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https://www.readbyqxmd.com/read/28739517/novel-use-of-the-leksell-gamma-frame-for-stereotactic-biopsy-of-posterior-fossa-lesions-technical-note
#1
Shiro Horisawa, Hiroshi Nakano, Takakzu Kawamata, Takaomi Taira
BACKGROUND: Stereotactic transcerebellar biopsies of brainstem tumors have often been reported. The Leksell frame or Cosman-Roberts-Wells frame is often used in transcerebellar approaches. However, to access lesions via the cerebellum, these frames should be secured as inferiorly on the cranium as possible, which can require exaggerated neck flexion and limit the flexible trajectory to the target. To overcome these disadvantages, we have devised a new way to use the Leksell frame for transcerebellar approaches...
July 21, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28733722/non-specific-chronic-low-back-pain-differences-in-spinal-kinematics-in-subgroups-during-functional-tasks
#2
Rebecca Hemming, Liba Sheeran, Robert van Deursen, Valerie Sparkes
PURPOSE: A multidimensional classification approach suggests that motor control impairment subgroups exist in non-specific chronic low back pain (NSCLBP). Differences in sitting lumbar posture have been identified between two such subgroups [flexion pattern (FP) and active extension pattern (AEP)] and healthy individuals; however, functional spinal movement has not been explored. This study will evaluate whether NSCLBP subgroups exhibit regional spinal kinematic differences, compared to healthy individuals, during functional tasks...
July 21, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28730167/the-clinical-characteristics-of-patients-with-chronic-idiopathic-anal-pain
#3
Weiming Mao, Xiujun Liao, Wenjing Wu, Yanyan Yu, Guangen Yang
The aim of this study was to investigate the clinical characteristics, treatment outcomes and psychological distress in patients with chronic idiopathic anal pain. The study was conducted on patients referred to Hangzhou Third Hospital for chronic anal pain from January, 2010 to December, 2014. Patient demographics, clinical history, anorectal physiology, and radiological imaging data were recorded for all patients. The treatment outcome was noted for patients treated and followed up for more than 6 month at the present unit...
2017: Open Medicine (Warsaw, Poland)
https://www.readbyqxmd.com/read/28717053/pure-autonomic-failure
#4
REVIEW
Thomas P Brown
Pure autonomic failure is a degenerative disorder of the peripheral autonomic nervous system. Patients experience symptomatic hypotension that requires them to sit, squat or lie down to prevent syncope. It is associated with characteristic histopathological findings, resulting in neuronal cytoplasmic inclusions in the peripheral autonomic nerves. These lesions are responsible for defects in the synthesis and release of norepinephrine from sympathetic nerve terminals, resulting in significant hypotension. Patients with autonomic failure also have exaggerated blood pressure responses to common stimuli such as food or fluid intake, heat, exercise and medications...
July 17, 2017: Practical Neurology
https://www.readbyqxmd.com/read/28685312/affected-ear-up-120%C3%A2-maneuver-for-treatment-of-lateral-semicircular-canal-benign-paroxysmal-positional-vertigo
#5
Hiroaki Ichijo
Although several researchers have tried various canalith repositioning procedures for lateral canalolithiasis, a standard treatment has not been established. We adopt 120° rotation, which is anatomically appropriate because the principle of cure may be the fixing of pathological debris to the dark cells of the utricle. The aims of this study were to clarify the efficacy rate of the affected-ear-up 120° maneuver and to elucidate the appearance rate of lying-down nystagmus in patients with lateral canalolithiasis...
July 6, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28663380/bone-microvascular-flow-differs-from-skin-microvascular-flow-in-response-to-head-down-tilt
#6
Michelle Howden, Jamila H Siamwala, Alan R Hargens
Loss of hydrostatic pressures in microgravity may alter skin and bone microvascular flows in the lower extremities and may potentially reduce wound healing and bone fracture repair. The purpose of this study was to determine the rate at which skin and bone microvascular flows respond to head down tilt (HDT). We hypothesized that microvascular flows in tibial bone and overlying skin would increase at different rates during HDT. Tibial bone and skin microvascular flows were measured simultaneously using photoplethysmography (PPG) in a total of 17 subjects during sitting (control posture), supine, 6° HDT, 15° HDT, and 30° HDT postures in random order...
