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https://www.readbyqxmd.com/read/27936071/foot-conditions-among-homeless-persons-a-systematic-review
#1
Matthew J To, Thomas D Brothers, Colin Van Zoost
INTRODUCTION: Foot problems are common among homeless persons, but are often overlooked. The objectives of this systematic review are to summarize what is known about foot conditions and associated interventions among homeless persons. METHODS: A literature search was conducted on MEDLINE (1966-2016), EMBASE (1947-2016), and CINAHL (1982-2016) and complemented by manual searches of reference lists. Articles that described foot conditions in homeless persons or associated interventions were included...
2016: PloS One
https://www.readbyqxmd.com/read/27936006/prognostic-value-of-red-blood-cell-distribution-width-in-non-cardiovascular-critically-or-acutely-patients-a-systematic-review
#2
Rubin Luo, Jian Hu, Libing Jiang, Mao Zhang
BACKGROUND: RDW (red cell distribution width) has been reported to been associated with the prognosis of patients with cardiovascular diseases. However, RDW is often overlooked by clinicians in treating patients with non-cardiovascular diseases, especially in an emergency. The objective of this systematic review is to explore the prognostic value of RDW in non-cardiovascular emergencies. METHODS: PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials were systematically searched from their inception to December 31, 2015...
2016: PloS One
https://www.readbyqxmd.com/read/27935991/a-competency-model-for-clinical-physicians-in-china-a-cross-sectional-survey
#3
Zhuang Liu, Lei Tian, Qing Chang, Baozhi Sun, Yuhong Zhao
BACKGROUND: Around the world, regulatory bodies have taken the lead in determining the competencies required to become a physician. As a first step in addressing this project, it was decided to develop a set of core competencies that were unique to China and that might serve as a basis for medical education. The purpose of this paper was to construct a competency model for clinical physicians in China. METHODS: Data was collected using a cross-sectional survey of 6247 clinicians from seven administrative regions (31 provinces, autonomous regions and municipalities directly under the central government) in China...
2016: PloS One
https://www.readbyqxmd.com/read/27935937/let-s-not-waste-time-using-temporal-information-in-clustered-activity-estimation-with-spatial-adjacency-restrictions-caesar-for-parcellating-fmri-data
#4
Ronald J Janssen, Pasi Jylänki, Marcel A J van Gerven
We have proposed a Bayesian approach for functional parcellation of whole-brain FMRI measurements which we call Clustered Activity Estimation with Spatial Adjacency Restrictions (CAESAR). We use distance-dependent Chinese restaurant processes (dd-CRPs) to define a flexible prior which partitions the voxel measurements into clusters whose number and shapes are unknown a priori. With dd-CRPs we can conveniently implement spatial constraints to ensure that our parcellations remain spatially contiguous and thereby physiologically meaningful...
2016: PloS One
https://www.readbyqxmd.com/read/27935036/sentinel-node-metastasis-mitotic-rate-sn-mmr-as-a-prognostic-indicator-of-rapidly-progressing-disease-in-patients-with-sentinel-node-positive-melanomas
#5
Cornelia Baum, Christel Weiss, Christoffer Gebhardt, Jochen Utikal, Alexander Marx, Wolfgang Koenen, Cyrill Géraud
Risk stratification of sentinel lymph node biopsy (SNB)-positive patients with malignant melanoma differs among current classification systems. To improve classification of patients with rapidly progressive disease who may profit from adjuvant therapy with novel immune or targeted treatment modalities, a single-center retrospective analysis was performed including all melanoma patients diagnosed with a positive SN at a university-based skin cancer center over a 10-year period (2002-2012) (96 of 419 patients)...
December 9, 2016: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/27934674/should-attendance-be-required-in-lecture-classrooms-in-dental-education-two-viewpoints-viewpoint-1-attendance-in-the-lecture-classroom-should-be-required-and-viewpoint-2-attendance-should-not-be-required-in-the-lecture-classroom
#6
Christopher W Cutler, Mary Parise, Ana Lucia Seminario, Maria Jose Cervantes Mendez, Wilhelm Piskorowski, Renato Silva
This Point/Counterpoint discusses the long-argued debate over whether lecture attendance in dental school at the predoctoral level should be required. Current educational practice relies heavily on the delivery of content in a traditional lecture style. Viewpoint 1 asserts that attendance should be required for many reasons, including the positive impact that direct contact of students with faculty members and with each other has on learning outcomes. In lectures, students can more easily focus on subject matter that is often difficult to understand...
