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Lissa Davis, Jooyeoun Jung, Ann Colonna, Aimee Hasenbeck, Virginia Gouw, Yanyun Zhao
Blueberry pomace (BP) and cranberry pomace (CP) are good sources of dietary fiber and phenolics. This study aimed to develop berry fruit pomace (FP)-fortified specialty mustard with elevated bioactive compounds and ascertain consumer acceptance of a new product. Wet BP and CP were ground and incorporated into Dijon-style mustard at concentrations of 15%, 20%, and 25% (w/w). Total dietary fiber (TDF), total phenolic content (TPC), and radical scavenging activity (RSA) were evaluated for samples obtained from both chemical extraction (CE) and simulated gastrointestinal digestion (SGD)...
June 15, 2018: Journal of Food Science
Thomas Mellette, Kathryn Yerxa, Mona Therrien, Mary Ellen Camire
Adolescents and young adults in the United States do not consume recommended amounts of whole grains. University dining services have opportunities to inform students about whole grains and to offer foods containing blends of whole grains with refined flour to increase daily consumption of these healthful foods. An online survey of university students ( n = 100) found that 70% of respondents did not know the proportion of servings of whole grains that should be eaten daily. Mini blueberry muffins containing 50, 75, and 100% white whole wheat flour were served to 50 undergraduate students who rated their liking of the muffins using a nine-point hedonic scale...
June 13, 2018: Foods (Basel, Switzerland)
Michaela Zeiner, Iva Juranović Cindrić
Fruits and vegetables are considered a beneficial contribution to the human diet. Especially, berries contain a great deal of bioactive compounds, such as anthocyanins, organic acids, tannins, phenols, and antioxidants. Apart from organic substances, inorganic nutrients are also present in fruits. Some metals and metalloids are essential for humans, whilst others may exhibit harmful effects. Wild grown berries, collected in so-called unpolluted areas, are considered to be free of any potentially toxic ingredients...
June 8, 2018: Toxics
Aaron Walworth, Guo-Qing Song
Expression of blueberry cold-regulated genes (VcCORs) could play a role in the variable cold hardiness of blueberry tissues. In this study, transcriptome comparisons were conducted to reveal expression of VcCORs in non-acclimated leaves, flower buds, and flowers of both non-transgenic and transgenic blueberries containing an overexpressed blueberry DWARF AND DELAYED FLOWERING gene ( VcDDF1 ) as well as in fully chilled flower buds of non-transgenic blueberry. In non-transgenic blueberries, 57.5% of VcCOR genes showed differential expression in at least one of the three pairwise comparisons between non-acclimated leaves, flower buds, and flowers, and six out of nine dehydration-responsive element-binding factors showed differential expression...
May 23, 2018: International Journal of Molecular Sciences
Adrian R Whyte, Nancy Cheng, Emilie Fromentin, Claire M Williams
Previous research has shown beneficial effects of polyphenol-rich diets in ameliorating cognitive decline in aging adults. Here, using a randomized, double blinded, placebo-controlled chronic intervention, we investigated the effect of two proprietary blueberry formulations on cognitive performance in older adults; a whole wild blueberry powder at 500 mg (WBP500) and 1000 mg (WBP1000) and a purified extract at 100 mg (WBE111). One hundred and twenty-two older adults (65⁻80 years) were randomly allocated to a 6-month, daily regimen of either placebo or one of the three interventions...
May 23, 2018: Nutrients
Amit Kumar Singh, Anupam Bishayee, Abhay K Pandey
Cancer initiation and progression are the result of genetic and/or epigenetic alterations. Acetylation-mediated histone/non-histone protein modification plays an important role in the epigenetic regulation of gene expression. Histone modification is controlled by the balance between histone acetyltransferase and (HAT) and histone deacetylase (HDAC) enzymes. Imbalance between the activities of these two enzymes is associated with various forms of cancer. Histone deacetylase inhibitors (HDACi) regulate the activity of HDACs and are being used in cancer treatment either alone or in combination with other chemotherapeutic drugs/radiotherapy...
June 6, 2018: Nutrients
Masao Yamasaki, Kensaku Hamada, Kento Fujii, Kazuo Nishiyama, Yumi Yamasaki, Hiroyuki Tari, Kaori Araki, Teruaki Arakawa
Blueberry ( Vaccinium ashei ) leaf has recently attracted attention as an anti-obesity food component. In this study, we examined the effects of blueberry leaf extract (BLEx) on insulin signaling in C2C12 differentiated myoblasts. The results showed that BLEx promotes the intracellular uptake of 2-[ N -(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-D-glucose (2- N BDG) and phosphorylation of Akt under insulin stimulation. In addition, pretreatment with BLEx ameliorated TNF-α-nduced insulin resistance with regard to 2-NBDG uptake and Akt phosphorylation...
