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Glaucoma drainage device

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https://www.readbyqxmd.com/read/28319643/grooved-glaucoma-drainage-devices-that-continuously-deliver-cyclosporine-a-decrease-postsurgical-scar-formation-in-rabbit-eyes
#1
Zhaoxing Dai, Xiaobo Yu, Jianguo Sun, Xinghuai Sun
Purpose: To study the functional outcomes of filtration surgery by implanting improved glaucoma drainage devices (GDDs) comprising surface grooves and a composite coating of cyclosporine A (CsA) and PLGA in experimental rabbit eyes. Methods: Improved GDDs were designed and prepared by modifying normal GDD with surface grooves and a CsA-PLGA composite coating. Normal GDDs, grooved GDDs (G-GDDs), and G-GDDs with a CsA-PLGA composite coating (CsA@G-GDD) were implanted into 18 rabbit eyes (six eyes per group)...
March 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28303370/comparison-of-graft-survival-following-penetrating-keratoplasty-and-descemet-s-stripping-endothelial-keratoplasty-in-eyes-with-a-glaucoma-drainage-device
#2
Shawn M Iverson, Oriel Spierer, George C Papachristou, William J Feuer, Wei Shi, David S Greenfield, Terrence P O'Brien
PURPOSE: To compare corneal graft survival rates after penetrating keratoplasty (PK) and Descemet's stripping endothelial keratoplasty (DSEK) in patients with a glaucoma drainage device (GDD) or medically managed glaucoma. METHODS: A retrospective chart review was conducted on consecutive patients who underwent primary PK or primary DSEK. Inclusion criteria consisted of eyes with a diagnosis of glaucoma prior to corneal transplantation and a minimum of 6 months of follow-up...
March 16, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28301639/association-of-repeated-intravitreous-bevacizumab-injections-with-risk-for-glaucoma-surgery
#3
Brennan D Eadie, Mahyar Etminan, Bruce C Carleton, David A Maberley, Frederick S Mikelberg
Importance: Intravitreous injections of anti-vascular endothelial growth factor (VEGF) agents are associated with a sustained increase in intraocular pressure. This sustained elevated intraocular pressure could lead to higher rates of glaucoma surgery to lower this pressure. Objective: To determine the risk of glaucoma surgery following repeated intravitreous bevacizumab injections. Design, Setting, Participants: This nested, case-control study acquired and analyzed data from large, population-based, linked health databases supported by the British Columbia Ministry of Health in Canada...
March 16, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28301490/a-novel-flexible-microfluidic-meshwork-to-reduce-fibrosis-in-glaucoma-surgery
#4
Behzad Amoozgar, Xiaoling Wei, Jun Hui Lee, Michele Bloomer, Zhengtuo Zhao, Paul Coh, Fei He, Lan Luan, Chong Xie, Ying Han
PURPOSE/RELEVANCE: Fibrosis and hence capsule formation around the glaucoma implants are the main reasons for glaucoma implant failure. To address these issues, we designed a microfluidic meshwork and tested its biocompatibility in a rabbit eye model. The amount of fibrosis elicited by the microfluidic meshwork was compared to the amount elicited by the plate of conventional glaucoma drainage device. METHODS: Six eyes from 3 New Zealand albino rabbits were randomized to receive either the novel microfluidic meshwork or a plate of Ahmed glaucoma valve model PF7 (AGV PF7)...
2017: PloS One
https://www.readbyqxmd.com/read/28286307/strabismus-surgery-outcomes-in-eyes-with-glaucoma-drainage-devices
#5
Carla J Osigian, Kara M Cavuoto, Julia D Rossetto, Mohamed Sayed, Sara Grace, Ta C Chang, Hilda Capo
PURPOSE: To report strabismus surgery outcomes in eyes with prior implantation of glaucoma drainage devices (GDD). METHODS: The medical records of patients who underwent strabismus surgery for ocular misalignment that developed after implantation of a GDD over a 13-year period at a single institution were examined retrospectively. Patient characteristics, deviation types, preoperative measurements, surgical procedures, and postoperative measurements were analyzed...
