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Stroke neurorehabilitation

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https://www.readbyqxmd.com/read/28226940/design-and-optimization-of-partner-a-parallel-actuated-robotic-trainer-for-neurorehabilitation
#1
Hossein Taheri, Stephen A Goodwin, James A Tigue, Joel C Perry, Eric T Wolbrecht, Hossein Taheri, Stephen A Goodwin, James A Tigue, Joel C Perry, Eric T Wolbrecht, James A Tigue, Joel C Perry, Hossein Taheri, Stephen A Goodwin, Eric T Wolbrecht
Robotic devices are a promising and dynamic tool in the realm of post-stroke rehabilitation. Researchers are still investigating how the use of robots affects motor learning and what design characteristics best encourage recovery. We present a parallel-actuated, end-effector robot designed to provide spatial assistance for upper-limb therapy while exhibiting low impedance and high backdrivability. A gradient based optimization was performed to find an optimal design that accounted for force isotropy, mechanical advantage, workspace size, and counter-balancing...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28222551/the-top-100-cited-neurorehabilitation-papers
#2
Jeffrey S Kreutzer, Amma A Agyemang, David Weedon, Nathan Zasler, Melissa Oliver, Aaron A Sorensen, Saskia van Wijngaarden, Eileen Leahy
BACKGROUND: Neurorehabilitation covers a large range of disorders, treatment approaches and methods. There have been previous citation analyses of rehabilitation and of its subfields. However, there has never been a comprehensive citation analysis in neurorehabilitation. OBJECTIVE: The present study reports findings from a citation analysis of the top 100 most cited neurorehabilitation papers to describe the research trends in the field. METHODS: A de-novo keyword search of papers indexed in the Web of Science Core Collection database yielded 52,581 papers...
January 7, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28194413/patient-centered-robot-aided-passive-neurorehabilitation-exercise-based-on-safety-motion-decision-making-mechanism
#3
Lizheng Pan, Aiguo Song, Suolin Duan, Zhuqing Yu
Safety is one of the crucial issues for robot-aided neurorehabilitation exercise. When it comes to the passive rehabilitation training for stroke patients, the existing control strategies are usually just based on position control to carry out the training, and the patient is out of the controller. However, to some extent, the patient should be taken as a "cooperator" of the training activity, and the movement speed and range of the training movement should be dynamically regulated according to the internal or external state of the subject, just as what the therapist does in clinical therapy...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28191352/hybrid-assistive-neuromuscular-dynamic-stimulation-therapy-a-new-strategy-for-improving-upper-extremity-function-in-patients-with-hemiparesis-following-stroke
#4
REVIEW
Toshiyuki Fujiwara, Michiyuki Kawakami, Kaoru Honaga, Michi Tochikura, Kaoru Abe
Hybrid Assistive Neuromuscular Dynamic Stimulation (HANDS) therapy is one of the neurorehabilitation therapeutic approaches that facilitates the use of the paretic upper extremity (UE) in daily life by combining closed-loop electromyography- (EMG-) controlled neuromuscular electrical stimulation (NMES) with a wrist-hand splint. This closed-loop EMG-controlled NMES can change its stimulation intensity in direct proportion to the changes in voluntary generated EMG amplitudes recorded with surface electrodes placed on the target muscle...
2017: Neural Plasticity
https://www.readbyqxmd.com/read/28190440/neurologic-complications-in-critically-ill-pregnant-patients
#5
W L Wright
Neurologic complications in a critically ill pregnant woman are uncommon but some of the complications (such as eclampsia) are unique to pregnancy and the puerperal period. Other neurologic complications (such as seizures in the setting of epilepsy) may worsen during pregnancy. Clinical signs and symptoms such as seizure, headache, weakness, focal neurologic deficits, and decreased level of consciousness require careful consideration of potential causes to ensure prompt treatment measures are instituted to prevent ongoing neurologic injury...
2017: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/28091936/task-specific-motor-rehabilitation-therapy-after-stroke-improves-performance-in-a-different-motor-task-translational-evidence
#6
M El Amki, P Baumgartner, O Bracko, A R Luft, S Wegener
While the stroke survivor with a motor deficit strives for recovery of all aspects of daily life movements, neurorehabilitation training is often task specific and does not generalize to movements other than the ones trained. In rodent models of post-stroke recovery, this problem is poorly investigated as the training task is often the same as the one that measures motor function. The present study investigated whether motor training by pellet reaching translates into enhancement of different motor functions in rats after stroke...
January 14, 2017: Translational Stroke Research
https://www.readbyqxmd.com/read/28050939/book-review-stroke-interventions-to-support-occupational-performance-neurorehabilitation-in-occupational-therapy-series-wolf-timothy-j-ed-2014-stroke-interventions-to-support-occupational-performance-neurorehabilitation-in-occupational-therapy-series-vol-2
#7
https://www.readbyqxmd.com/read/28009677/effectiveness-of-temporary-deafferentation-of-the-arm-on-somatosensory-and-motor-functions-following-stroke-a-systematic-review
#8
Emmanuelle Opsommer, Camille Zwissig, Natalya Korogod, Thomas Weiss
BACKGROUND: After stroke, regaining functional use of the upper limb can be challenging. Temporary deafferentation (TD) is a novel approach used in neurorehabilitation to voluntarily reduce the somatosensory input in a body part by temporary anesthesia; which has been shown to improve sensorimotor functions in the affected limb. OBJECTIVES: The primary objective of this systematic review was to present the best available evidence related to the effects of TD of the affected arm on the recovery of motor function and activity of the upper limb (arm and hand) following stroke...
