keyword
https://read.qxmd.com/read/37564464/the-benefit-of-youtube-videos-as-a-source-of-information-on-tinnitus-for-patients
#21
JOURNAL ARTICLE
Satvinder Singh Bakshi, Vinoth Kumar Kalidoss, Seepana Ramesh, Soumyajit Das
Introduction  Tinnitus is one of the most common otological complaints encountered. Patients often use the internet, especially YouTube videos, as a source of information regarding their health condition. There is a need to analyze the standard and quality of information in these videos so that the patients receive correct information. Objective  The purpose of the present study was to evaluate the reliability and utility of YouTube videos on tinnitus. Methods  The first 100 videos on YouTube using the search terms tinnitus and ringing in the ear were identified...
July 2023: International Archives of Otorhinolaryngology
https://read.qxmd.com/read/37505901/emerging-concepts-in-the-detection-of-liver-fibrosis-in-non-alcoholic-fatty-liver-disease
#22
REVIEW
Angelo Armandi, Maurice Michel, Kamela Gjini, Tilman Emrich, Elisabetta Bugianesi, Jörn M Schattenberg
INTRODUCTION: The non-invasive identification of liver fibrosis related to Non-Alcoholic Fatty Liver Disease is crucial for risk-stratification of patients. Currently, the reference standard to stage hepatic fibrosis relies on liver biopsy, but multiple approaches are developed to allow for non-invasive diagnosis and risk stratification. Non-invasive tests, including blood-based scores and vibration-controlled transient elastography, have been widely validated and represent a good surrogate for risk stratification according to recent European and American guidelines...
July 28, 2023: Expert Review of Molecular Diagnostics
https://read.qxmd.com/read/37439590/is-suicide-a-mental-health-public-health-or-societal-problem
#23
REVIEW
Digvijay Goel, Brian Dennis, Sarah K McKenzie
PURPOSE OF REVIEW: Suicide is a complex phenomenon wherein multiple parameters intersect: psychological, medical, moral, religious, social, economic and political. Over the decades, however, it has been increasingly and almost exclusively come to be viewed through a biomedical prism. Colonized thus by health and more specifically mental health professionals, alternative and complimentary approaches have been excluded from the discourse. The review questions many basic premises, which have been taken as given in this context, particularly the '90 percent statistic' derived from methodologically flawed psychological autopsy studies...
September 1, 2023: Current Opinion in Psychiatry
https://read.qxmd.com/read/37410056/copper-mediated-dehydrogenative-c-sp-3-h-borylation-of-alkanes
#24
JOURNAL ARTICLE
Ruocheng Sang, Wangyujing Han, Hanwen Zhang, Carla M Saunders, Adam Noble, Varinder K Aggarwal
Borylations of inert carbon-hydrogen bonds are highly useful for transforming feedstock chemicals into versatile organoboron reagents. Catalysis of these reactions has historically relied on precious-metal complexes, which promote dehydrogenative borylations with diboron reagents under oxidant-free conditions. Recently, photoinduced radical-mediated borylations involving hydrogen atom transfer pathways have emerged as attractive alternatives because they provide complimentary regioselectivities and proceed under metal-free conditions...
July 6, 2023: Journal of the American Chemical Society
https://read.qxmd.com/read/37326432/direct-light-enabled-access-to-%C3%AE-boryl-radicals-application-in-the-stereodivergent-synthesis-of-allyl-boronic-esters
#25
JOURNAL ARTICLE
Alessandro Marotta, Hao Fang, Callum E Adams, Kailey Sun Marcus, Constantin G Daniliuc, John Molloy
Operationally simple strategies to assemble boron containing organic frameworks are highly enabling in organic synthesis. While conventional retrosynthetic logic has engendered many platforms focusing on the direct formation of C-B bonds, α-boryl radicals have recently reemerged as versatile open-shell alternatives to access organoborons via adjacent C-C bond formation. Direct light-enabled α-activation is currently contingent on photo- or transition metal-catalysis activation to efficiently generate radical species...
