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https://www.readbyqxmd.com/read/29679793/self-stigma-in-ptsd-prevalence-and-correlates
#1
Kelsey A Bonfils, Paul H Lysaker, Philip T Yanos, Alysia Siegel, Bethany L Leonhardt, Alison V James, Beth Brustuen, Brandi Luedtke, Louanne W Davis
Self-stigma is the internalization of negative societal stereotypes about those with mental illnesses. While self-stigma has been carefully characterized in severe mental disorders, like schizophrenia, the field has yet to examine the prevalence and correlates of self-stigma in post-traumatic stress disorder (PTSD). Thus, we assessed self-stigma in veterans diagnosed with PTSD and compared with veterans with schizophrenia. We further examined associations between PTSD, depressive symptoms and self-stigma in the PTSD sample...
April 3, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29679597/management-of-dyspnea-in-the-terminally-ill
#2
REVIEW
Lara Pisani, Nicholas S Hill, Angela Maria Grazia Pacilli, Massimiliano Polastri, Stefano Nava
The genesis of dyspnea involves the activation of several mechanisms that are mediated and perceived depending on previous experiences, values, emotions and beliefs. Breathlessness may become unbearable, especially in terminally ill patients, whether afflicted by respiratory, cardiac or cancer-related disorders, due to a final stage of a chronic process, an acute event or both. Compared to pain, palliation of dyspnea has received relatively little attention in clinical practice and the medical literature. This is particularly true when the breathlessness is associated with acute respiratory failure since most of the studies on pharmacological and non-pharmacological treatments of respiratory distress have excluded such patients...
April 18, 2018: Chest
https://www.readbyqxmd.com/read/29679531/the-association-of-early-postoperative-lactate-levels-with-morbidity-after-elective-major-abdominal-surgery
#3
Jelena Veličković, Ivan Palibrk, Biljana Miličić, Dejan Veličković, Bojan Jovanović, Goran Rakić, Milorad Petrović, Vesna Bumbaširević
Lactate levels are widely used as an indicator of outcome in critically ill patients. We investigated the prognostic value of postoperative lactate levels for postoperative complications (POC), mortality and length of hospital stay after elective major abdominal surgery. A total of 195 patients were prospectively evaluated. Lactate levels were assessed on admission to the intensive care unit (ICU) [L0], 4 hours (L4), 12 hours (L12), and 24 hours (L24) after the operation. Demographic and perioperative clinical data were collected...
April 21, 2018: Bosnian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/29679418/family-involvement-in-rehabilitation-coronary-artery-disease-patients-perspectives
#4
Sonja Tuomisto, Meeri Koivula, Päivi Åstedt-Kurki, Mika Helminen
AIMS AND OBJECTIVES: The aim of this paper is to describe CAD -patients' perceptions of family involvement in rehabilitation and the connection between background factors and family involvement. BACKGROUND: CAD-patients hospital stays can be very concise. Family members can support rehabilitation, but many challenges can emerge. There is a need to nurture patients and family members in an individual way and to recognize their concerns. More accurate patient education should be available for patients and their family members...
April 21, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29679264/technology-focused-family-interventions-in-pediatric-chronic-illness-a-systematic-review
#5
REVIEW
Kimberly S Canter, Jennifer Christofferson, Michele A Scialla, Anne E Kazak
This systematic review provides a synthesis of randomized-controlled trials of technology-focused family interventions for children with chronic illnesses and their families, focused on describing the current state of the literature and generating recommendations for future family systems work in the field of eHealth/mHealth. Twenty-three studies met inclusion criteria and were included in the systematic review. No identified studies featured an mHealth delivery modality. Relevant data were extracted and studies were assessed for quality...
April 20, 2018: Journal of Clinical Psychology in Medical Settings
https://www.readbyqxmd.com/read/29679192/the-disclosure-of-celebrity-major-depressive-disorder-diagnoses-in-hong-kong-its-effects-on-public-awareness-and-understanding-toward-the-illness
#6
Vivienne S Y Leung
This paper aims to examine consumer perception toward celebrity diagnoses of major depressive disorder (MDD) in Hong Kong and to provide insights into the effect of various factors on the persuasive effectiveness of MDD communication. A total of thirty-five interviews were conducted in April 2015. Interviewees in general are aware of celebrity MDD diagnoses, but they do not deem MDD as a threat to themselves. Hence, they are not motivated to learn more about the symptoms. Responses to celebrity MDD diagnoses are mixed...
