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https://www.readbyqxmd.com/read/28104242/preconception-stress-and-the-secondary-sex-ratio-in-a-population-based-preconception-cohort
#1
Jisuk Bae, Courtney D Lynch, Sungduk Kim, Rajeshwari Sundaram, Katherine J Sapra, Germaine M Buck Louis
OBJECTIVE: To examine the association between preconception parental stress and the secondary sex ratio, defined as the ratio of males to females at birth. DESIGN: A population-based preconception cohort. SETTING: Not applicable. PATIENT(S): A total of 235 couples who were enrolled before conception in Michigan and Texas between 2005 and 2009 and who had a singleton birth during the follow-up period. Couples were interviewed separately at baseline to obtain information on perceived stress (Cohen's Perceived Stress Scale) and lifetime history of physician-diagnosed anxiety and/or mood disorders...
January 16, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28103463/-uterine-rupture-at-18-weeks-of-pregnancy-in-the-context-of-malformed-uterus
#2
Emídio Vale-Fernandes, Neusa Teixeira, Alexandra Cadilhe, Maria José Rocha
Birth defects of the female genital tract are relatively common and often asymptomatic. Despite the pregnancy outcome can be favorable, adverse obstetric outcomes are described in women with uterine malformations. The authors report the case of an obstetric emergency which enhances the possibility of a very adverse and rare outcome of uterine rupture in a left hemi-cavity of a bicornuate uterus away from the term, at 18 weeks of pregnancy, in a pregnant woman with history of caesarean in the right hemi-cavity and with placenta increta...
October 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28102992/environmental-factors-associated-with-autism-spectrum-disorder-a-scoping-review-for-the-years-2003-2013
#3
M Ng, J G de Montigny, M Ofner, M T Do
INTRODUCTION: The number of children diagnosed with autism spectrum disorder (ASD) has been rapidly rising in the past decade. The etiology of this disorder, however, is largely unknown, although the environmental relative to the genetic contribution is substantial. We conducted a scoping review to comprehensively assess the current state of knowledge of the environmental factors present from preconception to early life associated with ASD, and to identify research gaps. METHODS: We searched electronic databases MEDLINE, PsycINFO and ERIC for articles on potential risk factors or protective factors from the physical and social environments associated with ASD and its subclassifications published between 1 January, 2003, and 12 July, 2013...
January 2017: Health Promotion and Chronic Disease Prevention in Canada
https://www.readbyqxmd.com/read/28078529/rethinking-preconception-care-a-critical-women-s-health-perspective
#4
Erika L Thompson, Coralia Vázquez-Otero, Cheryl A Vamos, Stephanie L Marhefka, Nolan S Kline, Ellen M Daley
Objectives Preconception care aims to provide care to reproductive aged individuals in order to improve pregnancy and birth outcomes. Given that preconception care is a public health priority, it is important to evaluate the evolution of this health paradigm and the promotion of preconception messages that are obtained by the public. We identified online preconception health messages, which were critically assessed through a women's health perspective. Methods We searched for "preconception care" on three major search engines...
January 11, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28056865/why-women-do-not-ask-for-information-on-preconception-health-a-qualitative-study
#5
Renata Bortolus, Nadia C Oprandi, Francesca Rech Morassutti, Luca Marchetto, Francesca Filippini, Eleonora Agricola, Alberto E Tozzi, Carlo Castellani, Faustina Lalatta, Bruno Rusticali, Pierpaolo Mastroiacovo
BACKGROUND: Preconception care involves health promotion to reduce risk factors that might affect women and couples of childbearing age. The risk factors of adverse reproductive outcomes include recognized genetic diseases in the family or the individual, previous congenital diseases, miscarriage, prematurity, fetal growth restriction, infertility, chronic maternal diseases, lifestyle, and occupational or environmental factors. Effective preconception care involves a range of preventive, therapeutic and behavioural interventions...