June 16, 2023: Angewandte Chemie
https://read.qxmd.com/read/37324367/comparison-of-hysterosalpingography-and-laparoscopy-in-the-evaluation-of-infertility-a-prospective-study
#26
JOURNAL ARTICLE
Priyanka Sharma, S Sunita, Namrata Shrivastava, Meena Bhargava
BACKGROUND: Worldwide one of the major problems of human reproduction that haunts men and women is infertility . Hysterosalpingography (HSG) and laparoscopy (LS) are the two most important modalities to evaluate infertility. Our aim is to compare the efficacy of both. METHODOLOGY: This is a prospective study. One hundred and five females of both primary and secondary infertility together were included. Detailed history, examination and routine investigations were carried out...
June 2023: Journal of Obstetrics and Gynaecology of India
https://read.qxmd.com/read/37315115/molecular-advances-in-the-treatment-of-advanced-gastrointestinal-stromal-tumor
#27
JOURNAL ARTICLE
Vinayak Venkataraman, Suzanne George, Gregory M Cote
Most gastrointestinal stromal tumors (GIST) are driven by activating mutations in Proto-oncogene c-KIT (KIT) or PDGFRA receptor tyrosine kinases (RTK). The emergence of effective therapies targeting these mutations has revolutionized the management of advanced GIST. However, following initiation of first-line imatinib, a tyrosine kinase inhibitor (TKI), nearly all patients will develop resistance within 2 years through the emergence of secondary resistance mutations in KIT, typically in the Adenosine Triphosphate (ATP)-binding site or activation loop of the kinase domain...
June 14, 2023: Oncologist
https://read.qxmd.com/read/37275212/online-deployment-of-an-o-pls-model-for-dielectric-spectroscopy-based-inline-monitoring-of-viable-cell-concentrations-in-chinese-hamster-ovary-cell-perfusion-cultivations
#28
JOURNAL ARTICLE
Johannes Lemke, Robert Söldner, Jonas Austerjost
Viable cell concentration (VCC) is an essential parameter that is required to support the efficient cultivation of mammalian cells. Although commonly determined using at-line or off-line analytics, in-line capacitance measurements represent a suitable alternative method for the determination of VCC. In addition, these latter efforts are complimentary with the Food and Drug Administration's initiative for process analytical technologies (PATs). However, current applications for online determination of the VCC often rely on single frequency measurements and corresponding linear regression models...
June 2023: Engineering in Life Sciences
https://read.qxmd.com/read/37243170/targeting-the-host-mitochondria-as-a-novel-human-cytomegalovirus-antiviral-strategy
#29
REVIEW
Lauryn O Bachman, Kevin J Zwezdaryk
Human cytomegalovirus (HCMV) exploits host mitochondrial function to promote viral replication. HCMV gene products have been described to directly interact and alter functional or structural aspects of host mitochondria. Current antivirals against HCMV, such as ganciclovir and letermovir, are designed against viral targets. Concerns with the current antivirals include toxicity and viral resistance. Targeting host mitochondrial function is a promising alternative or complimentary antiviral approach as (1) drugs targeting host mitochondrial function interact with host targets, minimizing viral resistance, and (2) host mitochondrial metabolism plays key roles in HCMV replication...
April 28, 2023: Viruses
https://read.qxmd.com/read/37175176/the-effects-of-essential-oils-on-the-nervous-system-a-scoping-review
#30
REVIEW
Apsorn Sattayakhom, Sineewanlaya Wichit, Phanit Koomhin
Essential oils are a mixture of natural aromatic volatile oils extracted from plants. The use of essential oils is ancient, and has prevailed in different cultures around the world, such as those of the Egyptians, Greeks, Persians, and Chinese. Today, essential oils are used in traditional and complimentary medicines, aromatherapy, massage therapies, cosmetics, perfumes and food industries. The screening effect of essential oils has been studied worldwide. They demonstrate a range of biological activities, such as antiparasitic, antifungal, antibacterial, antiviral, antioxidant, anti-inflammatory, anticancer, antiaging, and neuroprotective properties...
April 27, 2023: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/37154031/early-covid-19-home-based-care-knowledge-and-efficacies-comparing-ghanaian-and-us-respondents
#31
JOURNAL ARTICLE
Esi E Thompson
Home-based care messages were part of behavioral modification interventions to mitigate COVID-19 spread early in the pandemic. What remains unclear is the types of home-based care knowledge people have and whether different kinds of home-based care knowledge influence a person's self-efficacy and response efficacy in managing mild cases. Using a cross-sectional online survey, this exploratory study investigated differences in biomedical and alternative knowledge about COVID-19 home-based care and their association with self and response efficacy from respondents in Ghana and the US...