March 9, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28276751/development-of-a-laser-controlled-device-to-modulate-intraocular-pressure
#6
REVIEW
Jeffrey L Olson, Ramanath Bhandari, Sergio Groman-Lupa, Daniela Santos-Cantu, Raul Velez-Montoya
The current standard of treatment for glaucoma is trabeculectomy. The use of glaucoma drainage devices has increased in recent years since its efficacy and safety was established as it provides an alternative surgical option. A downfall of these devices is the lack of proper flow rate control. Areas covered: In this paper we describe a glaucoma drainage device regulator that has already been protoyped and undergone initial testing. It consists of an implantable device with a semipermeable membrane that is used during glaucoma surgery and can be opened with either thermal or photodisruptive laser to adjust the amount of flow precisely and non-invasively, addressing the current difficulties of glaucoma surgeries...
March 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28269212/low-cost-rapid-prototyping-of-liquid-crystal-polymer-based-magnetic-microactuators-for-glaucoma-drainage-devices
#7
Hyunsu Park, Simon John, Hyowon Lee
Glaucoma is one of the leading causes of blindness in the world. Although there is no cure for glaucoma, pharmaceutical or surgical interventions are known to delay the progression of this debilitating disease. In recent years, implantation of glaucoma drainage devices (GDD) have increased due to their ability to manage IOP better than other therapeutic approaches. However, only 50% of the implanted devices remain functional after 5 years often due to biofouling. Here, we report our latest progress towards developing self-clearing GDDs using integrated magnetic microactuators...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28254440/combined-vitrectomy-and-glaucoma-drainage-device-implantation-surgical-approach-for-complex-pediatric-glaucomas
#8
Cem Ozgonul, Cagri G Besirli, Brenda L Bohnsack
PURPOSE: To evaluate efficacy of combined vitrectomy with posteriorly placed glaucoma drainage device (GDD) in lowering intraocular pressure (IOP) in children. METHODS: The medical records of children who underwent vitrectomy with posteriorly placed GDD were reviewed retrospectively. Patients with a minimum of 6 months' follow-up were included. The first eye operated on for each patient was analyzed. Success was defined as IOP of 5-20 mm Hg and no additional IOP-lowering surgery or visually devastating complications...
February 27, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28227442/low-cost-rapid-prototyping-of-liquid-crystal-polymer-based-magnetic-microactuators-for-glaucoma-drainage-devices
#9
Hyunsu Park, Simon John, Hyowon Lee, Hyunsu Park, Simon John, Hyowon Lee, Simon John, Hyowon Lee, Hyunsu Park
Glaucoma is one of the leading causes of blindness in the world. Although there is no cure for glaucoma, pharmaceutical or surgical interventions are known to delay the progression of this debilitating disease. In recent years, implantation of glaucoma drainage devices (GDD) have increased due to their ability to manage IOP better than other therapeutic approaches. However, only 50% of the implanted devices remain functional after 5 years often due to biofouling. Here, we report our latest progress towards developing self-clearing GDDs using integrated magnetic microactuators...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28176011/implantation-of-a-second-glaucoma-drainage-device
#10
Brian A Francis, Rodrigo A B Fernandes, Handan Akil, Vikas Chopra, Bruno Diniz, James Tan, Alex Huang
PURPOSE: To evaluate success rates in controlling intraocular pressure (IOP) after implantation of a second glaucoma drainage device (GDD) with a Baerveldt glaucoma implant in patients with refractory glaucoma, with a secondary aim of reducing the need for postoperative glaucoma medications. MATERIAL AND METHODS: This retrospective, noncomparative, interventional study included patients undergoing a second GDD for uncontrolled glaucoma from a tertiary care glaucoma service...