April 21, 2018: Community Mental Health Journal
https://www.readbyqxmd.com/read/29679153/stigma-as-a-barrier-to-recognizing-personal-mental-illness-and-seeking-help-a-prospective-study-among-untreated-persons-with-mental-illness
#7
Georg Schomerus, Susanne Stolzenburg, Simone Freitag, Sven Speerforck, Deborah Janowitz, Sara Evans-Lacko, Holger Muehlan, Silke Schmidt
It is unclear to what extent failure to recognize symptoms as potential sign of a mental illness is impeding service use, and how stigmatizing attitudes interfere with this process. In a prospective study, we followed a community sample of 188 currently untreated persons with mental illness (predominantly depression) over 6 months. We examined how lack of knowledge, prejudice and discrimination impacted on self-identification as having a mental illness, perceived need, intention to seek help, and help-seeking, both with respect to primary care (visiting a general practitioner, GP) and specialist care (seeing a mental health professional, MHP)...
April 20, 2018: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/29679071/determinants-of-treatment-response-in-first-episode-psychosis-an-18-f-dopa-pet-study
#8
Sameer Jauhar, Mattia Veronese, Matthew M Nour, Maria Rogdaki, Pamela Hathway, Federico E Turkheimer, James Stone, Alice Egerton, Philip McGuire, Shitij Kapur, Oliver D Howes
Psychotic illnesses show variable responses to treatment. Determining the neurobiology underlying this is important for precision medicine and the development of better treatments. It has been proposed that dopaminergic differences underlie variation in response, with striatal dopamine synthesis capacity (DSC) elevated in responders and unaltered in non-responders. We therefore aimed to test this in a prospective cohort, with a nested case-control comparison. 40 volunteers (26 patients with first-episode psychosis and 14 controls) received an 18 F-DOPA Positron Emission Tomography scan to measure DSC (Kicer ) prior to antipsychotic treatment...
April 20, 2018: Molecular Psychiatry
https://www.readbyqxmd.com/read/29678993/qualitative-longitudinal-study-of-episodic-disability-experiences-of-older-women-living-with-hiv-in-ontario-canada
#9
Patricia Solomon, Kelly K O'Brien, Stephanie Nixon, Lori Letts, Larry Baxter, Nicole Gervais
OBJECTIVES: To examine the episodic disability experiences of older women living with HIV over time. DESIGN: Qualitative longitudinal study, conducting semistructured in-depth interviews on four occasions over a 20-month time frame. Inductive thematic analyses were conducted cross-sectionally and longitudinally. SETTING: Participants were recruited from HIV community organisations in Canada. PARTICIPANTS: 10 women aged 50 years or older living with HIV for more than 6 years...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678989/prescribing-and-deprescribing-antihypertensive-medication-in-older-people-by-dutch-general-practitioners-a-qualitative-study
#10
Tessa van Middelaar, Sophie D Ivens, Petra G van Peet, Rosalinde K E Poortvliet, Edo Richard, A Jeannette Pols, Eric P Moll van Charante
OBJECTIVES: To explore general practitioners' (GPs) routines and considerations on (de)prescribing antihypertensive medication (AHM) in older patients, their judgement on usability of the current guideline and needs for future support. DESIGN: Semistructured interviews. SETTING: Dutch general practice. PARTICIPANTS: Fifteen GPs were purposively sampled based on level of experience and practice characteristics until saturation was reached...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678973/involving-the-public-in-epidemiological-public-health-research-a-qualitative-study-of-public-and-stakeholder-involvement-in-evaluation-of-a-population-wide-natural-policy-experiment
#11
Rachel Anderson de Cuevas, Lotta Nylén, Bo Burström, Margaret Whitehead
