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Trigger point therapy

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https://www.readbyqxmd.com/read/29231319/-efficacy-on-primary-trigeminal-neuralgia-treated-with-triple-puncture-technique-and-electroacupuncture-at-trigger-points
#1
Zhuang Huang, Jin Huo, Jiongqi Zhao
OBJECTIVE: To compare the clinical efficacy on primary trigeminal neuralgia between the combined therapy of electroacupuncture and triple puncture and the routine electroacupuncture therapy. METHODS: Thirty-six patients of primary trigeminal neuralgia were randomly assigned into an electroacupuncture and triple puncture group (group A) and a routine electroacupuncture group (group B), 18 cases in each one. In the group A, the triple puncture technique was used at the trigger points (the positive reactive points to trigger facial pain) and stimulated with electricity...
January 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29227293/an-ex-vivo-model-of-shear-rate-based-activation-of-blood-coagulation
#2
Marco Ranucci, Matteo Ranucci, Ekaterina Baryshnikova
: The study presents a model of shear-stress-based platelet activation. Twenty-eight patients (22 free from anticoagulants and major antiplatelet agents, and six under the effects of P2Y12 platelet inhibitors) participated. The main purpose was to verify the hypothesis that a model of shear-dependent blood activation does not require artificial activators to trigger clot formation. Whole blood collected from the patients received platelet function tests [ADPtest and thrombin receptor-activating peptide (TRAP)test] and was tested with a cone-on-plate viscosimeter at a shear rate of 100 s...
December 8, 2017: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/29216730/the-influence-of-cranio-cervical-rehabilitation-in-patients-with-myofascial-temporomandibular-pain-disorders
#3
K Halmova, D Holly, P Stanko
OBJECTIVE: The aim of the study was to prove the causality between the craniocervical dysfunction and myofascial pain in the head and neck and to demonstrate the clinical value and usefulness of physiotherapy as one of the therapeutic options for myofascial pain. METHODS: The group of patients diagnosed with myofascial dysfunctional pain syndrome contained 98 patients out of which 79 patients (81 %) were females and 19 patients (19 %) were males. The majority of the patients were aged between 26 and 35 years; the total age range was 14-77 years with the average of 38 years...
2017: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/29206666/immediate-effects-of-simultaneous-application-of-transcutaneous-electrical-nerve-stimulation-and-ultrasound-phonophoresis-on-active-myofascial-trigger-points-a-randomized-controlled-trial
#4
Mary Kamal Nassif Takla, Soheir Shethata Rezk-Allah Rezk
OBJECTIVE: was to investigate the efficacy of phonophoresis with combined therapy (PH-CT) on active myofascial trigger points (MTrPs). PARTICIPANTS: One hundred participants with acute mechanical neck pain and at least one active MTrP in the upper trapezius were randomly assigned into 4 equal groups. INTERVENTION: Groups consisted of; diclofenac PH-CT; diclofenac phonophoresis (PH); ultrasound (US) with coupling gel and sham-US; applied for 10 minutes over MTrP...
December 5, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29199529/-in-the-sport-i-am-here-therapeutic-processes-and-health-effects-of-sport-and-exercise-on-ptsd
#5
Clemens Ley, María Rato Barrio, Andreas Koch
Current evidence suggests positive effects of exercise on posttraumatic stress symptoms; however, knowledge about how these effects are achieved is limited. Thus, this study aims to contribute to a more holistic understanding of these effects. We performed a single case study of a war and torture survivor, who was diagnosed with posttraumatic stress disorder (PTSD) and depression, and who was participant of the sport and exercise therapy program Movi Kune. Participant observation was conducted as well as semi-structured interviews with the participant and his psychotherapist...
December 1, 2017: Qualitative Health Research
https://www.readbyqxmd.com/read/29199503/smart-arm-training-with-outcome-triggered-electrical-stimulation-in-subacute-stroke-survivors-with-severe-arm-disability-a-randomized-controlled-trial
#6
Ruth N Barker, Kathryn S Hayward, Richard G Carson, David Lloyd, Sandra G Brauer
BACKGROUND: Stroke survivors with severe upper limb disability need opportunities to engage in task-oriented practice to achieve meaningful recovery. OBJECTIVE: To compare the effect of SMART Arm training, with or without outcome-triggered electrical stimulation to usual therapy, on arm function for stroke survivors with severe upper limb disability undergoing inpatient rehabilitation. METHODS: A prospective, multicenter, randomized controlled trial was conducted with 3 parallel groups, concealed allocation, assessor blinding and intention-to-treat analysis...
