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https://www.readbyqxmd.com/read/28433734/prospective-association-of-fetal-liver-blood-flow-at-30-weeks-gestation-with-newborn-adiposity
#1
Satoru Ikenoue, Feizal Waffarn, Masanao Ohashi, Kaeko Sumiyoshi, Chigusa Ikenoue, Claudia Buss, Daniel L Gillen, Hyagriv N Simhan, Sonja Entringer, Pathik D Wadhwa
BACKGROUND: The production of variation in adipose tissue accretion represents a key fetal adaptation to energy substrate availability during gestation. Because umbilical venous blood transports nutrient substrate from the maternal to the fetal compartment, and the fetal liver is the primary organ where nutrient inter-conversion occurs, it has been proposed that variations in the relative distribution of umbilical venous blood flow shunting either through ductus venosus or perfusing the fetal liver represents a mechanism underlying this adaptation...
April 19, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28429908/pre-pregnancy-body-mass-index-as-a-predictor-of-low-birth-weight-infants-in-japan
#2
Utako Murai, Kyoko Nomura, Michiko Kido, Takeaki Takeuchi, Mitsuhiro Sugimoto, Mahbubur Rahman
BACKGROUND AND OBJECTIVES: The prevalence of low birth weight (LBW) infants in Japan has doubled in the last several decades. The objective of this study was to examine the effects of pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) on LBW infants of Japanese women. METHODS AND STUDY DESIGN: This retrospective study was conducted using data on 1,336 mothers (mean age, 34.0 years)whose pre-pregnancy BMI was less than 23 kg/m2 and their singleton infants were born at full term between January and December in 2011...
May 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28422347/serum-placental-growth-factor-and-soluble-fms-like-tyrosine-kinase-1-at-mid-gestation-in-healthy-women-association-with-small-for-gestational-age-neonates
#3
Itsuko Furuta, Takeshi Umazume, Takashi Kojima, Kentaro Chiba, Kinuko Nakagawa, Ami Hosokawa, Satoshi Ishikawa, Takahiro Yamada, Mamoru Morikawa, Hisanori Minakami
AIM: This study was performed to determine the associations between serum placental growth factor (PlGF) and soluble fms-like tyrosine kinase 1 (sFlt-1) levels at mid-gestation with the risk of small-for-gestational-age (SGA) neonates born at gestational week (GW) ≥ 36 in healthy women. METHODS: PlGF and sFlt-1 concentrations were determined at GW 24-27 in 183 women with births at GW ≥ 36, but without gestational diabetes mellitus and hypertension. RESULTS: Thirteen (7...
April 19, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28419655/cytokine-and-adipokine-are-biofactors-can-act-in-blood-and-colostrum-of-obese-mothers
#4
Mahmi Fujimori, Eduardo Luzia França, Tassiane Cristina Morais, Vanessa Fiorin, Luiz Carlos de Abreu, Adenilda Cristina Honório-França
Breast milk contains bioactive components that contribute to newborn development. However, colostrum may undergo biochemical and immunological changes as a function of maternal overweight and obesity. To investigate this hypothesis, this study determined the levels of hormones and immunological markers in the serum and colostrum of overweight and obese mothers. Colostrum and serum samples were collected from 15 normoweight, 15 overweight, and 15 obese women for determination of leptin, adiponectin, cytokines (TNF-α, IL-6, IL-10), and C-reactive protein (CRP)...
March 2017: BioFactors
https://www.readbyqxmd.com/read/28404514/postpartum-glucose-testing-related-factors-and-progression-to-abnormal-glucose-tolerance-in-a-rural-population-with-a-known-history-of-gestational-diabetes
#5
Haydeh Ghajari, Sedigheh Nouhjah, Hajieh Shahbazian, Rohollah Valizadeh, Noorollah Tahery
AIMS: Gestational diabetes is a strong risk factor for postpartum progression to glucose intolerance. The aims of the study were to determine rate of postpartum glucose testing , its related factors and rate of progression to glucose intolerance in women who underwent postpartum glucose testing after pregnancy that complicated by gestational diabetes. MATERIALS: this is a retrospective study and women with gestational diabetes who received prenatal care during 2005-2015 in 3 rural health centers of Khuramshahr (southwestern of Iran) were enrolled...
