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https://www.readbyqxmd.com/read/28749297/ebstein-anomaly-in-the-tsushima-leopard-cat-prionailurus-bengalensis-euptilurus
#1
Shunsuke Shimamura, Yukihiro Shiota, Naoko Takagi, Tatsuya Habara, Shougo Hirata, Hitoshi Komai, Satoko Nishimura, Hiroyuki Tani, Terumasa Shimada
Ebstein anomaly is a rare congenital heart disease that has been described in domestic dogs, a meerkat, a pygmy goat, and a lion. An 11-mo-old Tsushima leopard cat presented to Osaka Prefecture University Veterinary Hospital for diagnosis and treatment of right-sided congestive heart failure. Echocardiography showed a dilated right atrium and ventricle with an enlarged tricuspid valve annulus and apical displacement of the tricuspid valve leaflets. The cat was diagnosed with Ebstein anomaly. To the best of our knowledge, this is the first report of this type of congenital heart disease in a Tsushima leopard cat...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28749177/sprint-trial-it-s-not-just-the-blood-pressure
#2
Gijs Fn Berkelmans, Frank Lj Visseren, Nicole Em Jaspers, Wilko Spiering, Yolanda van der Graaf, Jannick An Dorresteijn
Background The SPRINT trial showed a beneficial effect of systolic blood pressure treatment targets of 120 mmHg on cardiovascular risk compared to targets of 140 mmHg. However, differences in medication use, most importantly diuretics, are suggested as an alternative explanation. This post-hoc analysis aimed to determine whether the reduced event rate can be attributed to changes in systolic blood pressure (ΔSBP) . Methods Analyses were based on all 9361 participants of the SPRINT trial. ΔSBP was defined as the change between baseline and 6-month follow-up systolic blood pressure...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28749055/a-failure-to-be-candid
#3
Jennifer McGuirl
I was a second-year neonatal-perinatal fellow in a meeting between other members of the neonatal intensive care team and parents who had just received devastating news about their planned-for and highly desired baby, born after what had been an uncomplicated pregnancy. At home, a little sister was waiting to meet her new brother. These conversations are never easy, but this one I found particularly disturbing. John had been born at term via emergency cesarean section after his mother, Muriel, had come for a routine obstetrical visit and reported decreased fetal movement...
July 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28748892/clinical-profile-of-geriatric-acute-kidney-injury-in-a-tertiary-care-center-from-south-india
#4
Eshwarappa Mahesh, Praveen Nallamuthu, Mahesh Kumar, Parampalli Rakesh Madhyastha, Gurudev Konanna
The incidence of acute kidney injury (AKI) is high in the elderly, who comprise an ever-growing segment of the population. Elderly patients pose a different set of diagnostic and therapeutic challenge owing to their associated comorbidities. AKI in the elderly is associated with an increased risk of mortality, morbidity, prolonged length of stay, and progression to chronic kidney disease. Data regarding the clinical profile of AKI in the elderly from the South Indian population are limited. Hence, we present this analysis of the etiological and prognostic factors associated with AKI in elderly population from South India...
July 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28748885/cardiac-status-in-children-with-acute-poststreptococcal-glomerulonephritis
#5
Tushar Idhate, Syed Ahmed Zaki, Preeti Shanbag
Acute poststreptococcal glomerulonephritis (PSGN) is the most common type of glomerulonephritis seen in children. It can affect multiple organs with heart being frequently involved. Yet, there are very few studies on cardiac status in children with PSGN and hence this study was conducted. All consecutive children from 1 month to 12 years of age, admitted over a two-year period with a diagnosis of PSGN, were included in the study. An electrocardiogram (ECG) and two-dimensional echocardiogram were performed in all patients on admission and repeated at six and 12 weeks, if abnormal...