December 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29194781/toward-customized-extracellular-niche-engineering-progress-in-cell-entrapment-technologies
#7
REVIEW
Dilip Thomas, Timothy O'Brien, Abhay Pandit
The primary aim in tissue engineering is to repair, replace, and regenerate dysfunctional tissues to restore homeostasis. Cell delivery for repair and regeneration is gaining impetus with our understanding of constructing tissue-like environments. However, the perpetual challenge is to identify innovative materials or re-engineer natural materials to model cell-specific tissue-like 3D modules, which can seamlessly integrate and restore functions of the target organ. To devise an optimal functional microenvironment, it is essential to define how simple is complex enough to trigger tissue regeneration or restore cellular function...
December 1, 2017: Advanced Materials
https://www.readbyqxmd.com/read/29140756/cellular-and-molecular-mechanisms-of-autoimmune-hepatitis
#8
G J Webb, G M Hirschfield, E L Krawitt, M E Gershwin
Autoimmune hepatitis is an uncommon idiopathic syndrome of immunemediated destruction of hepatocytes, typically associated with autoantibodies. The disease etiology is incompletely understood but includes a clear association with human leukocyte antigen (HLA) variants and other non- HLA gene variants, female sex, and the environment. Pathologically, there is a CD4+ T cell-rich lymphocytic inflammatory infiltrate with variable hepatocyte necrosis and subsequent hepatic fibrosis. Attempts to understand pathogenesis are informed by several monogenetic syndromes that may include autoimmune liver injury, by several drug and environmental agents that have been identified as triggers in a minority of cases, by human studies that point toward a central role for CD4+ effector and regulatory T cells, and by animal models of the disease...
November 15, 2017: Annual Review of Pathology
https://www.readbyqxmd.com/read/29105476/-clinical-observation-of-the-proprioceptive-sensibility-reflexotherapy-by-tendon-acupuncture-at-trigger-points-for-cervical-vertigo
#9
Fen-Fen Yao, Jun Luo, Jiao Liu, Wen-Yao Fang, Chen-Yu Zhang, Sheng Zhang, Yu-Lin Mao, Zhen Yuan, Kai Wang
OBJECTIVE: To evaluate the efficacy of the proprioceptive sensibility reflexotherapy by tendon acupuncture needling at trigger points for patients with proprioceptive disorder of cervical vertigo. METHODS: Seventy-nine patients with proprioceptive disorder of cervical vertigo were randomly assigned into a treatment group (42 cases) and a control group (37 cases). Patients in the treatment group received the proprioceptive sensibility reflexotherapy with tendon acupuncture at trigger points in the neck...
October 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29101238/glucocorticoid-resistance-is-reverted-by-lck-inhibition-in-pediatric-t-cell-acute-lymphoblastic-leukemia
#10
Valentina Serafin, Giorgia Capuzzo, Gloria Milani, Sonia Anna Minuzzo, Marica Pinazza, Roberta Bortolozzi, Silvia Bresolin, Elena Porcù, Chiara Frasson, Stefano Indraccolo, Giuseppe Basso, Benedetta Accordi
Pediatric T-acute lymphoblastic leukemia (T-ALL) patients often display resistance to glucocorticoid (GC) treatment. These patients, classified as Prednisone Poor Responders (PPR), have poorer outcome compared to the other pediatric T-ALL patients receiving a high-risk adapted therapy. Since glucocorticoids are administered to ALL patients during all the different phases of therapy, GC resistance represents an important challenge to be addressed in order to improve the outcome for these patients. Mechanisms underlying resistance are not yet fully unraveled, thus our research focused on the identification of deregulated signaling pathways to point out new targeted approaches...