July 2018: Biochemistry and Biophysics Reports
Guillermo Cásedas, Elena González-Burgos, Carine Smith, Víctor López, María Pilar Gómez-Serranillos
Blueberry and cranberry are fruits with high polyphenol content, particularly anthocyanins. As cyanidin derivatives have been identified as one of the most representative polyphenols in berry juices, cyanidin has been designated for a better comparison and understanding of the potential neuroprotection of juices obtained from two Vaccinium species. Neuroblastoma SH-SY5Y cells were previously treated with different concentrations of lyophilized blueberry juice, cranberry juice or cyanidin for 24 h and oxidative stress was then generated with hydrogen peroxide (100 μM) for 30 min...
May 31, 2018: Food and Chemical Toxicology
Erin D Lewis, Zhihong Ren, Jason DeFuria, Martin S Obin, Simin N Meydani, Dayong Wu
Blueberry, rich in antioxidant and anti-inflammatory phytochemicals, has been demonstrated to lower inflammatory status in adipose induced by high-fat diet (HFD) and obesity. The effect of blueberry on systemic immune functions has not been examined. C57BL/6 mice were randomised to one of three diets - low-fat diet (LFD), HFD and HFD plus 4 % (w/w) blueberry (HFD+B) - for 8 or 12 weeks. Ex vivo T-cell mitogens (concanavalin A (Con A); phytohaemagglutinin), T-cell antibody (anti-CD3; anti-CD3/CD28)-stimulated T-cell proliferation and cytokine production were assessed...
June 2018: British Journal of Nutrition
Eric F LoPresti, Moria Robinson, Billy A Krimmel, Grace K Charles
In the coast range of California, the fruit of several manzanita (Arctostaphylos) species, including A. viscida, A. glandulosa, and A. hooveri, are covered in glandular-sticky hairs. The blueberry-sized fruit remain viscid after ripening, and if you walk through dense manzanita patches during the late spring and summer you are bound to end up with globs of fruit hanging loosely from your shirt and pants. While picking the fruit off your clothes, you may also notice that many of the fruit have dead insects firmly stuck in the glue-like exudates secreted by their dense glandular trichomes (Figure 1)...
May 30, 2018: Ecology
Baoying Zhao, Xinxin Shao, Bosheng Zhao, Zuoqing Yuan, Jianyong Zhang
Perfluorooctane sulfonate (PFOS) which has been distributed worldwide is a persistent organic contaminant. Blueberry anthocyanins (ANT) are phytonutrients with antioxidant activities. The influence of different PFOS and ANT concentrations on the behavioral activities, regeneration of planarians (Dugesia japonica), and the expression levels and contents of Djnad6 and Djcox1 genes has been investigated. PFOS treatments affected the gene expression levels, induced a decrease in the planarians' locomotor velocity, and increased the time required for the regeneration of the transverse amputated fragments in a time- and dose-dependent manner...
May 25, 2018: Environmental Science and Pollution Research International
Ning Zhu, Ning Yu, Yue Zhu, Yulong Wei, Yanan Hou, Haiping Zhang, Ai-Dong Sun
Blueberry juice is a healthy and nutritious food that has become increasingly popular worldwide. However, little is known about the microbial groups of this juice that can cause its spoilage. This study aimed to identify the main spoilage microorganisms in blueberry juice and explore whether a microchip pulsed electric field (MPEF) can effectively inactivate them. We performed polymerase chain reaction (PCR) amplification, as well as 16S rDNA, 18S rDNA, internal transcribed spacer (ITS), and 26S rDNA gene sequence analyses...
May 25, 2018: Scientific Reports
María Gretel Michel-Barba, Hugo Espinosa-Andrews, Rudy Antonio García-Reyes, Yves Desjardins, Marisela González-Ávila
The blueberry is recognised as a source of phenolic compounds that have beneficial effects on human health; however, they possess low bioavailability and can be degraded by gastrointestinal conditions. Encapsulation has been widely used to mitigate these disadvantages; Gum Arabic (GA) and Corn Syrup Solids (CSS) are common carriers used in this technique. The aim of this study was to evaluate the effect of Blueberry Extract (BE), carriers and their mixtures on the kinetic growth and maximal growth rate of probiotics and pathogenic bacteria...