January 5, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28048902/we-g-brc-00-experiences-with-tg100-in-clinical-use
#6
Grace Gwe-Ya Kim
: Failure Mode and Effects Analysis (FMEA) originated as an industrial engineering technique used for risk management and safety improvement of complex processes. In the context of radiotherapy, the AAPM Task Group 100 advocates FMEA as the framework of choice for establishing clinical quality management protocols. However, there is concern that widespread adoption of FMEA in radiation oncology will be hampered by the perception that implementation of the tool will have a steep learning curve, be extremely time consuming and labor intensive, and require additional resources...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048251/we-g-brc-01-risk-assessment-for-radiosurgery
#7
G Kim
: Failure Mode and Effects Analysis (FMEA) originated as an industrial engineering technique used for risk management and safety improvement of complex processes. In the context of radiotherapy, the AAPM Task Group 100 advocates FMEA as the framework of choice for establishing clinical quality management protocols. However, there is concern that widespread adoption of FMEA in radiation oncology will be hampered by the perception that implementation of the tool will have a steep learning curve, be extremely time consuming and labor intensive, and require additional resources...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047604/we-g-brc-02-risk-assessment-for-hdr-brachytherapy
#8
J Mayadev
: Failure Mode and Effects Analysis (FMEA) originated as an industrial engineering technique used for risk management and safety improvement of complex processes. In the context of radiotherapy, the AAPM Task Group 100 advocates FMEA as the framework of choice for establishing clinical quality management protocols. However, there is concern that widespread adoption of FMEA in radiation oncology will be hampered by the perception that implementation of the tool will have a steep learning curve, be extremely time consuming and labor intensive, and require additional resources...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046955/we-g-brc-03-risk-assessment-for-physics-plan-review
#9
S Parker
: Failure Mode and Effects Analysis (FMEA) originated as an industrial engineering technique used for risk management and safety improvement of complex processes. In the context of radiotherapy, the AAPM Task Group 100 advocates FMEA as the framework of choice for establishing clinical quality management protocols. However, there is concern that widespread adoption of FMEA in radiation oncology will be hampered by the perception that implementation of the tool will have a steep learning curve, be extremely time consuming and labor intensive, and require additional resources...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28040641/psychopharmacological-drug-utilization-patterns-in-pregnant-women-with-bipolar-disorder-a-nationwide-register-based-study
#10
S C Broeks, H Thisted Horsdal, K Glejsted Ingstrup, C Gasse
BACKGROUND: Bipolar disorder is often associated with a lifetime indication for treatment with psychotropic drugs, thus pregnant women face the dilemma whether to continue treatment or not. This study describes the psychopharmacological drug utilization patterns among women with bipolar disorder from 12 months preconception to 12 months postpartum. METHODS: We conducted a register-based cohort study among all Danish women aged 15-55 with a diagnosis of bipolar disorder, who gave birth to their first and singleton child between January 1997 and December 2012...
December 8, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28039875/first-trimester-isolated-maternal-hypothyroxinemia-adverse-maternal-metabolic-profile-and-impact-on-the-obstetrical-outcome
#11
Raluca Maria Furnica, Damien Gruson, John H Lazarus, Dominique Maiter, Pierre Bernard, Chantal Daumerie
BACKGROUND: Isolated maternal hypothyroxinemia (IH) is defined as low maternal FT4 (<5(th) percentile) and normal TSH. There is concern on its potential negative effects on the mother and offspring. OBJECTIVE: We aimed to evaluate the prevalence of IH and to assess the consequences of hypothyroxinemia on the maternal and foetal outcomes. SUBJECTS AND METHODS: From a total of 1300 consecutive pregnant women recruited during the prenatal screen (mean gestational age, 11...
December 31, 2016: Clinical Endocrinology
https://www.readbyqxmd.com/read/28031048/china-s-community-based-strategy-of-universal-preconception-care-in-rural-areas-at-a-population-level-using-a-novel-risk-classification-system-for-stratifying-couples%C3%A2-preconception-health-status
#12
Qiongjie Zhou, Shikun Zhang, Qiaomei Wang, Haiping Shen, Weidong Tian, Jingqi Chen, Ganesh Acharya, Xiaotian Li
BACKGROUND: Preconception care (PCC) is recommended for optimizing a woman's health prior to pregnancy to minimize the risk of adverse pregnancy and birth outcomes. We aimed to evaluate the impact of strategy and a novel risk classification model of China´s "National Preconception Health Care Project" (NPHCP) in identifying risk factors and stratifying couples' preconception health status. METHODS: We performed a secondary analysis of data collected by NPHCP during April 2010 to December 2012 in 220 selected counties in China...
December 28, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/28026098/risk-factors-for-preeclampsia-in-infertile-chinese-women-with-polycystic-ovary-syndrome-a-prospective-cohort-study
#13
Hexia Xia, Ruixiu Zhang, Xiaoli Sun, Lu Wang, Wei Zhang
To explore preconception risk factors for preeclampsia (PE) in women with polycystic ovary syndrome (PCOS), a prospective cohort study was conducted in 92 infertile Chinese women with PCOS who had a singleton pregnancy by ovulation induction and were followed up for 6 weeks after delivery. The patients underwent assessment of physical, endocrine, and metabolic features before ovulation induction. Fifteen (16.3%) patients were diagnosed with PE. Logistic regression analysis showed that preconception sex hormone-binding globulin (SHBG), insulin level at 120 minutes, and body mass index were three independent risk factors for PE (odds ratio [OR], 0...
December 27, 2016: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28012606/could-ethanol-induced-alterations-in-the-expression-of-glutamate-transporters-in-testes-contribute-to-the-effect-of-paternal-drinking-on-the-risk-of-abnormalities-in-the-offspring
#14
Mohammed Abul Kashem, Aven Lee, David V Pow, Omar Šerý, Vladimir J Balcar
It has been known that a preconception paternal alcoholism impacts adversely on the offspring but the mechanism of the effect is uncertain. Several findings suggest that there are signalling systems in testis that are analogous to those known to be altered by alcoholism in brain. We propose that chronic alcohol affects these systems in a manner similar to that in brain. Specifically, we hypothesise that excessive alcohol may disturb glutamatergic-like signalling in testis by increasing expression of the glutamate transporter GLAST (EAAT1)...