July 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28748877/vitamin-d-levels-and-other-biochemical-parameters-of-mineral-bone-disorders-and-their-association-with-diastolic-dysfunction-and-left-ventricular-mass-in-young-nondiabetic-adult-patients-with-chronic-kidney-disease
#6
Satyendra Kumar Sonkar, Mohit Bhutani, Gyanendra Kumar Sonkar, Sant Kumar Pandey, Sharad Chandra, Vivek Bhosale
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients with end-stage renal disease. Chronic kidney disease (CKD)-associated cardiovascular mortality is more prevalent in those with diastolic heart failure and is an early predictor, while increased left ventricular mass (LVM) is a strong independent risk factor. Hypovitaminosis D is extensively being studied as a nontraditional risk factor for CVD. The aim of the present study is to look at the association of Vitamin D and other parameters of mineral bone disorder (MBD) with diastolic dysfunction and LVM in nondiabetic young adult patients with CKD...
July 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28748840/cardiovascular-involvement-in-severe-malaria-a-prospective-study-in-ranchi-jharkhand
#7
Hemant Narayan Ray, Darshit Doshi, Appu Rajan, Amit K Singh, S B Singh, M K Das
BACKGROUND & OBJECTIVES: Malaria is considered as the most important parasitic disease of humans, causing seri- ous illness that can be fatal, if not diagnosed and treated immediately. It is a multisystem disorder affecting nearly every system of the body. The aim of the present study was to evaluate the involvement of cardiovascular system in severe malaria using non-invasive methods. METHODS: This prospective study was conducted on patients of severe malaria who were admitted between June and November 2015 in the Department of Medicine, Rajendra Institute of Medical Sciences and Hospital, Ranchi, Jharkhand, India...
April 2017: Journal of Vector Borne Diseases
https://www.readbyqxmd.com/read/28748720/blunting-of-cardioprotective-actions-of-estrogen-in-female-rodent-heart-linked-to-altered-expression-of-cardiac-tissue-chymase-and-ace2
#8
Jacqueline S da Silva, Daniele Gabriel-Costa, Hao Wang, Sarfaraz Ahmad, Xuming Sun, Jasmina Varagic, Roberto T Sudo, Carlos M Ferrario, Louis J Dell Italia, Gisele-Zapata Sudo, Leanne Groban
BACKGROUND: Diastolic dysfunction develops in response to hypertension and estrogen (E2) loss and is a forerunner to heart failure (HF) in women. The cardiac renin-angiotensin system (RAS) contributes to diastolic dysfunction, but its role with respect to E2 and blood pressure remain unclear. METHODS: We compared the effects of ovariectomy (OVX) or sham surgery on the cardiac RAS, left ventricular (LV) structure/function, and systemic/intracardiac pressures of spontaneously hypertensive rats (SHRs: n = 6 intact and 6 OVX) and age-matched Wistar-Kyoto (WKY: n = 5 intact and 4 OVX) controls...
July 2017: Journal of the Renin-angiotensin-aldosterone System: JRAAS
https://www.readbyqxmd.com/read/28748266/treatment-of-chronic-heart-failure-in-germany-a-retrospective-database-study
#9
Stefan Störk, Renate Handrock, Josephine Jacob, Jochen Walker, Frederico Calado, Raquel Lahoz, Stephan Hupfer, Sven Klebs
BACKGROUND: Adherence to treatment guidelines affects outcomes in patients with chronic heart failure (HF). We investigated patient pathways and treatment patterns for HF in Germany. METHODS: This retrospective study used anonymous healthcare claims data from the German Health Risk Institute on individuals with statutory health insurance. Patients with uninterrupted data from 1 January 2009 to 31 December 2013 or death (whichever occurred first), and ≥2 recorded HF-related diagnoses in 2011, were included...
July 26, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28748265/epidemiology-of-heart-failure-in-germany-a-retrospective-database-study
#10
Stefan Störk, Renate Handrock, Josephine Jacob, Jochen Walker, Frederico Calado, Raquel Lahoz, Stephan Hupfer, Sven Klebs
BACKGROUND: Chronic heart failure (HF) is associated with significant healthcare expenditure, morbidity, and mortality. This study investigated the epidemiology of HF in Germany. METHODS: This retrospective study used anonymous healthcare claims data from the German Health Risk Institute on individuals with statutory health insurance. Patients with uninterrupted data from 1 January 2009 to 31 December 2013 or death (whichever occurred first), and ≥2 recorded HF-related diagnoses in 2011, were included...