November 3, 2017: Blood
https://www.readbyqxmd.com/read/29091134/increased-peripheral-blood-tcd4-counts-and-serum-sp-d-levels-in-patients-with-chronic-paracoccidioidomycosis-during-and-after-antifungal-therapy
#11
James Venturini, Ricardo Souza Cavalcante, Tatiane Fernanda Sylvestre, Rodolfo Ferreira Dos Santos, Daniela Vanessa Moris, Lídia Raquel Carvalho, Maria Sueli Parreira de Arruda, Marjorie de Assis Golim, Rinaldo Poncio Mendes
BACKGROUND: The main clinical forms of paracoccidioidomycosis (PCM) are the acute/subacute form (AF) and the chronic form (CF), and they both display considerable clinical variability. The immune responses of PCM patients, during and after treatment, remain neglected, mainly in the case of CF patients, due to the high prevalence of pulmonary sequelae. OBJECTIVE: To evaluate the distribution of whole blood T cell subsets, serum cytokines, and biomarkers of pulmonary fibrosis in PCM patients, according to the clinical form and at different time points, during the antifungal therapy...
November 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/29081381/inflammageing-and-metaflammation-the-yin-and-yang-of-type-2-diabetes
#12
REVIEW
Francesco Prattichizzo, Valeria De Nigris, Rosangela Spiga, Elettra Mancuso, Lucia La Sala, Roberto Antonicelli, Roberto Testa, Antonio Domenico Procopio, Fabiola Olivieri, Antonio Ceriello
Type 2 diabetes mellitus (T2DM) is characterised by chronic low-grade inflammation, recently referred to as 'metaflammation', a relevant factor contributing to the development of both diabetes and its complications. Nonetheless, 'canonical' anti-inflammatory drugs do not yield satisfactory results in terms of prevention of diabetes progression and of cardiovascular events, suggesting that the causal mechanisms fostering metaflammation deserve further research to identify new druggable targets. Metaflammation resembles ageing-induced low-grade inflammation, previously referred to as inflammageing, in terms of clinical presentation and the molecular profile, pointing to a common aetiology for both conditions...
October 31, 2017: Ageing Research Reviews
https://www.readbyqxmd.com/read/29078865/effectiveness-safety-and-predictors-of-response-to-botulinum-toxin-type-a-in-refractory-masticatory-myalgia-a-retrospective-study
#13
Shehryar N Khawaja, Steven J Scrivani, Nicole Holland, David A Keith
PURPOSE: Masticatory muscle pain disorders respond well to conservative therapy; however, in some patients the pain becomes refractory. Botulinum toxin type A (BoT-A) therapy has been shown to be an effective modality in the management of refractory headache disorders. Conversely, there are conflicting reports in the literature regarding the efficacy, safety, and predictors of therapeutic response to BoT-A therapy for management of refractory masticatory muscle pain. MATERIALS AND METHODS: We performed a retrospective chart review of patients who underwent at least 2 injection cycles of 100 U of BoT-A for refractory masticatory myalgia in the Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, between May 2012 and June 2016...
November 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29046485/dimethyl-fumarate-increases-fetal-hemoglobin-provides-heme-detoxification-and-corrects-anemia-in-sickle-cell-disease
#14
Sriram Krishnamoorthy, Betty Pace, Dipti Gupta, Sarah Sturtevant, Biaoru Li, Levi Makala, Julia Brittain, Nancy Moore, Benjamin F Vieira, Timothy Thullen, Ivan Stone, Huo Li, William E Hobbs, David R Light
Sickle cell disease (SCD) results from a point mutation in the β-globin gene forming hemoglobin S (HbS), which polymerizes in deoxygenated erythrocytes, triggering recurrent painful vaso-occlusive crises and chronic hemolytic anemia. Reactivation of fetal Hb (HbF) expression ameliorates these symptoms of SCD. Nuclear factor (erythroid derived-2)-like 2 (Nrf2) is a transcription factor that triggers cytoprotective and antioxidant pathways to limit oxidative damage and inflammation and increases HbF synthesis in CD34+ stem cell-derived erythroid progenitors...
October 19, 2017: JCI Insight
https://www.readbyqxmd.com/read/29037652/the-local-twitch-response-during-trigger-point-dry-needling-is-it-necessary-for-successful-outcomes
#15
Thomas Perreault, James Dunning, Raymond Butts
BACKGROUND: Myofascial trigger point (MTrP) injection and trigger point dry needling (TrPDN) are widely accepted therapies for myofascial pain syndrome (MPS). Empirical evidence suggests eliciting a local twitch response (LTR) during needling is essential. OBJECTIVE: This is the first review exploring the available literature, regardless of study design, on the neurophysiological effects and clinical significance of the LTR as it relates to reductions in pain and disability secondary to MTrP needling...
