keyword
https://read.qxmd.com/read/38206626/mediating-factors-in-the-association-of-maternal-educational-level-with-pregnancy-outcomes-a-mendelian-randomization-study
#21
JOURNAL ARTICLE
Tormod Rogne, Dipender Gill, Zeyan Liew, Xiaoting Shi, Vilde Hatlevoll Stensrud, Tom Ivar Lund Nilsen, Stephen Burgess
IMPORTANCE: Lower educational attainment is associated with increased risk of adverse pregnancy outcomes, but it is unclear which pathways mediate this association. OBJECTIVE: To investigate the association between educational attainment and pregnancy outcomes and the proportion of this association that is mediated through modifiable cardiometabolic risk factors. DESIGN, SETTING, AND PARTICIPANTS: In this 2-sample mendelian randomization (MR) cohort study, uncorrelated (R2 < 0...
January 2, 2024: JAMA Network Open
https://read.qxmd.com/read/38196047/full-trisomy-14-in-one-of-bichorionic-biamniotic-twins
#22
JOURNAL ARTICLE
Dubravko Habek, Anis Cerovac
We describe the case of the lethal full trisomy (T) 14 in a fetus from bichorionic biamniotic (BCBA) twin pregnancy. This is a case of a 28-year-old primigravida, with an unremarkable personal and family history, who just like her 30-year-old husband, was without consanguinity between spouses. She conceived spontaneously, without a burdened gynecological-obstetric history. By the 12th week of pregnancy, she had hyperemesis gravidarum and one episode of bleeding due to which progesterone supplementation was prescribed...
January 9, 2024: Zeitschrift Für Geburtshilfe und Neonatologie
https://read.qxmd.com/read/38131521/the-impact-of-maternal-hyperemesis-gravidarum-on-early-childhood-respiratory-morbidity
#23
JOURNAL ARTICLE
Guy Hazan, Eyal Sheiner, Inbal Golan-Tripto, Aviv Goldbart, Ruslan Sergienko, Tamar Wainstock
BACKGROUND: Lung maldevelopment due to in-utero events may potentially cause respiratory morbidity during childhood. Maternal nutritional status during pregnancy is critical for lung development. This study is contributing to the understanding of the interplay between maternal nutrition status during pregnancy, fetal lung development and the risk for respiratory diseases in early life. RESEARCH QUESTION: To investigate the association between maternal hyperemesis gravidarum (HG) during pregnancy and respiratory morbidity in the offspring's early childhood...
December 22, 2023: Pediatric Pulmonology
https://read.qxmd.com/read/38099324/effects-of-foot-massage-in-pregnant-women-with-hyperemesis-gravidarum-on-severity-of-nausea-vomiting-and-anxiety
#24
JOURNAL ARTICLE
Nilay Gökbulut, Yeşim Aksoy Derya
OBJECTIVE: This study was conducted to determine the effects of foot massage performed on pregnant women with hyperemesis gravidarum on the severity of nausea and vomiting and pregnancy-related anxiety. MATERIAL AND METHOD: This randomised controlled study was conducted between February and November 2020 with 104 pregnant women hospitalised in the pregnant women follow-up service ward of a public hospital in eastern Turkey with the diagnosis of hyperemesis gravidarum...
December 15, 2023: Journal of Reproductive and Infant Psychology
https://read.qxmd.com/read/38094894/breastfeeding-women-in-need-of-information-about-antiemetics-for-nausea-and-vomiting-during-pregnancy-a-review-of-inquiries-to-a-medicines-information-service
#25
JOURNAL ARTICLE
Kristine Heitmann, Tina Bakkebø, Gro C Havnen, Jan Schjøtt
Introduction: The medicines information service, SafeMotherMedicine, regularly receives inquiries from breastfeeding women asking about antiemetics for nausea and vomiting during pregnancy (NVP) or hyperemesis gravidarum (HG). However, treatment guidelines for NVP or HG do not address the use of antiemetics in women who are breastfeeding while becoming pregnant again. Our objective was to characterize inquiries to describe the need for lactation risk information among women with NVP or HG and also to raise awareness of this topic...