December 2016: Journal of Dental Education
https://www.readbyqxmd.com/read/27934611/a-multicentre-european-registry-to-evaluate-the-direct-flow-medical-transcatheter-aortic-valve-system-for-the-treatment-of-patients-with-severe-aortic-stenosis
#7
Christoph K Naber, Stylianos A Pyxaras, Hüseyin Ince, Peter Frambach, Antonio Colombo, Christian Butter, Fernando Gatto, Ulrich Hink, Georg Nickenig, Giuseppe Bruschi, Guus Brueren, Didier Tchétché, Peter Den Heijer, Wolfgang Schillinger, Smita Scholtz, Jan Van der Heyden, Thierry Lefèvre, Martine Gilard, Karl-Heinz Kuck, Joachim Schofer, Dimitar Divchev, Helmut Baumgartner, Federico Asch, Daniel Wagner, Azeem Latib, Federico De Marco, Stephan Kische
AIMS: Our aim was to assess the clinical outcomes of the Direct Flow Medical Transcatheter Aortic Valve System (DFM-TAVS), when used in routine clinical practice. METHODS AND RESULTS: This is a prospective, open-label, multicentre, post-market registry of patients treated with DFM-TAVS according to approved commercial indications. Echocardiographic and angiographic data were evaluated by an independent core laboratory and adverse events were adjudicated and classified according to VARC-2 criteria by an independent clinical events committee...
December 10, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27933511/appraisal-of-the-quality-and-contents-of-clinical-practice-guidelines-for-hypertension-management-in-chinese-medicine-a-systematic-review
#8
REVIEW
Ya Yuwen, Xue-Jie Han, Wei-Liang Weng, Xue-Yao Zhao, Yu-Qi Liu, Wei-Qiang Li, Da-Sheng Liu, Yan-Ping Wang, Ai-Ping Lu
OBJECTIVE: To evaluate the quality and consistency of recommendations in the clinical practice guidelines (CPGs) for hypertension in Chinese medicine (CM). METHODS: CM CPGs were identified from 5 electronic databases and hand searches through related handbooks published from January 1990 to December 2013. Three reviewers independently appraised the CPGs based on the Appraisal of Guidelines for Research and Evaluation (AGREE II) instrument, and compared the CPGs' recommendations on CM syndrome pattern classification and treatment...
December 9, 2016: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/27932913/lifewatchgreece-portal-development-architecture-implementation-and-challenges-for-a-biodiversity-research-e-infrastructure
#9
Alexandros Gougousis, Nicolas Bailly
BACKGROUND: Biodiversity data is characterized by its cross-disciplinary character, the extremely broad range of data types and structures, and the plethora of different data sources providing resources for the same piece of information in a heterogeneous way. Since the web inception two decades ago, there are multiple initiatives to connect, aggregate, share, and publish biodiversity data, and to establish data and work flows in order to analyze them. The European program LifeWatch aims at establishing a distributed network of nodes implementing virtual research environment in Europe to facilitate the work of biodiversity researchers and managers...
2016: Biodiversity Data Journal
https://www.readbyqxmd.com/read/27932630/hospital-doctors-understanding-of-use-and-withdrawal-of-the-liverpool-care-pathway-a-qualitative-study-of-practice-based-experiences-during-times-of-change
#10
Sharon Twigger, Sarah J Yardley
BACKGROUND: The Liverpool Care Pathway was used in UK hospitals (late 1990s to July 2014) in an attempt to generate hospice-style high-quality end-of-life care in acute settings. Despite being widely established, there was limited research or contextual evidence regarding this approach or its impact. Growing criticism from the public, media, politicians and healthcare professionals culminated with a critical independent review (July 2013) and subsequent withdrawal of the Liverpool Care Pathway...
