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https://www.readbyqxmd.com/read/29037012/medical-treatment-of-intracranial-atherosclerosis-an-update
#1
REVIEW
Jong S Kim, Oh Young Bang
For patients with symptomatic intracranial atherosclerosis (ICAS), antithrombotic agents are the mainstay of therapy. Anticoagulation (warfarin) is not widely used since it is not more effective than aspirin and carries a high risk of bleeding. New oral anticoagulants are showing promise, but their use has not been investigated in appropriate clinical trials. Since the recurrent stroke risk is high with aspirin monotherapy, dual antiplatelets are considered in the early stage of symptomatic ICAS. Based on the Clopidogrel in High-Risk Patients with Acute Nondisabling Cerebrovascular Events (CHANCE) and Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) results, aspirin plus clopidogrel has been recommended...
September 2017: Journal of Stroke
https://www.readbyqxmd.com/read/29036970/-update-on-the-diagnosis-and-management-of-cardiac-sarcoidosis
#2
Q Zhu, X Q Hu, S H Zhou
No abstract text is available yet for this article.
September 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29036965/-the-mechanism-of-drug-resistance-in-acinetobacter-baumannii-and-updates-of-development-in-novel-antibiotics
#3
P He, S W Li, X Y Wan
No abstract text is available yet for this article.
October 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29036878/geometric-artifacts-reduction-for-cone-beam-ct-via-l0-norm-minimization-without-dedicated-phantoms
#4
Changcheng Gong, Yufang Cai, Li Zeng
For cone-beam computed tomography (CBCT), transversal shifts of the rotation center exist inevitably, which will result in geometric artifacts in CT images. In this work, we propose a novel geometric calibration method for CBCT, which can also be used in micro-CT. The symmetry property of the sinogram is used for the first calibration, and then L0-norm of the gradient image from the reconstructed image is used as the cost function to be minimized for the second calibration. An iterative search method is adopted to pursue the local minimum of the L0-norm minimization problem...
October 10, 2017: Journal of X-ray Science and Technology
https://www.readbyqxmd.com/read/29036845/sexual-concerns-after-spinal-cord-injury-an-update-on-management
#5
Marcalee Sipski Alexander, Carrie Mlynarczyk Aisen, Sterling Morrison Alexander, Mindy Lipson Aisen
BACKGROUND: Spinal Cord Injury (SCI) causes neurological impairment with resultant neurogenic sexual dysfunction which can compound preexisting psychological and medical sexual concerns. Understanding these concerns is important in managing the lifelong needs of persons with SCIs. OBJECTIVES: To provide an overview of the impact of SCI on sexuality along with a framework for treatment of sexual concerns. To briefly review male infertility and its treatments and pregnancy in females after SCI...
October 11, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/29036756/acupuncture-or-acupressure-for-induction-of-labour
#6
REVIEW
Caroline A Smith, Mike Armour, Hannah G Dahlen
BACKGROUND: This is one of a series of reviews of methods of cervical ripening and labour induction. The use of complementary therapies is increasing. Women may look to complementary therapies during pregnancy and childbirth to be used alongside conventional medical practice. Acupuncture involves the insertion of very fine needles into specific points of the body. Acupressure is using the thumbs or fingers to apply pressure to specific points. The limited observational studies to date suggest acupuncture for induction of labour has no known adverse effects to the fetus, and may be effective...
October 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29036752/breast-cancer-screening-updated-recommendations-of-the-brazilian-college-of-radiology-and-diagnostic-imaging-brazilian-breast-disease-society-and-brazilian-federation-of-gynecological-and-obstetrical-associations
#7
Linei Augusta Brolini Dellê Urban, Luciano Fernandes Chala, Selma di Pace Bauab, Marcela Brisighelli Schaefer, Radiá Pereira Dos Santos, Norma Medicis de Albuquerque Maranhão, Ana Lucia Kefalas, José Michel Kalaf, Carlos Alberto Pecci Ferreira, Ellyete de Oliveira Canella, João Emílio Peixoto, Heverton Leal Ernesto de Amorim, Helio Sebastião Amâncio de Camargo Junior
No abstract text is available yet for this article.
October 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/29036747/prevention-of-multidrug-resistant-infections-from-contaminated-duodenoscopes-position-statement-of-the-european-society-of-gastrointestinal-endoscopy-esge-and-european-society-of-gastroenterology-nurses-and-associates-esgena
#8
Ulrike Beilenhoff, Holger Biering, Reinhard Blum, Jadranka Brljak, Monica Cimbro, Jean-Marc Dumonceau, Cesare Hassan, Michael Jung, Christiane Neumann, Michael Pietsch, Lionel Pineau, Thierry Ponchon, Stanislav Rejchrt, Jean-François Rey, Verona Schmidt, Jayne Tillett, Jeanin van Hooft
Patients should be informed about the benefits and risks of endoscopic retrograde cholangiopancreatography (ERCP)Only specially trained and competent personnel should carry out endoscope reprocessing.Manufacturers of duodenoscopes should provide detailed instructions on how to use and reprocess their equipment.In the case of modifications to their equipment, manufacturers should provide updated instructions for use.Detailed reprocessing protocols based on the manufacturer's instructions for use should clearly lay out the different reprocessing steps necessary for each endoscope model...
