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https://www.readbyqxmd.com/read/29668131/-severe-hypoxemic-respiratory-failure-caused-by-pneumocystis-jirovecii-in-a-late-kidney-transplant-recipient
#1
John Fredy Nieto-Ríos, Mónica Zuluaga-Quintero, Arbey Aristizábal-Alzate, Catalina Ocampo-Kohn, Lina María Serna-Higuita, Isabel Cristina Ramírez-Sánchez, Gustavo Adolfo Zuluaga-Valencia
Pneumonia caused by Pneumocystis jirovecii is an uncommon infection in kidney transplant patients that can have an acute and rapid progression to respiratory failure and death. The period of greatest risk occurs in the first six months after the transplant, and it relates to the high doses of immunosuppression drugs required by patients. However, it may occur late, associated with the suspension of prophylaxis with trimethoprim-sulfamethoxazole.We present two cases of renal transplant patients who had severe hypoxemic respiratory failure due to P...
March 15, 2018: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29668129/-tuberculosis-in-the-era-of-anti-tnf-alpha-therapy-why-does-the-risk-still-exist
#2
John-Leonardo Torres-Castiblanco, Jorge Alberto Carrillo, Daniel Hincapié-Urrego, Adriana Rojas-Villarraga
Rheumatoid arthritis is an autoimmune systemic disease characterized mainly by inflammatory compromise of diarthrodial joints. Multiple drug therapies have been developed to control the activity of rheumatoid arthritis, among them, the first line of disease-modifying antirheumatic drugs (DMARD), and novel drug therapies such as the anti-TNF alpha therapy, with satisfactory clinical outcomes.Despite this positive fact, the use of this therapy implies the risk of producing negative effects due to its mechanism of action, which has been associated with multiple infections, especially tuberculosis, making it necessary to use screen tests before resorting to this kind of drugs...
March 15, 2018: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29668128/tuberculosis-associated-with-tumor-necrosis-factor-%C3%AE-antagonists-case-description-and-analysis-of-reported-cases-in-colombia
#3
Leandro Galvis, Ángel Y Sánchez, Leonardo F Jurado, Martha I Murcia
Tumor necrosis factor-α (TNF-α) is an important fundamental cytokine during the immune response against cancer and infections such as tuberculosis. This molecule also plays a key pathogenic role in complex and difficult-to-treat diseases such as rheumatoid arthritis, ankylosing spondylitis, Crohn's disease, psoriasis and ulcerative colitis. The treatment of these diseases frequently needs TNF-α antagonists, which has been related to an increased risk of developing tuberculosis, mycoses, and other severe infections...
March 15, 2018: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29668068/epidemiology-risk-factors-and-outcomes-of-invasive-aspergillosis-in-solid-organ-transplant-recipients-in-the-swiss-transplant-cohort-study
#4
D Neofytos, O Chatzis, D Nasioudis, E Boely Janke, T Doco Lecompte, C Garzoni, C Berger, A Cussini, K Boggian, N Khanna, O Manuel, N J Mueller, C van Delden
BACKGROUND: There is lack of recent multicenter epidemiological data on invasive aspergillosis (IA) among solid organ transplant recipient (SOTr) in the mold-acting antifungal era. We describe the epidemiology and outcomes of IA in a contemporary cohort of SOTr using the Swiss Transplant Cohort Study. METHODS: All consecutive SOTr with proven or probable IA between 01.05.2008 and 31.12.2014 were included. A case-control study to identify IA predictors was performed: 1-case was matched with 3-controls based on SOT type, transplant center, and time post-SOT...
April 18, 2018: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/29668049/surgical-management-of-spontaneous-cerebrospinal-fistulas-and-encephaloceles-of-the-temporal-bone
#5
Joe Walter Kutz, Andrew K Johnson, Cameron C Wick
OBJECTIVES/HYPOTHESIS: To describe the presentation, surgical findings, and outcomes in patients with spontaneous temporal bone cerebrospinal fluid (CSF) fistulas and encephaloceles. STUDY DESIGN: Retrospective chart review. METHODS: A retrospective chart review of patients treated for a spontaneous temporal bone CSF fistula and/or encephalocele over a 10-year period was performed. Data recorded included demographic information, presenting signs and symptoms, radiographic and laboratory studies, surgical approach, materials used for repair, surgical complications, and successful closure of the CSF fistula...
