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https://www.readbyqxmd.com/read/29164939/using-cbpr-to-decrease-health-disparities-in-a-suburban-latino-neighborhood
#1
Maren J Coffman, Brisa Urquieta de Hernandez, Heather A Smith, Andrew McWilliams, Yhenneko J Taylor, Hazel Tapp, Johanna Claire Schuch, Owen Furuseth, Michael Dulin
INTRODUCTION: This project tested the feasibility of using a community-based participatory research (CBPR) approach to deliver health and social resources in two high-risk, suburban neighborhoods. METHOD: An established research network was used to engage stakeholders to design and deliver a neighborhood-based intervention targeting a Latino immigrant population. The intervention provided screenings for hypertension, diabetes, and depression; primary care provider visits; and information about navigating health care delivery systems and related community-based resources...
September 2017: Hispanic Health Care International: the Official Journal of the National Association of Hispanic Nurses
https://www.readbyqxmd.com/read/29154246/do-we-need-changes-in-the-organization-of-training-in-the-hernia-treatment-in-poland-a-survey-on-the-acknowledgment-of-the-recommendations-of-international-hernia-societies-by-surgeons
#2
Kryspin Mitura, Stanisław Dąbrowiecki, Maciej Śmietański, Andrzej Matyja
In the therapy of an inguinal hernia, there is a huge variety in the way of treating and the choice of surgical technique. Practice shows that the intraoperative improvisation and surgeons' own modifications of the original techniques have become part of routine procedure. No mandatory hernia registration system causes the actual detailed herniology status in our country remains unknown. The aim of the study was to summarize the results of a survey on knowledge of a hernia according to the standards developed by international hernia societies compared with everyday clinical practice...
October 31, 2017: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/29144544/effects-of-nicotine-on-alcohol-drinking-in-female-mice-selectively-bred-for-high-or-low-alcohol-preference
#3
Marcus M Weera, Molly A Fields, Danielle N Tapp, Nicholas J Grahame, Julia A Chester
BACKGROUND: Studies show that repeated nicotine use associates with high alcohol consumption in humans, and that nicotine exposure sometimes increases alcohol consumption in animal models. However, the relative roles of genetic predisposition to high alcohol consumption, the alcohol drinking patterns, and the timing of nicotine exposure both with respect to alcohol drinking and developmental stage remain unclear. The studies here manipulated all these variables, using mice selectively bred for differences in free-choice alcohol consumption to elucidate the role of genetics and nicotine exposure in alcohol consumption behaviors...
November 16, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29141745/histology-and-serum-cytokine-responses-in-an-imported-rickettsia-slovaca-infection-germany
#4
Dennis Tappe, Nina Booken, Almut Böer-Auer, Jessica Rauch, Stefan Schmiedel, Kristian Reich
Rickettsia slovaca, a spotted fever group rickettsial pathogen, causes a syndrome consisting of scalp eschar and neck lymphadenopathy following tick bites. We analyzed the histologic skin reaction in the eschar, showing a prominent eosinophilic infiltration, as well as the presence of B lymphocytes and CD4- and CD8-positive T cells. Examination of the serum cytokine responses over time demonstrated an initial proinflammatory cytokine elevation followed by normalization.
October 23, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29124407/educational-system-based-on-the-tapp-checklist-improves-the-performance-of-novices-a-multicenter-randomized-trial
#5
Saseem Poudel, Yo Kurashima, Kimitaka Tanaka, Hiroshi Kawase, Yoichi M Ito, Fumitaka Nakamura, Toshiaki Shichinohe, Satoshi Hirano
BACKGROUND: Despite recent developments in surgical education, obstacles including inadequate budget, limited human resources, and a scarcity of time have limited its widespread adoption. To provide systematic training for laparoscopic inguinal hernia repair, we had previously developed and validated a checklist to evaluate the recorded performance of transabdominal preperitoneal (TAPP) repair. We had also developed an educational system that included didactic materials based on the TAPP checklist and incorporated remote evaluation and feedback system...