October 16, 2017: Endoscopy
https://www.readbyqxmd.com/read/29036684/yeastract-an-upgraded-database-for-the-analysis-of-transcription-regulatory-networks-in-saccharomyces-cerevisiae
#9
Miguel C Teixeira, Pedro T Monteiro, Margarida Palma, Catarina Costa, Cláudia P Godinho, Pedro Pais, Mafalda Cavalheiro, Miguel Antunes, Alexandre Lemos, Tiago Pedreira, Isabel Sá-Correia
The YEAst Search for Transcriptional Regulators And Consensus Tracking (YEASTRACT-www.yeastract.com) information system has been, for 11 years, a key tool for the analysis and prediction of transcription regulatory associations at the gene and genomic levels in Saccharomyces cerevisiae. Since its last update in June 2017, YEASTRACT includes approximately 163000 regulatory associations between transcription factors (TF) and target genes in S. cerevisiae, based on more than 1600 bibliographic references; it also includes 247 specific DNA binding consensus recognized by 113 TFs...
September 25, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29036653/mircarta-a-central-repository-for-collecting-mirna-candidates
#10
Christina Backes, Tobias Fehlmann, Fabian Kern, Tim Kehl, Hans-Peter Lenhof, Eckart Meese, Andreas Keller
The continuous increase of available biological data as consequence of modern high-throughput technologies poses new challenges for analysis techniques and database applications. Especially for miRNAs, one class of small non-coding RNAs, many algorithms have been developed to predict new candidates from next-generation sequencing data. While the amount of publications describing novel miRNA candidates keeps steadily increasing, the current gold standard database for miRNAs - miRBase - has not been updated since June 2014...
September 25, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29036632/mapping-compulsivity-in-the-dsm-5-obsessive-compulsive-and-related-disorders-cognitive-domains-neural-circuitry-and-treatment
#11
Naomi A Fineberg, Annemieke M Apergis-Schoute, M Matilde Vaghi, Paula Banca, Claire M Gillan, Valerie Voon, Samuel R Chamberlain, Cinosi Eduardo, Reid Jemma, Sonia Shahper, Edward T Bullmore, Barbara J Sahakian, Trevor W Robbins
Compulsions are repetitive, stereotyped thoughts and behaviors designed to reduce harm. Growing evidence suggests that the neurocognitive mechanisms mediating behavioural inhibition (motor inhibition, cognitive inflexibility) reversal learning and habit formation (shift from goal-directed to habitual responding) contribute toward compulsive activity in a broad range of disorders. In obsessive compulsive disorder (OCD), distributed network perturbation appears focussed around the pre-frontal cortex, caudate, putamen and associated neuro-circuitry...
September 23, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29036542/database-resources-of-the-big-data-center-in-2018
#12
(no author information available yet)
The BIG Data Center at Beijing Institute of Genomics (BIG) of the Chinese Academy of Sciences provides freely open access to a suite of database resources in support of worldwide research activities in both academia and industry. With the vast amounts of omics data generated at ever-greater scales and rates, the BIG Data Center is continually expanding, updating and enriching its core database resources through big-data integration and value-added curation, including BioCode (a repository archiving bioinformatics tool codes), BioProject (a biological project library), BioSample (a biological sample library), Genome Sequence Archive (GSA, a data repository for archiving raw sequence reads), Genome Warehouse (GWH, a centralized resource housing genome-scale data), Genome Variation Map (GVM, a public repository of genome variations), Gene Expression Nebulas (GEN, a database of gene expression profiles based on RNA-Seq data), Methylation Bank (MethBank, an integrated databank of DNA methylomes), and Science Wikis (a series of biological knowledge wikis for community annotations)...
October 3, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29036511/the-national-radon-archive-as-a-useful-tool-for-developing-and-updating-the-national-radon-action-plan
#13
F Bochicchio, S Antignani, C Carpentieri, M Ampollini, B Caccia, S Pozzi, G Venoso
International recommendations and regulations require developing of National Radon Action Plans (NRAPs) to effectively manage the protection of workers and population from radon exposure. In Italy, a NRAP was published in 2002 and several activities have been carried out in this framework. Information and data regarding these and previous activities have been collected in a National Radon Archive (NRA). Activities carried out by institutionally involved institutes and agencies include several national and regional surveys, involving more than 50 000 indoor environments (dwellings, schools and workplaces), and remedial actions performed in ~350 buildings, largely in schools...
