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Aquatic therapy

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https://www.readbyqxmd.com/read/29468553/crispr-cas9-mediated-knockout-of-rb1-in-xenopus-tropicalis
#1
Thomas Naert, Kris Vleminckx
At this time, no molecular targeted therapies exist for treatment of retinoblastoma. This can be, in part, attributed to the lack of animal models that allow for both rapid identification of novel therapeutic targets and hypothesis driven drug testing. Within this scope, we have recently reported the first genuine genetic nonmammalian retinoblastoma cancer model within the aquatic model organism Xenopus tropicalis (Naert et al., Sci Rep 6: 35263, 2016). Here we describe the methods to generate rb1 mosaic mutant Xenopus tropicalis by employing the CRISPR/Cas9 technology...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29458923/a-bicentric-controlled-study-on-the-effects-of-aquatic-ai-chi-in-parkinson-disease
#2
Sagrario Pérez-de la Cruz
OBJECTIVES: Various exercise strategies have been suggested to address movement deficits in order to improve motor function and quality of life for individuals in the early or moderate stages of Parkinson disease. The purpose is to evaluate the effects of an aquatic Ai Chi intervention on balance, gait speed and quality of life of patients. DESIGN AND INTERVENTION: Twenty-nine people with Parkinson disease participated in this pilot study. People were randomized into (1) aquatic Ai Chi program (experimental group) and (2) a dry land conventional Western physical therapy intervention (control group)...
February 2018: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/29407696/trace-analysis-of-61-natural-and-synthetic-progestins-in-river-water-and-sewage-effluents-by-ultra-high-performance-liquid-chromatography-tandem-mass-spectrometry
#3
Xiaoyan Shen, Hong Chang, Dezhi Sun, Linxia Wang, Fengchang Wu
A broad number of natural and synthetic progestins are widely used in human and veterinary therapies. Although progestins exhibit adverse effects in aquatic organisms, information about environmental occurrence and fate have been limited to several compounds, hampering the accuracy of risk assessments of the compounds. In this study, a selective and sensitive analytical method was established to simultaneously determine 19 natural and 42 synthetic progestins in environmental waters, and the synthetic progestins included 19-nortestosterone, 17α-hydroxyprogesterone and progesterone derivatives...
February 1, 2018: Water Research
https://www.readbyqxmd.com/read/29394027/coordination-complexes-of-titanium-iv-for-anticancer-therapy
#4
Edit Y Tshuva, Maya Miller
Titanium(IV) coordination complexes represent attractive alternatives to platinumbased anticancer drugs. The advantage of the titanium metal lies in its low toxicity, and the hydrolysis of titanium(IV) coordination complexes in biological water-based environment to the safe and inert titanium dioxide is an enormous benefit. On the other hand, the rapid hydrolysis of titanium(IV) complexes in biological environment and their rich aquatic chemistry hampered the exploration and the development of effective compounds...
February 5, 2018: Metal Ions in Life Sciences
https://www.readbyqxmd.com/read/29322273/the-emerging-influenza-virus-threat-status-and-new-prospects-for-its-therapy-and-control
#5
REVIEW
Binod Kumar, Kumari Asha, Madhu Khanna, Larance Ronsard, Clement Adebajo Meseko, Melvin Sanicas
Influenza A viruses (IAVs) are zoonotic pathogens that cause yearly outbreaks with high rates of morbidity and fatality. The virus continuously acquires point mutations while circulating in several hosts, ranging from aquatic birds to mammals, including humans. The wide range of hosts provides influenza A viruses greater chances of genetic re-assortment, leading to the emergence of zoonotic strains and occasional pandemics that have a severe impact on human life. Four major influenza pandemics have been reported to date, and health authorities worldwide have shown tremendous progress in efforts to control epidemics and pandemics...
