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ankle brachial index

Moritz S Bischoff, K Meisenbacher, A S Peters, D Weber, T Bisdas, G Torsello, D Böckler
PURPOSE: To evaluate the significance of perioperative changes in ankle-brachial index (ABI) with regard to extremity-related outcome in non-diabetic patients with critical limb ischemia (CLI) following revascularization. METHODS: The study represents a subanalysis of the multicentric Registry of First-line Treatment in Patients with CLI (CRITISCH). After exclusion of diabetic patients, conservative cases, and primary major amputation, 563 of 1200 CRITISCH patients (mean age 74 ± 10...
June 17, 2018: Langenbeck's Archives of Surgery
Zhuo Gao, Xiaomei Li, Jing Miao, Lide Lun
BACKGROUND: Secondary hyperparathyroidism (SHPT) and calcium and phosphorus metabolism disorder are important complications in haemodialysis patients. Parathyroidectomy (PTX) may prevent or delay the progress of vascular calcification in haemodialysis patients. OBJECTIVE: To investigate the impacts of PTX on calcium and phosphorus metabolism, arterial calcification and arterial stiffness in haemodialysis patients with SHPT. METHODS: Twenty-one SHPT-haemodialysis patients were selected for PTX...
June 13, 2018: Asian Journal of Surgery
Hua Ling, Ebony Andrews, David Ombengi, Fang Li
Background: Patients with peripheral arterial disease (PAD) undergoing percutaneous coronary intervention (PCI) are at elevated risk of ischemic and bleeding events. However, the optimal duration of dual antiplatelet therapy (DAPT) after PCI in patients with PAD remains unclear. Methods: A systematic literature search was performed through June 2017 using PubMed, EMBASE and Cochrane databases with the following key terms: "dual antiplatelet therapy", "P2Y12 inhibitor", "myocardial infarction", "percutaneous coronary intervention", "stent", "peripheral arterial disease", and "ankle-brachial index"...
June 2018: Cardiology Research
Toshiaki Ohkuma, Toshiharu Ninomiya, Hirofumi Tomiyama, Kazuomi Kario, Satoshi Hoshide, Yoshikuni Kita, Toyoshi Inoguchi, Yasutaka Maeda, Katsuhiko Kohara, Yasuharu Tabara, Motoyuki Nakamura, Takayoshi Ohkubo, Hirotaka Watada, Masanori Munakata, Mitsuru Ohishi, Norihisa Ito, Michinari Nakamura, Tetsuo Shoji, Charalambos Vlachopoulos, Victor Aboyans, Akira Yamashina
BACKGROUND AND AIMS: The ankle-brachial index (ABI) is a predictor of cardiovascular disease (CVD) and premature death. However, few studies on this marker are available in the general Asian populations. This study aimed to investigate the association between ABI measured with oscillometry and the risk of these outcomes. METHODS: We conducted an individual participant data meta-analysis in 10,679 community-dwelling Japanese individuals without a history of CVD. The primary outcome was a composite of CVD events and all-cause mortality...
May 31, 2018: Atherosclerosis
Weishuai Lian, Xiaoxiao Hu, Long Pan, Shilong Han, Chuanwu Cao, Zhongzhi Jia, Maoquan Li
BACKGROUND: The goal of this study was to characterize the properties of human CD34+ cells in culture and investigate the feasibility and efficacy of CD34+ transplantation in a mouse model of limb ischemia and in patients with no-option critical limb ischemia. METHODS: Human CD34+ cells isolated from peripheral blood and grown in culture for up to four passages stained positively for the surface markers CD34 and CD133 and showed high viability after cryopreservation and recovery...
June 11, 2018: Journal of Clinical Laboratory Analysis
Patrick Björkman, Tommi Auvinen, Harri Hakovirta, Pekka Romsi, Johanna Turtiainen, Hannu Manninen, Maarit Venermo, Kimmo Lappalainen, Anders Albäck, Antti Korpela, Kimmo Mäkinen, Petri Saari, Jukka Perälä
INTRODUCTION: Claudication and critical limb threatening ischemia (CLTI) are significant causes of mortality in the elderly. The gold standard of superficial femoral artery (SFA) revascularization is thus far considered to be the femoropopliteal bypass. The aim of this study was to compare mid-term patency between drug-eluting stents (DES) and prosthetic bypass grafts (BSX). Studies have reported comparable results for both methods. MATERIALS AND METHODS: 46 patients with claudication or rest pain due to a 5-25 cm SFA-occlusion were randomized between DES and BSX...