April 3, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28403953/risk-factors-of-preterm-birth-in-france-in-2010-and-changes-since-1995-results-from-the-french-national-perinatal-surveys
#6
C Prunet, M Delnord, M-J Saurel-Cubizolles, F Goffinet, B Blondel
OBJECTIVES: To investigate risk factors of total, spontaneous and induced preterm birth in 2010 and differences between 1995 and 2010. MATERIAL AND METHODS: The national perinatal surveys are based on a representative sample of births in France. We selected live-born singletons (n=14,326 in 2010 and 12,885 in 1995) and used multiple regression analyses to calculate adjusted odds ratios (aOR) for maternal sociodemographic characteristics, obstetric history, prenatal care and smoking...
January 2017: J Gynecol Obstet Hum Reprod
https://www.readbyqxmd.com/read/28399857/variability-and-predictors-of-urinary-concentrations-of-organophosphate-flame-retardant-metabolites-among-pregnant-women-in-rhode-island
#7
Megan E Romano, Nicola L Hawley, Melissa Eliot, Antonia M Calafat, Nayana K Jayatilaka, Karl Kelsey, Stephen McGarvey, Maureen G Phipps, David A Savitz, Erika F Werner, Joseph M Braun
BACKGROUND: Organophospate flame retardants (PFRs) are chemicals of emerging concern due to restrictions on polybrominated diphenyl ether flame retardant formulations. We describe the occurrence, variability, and predictors of urinary metabolites of PFRs among pregnant women. METHODS: In 2014-2015, 59 women from Providence, RI provided up to 3 spot urine samples during pregnancy (~12, 28, and 35 weeks' gestation). We created a pooled urine sample per woman and measured nine relevant metabolites in individual and pooled samples...
April 11, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28399474/exploring-knowledge-of-pre-eclampsia-and-views-on-a-potential-screening-test-in-women-with-type-1-diabetes
#8
Amy C Wotherspoon, Ian S Young, David R McCance, Valerie A Holmes
OBJECTIVE: to explore knowledge of pre-eclampsia and opinions on potential screening tests for pre-eclampsia in women with type 1 diabetes. DESIGN: a qualitative study using semi-structured interviews of women planning a pregnancy, currently pregnant or post-partum with experience of pre-eclampsia. SETTING, PARTICIPANTS AND METHODS: eleven women with type 1 diabetes were recruited from a pre-pregnancy planning clinic or antenatal clinic. Semi-structured interviews were conducted with the women, asking a series of open-ended questions about their current knowledge of pre-eclampsia and their views on screening for pre-eclampsia...
March 30, 2017: Midwifery
https://www.readbyqxmd.com/read/28399116/maternal-pre-pregnancy-body-mass-index-and-risk-of-bronchopulmonary-dysplasia
#9
Suzan L Carmichael, Peiyi Kan, Jeffrey B Gould, David K Stevenson, Gary M Shaw, Henry C Lee
BACKGROUND: We examined the relationship between women's prepregnancy body mass index (BMI) and development of bronchopulmonary dysplasia (BPD) in their preterm offspring, hypothesizing that obesity-associated inflammation may increase risk. METHODS: We studied infants born in California 2007-2011, using linked data from California Perinatal Quality Care Collaborative neonatal intensive care units, hospital discharge, and vital statistics. We included infants with birthweight<1500 grams or gestational age at birth 22-29 weeks...
April 11, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28393324/maternal-prenatal-stress-and-other-developmental-risk-factors-for-adolescent-depression-spotlight-on-sex-differences
#10
Seth D Maxwell, Anna M Fineberg, Deborah A Drabick, Shannon K Murphy, Lauren M Ellman
Maternal stress during pregnancy has been linked to premorbid abnormalities associated with depression (e.g., difficult temperament, cognitive deficits) in offspring. However, few studies have looked across developmental periods to examine maternal stress during pregnancy and offspring depression during adolescence and whether these associations differ by sex. The current study used data from 1711 mother-offspring dyads (offspring sex: 49.8% male) in a longitudinal birth cohort study. Maternal narratives collected during pregnancy were qualitatively coded for stress-related themes by independent raters...