April 18, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29668040/graft-loss-attributed-to-possible-transfusion-transmitted-ehrlichiosis-following-cord-blood-stem-cell-transplant
#6
A Mah, G M Viola, E Ariza Heredia, K Rezvani, P Kebriaei, M M Bhatti, X Han, E J Shpall, V Mulanovich
We present a case of possible transfusion-transmitted Ehrlichia chaffeensis infection in a heavily transfused cord blood transplant recipient, resulting in severe infection and graft loss. Transfusion-transmitted, vector-borne infections in immunocompromised individuals can have severe consequences, and should be considered in hospitalized patients receiving blood products with unexplained fever or sepsis. This article is protected by copyright. All rights reserved.
April 18, 2018: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/29668016/genetic-and-ecological-niche-modeling-of-calydorea-crocoides-iridaceae-an-endemic-species-of-subtropical-highland-grasslands
#7
Juliana Lustosa Matos de Alencar, Eliane Kaltchuk-Santos, Juliana Fachinetto, Luana Olinda Tacuatiá, Eliana Regina Forni-Martins, Eudes Maria Stiehl-Alves, Tatiana Teixeira de Souza-Chies
Evolutionary analyses have been widely used for evaluation of genetic diversity of natural populations and correlate these data to the fitness of the species, especially in the case of threatened species. Calydorea crocoides occurs in a restricted area at altitudes from 800 to 1500 m in southern Brazil and is considered endangered. A study assessing genetic diversity, cytogenetic features and ecological niche was performed aiming to characterize C. crocoides by multidisciplinary approaches. Molecular data highlighted that most of the total variation (76%; p < 0...
2018: Genetics and Molecular Biology
https://www.readbyqxmd.com/read/29667938/suggested-design-of-gold-nanoobjects-based-terahertz-radiation-source-for-biomedical-research
#8
Andrei Postnikov, Kamil Moldosanov
Gold nanoparticles (GNPs) may serve as "devices" to emit electromagnetic radiation in the terahertz (THz) range, whereby the energy is delivered by radio frequency or microwave photons which won't by themselves induce transitions between sparse confinement-shaped electron levels of a GNP, but may borrow the energy from longitudinal acoustic phonons to overcome the confinement gap. Upon excitation, the Fermi electron cannot relax otherwise than via emitting a THz photon, the other relaxation channels being blocked by force of shape and size considerations...
April 18, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29667860/educational-needs-in-the-diagnosis-and-management-of-pediatric-functional-constipation-a-us-survey-of-specialist-and-primary-care-clinicians
#9
Justin Barnes, Brandon Coleman, Sharon Hwang, Aleksandra Stolic, Athos Bousvaros, Samuel Nurko, Gregory D Salinas
OBJECTIVES: The goal of this study was to identify opportunities among gastroenterologists and gastroenterology nurse practitioners (NPs)/physician assistants (PAs) for continuing medical education (CME) related to functional constipation. METHODS: An online, case-vignette survey was designed to identify and quantify practice patterns of pediatric gastroenterology clinicians. Case vignettes are a validated method for assessing clinician practice patterns. The survey consisted of three patient cases: a 3-year-old female with a 6-month history of constipation; a 6-year-old male with a 1-year history of constipation refractory to treatment and a sacral dimple with nearby tuft of hair; and a 16-year-old male with a 10-year history of constipation, and a sullen, depressed mood...