June 7, 2018: Annals of Vascular Surgery
Thomas F X O'Donnell, Sarah E Deery, Marc L Schermerhorn, Jeffrey J Siracuse, Daniel J Bertges, Alik Farber, Robert T Lancaster, Virendra I Patel
OBJECTIVE: Ankle-brachial index (ABI) is a common method of graft surveillance after infrainguinal bypass surgery (LEB), and is recommended by the Society for Vascular Surgery (SVS). Several studies failed to show benefit of ABI surveillance, but were limited by sample size, and the practice remains variable. METHODS: We identified all patients who underwent LEB for occlusive disease from the Vascular Study Group of New England Registry (VSGNE) between 2003-2016...
June 6, 2018: Annals of Vascular Surgery
Antoaneta Gateva, Yavor Assyov, Tsvetan Gatev, Zdravko Kamenov
AIM: The aim of the present study was to investigate the prevalence of macrovascular complications across different carbohydrate disturbances. PATIENTS AND METHODS: In the study, we included 167 patients, divided them into three age and BMI matched groups - group 1 with obesity without carbohydrate disturbances (n = 66), group 2 with prediabetes (n = 68) and group 3 with newly diagnosed type 2 diabetes (n = 33). Endothelial function was evaluated using EndoPAT, intima media thickness (IMT) was measured on the common carotid artery and ankle-brachial index (ABI) was calculated...
June 8, 2018: Archives of Physiology and Biochemistry
Roshen Borkar, James Rizkalla, Youngmin Kwon, Paul Salama, Maher Rizkalla
Diabetic foot ulcers are systemic diseases that affect all blood vessels within the human body. From major blood vessels to microvasculature, hardening, thickening, and narrowing of blood vessels ultimately results to diminished blood flow to end organs. The detrimental effects of peripheral vascular disease are well recognized across medicine, particularly with regards to diabetic foot ulcers. Diabetic foot ulcers (DFU) are common across all fields of medicine, including but not limited to: orthopedics, vascular surgery, podiatry, general internal medicine, and infectious disease...
June 2018: Journal of Orthopaedics
Jaspreet Sandhu, Charles La Punzina, Ravi Kothuru
This is a case report describing the delayed presentation of injury to all three lower extremity infrapopliteal arteries after a 34 year old male sustained multiple gunshot wounds, including one to his left lower extremity. As part of his initial assessment, ankle brachial index was performed and was found to be abnormal. Further work up for this was delayed due to need for emergent trauma laparotomy. After this procedure, more detailed evaluation with CT angiography of the extremity injury was performed...
June 2018: Trauma Case Reports
Yu-Hsien Lai, Chih-Hsien Wang, Jen-Pi Tsai, Jia-Sian Hou, Chung-Jen Lee, Bang-Gee Hsu
Objective: Peripheral artery disease (PAD) is associated with systemic atherosclerosis and indicates an increased risk of mortality in peritoneal dialysis (PD) patients. A high leptin level accelerates atherosclerosis in apoE-deficient mice. The purpose of this study was to examine the association of serum leptin level and PAD in adult PD patients. Materials and Methods: The clinical characteristics of sixty PD patients recruited from June 2015 to October 2016 were obtained...
April 2018: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
Rebeca A Beraldo, Gabriela C Meliscki, Bruna R Silva, Anderson M Navarro, Valdes R Bollela, André Schmidt, Maria C Foss-Freitas
Background: Body fat redistribution and metabolic abnormalities found in HIV patients receiving highly active antiretroviral therapy (HAART) contribute to an atherogenic profile, increasing cardiovascular disease risk. Objective: We aimed to evaluate adiposity measures/indexes and propose cutoffs associated with predictors of cardiovascular disease risk in HIV patients on HAART. Design: To evaluate cardiovascular disease risk in this cross-sectional study, we conducted electrocardiogram exams and stress electrocardiography, measured the ankle brachial index and blood pressure arterial hypertension, conducted lipid biochemical tests, and measured blood glucose...
June 1, 2018: American Journal of Clinical Nutrition
Ridhima Kapoor, Colby Ayers, Alexis Visotcky, Peter Mason, Jacquelyn Kulinski
The ankle-brachial index (ABI) is a predictor of cardiovascular events, mortality and functional status. Some studies have noted a higher prevalence of peripheral artery disease in females compared to males. Differences in height might account for these observed sex differences, but findings are conflicting. The 2003-2004 National Health and Nutrition Examination Survey (NHANES) cohort includes participants from 15 geographic locations, selected annually to represent the general population. Sample-weighted multivariable linear and logistic regression modeling was performed with ABI as the dependent variable and height and sex as primary exposure variables of interest...