July 26, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28748151/mesenchymal-stromal-cell-therapy-as-treatment-for-ischemic-heart-failure-the-msc-hf-study
#11
EDITORIAL
Enca Martin-Rendon, Mariann Gyöngyösi
No abstract text is available yet for this article.
June 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/28748119/uric-acid-in-the-pathogenesis-of-metabolic-renal-and-cardiovascular-diseases-a-review
#12
REVIEW
Usama A A Sharaf El Din, Mona M Salem, Dina O Abdulazim
The association between uric acid (UA) on one side and systemic hypertension (Htn), dyslipidemia, glucose intolerance, overweight, fatty liver, renal disease and cardiovascular disease (CVD) on the other side is well recognized. However, the causal relationship between UA and these different clinical problems is still debatable. The recent years have witnessed hundreds of experimental and clinical trials that favored the opinion that UA is a probable player in the pathogenesis of these disease entities. These studies disclosed the strong association between hyperuricemia and metabolic syndrome (MS), obesity, Htn, type 2 diabetes mellitus (DM), non-alcoholic fatty liver disease, hypertriglyceridemia, acute kidney injury, chronic kidney disease (CKD), coronary heart disease (CHD), heart failure and increased mortality among cardiac and CKD patients...
September 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/28747842/combined-application-of-extracorporeal-membrane-oxygenation-and-an-artificial-pacemaker-in-fulminant-myocarditis-in-a-child
#13
Sheng Ye, Lvchan Zhu, Botao Ning, Chenmei Zhang
Fulminant myocarditis is severe and aggressive, but it is self-limited and usually has a favorable prognosis if the patients can survive the acute phase. When drug treatment is not effective, extracorporeal membrane oxygenation technology should be applied to support cardiopulmonary function. Extracorporeal membrane oxygenation can simultaneously support function of the left ventricle, right ventricle, and lungs, and provide stable blood circulation for patients with heart and respiratory failure, which allows sufficient time for the cardiopulmonary system to recover...
June 2017: Türk Pediatri Arşivi
https://www.readbyqxmd.com/read/28747516/redundant-and-diverse-intranodal-pacemakers-and-conduction-pathways-protect-the-human-sinoatrial-node-from-failure
#14
Ning Li, Brian J Hansen, Thomas A Csepe, Jichao Zhao, Anthony J Ignozzi, Lidiya V Sul, Stanislav O Zakharkin, Anuradha Kalyanasundaram, Jonathan P Davis, Brandon J Biesiadecki, Ahmet Kilic, Paul M L Janssen, Peter J Mohler, Raul Weiss, John D Hummel, Vadim V Fedorov
The human sinoatrial node (SAN) efficiently maintains heart rhythm even under adverse conditions. However, the specific mechanisms involved in the human SAN's ability to prevent rhythm failure, also referred to as its robustness, are unknown. Challenges exist because the three-dimensional (3D) intramural structure of the human SAN differs from well-studied animal models, and clinical electrode recordings are limited to only surface atrial activation. Hence, to innovate the translational study of human SAN structural and functional robustness, we integrated intramural optical mapping, 3D histology reconstruction, and molecular mapping of the ex vivo human heart...
July 26, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28747039/prior-beta-blockers-use-is-independently-associated-with-increased-inpatient-mortality-in-patients-presenting-with-acute-myocardial-infarction
#15
Yan Zhou, Suzhen Chen, Xiang Zhu, Junhong Gui, Khalid Abusaada
BACKGROUND: Beta blockers (BBs) are recommended for patients presenting with acute myocardial infarction. However, the effects of prior BBs use on inpatient mortality in patients presenting with acute myocardial infarction (AMI) are unknown. METHODS: This was a retrospective cohort study of patients presenting with AMI in Florida Hospital Orlando from January 1, 2013 to December 31, 2014. Data were collected prospectively, as part of the Acute Coronary Treatment and Intervention Outcomes Network (ACTION) Registry...