BACKGROUND: Public involvement in research is considered good practice by European funders; however, evidence of its research impact is sparse, particularly in relation to large-scale epidemiological research. OBJECTIVES: To explore what difference public and stakeholder involvement made to the interpretation of findings from an evaluation of a natural policy experiment to influence the wider social determinants of health: 'Flexicurity'. SETTING: Stockholm County, Sweden...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678964/technology-enabled-examinations-of-cardiac-rhythm-optic-nerve-oral-health-tympanic-membrane-gait-and-coordination-evaluated-jointly-with-routine-health-screenings-an-observational-study-at-the-2015-kumbh-mela-in-india
#12
Pratik Shah, Gregory Yauney, Otkrist Gupta, Vincent Patalano Ii, Mrinal Mohit, Rikin Merchant, S V Subramanian
OBJECTIVES: Technology-enabled non-invasive diagnostic screening (TES) using smartphones and other point-of-care medical devices was evaluated in conjunction with conventional routine health screenings for the primary care screening of patients. DESIGN: Dental conditions, cardiac ECG arrhythmias, tympanic membrane disorders, blood oxygenation levels, optic nerve disorders and neurological fitness were evaluated using FDA-approved advanced smartphone powered technologies...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678913/long-term-survival-and-thermal-death-kinetics-of-enterohemorrhagic-escherichia-coli-serogroups-o26-o103-o111-and-o157-in-wheat-flour
#13
Fereidoun Forghani, Meghan den Bakker, Alexandra N Futral, Francisco Diez-Gonzalez
Wheat flour has been associated with outbreaks of enterohemorrhagic Escherichia coli (EHEC), but little is known on EHEC's survival during storage and thermal processing. The objectives of this study were to determine long-term viability and thermal inactivation kinetics of serogroups O26, O103, O111 and O157. Wheat flour samples were inoculated with a cocktail of five strains of a single serogroup and stored at 23 and 35 °C. Inoculated samples were heated at 55, 60, 65 and 70 °C. Viability was determined by plate counting...
April 20, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29678770/self-reported-pain-in-patients-with-schizophrenia-results-from-the-national-first-step-face-sz-cohort
#14
Guillaume Fond, Laurent Boyer, Meja Andrianarisoa, Ophelia Godin, Ewa Bulzacka, Fabrice Berna, Lore Brunel, Nathalie Coulon, Bruno Aouizerate, Delphine Capdevielle, Isabelle Chereau, Thierry D'amato, Hélène Denizot, Caroline Dubertret, Julien Dubreucq, Catherine Faget, Sylvain Leignier, Jasmina Mallet, David Misdrahi, Romain Rey, Christophe Lancon, Christine Passerieux, Aurélie Schandrin, Mathieu Urbach, Pierre Vidailhet, Marion Leboyer, Franck Schurhoff, Pierre-Michel Llorca, M Andrianarisoa, B Aouizerate, F Berna, O Blanc, L Brunel, E Bulzacka, D Capdevielle, I Chereau-Boudet, G Chesnoy-Servanin, Danion Jm, T D'Amato, A Deloge, C Delorme, H Denizot, J M Dorey, C Dubertret, J Dubreucq, C Faget, C Fluttaz, G Fond, S Fonteneau, F Gabayet, E Giraud-Baro, R M Honciuc, D Lacelle, C Lançon, H Laouamri, M Leboyer, T Le Gloahec, Y Le Strat, Llorca, J Mallet, E Metairie, D Misdrahi, I Offerlin-Meyer, C Passerieux, P Peri, S Pires, C Portalier, R Rey, C Roman, M Sebilleau, A Schandrin, F Schurhoff, A Tessier, Tronche Am, M Urbach, F Vaillant, A Vehier, P Vidailhet, E Vilà, H Yazbek, A Zinetti-Bertschy
INTRODUCTION: Little is known about perception of physical pain in schizophrenia (SZ). Some studies have suggested that patients with SZ may have an increased pain threshold, while others have suggested that patients with SZ may suffer from undetected and untreated high physical pain levels. The objectives of this study were (i) to investigate the prevalence of self-reported physical pain in stabilized SZ subjects, and (ii) to determine whether physical pain was associated with psychiatric characteristics and somatic comorbidities (iii) to determine whether antidepressants and benzodiazepine administration were associated with lower self-reported pain...
