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Subarachnoid haemorrhage

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https://www.readbyqxmd.com/read/28102428/plasma-adamts13-activity-and-von-willebrand-factor-antigen-and-activity-in-patients-with-subarachnoid-haemorrhage
#1
Monisha Kumar, Wenjing Cao, Jenny K McDaniel, Huy P Pham, Dheeraj Raju, Kelsey Nawalinski, Suzanne Frangos, David Kung, Eric Zager, Scott E Kasner, Joshua M Levine, X Long Zheng
Increased von Willebrand factor (VWF) and reduced ADAMTS13 activity are associated with arterial thrombosis. This may also be the culprit mechanism implicated in delayed cerebral ischaemia after aneurysmal subarachnoid haemorrhage (SAH). It was our objective to determine plasma VWF and ADAMTS13 in patients with SAH and healthy subjects; and to explore the levels of those markers and outcome after SAH. Forty consecutive patients were enrolled between September 2007 and April 2014 in a pilot study. Plasma samples were collected from SAH patients on post-bleed day (PBD) 0, 1, 3, 5, 7 and 10 and healthy controls...
January 19, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/28100721/meta-analysis-of-timing-of-endovascular-aneurysm-treatment-in-subarachnoid-haemorrhage-inconsistent-results-of-early-treatment-within-1-day
#2
Sapna Rawal, Paula Alcaide-Leon, R Loch Macdonald, Gabriel J E Rinkel, J Charles Victor, Timo Krings, Moira K Kapral, Andreas Laupacis
BACKGROUND AND PURPOSE: To systematically review and meta-analyse the data on impact of timing of endovascular treatment in aneurysmal subarachnoid haemorrhage (SAH) to determine if earlier treatment is associated with improved clinical outcomes and reduced case fatality. METHODS: We searched MEDLINE, Cochrane database, EMBASE and Web of Science to identify studies for inclusion. The measures of effect utilised were unadjusted/adjusted ORs. Effect estimates were combined using random effects models for each outcome (poor outcome, case fatality); heterogeneity was assessed using the I(2) index...
January 18, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28074401/adipsic-diabetes-insipidus-in-adult-patients
#3
REVIEW
Martín Cuesta, Mark J Hannon, Christopher J Thompson
INTRODUCTION: Adipsic diabetes insipidus (ADI) is a very rare disorder, characterized by hypotonic polyuria due to arginine vasopressin (AVP) deficiency and failure to generate the sensation of thirst in response to hypernatraemia. As the sensation of thirst is the key homeostatic mechanism that prevents hypernatraemic dehydration in patients with untreated diabetes insipidus (DI), adipsia leads to failure to respond to aquaresis with appropriate fluid intake. This predisposes to the development of significant hypernatraemia, which is the typical biochemical manifestation of adipsic DI...
January 10, 2017: Pituitary
https://www.readbyqxmd.com/read/28065963/complications-of-in-patient-cerebral-angiography-comparison-between-patients-with-and-without-sub-arachnoid-haemorrhage
#4
Yaseen Rauf, Usman Tariq Siddiqui, Gohar Javed
OBJECTIVE: To compare complications of cerebral angiography among patients with and without subarachnoid haemorrhage. METHODS: This retrospective study was conducted at the Aga Khan University Hospital, Karachi, and comprised records of patients undergoing inpatient therapeutic and diagnostic cerebral angiographies from 2001 to 2010. The patients were divided into subarachnoid and non-subarachnoid haemorrhage groups. During the study period no modifications were made to the operational protocol and all patients were subjected to the same procedure and prophylactic care...
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28060696/acute-pancreatitis-and-posterior-reversible-encephalopathy-syndrome-a-case-report
#5
Vítor Magno Pereira, Luís Marote Correia, Tiago Rodrigues, Gorete Serrão Faria
The posterior reversible encephalopathy syndrome is a neurological syndrome characterized by headache, confusion, visual disturbances and seizures associated with identifiable areas of cerebral edema on imaging studies. The authors report the case of a man, 33 years-old, leukodermic with a history of chronic alcohol and tobacco consumption, who is admitted to the emergency department for epigastric pain radiating to the back and vomiting with about six hours of evolution and an intense holocranial headache for two hours...
