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https://www.readbyqxmd.com/read/29153729/ambient-air-pollution-and-the-risk-of%C3%A2-pregnancy-loss-a-prospective-cohort-study
#1
Sandie Ha, Rajeshwari Sundaram, Germaine M Buck Louis, Carrie Nobles, Indulaxmi Seeni, Seth Sherman, Pauline Mendola
OBJECTIVE: To estimate the association of pregnancy loss with common air pollutant exposure. Ambient air pollution exposure has been linked to adverse pregnancy outcomes, but few studies have investigated its relationship with pregnancy loss. DESIGN: Prospective cohort study. SETTING: Not applicable. PATIENT(S): A total of 343 singleton pregnancies in a multisite prospective cohort study with detailed protocols for ovulation and pregnancy testing...
November 14, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/29137553/relationship-between-pregnancy-complications-and-psychiatric-disorders-a-population-based-study-with-a-matched-control-group
#2
Christina D Kang-Yi, Sara L Kornfield, C Neill Epperson, David S Mandell
OBJECTIVES: This study sought to identify whether pregnancy complications differ between women with and without a psychiatric disorder diagnosis prior to pregnancy. METHODS: Women who gave birth between 2007 and 2009 in Pennsylvania and were enrolled in Medicaid from one year prior to their pregnancy until their delivery were included (N=9,930); those with psychiatric disorders were compared with a matched control group (N=4,965 for each). Logistic regression analysis estimated the odds of having a pregnancy complication among those with a psychiatric diagnosis prior to pregnancy, adjusting for demographic characteristics and chronic general medical conditions...
November 15, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/29121445/viraemia-before-during-and-after-pregnancy-in-hiv-infected-women-on-antiretroviral-therapy-in-rural-kwazulu-natal-south-africa-2010-2015
#3
Terusha Chetty, Marie-Louise Newell, Claire Thorne, Anna Coutsoudis
OBJECTIVES: Pregnancy and postpartum viral load suppression is critical to prevent mother-to-child HIV transmission and ensure maternal health. We measured viraemia risk before, during and after pregnancy in HIV-infected women. METHODS: Between 2010 and 2015, 1425 HIV-infected pregnant women on lifelong antiretroviral therapy (ART) for at least six months pre-pregnancy were enrolled in a cohort study in rural KwaZulu-Natal, South Africa. Odds ratios were estimated in multilevel logistic regression, with pregnancy period time varying...
November 9, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29120703/maternal-obesity-gestational-weight-gain-and-asthma-in-offspring
#4
Kristen J Polinski, Jihong Liu, Nansi S Boghossian, Alexander C McLain
INTRODUCTION: Obesity is common among women of childbearing age; intrauterine exposure to maternal obesity or gestational weight gain may influence the development of asthma in early childhood. We examined the relationships of maternal obesity and gestational weight gain with asthma in offspring. METHODS: We used data from the Early Childhood Longitudinal Study-Birth Cohort, which has a nationally representative sample of children followed from birth in 2001 through age 4 (n = 6,450)...
November 9, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/29116720/the-croatian-model-of-integrative-prospective-management-of-epilepsy-and-pregnancy
#5
Snježana Miškov, Romana Gjergja Juraški, Ivan Mikula, Silvio Bašić, Marija Bošnjak Pašić, Vesna Košec, Zlatko Sabol, Aleksandra Fučić, Tomislav Sajko, Vanja Bašić Kes
Epilepsy is the most common neurological complication in pregnancy. Women with epilepsy have a higher risk of complications in pregnancy. In Croatia, women with epilepsy are treated by neurologists at tertiary centers according to the place of residence. We prospectively followed-up pregnancies in women with epilepsy and healthy controls, and analyzed the factors responsible for their delivery outcomes and development of their babies. Healthy pregnant women had a higher level of education and economic status, but pregnant women with epilepsy took folic acid in a higher proportion than controls, possibly due to timely preconception counseling...
