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https://www.readbyqxmd.com/read/28643155/mind-wandering-how-do-i-measure-thee-with-probes-let-me-count-the-ways
#1
Yana Weinstein
In the past decade, a new field has formed to investigate the concept of mind-wandering, or task-unrelated thought. The state of mind-wandering is typically contrasted with being on-task, or paying attention to the task at hand, and is related to decrements in performance on cognitive tasks. The most widely used method for collecting mind-wandering data-the probe-caught method-involves stopping participants during a task and asking them where their attention is directed. In this review, 145 studies from 105 articles published between 2005 and 2015 were classified according to the framing and wording of the thought probe and response options...
June 22, 2017: Behavior Research Methods
https://www.readbyqxmd.com/read/28637571/workforce-issues-in-pediatric-surgery
#2
Don K Nakayama
High salaries indicate a demand for pediatric surgeons in excess of the supply, despite only a slight growth in the pediatric-age population and a sharp increase in numbers of trainees. Top-level neonatal intensive care units require 24-hour-7-day pediatric surgical availability, so hospitals are willing to pay surgeons a premium and engage high-priced locum tenens surgeons to fill vacancies in coverage. With increased supply comes an erosion of the numbers of cases performed by trainees and surgeons in practice...
June 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28629328/impact-of-systematic-capacity-building-on-cataract-surgical-service-development-in-25-hospitals
#3
Katherine Judson, Paul Courtright, Thulsiraj Ravilla, Rohit Khanna, Ken Bassett
BACKGROUND: This study measured the effectiveness and cost of a capacity building intervention in 25 eye hospitals in South Asia, East Africa and Latin America over 4 years. The intervention involved eye care non-governmental organizations or high-performing eye hospitals acting as "mentors" to underperforming eye hospitals- "mentees" in 10 countries. Intervention activities included systematic planning and support for training and key equipment purchases as well as hospital-specific mentoring which focused on strengthening leadership, increasing the volume and equity of community outreach, improving surgical quality and volume, strengthening organizational and financial management and streamlining operational processes...
June 19, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28625506/long-term-cost-effectiveness-of-two-glp-1-receptor-agonists-for-the-treatment-of-type-2-diabetes-mellitus-in-the-italian-setting-liraglutide-versus-lixisenatide
#4
Barnaby Hunt, Nana Kragh, Ceilidh C McConnachie, William J Valentine, Maria C Rossi, Roberta Montagnoli
PURPOSE: Maintaining glycemic control is the key treatment target for patients with type 2 diabetes mellitus. In addition, the glucagon-like peptide-1 (GLP-1) receptor agonists may be associated with other favorable treatment characteristics, such as reduction in body weight and reduced risk of hypoglycemia compared with traditional diabetes interventions. The aim of the present analysis was to compare the long-term cost-effectiveness of 2 GLP-1 receptor agonists, liraglutide 1.8 mg and lixisenatide 20 μg (both administered once daily), in the treatment of patients with type 2 diabetes failing to achieve glycemic control with metformin monotherapy in the Italian setting...
June 15, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28623159/epigenetic-biomarkers-and-cardiovascular-disease-circulating-micrornas
#5
David de Gonzalo-Calvo, Eduardo Iglesias-Gutiérrez, Vicenta Llorente-Cortés
MicroRNAs (miRNAs) are a class of small noncoding RNA (20-25 nucleotides) involved in gene regulation. In recent years, miRNAs have emerged as a key epigenetic mechanism in the development and physiology of the cardiovascular system. These molecular species regulate basic functions in virtually all cell types, and are therefore directly associated with the pathophysiology of a large number of cardiovascular diseases. Since their relatively recent discovery in extracellular fluids, miRNAs have been studied as potential biomarkers of disease...
June 13, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28618611/large-scale-structure-of-randomly-jammed-spheres
#6
Atsushi Ikeda, Ludovic Berthier, Giorgio Parisi
We numerically analyze the density field of three-dimensional randomly jammed packings of monodisperse soft frictionless spherical particles, paying special attention to fluctuations occurring at large length scales. We study in detail the two-point static structure factor at low wave vectors in Fourier space. We also analyze the nature of the density field in real space by studying the large-distance behavior of the two-point pair correlation function, of density fluctuations in subsystems of increasing sizes, and of the direct correlation function...
May 2017: Physical Review. E
https://www.readbyqxmd.com/read/28617175/operator-models-for-delivering-municipal-solid-waste-management-services-in-developing-countries-part-a-the-evidence-base
#7
David C Wilson, Jennifer Bangirana Kanjogera, Reka Soós, Cosmin Briciu, Stephen R Smith, Andrew D Whiteman, Sandra Spies, Barbara Oelz
This article presents the evidence base for 'operator models' - that is, how to deliver a sustainable service through the interaction of the 'client', 'revenue collector' and 'operator' functions - for municipal solid waste management in emerging and developing countries. The companion article addresses a selection of locally appropriate operator models. The evidence shows that no 'standard' operator model is effective in all developing countries and circumstances. Each city uses a mix of different operator models; 134 cases showed on average 2...