September 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28055227/clinical-evaluation-of-post-operative-cerebral-infarction-in-traumatic-epidural-haematoma
#6
Suojun Zhang, Sheng Wang, Xueyan Wan, Shengwen Liu, Kai Shu, Ting Lei
BACKGROUND: Patients with traumatic epidural haematoma, undergoing the prompt and correct treatment, usually have favourable outcomes. However, secondary cerebral infarction may be life-threatening condition, as it is difficult to be identified before neurological impairment occurs. OBJECTIVE: To evaluate the clinical data of patients with traumatic EDH and assess potential risk factors for post-operative cerebral infarction. METHODS: The clinical data of patients with traumatic EDH were collected and analysed retrospectively...
January 5, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28052979/prevalence-incidence-and-mortality-of-stroke-in-china-results-from-a-nationwide-population-based-survey-of-480-687-adults
#7
Wenzhi Wang, Bin Jiang, Haixin Sun, Xiaojuan Ru, Dongling Sun, Linhong Wang, Limin Wang, Yong Jiang, Yichong Li, Yilong Wang, Zhenghong Chen, Shengping Wu, Yazhuo Zhang, David Wang, Yongjun Wang, Valery L Feigin
BACKGROUND: -China bears the biggest stroke burden in the world. However, little is known about the current prevalence, incidence, and mortality of stroke at the national level, and the trend in the last 30 years. METHODS: -In 2013 a nationally-representative door-to-door survey was conducted in 155 urban and rural centres in 31 provinces in China, totalling 480,687 adults aged ≥20 years. All stroke survivors were considered as prevalent stroke cases at the prevalent time (August 31, 2013)...
January 4, 2017: Circulation
https://www.readbyqxmd.com/read/28030939/evaluation-of-vcam-1-and-icam-1-concentration-and-values-of-global-tests-concerning-the-coagulation-system-of-patients-suffering-from-subarachnoid-haemorrage
#8
Abu-Sitta Al-Drawi, Michał Wiciński, Grzegorz Grześk, Katarzyna Szadujkis-Szadurska, Elżbieta Grześk, Mateusz Maciej Węclewicz, Agnieszka Michalska, Anna Czeczuk, Elżbieta Huk-Wieliczuk
INTRODUCTION: The term 'subarachnoid haemorrhage' (SAH) stands for bleeding into the subarachnoid space, regardless of its source. It may be of primary character when the source of bleeding is situated within the subarachnoid space. Subarachnoid haemorrhage is often described as spontaneous bleeding, mainly in order to differentiate it from post-traumatic bleeding. OBJECTIVE: The aim of the study was to evaluate the concentration of ICAM-1 and VCAM-1 in the blood of patients in the early phase following subarachnoid haemorrhage in terms of searching for markers useful in subarachnoid bleeding diagnostics and monitoring a patient's clinical state...
23, 2016: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/28028564/evolution-of-diffusion-tensor-imaging-parameters-after-acute-subarachnoid-haemorrhage-a-prospective-cohort-study
#9
Isabel Fragata, Patrícia Canhão, Marta Alves, Ana Luísa Papoila, Nuno Canto-Moreira
INTRODUCTION: Few studies assessed diffusion tensor imaging (DTI) changes in the acute phase of subarachnoid haemorrhage (SAH). We prospectively evaluated DTI parameters in the acute phase of SAH and 8-10 days after and analysed whether changes could be related to SAH severity or to the development of delayed cerebral ischemia (DCI). METHODS: Apparent diffusion coefficient (ADC) and fractional anisotropy (FA) changes over time were assessed in a prospective cohort of patients with acute SAH...
December 27, 2016: Neuroradiology
https://www.readbyqxmd.com/read/28017208/subjective-hearing-impairment-after-subarachnoid-haemorrhage-prevalence-and-risk-factors
#10
Erik M Vos, Paut Greebe, J M Anne Visser-Meily, Gabriel J E Rinkel, Mervyn D I Vergouwen
BACKGROUND: Sensorineural hearing impairment is a key symptom in patients with superficial siderosis of the central nervous system, a disease caused by chronic or intermittent haemorrhage into the subarachnoid space. We investigated the prevalence and risk factors of subjective hearing impairment after SAH. METHODS: We systematically interviewed all SAH patients admitted between June 2011 and December 2014, who were able to visit the SAH outpatient clinic six to eight weeks after hospital discharge...