October 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29037648/test-retest-reliability-of-myofascial-trigger-point-detection-in-hip-and-thigh-areas
#16
E Rozenfeld, A S Finestone, U Moran, E Damri, L Kalichman
BACKGROUND: Myofascial trigger points (MTrP's) are a primary source of pain in patients with musculoskeletal disorders. Nevertheless, they are frequently underdiagnosed. Reliable MTrP palpation is the necessary for their diagnosis and treatment. The few studies that have looked for intra-tester reliability of MTrPs detection in upper body, provide preliminary evidence that MTrP palpation is reliable. Reliability tests for MTrP palpation on the lower limb have not yet been performed. OBJECTIVE: To evaluate inter- and intra-tester reliability of MTrP recognition in hip and thigh muscles...
October 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29026893/descending-necrotizing-mediastinitis-after-a-trigger-point-injection
#17
Jae Young Choe, Jong Kun Kim, Dong Eun Lee, Kang Suk Seo, Jung Bae Park, Mi Jin Lee, Hyun Wook Ryoo, Jae Yun Ahn, Sungbae Moon
Descending necrotizing mediastinitis (DNM) is a rare form of mediastinal infection. Most cases are associated with esophageal rupture. DNM after a trigger point injection in the upper trapezius has not been described previously. We present a case of DNM after a trigger point injection in the upper trapezius. A 70-year-old man visited the emergency department with chest discomfort and fever after a trigger point injection in the left upper trapezius. Chest computed tomography showed evidence of DNM, and antibiotic therapy was immediately administered intravenously...
September 2017: Clinical and Experimental Emergency Medicine
https://www.readbyqxmd.com/read/29026068/hollow-mno2-as-a-tumor-microenvironment-responsive-biodegradable-nano-platform-for-combination-therapy-favoring-antitumor-immune-responses
#18
Guangbao Yang, Ligeng Xu, Yu Chao, Jun Xu, Xiaoqi Sun, Yifan Wu, Rui Peng, Zhuang Liu
Herein, an intelligent biodegradable hollow manganese dioxide (H-MnO2) nano-platform is developed for not only tumor microenvironment (TME)-specific imaging and on-demand drug release, but also modulation of hypoxic TME to enhance cancer therapy, resulting in comprehensive effects favoring anti-tumor immune responses. With hollow structures, H-MnO2 nanoshells post modification with polyethylene glycol (PEG) could be co-loaded with a photodynamic agent chlorine e6 (Ce6), and a chemotherapy drug doxorubicin (DOX)...
October 12, 2017: Nature Communications
https://www.readbyqxmd.com/read/28990015/efficacy-of-the-twin-block-a-peripheral-nerve-block-for-the-management-of-chronic-masticatory-myofascial-pain-a-case-series
#19
Veena Kanti, Sowmya Ananthan, Gayathri Subramanian, Samuel Y P Quek
Masticatory myofascial pain is the one of the most common etiologies for nonodontogenic pain, often characterized by the presence of trigger points. Conventional management includes approaches such as jaw exercises, physical therapy, intraoral appliances, medications, and trigger point injections. Peripheral/regional nerve blocks have shown to be effective in managing myogenous pain conditions. The twin block is a nerve block that blocks both the masseteric and the anterior deep temporal nerves. The objective of this case series is to illustrate expeditious and sustained efficacy of the twin block in the management of chronic masticatory myofascial pain...
October 6, 2017: Quintessence International
https://www.readbyqxmd.com/read/28985333/nonhuman-primate-models-of-neurodegenerative-disorders
#20
Marina E Emborg
Alzheimer's (AD), Huntington's (HD), and Parkinson's (PD) disease are age-related neurodegenerative disorders characterized by progressive neuronal cell death. Although each disease has particular pathologies and symptoms, accumulated evidence points to similar mechanisms of neurodegeneration, including inflammation, oxidative stress, and protein aggregation. A significant body of research is ongoing to understand how these pathways affect each other and what ultimately triggers the onset of the disease. Experiments in nonhuman primates (NHPs) account for only 5% of all research in animals...
August 10, 2017: ILAR Journal
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