December 8, 2016: Palliative Medicine
https://www.readbyqxmd.com/read/27932341/older-patient-considering-treatment-for-advanced-renal-disease-protocol-for-a-scoping-review-of-the-information-available-for-shared-decision-making
#11
Rajesh Raj, Kiran D K Ahuja, Mai Frandsen, Matthew Jose
INTRODUCTION: Older adults constitute the largest group of patients on dialysis in most parts of the world. Management of advanced renal disease in the older adult is complex; treatment outcomes and prognosis can be markedly different from younger patients. Clinical teams caring for such patients are often called on to provide information regarding prognosis and outcomes with treatment-particularly, the comparison between having dialysis treatment versus not having dialysis. These discussions can be difficult for clinicians because they have to contend with incomplete or nascent data regarding prognosis and outcomes in this age group...
December 8, 2016: BMJ Open
https://www.readbyqxmd.com/read/27932265/ottawa-panel-evidence-based-clinical-practice-guidelines-for-structured-physical-activity-in-the-management-of-juvenile-idiopathic-arthritis
#12
REVIEW
Sabrina Cavallo, Lucie Brosseau, Karine Toupin-April, George A Wells, Christine A M Smith, Arlanna G Pugh, Jennifer Stinson, Roanne Thomas, Sara Ahmed, Ciarán M Duffy, Prinon Rahman, Inmaculada C Àlvarez-Gallardo, Laurianne Loew, Gino De Angelis, Debbie Ehrmann Feldman, Annette Majnemer, Isabelle J Gagnon, Désirée Maltais, Marie-Ève Mathieu, Glen P Kenny, Susan Tupper, Kristi Whitney-Mahoney, Sarah Bigford
OBJECTIVE: To create guidelines focused on the use of structured physical activity (PA) in the management of juvenile idiopathic arthritis (JIA). DATA SOURCES: A systematic literature search was conducted using the electronic databases Cochrane Central Register of Controlled Trials, Medline (Ovid), EMBASE (Ovid), and Physiotherapy Evidence Database (PEDro) for all studies related to PA programs for JIA from January 1966 until December 2014, and was updated in May 2015...
December 5, 2016: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/27931167/astronomy-and-calendar-reform-at-the-curia-of-pope-clement-vi-a-new-source
#13
C Philipp E Nothaft
The article introduces a previously unknown fourteenth-century treatise on computus and calendrical astronomy entitled Expositio kalendarii novi, whose author proposed elaborate solutions to the technical flaws inherent in the calendar used by the Roman Church. An analysis of verbal parallels to other contemporary works on the same topic makes it possible to establish that the Expositio was produced in the context of a calendar reform initiative led by Pope Clement VI in 1344/45 and that this anonymous text is probably identical to a 'great and laborious work' on the calendar that the monk Johannes de Termis prepared for the pope around this time...
December 9, 2016: Annals of Science
https://www.readbyqxmd.com/read/27931012/impact-of-thrombophilia-screening-on-venous-thromboembolism-management-practices
#14
Alejandro Garcia-Horton, Michael J Kovacs, Jameel Abdulrehman, Jay E Taylor, Shobha Sharma, Alejandro Lazo-Langner
BACKGROUND: It is unclear whether thrombophilia testing provides any further information on risk of recurrence or guidance in management of patients with a first episode of idiopathic venous thromboembolism (VTE). Furthermore, after the introduction to clinical practice of clinical prediction rules, thrombophilia screening could be less relevant in anticoagulation decision making. We assessed the potential impact of thrombophilia screening on the decision of maintaining anticoagulation beyond the initially planned anticoagulation period in patients with an unprovoked VTE, before and after the introduction of a clinical prediction rule into practice...
December 1, 2016: Thrombosis Research
https://www.readbyqxmd.com/read/27930944/high-throughput-sequencing-in-acute-lymphoblastic-leukemia-follow-up-of-minimal-residual-disease-and-emergence-of-new-clones
#15
Mikaël Salson, Mathieu Giraud, Aurélie Caillault, Nathalie Grardel, Nicolas Duployez, Yann Ferret, Marc Duez, Ryan Herbert, Tatiana Rocher, Shéhérazade Sebda, Sabine Quief, Céline Villenet, Martin Figeac, Claude Preudhomme
Minimal residual disease (MRD) is known to be an independent prognostic factor in patients with acute lymphoblastic leukemia (ALL). High-throughput sequencing (HTS) is currently used in routine practice for the diagnosis and follow-up of patients with hematological neoplasms. In this retrospective study, we examined the role of immunoglobulin/T-cell receptor-based MRD in patients with ALL by HTS analysis of immunoglobulin H and/or T-cell receptor gamma chain loci in bone marrow samples from 11 patients with ALL, at diagnosis and during follow-up...