January 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28007486/-trends-in-computed-tomography-characteristics-intracranial-pressure-monitoring-and-surgical-management-in-severe-traumatic-brain-injury-analysis-of-a-data-base-of-the-past-25-years-in-a-neurosurgery-department
#11
Pedro A Gómez, Ana M Castaño-León, David Lora, Santiago Cepeda, Alfonso Lagares
OBJECTIVE: To describe the radiological characteristics, surgical indications, procedures, and intracranial pressure monitoring of a representative cohort of severe traumatic brain injury (sTBI) cases collected over the past 25years, and to analyse the changes that have occurred by dividing the period into 3 equal time periods. METHODS: An observational cohort study was conducted on consecutive adult patients (>14years of age) with severe closed TBI (Glasgow Coma Scale score [GCS]≤8) who were admitted during the first 48hours after injury to the Hospital 12 de Octubre from 1987 to 2012...
December 19, 2016: Neurocirugía
https://www.readbyqxmd.com/read/28004163/treatment-of-cerebral-vasospasm-following-aneurysmal-subarachnoid-haemorrhage-a-systematic-review-and-meta-analysis
#12
Grégoire Boulouis, Marc Antoine Labeyrie, Jean Raymond, Christine Rodriguez-Régent, Anne Claire Lukaszewicz, Damien Bresson, Wagih Ben Hassen, Denis Trystram, Jean Francois Meder, Catherine Oppenheim, Olivier Naggara
OBJECTIVES: To examine the clinical outcome of aneurysmal subarachnoid haemorrhage (aSAH) patients exposed to cerebral vasospasm (CVS)-targeted treatments in a meta-analysis and to evaluate the efficacy of intra-arterial (IA) approaches in patients with severe/refractory vasospasm. METHODS: Randomised controlled trials, prospective and retrospective observational studies reporting clinical outcomes of aSAH patients exposed to CVS targeted treatments, published between 2006-2016 were searched using PubMed, EMBASE and the Cochrane Library...
December 21, 2016: European Radiology
https://www.readbyqxmd.com/read/27943077/outcome-and-prognostic-factors-after-delayed-second-subarachnoid-haemorrhage
#13
Nina Brawanski, Johannes Platz, Markus Bruder, Christian Senft, Joachim Berkefeld, Volker Seifert, Juergen Konczalla
BACKGROUND: Data of patients suffering from delayed second subarachnoid haemorrhage (SAH) after aneurysm treatment are still missing. Patients become clearly older than before. Thus, the risk suffering from a second delayed SAH rises. The aim of this study was to analyse clinical outcome and prognostic factors in patients after delayed second SAH. METHOD: From 1999 to 2013, 18 of 1,493 patients (1.2%) suffered from a second SAH. Clinical and radiological characteristics were entered into a prospective conducted database...
February 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/27931120/outcomes-of-csf-spectrophotometry-in-cases-of-suspected-subarachnoid-haemorrhage-with-negative-ct-two-years-retrospective-review-in-a-birmingham-hospital
#14
A Bakr, D Silva, R Cramb, G Flint, M Foroughi
AIM: The aim of this study was to evaluate the adherence to current guidelines for the investigation of suspected subarachnoid haemorrhage and the prevalence and outcome of computed tomography (CT)-negative aneurysmal subarachnoid haemorrhage. DESIGN: A retrospective review in a single large tertiary referral centre. SUBJECTS: A total of 796 patients, aged 16-90 years, who underwent lumbar puncture (LP) for suspected subarachnoid haemorrhage (SAH) following a negative or equivocal CT scan between January 2012 and November 2013 (23 months)...
December 8, 2016: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/27927709/spontaneous-aneurysmal-subarachnoid-haemorrhage-in-a-child-with-multiply-recurrent-posterior-fossa-juvenile-pilocytic-astrocytoma
#15
Dillon Y Chen, Michael L Levy, John Ross Crawford
No abstract text is available yet for this article.
