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https://www.readbyqxmd.com/read/28533154/preconception-and-prenatal-genetic-counselling
#1
REVIEW
Adonis S Ioannides
Identifying individuals at risk of having children affected by genetic conditions or congenital anomalies allows counselling that aims to inform reproductive decisions. This process takes place either at the preconception or early prenatal stage, although more options are available if risks are identified before the pregnancy. Preconception counselling covers issues that can affect the health of the mother and baby including folic acid supplementation. Carrier screening for autosomal recessive diseases, such as beta thalassaemia, has resulted in a significantly reduced incidence in many countries...
April 21, 2017: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28526520/preconception-care-among-low-risk-mothers-in-a-french-perinatal-network-frequency-of-utilization-and-factors-associated
#2
Sabrina Paradis, Anne Ego, Jean-Luc Bosson
OBJECTIVE: Determine the frequency of preconception care use in France and factors impacting preconception visit. MATERIALS AND METHODS: An epidemiological study was conducted from September 2015 to October 2015 in 5 maternity hospitals within the "Alpes-Isère" perinatal network, comprising of French-speaking women, with uncomplicated pregnancies, who delivered a healthy term baby (≥ 37 weeks of gestational age). Two groups were compared: patients with and without preconception care...
May 16, 2017: J Gynecol Obstet Hum Reprod
https://www.readbyqxmd.com/read/28524740/identifying-risk-factors-for-late-onset-50-alcohol-use-disorder-and-heavy-drinking-a-systematic-review
#3
Jakob Emiliussen, Anette Søgaard Nielsen, Kjeld Andersen
This systematic review seeks to expand the description and understanding of late-onset AUD and asks "Which risk factors have been reported for late-onset heavy drinking and AUD?" METHOD: Using PRISMA guidelines, a literature review and search was performed on May 19, 2015 using the following databases: MEDLINE, EMBASE, PubMed, and PsychInfo. Nine studies were included in the final review. RESULTS: The search revealed that only very few studies have been conducted...
May 19, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28521194/preconception-care-for-women-with-type-2-diabetes-mellitus-a-mixed-methods-study-of-provider-knowledge-and-practice
#4
J Klein, J A Boyle, R Kirkham, C Connors, C Whitbread, J Oats, F Barzi, D McIntyre, I Lee, M Luey, J Shaw, A D H Brown, L J Maple-Brown
AIMS: Preconception care may decrease adverse pregnancy outcomes associated with pre-existing diabetes mellitus. Aboriginal Australians are at high risk of type 2 diabetes mellitus (T2DM), with earlier onset. We explored practitioner views on preconception care delivery for women with T2DM in the Northern Territory, where 31% of births are to Aboriginal women. METHODS: Mixed-methods study including cross-sectional survey of 156 health practitioners and 11 semi-structured interviews...
May 5, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28520809/antenatal-coffee-and-tea-consumption-and-the-effect-on-birth-outcome-and-hypertensive-pregnancy-disorders
#5
Timothy van der Hoeven, Joyce L Browne, Cuno S P M Uiterwaal, Cornelis K van der Ent, Diederick E Grobbee, Geertje W Dalmeijer
BACKGROUND AND OBJECTIVE: Coffee and tea are commonly consumed during pregnancy. While several of their components, like caffeine, have strong pharmacological effects, the effect on the unborn fetus remains unclear. Caffeine intake has been associated with abortion, preterm birth and fetal growth restriction, but a general consensus on caffeine restriction is still lacking. We aimed to investigate antenatal coffee, tea and caffeine consumption and the effect on birth weight and length, gestational age at birth and hypertensive disorders in pregnancy...
2017: PloS One
https://www.readbyqxmd.com/read/28515209/for-a-healthier-future-a-virtuous-cycle-for-reducing-exposure-to-persistent-organic-pollutants
#6
REVIEW
Chisato Mori, Emiko Todaka
In the modern society, people are exposed to various pollutants during their lifetime. Worldwide, the status of children's health has changed in recent decades. Some studies have attempted to identify the causes of these changes and whether they relate to pollutant exposure; however, such attempts have faced major challenges because human life is complex, involving many social and environmental factors. Several long-term cohort studies are being conducted to determine the relationship between diseases and social and environmental factors in children...