April 18, 2018: Postgraduate Medicine
https://www.readbyqxmd.com/read/29667738/visual-outcome-in-cats-with-hypertensive-chorioretinopathy
#10
Whitney M Young, Chaowen Zheng, Michael G Davidson, Hans D Westermeyer
PURPOSE: To investigate factors associated with long-term visual outcome in cats with hypertensive chorioretinopathy. ANIMALS STUDIED: Eighty-eight client-owned cats diagnosed with hypertensive chorioretinopathy. PROCEDURE: Medical records from cats with systemic hypertension and associated retinal lesions were reviewed. RESULTS: Most cats (61%) were blind in both eyes at presentation. Presence of menace response at last follow-up evaluation was positively correlated with presence of menace response at presentation (P = ...
April 18, 2018: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/29667709/the-outlet-patch-gastric-heterotopia-of-the-colo-rectum-and-anus
#11
Abul Ala Syed Rifat Mannan, Michael Vieth, Armen Khararjian, Binny Khandakar, Dora Lam-Himlin, David Heydt, Feriyl Bhaijee, Henry J Venbrux, Kathleen Byrnes, Lysandra Voltaggio, Norman Barker, Songyang Yuan, Elizabeth Montgomery
AIMS: Gastric heterotopia (GH) has been described throughout the gastrointestinal tract. However, the colorectal region is an extremely rare location for it. We describe the clinicopathologic features of GH of the colon, rectum, and anus. METHODS AND RESULTS: We identified 33 cases in 20 males and 13 females (median age 54 years; range, 4 months to 73 years). Sites included the rectum (N=26), anus (N=4), ileocecal junction (N=1), ascending colon (N=1) and descending colon (N=1)...
April 18, 2018: Histopathology
https://www.readbyqxmd.com/read/29667679/vibrational-spectroscopy-of-hydrogens-in-diamond-a-quantum-mechanical-treatment
#12
Francesco Silvio Gentile, Simone Salustro, Jacques Kontak Desmarais, Anna Maria Ferrari, Philippe D'Arco, Roberto Dovesi
The electronic and vibrational features of the VHn (n = 1 to 4) family of defects in diamond (hydrogen atoms saturating the dangling bonds of the atoms surrounding a vacancy) are investigated at the quantum mechanical level by using the periodic supercell approach, an all electron Gaussian type basis set, hybrid functionals, and the Crystal code. Most of the results have been collected for supercells containing 64 atoms; however, in order to explore the effect of the defect concentration on both the IR and Raman spectra, supercells containing 216, 512 and 1000 atoms have also been considered in the VH4 case...
April 18, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29667639/-a-change-in-the-direction-of-the-wound-channel-in-the-case-of-the-combined-injury-inflicted-by-a-shot-from-the-9-0-mm-makarov-pistol
#13
A A Gusarov, I Yu Makarov, V A Fetisov
The authors present an example from the expert practice demonstrating the influence of such factors as the properties of the ammunition fired from a weapon (including its weight, size, shape, and speed) as well as the anatomical features of the body tissues being affected on the mechanism of formation of a gunshot wound in the human body. The investigation of the suicide of subject P. has demonstrated the penetrating bullet wound of the neck and the head. The entrance wound was located at the anterior neck surface and the exit one in the left half of the occipital region...
2018: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/29667638/-the-forensic-medical-aspects-of-the-inappropriate-medical-care-in-the-modern-day-ukraine
#14
V V Franchuk
Despite the fact that the ever growing relevance of the problem of the inappropriate medical care was long ago brought to the worldwide attention, it has not been practically addressed in the Ukraine since the country gained independence in 1991. The objective of the present study was to consider the specific features of expert examination of the cases of inappropriate medical care as exemplified by the materials of the legal actions and lawsuits instituted against healthcare specialists violating their occupational duties...
2018: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/29667637/-the-expert-characteristic-of-the-forensic-medical-documentation-for-the-purpose-of-investigations-of-the-injuries-to-the-maxillofacial-region
#15
V L Popov, M O Yagmurov, E L Troshin
The injuries to the maxillofacial region (MFR) are among the most frequently occurring problems encountered if the forensic medical practice. The objective of the present study was the analysis of the quality of the medical record documentation of the victims of the injuries to the maxillofacial region for obtaining the information necessary for forensic medical experts to make the well-founded conclusions. We undertook the in-depth analysis of random samples from the materials stored in the archive of living subjects at the Saint-Petersburg Bureau of forensic medical expertise for the period from 2010 to 2014...