2023: Frontiers in Pharmacology
https://read.qxmd.com/read/38092039/gdf15-linked-to-maternal-risk-of-nausea-and-vomiting-during-pregnancy
#26
JOURNAL ARTICLE
M Fejzo, N Rocha, I Cimino, S M Lockhart, C J Petry, R G Kay, K Burling, P Barker, A L George, N Yasara, A Premawardhena, S Gong, E Cook, D Rimmington, K Rainbow, D J Withers, V Cortessis, P M Mullin, K W MacGibbon, E Jin, A Kam, A Campbell, O Polasek, G Tzoneva, F M Gribble, G S H Yeo, B Y H Lam, V Saudek, I A Hughes, K K Ong, J R B Perry, A Sutton Cole, M Baumgarten, P Welsh, N Sattar, G C S Smith, D S Charnock-Jones, A P Coll, C L Meek, S Mettananda, C Hayward, N Mancuso, S O'Rahilly
GDF15, a hormone acting on the brainstem, has been implicated in the nausea and vomiting of pregnancy, including its most severe form, hyperemesis gravidarum (HG), but a full mechanistic understanding is lacking1-4 . Here we report that fetal production of GDF15 and maternal sensitivity to it both contribute substantially to the risk of HG. We confirmed that higher GDF15 levels in maternal blood are associated with vomiting in pregnancy and HG. Using mass spectrometry to detect a naturally labelled GDF15 variant, we demonstrate that the vast majority of GDF15 in the maternal plasma is derived from the feto-placental unit...
December 13, 2023: Nature
https://read.qxmd.com/read/38074267/anemia-burden-in-pregnancy-and-birth-outcomes-among-women-receiving-antenatal-care-services-from-a-secondary-level-hospital-in-south-india-a-record-review
#27
JOURNAL ARTICLE
Bhoomika Biradar, Sakthi Arasu, Naveen Ramesh
INTRODUCTION: Anaemia in pregnant women is a major public health problem and is associated with adverse outcomes both in pregnant mothers and new-borns. According to NFHS-5, 45.7% of women in urban India were affected by anaemia during their pregnancy. The objectives of this study were to estimate the proportion of pregnant women who were anaemic and its effect on maternal and birth outcomes, and additionally, to assess the various socio-economic factors contributing to anaemia during pregnancy...
October 2023: Journal of Family Medicine and Primary Care
https://read.qxmd.com/read/38074045/an-interesting-presentation-of-pneumomediastinum-secondary-to-hyperemesis-gravidarum-in-the-second-trimester
#28
Nida Ansari, Sacide S Ozgur, Robert Giannetti, Faith Powell, Patrick Michael
We present a rare case of pneumomediastinum in the setting of hyperemesis gravidarum. Pneumomediastinum is a condition characterized by the presence of air leaking into the mediastinum. Often secondary to trauma, there remains the potential for it to develop spontaneously. This is a time-sensitive diagnosis that requires vigilance for effective treatment. A 21-year-old gravida 1 para 0 female at 15 weeks of gestation with no significant past medical history presented to the emergency department complaining of four weeks of daily nausea and vomiting and two weeks of chest pain, cough, and difficulty breathing...
November 2023: Curēus
https://read.qxmd.com/read/38073670/intrauterine-fetal-death-due-to-fetal-intracranial-hemorrhage-associated-with-maternal-vitamin-k-deficiency-a-case-report
#29
Koya Yasuda, Soichiro Obata, Eita Kumagai, Takayoshi Iijima, Masafumi Yamamoto, Etsuko Miyagi, Shigeru Aoki
Vitamin K deficiency can cause coagulopathy; therefore, supplementation is recommended to prevent intracranial hemorrhage in newborns. Some reports have shown that maternal vitamin K deficiency is associated with intracranial hemorrhage in the fetus. However, no clear guidelines exist for the diagnosis and treatment of maternal vitamin K deficiency to prevent fetal intracranial hemorrhage. We report a case of intrauterine fetal death due to intracranial hemorrhage associated with maternal vitamin K deficiency resulting from hyperemesis gravidarum...
December 2023: Case Reports in Women's Health
https://read.qxmd.com/read/38039028/effect-of-grand-multiparity-on-maternal-obstetric-fetal-and-neonatal-results
#30
JOURNAL ARTICLE
Y Başkiran, K Uçkan, I Çeleğen
OBJECTIVE: The aim of the study was to compare the incidence of antenatal and intrapartum complications and perinatal outcomes between grand multiparous women of the same age and socioeconomic status and nulliparous and multiparous women. PATIENTS AND METHODS: A prospective case-control study was conducted at the Tertiary Center Gynecology and Obstetrics Clinic of the Eastern Anatolia Region between January 1, 2021, and January 1, 2023. It was compared with 149 grand multiparous, 724 multipara, and 258 nulliparous singleton pregnancies...