May 24, 2018: International Journal of Food Sciences and Nutrition
Clemens Reimann, Karl Fabian, Belinda Flem, Malin Andersson, Peter Filzmoser, Peter Englmaier
Geochemical element separation is studied in 14 different sample media collected at 41 sites along an approximately 100-km long transect north of Oslo. At each site, soil C and O horizons and 12 plant materials (birch/spruce/cowberry/blueberry leaves/needles and twigs, horsetail, braken fern, pine bark and terrestrial moss) were sampled. The observed concentrations of 29 elements (K, Ca, P, Mg, Mn, S, Fe, Zn, Na, B, Cu, Mo, Co, Al, Ba, Rb, Sr, Ti, Ni, Pb, Cs, Cd, Ce, Sn, La, Tl, Y, Hg, Ag) were used to investigate soil-plant relations, and to evaluate the element differentiation between different plants, or between foliage and twigs of the same plant...
May 17, 2018: Science of the Total Environment
Hai-Qiang Li, Long Tan, Hong-Peng Yang, Wei Pang, Tong Xu, Yu-Gang Jiang
OBJECTIVE: To examine protein changes in the hippocampus of APP/PS1 transgenic mice after blueberry extracts (BB) intervention. METHODS: Eight APP/PS1 transgenic mice were randomly assigned to Alzheimer's disease (AD)+BB group (n=4) and AD+control group (n=4). After a 16-week treatment, 2-DE and MALDI-TOF-MS were used to compare the proteomic profiles of the hippocampus in the two groups and Western blot was used to confirm the important differentially expressed proteins...
May 21, 2018: Nutritional Neuroscience
Swen Langer, Aileen Kennel, John K Lodge
The consumption of berries has been linked to decreased risk of degenerative disease. Berries are regularly processed into juices. It is largely unknown how the juicing process affects the bioavailability of metabolites. As metabolomics has shown to be a valuable nutritional tool to study global metabolite differences, the aim of this study was to investigate the effect of juicing on the relative appearance of blueberry metabolites in humans using metabolomics. Nine healthy subjects consumed 250 g of fresh blueberries either as the whole fruit or after juicing, and provided blood and urine samples before and 2 h after intake in a cross-over design...
June 2018: British Journal of Nutrition
Boris Nemzer, Luis Vargas, Xiaoyan Xia, Marsha Sintara, Hao Feng
The effects of hot-air drying (AD), freeze drying (FD) and Refractance Window drying (RWD) on the retention of anthocyanins, phenolics, flavonoids, vitamin C and B, and antioxidant capacity (ORAC) in blueberries, tart cherries, strawberries, and cranberries, as well as organic acids and proanthocyanins in cranberries and chlorogenic acid and catchins in blueberries were evaluated. Changes in color, glass transition, specific heat, and surface morphology of the dried fruits were also evaluated. The quality retention in the dried fruits was found to be product and drying method specific...
October 1, 2018: Food Chemistry
Madelief Mollers, Ingeborg L A Boxman, Harry Vennema, Ife A Slegers-Fitz-James, Diederik Brandwagt, Ingrid H Friesema, Jenny S Batstra, Margreet J M Te Wierik
This study describes an outbreak investigation of 14 hepatitis A cases in the Netherlands. The hepatitis A virus (HAV) genotype IB sequences in cases were highly similar (459/460 nt). The origin of strains could be narrowed to Bulgaria based on information from EPIS-FWD. As an association with consumption of soft fruit was suspected, a case-control study was initiated using a questionnaire and a list of pictures of soft fruit available at the supermarket chain involved. Twelve out of 13 cases consumed a specific frozen raspberry/blueberry product shown on the list (OR 46...
May 4, 2018: Food and Environmental Virology
Yang Lin, Yuehua Wang, Bin Li, Hui Tan, Dongnan Li, Li Li, Xuan Liu, Jichen Han, Xianjun Meng
Blueberry (Vaccinium, family Ericaceae) is well known for its strong antioxidant properties and abundant active ingredients including anthocyanins, flavonols, and proanthocyanidins. In this study, variations in anthocyanin and phenolic compounds content in Bluecrop and Northblue blueberry cultivar fruits were studied, and comparative transcriptome analysis was performed to analyze differences in the molecular mechanisms of anthocyanin biosynthesis. A total of 13 799 unique genes were identified by differential expression analysis, and further subjected to GO classification and pathway enrichment...
April 26, 2018: Plant Physiology and Biochemistry: PPB
Cláudia Leites Luchese, Jone Uranga, Jordana Corralo Spada, Isabel Cristina Tessaro, Koro de la Caba
Blueberry waste from juice processing was valorised to develop starch films by compression moulding. The compression process resulted in hydrophobic films with water contact angles even higher than 100° for the films prepared with the highest blueberry waste content. Additionally, the film solubility was reduced by the incorporation of blueberry waste, regardless of the solution pH. These films also exhibited good barrier properties against UV light due to the aromatic compounds present in the blueberry waste...
May 1, 2018: International Journal of Biological Macromolecules
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