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https://www.readbyqxmd.com/read/28528401/cardiovascular-disease-biomarkers-are-associated-with-declining-renal-function-in-type-2-diabetes
#1
Sara J Jenks, Bryan R Conway, Stela McLachlan, Wei Leng Teoh, Rachel M Williamson, David J Webb, Paul Welsh, Naveed Sattar, Mark W J Strachan, Jackie F Price
AIMS/HYPOTHESIS: We investigated whether biochemical cardiovascular risk factors and/or markers of subclinical cardiovascular disease were associated with the development of reduced renal function in people with type 2 diabetes. METHODS: A cohort of 1066 Scottish men and women aged 60-74 years with type 2 diabetes from the Edinburgh Type 2 Diabetes Study were followed up for a median of 6.7 years. New-onset reduced renal function was defined as two eGFRs <60 ml(-1) min(-1) (1...
May 20, 2017: Diabetologia
https://www.readbyqxmd.com/read/28526782/acute-impact-of-drinking-coffee-on-the-cerebral-and-systemic-vasculature
#2
Takuro Washio, Hiroyuki Sasaki, Shigehiko Ogoh
Previous studies have suggested that the risk of ischemic stroke increases immediately after drinking coffee. Indeed, drinking coffee, that is, caffeine, acutely increases arterial stiffness as well as blood pressure and peripheral vascular resistance. On the other hand, it has been reported that arterial stiffening is associated with elevation in the pulsatility index (PI) of cerebral blood flow (CBF), which increases the risk of brain disease. However, the effect of drinking coffee on the PI of the CBF and its interaction with arterial stiffness remain unknown...
May 2017: Physiological Reports
https://www.readbyqxmd.com/read/28522699/greater-frequency-of-fruit-and-vegetable-consumption-is-associated-with-lower-prevalence-of-peripheral-artery-disease
#3
Sean P Heffron, Caron B Rockman, Mark A Adelman, Eugenia Gianos, Yu Guo, Jin Feng Xu, Jeffrey S Berger
OBJECTIVE: Although fruit and vegetable (F&V) consumption is associated with lower risk of coronary heart disease and stroke, its association with peripheral artery disease (PAD) is less certain. We, thus, sought to characterize F&V intake and investigate the association between F&V consumption and presence of PAD in a large community sample. APPROACH AND RESULTS: Self-referred participants at >20 000 US sites who completed medical and lifestyle questionnaires were evaluated by screening ankle brachial indices for PAD (ankle brachial index ≤0...
May 18, 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/28522299/most-advisable-strategy-in-search-of-asymptomatic-target-organ-damage-in-hypertensive-patients
#4
J Abellán-Huerta, L Prieto-Valiente, L Consuegra-Sánchez, S Montoro-García, A B Salguero-Merino, R Morales-López, J Abellán-Alemán, F Soria-Arcos
OBJECTIVE: To evaluate the diagnostic potential of seven examinations in order to define the most suitable strategy for target organ damage (TOD) search in hypertensive patients. METHODS: This is a descriptive, cross-sectional study. 153 consecutive treated and essential hypertensive patients were enrolled. Patients with established cardiovascular or chronic renal disease (stage ≥4) were excluded. TOD search was assessed by: glomerular filtration rate (GFR), albumin/creatinine ratio (ACR), electrocardiogram (ECG), echocardiogram (ECO), ankle-brachial index (ABI), pulse wave velocity (PWV), and carotid ultrasound (intima media thickness and presence of plaques)...
May 15, 2017: Hipertensión y Riesgo Vascular
https://www.readbyqxmd.com/read/28513244/different-relationship-between-physical-activity-arterial-stiffness-and-metabolic-status-in-obese-subjects
#5
Hyung Joon Joo, Sang-A Cho, Jae-Young Cho, Seunghun Lee, Jae Hyung Park, Cheol Woong Yu, Soon Jun Hong, Do-Sun Lim
BACKGROUND: Although the relationship between physical activity and arterial stiffness has been shown in healthy persons, it remains controversial in obese persons. METHODS: From January to September 2014, we evaluated 795 obese subjects from 25 public health centers in Seoul. We compared physical activity and brachial-ankle pulse wave velocity (baPWV) between obese subjects with metabolic syndrome (MetS) (MO) and obese subjects without MetS (NMO). RESULTS: The MO group had more men, higher body mass index (BMI), higher fasting glucose level, lower high-density lipoprotein-cholesterol level, and higher triglyceride level...