June 1, 2017: Waste Management & Research
https://www.readbyqxmd.com/read/28613066/balance-billing-by-health-care-providers-assessing-consumer-protections-across-states
#8
Kevin Lucia, Jack Hoadley, Ashley Williams
ISSUE: Privately insured consumers expect that if they pay premiums and use in-network providers, their insurer will cover the cost of medically necessary care beyond their cost-sharing. However, when obtaining care at emergency departments and in-network hospitals, patients treated by an out-of-network provider may receive an unexpected "balance bill" for an amount beyond what the insurer paid. With no explicit federal protections against balance billing, some states have stepped in to protect consumers from this costly and confusing practice...
June 2017: Issue Brief of the Commonwealth Fund
https://www.readbyqxmd.com/read/28604141/cost-effectiveness-of-subdermal-implantable-buprenorphine-versus-sublingual-buprenorphine-to-treat-opioid-use-disorder
#9
John A Carter, Ryan Dammerman, Michael Frost
AIMS: Subdermal implantable buprenorphine (BSI) was recently approved to treat opioid use disorder (OUD) in clinically-stable adults. In the pivotal clinical trial, BSI was associated with a higher proportion of completely-abstinent patients (85.7% vs 71.9%; P = 0.03) versus sublingual buprenorphine (SL-BPN). Elsewhere, relapse to illicit drug use is associated with diminished treatment outcomes and increased costs. Herein, we evaluated the cost-effectiveness of BSI versus SL-BPN from a US societal perspective...
June 10, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28599810/comparative-cost-benefit-analysis-of-tele-homecare-for-community-dwelling-elderly-in-japan-non-government-versus-government-supported-funding-models
#10
Miki Akiyama, Chon Abraham
OBJECTIVE: Tele-homecare is gaining prominence as a viable care alternative, as evidenced by the increase in financial support from international governments to fund initiatives in their respective countries. The primary reason for the funding is to support efforts to reduce lags and increase capacity in access to care as well as to promote preventive measures that can avert costly emergent issues from arising. These efforts are especially important to super-aged and aging societies such as in Japan, many European countries, and the United States (US)...
August 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28590130/paying-the-price-of-desolvation-in-solvent-exposed-protein-pockets-impact-of-distal-solubilizing-groups-on-affinity-and-binding-thermodynamics-in-a-series-of-thermolysin-inhibitors
#11
Jonathan Cramer, Stefan G Krimmer, Andreas Heine, Gerhard Klebe
In medicinal-chemistry lead optimization programs open, solvent-exposed protein pockets are often disregarded as prospective binding sites. Due to the proximity of the bulk solvent, many researchers are instead enticed to attach charged and polar groups to a respective position of an inhibitor scaffold in order to improve solubility and pharmacokinetic properties of a lead candidate. It is rarely considered that solvent effects from the organization of water molecules in the first hydration shell of a protein-ligand complex can take significant impact on the thermodynamics of binding...
June 7, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28583973/solving-disparities-through-payment-and-delivery-system-reform-a-program-to-achieve-health-equity
#12
Rachel H DeMeester, Lucy J Xu, Robert S Nocon, Scott C Cook, Andrea M Ducas, Marshall H Chin
Payment systems generally do not directly encourage or support the reduction of health disparities. In 2013 the Finding Answers: Solving Disparities through Payment and Delivery System Reform program of the Robert Wood Johnson Foundation sought to understand how alternative payment models might intentionally incorporate a disparities-reduction component to promote health equity. A qualitative analysis of forty proposals to the program revealed that applicants generally did not link payment reform tightly to disparities reduction...
June 1, 2017: Health Affairs
https://www.readbyqxmd.com/read/28583120/-until-people-start-dying-in-droves-no-actions-will-be-taken-perception-and-experience-of-hiv-preventive-measures-among-people-who-inject-drugs-in-northwestern-russia
#13
Peter Meylakhs, Aadne Aasland, Arne Grønningsæter
BACKGROUND: The HIV epidemic among people who inject drugs (PWID) in Russia continues to spread. This exploratory study examines how HIV-prevention measures are perceived and experienced by PWID in the northwestern region of Russia. METHODS: Purposive sampling was used to obtain a variety of cases that could reflect possible differences in perception and experience of HIV-prevention efforts. We conducted 22 semi-structured interviews with PWID residing in the Arkhangelsk and St...
June 5, 2017: Harm Reduction Journal
https://www.readbyqxmd.com/read/28580909/the-dynamo-package-for-tomography-and-subtomogram-averaging-components-for-matlab-gpu-computing-and-ec2-amazon-web-services
#14
Daniel Castaño-Díez
Dynamo is a package for the processing of tomographic data. As a tool for subtomogram averaging, it includes different alignment and classification strategies. Furthermore, its data-management module allows experiments to be organized in groups of tomograms, while offering specialized three-dimensional tomographic browsers that facilitate visualization, location of regions of interest, modelling and particle extraction in complex geometries. Here, a technical description of the package is presented, focusing on its diverse strategies for optimizing computing performance...