February 7, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28144751/glaucoma-drainage-device-surgery-in-children-and-adults-a-comparative-study-of-outcomes-and-complications
#11
Achilleas Mandalos, Velota Sung
PURPOSE: To compare the postoperative outcomes and complications of glaucoma drainage device (GDD) surgery in pediatric (<18 years old) and adult patients. METHODS: Retrospective, comparative study including all patients who underwent Baervedlt or Molteno device surgery by the same surgeon. Success criteria included postoperative intraocular pressure (IOP) between 6 and 21 mmHg and a 20% reduction from baseline. RESULTS: Fifty-two children (69 eyes) and 130 adults (145 eyes) were included...
February 1, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28139154/safety-and-efficacy-of-a-membrane-tube-type-glaucoma-shunt-device-an-animal-trial
#12
Dai Woo Kim, Young Hoon Hwang, Byung Heon Ahn, Eun-Kyung Lee, Chang-Sik Kim
PURPOSE: To evaluate the safety and efficacy of a membrane-tube-type glaucoma shunt device (MT-device), which was developed to control intraocular pressure (IOP) with a lower chance of complications than conventional glaucoma surgery, in a rabbit model. MATERIALS AND METHODS: The MT-device consists of an expanded polytetrafluoroethylene membrane (thickness 0.2 mm, area 2.5 × 2.5 mm(2)) and a tube (internal diameter 76 µm, external diameter 175.5 µm, length 7 mm) attached to the membrane...
January 31, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28138212/retrospective-comparison-of-intermediate-term-efficacy-of-350-mm-2-glaucoma-drainage-implants-and-medium-sized-230-250-mm-2-implants
#13
Alissa M Meyer, Cooper D Rodgers, Baiming Zou, Nicole C Rosenberg, Aaron D Webel, Mark B Sherwood
AIM: To compare the intermediate-term efficacy of a large surface area Baerveldt 350 mm(2) glaucoma drainage device (GDD) with medium surface area implants (Baerveldt 250 mm(2) and Molteno 3, 230, or 245 mm(2)). DESIGN: This is a retrospective, nonrandomized comparative trial. MATERIALS AND METHODS: A total of 94 eyes of 94 patients of mixed glaucoma diagnoses without any prior glaucoma surgical procedures and who had undergone a glaucoma drainage implant surgery with either a large Baerveldt 350 mm(2) GDD or a medium-sized GDD (Baerveldt 250 mm(2) or Molteno 230 or 245 mm(2)) were reviewed for intraocular pressure (IOP), number of glaucoma medications, and visual acuity (VA) preoperatively, and at 1, 2, and 3 years postprocedure...
January 2017: Journal of Current Glaucoma Practice
https://www.readbyqxmd.com/read/28138210/relationship-between-glaucoma-drainage-device-size-and-intraocular-pressure-control-does-size-matter
#14
EDITORIAL
Cooper D Rodgers, Alissa M Meyer, Mark B Sherwood
There is ambiguity in the literature regarding whether a larger glaucoma drainage device (GDD) achieves a lower long-term intraocular pressure (IOP). There is some evidence on both sides, but overall there seems to be an optimal surface area of approximately 200-250 mm(2) beyond which there may be little advantage to increasing the plate size for most patients. HOW TO CITE THIS ARTICLE: Rodgers CD, Meyer AM, Sherwood MB. Relationship between Glaucoma Drainage Device Size and Intraocular Pressure Control: Does Size Matter? J Curr Glaucoma Pract 2017;11(1):1-2...
January 2017: Journal of Current Glaucoma Practice
https://www.readbyqxmd.com/read/28134460/surgical-outcomes-of-trabeculectomy-and-glaucoma-drainage-implant-for-uveitic-glaucoma-and-relationship-with-uveitis-activity
#15
Hye Jin Kwon, Yu Xiang George Kong, Lingwei William Tao, Lyndell L Lim, Keith R Martin, Catherine Green, Jonathan Ruddle, Jonathan G Crowston
IMPORTANCE: This study provides ophthalmologists who manage uveitic glaucoma with important information on factors that can affect the success of surgical management of this challenging disease. BACKGROUND: This study examines surgical outcomes of trabeculectomy and glaucoma device implant (GDI) surgery for uveitic glaucoma, in particular the effect of uveitis activity on surgical outcomes. DESIGN: Retrospective chart review at a tertiary institution...