May 8, 2023: Journal of Health Communication
https://read.qxmd.com/read/36877706/integrating-technologies-provides-insight-into-the-subsurface-foraging-behaviour-of-a-humpback-whale-megaptera-novaeangliae-feeding-on-walleye-pollock-gadus-chalcogrammus-in-juan-de-fuca-strait-canada
#32
JOURNAL ARTICLE
Rhonda Reidy, Stéphane Gauthier, Thomas Doniol-Valcroze, Matthew A Lemay, Rute B G Clemente-Carvalho, Laura L E Cowen, Francis Juanes
Subsurface foraging is an important proportion of the activity budget of rorqual whales, yet information on their behaviour underwater remains challenging to obtain. Rorquals are assumed to feed throughout the water column and to select prey as a function of depth, availability and density, but there remain limitations in the precise identification of targeted prey. Current data on rorqual foraging in western Canadian waters have thus been limited to observations of prey species amenable to surface feeding, such as euphausiids and Pacific herring (Clupea pallasii), with no information on deeper alternative prey sources...
2023: PloS One
https://read.qxmd.com/read/36843970/a-peer-support-dietary-change-intervention-for-encouraging-adoption-and-maintenance-of-the-mediterranean-diet-in-a-non-mediterranean-population-team-med-lessons-learned-and-suggested-improvements
#33
JOURNAL ARTICLE
Katherine M Appleton, Claire T McEvoy, Christina Lloydwin, Sarah Moore, Patricia Salamanca-Gonzalez, Margaret E Cupples, Steven Hunter, Frank Kee, David R McCance, Ian S Young, Michelle C McKinley, Jayne V Woodside
Peer support interventions for dietary change may offer cost-effective alternatives to interventions led by health professionals. This process evaluation of a trial to encourage the adoption and maintenance of a Mediterranean diet in a Northern European population at high CVD risk (TEAM-MED) aimed to investigate the feasibility of implementing a group-based peer support intervention for dietary change, positive elements of the intervention and aspects that could be improved. Data on training and support for the peer supporters; intervention fidelity and acceptability; acceptability of data collection processes for the trial and reasons for withdrawal from the trial were considered...
2023: Journal of Nutritional Science
https://read.qxmd.com/read/36827271/how-to-estimate-body-condition-in-large-lizards-argentine-black-and-white-tegu-salvator-merianae-dum%C3%A3-ril-and-bibron-1839-as-a-case-study
#34
JOURNAL ARTICLE
Kelly R McCaffrey, Sergio A Balaguera-Reina, Bryan G Falk, Emily V Gati, Jenna M Cole, Frank J Mazzotti
Body condition is a measure of the health and fitness of an organism represented by available energy stores, typically fat. Direct measurements of fat are difficult to obtain non-invasively, thus body condition is usually estimated by calculating body condition indices (BCIs) using mass and length. The utility of BCIs is contingent on the relationship of BCIs and fat, thereby validation studies should be performed to select the best performing BCI before application in ecological investigations. We evaluated 11 BCIs in 883 Argentine black and white tegus (Salvator merianae) removed from their non-native range in South Florida, United States...
2023: PloS One
https://read.qxmd.com/read/36826930/carroll-s-three-stratum-3s-cognitive-ability-theory-at-30-years-impact-3s-chc-theory-clarification-structural-replication-and-cognitive-achievement-psychometric-network-analysis-extension
#35
JOURNAL ARTICLE
Kevin S McGrew
Carroll's treatise on the structure of human cognitive abilities is a milestone in psychometric intelligence research. Thirty years later, Carroll's work continues to influence research on intelligence theories and the development and interpretation of intelligence tests. A historical review of the relations between the 3S and CHC theories necessitates the recommendation that the theories of Cattell, Horn, and Carroll be reframed as a family of obliquely correlated CHC theories-not a single CHC theory. Next, a previously unpublished Carroll exploratory factor analysis of 46 cognitive and achievement tests is presented...