May 17, 2017: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/28507296/sleep-disorder-an-independent-risk-associated-with-arterial-stiffness-in-menopause
#6
Yang Zhou, Ruwei Yang, Changbin Li, Minfang Tao
As women age and go through menopause, they suffer a higher incidence of sleep disorder, cardiovascular morbidity and mortality. In addition, evidences suggested that sleep disorder was an important pathological indicator for coronary heart disease. However, the relationship between different menopausal status, sleep disorder and cardiovascular diseases was unclear. Thus, we aim to assess the association between sleep disorder with arterial stiffness in females of 40-60 years free of cardiovascular diseases through self-administered Pittsburgh Sleep Quality Index (PSQI) and brachial-ankle pulse wave velocity (baPWV)...
May 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28502918/ability-of-the-ankle-brachial-index-and-brachial-ankle-pulse-wave-velocity-to-predict-the-3-month-outcome-in-patients-with-non-cardioembolic-stroke
#7
Hayato Matsushima, Naohisa Hosomi, Naoyuki Hara, Takeshi Yoshimoto, Shuichiro Neshige, Ryuhei Kono, Takahiro Himeno, Shinichi Takeshima, Kazuhiro Takamatsu, Yutaka Shimoe, Taisei Ota, Hirofumi Maruyama, Toshiho Ohtsuki, Masaru Kuriyama, Masayasu Matsumoto
AIM: Both the ankle brachial index (ABI) and brachial-ankle pulse wave velocity (baPWV) are surrogates for atherosclerosis. In this study, we aimed to evaluate the ability of ABI and baPWV to predict stroke outcome in patients with first-ever non-cardioembolic stroke. METHODS: This study included consecutive patients with first-ever non-cardioembolic stroke admitted within 1 week after onset to Ota Memorial Hospital between January 2011 and December 2013. Baseline characteristics and National Institutes of Health stroke scale scores at admission were noted...
May 15, 2017: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/28502539/racial-differences-in-functional-decline-in-peripheral-artery-disease-and-associations-with-socioeconomic-status-and-education
#8
Mary M McDermott, Tamar S Polonsky, Melina R Kibbe, Lu Tian, Lihui Zhao, William H Pearce, Ying Gao, Jack M Guralnik
OBJECTIVE: The objective of this study was to determine whether blacks with lower extremity peripheral artery disease (PAD) have faster functional decline than whites with PAD. METHODS: Participants with ankle-brachial index <0.90 were identified from Chicago medical centers and observed longitudinally. Mobility impairment and the 6-minute walk were assessed at baseline and every 6 to 12 months. Mobility loss was defined as becoming unable to walk up and down a flight of stairs or to walk ¼ mile without assistance...
May 11, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28501727/methods-to-evaluate-arterial-structure-and-function-in-children-state-of-the-art-knowledge
#9
REVIEW
Piotr Skrzypczyk, Małgorzata Pańczyk-Tomaszewska
BACKGROUND: With increasing rates of hypertension, obesity, and diabetes in the pediatric population, wide available, and reproducible methods are necessary to evaluate arterial structure and function in children and adolescents. METHODS: MEDLINE/Pubmed was searched for articles published in years 2012-2017 on methodology of, current knowledge on, and limitations of the most commonly used methods to evaluate central, proximal and coronary arteries, as well as endothelial function in pediatric patients...
May 11, 2017: Advances in Medical Sciences
https://www.readbyqxmd.com/read/28493614/accuracy-of-physical-exam-ankle-brachial-index-and-ultrasonography-in-the-diagnosis-of-arterial-injury-in-patients-with-penetrating-extremity-trauma-a-systematic-review-and-meta-analysis
#10
Ian S deSouza, Roshanak Benabbas, Sean McKee, Bardiya Zangbar, Ashika Jain, Lorenzo Paladino, Leon Boudourakis, Richard Sinert
BACKGROUND: Penetrating Extremity Trauma (PET) may result in arterial injury, a rare but limb- and life-threatening surgical emergency. Accurate and timely diagnosis is vital to enable potential intervention and prevent significant morbidity. OBJECTIVES: Using a systematic review/meta-analysis approach, we determined the utility of Physical Examination (exam), Ankle-Brachial Index (ABI), and Ultrasonography (US) in the diagnosis of arterial injury in ED patients who have sustained PET...
