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https://www.readbyqxmd.com/read/28822655/a-national-vascular-quality-initiative-database-comparison-of-hybrid-and-open-repair-for-aortoiliac-femoral-occlusive-disease
#1
Marco Zavatta, Matthew W Mell
OBJECTIVE: We sought to analyze the outcomes of revascularization for aortoiliac-femoral occlusive disease by comparing hybrid repair by endovascular revascularization and open common femoral endarterectomy (ER-CFE) with open aortoiliac reconstruction and CFE (OR-CFE). METHODS: Using the national Society for Vascular Surgery Vascular Quality Initiative database from 2009 to 2015, we identified all patients receiving open or endovascular revascularization of the aortoiliac system and who additionally underwent CFE...
August 16, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28815100/surveillance-of-peripheral-arterial-disease-cases-using-natural-language-processing-of-clinical-notes
#2
Naveed Afzal, Sunghwan Sohn, Christopher G Scott, Hongfang Liu, Iftikhar J Kullo, Adelaide M Arruda-Olson
Peripheral arterial disease (PAD) is a chronic disease that affects millions of people worldwide and yet remains underdiagnosed and undertreated. Early detection is important, because PAD is strongly associated with an increased risk of mortality and morbidity. In this study, we built a PAD surveillance system using natural language processing (NLP) for early detection of PAD from narrative clinical notes. Our NLP algorithm had excellent positive predictive value (0.93) and identified 41% of PAD cases before the initial ankle-brachial index (ABI) test date while in 12% of cases the NLP algorithm detected PAD on the same date as the ABI (the gold standard for comparison)...
2017: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/28813772/pilot-study-to-determine-safety-and-efficacy-of-paclitaxel-infusion-in-de-novo-peripheral-lesions-using-the-atrium-clearway-balloon
#3
Joseph Anderson, Laura Danielson, Jodan Anderson, Katie Pohlson, Tyler Remund, Chad Laurich, Greg Schultz, Angelo Santos, Gopinath Mani, Patrick Kelly, Andrea Shermann
OBJECTIVE: To evaluate the safety and efficacy of a one-time infusion of paclitaxel through an Atrium ClearWay balloon in infra inguinal de novo peripheral lesions. METHODS: This is a single-center prospective study looking at treatment of 50 limbs. Treatment includes standard infra inguinal endovascular revascularization followed by a pre-prescribed infusion of paclitaxel. Control is standard reintervention without subsequent paclitaxel infusion. Patients were followed at one, four, and 10 months with ankle-brachial index (ABI)s, arterial duplex of the treated limb, and Rutherford classification stage measured before and after procedures and at each follow-up...
March 2017: South Dakota Medicine: the Journal of the South Dakota State Medical Association
https://www.readbyqxmd.com/read/28813083/ankle-brachial-index-and-diabetic-neuropathy-study-of-225-patients
#4
Liliana Chevtchouk, Marcio Heitor Stelmo da Silva, Osvaldo José Moreira do Nascimento
Objective: To evaluate neuropathic pain and peripheral vascular disease in diabetics and compare this with the length of time since diagnosis in type 1, and type 2 diabetes. Methods: A cross-sectional study with 225 diabetics chosen from their responses on the DN4 questionnaire, who were then evaluated with the ankle-brachial index (ABI), separating type 1 diabetes from type 2 diabetes. Results: A higher incidence of neuropathic pain in those over 60 years of age showed an ABI > 1...
August 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28810647/limb-graft-occlusion-following-endovascular-aortic-repair-incidence-causes-treatment-and-prevention-in-a-study-cohort
#5
Guoquan Wang, Shuiting Zhai, Tianxiao Li, Xuan Li, Danghui Lu, Bo Wang, Dongbin Zhang, Shuaitao Shi, Zhidong Zhang, Kai Liang, Kewei Zhang, Xiaoyang Fu, Kun Li, Weixiao Li
The present study investigated the incidence, causes, treatment and prevention of limb graft occlusion following endovascular aortic repair (EVAR). A total of 66 cases of abdominal aortic aneurysm receiving EVAR at our department from January 2005 to December 2013 were enrolled. After EVAR, patients received routine antiplatelet therapy of 75 mg PLAVIX for 6 months and then 100 mg Aspirin for another 6 months by oral administration. According to previous clinical experiences, antiplatelet therapy is able to effectively reduce the incidence of iliac occlusion after EVAR...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28803825/cardiovascular-events-after-exposure-to-nilotinib-in-chronic-myeloid-leukemia-long-term-follow-up
#6
Nazanin Aghel, Jeffrey Howard Lipton, Eshetu G Atenafu, Dennis Dong Hwan Kim, Diego Hernan Delgado
INTRODUCTION: Nilotinib is a highly effective tyrosine kinase inhibitor in the treatment of chronic myeloid leukemia (CML). However, reports of cardiovascular toxicities caused by nilotinib have recently raised critical concerns. The aim of the present study was to evaluate the incidence of cardiovascular events (CVEs) and frequency of asymptomatic peripheral arterial disease (PAD) after long-term exposure to nilotinib. PATIENTS AND METHODS: In the present retrospective cohort, we evaluated the incidence of CVEs in 63 CML patients treated with nilotinib...