May 17, 2017: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/28495266/maternal-pre-pregnancy-infection-with-hepatitis-b-virus-and-the-risk-of-preterm-birth-a-population-based-cohort-study
#7
Jue Liu, Shikun Zhang, Min Liu, Qiaomei Wang, Haiping Shen, Yiping Zhang
BACKGROUND: Preterm birth is the leading cause of child death in children younger than 5 years. Large cohort studies in developed countries have shown that maternal hepatitis B virus infection is associated with preterm birth, but there is little reliable evidence from China and other developing countries, where hepatitis B virus prevalence is intermediate or high. Hence, we designed this study to investigate the association between pre-pregnancy hepatitis B virus infection and risk of preterm and early preterm birth...
June 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28490512/preconceptional-and-gestational-weight-trajectories-and-risk-of-delivering-a-small-for-gestational-age-baby-in-rural-gambia
#8
William Johnson, Seham Aa Elmrayed, Fatou Sosseh, Andrew M Prentice, Sophie E Moore
Background: Maternal nutritional status is a key determinant of small for gestational age (SGA), but some knowledge gaps remain, particularly regarding the role of the energy balance entering pregnancy.Objective: We investigated how preconceptional and gestational weight trajectories (summarized by individual-level traits) are associated with SGA risk in rural Gambia.Design: The sample comprised 670 women in a trial with serial weight data (7310 observations) that were available before and during pregnancy...
May 10, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28490508/longer-exposure-to-a-new-refugee-food-ration-is-associated-with-reduced-prevalence-of-small-for-gestational-age-results-from-2-cross-sectional-surveys-on-the-thailand-myanmar-border
#9
Verena I Carrara, Wolfgang Stuetz, Sue J Lee, Kanlaya Sriprawat, Basi Po, Borimas Hanboonkunupakarn, François H Nosten, Rose McGready
Background: Despite the high risk of compromised nutrition, evidence of the effect of refugee rations on fetal growth is limited. A new ration containing micronutrient-fortified flour without increased caloric content of the general food basket was introduced to the Maela refugee camp in Thailand, July 2004.Objective: The effect of the length of gestational exposure of the new ration on fetal growth was compared with birth outcomes [small for gestational age (SGA), preterm birth (PTB)].Design: In an observational study in 987 newborns from 1048 prospectively followed antenatal clinic (ANC) attendees enrolled in 2 cross-sectional surveys, exposure was categorized in 2004 according to gestation at the time of commencing the new ration and in 2006 as comprehensive (preconception and pregnancy)...
May 10, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28485707/exploring-the-factors-considered-by-people-living-with-hiv-and-their-partners-during-preconception
#10
V Logan Kennedy, Micaela Collins, Mark H Yudin, Lena Serghides, Sharon Walmsley, Jonathan B Angel, Fanta Ongoiba, Jeff Powis, Fiona Smaill, Wangari Tharao, Anita Rachlis, Michael Silverman, Roger Sandre, Dean A Regier, Mona Loutfy
Data are lacking on factors that may impact conception-related decision-making among individuals living with HIV. This study's aim was to shed light on these considerations. Participants were invited to complete a survey on preconception considerations. A rank-ordered logit model was fit to estimate the relative importance of listed consideration factors; the interaction of HIV status and the factors was assessed. Fifty-nine participants living with HIV and 18 partners (11 HIV-negative participants and 7 living with HIV) were included...
May 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28472208/ambient-air-pollution-and-risk-of-gestational-hypertension
#11
Yeyi Zhu, Cuilin Zhang, Danping Liu, Sandie Ha, Sung Soo Kim, Anna Pollack, Pauline Mendola
Air pollution has been linked to hypertension in the general population, but data on gestational hypertension (GH) are limited. We investigated air pollutants and toxics during preconception and early gestation in relation to GH risk in the Consortium on Safe Labor/Air Quality and Reproductive Health Study (2002-2008). Modified Community Multiscale Air Quality models estimated air pollution exposures among 6,074 singleton pregnancies with GH and 199,980 normotensives. Generalized estimating equations estimated relative risks per interquartile-range increment for pollutants and high exposure (≥75th percentile) for toxics, after adjustment for major risk factors...