December 2016: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29115118/adenomyosis-fertility-and-obstetric-outcome-a-comprehensive-literature-review
#6
Laura Buggio, Ermelinda Monti, Umberto Gattei, Dhohua Dridi, Paolo Vercellini
Adenomyosis is a benign condition characterized by the presence of endometrial glands and stroma deep within the myometrium. In recent years, the potential negative impact of adenomyosis on in vitro fertilization clinical outcomes has gained momentum, as well as, the possible link of this condition with obstetrical complications. The aim of this narrative review is to elucidate the possible association between uterine adenomyosis, infertility, and poor obstetrical outcomes. Several theories have been proposed to clarify the potential harmful impact of adenomyosis on fertility, such as a functional and structural defect of both the eutopic endometrium and the inner myometrium, an impairment of the uterine system of sperm transport, the presence of uterine dysperistalsis and of high levels of free radicals in the uterine milieu of women with the disease...
November 7, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/29102040/preconceptional-antithyroid-peroxidase-antibodies-but-not-thyroid-stimulating-hormone-are-associated-with-decreased-live-birth-rates-in-infertile-women
#7
Aimee Seungdamrong, Anne Z Steiner, Clarisa R Gracia, Richard S Legro, Michael P Diamond, Christos Coutifaris, William D Schlaff, Peter Casson, Gregory M Christman, Randal D Robinson, Hao Huang, Ruben Alvero, Karl R Hansen, Susan Jin, Esther Eisenberg, Heping Zhang, Nanette Santoro
OBJECTIVE: To study whether preconceptual thyroid-stimulating hormone (TSH) and antithyroid peroxidase (TPO) antibodies are associated with poor reproductive outcomes in infertile women. DESIGN: Secondary analysis of data from two multicenter, randomized, controlled trials conducted by the Reproductive Medicine Network of the Eunice Kennedy Shriver National Institute of Child Health and Human Development. Multivariable logistic regression analyses were performed to assess the association between preconceptual TSH levels and anti-TPO antibodies...
October 25, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/29099558/antidepressant-exposure-during-pregnancy-and-risk-of-autism-in-the-offspring-2-do-the-new-studies-add-anything-new
#8
Chittaranjan Andrade
BACKGROUND: During the past year, at least 5 new studies, all observational in design, examined the risk of autism spectrum disorder (ASD) in children exposed to antidepressant medication in utero. These studies had not found inclusion in the many systematic reviews and meta-analyses that had also been published in the past year. METHODS: Noteworthy methods and findings of the new studies are summarized. One of these studies is examined in detail to help the reader understand methodological and conceptual issues that are critical in the field...
September 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29096774/thinking-across-generations-unique-contributions-of-maternal-early-life-and-prenatal-stress-to-infant-physiology
#9
Sarah A O Gray, Christopher W Jones, Katherine P Theall, Erin Glackin, Stacy S Drury
OBJECTIVE: Respiratory sinus arrhythmia (RSA) is a parasympathetic-mediated biomarker of self-regulation linked to lifespan mental and physical health outcomes. Intergenerational impacts of mothers' exposure to prenatal stress have been demonstrated, but evidence for biological embedding of maternal preconception stress, including adverse childhood experiences (ACEs), on infant RSA is lacking. We examine the independent effects of maternal ACEs and prenatal stress on infant RSA, seeking to broaden the understanding of the earliest origins of mental and physical health risk...
November 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/29096317/maternal-and-paternal-serum-concentrations-of-persistent-organic-pollutants-and-the-secondary-sex-ratio-a-population-based-preconception-cohort-study
#10
Jisuk Bae, Sungduk Kim, Dana Boyd Barr, Germaine M Buck Louis
Recent declines in the secondary sex ratio (SSR), defined as the ratio of males to females at birth, in some industrialized countries may be attributed to exposure to environmental toxicants such as persistent organic pollutants (POPs). This study aimed to evaluate the association of couples' preconception exposure to POPs with the SSR. The study cohort comprised 235 couples who were enrolled in the Longitudinal Investigation of Fertility and the Environment (LIFE) Study between 2005 and 2009 prior to conception and prospectively followed through delivery of a singleton birth...
