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Stroke neurorehabilitation

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https://www.readbyqxmd.com/read/28550098/contralesional-brain-computer-interface-control-of-a-powered-exoskeleton-for-motor-recovery-in-chronic-stroke-survivors
#1
David T Bundy, Lauren Souders, Kelly Baranyai, Laura Leonard, Gerwin Schalk, Robert Coker, Daniel W Moran, Thy Huskey, Eric C Leuthardt
BACKGROUND AND PURPOSE: There are few effective therapies to achieve functional recovery from motor-related disabilities affecting the upper limb after stroke. This feasibility study tested whether a powered exoskeleton driven by a brain-computer interface (BCI), using neural activity from the unaffected cortical hemisphere, could affect motor recovery in chronic hemiparetic stroke survivors. This novel system was designed and configured for a home-based setting to test the feasibility of BCI-driven neurorehabilitation in outpatient environments...
May 26, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28518079/a-method-for-quantifying-upper-limb-performance-in-daily-life-using-accelerometers
#2
Catherine E Lang, Kimberly J Waddell, Joseph W Klaesner, Marghuretta D Bland
A key reason for referral to rehabilitation services after stroke and other neurological conditions is to improve one's ability to function in daily life. It has become important to measure a person's activities in daily life, and not just measure their capacity for activity in the structured environment of a clinic or laboratory. A wearable sensor that is now enabling measurement of daily movement is the accelerometer. Accelerometers are commercially-available devices resembling large wrist watches that can be worn throughout the day...
April 21, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28512066/use-of-electroencephalography-brain-computer-interface-systems-as-a-rehabilitative-approach-for-upper-limb-function-after-a-stroke-a-systematic-review
#3
REVIEW
Esther Monge-Pereira, Jaime Ibañez-Pereda, Isabel M Alguacil-Diego, Jose I Serrano, María P Spottorno-Rubio, Francisco Molina-Rueda
BACKGROUND: Brain computer interface (BCI) systems have been suggested as a promising tool for neurorehabilitation. However, to date, there is a lack of homogeneous findings. Furthermore, no systematic reviews have analyzed the degree of validation of these interventions for upper limb (UL) motor rehabilitation post-stroke. OBJECTIVES: To compile all available studies that assess an UL intervention based on an electroencephalography (EEG) - BCI system in stroke...
May 13, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28506003/synergy-effects-of-combined-multichannel-emg-triggered-electrical-stimulation-and-mirror-therapy-in-subacute-stroke-patients-with-severe-or-very-severe-arm-hand-paresis
#4
Thomas Schick, Hans-Peter Schlake, Juliane Kallusky, Günter Hohlfeld, Maria Steinmetz, Florian Tripp, Karsten Krakow, Michaela Pinter, Christian Dohle
BACKGROUND: Neurorehabilitation requires the development of severity-dependent and successful therapies for arm/hand rehabilitation in stroke patients. OBJECTIVE: To evaluate the effectiveness of adding mirror therapy to bilateral EMG-triggered multi-channel electrostimulation for the treatment of severe arm/hand paresis in stroke patients. METHODS: The subjects of this randomized, controlled, multicentre study were stroke patients who had suffered their first insult between 1 and 6 months before study start and had severe or very severe arm/hand paresis, as classified by Fugl-Meyer-Assessment...
May 9, 2017: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/28505985/upper-limb-robotics-applied-to%C3%A2-neurorehabilitation-an-overview-of%C3%A2-clinical-practice
#5
Christophe Duret, Stefano Mazzoleni
BACKGROUND: During the last two decades, extensive interaction between clinicians and engineers has led to the development of systems that stimulate neural plasticity to optimize motor recovery after neurological lesions. This has resulted in the expansion of the field of robotics for rehabilitation. Studies in patients with stroke-related upper-limb paresis have shown that robotic rehabilitation can improve motor capacity. However, few other applications have been evaluated (e.g. tremor, peripheral nerve injuries or other neurological diseases)...
May 10, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28412953/quantification-of-task-dependent-cortical-activation-evoked-by-robotic-continuous-wrist-joint-manipulation-in-chronic-hemiparetic-stroke
#6
Martijn P Vlaar, Teodoro Solis-Escalante, Julius P A Dewald, Erwin E H van Wegen, Alfred C Schouten, Gert Kwakkel, Frans C T van der Helm
BACKGROUND: Cortical damage after stroke can drastically impair sensory and motor function of the upper limb, affecting the execution of activities of daily living and quality of life. Motor impairment after stroke has been thoroughly studied, however sensory impairment and its relation to movement control has received less attention. Integrity of the somatosensory system is essential for feedback control of human movement, and compromised integrity due to stroke has been linked to sensory impairment...