April 17, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29678735/recent-developments-of-nanotherapeutics-for-targeted-and-long-acting-combination-hiv-chemotherapy
#15
REVIEW
Yu Gao, John C Kraft, Danni Yu, Rodney J Y Ho
Combination antiretroviral therapy (cART) given orally has transformed HIV from a terminal illness to a manageable chronic disease. Yet despite the recent development of newer and more potent drugs for cART and suppression of virus in blood to undetectable levels, residual virus remains in tissues. Upon stopping cART, virus rebounds and progresses to AIDS. Current oral cART regimens have several drawbacks including (1) challenges in patient adherence due to pill fatigue or side-effects, (2) the requirement of life-long daily drug intake, and (3) limited penetration and retention in cells within lymph nodes...
April 17, 2018: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/29678491/polycystic-ovary-syndrome-pcos-an-inflammatory-systemic-lifestyle-endocrinopathy
#16
REVIEW
Seema Patel
Polycystic ovary syndrome (PCOS) is an endocrine disorder, afflicting females of reproductive age. This syndrome leads to infertility, apart from a gamut of other metabolic co-morbidities such as insulin resistance, obesity, cardiovascular problems, including a litany of other health issues. PCOS is a polygenic, polyfactorial, systemic, inflammatory, dysregulated steroid state, autoimmune disease, manifesting largely due to lifestyle errors. The advent of biochemical tests and ultrasound scanning has enabled the detection of PCOS in the affected females...
April 17, 2018: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29678434/continuous-versus-bolus-furosemide-in-the-critically-ill-more-questions-than-answers
#17
EDITORIAL
Youn-Hoa Jung, Jochen Steppan, Lee A Goeddel
No abstract text is available yet for this article.
February 22, 2018: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29678361/chikungunya-report-from-the-task-force-on-tropical-diseases-by-the-world-federation-of-societies-of-intensive-and-critical-care-medicine
#18
Pravin Amin, Gisele Sampaio Silva, Jorge Hidalgo, Juan Ignacio Silesky Jiménez, Dilip R Karnad, Guy A Richards
Chikungunya is an arbovirus that is transmitted by the Aedes mosquito causing a febrile illness with periodic outbreaks in large parts of the world. In the last decade it has become a public health concern in a host of countries and has affected international tourists. In the vast majority of cases Chikungunya presents as an acute febrile illness, associated with rash, headache, myalgia and debilitating arthralgia or even polyarthritis. A small proportion of patients present atypically with nervous, ocular, renal, myocardial, respiratory and renal system involvement and may require ICU management...
April 7, 2018: Journal of Critical Care
https://www.readbyqxmd.com/read/29678324/time-series-study-of-weather-water-quality-and-acute-gastroenteritis-at-water-safety-plan-implementation-sites-in-france-and-spain
#19
Karen E Setty, Jerome Enault, Jean-Francois Loret, Claudia Puigdomenech Serra, Jordi Martin-Alonso, Jamie Bartram
Water Safety Plans (WSPs), recommended by the World Health Organization since 2004, can help drinking water suppliers to proactively identify potential risks and implement preventive barriers that improve safety. Few studies have investigated long-term impacts of WSPs, such as changes in drinking water quality or public health; however, some evidence from high-income countries associates WSP implementation with a reduction in diarrheal disease. To validate the previously observed linkages between WSPs and health outcomes, this time series study examined site-specific relationships between water-related exposures and acute gastroenteritis rates at three locations in France and Spain, including the role of WSP status...
April 6, 2018: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/29678276/a-feasibility-study-of-a-physiotherapy-led-motivational-programme-to-increase-physical-activity-and-improve-cardiometabolic-risk-in-people-with-major-mental-illness
#20
Alice Waugh, Niall Crumlish, Eric Kelleher, Cuisle Forde, Julie Broderick
No abstract text is available yet for this article.
March 13, 2018: General Hospital Psychiatry
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