June 29, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28642479/a-genetically-enhanced-sterile-insect-technique-against-the-fruit-fly-bactrocera-dorsalis-hendel-by-feeding-adult-double-stranded-rnas
#7
Muhammad Waqar Ali, Wenping Zheng, Summar Sohail, Qingmei Li, Weiwei Zheng, Hongyu Zhang
RNAi based sterile insect technique (SIT) is an authentic insect management approach but requires proper target genes. During this study, spermless males were developed by interfering with germ cell differentiation and azoospermia related genes. Data demonstrates significant reductions in the target genes expressions (boul, zpg, dsx (M) , fzo and gas8) after oral dsRNAs administration. Knock down of target genes significantly affected the reproductive ability of males and reduced egg-hatching as compared to the control group...
June 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28641680/ophthalmological-evaluation-of-integrated-resistance-and-aerobic-training-during-70-day-bed-rest
#8
Giovanni Taibbi, Ronita L Cromwell, Susana B Zanello, Patrice O Yarbough, Robert J Ploutz-Snyder, Bernard F Godley, Gianmarco Vizzeri
INTRODUCTION: We evaluated ophthalmic changes in healthy individuals who underwent integrated resistance and aerobic training (iRAT) during 70-d 6° head-down tilt (HDT) bed rest (BR). METHODS: Participants were selected using NASA standard screening procedures. Standardized NASA BR conditions were implemented. Subjects were randomly assigned to the iRAT protocol or no exercise during HDTBR. Weekly ophthalmic examinations were performed in the sitting (pre/post-BR only) and HDT (BR only) positions...
July 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28635194/volitional-rehabilitative-assessments-in-patients-admitted-in-a-post-intensive-care-step-down-unit-a-feasibility-study
#9
Mara Paneroni, Francesco D' Abrosca, Georges Fokom, Laura Comini, Michele Vitacca
A high variability in functional tests and activities used during the pulmonary rehabilitation has been observed in post-intensive care unit (ICU) patients, and the best battery of tests to adopt has not been described yet. We tested in patients admitted in a post-ICU Step Down Unit the ability to perform the more frequent functional volitional tests. The relations of each single volitional test with general disability and dyspnea at discharge were also evaluated. Ten volitional tests including: bedside spirometry test (ST: FEV1%, FVC%), maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP), Peak Expiratory Flow during Cough (PCEF), Quadriceps Muscle Strength (QMS), latissimus Dorsi and teres Major Strength (DMS), Brachial biceps Muscle Strength (BMS), effort tolerance measured by sit-to-stand test, Takahashi test and 6-Min Walking Test (6MWT), were evaluated in post-ICU patients at entry and discharge from in-hospital rehabilitation...
May 18, 2017: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/28603280/dust-mite-allergen-specific-immunotherapy-increases-il4-dna-methylation-and-induces-der-p-specific-t-cell-tolerance-in-children-with-allergic-asthma
#10
Chuang-Ming Wang, Chia-Bin Chang, Michael Wy Chan, Zhi-Hong Wen, Shu-Fen Wu
Allergen-specific immunotherapy (allergen-SIT) is a highly effective treatment for children with allergic asthma (AA), an immune-mediated chronic disease leading to bronchial muscle hypertrophy and airway obstruction in response to specific allergens. T helper cells and secreted cytokines play important roles in the pathogenesis of asthma, and epigenetic modulation controls genes important for T cell development and cytokine expression. This study evaluated T helper cell-secreted cytokines and DNA methylation patterns in children treated with Dermatophagoides pteronyssinus (Der p) allergen-SIT...