May 11, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28490753/wbc-count-predicts-the-risk-of-new-onset-peripheral-arterial-disease-in-a-chinese-community-based-population
#11
Yuxi Li, Fangfang Fan, Jia Jia, Jianping Li, Yong Huo, Yan Zhang
This longitudinal cohort study investigated whether peripheral WBC counts could predict peripheral arterial disease (PAD) incidence after a 2.3-year follow-up in a Chinese community-based population without PAD at baseline. A total of 3555 Chinese subjects without fever and PAD at baseline from an atherosclerosis cohort were included in our analysis. The ankle brachial index (ABI) was measured, and PAD was defined as an ABI <0.9. Multivariate regression models were used to evaluate the association of WBC count and new-onset PAD...
May 11, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28488106/treatment-evaluation-of-flow-limiting-stenoses-of-the-superficial-femoral-and-popliteal-artery-by-parametric-color-coding-analysis-of-digital-subtraction-angiography-series
#12
Michael Kostrzewa, Kerim Kara, Lothar Pilz, Hannelore Mueller-Muertz, Nils Rathmann, Stefan O Schoenberg, Steffen J Diehl
PURPOSE: To evaluate the hemodynamic effect of percutaneous transluminal intervention (PTI) on stenosis of the superficial femoral (SFA) and popliteal arteries (PA) using time-density curves (TDCs) derived from digital subtraction angiography (DSA) series in correlation with ultrasound peak systolic velocity ratio (PSVR) and ankle brachial index (ABI). MATERIALS AND METHODS: DSA series of SFA or PA of patients with symptomatic peripheral arterial occlusive disease was obtained with a flat-panel angiography system with intention-to-treat...
May 9, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28483016/change-of-serum-angiopoietin-like-protein-2-and-its-significance-in-patients-with-arteriosclerotic-occlusion
#13
Yue Liang, Hao Nie, Hualiang Ren, Fangda Li, Cui Tian, Huihua Li, Yuehong Zheng
Objective To investigated the changes of angiopoietin-like protein 2(Angptl2) in patients with arteriosclerotic occlusion (ASO). Methods A total of 140 subjects including 75 ASO patients (ASO group) and 65 healthy subjects (control group) were enrolled in this study. Angptl2 and adiponectin were evaluated by using enzyme-linked immunosorbent assay. Biochemical data and high sensitive C reactive protein were measured and recorded as well. Results Compared to the control group,the ASO group presented with significantly higher level of plasma Angptl2 [(13...
April 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/28479452/cumulative-number-of-treatment-interventions-predicts-health-related-quality-of-life-in-patients-with-critical-limb-ischemia
#14
Matthew A Corriere, Matthew P Goldman, Ryan Barnard, Santiago Saldana, Jeanette M Stafford, Douglas Easterling, Edward H Ip, Gregory L Burke
INTRODUCTION: Health-related quality of life (QOL) is usually assessed after a defined interval following a single intervention, but critical limb ischemia (CLI) is a chronic condition where multiple interventions are often required over a patient's lifetime. We hypothesized that the impact of CLI treatment interventions on QOL is diminished in the setting of multiple previous interventions. To test this hypothesis, we performed a cross-sectional study evaluating associations between cumulative number of previous PAD treatment interventions and QOL adjusting for both comorbidity and disease severity...
May 4, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28475443/evaluation-of-skin-perfusion-pressure-to-assess-refractory-foot-ulcers
#15
M Kawai, S Mihara, S Takahagi, K Iwamoto, T Hiragun, M Hide
OBJECTIVE: The number of patients with foot gangrene caused by critical ischaemia and severe infection is increasing significantly in developed countries. The measurement of perilesional skin blood flow by skin perfusion pressure (SPP) is useful to select the appropriate treatment of gangrenous lesions, in that it is not affected by calcifications of blood vessels. However, the prognosis of a foot ulcer may also be affected by the level of blood sugar and infections. This study aimed to validate the use of SPP in cases of foot gangrene and ulcers in patients with and without diabetes mellitus (DM) and infection...