November 9, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29112438/-oligo-thiophene-functionalized-tetraazaperopyrenes-donor-acceptor-dyes-and-ambipolar-organic-semiconductors
#6
Lena Hahn, André Hermannsdorfer, Benjamin Günther, Tobias Wesp, Bastian Bühler, Ute Zschieschang, Hubert Wadepohl, Hagen Klauk, Lutz H Gade
Tetraazaperopyrenes (TAPPs) have been functionalized with thiophene and terthiophene units of different architecture resulting in a variety of organic donor-acceptor (D-A) compounds. The influence of the connection of the thiophenes to the TAPP core on their structural, photophysical and electrochemical properties has been studied in detail by a combination of X-ray crystallography, UV/Vis and fluorescence spectroscopy as well as cyclic voltammetry, which allowed the establishment of structure-property relationships...
November 7, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/29110041/-unusual-intraoperative-cystic-findings-in-laparoscopic-hernioplasty-tapp-for-scrotal-hernia
#7
B Nickel, B Kraft
No abstract text is available yet for this article.
November 6, 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/29075973/seroma-following-transabdominal-preperitoneal-patch-plasty-tapp-incidence-risk-factors-and-preventive-measures
#8
F Köckerling, R Bittner, D Adolf, R Fortelny, H Niebuhr, F Mayer, C Schug-Pass
BACKGROUND: The reported range of seroma formation in the literature after TEP repair is between 0.5 and 12.2% and for TAPP between 3.0 and 8.0%. Significant clinical factors associated with seroma formation include old age, a large hernia defect, an extension of the hernia sac into the scrotum, as well as the presence of a residual indirect sac. Seroma formation is a frequent complication of laparoendoscopic mesh repair of moderate to large-size direct (medial) inguinal hernia defects...
October 26, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29075969/what-are-the-influencing-factors-for-chronic-pain-following-tapp-inguinal-hernia-repair-an-analysis-of-20-004-patients-from-the-herniamed-registry
#9
H Niebuhr, F Wegner, M Hukauf, M Lechner, R Fortelny, R Bittner, C Schug-Pass, F Köckerling
BACKGROUND: In inguinal hernia repair, chronic pain must be expected in 10-12% of cases. Around one-quarter of patients (2-4%) experience severe pain requiring treatment. The risk factors for chronic pain reported in the literature include young age, female gender, perioperative pain, postoperative pain, recurrent hernia, open hernia repair, perioperative complications, and penetrating mesh fixation. This present analysis of data from the Herniamed Hernia Registry now investigates the influencing factors for chronic pain in male patients after primary, unilateral inguinal hernia repair in TAPP technique...
October 26, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29075859/transabdominal-pre-peritoneal-versus-open-repair-for-primary-unilateral-inguinal-hernia-a-meta-analysis
#10
James J Wu, Joshua A Way, Guy D Eslick, Michael R Cox
BACKGROUND: Recent NICE guidelines recommend open surgical approaches for the treatment of primary unilateral inguinal hernias. However, many surgeons perform a laparoscopic approach based on the advantages of less post-operative pain and faster recovery. Our aim was to examine current evidence comparing transabdominal pre-peritoneal (TAPP) laparoscopic repair and open surgical repair for primary inguinal hernias. METHODS: A systematic search of six electronic databases was conducted for randomised controlled trials (RCTs) comparing TAPP and open repair for primary unilateral inguinal hernia...
October 11, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29072828/microtubular-self-assembly-of-covalent-organic-frameworks
#11
Bappaditya Gole, Vladimir Stepanenko, Sabrina Rager, Matthias Grüne, Dana D Medina, Thomas Bein, Frank Würthner, Florian Beuerle
Despite significant progress in the synthesis of covalent organic frameworks (COFs), reports on a precise construction of template-free nano- and microstructures for such materials have been rare. In search of dye-containing porous materials, a novel conjugated framework DPP-TAPP-COF with enhanced absorption capability up to 800 nm has been synthesized utilizing reversible imine condensations between 5,10,15,20-tetrakis(4-aminophenyl)-porphyrin (TAPP) and a diketopyrrolopyrrole (DPP) dialdehyde derivative. Surprisingly, the obtained COF exhibited spontaneous aggregation into hollow microtubular assemblies with outer and inner tube diameters of around 300 and 90 nm...