May 4, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28469549/repeat-24-hour-recalls-and-locally-developed-food-composition-databases-a-feasible-method-to-estimate-dietary-adequacy-in-a-multi-site-preconception-maternal-nutrition-rct
#12
Rebecca L Lander, K Michael Hambidge, Nancy F Krebs, Jamie E Westcott, Ana Garces, Lester Figueroa, Gabriela Tejeda, Adrien Lokangaka, Tshilenge S Diba, Manjunath S Somannavar, Ranjitha Honnayya, Sumera A Ali, Umber S Khan, Elizabeth M McClure, Vanessa R Thorsten, Kristen B Stolka
Background: Our aim was to utilize a feasible quantitative methodology to estimate the dietary adequacy of >900 first-trimester pregnant women in poor rural areas of the Democratic Republic of the Congo, Guatemala, India and Pakistan. This paper outlines the dietary methods used. Methods: Local nutritionists were trained at the sites by the lead study nutritionist and received ongoing mentoring throughout the study. Training topics focused on the standardized conduct of repeat multiple-pass 24-hr dietary recalls, including interview techniques, estimation of portion sizes, and construction of a unique site-specific food composition database (FCDB)...
2017: Food & Nutrition Research
https://www.readbyqxmd.com/read/28462401/effects-of-exercise-prior-or-during-pregnancy-in-high-fat-diet-fed-mice-alter-bone-gene-expression-of-female-offspring-an-experimental-study
#13
Abbasali Gaeini, Mohamadreza Baghaban Eslaminejad, Siroos Choobineh, Neda Mousavi, Sadegh Satarifard, Leila Shafieineek
BACKGROUND: Based on different studies it was shown that exercise training is an important factor in preconception and prenatal care. OBJECTIVE: The aim of this study was to determine whether regular preconception exercise training with or without exercise training during pregnancy decreases detrimental effects of maternal high fat diet on female offspring bone health. MATERIALS AND METHODS: Twenty-four C57BL/6 female mice were fed high-fat diet (35%) and were randomly divided into four groups: trained in preconception period and exercised during pregnancy (TE); trained in preconception periods but unexercised during pregnancy (TC); untrained in preconception periods but exercised during pregnancy (CE); untrained and unexercised (CC)...
February 2017: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/28440578/developing-social-marketed-individual-preconception-care-consultations-which-consumer-preferences-should-it-meet
#14
Sabine F van Voorst, Chantal A Ten Kate, Lieke C de Jong-Potjer, Eric A P Steegers, Semiha Denktaş
AIMS: Preconception care (PCC) is care that aims to improve the health of offspring by addressing risk factors in the pre-pregnancy period. Consultations are recognized as a method to promote perinatal health. However, prospective parents underutilize PCC services. Uptake can improve if delivery approaches satisfy consumer preferences. Aim of this study was to identify preferences of women (consumers) as a first step to social marketed individual PCC consultations. METHODS: In depth, semi-structured interviews were performed to identify women's views regarding the four components of the social marketing model: product (individual PCC consultation), place (setting), promotion (how women are made aware of the product) and price (costs)...
April 25, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/28440103/british-association-for-psychopharmacology-consensus-guidance-on-the-use-of-psychotropic-medication-preconception-in-pregnancy-and-postpartum-2017
#15
R Hamish McAllister-Williams, David S Baldwin, Roch Cantwell, Abby Easter, Eilish Gilvarry, Vivette Glover, Lucian Green, Alain Gregoire, Louise M Howard, Ian Jones, Hind Khalifeh, Anne Lingford-Hughes, Elizabeth McDonald, Nadia Micali, Carmine M Pariante, Lesley Peters, Ann Roberts, Natalie C Smith, David Taylor, Angelika Wieck, Laura M Yates, Allan H Young
Decisions about the use of psychotropic medication in pregnancy are an ongoing challenge for clinicians and women with mental health problems, owing to the uncertainties around risks of the illness itself to mother and fetus/infant, effectiveness of medications in pregnancy and risks to the fetus/infant from in utero exposure or via breast milk. These consensus guidelines aim to provide pragmatic advice regarding these issues. They are divided into sections on risks of untreated illness in pregnancy; general principles of using drugs in the perinatal period; benefits and harms associated with individual drugs; and recommendations for the management of specific disorders...
