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https://www.readbyqxmd.com/read/28938737/complex-catsper-dependent-and-independent-ca2-i-signalling-in-human-spermatozoa-induced-by-follicular-fluid
#1
Sean G Brown, Sarah Costello, Mark C Kelly, Mythili Ramalingam, Ellen Drew, Stephen J Publicover, Christopher L R Barratt, Sarah Martins Da Silva
STUDY QUESTION: Does progesterone in human follicular fluid (hFF) activate CatSper and do other components of hFF modulate this effect and/or contribute separately to hFF-induced Ca2+ signaling? SUMMARY ANSWER: hFF potently stimulates CatSper and increases [Ca2+]i, primarily due to high concentrations of progesterone, however, other components of hFF also contribute to [Ca2+]i signaling, including modulation of CatSper channel activity and inhibition of [Ca2+]i oscillations...
October 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28937803/hip-arthroscopy-for-femoroacetabular-impingement-in-a-military-population
#2
Darren D Thomas, Andrew S Bernhardson, Ethan Bernstein, Christopher B Dewing
BACKGROUND: Femoroacetabular impingement (FAI) can lead to hip pain and early joint degeneration. There have been few reports to date on the outcomes of hip arthroscopy for the treatment of FAI in the military population. Purpose/Hypothesis: The purpose of this study was to compare patient demographics with postoperative outcomes after hip arthroscopy for symptomatic FAI and to identify preoperative risk factors for poor outcomes. The hypothesis was that certain preoperative patient characteristics will be predictive of poorer outcomes and that lower outcomes scores will be associated with a higher likelihood of medical separation from the military...
September 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28937772/terahertz-light-matter-interaction-beyond-unity-coupling-strength
#3
Andreas Bayer, Marcel Pozimski, Simon Schambeck, Dieter Schuh, Rupert Huber, Dominique Bougeard, Christoph Lange
Achieving control over light-matter interaction in custom-tailored nanostructures is at the core of modern quantum electrodynamics. In strongly and ultrastrongly coupled systems, the excitation is repeatedly exchanged between a resonator and an electronic transition at a rate known as the vacuum Rabi frequency ΩR. For ΩR approaching the resonance frequency ωc, novel quantum phenomena including squeezed states, Dicke superradiant phase transitions, the collapse of the Purcell effect, and a population of the ground state with virtual photon pairs are predicted...
September 22, 2017: Nano Letters
https://www.readbyqxmd.com/read/28937738/mussel-inspired-coating-and-adhesion-for-rechargeable-batteries-a-review
#4
You Kyeong Jeong, Sung Hyeon Park, Jang Wook Choi
A significant effort is currently being invested to improve the electrochemical performance of classical lithium-ion batteries (LIBs) or to accelerate the advent of new chemistry-based post-LIBs. Regardless of governing chemistry associated with charge storage, stable electrode-electrolyte interface and wet-adhesion among the electrode particles are universally desired for rechargeable batteries adopting liquid electrolytes. In this regard, recent studies have witnessed the usefulness of mussel-inspired polydopamine or catechol functional group in modifying the key battery components, such as active material, separator, and binder...
September 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28937376/meningioma-with-the-unique-coexistence-of-secretory-and-lipomatous-components-a-case-report-with-immunohistochemical-study
#5
Purwa R Patil, Bhushan M Warpe, Vijay H Juvekar, Vidya Manohar
Meningioma is the most common extra-axial neoplasm which accounts for 30% of all intracranial tumors with a female predilection. These tumors exhibit a broad spectrum of differentiation potency corresponding to different histological subtypes. Meningothelial cells can rarely show separate secretory or lipomatous (metaplastic) transformation. The coexistence of these two different histological subtypes in a single meningeal tumor is extremely rare with only two reported cases. We report an uncommon case of meningioma in a 40-year-old female showing histological admixture of both secretory and lipomatous (metaplastic) meningioma, which to our knowledge is only the third reported case in the world...
July 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28936842/-rapid-analysis-on-chemical-constituents-in-yinyanghuo-zonghuangtong-capsule-by-uplc-q-tof-ms-ms
#6
Xue-E Yu, Jian-Ping Qin, Jia-Chun Li, Wen-Zhe Huang, Zhen-Zhong Wang, Wei Xiao
To analyze and identify the chemical constituents from Yinyanghuo Zonghuangtong capsule by using UPLC/Q-TOF-MS/MS. Chromatographic separation was carried out on an Agilent SB-C₁₈ column (2.1 mm×100 mm, 1.8 μm) at the temperature of 30 ℃. The mobile phase was 0.1% formic acid and acetonitrile by gradient elution, with a flow rate at 0.30 mL•min⁻¹, and the injection volume of 2 μL. The MS spectrum was acquired in both negative and positive ion modes using ESI ion source. Based on relative accurate molecular weight, secondary mass spectrometry pyrolysis fragments and chromatographic peak retention time, as well as fragmentation regularity summarized from reference substance and the literature, we could effectively identify the chemical structure of the components under test...