December 2016: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28004991/bilateral-versus-ipsilesional-cortico-subcortical-activity-patterns-in-stroke-show-hemispheric-dependence
#9
A Cristina Vidal, Paula Banca, Augusto G Pascoal, Gustavo C Santo, João Sargento-Freitas, Ana Gouveia, Miguel Castelo-Branco
Background Understanding of interhemispheric interactions in stroke patients during motor control is an important clinical neuroscience quest that may provide important clues for neurorehabilitation. In stroke patients, bilateral overactivation in both hemispheres has been interpreted as a poor prognostic indicator of functional recovery. In contrast, ipsilesional patterns have been linked with better motor outcomes. Aim We investigated the pathophysiology of hemispheric interactions during limb movement without and with contralateral restraint, to mimic the effects of constraint-induced movement therapy...
January 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/27993584/functional-independence-a-comparison-of-the-changes-during-neurorehabilitation-between-patients-with-nontraumatic-subarachnoid-hemorrhage-and-patients-with-intracerebral-hemorrhage-or-acute-ischemic-stroke
#10
Henriette Holm Stabel, Asger Roer Pedersen, Søren Paaske Johnsen, Jørgen Feldbæk Nielsen
OBJECTIVE: To compare the changes in functional independence measured by the FIM after specialized neurorehabilitation between patients with nontraumatic subarachnoid hemorrhage (SAH) and patients with intracerebral hemorrhage (ICH) or acute ischemic stroke (AIS). DESIGN: Historical cohort study comparing changes in functional independence between patients with nontraumatic SAH and those with ICH/AIS, using FIM scores from a local database and clinical information from the Danish National Patient Registry...
December 16, 2016: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/27988346/experiencing-a-reaching-task-passively-with-one-arm-while-adapting-to-a-visuomotor-rotation-with-the-other-can-lead-to-substantial-transfer-of-motor-learning-across-the-arms
#11
Shancheng Bao, Yuming Lei, Jinsung Wang
The extent of transfer following visuomotor adaptation across the arms is typically limited as compared to that within the same arm. However, we have demonstrated that interlimb transfer can occur nearly completely if one arm performs reaching movements associated with a desired trajectory repeatedly and actively during an initial training session in which the other arm adapts to a novel visuomotor adaptation. Based on that finding, we argued that the absence of instances associated with specific motor effectors is the major reason for limited interlimb transfer...
December 14, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/27926448/increasing-self-directed-training-in-neurorehabilitation-patients-through-competition
#12
B Studer, H Van Dijk, R Handermann, S Knecht
This proof-of-concept study aimed to test whether competition could be a useful tool to increase intensity and amount of self-directed training in neurorehabilitation. Stroke patients undergoing inpatient neurorehabilitation (n=93) conducted self-directed endurance training on a (wheelchair-compatible) bicycle trainer under three experimental conditions: a "Competition" condition and two noncompetition control conditions (repeated randomized within-subject design). Training performance and perceived exertion were recorded and statistically analyzed...
2016: Progress in Brain Research
https://www.readbyqxmd.com/read/27884966/setting-up-a-neuroscience-stroke-and-rehabilitation-centre-in-brunei-darussalam-by-a-transcontinental-on-site-and-telemedical-cooperation
#13
U Meyding-Lamadé, B Bassa, E Craemer, C Jacobi, C Chan, W Hacke, B Kress
Due to the world-wide aging population, there is a need for specialist neurological knowledge, treatment and care. Stroke treatment is effective in reducing mortality and disability, but it is still not available in many areas of the world. We describe the set-up process of a specialized Neuroscience, Stroke and Rehabilitation Centre in Brunei Darussalam (BNSRC) in cooperation with a German hospital. This study details the setup of a stroke-, neurological intensive care- and neurorehabilitation unit, laboratories and a telemedical network to perform all evidence-based stroke treatments...
November 24, 2016: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/27871449/botulinum-toxin-as-early-intervention-for-spasticity-after-stroke-or-non-progressive-brain-lesion-a-meta-analysis
#14
Raymond L Rosales, Fran Efendy, Ericka Sa Teleg, Mary Md Delos Santos, Mary Ce Rosales, Marc Ostrea, Michelle J Tanglao, Arlene R Ng
Spasticity is a functionally limiting disorder that commonly occurs following stroke or severe brain injury, and may lead to disability and pain. In tandem with neurorehabilitation, botulinum toxin type A (BoNT-A) is the recommended first-line treatment for spasticity and, to date, the majority of trials have reported BoNT-A use in patients >6months after ictus. The present meta-analysis aimed to evaluate the effects of early BoNT-A injection for post-stroke spasticity on improvements in hypertonicity, disability, function and associated pain...