April 17, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28374692/-the-features-of-botulinum-therapy-for-different-patterns-of-poststroke-spasticity
#7
L V Krylova, D R Khasanova
AIM: To assess the efficacy of botulinum toxin therapy for different patterns of poststroke spasticity. MATERIAL AND METHODS: Thirty-nine patients with poststroke spasticity were examined. Rehabilitation included 4 treatment courses of inpatient rehabilitation during 9 month usinga multidisciplinary team approach. Botulinum toxin therapy was included in the program. The individual program was developed taking into account the dynamics of a pathological spastic pattern...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28367834/electroencephalographic-identifiers-of-motor-adaptation-learning
#8
Ozan Ozdenizci, Mustafa Yalcin, Ahmetcan Erdogan, Volkan Patoglu, Moritz Grosse-Wentrup, Mujdat Cetin
OBJECTIVE: Recent brain-computer interface (BCI) assisted stroke rehabilitation protocols tend to focus on sensorimotor activity of the brain. Relying on evidence claiming that a variety of brain rhythms beyond sensorimotor areas are related to the extent of motor deficits, we propose to identify neural correlates of motor learning beyond sensorimotor areas spatially and spectrally for further use in novel BCI-assisted neurorehabilitation settings. APPROACH: Electroencephalographic (EEG) data were recorded from healthy subjects participating in a physical force-field adaptation task involving reaching movements through a robotic handle...
April 3, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28360842/neuroplastic-changes-following-brain-ischemia-and-their-contribution-to-stroke-recovery-novel-approaches-in-neurorehabilitation
#9
REVIEW
Claudia Alia, Cristina Spalletti, Stefano Lai, Alessandro Panarese, Giuseppe Lamola, Federica Bertolucci, Fabio Vallone, Angelo Di Garbo, Carmelo Chisari, Silvestro Micera, Matteo Caleo
Ischemic damage to the brain triggers substantial reorganization of spared areas and pathways, which is associated with limited, spontaneous restoration of function. A better understanding of this plastic remodeling is crucial to develop more effective strategies for stroke rehabilitation. In this review article, we discuss advances in the comprehension of post-stroke network reorganization in patients and animal models. We first focus on rodent studies that have shed light on the mechanisms underlying neuronal remodeling in the perilesional area and contralesional hemisphere after motor cortex infarcts...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28356180/nocturnal-desaturation-is-associated-with-atrial-fibrillation-in-patients-with-ischemic-stroke-and-obstructive-sleep-apnea
#10
Chung-Yao Chen, Chien-Hui Ho, Chia-Ling Chen, Chung-Chieh Yu
STUDY OBJECTIVES: Both atrial fibrillation (AF) and obstructive sleep apnea (OSA) are risk factors for ischemic stroke. Previous studies suggested that OSA is associated with AF in individuals who have not had a stroke. For better secondary prevention of stroke, this study determined the association between OSA and AF among patients with ischemic stroke. METHODS: This cross-sectional study recruited consecutive patients with subacute ischemic stroke admitted for neurorehabilitation...
May 15, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28351495/ethical-considerations-in-providing-an-upper-limb-exoskeleton-device-for-stroke-patients
#11
Adriana E Bulboacă, Sorana D Bolboacă, Angelo C Bulboacă
The health care system needs to face new and advanced medical technologies that can improve the patients' quality of life by replacing lost or decreased functions. In stroke patients, the disabilities that follow cerebral lesions may impair the mandatory daily activities of an independent life. These activities are dependent mostly on the patient's upper limb function so that they can carry out most of the common activities associated with a normal life. Therefore, an upper limb exoskeleton device for stroke patients can contribute a real improvement of quality of their life...
April 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28351388/buyang-huanwu-decoction-facilitates-neurorehabilitation-through-an-improvement-of-synaptic-plasticity-in-cerebral-ischemic-rats
#12
Ruihuan Pan, Jun Cai, Lechang Zhan, Youhua Guo, Run-Yue Huang, Xiong Li, Mingchao Zhou, Dandan Xu, Jie Zhan, Hongxia Chen
BACKGROUND: Loss of neural function is a critical but unsolved issue after cerebral ischemia insult. Neuronal plasticity and remodeling are crucial for recovery of neural functions after brain injury. Buyang Huanwu decoction, which is a classic formula in traditional Chinese medicine, can positively alter synaptic plasticity. This study assessed the effects of Buyang Huanwu decoction in combination with physical exercise on neuronal plasticity in cerebral ischemic rats. METHODS: Cerebral ischemic rats were administered Buyang Huanwu decoction and participated in physical exercise after the induction of a permanent middle cerebral artery occlusion...
March 28, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28345282/neuroplasticity-of-language-in-left-hemisphere-stroke-evidence-linking-subsecond-electrophysiology-and-structural-connections
#13
Vitória Piai, Lars Meyer, Nina F Dronkers, Robert T Knight
The understanding of neuroplasticity following stroke is predominantly based on neuroimaging measures that cannot address the subsecond neurodynamics of impaired language processing. We combined behavioral and electrophysiological measures and structural-connectivity estimates to characterize neuroplasticity underlying successful compensation of language abilities after left-hemispheric stroke. We recorded the electroencephalogram from patients with stroke lesions to the left temporal lobe and from matched controls during context-driven word retrieval...