November 21, 2016: Leukemia Research
https://www.readbyqxmd.com/read/27930790/detection-of-keratoconus-with-a-new-biomechanical-index
#16
Riccardo Vinciguerra, Renato Ambrósio, Ahmed Elsheikh, Cynthia J Roberts, Bernardo Lopes, Emanuela Morenghi, Claudio Azzolini, Paolo Vinciguerra
PURPOSE: To evaluate the ability of a new combined biomechanical index called the Corvis Biomechanical Index (CBI) based on corneal thickness profile and deformation parameters to separate normal from keratoconic patients. METHODS: Six hundred fifty-eight patients (329 eyes in each database) were included in this multicenter retrospective study. Patients from two clinics located on different continents were selected to test the capability of the CBI to separate healthy and keratoconic eyes in more than one ethnic group using the Corvis ST (Oculus Optikgeräte GmbH, Wetzlar, Germany)...
December 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27930752/prevalence-of-body-dysmorphic-disorder-and-surgeon-diagnostic-accuracy-in-facial-plastic-and-oculoplastic-surgery-clinics
#17
Andrew W Joseph, Lisa Ishii, Shannon S Joseph, Jane I Smith, Peiyi Su, Kristin Bater, Patrick Byrne, Kofi Boahene, Ira Papel, Theda Kontis, Raymond Douglas, Christine C Nelson, Masaru Ishii
Importance: Body dysmorphic disorder (BDD) is a relative contraindication for facial plastic surgery, but formal screening is not common in practice. The prevalence of BDD in patients seeking facial plastic surgery is not well documented. Objective: To establish the prevalence of BDD across facial plastic and oculoplastic surgery practice settings, and estimate the ability of surgeons to screen for BDD. Design, Setting, and Participants: This multicenter prospective study recruited a cohort of 597 patients who presented to academic and private facial plastic and oculoplastic surgery practices from March 2015 to February 2016...
December 8, 2016: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/27929671/development-and-initial-psychometrics-for-a-therapist-competence-instrument-for-cbt-for-youth-anxiety
#18
Bryce D McLeod, Michael A Southam-Gerow, Adriana Rodríguez, Alexis M Quinoy, Cassidy C Arnold, Philip C Kendall, John R Weisz
Therapist competence is an important component of treatment integrity. This article reports on the development and initial psychometric assessment of the Cognitive-Behavioral Treatment for Anxiety in Youth Competence Scale (CBAY-C), an observational instrument designed to capture therapist limited-domain competence (i.e., competence in the delivery of core interventions and delivery methods found in a specific psychosocial treatment program) in the delivery of the core practice elements in individual cognitive-behavioral treatment (ICBT) for youth anxiety...
December 8, 2016: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/27929003/certified-randomness-in-quantum-physics
#19
Antonio Acín, Lluis Masanes
The concept of randomness plays an important part in many disciplines. On the one hand, the question of whether random processes exist is fundamental for our understanding of nature. On the other, randomness is a resource for cryptography, algorithms and simulations. Standard methods for generating randomness rely on assumptions about the devices that are often not valid in practice. However, quantum technologies enable new methods for generating certified randomness, based on the violation of Bell inequalities...
December 7, 2016: Nature
https://www.readbyqxmd.com/read/27928699/estimating-the-oncotypedx-score-validation-of-an-inexpensive-estimation-tool
#20
Anne A Eaton, Catherine E Pesce, James O Murphy, Michelle M Stempel, Sujata M Patil, Edi Brogi, Clifford A Hudis, Mahmoud El-Tamer
BACKGROUND: OncotypeDX, a multi-gene expression assay, has been incorporated into clinical practice as a prognostic and predictive tool. However, its use in resource-constrained international healthcare systems is limited. Here we develop and validate a simplified model using clinicopathologic criteria to predict OncotypeDX score. METHODS: Patients with estrogen receptor (ER) and/or progesterone receptor (PR)-positive and HER2-negative invasive ductal carcinoma for whom the OncotypeDX test was successfully performed between 09/2008 and 12/2011 were retrospectively identified...
December 7, 2016: Breast Cancer Research and Treatment
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