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https://www.readbyqxmd.com/read/28188757/cognitive-effects-of-androgen-deprivation-therapy-in-men-with-advanced-prostate-cancer
#1
Bulent Gunlusoy, Yasin Ceylan, Aslı Koskderlioglu, Muhtesem Gedizlioglu, Tansu Degirmenci, Pınar Ortan, Zafer Kozacioglu
OBJECTIVES: To evaluate prostate cancer effects of androgen deprivation therapy (ADT) by using a systematic set of methods to calculate specific cognitive functions in men with locally advanced or metastatic prostate cancer. METHODS: From April 2014 to February 2016, a prospective, comparative study was done to evaluate the cognitive effects of hormone therapy.Group 1 consisted of 78 patients with locally advanced or metastatic prostate cancer who received complete ADT treatment continously for 12 months and group 2 (control group) consisted of 78 patients who underwent radical prostatectomy without any additional treatment...
February 7, 2017: Urology
https://www.readbyqxmd.com/read/28169819/-study-of-two-indicators-of-difficulty-in-initiating-maternal-breastfeeding-160-maternal-fatigue-and-suboptimal-infant-breastfeeding-behaviour
#2
Latifa Saidi, Pierre Godbout
<ce:para>The problems with setting up breastfeading are common and are associated with a heightened risk of weening. The main motives brought up by the mothers for early weening were fatigue and the suboptimal infant breastfeeding behaviour (SIBB). The goal of this study is to describe the fatigue levels of breastfeading women who gave birth to healthy full term babies in a hospital setting and the SIBB. This study also examines the relation between these two variables.</ce:para><ce:para>This descriptive correlational and cross-sectional study was conducted with breasfeeding women who gave birth to healthy, full term, single babies at the CHU in Moncton between June and September 2013...
July 5, 2016: Recherche en Soins Infirmiers
https://www.readbyqxmd.com/read/28133531/in-vitro-assesment-of-anti-inflammatory-activities-of-coumarin-and-indonesian-cassia-extract-in-raw264-7-murine-macrophage-cell-line
#3
Ni Made Dwi Sandhiutami, Moordiani Moordiani, Dian Ratih Laksmitawati, Nurul Fauziah, Maesaroh Maesaroh, Wahyu Widowati
OBJECTIVES: Inflammation is an immune response toward injuries. Although inflammation is healing response, but in some condition it will lead to chronic disease such as rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, Alzheimer's and various cancer. Indonesian cassia (Cinnamomum burmannil C. Nees & T. Ness) known to contain coumarin, is widely used for alternative medicine especially as an anti-inflammatory. This study was conducted to determine the anti-inflammatory properties of coumarin and Indonesian cassia extract (ICE) in LPS-induced RAW264...
January 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28124624/accessing-gap-junction-channel-structure-function-relationships-through-molecular-modeling-and-simulations
#4
REVIEW
F Villanelo, Y Escalona, C Pareja-Barrueto, J A Garate, I M Skerrett, T Perez-Acle
BACKGROUND: Gap junction channels (GJCs) are massive protein channels connecting the cytoplasm of adjacent cells. These channels allow intercellular transfer of molecules up to ~1 kDa, including water, ions and other metabolites. Unveiling structure-function relationships coded into the molecular architecture of these channels is necessary to gain insight on their vast biological function including electrical synapse, inflammation, development and tissular homeostasis. From early works, computational methods have been critical to analyze and interpret experimental observations...
January 17, 2017: BMC Cell Biology
https://www.readbyqxmd.com/read/28123331/prevalence-of-hypercalciuria-and-urinary-calcium-excretion-in-school-aged-children-in-the-province-of-tokat
#5
Ali Gül, Samet Özer, Resul Yılmaz, Ergün Sönmezgöz, Tuba Kasap, Şahin Takçı, Erhan Karaaslan, Yalçın Önder, Rıza Çıtıl, İlknur Bütün, Osman Demir
AIM: Hypercalciuria is an important cause of urinary tract symptoms, and also frequently results in urolithiasis. Urinary calcium excretion varies for geographic areas. We aimed to assess percentiles of urinary calcium excretion and prevalence of hypercalciuria for school-aged children in Tokat (city located in inner northern region of Turkey). MATERIAL AND METHODS: One thousand three hundred seventy-five children aged 6 to 18 years were enrolled in the study. Urine samples were obtained randomly...
December 2016: Türk Pediatri Arşivi
https://www.readbyqxmd.com/read/28118778/a-systematic-review-of-the-research-evidence-for-the-benefits-of-teledentistry
#6
Mohamed Estai, Yogesan Kanagasingam, Marc Tennant, Stuart Bunt
Objective This review is designed to inform future decisions about the benefits of integrating teledentistry into routine health services, by presenting an overview of the evidence for the effectiveness and economic impact of teledentistry. Methods Two reviewers searched PubMed, EMBASE and CINAHL databases through November 2016 to identify published peer-reviewed studies in English. Teledentistry studies were included if they were; (a) controlled (randomised or non-randomised) assessment studies; and (b) compared outcomes of a teledentistry intervention in terms of clinical or economic evaluation with the outcomes of traditional clinical alternatives...