January 10, 2018: Archives of Virology
https://www.readbyqxmd.com/read/29313176/effectiveness-of-a-multisystem-aquatic-therapy-for-children-with-autism-spectrum-disorders
#6
Giovanni Caputo, Giovanni Ippolito, Marina Mazzotta, Luigi Sentenza, Mara Rosaria Muzio, Sara Salzano, Massimiliano Conson
Aquatic therapy improves motor skills of persons with Autism Spectrum Disorders (ASD), but its usefulness for treating functional difficulties needs to be verified yet. We tested effectiveness of a multisystem aquatic therapy on behavioural, emotional, social and swimming skills of children with ASD. Multisystem aquatic therapy was divided in three phases (emotional adaptation, swimming adaptation and social integration) implemented in a 10-months-programme. At post-treatment, the aquatic therapy group showed significant improvements relative to controls on functional adaptation (Vineland Adaptive Behavior Scales), emotional response, adaptation to change and on activity level (Childhood Autism Rating Scale)...
January 8, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29283402/real-time-monitoring-and-analysis-of-zebrafish-electrocardiogram-with-anomaly-detection
#7
Michael Lenning, Joseph Fortunato, Tai Le, Isaac Clark, Ang Sherpa, Soyeon Yi, Peter Hofsteen, Geethapriya Thamilarasu, Jingchun Yang, Xiaolei Xu, Huy-Dung Han, Tzung K Hsiai, Hung Cao
Heart disease is the leading cause of mortality in the U.S. with approximately 610,000 people dying every year. Effective therapies for many cardiac diseases are lacking, largely due to an incomplete understanding of their genetic basis and underlying molecular mechanisms. Zebrafish (Danio rerio) are an excellent model system for studying heart disease as they enable a forward genetic approach to tackle this unmet medical need. In recent years, our team has been employing electrocardiogram (ECG) as an efficient tool to study the zebrafish heart along with conventional approaches, such as immunohistochemistry, DNA and protein analyses...
December 28, 2017: Sensors
https://www.readbyqxmd.com/read/29172739/effect-of-aquatic-exercise-on-mental-health-functional-autonomy-and-oxidative-dysfunction-in-hypertensive-adults
#8
Luciano Acordi Da Silva, Lorhan Menguer, Janaina Motta, Beatriz Dieke, Sindianra Mariano, Gladson Tasca, Rubya Pereira Zacaron, Paulo Cesar Lock Silveira, Pinho Ricardo Aurino
The aquatic exercise is an effective non-pharmacological therapy for prevention and control of hypertension. The objective of the present study was to investigate the effect of aquatic exercise on mental health, functional autonomy, and oxidative dysfunction in hypertensive adults. Methodologically 29 adults (mean age 53 ± 7.5 years) were included in the study, and were randomly grouped as hypertensive (n = 16) and non-hypertensive (n = 13). Both groups underwent low-intensity aquatic exercise program for 12 weeks...
November 27, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/29132820/optimization-and-application-of-fabric-phase-sorptive-extraction-coupled-to-ultra-high-performance-liquid-chromatography-tandem-mass-spectrometry-for-the-determination-of-cytostatic-drug-residues-in-environmental-waters
#9
Sergio Santana-Viera, Rayco Guedes-Alonso, Zoraida Sosa-Ferrera, José Juan Santana-Rodríguez, Abuzar Kabir, Kenneth G Furton
Every year, hundreds of tons of organic pollutants reach the environment through effluents released from wastewater treatment plants worldwide, and many of these compounds have harmful effects on the aquatic ecosystem. A new class of emerging pollutants of high concern is cytostatic drugs, which are designed to treat different types of cancers by attacking cells. Environmental concentrations of cytostatic drugs are known to be in the range of ngL(-1), and for this reason, it is imperative to develop analytical methods of extraction and preconcentration to allow for subsequent instrumental analysis of these drugs...
November 4, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29109372/marine-algae-as-source-of-novel-antileishmanial-drugs-a-review
#10
REVIEW
Lauve Rachel Tchokouaha Yamthe, Regina Appiah-Opong, Patrick Valere Tsouh Fokou, Nole Tsabang, Fabrice Fekam Boyom, Alexander Kwadwo Nyarko, Michael David Wilson
Leishmaniasis is a vector-borne neglected tropical disease caused by protozoan parasites of the Leishmania genus and transmitted by the female Phlebotomus and Lutzomyia sand flies. The currently prescribed therapies still rely on pentavalent antimonials, pentamidine, paromomycin, liposomal amphotericin B, and miltefosine. However, their low efficacy, long-course treatment regimen, high toxicity, adverse side effects, induction of parasite resistance and high cost require the need for better drugs given that antileishmanial vaccines may not be available in the near future...