April 10, 2017: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/28391337/managing-glomerular-disease-in-pregnancy
#11
Michelle A Hladunewich, Kate Bramham, Belinda Jim, Sharon Maynard
Glomerular disease, especially lupus nephritis, is common in young women of childbearing age. As such, practicing nephrologists must have adequate knowledge and expertise to prepare these women for pregnancy, to diagnose and manage the numerous pregnancy-associated complications that are common in this vulnerable patient population and finally to support these young women who often struggle to manage both their young children along with an often onerous chronic disease. In this article we will review the pre-pregnancy counseling these women should ideally receive to allow them to make an informed decision about proceeding with a pregnancy, an approach to the diagnosis of pregnancy-associated worsening of kidney function and proteinuria as well as pregnancy-safe management strategies, including immunosuppression, antihypertensive agents and other medications necessary for the management of nephrotic syndrome...
January 1, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28386955/adult-pre-pregnancy-weight-change-and-risk-of-developing-hypertensive-disorders-in-pregnancy
#12
Akilew A Adane, Gita D Mishra, Leigh R Tooth
BACKGROUND: While the association of pre-pregnancy body mass index (BMI) and hypertensive disorders in pregnancy (HDP) is well documented, little is known about the relationship between pre-pregnancy weight change and HDP. We examined the impact of adult pre-pregnancy weight change on the development of HDP. METHODS: We included 2914 women, surveyed about every three years since 1996, from the 1973-78 cohort of the Australian Longitudinal Study on Women's Health...
April 7, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28384582/dioxins-furans-and-pcbs-in-canadian-human-milk-2008-2011
#13
Dorothea F K Rawn, Amy R Sadler, Valerie A Casey, François Breton, Wing-Fung Sun, Tye E Arbuckle, William D Fraser
Human milk was collected between 2008 and 2011 as part of the Maternal - Infant Research on Environmental Chemicals (MIREC) study that was initiated to establish Canadian national estimates of maternal and infant exposure to a broad suite of environmental contaminants (e.g., persistent organic pollutants [POPs], trace elements, phthalates, etc.). Among the 1017 human milk samples collected, 298 were analysed for polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs)...
April 3, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28379183/rapid-identification-of-pathogenic-variants-in-two-cases-of-charcot-marie-tooth-disease-by-gene-panel-sequencing
#14
Chi-Chun Ho, Shuk-Mui Tai, Edmond Chi-Nam Lee, Timothy Shin-Heng Mak, Timothy Kam-Tim Liu, Victor Wai-Lun Tang, Wing-Tat Poon
Charcot-Marie-Tooth disease (CMT) is a common inherited peripheral neuropathy affecting up to 1 in 1214 of the general population with more than 60 nuclear genes implicated in its pathogenesis. Traditional molecular diagnostic pathways based on relative prevalence and clinical phenotyping are limited by long turnaround time, population-specific prevalence of causative variants and inability to assess multiple co-existing variants. In this study, a CMT gene panel comprising 27 genes was used to uncover the pathogenic mutations in two index patients...
April 5, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28377190/pre-pregnancy-counseling-for-women-with-heart-disease-a-prospective-study
#15
M Cauldwell, P J Steer, L Swan, R R Patel, M A Gatzoulis, A Uebing, M R Johnson
BACKGROUND: Women with cardiac disease and their infants are at a greater risk of mortality and morbidity during pregnancy. Expert groups recommend preconception counseling (PCC) for all women with cardiac disease so they are made aware of these risks. We have run a specialist maternal cardiac clinic since 1996. The aim of this study was to evaluate the experience of women who have received PCC within an established multidisciplinary tertiary clinic and to establish their views regarding the counseling they received...