June 26, 2017: Cellular & Molecular Immunology
https://www.readbyqxmd.com/read/28572078/the-effect-of-core-stabilization-exercise-on-the-kinematics-and-joint-coordination-of-the-lumbar-spine-and-hip-during-sit-to-stand-and-stand-to-sit-in-patients-with-chronic-nonspecific-low-back-pain-coscious-study-protocol-for-a-randomized-double-blind-controlled
#11
Mohammad Reza Pourahmadi, Ismail Ebrahimi Takamjani, Shapour Jaberzadeh, Javad Sarrafzadeh, Mohammad Ali Sanjari, Holakoo Mohsenifar, Rasool Bagheri, Morteza Taghipour
BACKGROUND: Chronic nonspecific low back pain (CNLBP) is among the most prevalent health problems. Lumbar spine and hips kinematics and coordination can be affected in CNLBP. The effects of exercises on the kinematics and coordination of lumbar spine and hips during sit-to-stand (STS) and its reverse have not been evaluated. OBJECTIVE: The aim of this study is to investigate the effect of core stabilization exercise on the kinematics and joint coordination of the lumbar spine and hip during STS and its reverse in CNLBP patients...
June 1, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28558835/a-muscle-driven-approach-to-restore-stepping-with-an-exoskeleton-for-individuals-with-paraplegia
#12
Sarah R Chang, Mark J Nandor, Lu Li, Rudi Kobetic, Kevin M Foglyano, John R Schnellenberger, Musa L Audu, Gilles Pinault, Roger D Quinn, Ronald J Triolo
BACKGROUND: Functional neuromuscular stimulation, lower limb orthosis, powered lower limb exoskeleton, and hybrid neuroprosthesis (HNP) technologies can restore stepping in individuals with paraplegia due to spinal cord injury (SCI). However, a self-contained muscle-driven controllable exoskeleton approach based on an implanted neural stimulator to restore walking has not been previously demonstrated, which could potentially result in system use outside the laboratory and viable for long term use or clinical testing...
May 30, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28553675/activityaware-an-app-for-real-time-daily-activity-level-monitoring-on-the-amulet-wrist-worn-device
#13
George Boateng, John A Batsis, Ryan Halter, David Kotz
Physical activity helps reduce the risk of cardiovascular disease, hypertension and obesity. The ability to monitor a person's daily activity level can inform self-management of physical activity and related interventions. For older adults with obesity, the importance of regular, physical activity is critical to reduce the risk of long-term disability. In this work, we present ActivityAware, an application on the Amulet wrist-worn device that measures daily activity levels (sedentary, moderate and vigorous) of individuals, continuously and in real-time...
March 2017: Proc IEEE Int Conf Pervasive Comput Commun Workshops
https://www.readbyqxmd.com/read/28539008/position-in-the-second-stage-of-labour-for-women-without-epidural-anaesthesia
#14
REVIEW
Janesh K Gupta, Akanksha Sood, G Justus Hofmeyr, Joshua P Vogel
BACKGROUND: For centuries, there has been controversy around whether being upright (sitting, birthing stools, chairs, squatting, kneeling) or lying down (lateral (Sim's) position, semi-recumbent, lithotomy position, Trendelenburg's position) have advantages for women giving birth to their babies. This is an update of a review previously published in 2012, 2004 and 1999. OBJECTIVES: To determine the possible benefits and risks of the use of different birth positions during the second stage of labour without epidural anaesthesia, on maternal, fetal, neonatal and caregiver outcomes...
May 25, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28535061/sitting-phase-monolayers-of-polymerizable-phospholipids-create-dimensional-molecular-scale-wetting-control-for-scalable-solution-based-patterning-of-layered-materials
#15
Shi Wah Choong, Shane R Russell, Jae Jin Bang, Justin K Patterson, Shelley A Claridge
The use of dimensionally ordered ligands on layered materials to direct local electronic structure and interactions with the environment promises to streamline integration into nanostructured electronic, optoelectronic, sensing, and nanofluidic interfaces. Substantial progress has been made in using ligands to control substrate electronic structure. Conversely, using the exposed face of the ligand layer to structure wetting and binding interactions, particularly with scalable solution- or spray-processed materials, remains a significant challenge...