February 6, 2023: Journal of Intelligence
https://read.qxmd.com/read/36825676/nickel-catalyzed-sodium-hypophosphite-participated-direct-hydrophosphonylation-of-alkyne-toward-h-phosphinates
#36
JOURNAL ARTICLE
Dang-Wei Qian, Jin Yang, Gang-Wei Wang, Shang-Dong Yang
The traditional methods for the synthesis of phosphinate esters use phosphorus trichloride (PCl3 ) as the phosphorous source, resulting in procedures that are often highly polluting and energy intensive. The search for an alternative approach that is both mild and environmentally friendly is a challenging, yet highly rewarding task in modern chemistry. Herein, we use an inorganic phosphorous-containing species, NaH2 PO2 , to serve as the source of phosphorous that participates directly in the nickel-catalyzed selective alkyne hydrophosphonylation reaction...
February 24, 2023: Journal of Organic Chemistry
https://read.qxmd.com/read/36713300/complementary-medicine-and-expressive-arts-therapy-adjuvant-for-recovery-following-neurosurgical-procedures
#37
JOURNAL ARTICLE
Ashley M Carter, Emma R Dioso, Bethsabe Romero, Christopher E Clinker, Brandon Lucke-Wold
Art as a way of healing is primordial in many cultures. Expressive Arts Therapy (ExAT) uses art, music, dance, and writing to help individuals navigate their healing journey. Patient self-expression as a mode of recovery has been observed in patients with Parkinson's disease, epilepsy, Amyotrophic Lateral Sclerosis (ALS) and cancer. Complementary medical approaches such as acupuncture and mindfulness have also demonstrated benefits in patients suffering from neurological injury. Complementary medicine and ExAT are not mainstream approaches following neurosurgical procedures...
2023: OBM integrative and complimentary medicine
https://read.qxmd.com/read/36692609/missed-opportunities-when-we-focus-only-on-risk-using-the-concerns-based-conversation-starter-to-identify-potential-prep-candidates
#38
JOURNAL ARTICLE
Megan Mueller Johnson, Noah Brooks, K Rivet Amico
Collection and use of self-reported HIV sexual risk-behaviors to identify pre-exposure prophylaxis (PrEP) candidates is common practice in PrEP providing and referral services. Critiques of this strategy highlight overreliance on self-report and contribution to ongoing PrEP stigma. As an alternative (or complimentary) approach, we evaluated a 5-item Concerns Based Conversation Starter (CBCS) that could be used to identify individuals who could benefit from PrEP. The CBCS was included in the 2019 cycle of the American Men's Internet Survey...
January 24, 2023: AIDS and Behavior
https://read.qxmd.com/read/36481807/crash-severity-analysis-and-risk-factors-identification-based-on-an-alternate-data-source-a-case-study-of-developing-country
#39
JOURNAL ARTICLE
Hanif Bhuiyan, Jinat Ara, Khan Md Hasib, Md Imran Hossain Sourav, Faria Benta Karim, Cecilia Sik-Lanyi, Guido Governatori, Andry Rakotonirainy, Shamsunnahar Yasmin
Road traffic injuries are one of the primary reasons for death, especially in developing countries like Bangladesh. Safety in land transport is one of the major concerns for road safety authorities and other policymakers. For this reason, contributory factors identification associated with crashes is necessary for reducing road crashes and ensuring transportation safety. This paper presents an analytical approach to identifying significant contributing factors of Bangladesh road crashes by evaluating the road crash data, considering three different severity levels (non-fetal, severe, and extremely severe)...
December 8, 2022: Scientific Reports
https://read.qxmd.com/read/36480678/the-effects-of-self-administered-acupressure-on-fatigue-in-nursing-students-a-single-blind-randomized-sham-controlled-study
#40
JOURNAL ARTICLE
Esra Cavusoglu, Meral Gun
CONTEXT: Intern nursing students are exposed to many stressors, such as preparing for theoretical courses, studying for exams, fearing that they may make mistakes in clinical practice, working under inappropriate conditions, fearing infection, and experiencing insomnia. The stressors in question can increase the students' level of fatigue. OBJECTIVE: The study intended to determine the effects of acupressure on nursing students' fatigue. DESIGN: The research team designed a prospective, two-arm (1:1), single-blinded, randomized controlled clinical trial...
December 9, 2022: Alternative Therapies in Health and Medicine
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