March 30, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28376732/changes-in-fruit-and-vegetable-consumption-habits-from-pre-pregnancy-to-early-pregnancy-among-norwegian-women
#16
Marianne Skreden, Elling Bere, Linda R Sagedal, Ingvild Vistad, Nina C Øverby
BACKGROUND: A healthy diet is important for pregnancy outcome and the current and future health of woman and child. The aims of the study were to explore the changes from pre-pregnancy to early pregnancy in consumption of fruits and vegetables (FV), and to describe associations with maternal educational level, body mass index (BMI) and age. METHODS: Healthy nulliparous women were included in the Norwegian Fit for Delivery (NFFD) trial from September 2009 to February 2013, recruited from eight antenatal clinics in southern Norway...
April 4, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28368304/pre-pregnancy-body-mass-index-is-associated-with-dietary-inflammatory-index-and-c-reactive-protein-concentrations-during-pregnancy
#17
Dayeon Shin, Junguk Hur, Eun-Hee Cho, Hae-Kyung Chung, Nitin Shivappa, Michael D Wirth, James R Hébert, Kyung Won Lee
There have been a limited number of studies examining the association between pre-pregnancy body mass index (BMI) and dietary inflammation during pregnancy. Our aim is to examine the association between pre-pregnancy BMI and the Dietary Inflammatory Index (DII)™ and C-reactive protein (CRP) concentrations during pregnancy. The study included 631 pregnant American women from the National Health and Nutrition Examination Survey (NHANES) cross-sectional examinations from 2003 to 2012. Pre-pregnancy BMI was calculated based on self-reported pre-pregnancy weight and measured height...
April 1, 2017: Nutrients
https://www.readbyqxmd.com/read/28364636/associations-of-maternal-obesity-and-excessive-weight-gain-during-pregnancy-with-subcutaneous-fat-mass-in-infancy
#18
Varsha V Jharap, Susana Santos, Eric A P Steegers, Vincent W V Jaddoe, Romy Gaillard
BACKGROUND: Not much is known about the associations of maternal obesity and excessive gestational weight gain with body fat in infancy. OBJECTIVE: To examine the associations of maternal pre-pregnancy body mass index and gestational weight gain with infant subcutaneous fat. METHODS: In a population-based prospective cohort study among 845 mothers and their infants, we obtained maternal pre-pregnancy body mass index and measured maternal weight during pregnancy...
March 29, 2017: Early Human Development
https://www.readbyqxmd.com/read/28355684/-reference-ranges-of-gestational-weight-gain-in-chinese-population-on-the-incidence-of-macrosomia-a-multi-center-cross-sectional-survey
#19
H Liang, W Y Zhang, X T Li
Objective: To investigate the influence of gestational weight gain (GWG) on the incidence of macrosomia, and to establish the reference ranges of GWG based on the incidence of macrosomia. Methods: A multicenter, cross-sectional study was conducted. Totally, 112 485 women were recruited from 39 hospitals in 14 provinces in China. Totally, 61 149 cases were eligible with singleton pregnancies and non-premature deliveries. The associations of pre-pregnancy body mass index (BMI), GWG, newborn gender and gestational diabetes with macrosomia were analyzed with logistic regression...
March 25, 2017: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/28353072/changes-in-plasma-concentrations-of-25-hydroxyvitamin-d-and-1-25-dihydroxyvitamin-d-during-pregnancy-a-brazilian-cohort
#20
Amanda C Cunha Figueiredo, Paula Guedes Cocate, Amanda R Amorim Adegboye, Ana Beatriz Franco-Sena, Dayana R Farias, Maria Beatriz Trindade de Castro, Alex Brito, Lindsay H Allen, Rana R Mokhtar, Michael F Holick, Gilberto Kac
PURPOSE: To characterize the physiological changes in 25-hydroxyvitamin D [25(OH)D] and 1,25-dihydroxyvitamin D [1,25(OH)2D] throughout pregnancy. METHODS: Prospective cohort of 229 apparently healthy pregnant women followed at 5th-13th, 20th-26th, and 30th-36th gestational weeks. 25(OH)D and 1,25(OH)2D concentrations were measured by LC-MS/MS. Statistical analyses included longitudinal linear mixed-effects models adjusted for parity, season, education, self-reported skin color, and pre-pregnancy BMI...
March 28, 2017: European Journal of Nutrition
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