November 2023: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/38021939/intrauterine-fetal-demise-a-rare-complication-of-wernicke-s-encephalopathy-secondary-to-hyperemesis-gravidarum
#31
Anthony Pham, Robin Okpara, Nancy Rollins, Roy Jacob
Wernicke's encephalopathy (WE) is an acute neurological disorder caused by severe thiamine deficiency that manifests with a common range of clinical features including a triad of global confusion state, ophthalmoplegia, and ataxia. Though frequently associated with the alcohol-dependent population, WE has been seen in other patients where it often goes undiagnosed presumably due to rarity and variable clinical indications. In this case report, we highlight the importance of WE being considered as a differential diagnosis of acute encephalopathy particularly in women who have experienced fetal demise in conjunction with signs of malnourishment from hyperemesis gravidarum...
October 2023: Curēus
https://read.qxmd.com/read/38009269/the-association-between-helicobacter-pylori-and-gastrointestinal-disorders-during-pregnancy-a-multicenter-retrospective-study
#32
JOURNAL ARTICLE
Yun Feng, Qing Huang, Miaosha Luo, Jia Wei, Tiantian Gao, Dake Chu, Ai Jia, Yingchao Li, Shuixiang He, Tianjiao Duan
BACKGROUND: Some gastrointestinal disorders may be associated with Helicobacter pylori infection, which not only affect maternal health, but may also lead to adverse pregnancy outcomes. We aim to explore the association between H. pylori and gastrointestinal disorders in pregnant women. MATERIALS AND METHODS: In total, 503 patients were retrospectively analyzed and divided into the H. pylori-uninfected group, the H. pylori-infected group, or the H...
November 27, 2023: Helicobacter
https://read.qxmd.com/read/37929347/correlation-between-serum-beta-human-chorionic-gonadotropin-levels-and-thyroid-metabolic-function-in-pregnant-women-with-hyperemesis-gravidarum
#33
JOURNAL ARTICLE
Haiyan Zheng, Qian Wang, Feng Chen
As previously demonstrated, serum beta-human chorionic gonadotropin (β-hCG) is linked to identifying early gestational abnormalities. This research was aimed at investigating the correlation between serum β-hCG levels and thyroid metabolic function in pregnant women with hyperemesis gravidarum (HG). Ninety-one pregnant women with HG were selected as the study group and divided into early pregnancy (EP), mid-pregnancy (MP), and late pregnancy (LP) groups according to their gestational weeks, while 84 normal pregnant women were selected as the control group...
2023: Chinese Journal of Physiology
https://read.qxmd.com/read/37927644/cannabinoid-hyperemesis-encounters-after-medical-legalization-in-oklahoma
#34
JOURNAL ARTICLE
Randal Riha, Ryan Winchell, Danielle Safo, Joshua Gentges
Introduction Medical cannabis has recently become legal in Oklahoma. Cannabinoid hyperemesis syndrome (CHS) is severe nausea, vomiting, and often abdominal pain typically seen in heavy users of cannabis. The aim of this study is to determine whether emergency department (ED) diagnoses of CHS have increased after medical legalization. Methods We performed a retrospective chart review study of equivalent time periods prior to and after the first legal sales of medical cannabis in Oklahoma. Data were gathered from a single urban ED of adult patients with diagnosed or suspected CHS...
October 2023: Curēus
https://read.qxmd.com/read/37916005/retrospective-analysis-of-hyperemesis-gravidarum-and-its-psychological-impact-during-hospital-admission
#35
JOURNAL ARTICLE
Rania Gamal Anwar El-Skaan, Rehab Mohamed Abdelrahman, Ahmed Mohamed Abdelhamed Hassan
BACKGROUND: The aim of this study was to evaluate hyperemesis gravidarum in pregnant women and its psychological impact. METHODS: This retrospective study included 109 pregnant females suffering from hyperemesis gravidarum admitted during 2019-2020 at Maternity Ain shams university hospital. RESULTS: Disease severity and laboratory investigations such as Na and K levels ( P  = 0.007 and < 0.001, respectively) and serum creatinine level ( P  < 0...