June 1, 2018: Vascular Medicine
L Santoro, A Flex, A Nesci, P M Ferraro, G De Matteis, A Di Giorgio, B Giupponi, L Saviano, G Gambaro, F Franceschi, A Gasbarrini, R Landolfi, A Santoliquido
OBJECTIVE: Most studies on atherosclerotic processes include peripheral arterial disease diagnosis only if patients report symptoms suggestive of peripheral arterial disease and/or an instrumental demonstration of lower limbs perfusion deficit is provided, rather than the sole presence of atherosclerotic lesions localized at lower limbs, this attitude leading to ignore early stages of the disease. To overcome these limitations, we have proposed a new ultrasonographic semiquantitative score to better identify all disease stages...
May 2018: European Review for Medical and Pharmacological Sciences
R Godet, A Bruneau, B Vielle, F Vincent, T Le Tourneau, F Carre, D Hupin, J F Hamel, P Abraham, S Henni
INTRODUCTION: The American Heart Association (AHA) recommendations for diagnosing peripheral artery disease (PAD) after exercise are a decrease > 20% of ankle brachial index (ABI) or > 30 mmHg of ankle systolic blood pressure (ASBP) from resting values. We evaluated ABI and ASBP values during incremental maximal exercise in physically active and asymptomatic patients. METHODS: Patients (n=726) underwent incremental bicycle tests with pre and post-exercise recording of all four limbs arterial pressures simultaneously...
June 1, 2018: Scandinavian Journal of Medicine & Science in Sports
S L Belloch García
OBJECTIVES: To determine the prevalence of previously undiagnosed abdominal aortic aneurysm (AAA) in patients hospitalised in a department of internal medicine, as well as the associated risk factors. PATIENTS AND METHODS: An observational, cross-sectional, single-centre, randomised study was conducted on 241 patients hospitalised in Internal Medicine. The patients were older than 50 years, had no previous diagnosis of AAA and underwent clinical ultrasonography...
May 29, 2018: Revista Clínica Española
Luis García-Ortiz, José I Recio-Rodríguez, Cristina Agudo-Conde, Jose A Maderuelo-Fernandez, Maria C Patino Alonso, Ángela de Cabo-Laso, Carmela Rodriguez-Martín, Jesus Gonzalez-Sanchez, Emiliano Rodriguez-Sanchez, Manuel A Gómez-Marcos
BACKGROUND: The validation of new blood pressure devices with easier use and more rapid data collection may facilitate the incorporation of these measures into clinical practice. We analyze the reliability and validity of Pulse Wave Analysis as reported by a novel wrist-worn device, easy and quick to use, comparing central and peripheral augmentation index (AIx) with the same measures from the SphygmoCor. Additionally, we analyzed clinical relevance through the association of the Pulse Wave Analysis, as reported by a novel wrist-worn device, with other cardiovascular parameters...
May 24, 2018: Journal of Hypertension
Qinzhong Chen, Robert S Rosenson
Lower extremity peripheral arterial disease (LEAD) is increasing in prevalence in low with approximately 202 million people affected with LEAD worldwide. Certain subgroups of individuals (cigarette smokers, diabetics) that are particularly high risk for LEAD and major adverse limb events (MALE). Conventionally, the ankle-brachial index (ABI) is the recommended screening test for LEAD. However, the ABI has several limitations, particularly in patients with diabetes. These limitations include increased measurement variability with severity of LEAD, non-compressible calcified arteries inability to detect arterial disease distal to the ankle precludes assessment of disease in the foot where many ulcers can occur, and underestimation of the extent of microvascular occlusive disease...
May 29, 2018: Cardiovascular Drugs and Therapy
Si Si, Jonathan Golledge, Paul Norman, Mark Nelson, Derek Chew, Zanfina Ademi, Deepak L Bhatt, Gabriel P Steg, Christopher M Reid
BACKGROUND: Compared with other manifestations of cardiovascular disease, peripheral arterial disease (PAD) is under-diagnosed. This study aims to investigate the prevalence, risk profile and cardiovascular outcomes of undiagnosed PAD in Australian general practices. METHOD: A sub-study of the Australian Reduction of Atherothrombosis for Continued Health (REACH) Registry, a prospective cohort study of patients at high risk of atherothrombosis recruited from Australian general practices...
May 8, 2018: Heart, Lung & Circulation
Shun-Li Tian, Kai Zhang, Peng-Cheng Xu
Background peripheral arterial disease (PAD) is a common complication in patients undergoing dialysis, which reduces the quality of life and increases the risk of mortality. Recent literature has documented an association between increased visceral fat (VF) content and a proatherogenic factors in end-stage renal disease. The present study investigated the prevalence of PAD in patients undergoing hemodialysis. PAD was determined as an ankle-brachial index <0.9. Additionally, VF content was determined using multiple frequency bioelectrical impendence analysis...
June 2018: Experimental and Therapeutic Medicine
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