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Akylosing spondylitis

Liudan Tu, Jayanti Chamling Rai, Shuangyan Cao, Zhiming Lin, Zaiying Hu, Jieruo Gu
OBJECTIVES: To access the annual direct, indirect costs and work limitation of AS patients in Chinese population and explore the determinants of cost. METHODS: A retrospective, cross-sectional study was performed in 257 patients with AS in China. The participants completed questionnaires about disease characteristics, quality of life and direct and indirect costs. Only the patients with paid-work completed the Work Limitation Questionnaire (WLQ), a 25-item questionnaire that accesses the impact of chronic health conditions on job performance and productivity...
September 2014: Clinical and Experimental Rheumatology
R W Karr, Y Hahn, B D Schwartz
Although the association between human histocompatibility leukocyte antigen (HLA) B27 and ankylosing spondylitis is the prototype of HLA-disease association, the mechanism underlying these associations has not been determined. We have investigated the possibility that the B27 molecules from patients with ankylosing spondylitis are different from those of normals, and only the "different" molecules predispose the individual to disease. Biosynthetically radiolabeled HLA-B27 molecules from patients with ankylosing spondylitis and normal individuals were compared by two-dimensional gel electrophoresis and tryptic peptide mapping with high pressure liquid chromatography...
February 1982: Journal of Clinical Investigation
M J McMaster, M B Coventry
No abstract text is available yet for this article.
July 1973: Mayo Clinic Proceedings
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