December 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28936629/a-comparative-study-of-generic-visual-components-of-two-dimensional-versus-three-dimensional-laparoscopic-images
#7
Michael El Boghdady, Gobinath Ramakrishnan, Benjie Tang, Afshin Alijani
AIMS: There is a strong evidence to suggest that 3D imaging improves the laparoscopic task performance when compared against 2D. However, to date, no study has explained why that might be. We identified six generic visual components during laparoscopic imaging and aimed to study each component in both 2D and 3D environments for comparison. METHODS: Twenty-four consented laparoscopic novices performed specific isolated tasks in a laparoscopic Endo Trainer in 2D and 3D separately...
September 21, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28936624/dermal-epidermal-separation-methods-research-implications
#8
REVIEW
Ying Zou, Howard I Maibach
Dermal-epidermal separation is an important basic investigation technique for pharmacology, toxicology and biology. To choose the optimal method for a given research need, we reviewed studies on epidermal separation. PubMed, Embase, and Web of Science were utilized. Different separation systems have been compared, including chemical, enzyme, heat and mechanical separation; each has advantages and disadvantages. Heat is simple but causes thermal damage. Chemical reagents are effective but disturb cellular electrolyte equilibrium...
September 21, 2017: Archives of Dermatological Research
https://www.readbyqxmd.com/read/28936171/neural-activity-patterns-in-the-human-brain-reflect-tactile-stickiness-perception
#9
Junsuk Kim, Jiwon Yeon, Jaekyun Ryu, Jang-Yeon Park, Soon-Cheol Chung, Sung-Phil Kim
Our previous human fMRI study found brain activations correlated with tactile stickiness perception using the uni-variate general linear model (GLM) (Yeon et al., 2017). Here, we conducted an in-depth investigation on neural correlates of sticky sensations by employing a multivoxel pattern analysis (MVPA) on the same dataset. In particular, we statistically compared multi-variate neural activities in response to the three groups of sticky stimuli: A supra-threshold group including a set of sticky stimuli that evoked vivid sticky perception; an infra-threshold group including another set of sticky stimuli that barely evoked sticky perception; and a sham group including acrylic stimuli with no physically sticky property...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28936143/assessment-of-readiness-of-academic-emergency-departments-in-the-central-region-of-saudi-arabia-to-receive-a-sick-child
#10
Fahad Saleh Alhajjaj, Abdullah Saleh Aldamigh
OBJECTIVE: We sought to assess the readiness of general emergency departments (EDs) in academic hospitals in the central region of the Kingdom of Saudi Arabia (KSA) to manage pediatric patients using an international tool: The American Academy of Pediatrics, American College of Emergency Physicians, and Emergency Nurses Association guidelines, which include facilities, personnel, safety, and other components. METHODS: We assessed eligible centers during multiple visits from January 2016 to May 2016 in which we inspected the EDs and conducted interviews with their respective leadership in which we independently recorded our observations...
July 2017: International Journal of Health Sciences
https://www.readbyqxmd.com/read/28933430/a-binary-main-belt-comet
#11
Jessica Agarwal, David Jewitt, Max Mutchler, Harold Weaver, Stephen Larson
Asteroids are primitive Solar System bodies that evolve both collisionally and through disruptions arising from rapid rotation. These processes can lead to the formation of binary asteroids and to the release of dust, both directly and, in some cases, through uncovering frozen volatiles. In a subset of the asteroids called main-belt comets, the sublimation of excavated volatiles causes transient comet-like activity. Torques exerted by sublimation measurably influence the spin rates of active comets and might lead to the splitting of bilobate comet nuclei...
September 20, 2017: Nature
https://www.readbyqxmd.com/read/28932891/identification-of-terpenes-and-essential-oils-by-means-of-static-headspace-gas-chromatography-ion-mobility-spectrometry
#12
Roman Rodríguez-Maecker, Eduardo Vyhmeister, Stefan Meisen, Antonio Rosales Martinez, Andriy Kuklya, Ursula Telgheder
Static headspace gas chromatography-ion mobility spectrometry (SHS GC-IMS) is a relatively new analytical technique that has considerable potential for analysis of volatile organic compounds (VOCs). In this study, SHS GC-IMS was used for the identification of the major terpene components of various essential oils (EOs). Based on the data obtained from 25 terpene standards and 50 EOs, a database for fingerprint identification of characteristic terpenes and EOs was generated utilizing SHS GC-IMS for authenticity testing of fragrances in foods, cosmetics, and personal care products...
September 20, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28931458/redox-active-reactions-in-denitrification-provided-by-biochars-pyrolyzed-at-different-temperatures
#13
Guanhong Chen, Zhirong Zhang, Zhiyuan Zhang, Renduo Zhang
The aim of this study was to investigate the role of redox-active components of biochar in the denitrification processes and N2O reduction. Both biochars pyrolyzed at 300 and 800°C were separated into two redox-active components (i.e., dissolved aromatic moieties and condensed aromatic structure), then applied to study the reduction process of denitrifying bacteria from a paddy soil. Results demonstrated three main pathways of the biochar redox-active components for the denitrification processes and N2O reduction...