2018: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/29667630/-the-principal-and-auxiliary-immunohistochemical-markers-of-intravital-mechanical-strangulation-asphyxia
#16
D V Bogomolov, V A Fetisov, O P Denisova, Yu V Zbrueva, G G Semenov
The objective of the present study was the evaluation of the auxiliary methods for the diagnostics of the intravital formation of the constriction marks; the secondary objective was to determine the pace at which the death and asphyxia occur. MATERIAL AND METHODS: The materials on which the study was based included 17 cases of mechanical strangulation asphyxia involving 13 men and 4 women at the age from 8 to 28 years. All cases of hanging were associated with different blood alcohol levels...
2018: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/29667607/blunt-abdominal-trauma-following-gunshot-wound-case-report-and-literature-review
#17
Myftar Torba, Arben Gjata, Francesco Rulli, Ilir Kajo, Sotir Ceka, Afron Mici
Blunt abdominal trauma following gunshot wound. Case report and literature review Introduction: Similarly to blast weapons, every firearm produces explosion at the moment of shooting, which can cause injuries in every region of the body. The aim of this paper is to present the mechanism of blunt abdominal injury following gunshot wounds, bringing this uncommon disease to the clinicians' attention and to review the literature available. CASE REPORT: A patient developed a delayed bowel perforation following a gunshot injury of the abdomen without breaking of the peritoneum...
April 20, 2018: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/29667600/is-eye-lens-dosimetry-needed-in-nuclear-medicine
#18
Malgorzata Wrzesien, Leszek Krolicki, Lukasz Albiniak, Jerzy Olszewski
INTRODUCTION: The specificity of personnel exposure, which distinguishes nuclear medicine, is associated with the form of the radiation source used, and this often requires performing manual procedures while using radioactive isotopes. The variety of radionuclides and medical procedures, and the yearly increase in the number of patients, as well as the change of the individual dose limit for the lens of the eye from a value of 150 mSv per year to a level of 20 mSv, means that issues of eye lens routine dosimetry become interesting from the radiation protection point of view...
April 18, 2018: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/29667576/case-of-seasonal-reassortant-a-h1n2-influenza-virus-infection-the-netherlands-march-2018
#19
Adam Meijer, Corien M Swaan, Martin Voerknecht, Edin Jusic, Sharon van den Brink, Lisa A Wijsman, Bettie Cg Voordouw, Gé A Donker, Jacqueline Sleven, Wendelien W Dorigo-Zetsma, Sanela Svraka, Michiel van Boven, Manon R Haverkate, Aura Timen, Jaap T van Dissel, Marion Pg Koopmans, Theo M Bestebroer, Ron Am Fouchier
A seasonal reassortant A(H1N2) influenza virus harbouring genome segments from seasonal influenza viruses A(H1N1)pdm09 (HA and NS) and A(H3N2) (PB2, PB1, PA, NP, NA and M) was identified in March 2018 in a 19-months-old patient with influenza-like illness (ILI) who presented to a general practitioner participating in the routine sentinel surveillance of ILI in the Netherlands. The patient recovered fully. Further epidemiological and virological investigation did not reveal additional cases.
April 2018: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/29667525/the-association-between-bronchial-asthma-and-periodontitis-a-case-control-study-in-jordan
#20
Basheer Khassawneha, Rola Alhabashnehb, Fadi Ibrahimc
OBJECTIVE: Our aim is to study the association between bronchial asthma (BA) and periodontitis in northern Jordan. METHODS: A case-control study of 260 subjects; 130 with BA and 130 without BA (controls) were recruited from pulmonary clinics at a university hospital in northern Jordan. BA was physician diagnosed and on anti-asthma medications for ≥12 months. Periodontitis was defined as the presence of ≥ 4 teeth with ≥ 1 site with probing pocket depth (PPD) ≥ 4 mm and clinical attachment level (CAL) ≥ 3 mm...
April 18, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
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