June 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28302915/sex-differences-in-ischaemic-stroke-potential-cellular-mechanisms
#14
REVIEW
Anjali Chauhan, Hope Moser, Louise D McCullough
Stroke remains a leading cause of mortality and disability worldwide. More women than men have strokes each year, in part because women live longer. Women have poorer functional outcomes, are more likely to need nursing home care and have higher rates of recurrent stroke compared with men. Despite continued advancements in primary prevention, innovative acute therapies and ongoing developments in neurorehabilitation, stroke incidence and mortality continue to increase due to the aging of the U.S. POPULATION: Sex chromosomes (XX compared with XY), sex hormones (oestrogen and androgen), epigenetic regulation and environmental factors all contribute to sex differences...
April 1, 2017: Clinical Science (1979-)
https://www.readbyqxmd.com/read/28293701/diffusion-tensor-imaging-as-a-prognostic-biomarker-for-motor-recovery-and-rehabilitation-after-stroke
#15
REVIEW
Josep Puig, Gerard Blasco, Gottfried Schlaug, Cathy M Stinear, Pepus Daunis-I-Estadella, Carles Biarnes, Jaume Figueras, Joaquín Serena, Maria Hernández-Pérez, Angel Alberich-Bayarri, Mar Castellanos, David S Liebeskind, Andrew M Demchuk, Bijoy K Menon, Götz Thomalla, Kambiz Nael, Max Wintermark, Salvador Pedraza
PURPOSE: Despite improved acute treatment and new tools to facilitate recovery, most patients have motor deficits after stroke, often causing disability. However, motor impairment varies considerably among patients, and recovery in the acute/subacute phase is difficult to predict using clinical measures alone, particularly in severely impaired patients. Accurate early prediction of recovery would help rationalize rehabilitation goals and improve the design of trials testing strategies to facilitate recovery...
March 14, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28286474/parameters-and-measures-in-assessment-of-motor-learning-in-neurorehabilitation-a-systematic-review-of-the-literature
#16
REVIEW
Nataliya Shishov, Itshak Melzer, Simona Bar-Haim
Upper limb function, essential for daily life, is often impaired in individuals after stroke and cerebral palsy (CP). For an improved upper limb function, learning should occur, and therefore training with motor learning principles is included in many rehabilitation interventions. Despite accurate measurement being an important aspect for examination and optimization of treatment outcomes, there are no standard algorithms for outcome measures selection. Moreover, the ability of the chosen measures to identify learning is not well established...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28280482/using-biophysical-models-to-understand-the-effect-of-tdcs-on-neurorehabilitation-searching-for-optimal-covariates-to-enhance-poststroke-recovery
#17
Paola Malerba, Sofia Straudi, Felipe Fregni, Maxim Bazhenov, Nino Basaglia
Stroke is a leading cause of worldwide disability, and up to 75% of survivors suffer from some degree of arm paresis. Recently, rehabilitation of stroke patients has focused on recovering motor skills by taking advantage of use-dependent neuroplasticity, where high-repetition of goal-oriented movement is at times combined with non-invasive brain stimulation, such as transcranial direct current stimulation (tDCS). Merging the two approaches is thought to provide outlasting clinical gains, by enhancing synaptic plasticity and motor relearning in the motor cortex primary area...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28272726/-measurement-of-the-outcomes-in-acquired-brain-injury-in-a-neurorehabilitation-unit-a-long-term-study
#18
V Cruz-Guisado, P Diaz-Borrego, B Romero-Romero, M Rodriguez-Pinero Duran
INTRODUCTION: Following sudden brain damage, there is a loss of capabilities that affects the person's autonomy. Recovery from the physical, psychic and cognitive sequelae requires the application of multiple therapies, the outcomes of which need to be measured objectively. Our aim is to analyse the application of standardised instruments in determining the therapeutic outcomes in acquired brain injury. PATIENTS AND METHODS: We conducted a retrospective descriptive observational study lasting 13 months...
March 16, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28270632/-rehabilitation-using-repetitive-transcranial-magnetic-stimulation
#19
Naoyuki Takeuchi, Shin-Ichi Izumi
Various novel stroke rehabilitative methods have been developed based on findings in basic science and clinical research. Recently, many reports have shown that repetitive transcranial magnetic stimulation (rTMS) improves function in stroke patients by altering the excitability of the human cortex. The interhemispheric competition model proposes that deficits in stroke patients are due to reduced output from the affected hemisphere and excessive interhemispheric inhibition from the unaffected hemisphere to the affected hemisphere...
March 2017: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/28268752/design-and-optimization-of-partner-a-parallel-actuated-robotic-trainer-for-neurorehabilitation
#20
Hossein Taheri, Stephen A Goodwin, James A Tigue, Joel C Perry, Eric T Wolbrecht
Robotic devices are a promising and dynamic tool in the realm of post-stroke rehabilitation. Researchers are still investigating how the use of robots affects motor learning and what design characteristics best encourage recovery. We present a parallel-actuated, end-effector robot designed to provide spatial assistance for upper-limb therapy while exhibiting low impedance and high backdrivability. A gradient based optimization was performed to find an optimal design that accounted for force isotropy, mechanical advantage, workspace size, and counter-balancing...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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