December 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27861901/chloride-co-transporters-as-possible-therapeutic-targets-for-stroke
#15
REVIEW
Miguel A S Martín-Aragón Baudel, Amy V Poole, Mark G Darlison
Stroke is one of the major causes of death and disability worldwide. The major type of stroke is an ischaemic one, which is caused by a blockage that interrupts blood flow to the brain. There are currently very few pharmacological strategies to reduce the damage and social burden triggered by this pathology. The harm caused by the interruption of blood flow to the brain unfolds in the subsequent hours and days, so it is critical to identify new therapeutic targets that could reduce neuronal death associated with the spread of the damage...
November 15, 2016: Journal of Neurochemistry
https://www.readbyqxmd.com/read/27858095/-new-aspects-of-neurorehabilitation-motor-and-language
#16
J Liepert, C Breitenstein
Advancements in medical care over the last decades have contributed to a continuous decline in immediate post-stroke mortality. The flipside of this development is that patients surviving the initial stroke are forced to live with sometimes extreme functional motor and/or language limitations for the remaining life span. The following overview presents evidence-based neurorehabilitative interventions to promote motor and language recovery in the acute and chronic post-stroke stages. Therapeutic approaches comprise intensive training, neuropharmacological drugs and non-invasive brain stimulation techniques, such as transcranial magnetic stimulation (TMS) or direct current stimulation (tDCS)...
December 2016: Der Nervenarzt
https://www.readbyqxmd.com/read/27846623/paracrine-mechanisms-of-intravenous-bone-marrow-derived-mononuclear-stem-cells-in-chronic-ischemic-stroke
#17
Ashu Bhasin, M V Padma Srivastava, Sujata Mohanty, Sivasubramaniam Vivekanandhan, Sakshi Sharma, Senthil Kumaran, Rohit Bhatia
BACKGROUND: The emerging role of stem cell technology and transplantation has helped scientists to study their potential role in neural repair and regeneration. The fate of stem cells is determined by their niche, consisting of surrounding cells and the secreted trophic growth factors. This interim report evaluates the safety, feasibility and efficacy (if any) of bone marrow-derived mononuclear stem cells (BM-MNC) in chronic ischemic stroke by studying the release of serum vascular endothelial growth factor (VEGF) and brain-derived neurotrophic growth factor (BDNF)...
October 19, 2016: Cerebrovascular Diseases Extra
https://www.readbyqxmd.com/read/27826223/self-paced-reaching-after-stroke-a-quantitative-assessment-of-longitudinal-and-directional-sensitivity-using-the-h-man-planar-robot-for-upper-limb-neurorehabilitation
#18
Asif Hussain, Aamani Budhota, Charmayne Mary Lee Hughes, Wayne D Dailey, Deshmukh A Vishwanath, Christopher W K Kuah, Lester H L Yam, Yong J Loh, Liming Xiang, Karen S G Chua, Etienne Burdet, Domenico Campolo
Technology aided measures offer a sensitive, accurate and time-efficient approach for the assessment of sensorimotor function after neurological insult compared to standard clinical assessments. This study investigated the sensitivity of robotic measures to capture differences in planar reaching movements as a function of neurological status (stroke, healthy), direction (front, ipsilateral, contralateral), movement segment (outbound, inbound), and time (baseline, post-training, 2-week follow-up) using a planar, two-degrees of freedom, robotic-manipulator (H-Man)...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27818001/simultaneous-eeg-fnirs-reveals-how-age-and-feedback-affect-motor-imagery-signatures
#19
Catharina Zich, Stefan Debener, Ann-Kathrin Thoene, Ling-Chia Chen, Cornelia Kranczioch
Stroke frequently results in motor impairment. Motor imagery (MI), the mental practice of movements, has been suggested as a promising complement to other therapeutic approaches facilitating motor rehabilitation. Of particular potential is the combination of MI with neurofeedback (NF). However, MI NF protocols have been largely optimized only in younger healthy adults, although strokes occur more frequently in older adults. The present study examined the influence of age on the neural correlates of MI supported by electroencephalogram (EEG)-based NF and on the neural correlates of motor execution...
January 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/27790612/muscle-synergies-facilitate-computational-prediction-of-subject-specific-walking-motions
#20
Andrew J Meyer, Ilan Eskinazi, Jennifer N Jackson, Anil V Rao, Carolynn Patten, Benjamin J Fregly
Researchers have explored a variety of neurorehabilitation approaches to restore normal walking function following a stroke. However, there is currently no objective means for prescribing and implementing treatments that are likely to maximize recovery of walking function for any particular patient. As a first step toward optimizing neurorehabilitation effectiveness, this study develops and evaluates a patient-specific synergy-controlled neuromusculoskeletal simulation framework that can predict walking motions for an individual post-stroke...
2016: Frontiers in Bioengineering and Biotechnology
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