July 15, 2017: Clinical Lymphoma, Myeloma & Leukemia
https://www.readbyqxmd.com/read/28797281/the-efficacy-of-transcutaneous-electrical-nerve-stimulation-on-the-improvement-of-walking-distance-in-patients-with-peripheral-arterial-disease-with-intermittent-claudication-study-protocol-for-a-randomised-controlled-trial-the-tens-pad-study
#7
Florent Besnier, Jean-Michel Sénard, Vincent Grémeaux, Mélanie Riédel, Damien Garrigues, Thibaut Guiraud, Marc Labrunée
BACKGROUND: In patients with peripheral arterial disease (PAD), walking improvements are often limited by early pain onset due to vascular claudication. It would thus appear interesting to develop noninvasive therapeutic strategies, such as transcutaneous electrical nerve stimulation (TENS), to improve the participation of PAD patients in rehabilitation programmes, and thus improve their quality of life. Our team recently tested the efficacy of a single 45-min session of 10-Hz TENS prior to walking...
August 10, 2017: Trials
https://www.readbyqxmd.com/read/28795888/effective-wound-bed-preparation-using-maggot-debridement-therapy-for-patients-with-critical-limb-ischaemia
#8
A Nishijima, M Gosho, R Yoshida, S Yanagibayashi, M Takikawa, J Nishijima, M Sekido, N Yamamoto
OBJECTIVE: Patients with critical limb ischaemia (CLI) lack sufficient blood flow in to the limb, which leads to difficulties in the normal wound healing process. Therefore, maggot debridement therapy (MDT) has not generally been recommended for CLI patients. We evaluated the effectiveness of wound bed preparation by MDT in CLI patients who had undergone mid-foot amputation. METHODS: Patients who underwent mid-foot amputation after angioplasty between April 2014 and October 2016 were retrospectively investigated by classifying them into an MDT group or a conventional treatment group...
August 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28794054/cardiovascular-event-prediction-by-machine-learning-the-multi-ethnic-study-of-atherosclerosis
#9
Bharath Ambale-Venkatesh, Xiaoying Yang, Colin O Wu, Kiang Liu, W G Hundley, Robyn L McClelland, Antoinette S Gomes, Aaron R Folsom, Steven Shea, Eliseo Guallar, David A Bluemke, João A Lima
Rationale: Machine learning may be useful to characterize cardiovascular risk, predict outcomes and identify biomarkers in population studies. Objective: To test the ability of random survival forests (RF), a machine learning technique, to predict six cardiovascular outcomes in comparison to standard cardiovascular risk scores. Methods and Results: We included participants from the Multi-Ethnic Study of Atherosclerosis (MESA). Baseline measurements were used to predict cardiovascular outcomes over 12 years of follow-up...
August 9, 2017: Circulation Research
https://www.readbyqxmd.com/read/28793000/intermittent-claudication-and-severe-renal-artery-stenosis-are-independently-associated-in-hypertensive-patients-referred-for-renal-arteriography
#10
Thiago Andrade Macedo, Luciano Ferreira Drager, Rodrigo Pinto Pedrosa, Henrique Cotchi Simbo Muela, Valeria Costa-Hong, Luiz Junia Kajita, Luiz Aparecido Bortolotto
OBJECTIVE: The purpose of this study was to evaluate the association between the presence of clinical symptoms of peripheral artery disease and severe renal artery stenosis in patients referred for renal angiography. METHOD: We included 82 patients with clinical suspicion of renovascular hypertension and performed an imaging investigation (renal Doppler ultrasound and/or renal scintigraphy) for possible renal artery stenosis. All patients underwent renal arteriography and were examined for peripheral artery disease based on the presence of intermittent claudication and ankle-brachial index test results...