December 7, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27927702/bedside-cerebral-microdialysis-monitoring-of-delayed-cerebral-hypoperfusion-in-comatose-patients-with-poor-grade-aneurysmal-subarachnoid-haemorrhage
#16
Camille Patet, Hervé Quintard, Jean-Baptiste Zerlauth, Thomas Maibach, Laurent Carteron, Tamarah Suys, Pierre Bouzat, David Bervini, Marc Levivier, Roy T Daniel, Philippe Eckert, Reto Meuli, Mauro Oddo
BACKGROUND: Delayed cerebral ischaemia (DCI) is frequent after poor grade aneurysmal subarachnoid haemorrhage (SAH). Owing to the limited accuracy of clinical examination, DCI diagnosis is often based on multimodal monitoring. We examined the value of cerebral microdialysis (CMD) in this setting. METHODS: 20 comatose SAH participants underwent CMD monitoring-for hourly sampling of cerebral extracellular lactate/pyruvate ratio (LPR) and glucose-and brain perfusion CT (PCT)...
December 7, 2016: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/27927658/aneurysmal-subarachnoid-hemorrhage-red-blood-cell-transfusion-and-outcome-sahara-a-pilot-randomised-controlled-trial-protocol
#17
Shane W English, D Fergusson, M Chassé, A F Turgeon, F Lauzier, D Griesdale, A Algird, A Kramer, A Tinmouth, C Lum, J Sinclair, S Marshall, D Dowlatshahi, A Boutin, G Pagliarello, L A McIntyre
INTRODUCTION: Anaemia is common in aneurysmal subarachnoid haemorrhage (aSAH) and is a potential critical modifiable factor affecting secondary injury. Despite physiological evidence and management guidelines that support maintaining a higher haemoglobin level in patients with aSAH, current practice is one of a more restrictive approach to transfusion. The goal of this multicentre pilot trial is to determine the feasibility of successfully conducting a red blood cell (RBC) transfusion trial in adult patients with acute aSAH and anaemia (Hb ≤100 g/L), comparing a liberal transfusion strategy (Hb ≤100 g/L) with a restrictive strategy (Hb ≤80 g/L) on the combined rate of death and severe disability at 12 months...
December 7, 2016: BMJ Open
https://www.readbyqxmd.com/read/27903205/predicting-neurological-deficit-severity-due-to-subarachnoid-haemorrhage-soluble-cd40-ligand-and-platelet-derived-growth-factor-bb
#18
Yoshitaka Kubo, Takahiro Koji, Jun Yoshida, Akira Ogawa, Kuniaki Ogasawara
BACKGROUND: Several biological markers can predict outcomes in patients with subarachnoid haemorrhage (SAH), but markers to predict neurological deficit severity in patients with SAH and poor neurological condition have not yet been established. Soluble CD40 ligand (sCD40L) and platelet-derived growth factor (PDGF) are related to the systemic inflammatory response. OBJECTIVE: In a prospective study, to investigate the relationship between clinical outcomes and blood test results in patients with SAH and severe neurological deficits...
December 2016: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/27895358/paediatric-traumatic-brain-injury-presentation-prognostic-indicators-and-outcome-analysis-from-a-tertiary-care-center-in-a-developing-country
#19
Badar Ujjan, Muhammad Waqas, Muhammad Babar Khan, Saqib Kamran Bakhshi, Muhammad Ehsan Bari
Traumatic brain injury (TBI) is the leading cause of morbidity and mortality in children worldwide. This study was conducted to report the presentation, management, outcomes and prognostic indicators in a large series of patients from a tertiary care centre in a developing country. It is a review of prospectively collected data of paediatric patients with TBI admitted at our centre between July 2010 and December 2013. A total of 291 patients with a mean age of 7.2±5.0 years were dichotomised into survivors and non-survivors, and variables were compared between the two groups...
October 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27895241/secular-pattern-of-aneurismal-rupture-with-the-lunar-cycle-and-season
#20
Jillian C Banfield, Mohamed Abdolell, Jai S Shankar
BACKGROUND: The lunar cycle and seasons may be associated with rates of rupture of intracranial aneurysms, but the literature is mixed. Studies of the association between the lunar cycle and rates of aneurysm rupture used the eight qualitative moon phases. The purpose of this study was to assess any association of aneurysm rupture with the lunar cycle and with the season. MATERIALS AND METHODS: We retrospectively reviewed all cases of subarachnoid haemorrhage secondary to ruptured intracranial aneurysm treated with endovascular coiling in our institution over a 10-year period...
November 28, 2016: Interventional Neuroradiology
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