October 29, 2017: Marine Drugs
https://www.readbyqxmd.com/read/29096309/evaluation-of-acute-and-chronic-ecotoxicity-of-cyclophosphamide-ifosfamide-their-metabolites-transformation-products-and-uv-treated-samples
#11
Chiara Russo, Margherita Lavorgna, Marjeta Česen, Tina Kosjek, Ester Heath, Marina Isidori
Cyclophosphamide (CP) and Ifosfamide (IF) are two nitrogen mustard drugs widely prescribed in cancer therapy. They are continuously released via excreta into hospital and urban wastewaters reaching wastewater treatment plants. Although CP and IF, their metabolites and transformation products (TPs) residues have been found in the aquatic environment from few ng L(-1) to tens of μg L(-1), their environmental toxic effects are still not well known. The present study aimed to investigate the acute and chronic ecotoxicity of CP and IF and their commercially available human metabolites/TPs, i...
October 27, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29068939/watch-out-for-wild-animals-a-systematic-review-of-upper-extremity-injuries-caused-by-uncommon-species
#12
REVIEW
Jacqueline S Israel, James E McCarthy, Katherine R Rose, Venkat K Rao
BACKGROUND: Across the world, many species of nondomesticated animals dwell among humans in metropolitan areas. Rare animal bites pose a dilemma for hand surgeons, as they often result in operative injuries and recalcitrant infections. The authors treated an 85-year-old man who experienced severe cellulitis of the index finger following an opossum bite. This case prompted a systematic review of upper extremity injuries caused by species other than dogs, cats, snakes, and insects. METHODS: The authors conducted a systematic review of PubMed and Scopus databases to identify relevant articles published between 1980 and 2016...
November 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29022660/-food-borne-trematodiases
#13
Remco Kruithof, Véronique Erard
Food-borne trematodiases (flukes) are transmitted through the consumption of contaminated undercooked aquatic food. Infections are most prevalent in Southeast Asia and Latin America, but might occur anywhere due to food trade, international travel, human migration. Clinical manifestations are hepatobiliary, intestinal, and pleuropulmonary. The worse complication is development of cholangiocarcinoma. Efficacious drug therapy are available, however prevention control measures are essential to avoid transmission...
October 11, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28983663/the-role-of-land-and-aquatic-exercise-in-ankylosing-spondylitis-a-systematic-review
#14
REVIEW
Ana Zão, Pedro Cantista
Ankylosing spondylitis (AS) is a chronic and inflammatory rheumatic disease, characterized by pain and structural and functional impairments, such as reduced mobility and axial deformity, which lead to diminished quality of life. Its treatment includes not only drugs, but also nonpharmacological therapy. Exercise appears to be a promising modality. The aim of this study is to review the current evidence and evaluate the role of exercise either on land or in water for the management of patients with AS in the biological era...
December 2017: Rheumatology International
https://www.readbyqxmd.com/read/28933572/what-areas-of-functioning-are-influenced-by-aquatic-physiotherapy-experiences-of-parents-of-children-with-cerebral-palsy
#15
Javier Güeita-Rodríguez, Francisco García-Muro, Ángel L Rodríguez-Fernández, Johan Lambeck, Cesar Fernández-de-Las-Peñas, Domingo Palacios-Ceña
OBJECTIVES: To explore the experiences regarding aquatic physiotherapy among parents of children with cerebral palsy and to identify a list of relevant intervention categories for aquatic physiotherapy treatments. METHODS: We conducted semi-structured interviews and focus groups using the components of the International Classification of Functioning, Disability and Health (ICF) as a frame of reference to explore and code experiences regarding aquatic physiotherapy...