January 1, 2017: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/28113508/subpixel-image-quality-assesement-syncretizing-local-subpixel-and-global-pixel-features
#7
Jin Zeng, Lu Fang, Jiahao Pang, Houqiang Li, Feng Wu
Subpixel rendering technology increases the apparent resolution of an LCD/OLED screen by exploiting the physical property that a pixel is composed of RGB individually addressable subpixels. Due to the intrinsic intercoordination between apparent luminance resolution and color fringing artifact, a common method of subpixel image assessment is subjective evaluation. In this paper, we propose a unified subpixel image quality assessment metric called SubPixel image Assessment (SPA), which syncretizes local subpixel and global pixel features...
October 5, 2016: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28108855/causes-of-poor-outcome-in-patients-admitted-with-good-grade-subarachnoid-haemorrhage
#8
Vladimír Beneš, Lubomír Jurák, Radim Brabec, Nina Nechanická, Miroslav Šercl, Ladislav Endrych, Pavel Buchvald, Petr Suchomel
BACKGROUND: Surgical risk in patients with unruptured aneurysms is well known. The relative impact of surgery and natural history of subarachnoid haemorrhage (SAH) on patients in good clinical condition (World Federation of Neurological Surgeons [WFNS] grades 1 and 2) is less well quantified. The aim of this study was to determine causes of poor outcome in patients admitted in good grade SAH. METHODS: A retrospective study of prospectively collected data among WFNS-1 and -2 patients: demographics, SAH and aneurysm-related data, surgical complications and outcome as assesed by the Glasgow Outcome Scale (GOS)...
March 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28107710/in-vivo-assesment-of-the-genotoxic-and-oxidative-stress-effects-of-particulate-matter-on-echinogammarus-veneris
#9
Melissa Marcoccia, Lucilla Ronci, Elvira De Matthaeis, Andrea Setini, Cinzia Perrino, Silvia Canepari
Seven types of atmospheric dusts (road dust, soil dust, brake dust, desert dust, pellet ash and coke and certified material NIST1648a - urban dust) have been tested for their genotoxicity on specimens of Echinogammarus veneris, a small aquatic amphipod. Experiments were carried out in vivo, by exposing the animals for 24 h to water containing 25 mg/L of dust. Each dust has been chemically analyzed for ions, elemental carbon, organic carbon and for the soluble and insoluble fractions of elements. Non-specific damages to DNA have been evaluated by the comet test, while oxidative damages have been estimated by coupling the comet test with formamido pyrimidine DNA glycosylase reaction...
January 6, 2017: Chemosphere
https://www.readbyqxmd.com/read/28072692/role-of-biochemistry-and-cytological-analysis-of-cyst-fluid-for-the-differential-diagnosis-of-pancreatic-cysts-a-retrospective-cohort-study
#10
Ozlem Mutluay Soyer, Bulent Baran, Asli Ciftcibasi Ormeci, Davut Sahin, Suut Gokturk, Sami Evirgen, Rafet Basar, Pinar Firat, Filiz Akyuz, Kadir Demir, Fatih Besisik, Sabahattin Kaymakoglu, Cetin Karaca
BACKGROUND: Management of pancreatic cysts is based on neoplastic-nonneoplastic discrimination. Endoscopic ultrasound (EUS) enables to differentiate neoplastic-nonneoplastic lesions and also allows fine-needle aspiration (FNA). In this study, we aim to assess feasibility and clinical relevance of cytological and biochemical analysis in differential diagnosis of cystic pancreatic lesions in patients who had undergone endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) due to pancreatic cysts...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28070464/the-acceptability-of-tv-based-game-platforms-as-an-instrument-to-support-the-cognitive-evaluation-of-senior-adults-at-home
#11
Carlos Rivas Costa, Manuel José Fernández Iglesias, Luis Eulogio Anido Rifón, Miguel Gómez Carballa, Sonia Valladares Rodríguez
INTRODUCTION: The computing capabilities of state-of-the-art television sets and media centres may facilitate the introduction of computer-assisted evaluation at home. This approach would help to overcome the drawbacks of traditional pen-and-paper evaluations administered in clinical facilities, as they could be performed in a more comfortable environment, the subject's home, and they would be more flexible for designing complex environments for the evaluation of neuropsychological constructs that are difficult to assess through traditional testing...