October 30, 2017: Environmental Research
https://www.readbyqxmd.com/read/29096279/preconception-lifestyle-changes-in-women-with-planned-pregnancies
#11
Joline Goossens, Dimitri Beeckman, Ann Van Hecke, Ilse Delbaere, Sofie Verhaeghe
OBJECTIVES: (1) to study preconception lifestyle changes and associated factors in women with planned pregnancies; (2) to assess the prevalence of risk factors for adverse pregnancy outcomes in women not reporting any preconception lifestyle changes; and (3) to explore the need for and use of preconception-related advice. DESIGN: secondary data analysis of a cross-sectional study about pregnancy planning. SETTING: six Flemish Hospitals (Belgium)...
October 24, 2017: Midwifery
https://www.readbyqxmd.com/read/29094755/unplanned-pregnancies-in-new-zealand
#12
Bryndl E Hohmann-Marriott
BACKGROUND: Unplanned pregnancies can bring risk. It is important to have an accurate count of unplanned pregnancies, but to date there is no precise number for New Zealand or Australia. AIMS: This analysis estimates the number and proportion of pregnancies in New Zealand that are unplanned. MATERIALS AND METHODS: Estimates were generated using information about unplanned births from the Growing Up in New Zealand study, combined with data on the number of births and abortions from Statistics New Zealand and estimates of miscarriages...
November 2, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29089177/trajectories-of-maternal-leisure-time-physical-activity-and-sedentary-behavior-during-adolescence-to-young-adulthood-and-offspring-birthweight
#13
Sylvia E Badon, Alyson J Littman, Kwun Chuen Gary Chan, Michelle A Williams, Daniel A Enquobahrie
PURPOSE: The objectives of the study were to determine the extent to which trajectories of maternal preconception leisure-time physical activity (LTPA) and leisure-time sedentary behavior (LTSB) during adolescence and young adulthood are associated with offspring birth weight (BW) and to test if these associations differ by offspring sex or maternal pre-pregnancy overweight-obese status. METHODS: Participants with one or more birth (n = 1408) were identified from the National Longitudinal Study of Adolescent to Adult Health...
October 13, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/29080126/perinatal-periods-of-risk-analysis-disentangling-race-and-socioeconomic-status-to-inform-a-black-infant-mortality-community-action-initiative
#14
Catherine L Kothari, Camryn Romph, Terra Bautista, Debra Lenz
Objectives The goal of this study is to use Perinatal Periods of Risk (PPOR) analysis to differentiate broad areas of risk (Maternal-Health/Prematurity, Maternal Care, Newborn Care, and Infant Health) associated with being Black from those associated with being poor. Methods Phase I PPOR compared two target populations (Black women/infants and poor women/infants) against a gold standard reference group (White, non-Hispanic women, aged 20+ years with 13+ years of education), then against each other. Phase II PPOR further partitioned excess risk into (1) Very-low-birthweight-risk and (2) Birthweight-specific-mortality-risk and identified individual-level risk factors...
October 27, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29073129/receipt-of-selected-preventive-health-services-for-women-and-men-of-reproductive-age-united-states-2011-2013
#15
Karen Pazol, Cheryl L Robbins, Lindsey I Black, Katherine A Ahrens, Kimberly Daniels, Anjani Chandra, Anjel Vahratian, Lorrie E Gavin
PROBLEM/CONDITION: Receipt of key preventive health services among women and men of reproductive age (i.e., 15-44 years) can help them achieve their desired number and spacing of healthy children and improve their overall health. The 2014 publication Providing Quality Family Planning Services: Recommendations of CDC and the U.S. Office of Population Affairs (QFP) establishes standards for providing a core set of preventive services to promote these goals. These services include contraceptive care for persons seeking to prevent or delay pregnancy, pregnancy testing and counseling, basic infertility services for those seeking to achieve pregnancy, sexually transmitted disease (STD) services, and other preconception care and related preventive health services...
