 weeks after head trauma, when starting rehabilitation, she showed no spontaneous movement or speech...
2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28951182/surgical-treatment-of-mirror-mca-aneurysms-bilateral-and-unilateral-approach
#12
Vedat Acik, Gökhan Cavus, Emre Bilgin, Ali Arslan, Yurdal Gezercan, Ali İhsan Okten
OBJECTIVE: Currently, the optimal surgical approach for bilateral aneurysms remains controversial. Alternative interventional methods, such as unilateral or bilateral approaches, have been employed during a single session or two different sessions. The unilateral approach can be employed successfully to treat contralateral aneurysms that develop in a paramedian location. However, such an approach is more difficult for treating contralateral aneurysms in more distant locations. Unilateral approach can decrease complication rates, operation time and the length of hospital stay...
September 22, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28894433/amino-acids-in-cerebrospinal-fluid-of-patients-with-aneurysmal-subarachnoid-haemorrhage-an-observational-study
#13
Bartosz Sokół, Bartosz Urbaniak, Norbert Wąsik, Szymon Plewa, Agnieszka Klupczyńska, Roman Jankowski, Barbara Więckowska, Robert Juszkat, Zenon Kokot
BACKGROUND: The authors are aware of only one article investigating amino acid concentrations in cerebrospinal fluid (CSF) in patients with ruptured intracranial aneurysms, and this was published 31 years ago. Since then, both management of subarachnoid haemorrhage (SAH) and amino acid assay techniques have seen radical alterations, yet the pathophysiology of SAH remains unclear. OBJECTIVE: To analyse the pattern of concentrations of amino acids and related compounds in patients with different outcomes following aneurysmal SAH...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28882465/remote-cerebellar-hemorrhage-caused-by-undetected-dural-tear-after-lumbar-spinal-surgery
#14
Estela Val-Jordán, Pilar Seral-Moral, Beatriz Novo-González
Remote cerebellar haemorrhage is a rare but serious complication after spinal surgery. Although the mechanism is not well known, it always occurs after loss of cerebrospinal fluid due to dural tear, not always identified, which produces remote venous bleeding. Prognosis depends largely on the severity of this bleeding. We report a case of 67-year-old female who suffered a cerebellar and subarachnoid haemorrhage and subdural haematoma after elective lumbar fusion surgery and eventually required decompressive craniectomy...
September 4, 2017: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/28876566/a-survey-of-selected-key-areas-of-management-of-south-african-neurosurgical-patients
#15
C H Daniel, M D du Trevou
BACKGROUND: Previous surveys of neurosurgical patient management, including a South African (SA) survey conducted in 2001, confirmed the existence of significant dissimilarities in management on national and international levels. This survey aimed to determine current SA neurosurgical patient management and to compare this with international trends. METHOD: Questionnaires in multiple choice question (MCQ) and free text entry format covering key areas of neurosurgical practice were emailed to SA neurosurgeons following ethics approval...
September 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28869279/life-situation-5%C3%A2-years-after-subarachnoid-haemorrhage
#16
H C Persson, L Carlsson, K S Sunnerhagen
OBJECTIVES: Subarachnoid haemorrhage (SAH) has high mortality and morbidity among survivors. SAH mainly affects young people and may result in long-term disabilities such as decreased Health-related Quality of Life (HRQoL), mental health and cognitive function. The aim of this study was to investigate the life situation 5 years after a SAH including physical/emotional status, participation and HRQoL. MATERIALS & METHODS: In this cross-sectional descriptive study, a mail survey was sent to all persons treated at a neurosurgery unit in Gothenburg, Sweden, for non-traumatic SAH in 2009-2010, approximately 5 years post-SAH...
September 4, 2017: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/28862314/working-capacity-after-a-subarachnoid-haemorrhage-a-six-year-follow-up
#17
Emma Westerlind, Hanna C Persson, Katharina S Sunnerhagen
OBJECTIVE: Subarachnoid haemorrhage can lead to long-term disabilities. It is a major health issue for the patient and can affect work capacity. The aim of this study was to investigate working capacity after subarachnoid haemorrhage from a long-term perspective, using data from national sick leave records. In addition, factors associated with working capacity were analysed. DESIGN: A retrospective cohort study. SUBJECTS/PATIENTS: A consecutive total sample of 38 working-age participants with first-ever subarachnoid haemorrhage was included...
September 1, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28854198/consequences-and-coping-strategies-six-years-after-a-subarachnoid-hemorrhage-a-qualitative-study
#18
Hanna C Persson, Karin Törnbom, Katharina S Sunnerhagen, Marie Törnbom
BACKGROUND: After a subarachnoid haemorrhage (SAH), continuing impairment is common and may impact the person's life. There is a lack of knowledge regarding long-term consequences experienced. PURPOSE: To explore experiences of the care and rehabilitation as well as the consequences and strategies used to cope with everyday life six years post SAH. METHODS: An explorative interview study with a qualitative design. Individual interviews, with open ended questions, using an interview guide were performed with sixteen participants (mean age 63, 8 men, 8 women) six years post SAH...
2017: PloS One
https://www.readbyqxmd.com/read/28841841/isolated-non-traumatic-non-aneurysmal-convexal-subarachnoid-hemorrhage-in-a-patient-with-evans-syndrome
#19
Anna Misyail Abdul Rashid, Mohamad Syafeeq Faeez Md Noh
BACKGROUND: Non-traumatic, spontaneous subarachnoid hemorrhage occurs in approximately 85% of cases where there is a ruptured saccular aneurysm. An additional 10% of cases arise from non-aneurysmal peri-mesencephalic hemorrhages. CASE PRESENTATION: We report a rare case of a young female, with underlying Evans syndrome, who was initially thought to have non-hemorrhagic stroke, eventually diagnosed having isolated non-traumatic, non-aneurysmal convexal subarachnoid haemorrhage...
August 25, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28822018/the-prevalence-of-growth-hormone-deficiency-in-survivors-of-subarachnoid-haemorrhage-results-from-a-large-single-centre-study
#20
Sumithra Giritharan, Joanna Cox, Calvin J Heal, David Hughes, Kanna Gnanalingham, Tara Kearney
OBJECTIVE: The variation in reported prevalence of growth hormone deficiency (GHD) post subarachnoid haemorrhage (SAH) is mainly due to methodological heterogeneity. We report on the prevalence of GHD in a large cohort of patients following SAH, when dynamic and confirmatory pituitary hormone testing methods are systematically employed. DESIGN: In this cross-sectional study, pituitary function was assessed in 100 patients following SAH. Baseline pituitary hormonal profile measurement and glucagon stimulation testing (GST) was carried out in all patients...
December 2017: Pituitary
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