June 1, 2017: Acta Crystallographica. Section D, Structural Biology
https://www.readbyqxmd.com/read/28545377/phenolic-compounds-from-edible-algae-bioactivity-and-health-benefits
#15
Lidia Montero, Andrea Del Pilar Sánchez-Camargo, Elena Ibáñez, Bienvenida Gilbert-López
Algae have been consumed for many years in Asian countries; at present, its consumption around the world either as food ingredient or directly as food commodity has increased considerably mainly due to the Asian influence and its cuisine, but also because the growing interest on the beneficial health effects of algae. Although several biological activities have been attributed to different algae compounds such as pigments, lipids, polysaccharides, fiber, proteins or vitamins, in the present review we will highlight the different phenolic compounds present on seaweeds and their important role in the functional and health effects, paying special attention to the antioxidant, antiproliferative, anti-obesity and antidiabetic activities...
May 23, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28544896/exploring-mechanisms-of-change-in-cognitive-therapy-and-interpersonal-psychotherapy-for-adult-depression
#16
Lotte H J M Lemmens, Francisca Galindo-Garre, Arnoud Arntz, Frenk Peeters, Steven D Hollon, Robert J DeRubeis, Marcus J H Huibers
The present study explored the temporal relationships between change in five candidate causal mechanisms and change in depressive symptoms in a randomized comparison of individual Cognitive Therapy (CT) and Interpersonal Psychotherapy (IPT) for adult depression. Furthermore, hypotheses concerning the mediation of change in these treatments were tested. Patients were 151 depressed adult outpatients treated with either CT (n = 76) or IPT (n = 75). Depression severity was assessed with the BDI-II. Candidate mediators included both therapy-specific as well as common factors...
May 8, 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28544860/behavioral-processes-in-long-lag-intervention-studies
#17
Dale T Miller, Jennifer E Dannals, Julian J Zlatev
We argue that psychologists who conduct experiments with long lags between the manipulation and the outcome measure should pay more attention to behavioral processes that intervene between the manipulation and the outcome measure. Neglect of such processes, we contend, stems from psychology's long tradition of short-lag lab experiments where there is little scope for intervening behavioral processes. Studying process in the lab invariably involves studying psychological processes, but in long-lag field experiments it is important to study causally relevant behavioral processes as well as psychological ones...
May 2017: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/28544070/the-importance-of-assessing-out-of-pocket-payments-when-the-financing-of-antiretroviral-therapy-is-transitioned-to-domestic-funding-findings-from-vietnam
#18
Benjamin Johns, Le Bao Chau, Kieu Huu Hanh, Nguyen Thuy Huong, Hoa Mai Do, Anh Thuy Duong, Long Hoang Nguyen
OBJECTIVE: To assess out-of-pocket payments and catastrophic health expenditures among antiretroviral therapy (ART) patients in Vietnam, and to model catastrophic payments under different copayment scenarios when the primary financing of ART changes to social health insurance. METHODS: Cross-sectional facility-based survey of 843 patients at 42 health facilities representative of 87% of ART patients in 2015. RESULTS: Because of donor and government funding, no payments were made for antiretroviral drugs...
May 19, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28541931/the-role-of-constructed-wetlands-for-biomass-production-within-the-water-soil-waste-nexus
#19
C T Avellan, R Ardakanian, P Gremillion
The use of constructed wetlands for water pollution control has a long standing tradition in urban, peri-urban, rural, agricultural and mining environments. The capacity of wetland plants to take up nutrients and to filter organic matter has been widely discussed and presented in diverse fora and published in hundreds of articles. In an ever increasingly complex global world, constructed wetlands not only play a role in providing safe sanitation in decentralized settings, shelter for biodiversity, and cleansing of polluted sites, in addition, they produce biomass that can be harvested and used for the production of fodder and fuel...
May 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28540162/effect-of-brand-and-advertising-medium-on-demand-for-e-cigarettes-evidence-from-an-experimental-auction
#20
Matthew C Rousu, Richard O'Connor, Jay Corrigan
Print and television advertisements for e-cigarettes are currently legal in the United States. Given that e-cigarettes are a lower-risk alternative to cigarettes, these ads could have a positive public health impact if they motivate smokers to switch to e-cigarettes. However, the public health impact of e-cigarette ads could be negative if ads increase demand for both e-cigarettes and cigarettes. We use experimental auctions -in which participants bid in real auctions and winners pay for the items they purchase - to study the effect of print and TV e-cigarettes ads on demand for the brand from the ad, for another e-cigarettes brand, and for cigarettes...
September 2017: Preventive Medicine Reports
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