May 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28473094/acr-appropriateness-criteria-%C3%A2-vascular-claudication-assessment-for-revascularization
#16
Osmanuddin Ahmed, Michael Hanley, Shelby J Bennett, Ankur Chandra, Benoit Desjardins, Kenneth L Gage, Marie D Gerhard-Herman, Michael Ginsburg, Heather L Gornik, Isabel B Oliva, Michael L Steigner, Richard Strax, Nupur Verma, Frank J Rybicki, Karin E Dill
Vascular claudication is a symptom complex characterized by reproducible pain and weakness in an active muscle group due to peripheral arterial disease. Noninvasive hemodynamic tests such as the ankle brachial index, toe brachial index, segmental pressures, and pulse volume recordings are considered the first imaging modalities necessary to reliably establish the presence and severity of arterial obstructions. Vascular imaging is consequently used for diagnosing individual lesions and triaging patients for medical, percutaneous, or surgical intervention...
May 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28468953/prevalence-of-tibial-artery-and-pedal-arch-patency-by-angiography-in-patients-with-critical-limb-ischemia-and-noncompressible-ankle-brachial-index
#17
Mandeep Singh Randhawa, Grant W Reed, Kevin Grafmiller, Heather L Gornik, Mehdi H Shishehbor
BACKGROUND: Approximately 20% of patients undergoing ankle brachial index testing for critical limb ischemia have noncompressible vessels because of tibial artery calcification. This represents a clinical challenge in determining tibial artery patency. We sought to identify the prevalence of tibial artery and pedal arch patency by angiography in these patients. METHODS AND RESULTS: One hundred twenty-five limbs (of 89 patients) with critical limb ischemia and ankle brachial index ≥1...
May 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28466760/peripheral-arterial-disease-preoperatively-may-predict-graft-failure-and-mortality-in-kidney-transplant-recipients
#18
Salma I Patel, Harini A Chakkera, Paul W Wennberg, David A Liedl, Fadi Alrabadi, Stephen S Cha, Darren D Hooley, Hatem Amer, Hani M Wadei, Fadi E Shamoun
Patients with end-stage renal disease undergoing kidney transplant often have diffuse atherosclerosis and high cardiovascular morbidity and mortality rates. We analyzed the correlation of peripheral arterial disease (PAD), here quantified by an abnormal ankle-brachial index (ABI) measured within the 5 years prior to kidney transplant, with graft failure and mortality rates (primary end points) after adjusting for known cardiovascular risk factors (age, sex, smoking history, hypertension, diabetes, stroke, known coronary artery disease or heart failure, years of dialysis)...
March 1, 2017: Vascular Medicine
https://www.readbyqxmd.com/read/28466409/effects-of-pitavastatin-on-walking-capacity-and-cd34-133-cell-number-in-patients-with-peripheral-artery-disease
#19
Kenshiro Arao, Takanori Yasu, Yasuhiro Endo, Toshikazu Funazaki, Yoshimi Ota, Kazunori Shimada, Eiichi Tokutake, Naoki Naito, Bonpei Takase, Minoru Wake, Nahoko Ikeda, Yasuto Horie, Hiroyuki Sugimura, Shin-Ichi Momomura, Masanobu Kawakami
This multi-center prospective non-randomized comparative study investigated the effects of pitavastatin in patients with peripheral artery disease (PAD) in terms of exercise tolerance capacities and peripheral CD34(+)/133(+) cell numbers. At baseline, a peripheral blood test was administered to 75 patients with PAD, along with a treadmill exercise test using the Skinner-Gardner protocol to measure asymptomatic walking distance (AWD) and maximum walking distance (MWD). Each patient was assigned to a 6-month pitavastatin treatment group (n = 53) or a control group (n = 22), according to the patient's preference...
May 2, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28463782/asymptomatic-polyvascular-disease-and-the-risks-of-cardiovascular-events-and-all-cause-death
#20
Qian Zhang, Anxin Wang, Shufeng Zhang, Na Li, Shengyun Chen, Yaqing Zhang, Yong Zhou, Shouling Wu, Xingquan Zhao
BACKGROUND AND AIMS: Atherosclerosis is a diffuse and systemic disease. We aimed to assess prevalence and outcome of extracoronary polyvascular disease (polyVD) in the asymptomatic Chinese community population. METHODS: A random sample of 5440 participants aged 40 years or older were enrolled in the Asymptomatic Polyvascular Abnormalities Community Study from 2010 to 2011. Intracranial artery stenosis, extracranial artery stenosis, and lower extremity artery disease were detected by transcranial Doppler and duplex sonography, and by calculating the ankle brachial index...
April 21, 2017: Atherosclerosis
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