October 2023: Journal of Obstetrics and Gynaecology of India
https://read.qxmd.com/read/37908576/gestational-transient-thyrotoxicosis-complicated-by-thyroid-storm-in-a-patient-with-hyperemesis-gravidarum
#36
Camila A Villavicencio, Alberto Franco-Akel, Regina Belokovskaya
We describe a patient with gestational transient thyrotoxicosis (GTT) associated with hyperemesis gravidarum (HG) in a twin gestation complicated by thyroid storm resulting in intrauterine fetal demise. GTT is a well-documented complication of the first trimester of pregnancy that may affect up to 60% of pregnancies with HG. Typically, GTT is not associated with unfavorable maternal or fetal outcomes and has a spontaneous resolution. Aside from supportive care, the use of antithyroid drugs (ATD) in GTT is not regularly recommended...
May 2023: JCEM Case Rep
https://read.qxmd.com/read/37900237/maternal-diaphragmatic-hernia-in-pregnancy-a-systematic-review-with-a-treatment-algorithm
#37
JOURNAL ARTICLE
Goran Augustin, Diana Kovač, Vesna Sokol Karadjole, Vendy Zajec, Mislav Herman, Pero Hrabač
BACKGROUND: Diaphragmatic hernia (DH) is extremely rarely described during pregnancy. Due to the rarity, there is no diagnostic or treatment algorithm for DH in pregnancy. AIM: To summarize and define the most appropriate diagnostic methods and therapeutic options for DH in pregnancy based on scarce literature. METHODS: Literature search of English-, German-, Spanish-, and Italian-language articles were performed using PubMed (1946-2021), PubMed Central (1900-2021), and Google Scholar...
September 26, 2023: World Journal of Clinical Cases
https://read.qxmd.com/read/37891710/treatments-for-hyperemesis-gravidarum-a-systematic-review
#38
REVIEW
Marie-Therese Vinnars, Maria Forslund, Ing-Marie Claesson, Annicka Hedman, Nathalie Peira, Hanna Olofsson, Emma Wernersson, Hanna Ulfsdottir
INTRODUCTION: Hyperemesis gravidarum affects 0.3%-3% of pregnant women each year and is the leading cause of hospitalization in early pregnancy. Previous systematic reviews of available treatments have found a lack of consistent evidence, and few studies of high quality. Since 2016, no systematic review has been conducted and an up-to date review is requested. In a recent James Lind Alliance collaboration, it was clear that research on effective treatments is a high priority for both patients and clinicians...
January 2024: Acta Obstetricia et Gynecologica Scandinavica
https://read.qxmd.com/read/37887695/childbearing-with-hypermobile-ehlers-danlos-syndrome-and-hypermobility-spectrum-disorders-a-large-international-survey-of-outcomes-and-complications
#39
JOURNAL ARTICLE
Gemma Pearce, Lauren Bell, Sally Pezaro, Emma Reinhold
One in 20 births could be affected by hypermobile Ehlers-Danlos syndrome or Hypermobility Spectrum Disorders (hEDS/HSD); however, these are under-diagnosed and lacking research. This study aimed to examine outcomes and complications in people childbearing with hEDS/HSD. A large online international survey was completed by women with experience in childbearing and a diagnosis of hEDS/HSD ( N = 947, total pregnancies = 1338). Data were collected on demographics, pregnancy and birth outcomes and complications...
October 21, 2023: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/37879293/hyperemesis-gravidarum-and-the-risk-of-childhood-cancer-a-case-control-study-in-denmark
#40
JOURNAL ARTICLE
Helen T Orimoloye, Chuanjie Deng, Johnni Hansen, Jorn Olsen, Chai Saechao, Beate Ritz, Julia E Heck
OBJECTIVE: Only a few studies have reported on the association between hyperemesis gravidarum and the risk of childhood cancer. We examined possible associations in this population-based study in Denmark. METHODS: Pediatric cancer cases (n = 6420) were ascertained from the Denmark Cancer Registry among children born between 1977 and 2013. Twenty-five controls were matched to each case by sex and birth date from the Central Person Registry (n = 160500)...
December 2023: Cancer Epidemiology
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