September 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28931294/-carney-triad
#14
L Fiala, I Kocáková, R Šimůnek, E Krejčí, I Babánková, R Šefr
Carney triad is a synchronous or metachronous association of gastric gastrointestinal stromal tumors (GIST), pulmonary chondroma and extra-adrenal paraganglioma. The majority of patients have only one or two components of the triad, all three tumors being found in only about 2% of the patients at the time of the first diagnosis. The most common combination is gastric and pulmonary tumors. We report a case of Carney triad which was diagnosed at Masaryk Memorial Cancer Institute. A 57-year-old female patient with a history of gastric resection for leiomyosarcoma at the age of 14 and with an unclear pulmonary lesion evident on chest X-ray since as early as 2003...
2017: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/28931181/-refractive-lens-exchange
#15
Fritz H Hengerer, Ina Conrad-Hengerer
In refractive surgery the removal of the natural lens followed by implantation of an artificial intraocular lens has been an established method to treat refractive errors. The term "clear lens exchange" separates this approach from cataract surgery, where a cloudy lens has to be removed. With regard to currently available intraocular lens technologies, there is a wide range to correct myopia, hyperopia as well as astigmatism. Trifocal or extended depth-of-focus lenses (EDOF) even with a toric component offer the patients a potential benefit to further address presbyopia, respectively...
September 20, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28931012/cbta-toxin-of-escherichia-coli-inhibits-cell-division-and-cell-elongation-via-direct-and-independent-interactions-with-ftsz-and-mreb
#16
Danielle M Heller, Mrinalini Tavag, Ann Hochschild
The toxin components of toxin-antitoxin modules, found in bacterial plasmids, phages, and chromosomes, typically target a single macromolecule to interfere with an essential cellular process. An apparent exception is the chromosomally encoded toxin component of the E. coli CbtA/CbeA toxin-antitoxin module, which can inhibit both cell division and cell elongation. A small protein of only 124 amino acids, CbtA, was previously proposed to interact with both FtsZ, a tubulin homolog that is essential for cell division, and MreB, an actin homolog that is essential for cell elongation...
September 20, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28930217/influence-of-different-isolation-methods-on-chemical-composition-and-bioactivities-of-the-fruit-peel-oil-of-citrus-medica-l-var-sarcodactylis-noot-swingle
#17
Gang Deng, Jonathan D Craft, Kelly Marie Steinberg, Pei Lei Li, Suraj Kumar Pokharel, William N Setzer
Background: The chemical composition and bioactivities of essential oils (EOs) of fingered citron (Citrus medica L. var. sarcodactylis (Noot.) Swingle) are considerably sensitive and lapsible during high-temperature processing of traditional separating techniques. In the present research, vacuum distillation and ultrafiltration were utilized in order to process the concentrated juice from fingered citron, obtaining a high-quality essential oil. Methods: In order to compare the essential oils obtained by conventional means, the chemical compositions of the essential oils were analyzed using GC-MS, before antimicrobial and antioxidant screening assays were carried out...
January 4, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28929685/-simultaneous-determination-of-8-main-compounds-in-eclipta-herba-by-uplc
#18
Xue-Feng Hou, Shuai Sun, Gang Wang, Hui-Hui Qiu, Shu-Min Ding, Ying Liu, Dan Liu, Liang Feng, Xiao-Bin Jia
To establish an UPLC method for the simultaneous determination of 8 compounds in Eclipta Herba, such as isoquercitrin, luteoloside, demethylwedelolactone, isochlorogenic acid A, isochlorogenic acid C, luteolin, wedelolactone and apigenin. The experiment was performed with a Waters Acquity UPLC BEH C₁₈ (2.1 mm×100 mm, 1.7 μm) column by gradient elution of 0.1% formic acid in water and acetonitrile: 0-4 min,10%-13% A; 4-10 min, 13%-16% A; 10-13 min, 16%-25% A; 13-17 min, 25%-28% A; 17-20 min,28%-40% A;20-25 min,40%-95% A...
November 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28929013/constructing-three-emotion-knowledge-tests-from-the-invariant-measurement-approach
#19
Ana R Delgado, Gerardo Prieto, Debora I Burin
BACKGROUND: Psychological constructionist models like the Conceptual Act Theory (CAT) postulate that complex states such as emotions are composed of basic psychological ingredients that are more clearly respected by the brain than basic emotions. The objective of this study was the construction and initial validation of Emotion Knowledge measures from the CAT frame by means of an invariant measurement approach, the Rasch Model (RM). Psychological distance theory was used to inform item generation...
2017: PeerJ
https://www.readbyqxmd.com/read/28928647/individual-differences-in-frequency-and-topography-of-slow-and-fast-sleep-spindles
#20
Roy Cox, Anna C Schapiro, Dara S Manoach, Robert Stickgold
Sleep spindles are transient oscillatory waveforms that occur during non-rapid eye movement (NREM) sleep across widespread cortical areas. In humans, spindles can be classified as either slow or fast, but large individual differences in spindle frequency as well as methodological difficulties have hindered progress towards understanding their function. Using two nights of high-density electroencephalography recordings from 28 healthy individuals, we first characterize the individual variability of NREM spectra and demonstrate the difficulty of determining subject-specific spindle frequencies...
2017: Frontiers in Human Neuroscience
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