2017: PeerJ
https://www.readbyqxmd.com/read/28044992/assesment-quality-of-life-for-chronic-myeloid-leukemia-patients-by-using-eortcqol-c30
#12
Mehmet Can Uğur, Yaşar Bekir Kutbay, Özge Özer Kaya, Cengiz Ceylan
No abstract text is available yet for this article.
December 30, 2016: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28039474/preclinical-assesement-of-survivin-and-xiap-as-prognostic-biomarkers-and-therapeutic-targets-in-gastroenteropancreatic-neuroendocrine-neoplasia
#13
Levent Dizdar, Kira A Oesterwind, Jasmin C Riemer, Thomas A Werner, Sabrina Mersch, Birte Möhlendick, Sina C Schütte, Pablo E Verde, Katharina Raba, Stefan A Topp, Nikolas H Stoecklein, Irene Esposito, Wolfram T Knoefel, Andreas Krieg
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) represent a rare and heterogenous tumor entity. Importantly, the highly proliferative subgroup of neuroendocrine carcinoma (GEP-NEC) is characterized by high resistance to conventional chemotherapy. Consequently, there is an urgent need to identify novel therapeutic targets, especially for GEP-NEC. Thus, we focused on Inhibitor of apoptosis protein (IAP) family members survivin and XIAP that orchestrate inhibition of apoptosis, induce resistance against chemotherapeutics and facilitate tumor metastasis...
January 31, 2017: Oncotarget
https://www.readbyqxmd.com/read/28024228/vector-field-statistics-for-the-analysis-of-time-varying-clinical-gait-data
#14
C J Donnelly, C Alexander, T C Pataky, K Stannage, S Reid, M A Robinson
BACKGROUND: In clinical settings, the time varying analysis of gait data relies heavily on the experience of the individual(s) assessing these biological signals. Though three dimensional kinematics are recognised as time varying waveforms (1D), exploratory statistical analysis of these data are commonly carried out with multiple discrete or 0D dependent variables. In the absence of an a priori 0D hypothesis, clinicians are at risk of making type I and II errors in their analyis of time varying gait signatures in the event statistics are used in concert with prefered subjective clinical assesment methods...
December 3, 2016: Clinical Biomechanics
https://www.readbyqxmd.com/read/27992361/risk-factors-that-affect-metabolic-health-status-in-obese-children
#15
Selin Elmaogullari, Fatma Demirel, Nihal Hatipoglu
BACKGROUND: While some obese children are metabolically healthy (MHO), some have additional health problems, such as hypertension, dyslipidemia, insulin resistance, and hepatosteatosis, which increase mortality and morbidity related to cardiovascular diseases (CVD) during adulthood. These children are metabolically unhealthy obese (MUO) children. In this study we assessed the factors that affect metabolic health in obesity and the clinical and laboratory findings that distinguish between MHO and MUO children...
January 1, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/27970975/the-evolution-and-comparison-of-hta-assesment-organisations-in-selected-european-countries
#16
A Beletsi, V Koutrafouri, E Karampli, E Pavi
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27970946/assesing-the-average-price-level-of-generics-in-greece-and-other-comparable-european-countries-relative-to-their-volume-market-share
#17
C Papadopoulos, D Lolos, M Ollandezos
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27970450/nine-tests-for-assesing-validity-of-a-discrete-choice-experiment
#18
E M Janssen, J F Bridges
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27941201/-peripheral-nerves-alcoholization-in-the-spasticity-managament
#19
Karolina Turżańska, Sławomir Zaborek, Agnieszka Posturzyńska, Joanna Niezbecka, Aneta Zarębska, Mirosław Jabłoński
INTRODUCTION: Spasticity is velocity dependent increased resistance to passive lengthening of the muscle. Mild spasticity doesn't require treatment, but severe impede with hygiene, constrict range of motion and mobility, interfere with gait pattern and can be the cause of pain and discomfort. Proper spasticity management is crucial for correct rehabilitation. THE AIM OF THE STUDY: The assesment of chemodenervation with ethyl alcohol in spasticity treatment. MATERIAL AND METHODS: 13 patients (5 female, 8 male) age 18-68 yrs (mean 46,8±13,3)...
2016: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/27895371/rotational-mal-alignment-after-reamed-intramedullary-nailing-for-tibial-shaft-fracture
#20
Sher Baz Khan, Yasir Mohib, Rizwan Haroon Rashid, Haroonur Rashid
Intra-medullary (IM) nailing is standard of care for unstable tibial shaft fractures. Malrotation is very common but it is under-recognised, inpart because of variation in normal anatomy and partly due to difficulty in accurately assessing rotation. This study was planned to evaluate the frequency of rotational mal-alignment after reamed tibia IMnailing. This cross-sectional study was conducted at Aga khan University Hospital, Karachi, and comprised patients with tibia shaft fractures managed with IMnailing from January to December 2014...
October 2016: JPMA. the Journal of the Pakistan Medical Association
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