October 26, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/29062097/altered-surface-mglur5-dynamics-provoke-synaptic-nmdar-dysfunction-and-cognitive-defects-in-fmr1-knockout-mice
#12
Elisabetta Aloisi, Katy Le Corf, Julien Dupuis, Pei Zhang, Melanie Ginger, Virginie Labrousse, Michela Spatuzza, Matthias Georg Haberl, Lara Costa, Ryuichi Shigemoto, Anke Tappe-Theodor, Filippo Drago, Pier Vincenzo Piazza, Christophe Mulle, Laurent Groc, Lucia Ciranna, Maria Vincenza Catania, Andreas Frick
Metabotropic glutamate receptor subtype 5 (mGluR5) is crucially implicated in the pathophysiology of Fragile X Syndrome (FXS); however, its dysfunction at the sub-cellular level, and related synaptic and cognitive phenotypes are unexplored. Here, we probed the consequences of mGluR5/Homer scaffold disruption for mGluR5 cell-surface mobility, synaptic N-methyl-D-aspartate receptor (NMDAR) function, and behavioral phenotypes in the second-generation Fmr1 knockout (KO) mouse. Using single-molecule tracking, we found that mGluR5 was significantly more mobile at synapses in hippocampal Fmr1 KO neurons, causing an increased synaptic surface co-clustering of mGluR5 and NMDAR...
October 24, 2017: Nature Communications
https://www.readbyqxmd.com/read/29052338/laparoscopic-transabdominal-preperitoneal-repair-for-strangulated-inguinal-hernia
#13
Akihisa Matsuda, Masao Miyashita, Satoshi Matsumoto, Nobuyuki Sakurazawa, Youichi Kawano, Sho Kuriyama, Kumiko Sekiguchi, Fumihiko Ando, Takeshi Matsutani, Eiji Uchida
INTRODUCTION: Laparoscopic transabdominal preperitoneal repair (TAPP) is widely accepted in elective inguinal hernioplasty. However, given the scarcity of data, the feasibility and safety of TAPP in strangulated hernia cases have not yet been determined. METHODS: We retrospectively evaluated the data from a consecutive series of 33 patients who had undergone surgery for acute strangulated inguinal hernia associated with suspected visceral ischemic damage by either TAPP (TAPP group, n = 11) or conventional open hernioplasty via the anterior approach (anterior group, n = 22)...
October 19, 2017: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/29030787/armillifer-infected-snakes-sold-at-congolese-bushmeat-markets-represent-an-emerging-zoonotic-threat
#14
Richard Hardi, Gergely Babocsay, Dennis Tappe, Mihály Sulyok, Imre Bodó, Lajos Rózsa
African pythons (Pythonidae) and large vipers (Bitis spp.) act as definitive hosts for Armillifer armillatus and Armillifer grandis parasites (Crustacea: Pentastomida) in the Congo Basin. Since the proportion of snakes in bushmeat gradually increases, human pentastomiasis is an emerging zoonotic disease. To substantiate the significance of this threat, we surveyed snakes offered for human consumption at bushmeat markets in the Kole district, Democratic Republic of the Congo, for the presence of adult pentastomids...