October 27, 2017: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/29051776/fontan-circulation-and-implications-for-future-reproduction
#16
REVIEW
Niharika Mehta, Srilakshmi Mitta
This article summarizes and critiques four recent publications looking at preconception counseling, pregnancy outcomes, and cardiac complications in women with history of Fontan circulation. The Fontan procedure is a palliative strategy for single-ventricle type congenital heart disease and involves passive flow of venous return into the pulmonary circulation, bypassing the ventricles. Pregnancy in these patients is not without risk and preconception counseling and contraception practices vary widely. High rates of miscarriage, prematurity, and small-for-gestational-age babies are reported...
September 2017: Obstetric Medicine
https://www.readbyqxmd.com/read/29045765/oral-anti-diabetic-agents-for-women-with-established-diabetes-impaired-glucose-tolerance-or-previous-gestational-diabetes-planning-pregnancy-or-pregnant-women-with-pre-existing-diabetes
#17
REVIEW
Joanna Tieu, Suzette Coat, William Hague, Philippa Middleton, Emily Shepherd
BACKGROUND: While most guidance recommends the use of insulin in women whose pregnancies are affected by pre-existing diabetes, oral anti-diabetic agents may be more acceptable to women. The effects of these oral anti-diabetic agents on maternal and infant health outcomes need to be established in pregnant women with pre-existing diabetes or impaired glucose tolerance, as well as in women with previous gestational diabetes mellitus preconceptionally or during a subsequent pregnancy. This review is an update of a review that was first published in 2010...
October 18, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29045283/timing-of-initiation-of-antiretroviral-therapy-and-risk-of-preterm-birth-in-studies-of-hiv-infected-pregnant-women-the-role-of-selection-bias
#18
Marie C D Stoner, Stephen R Cole, Joan Price, Jennifer Winston, Jeff S A Stringer
BACKGROUND: Women who initiate antiretroviral therapy (ART) during pregnancy are reported to have lower risk of preterm birth compared to those who enter pregnancy care already receiving ART. We hypothesize this association can be largely attributed to selection bias. METHODS: We simulated a cohort of 1000 preconceptional, HIV-infected women, where half were randomly allocated to receive immediate ART and half to delay ART until their presentation for pregnancy care...
October 16, 2017: Epidemiology
https://www.readbyqxmd.com/read/29037176/the-association-between-high-birth-weight-and-the-risks-of-childhood-cns-tumors-and-leukemia-an-analysis-of-a-us-case-control-study-in-an-epidemiological-database
#19
Long Thanh Tran, Hang Thi Minh Lai, Chihaya Koriyama, Futoshi Uwatoko, Suminori Akiba
BACKGROUND: High birth weight (BW), 4000 g or larger, is an established risk factor for childhood leukemia. However, its association with central nervous system (CNS) tumor risk is yet unclear. The present study examined it, analyzing data obtained from a case-control study conducted among three states from the US. The association with childhood leukemia risk was also further examined. METHODS: In this study, a data set provided by the Comprehensive Epidemiologic Data Resource was analyzed with an official permission...
October 16, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28994903/antidepressant-exposure-during-pregnancy-and-risk-of-autism-in-the-offspring-1-meta-review-of-meta-analyses
#20
Chittaranjan Andrade
There are no randomized controlled trials of antidepressant drugs to treat depression, or to prevent relapse into depression, during pregnancy; therefore, the safety of antidepressant drug exposure during pregnancy is based on evidence from case-control or cohort studies. Many of these observational studies, during the past decade, examined the risk of autism spectrum disorder (ASD) in exposed offspring. Different studies using different methods and examining different periods of antidepressant exposure before and during pregnancy obtained different results...
September 26, 2017: Journal of Clinical Psychiatry
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