January 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28001172/pregnancy-after-kidney-transplantation-high-rates-of-maternal-complications
#15
Cristina Candido, Marina Pontello Cristelli, Ana Raquel Fernandes, Andre Caires Alvino de Lima, Laila Almeida Viana, Jussara L Sato, Nelson Sass, Helio Tedesco-Silva, Jose Osmar Medina-Pestana
INTRODUCTION: Women regain fertility a few time after renal transplantation. However, viability of pregnancy and maternal complications are still unclear. OBJECTIVE: To describe the outcomes of pregnancies in kidney transplanted patients, focusing on maternal complications. METHODS: Retrospective study of pregnancies in kidney transplanted patients between 2004 and 2014, followed up 12 months after delivery. Each pregnancy was considered an event...
December 2016: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/27995520/effect-of-medications-for-gastric-acid-related-symptoms-on-total-motile-sperm-count-and-concentration-a-case-control-study-in-men-of-subfertile-couples-from-the-netherlands
#16
Nicole A Huijgen, Hedwig J Goijen, John M Twigt, Annemarie G M G J Mulders, Jan Lindemans, Gert R Dohle, Joop S E Laven, Régine P M Steegers-Theunissen
INTRODUCTION: Gastric acid-related symptoms are highly prevalent in the general population (21-40%), and more than 11% of individuals use medication for the treatment of these symptoms. The uptake of micronutrients is dependent on the gastrointestinal potential of hydrogen (pH). OBJECTIVE: We hypothesized that medication affecting gastrointestinal pH reduces the availability of B vitamins, thereby deranging one-carbon metabolism and detrimentally affecting spermatogenesis...
December 19, 2016: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/27990841/management-of-pregnancy-in-cardiomyopathies-and-heart-failure
#17
Enrica Golia, Rita Gravino, Alessandra Rea, Daniele Masarone, Marta Rubino, Annapaola Cirillo, Roberta Pacileo, Fiorella Fratta, Maria Giovanna Russo, Giuseppe Pacileo, Giuseppe Limongelli
Pregnancy exposes women with inherited cardiomyopathies to increased risk for arrhythmias and heart failure. In asymptomatic patients with inherited cardiomyopathies, pregnancy is generally well tolerated. Preconception evaluation, risk assessment and proper counseling by a team of experienced physicians are mandatory in managing women with inherited cardiomyopathies planning pregnancy. In this paper, we reviewed the clinical course, risk assessment and management during pregnancy of women with cardiomyopathies...
January 2017: Future Cardiology
https://www.readbyqxmd.com/read/27968954/childhood-leukemia-and-primary-prevention
#18
Todd P Whitehead, Catherine Metayer, Joseph L Wiemels, Amanda W Singer, Mark D Miller
Leukemia is the most common pediatric cancer, affecting 3800 children per year in the United States. Its annual incidence has increased over the last decades, especially among Latinos. Although most children diagnosed with leukemia are now cured, many suffer long-term complications, and primary prevention efforts are urgently needed. The early onset of leukemia-usually before 5 years of age-and the presence at birth of "pre-leukemic" genetic signatures indicate that pre- and postnatal events are critical to the development of the disease...
October 2016: Current Problems in Pediatric and Adolescent Health Care
https://www.readbyqxmd.com/read/27968911/folic-acid-supplementation-birth-defects-and-adverse-pregnancy-outcomes-in-chinese-women-a-population-based-mega-cohort-study
#19
Yuan He, An Pan, Frank B Hu, Xu Ma
BACKGROUND: Periconceptional folic acid use has been widely recommended to reduce risk of neural tube defects. However, the effect on other birth defects and adverse pregnancy outcomes, as well as the time window of folic acid use, needs further investigation. Our study aimed to comprehensively assess the effect of periconceptional folic acid use on pregnancy outcomes in a mega-cohort of women of reproductive age. METHODS: The China National Free Preconception Health Examination Project (NFPHEP) was established in 2010 to assess couples who planned to get pregnant within 4-6 months for pre-pregnancy risk factors for birth defects, and was a national project for all couples in 31 provinces...
October 2016: Lancet
https://www.readbyqxmd.com/read/27964723/fertility-awareness-and-attitudes-towards-parenthood-among-danish%C3%A2-university-college-students
#20
Nina Olsén Sørensen, Signe Marcussen, Mette Grønbæk Backhausen, Mette Juhl, Lone Schmidt, Tanja Tydén, Hanne Kristine Hegaard
BACKGROUND: Postponing parenthood has steadily increased during the past decades in Western countries. This trend has affected the size of families in the direction of fewer children born per couple. In addition, higher maternal age is associated with an increased risk of pregnancy-related complications such as prematurity and foetal death, while higher paternal age increases the risk of miscarriage and affects time-to-pregnancy. Hence, understanding the circumstances and reflections that influence the decision is greatly needed and little is known about potential gender difference influencing the choice...
December 13, 2016: Reproductive Health
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