July 2017: Clinics
https://www.readbyqxmd.com/read/28781862/acute-arterial-occlusion-after-total-knee-arthroplasty-a-case-report
#11
Kei Inomata, Ichiro Sekiya, Koji Otabe, Tomomasa Nakamura, Masafumi Horie, Hideyuki Koga, Toshifumi Watanabe, Takeshi Muneta
Popliteal artery occlusion after total knee arthroplasty is rare (0.03-0.17%) but can lead to amputation if overlooked. We should carefully assess vascular patency by Doppler ultrasound and ankle brachial pressure index (ABPI) measurement before and after total knee arthroplasty (TKA) operation.
August 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28781301/ankle-brachial-index-for-the-prognosis-of-cardiovascular-disease-in-patients-with-mild-renal-insufficiency
#12
Hitoshi Nishimura, Takashi Miura, Masatoshi Minamisawa, Yasushi Ueki, Naoyuki Abe, Naoto Hashizume, Tomoaki Mochidome, Mikiko Harada, Kunihiko Shimizu, Wataru Shoin, Koji Yoshie, Yasutaka Oguchi, Soichiro Ebisawa, Hirohiko Motoki, Atsushi Izawa, Jun Koyama, Uichi Ikeda, Koichiro Kuwahara
Objective A low ankle-brachial index (ABI) is a known predictor for future cardiovascular events and mortality in patients with chronic kidney disease (CKD). While most prior studies have defined CKD as an estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m(2), recent reports have suggested that the cardiovascular risk may be increased even in early stages of renal insufficiency. We hypothesized that a low ABI may predict future cardiovascular morbidity and mortality in patients with mild impairment of the renal function...
August 1, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28777936/comparison-of-non-traditional-biomarkers-and-combinations-of-biomarkers-for-vascular-risk-prediction-in-people-with-type-2-diabetes-the-edinburgh-type-2-diabetes-study
#13
Anna H Price, Christopher J Weir, Paul Welsh, Stela McLachlan, Mark W J Strachan, Naveed Sattar, Jackie F Price
BACKGROUND AND AIMS: We aimed at comparing the impact of multiple non-traditional biomarkers (ankle brachial pressure index (ABI), N-terminal pro-brain natriuretic peptide (NT-proBNP), high sensitivity cardiac troponin (hs-cTnT), gamma-glutamyl transpeptidase (GGT) and four markers of systemic inflammation), both individually and in combination, on cardiovascular risk prediction, over and above traditional risk factors incorporated in the QRISK2 score, in older people with type 2 diabetes...
July 12, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28756044/association-between-arterial-stiffness-and-peripheral-artery-disease-as-measured-by-radial-artery-tonometry
#14
Greg J Zahner, Magdalena A Gruendl, Kimberly A Spaulding, Melinda S Schaller, Nancy K Hills, Warren J Gasper, S Marlene Grenon
OBJECTIVE: Arterial stiffness and peripheral artery disease (PAD) are both associated with an elevated risk of major adverse cardiac events; however, the association between arterial stiffness and PAD is less well characterized. The goal of this study was to examine the association between parameters of radial artery tonometry, a noninvasive measure of arterial stiffness, and PAD. METHODS: We conducted a cross-sectional study of 134 vascular surgery outpatients (controls, 33; PAD, 101) using arterial applanation tonometry...
July 26, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28754427/abnormally-high-ankle-brachial-index-is-associated-with-all-cause-and-cardiovascular-mortality-the-regicor-study
#15
A Velescu, A Clara, R Martí, R Ramos, S Perez-Fernandez, L Marcos, M Grau, I R Degano, J Marrugat, R Elosua
INTRODUCTION: The clinical significance of a high ankle brachial index (ABI) and its relationship to cardiovascular disease (CVD) and mortality is controversial. The aim of this study was to estimate the association between abnormally high ABI ≥ 1.4 and coronary heart disease (CHD), cerebrovascular disease, and all-cause mortality in a Mediterranean population without CVD. METHODS: A prospective population based cohort study of 6352 subjects was followed up for a median 6...