January 30, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28118286/viscoelastic-assisted-drainage-of-suprachoroidal-hemorrhage-associated-with-seton-device-in-glaucoma-filtering-surgery
#16
Shree K Kurup, Jedediah I McClintic, John C Allen, Brandon J Baartman, Michael M Altaweel, Sunir J Garg, Hugo Quiroz-Mercado
PURPOSE: The purpose of this article is to describe a novel surgical technique for the management of large suprachoroidal hemorrhages associated with the insertion of glaucoma seton devices. METHODS: In this interventional case series, the authors describe six eyes of six patients who had management of suprachoroidal hemorrhage with pars plana choroidal drainage along with simultaneous insertion of viscoelastic into the posterior segment. All patients had a median of 8-month postoperative follow-up...
February 2017: Retina
https://www.readbyqxmd.com/read/28118203/evaluation-of-the-efficacy-and-safety-of-the-new-susanna-glaucoma-drainage-device-in-refractory-glaucomas-short-term-results
#17
Luis G Biteli, Tiago S Prata, Carolina P B Gracitelli, Fábio N Kanadani, Flávia Villas Boas, Marcelo Hatanaka, Augusto Paranhos Junior
PURPOSE: To assess the efficacy and safety of the new Susanna glaucoma drainage device (SGDD) in patients with neovascular and refractory glaucomas. MATERIALS AND METHODS: In this prospective study, patients with neovascular glaucoma or refractory glaucomas (defined as eyes with previous trabeculectomy failure) were enrolled. All eyes had to have intraocular pressure (IOP) above 21 mm Hg despite maximum tolerated topical medication, or recent documentation of anatomic and/or functional progression...
January 23, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28104502/staying-away-from-the-optic-nerve-a-formula-for-modifying-glaucoma-drainage-device-surgery-in-pediatric-and-other-small-eyes
#18
Milica A Margeta, Anthony N Kuo, Alan D Proia, Sharon F Freedman
PURPOSE: To provide guidelines for safe implantation of glaucoma drainage devices (GDDs) in small and pediatric eyes to avoid contact between the optic nerve (ON) and the posterior edge of the GDD plate. METHODS: We developed a formula for calculating limbus-to-ON distance to estimate the available "real estate" for GDD placement in small eyes. The formula was validated using eyes of pediatric decedents undergoing clinical autopsy, with axial lengths (AL) of 15-24 mm...
February 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28098579/xen-gel-stent-internal-ostium-occlusion-ab-interno-revision
#19
Nuno Pinto Ferreira, Luis Abegão Pinto, Carlos Marques-Neves
Minimally invasive glaucoma surgery aims to provide a safer and less-invasive means of reducing IOP compared with traditional surgery, with the goal of reducing the need for topical medications. The XEN gel stent is an ab-interno minimally invasive glaucoma surgery device that approaches intraocular pressure reduction by creating a subconjunctival drainage pathway. As with any new device there is lack of experience and knowledge about its long-term results in terms of efficacy, technique, and complications...
January 16, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/27977576/outcome-of-primary-trabeculotomy-ab-interno-trabectome-surgery-in-patients-with-steroid-induced-glaucoma
#20
MULTICENTER STUDY
Philip Ngai, Grace Kim, Garrick Chak, Ken Lin, Masahiro Maeda, Sameh Mosaed
To determine the efficacy and safety of Trabectome surgery on patients with steroid response, ranging from ocular hypertension refractory to maximal medical therapy to the development of steroid-induced glaucoma.A nonrandomized, nonblinded, retrospective study of 20 subjects with steroid response was conducted. All 20 eyes underwent Trabectome surgery alone. Nine subjects had steroid response with unremarkable visual field, 3 had mild steroid-induced glaucoma, and 8 had advanced steroid-induced glaucoma. Outcome measures included intraocular pressure (IOP), number of glaucoma medications, need for secondary glaucoma surgery, and steroid regimen...
December 2016: Medicine (Baltimore)
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