September 21, 2017: Developmental Neurorehabilitation
https://www.readbyqxmd.com/read/28929212/an-insight-into-phage-diversity-at-environmental-habitats-using-comparative-metagenomics-approach
#16
Krupa Parmar, Nishant Dafale, Rajesh Pal, Hitesh Tikariha, Hemant Purohit
Bacteriophages play significant role in driving microbial diversity; however, little is known about the diversity of phages in different ecosystems. A dynamic predator-prey mechanism called "kill the winner" suggests the elimination of most active bacterial populations through phages. Thus, interaction between phage and host has an effect on the composition of microbial communities in ecosystems. In this study, secondary phage metagenome data from aquatic habitats: wastewater treatment plant (WWTP), fresh, marine, and hot water spring habitat were analyzed using MG-RAST and STAMP tools to explore the diversity of the viruses...
September 19, 2017: Current Microbiology
https://www.readbyqxmd.com/read/28923661/the-influence-of-the-aquatic-environment-on-the-center-of-pressure-impulses-and-upper-and-lower-trunk-accelerations-during-gait-initiation
#17
Andresa R Marinho-Buzelli, Kei Masani, Hossein Rouhani, Ana M Barela, Gustavo T B Fernandes, Mary C Verrier, Milos R Popovic
Gait initiation is defined as the transition from stationary standing to steady-state walking. Despite the frequent use of therapy pools for training walking in early stages of rehabilitation, none have been reported on the effects of immersion on gait initiation. We aimed to analyze the center of pressure (COP) trajectories, the vertical and anteroposterior impulses and upper and lower trunk accelerations during anticipatory (APA) and execution phases of gait initiation. In the COP trajectory, the execution (EXE) phase was further subdivided in two phases: predominantly mediolateral (EXE1), and predominantly anteroposterior (EXE2)...
October 2017: Gait & Posture
https://www.readbyqxmd.com/read/28918118/case-report-aquatic-therapy-and-end-stage-dementia
#18
Bruce E Becker, Stacy Lynch
A 54-year-old woman, retired due to progressive cognitive decline, was diagnosed with early-onset Alzheimer dementia. Conventional medication therapy for dementia had proven futile. Initial evaluation revealed a nonverbal female seated in a wheelchair, dependent on 2-person assist for all transfers and activities of daily living. She had been either nonresponsive or actively resistive for both activities of daily living and transfers in the 6 months before assessment. After a total of 17 1-hour therapy sessions over 19 weeks in a warm water therapy pool, she achieved the ability to tread water for 15 minutes, transfers improved to moderate-to-maximum assist from seated, and ambulation improved to 1000 feet with minimum-to-moderate assist of 2 persons...
September 14, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28895998/-effects-of-an-intensive-thalassotherapy-and-aquatic-therapy-program-in-stroke-patients-a-pilot-study
#19
C Morer, C Boestad, P Zuluaga, A Alvarez-Badillo, F Maraver
INTRODUCTION: Stroke remains the leading cause of acquired disability. Health and social planning and management may vary and although prevention is crucial, having better treatments and strategies to reduce disability is needed. AIM: To determine the effect of an intensive program of thalassotherapy and aquatic therapy in stroke patients, valuing clinical parameters and functional validated scales. PATIENTS AND METHODS: A quasi-experimental prospective study consisting of a specific program assessed pre- and post- 3 weeks treatment to 26 stroke patients with a mild-moderate disability...
September 16, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28864911/the-effectiveness-of-aquatic-group-therapy-for-improving-water-safety-and-social-interactions-in-children-with-autism-spectrum-disorder-a-pilot-program
#20
Michele L Alaniz, Sheila S Rosenberg, Nicole R Beard, Emily R Rosario
Drowning is the number one cause of accidental death in children with Autism Spectrum Disorder (ASD). Few studies have examined the effectiveness of swim instruction for improving water safety skills in children with moderate to severe ASD. This study examines the feasibility and effectiveness of an aquatic therapy program on water safety and social skills in children with mild to severe ASD (n = 7). Water safety skills were evaluated using the Aquatics Skills Checklist and social skills were measured using the Social Skills Improvement Scale...
December 2017: Journal of Autism and Developmental Disorders
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