October 13, 2017: EcoHealth
https://www.readbyqxmd.com/read/28969193/comparing-early-outcomes-using-non-absorbable-polypropylene-mesh-and-partially-absorbable-composite-mesh-through-laparoscopic-transabdominal-preperitoneal-repair-of-inguinal-hernia
#15
Tarun Kalra, Rajesh Kumar Soni, Ajit Sinha
INTRODUCTION: Laparoscopic hernia repair is in vogue in the present era. Both the operating surgeon and the patient are concerned about the postoperative inguinodynia which has now replaced recurrence as the predominant factor affecting quality of life. AIM: Our study aimed to compare early postoperative outcomes with the standard non absorbablepolypropylene and the newer partially absorbable composite meshes. MATERIALS AND METHODS: A total of 60 patients with unilateral uncomplicated inguinal hernia were included in the study and randomly divided into two groups, one each for one kind of mesh...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28953552/lichtenstein-versus-total-extraperitoneal-patch-plasty-versus-transabdominal-patch-plasty-technique-for-primary-unilateral-inguinal-hernia-repair-a-registry-based-propensity-score-matched-comparison-of-57-906-patients
#16
Ferdinand Köckerling, Reinhard Bittner, Michael Kofler, Franz Mayer, Daniela Adolf, Andreas Kuthe, Dirk Weyhe
OBJECTIVE: Outcome comparison of the Lichtenstein, total extraperitoneal patch plasty (TEP), and transabdominal patch plasty (TAPP) techniques for primary unilateral inguinal hernia repair. BACKGROUND: For comparison of these techniques the number of cases included in meta-analyses of randomized controlled trials is limited. There is therefore an urgent need for more comparative data. METHODS: In total, 57,906 patients with a primary unilateral inguinal hernia and 1-year follow up from the Herniamed Registry were selected between September 1, 2009 and February 1, 2015...
September 26, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28927990/down-for-the-count-the-critical-endpoint-in-ototoxicity-remains-the-cytocochleogram
#17
REVIEW
David V Gauvin, Joshua Yoder, Andrea Koch, Zachary J Zimmermann, Rachel L Tapp
There are three major assays that must be conducted in standard investigational new drug (IND) -enabling ototoxicity study designs: 1) functional acoustic threshold measurements (Auditory Brainstem Respsonse, ABR); 2) otohistopathology and 3) cytocochleograms. We provide evidence to demonstrate the unreliability of auditory threshold shifts (ABRs) to predict cochlear cell death and build a case for conducting full cochlea processing and cell count measurements from the complete cochlea from apex to base.
September 18, 2017: Journal of Pharmacological and Toxicological Methods
https://www.readbyqxmd.com/read/28899789/the-evolutionary-logic-of-sepsis
#18
Lajos Rózsa, Péter Apari, Mihály Sulyok, Dennis Tappe, Imre Bodó, Richárd Hardi, Viktor Müller
The recently proposed Microbiome Mutiny Hypothesis posits that members of the human microbiome obtain information about the host individuals' health status and, when host survival is compromised, switch to an intensive exploitation strategy to maximize residual transmission. In animals and humans, sepsis is an acute systemic reaction to microbes invading the normally sterile body compartments. When induced by formerly mutualistic or neutral microbes, possibly in response to declining host health, sepsis appears to fit the 'microbiome mutiny' scenario except for its apparent failure to enhance transmission of the causative organisms...
September 9, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28892418/shared-decision-making-and-time-to-exacerbation-in-children-with-asthma
#19
Tsai-Ling Liu, Yhenneko J Taylor, Rohan Mahabaleshwarkar, Christopher M Blanchette, Hazel Tapp, Michael F Dulin
OBJECTIVE: Although shared decision making (SDM) is a promising approach for improving outcomes for patients with chronic diseases, no evidence currently supports the use of SDM to delay asthma exacerbations. We evaluated the impact of an SDM intervention implemented by providers in a real-world setting on time to exacerbation in children with asthma. METHODS: This study used a prospective cohort observed between 2011 and 2013 at five primary care practices that serve vulnerable populations (e...
September 11, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28888707/the-value-of-laparoscopy-in-the-management-of-chronic-groin-pain
#20
Abdulzahra Hussain, Ihsan Al-Shoek, Ajay Arora, Jonathan Walczak, Shamsi El-Hasani
BACKGROUND: Chronic groin pain problem represents a diagnostic and management challenge. This study is reporting all patients who underwent laparoscopic exploration of the groin and pelvis for undiagnosed chronic groin pain. MATERIALS AND METHODS: A retrospective cohort study. Evaluators were not involved in the operations. Laparoscopic exploration and mesh insertion using Trans-Abdominal Pre-Preitoneal (TAPP) approach was performed for all patients. Follow up in the; clinic at 2 weeks and 6 months was arranged...
October 2017: International Journal of Surgery
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