September 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28747036/long-term-outcome-of-nonobstructive-versus-obstructive-hypertrophic-cardiomyopathy-a-systematic-review-and-meta-analysis
#16
Francesco Pelliccia, Vincenzo Pasceri, Giuseppe Limongelli, Camillo Autore, Cristina Basso, Domenico Corrado, Massimo Imazio, Claudio Rapezzi, Gianfranco Sinagra, Giuseppe Mercuro
BACKGROUND: Prognosis of hypertrophic cardiomyopathy (HCM) is particularly heterogeneous. Patients with nonobstructive HCM (NOCM) are thought to be at relatively low-risk as compared with obstructive HCM (HOCM) with no need of major treatment options. However, available evidence of NOCM comes mainly from tertiary centers where a referral bias is likely to occur. Aim of this study was to perform a systematic review and meta-analysis of the published literature on hypertrophic cardiomyopathy (HCM) in order to outline differences in presenting features and long-term outcome between NOCM and HOCM...
September 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28747035/elevated-circulating-il-32-presents-a-poor-prognostic-outcome-in-patients-with-heart-failure-after-myocardial-infarction
#17
Wanling Xuan, Weixing Huang, Ruijie Wang, Chang Chen, Yequn Chen, Yan Wang, Xuerui Tan
BACKGROUND: Interleukin-32 (IL-32) is a newly discovered proinflammatory cytokine. However, there are limited data regarding IL-32 as a biomarker for heart failure (HF). In this study, we assessed the prognostic value of IL-32 in patients with chronic HF after myocardial infarction (MI). METHODS AND RESULTS: Over a period of 1.8years, we prospectively enrolled 100 patients with chronic HF after MI. IL-32, NT-proBNP, Matrix metallopeptidase 9 (MMP-9), procollagen type I (PI) and type III (PIII) were measured at baseline...
September 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28747034/impact-of-peak-provoked-left-ventricular-outflow-tract-gradients-on-clinical-outcomes-in-hypertrophic-cardiomyopathy
#18
Dai-Yin Lu, Bereketeab Hailesealassie, Ioannis Ventoulis, Hongyun Liu, Hsin-Yueh Liang, Alexandra Nowbar, Iraklis Pozios, Marco Canepa, Kenneth Cresswell, Hong-Chang Luo, M Roselle Abraham, Theodore P Abraham
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is traditionally classified based on a left ventricular outflow tract (LVOT) pressure gradient of 30mmHg at rest or with provocation. There are no data on whether 30mmHg is the most informative cut-off value and whether provoked gradients offer any information regarding outcomes. METHODS: Resting and provoked peak LVOT pressure gradients were measured by Doppler echocardiography in patients fulfilling guidelines criteria for HCM...
September 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28747031/role-of-triggers-and-substrate-in-heart-failure-based-atrial-fibrillation-is-pulmonary-vein-isolation-still-the-cornerstone-of-atrial-fibrillation-therapy
#19
EDITORIAL
Reza Wakili, Dobromir Dobrev
No abstract text is available yet for this article.
September 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28747024/clinical-profile-and-outcomes-in-octogenarians-with-atrial-fibrillation-a-community-based-study-in-a-specific-european-health-care-area
#20
Moisés Rodríguez-Mañero, Estrella López-Pardo, Alberto Cordero, Omar Kredieh, María Pereira-Vazquez, Jose-Luis Martínez-Sande, Alvaro Martínez-Gomez, Carlos Peña-Gil, José Novo-Platas, Javier García-Seara, Pilar Mazón, Ricardo Laje, Isabel Moscoso, Alfonso Varela-Román, Jose María García-Acuña, José Ramón González-Juanatey
BACKGROUND: Age increases risk of stroke and bleeding. Clinical trial data have had relatively low proportions of elderly subjects. We sought to study a Spanish population of octogenarians with atrial fibrillation (AF) by combining different sources of electronic clinical records from an area where all medical centres utilized electronic health record systems. METHODS: Data was derived from the Galician Healthcare Service information system. RESULTS: From 383,000 subjects, AF was coded in 7990 (2...
September 15, 2017: International Journal of Cardiology
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