July 25, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28753096/conservative-treatment-of-patients-with-thromboangiitis-obliterans-or-cannabis-associated-arteritis-presenting-with-critical-lower-limb-ischaemia
#16
George Galyfos, Stavros Kerasidis, Georgios Kastrisios, Sotirios Giannakakis, Ioannis Sachmpazidis, Christiana Anastasiadou, Georgios Geropapas, Anastasios Papapetrou, Gerasimos Papacharalampous, Chrisostomos Maltezos
BACKGROUND: Proper management of patients with thromboangiitis obliterans (TAO) or cannabis-associated arteritis (CAA), presenting with critical lower limb ischaemia (CLI) remains controversial, and data are limited. PATIENTS AND METHODS: Patients with TAO or CAA presenting with CLI between 2011 and 2016 were retrospectively evaluated. Patients requiring primary intervention were excluded. Conservative treatment included: (a) weight-adjusted bemiparin plus six hours/day intravenous iloprost for 28 days, (b) aspirin (100 mg/day) plus cilostazol (100 mg twice/day) after discharge, and (c) strict recommendations/monitoring for smoking cessation...
July 28, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/28734461/risk-factors-for-mortality-among-individuals-with-peripheral-arterial-disease
#17
Stephen M Amrock, Cherrie Z Abraham, Enjae Jung, Pamela B Morris, Michael D Shapiro
Morbidity and mortality from peripheral arterial disease (PAD) continues to increase. Traditional cardiovascular risk factors are implicated in the development of PAD, yet the extent to which those risk factors correlate with mortality in such patients remains insufficiently assessed. Using data from the 1999 to 2004 National Health and Nutrition Examination Survey, Cox proportional hazards models were used to examine the association of cardiovascular risk factors and all-cause and cardiovascular mortality...
June 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28733607/two-year-follow-up-of-vascular-events-in-peripheral-arterial-disease-treated-with-antiplatelet-agents-a-prospective-observational-multicenter-cohort-study-season
#18
Yukihito Higashi, Tetsuro Miyata, Hiroshi Shigematsu, Hideki Origasa, Masatoshi Fujita, Hiroshi Matsuo, Hiroaki Naritomi, Hiroaki Matsuda, Masahide Nakajima, Hideto Awano
The present analysis was intended to evaluate the real-world management of peripheral arterial disease (PAD) in Asia, and to explore cardiovascular events in patients with PAD undergoing antiplatelet therapy over 2 years of follow-up. The Surveillance of cardiovascular Events in Antiplatelet-treated arteriosclerosis Obliterans patients in JapaN (SEASON) registry is a prospective observational multicenter study of cardiovascular events in antiplatelet-treated patients with PAD in Japan. The SEASON registry included 11,375 patients who were scheduled to receive treatment for PAD...
July 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28729408/femoral-artery-atherosclerosis-is-associated-with-physical-function-across-the-spectrum-of-the-ankle-brachial-index-the-san-diego-population-study
#19
Christina L Wassel, Alicia M Ellis, Natalie C Suder, Emma Barinas-Mitchell, Dena E Rifkin, Nketi I Forbang, Julie O Denenberg, Antoinette M Marasco, Belinda J McQuaide, Nancy S Jenny, Matthew A Allison, Joachim H Ix, Michael H Criqui
BACKGROUND: The ankle-brachial index (ABI) is inadequate to detect early-stage atherosclerotic disease, when interventions to prevent functional decline may be the most effective. We determined associations of femoral artery atherosclerosis with physical functioning, across the spectrum of the ABI, and within the normal ABI range. METHODS AND RESULTS: In 2007-2011, 1103 multiethnic men and women participated in the San Diego Population Study, and completed all components of the summary performance score...
July 20, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28729250/stellarex-drug-coated-balloon-for-treatment-of-femoropopliteal-disease-12-month-outcomes-from-the-randomized-illumenate-pivotal-and-pharmacokinetic-studies
#20
Prakash Krishnan, Peter Faries, Khusrow Niazi, Ash Jain, Ravish Sachar, William B Bachinsky, Joseph A Cardenas, Martin Werner, Marianne Brodmann, J A Mustapha, Carlos I Mena-Hurtado, Michael R Jaff, Andrew H Holden, Sean P Lyden
Background -Drug-coated balloons (DCB) are a predominant revascularization therapy for symptomatic femoropopliteal artery disease. Due to differences in excipients, paclitaxel dose and coating morphologies, varying clinical outcomes have been observed with different DCBs. We report the results of two studies investigating the pharmacokinetic (PK) and clinical outcomes of a new DCB to treat femoropopliteal disease. Methods -In the ILLUMENATE Pivotal Study, 300 symptomatic patients (Rutherford class 2-4), were randomized to DCB (N=200) or standard angioplasty (PTA) (N=100)...
July 20, 2017: Circulation
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