March 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28437216/posttraumatic-symptom-reporting-and-reported-cigarette-smoking-during-pregnancy
#16
Sara L Kornfield, Marian Moseley, Dina Appleby, Courtney L McMickens, Mary D Sammel, C Neill Epperson
INTRODUCTION: Increased prevalence of nicotine dependence among individuals suffering from posttraumatic stress disorder (PTSD) is well established. However, there are limited studies on the prevalence of smoking during pregnancy in relation to prepregnancy history of trauma exposures and active PTSD symptoms during pregnancy. Prenatal smoking has been implicated in a host of negative outcomes for mother and baby. Given maternal and fetal risk, it is critical to define predictors of continued cigarette smoking during pregnancy...
February 21, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28432715/complications-of-pregnancy-and-labor-in-women-with-klippel-trenaunay-syndrome-a-nationwide-cross-sectional-study
#17
S E R Horbach, M M Lokhorst, C E U Oduber, S Middeldorp, J A M van der Post, C M A M van der Horst
OBJECTIVE: To evaluate complications of pregnancy, including thromboembolism, in women with extensive vascular malformations associated with Klippel-Trenaunay Syndrome (KTS). DESIGN: Nationwide cross-sectional study. SETTING: Two tertiary expert centers and the Dutch Klippel-Trenaunay patient organization. SAMPLE: Adult women with KTS. METHODS: Patients with KTS were invited to participate in a comprehensive online survey about their obstetric history...
April 22, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28427955/preventing-alcohol-and-tobacco-exposed-pregnancies-choices-plus-in-primary-care
#18
Mary M Velasquez, Kirk L von Sternberg, R Louise Floyd, Danielle Parrish, Alicia Kowalchuk, Nanette S Stephens, Britta Ostermeyer, Charles Green, J Paul Seale, Patricia Dolan Mullen
INTRODUCTION: Alcohol and tobacco use are common among U.S. women, yet if used during pregnancy these substances present significant preventable risks to prenatal and perinatal health. Because use of alcohol and tobacco often continue into the first trimester and beyond, especially among women with unintended pregnancies, effective evidence-based approaches are needed to decrease these risk behaviors. This study was designed to test the efficacy of CHOICES Plus, a preconception intervention for reducing the risk of alcohol- and tobacco-exposed pregnancies (AEPs and TEPs)...
April 17, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28419656/cannabis-psychosis-and-schizophrenia-unravelling-a-complex-interaction
#19
Ian Hamilton
The relationship between cannabis and psychosis and schizophrenia has tested the field of addiction for decades, and in some ways serves as measure of our ability to provide a credible contribution to public health. As cannabis is used widely, many people are interested in the risks the drug poses to mental health. This paper focuses upon a seminal study examining this, the trajectory of subsequent research findings and what this has meant for understanding and communicating risk factor information. These studies provided evidence of a dose-response relationship between cannabis and psychosis, and that for those individuals with schizophrenia cannabis exacerbated their symptoms...
April 16, 2017: Addiction
https://www.readbyqxmd.com/read/28418571/risk-for-autism-spectrum-disorders-according-to-period-of-prenatal-antidepressant-exposure-a-systematic-review-and-meta-analysis
#20
Antonia Mezzacappa, Pierre-Alexandre Lasica, Francesco Gianfagna, Odile Cazas, Patrick Hardy, Bruno Falissard, Anne-Laure Sutter-Dallay, Florence Gressier
Importance: Several studies have examined the links between prenatal exposure to antidepressants and autism spectrum disorders (ASDs) in children, with inconsistent results, especially regarding the impact of the trimester of exposure. Objective: To perform a systematic review of the literature and a meta-analysis of published studies to assess the association between ASDs and fetal exposure to antidepressants during pregnancy for each trimester of pregnancy and preconception...
April 17, 2017: JAMA Pediatrics
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