September 29, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/29036500/glioma-cpg-island-methylator-phenotype-g-cimp-biological-and-clinical-implications
#14
Tathiane M Malta, Camila F de Souza, Thais S Sabedot, Tiago C Silva, Maritza Q S Mosella, Steven N Kalkanis, James Snyder, Ana Valeria B Castro, Houtan Noushmehr
Gliomas are a heterogeneous group of brain tumors with distinct biological and clinical properties. Despite advances in surgical techniques and clinical regimens, treatment of high-grade glioma remains challenging and carries dismal rates of therapeutic success and overall survival. Challenges include the molecular complexity of gliomas, as well as inconsistencies in histopathological grading, resulting in an inaccurate prediction of disease progression and failure in the use of standard therapy. The updated 2016 World Health Organization (WHO) classification of tumors of the central nervous system reflects a refinement of tumor diagnostics by integrating the genotypic and phenotypic features, thereby narrowing the defined subgroups...
September 26, 2017: Neuro-oncology
https://www.readbyqxmd.com/read/29036436/prevalence-of-adult-overweight-and-obesity-in-20-european-countries-2014
#15
Adilson Marques, Miguel Peralta, Ana Naia, Nuno Loureiro, Margarida Gaspar de Matos
Background: Monitoring obesity and overweight prevalence is important for assessing interventions aimed at preventing or reducing the burden of obesity. This study aimed to provide current data regarding the prevalence of overweight and obesity of adults, from 20 European countries. Methods: Participants were 34 814 (16 482 men) adults with mean age 50.8 ± 17.7. Data from European Social Survey round 7, 2014, were analysed. Body mass index (BMI) was calculated from self-reported height and weight...
September 23, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/29036404/the-value-of-prior-knowledge-in-machine-learning-of-complex-network-systems
#16
Dana Ferranti, David Krane, David Craft
Motivation: Our overall goal is to develop machine-learning approaches based on genomics and other relevant accessible information for use in predicting how a patient will respond to a given proposed drug or treatment. Given the complexity of this problem, we begin by developing, testing and analyzing learning methods using data from simulated systems, which allows us access to a known ground truth. We examine the benefits of using prior system knowledge and investigate how learning accuracy depends on various system parameters as well as the amount of training data available...
July 7, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29036392/update-from-the-advisory-committee-on-immunization-practices
#17
Sean T O'Leary, David W Kimberlin
The Advisory Committee on Immunization Practices (ACIP), a group of medical and public health experts, meets 3 times per year to develop recommendations for vaccine use in the United States. The group has 15 voting members, and each member's term is 4 years. ACIP members and Centers for Disease Control and Prevention (CDC) staff discuss the epidemiology of vaccine-preventable diseases and vaccine research, effectiveness, safety data, and clinical trial results. Representatives from the American Academy of Pediatrics (Carrie L...
September 25, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29036351/mirandola-2017-a-curated-knowledge-base-of-non-invasive-biomarkers
#18
Francesco Russo, Sebastiano Di Bella, Federica Vannini, Gabriele Berti, Flavia Scoyni, Helen V Cook, Alberto Santos, Giovanni Nigita, Vincenzo Bonnici, Alessandro Laganà, Filippo Geraci, Alfredo Pulvirenti, Rosalba Giugno, Federico De Masi, Kirstine Belling, Lars J Jensen, S Ren Brunak, Marco Pellegrini, Alfredo Ferro
miRandola (http://mirandola.iit.cnr.it/) is a database of extracellular non-coding RNAs (ncRNAs) that was initially published in 2012, foreseeing the relevance of ncRNAs as non-invasive biomarkers. An increasing amount of experimental evidence shows that ncRNAs are frequently dysregulated in diseases. Further, ncRNAs have been discovered in different extracellular forms, such as exosomes, which circulate in human body fluids. Thus, miRandola 2017 is an effort to update and collect the accumulating information on extracellular ncRNAs that is spread across scientific publications and different databases...
September 25, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29036085/local-receptive-field-constrained-stacked-sparse-autoencoder-for-classification-of-hyperspectral-images
#19
Xiaoqing Wan, Chunhui Zhao
As a competitive machine learning algorithm, the stacked sparse autoencoder (SSA) has achieved outstanding popularity in exploiting high-level features for classification of hyperspectral images (HSIs). In general, in the SSA architecture, the nodes between adjacent layers are fully connected and need to be iteratively fine-tuned during the pretraining stage; however, the nodes of previous layers further away may be less likely to have a dense correlation to the given node of subsequent layers. Therefore, to reduce the classification error and increase the learning rate, this paper proposes the general framework of locally connected SSA; that is, the biologically inspired local receptive field (LRF) constrained SSA architecture is employed to simultaneously characterize the local correlations of spectral features and extract high-level feature representations of hyperspectral data...
June 1, 2017: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/29036020/novel-methods-for-device-and-adherence-monitoring-in-asthma
#20
Matteo Bonini, Omar S Usmani
PURPOSE OF REVIEW: The article aims to provide an updated and evidence-based review of the innovative electronic health interventions to monitor and improve inhaler technique and adherence to recommended therapy in asthma. RECENT FINDINGS: Out of the 290 articles identified by the search strategy, 23 manuscripts fulfilled the review inclusion criteria. Included studies mainly addressed m-health, electronic reminders, telemedicine, and inhaler tracker interventions...
October 13, 2017: Current Opinion in Pulmonary Medicine
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