June 7, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28526329/a-behaviour-change-intervention-to-reduce-sedentary-time-in-people-with-chronic-obstructive-pulmonary-disease-protocol-for-a-randomised-controlled-trial
#16
Sonia Wing Mei Cheng, Jennifer Alison, Sarah Dennis, Emmanuel Stamatakis, Lissa Spencer, Renae McNamara, Susan Sims, Zoe McKeough
INTRODUCTION: Replacing sedentary behaviour with light intensity physical activity (ie, activities classified as less than three metabolic equivalents, such as slow-paced walking) may be a more realistic strategy for reducing cardiometabolic risk in people with chronic obstructive pulmonary disease than only aiming to increase levels of moderate-vigorous intensity physical activity. Behaviour change interventions to reduce sedentary behaviour in people with chronic obstructive pulmonary disease have not yet been developed or tested...
July 2017: Journal of Physiotherapy
https://www.readbyqxmd.com/read/28495841/lower-body-negative-pressure-decreases-non-invasively-measured-intracranial-pressure-and-internal-jugular-vein-cross-sectional-area-during-head-down-tilt
#17
William Watkins, Alan R Hargens, Shannon Baird, Erika Marie Clary, Brandon R Macias
INTRODUCTION: Long-term space flight induces a near visual acuity change in approximately 50% of astronauts. In some crew members, postflight cerebrospinal fluid (CSF) opening pressures by lumbar puncture are as high as 20.9 mmHg who demonstrated optic disc edema. CSF communicates through the cochlear aqueduct to affect perilymphatic pressure and tympanic membrane motion. We hypothesized that 50 mmHg of lower-body negative pressure (LBNP) during 15° head-down tilt (HDT) would mitigate elevations in internal jugular vein cross-sectional area (IJV CSA) and intracranial pressure (ICP)...
May 11, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28494261/relationship-between-physical-performance-and-self-reported-function-in-healthy-individuals-across-the-lifespan
#18
Jennifer N Baldwin, Marnee J McKay, Claire E Hiller, Niamh Moloney, Elizabeth J Nightingale, Joshua Burns
BACKGROUND: Functional outcome measures in clinical trials of musculoskeletal conditions need to be meaningful to individuals. OBJECTIVES: To investigate the relationship between physical performance and self/proxy-reported function in 1000 healthy children and adults. DESIGN: Cross-sectional observational study (1000 Norms Project). METHODS: One thousand males and females aged 3-101 years, healthy by self-report and without major physical disability, were recruited...
May 2, 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/28473281/linear-and-nonlinear-analysis-of-postural-control-in-frailty-syndrome
#19
Verena de Vassimon-Barroso, Aparecida Maria Catai, Marcele Stephanie De Souza Buto, Alberto Porta, Anielle Cristhine De Medeiros Takahashi
BACKGROUND: Adaptive postural control can be impaired in the presence of frailty syndrome, given that this condition causes homeostatic dysregulation in physiological systems. OBJECTIVES: To compare the center of pressure (CoP) displacements of non-frail, pre-frail, and frail elderly subjects in the standing position before and after postural transition of sitting and rising from a chair, using linear and nonlinear methods. METHODS: Forty-two elderly subjects were divided into 3 groups: non-frail (n=15), pre-frail (n=15), and frail (n=12)...
April 9, 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28444348/how-physically-active-are-people-following-stroke-systematic-review-and-quantitative-synthesis
#20
Natalie A Fini, Anne E Holland, Jenny Keating, Jacinta Simek, Julie Bernhardt
Background: : Mobility limitations are common following stroke and frequently lead to poor participation in physical activity (PA). Purpose: : To describe PA across the various stages following stroke (acute, subacute and chronic). Data Sources: : Searches were conducted in five databases. Study Selection: : Eligible studies included participants with stroke whose PA was quantitatively measured for at least four hours in a single session...
April 21, 2017: Physical Therapy
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