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hyperemesis pregnancy

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https://www.readbyqxmd.com/read/29630025/direct-percutaneous-endoscopic-jejunostomy-for-the-management-of-gastroparesis-in-pregnancy
#1
Sawan Vijay Rupani, William F Ergen, Frederick Weber, Shajan Peter
BACKGROUND: Providing meaningful nutrition in cases of refractory hyperemesis during pregnancy can be challenging; although intragastric enteral nutrition is the most common approach, it is contraindicated in certain cases and carries the risk of increased nausea and vomiting. CASE: A 36-year-old primigravid woman with a history of gastroparesis presented at 16 weeks of gestation with nausea and vomiting. With no improvement with conventional approaches and signs of malnutrition, a direct percutaneous endoscopic jejunostomy was placed...
April 6, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29599677/venom-immunotherapy-and-pregnancy
#2
Krzysztof Pałgan, Magdalena Żbikowska-Götz, Elżbieta Chrzaniecka, Zbigniew Bartuzi
Introductions: The efficiency of venom immunotherapy (VIT) has been well documented by many studies. However, the most important for VIT is safety, particularly for a pregnant woman and a fetus. Aim: To establish the influence of continuation of VIT on pregnant women and offspring. Material and methods: The 6 women became pregnant during a specific immunotherapy. We retrospectively analyzed the influence of the immunotherapy on any complications for the pregnant women and their infants...
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29563502/placenta-and-appetite-genes-gdf15-and-igfbp7-are-associated-with-hyperemesis-gravidarum
#3
Marlena S Fejzo, Olga V Sazonova, J Fah Sathirapongsasuti, Ingileif B Hallgrímsdóttir, Vladimir Vacic, Kimber W MacGibbon, Frederic P Schoenberg, Nicholas Mancuso, Dennis J Slamon, Patrick M Mullin
Hyperemesis gravidarum (HG), severe nausea and vomiting of pregnancy, occurs in 0.3-2% of pregnancies and is associated with maternal and fetal morbidity. The cause of HG remains unknown, but familial aggregation and results of twin studies suggest that understanding the genetic contribution is essential for comprehending the disease etiology. Here, we conduct a genome-wide association study (GWAS) for binary (HG) and ordinal (severity of nausea and vomiting) phenotypes of pregnancy complications. Two loci, chr19p13...
March 21, 2018: Nature Communications
https://www.readbyqxmd.com/read/29546743/secondary-adrenal-insufficiency-in-pregnancy-any-differences
#4
Stephan Petersenn
Secondary adrenal insufficiency may pose specific challenges during pregnancy. The interpretation of diagnostic tests is hindered by physiological adaptations of the HPA axis. Due the relevant increases in CBG, measurement of salivary cortisol may be preferable, but lacks sufficiently established cut-offs both for early-morning evaluation and during dynamic testing. Hydrocortisone should be used for replacement to avoid overexposure of the fetus, with dose adjustments according to clinical judgement. To account for increased free cortisol levels during the course of pregnancy, hydrocortisone may be increased by 5-7...
March 15, 2018: Minerva Endocrinologica
https://www.readbyqxmd.com/read/29516507/breast-cancer-risk-in-relation-to-history-of-preeclampsia-and-hyperemesis-gravidarum-prospective-analysis-in-the-generations-study
#5
Lauren B Wright, Minouk J Schoemaker, Michael E Jones, Alan Ashworth, Anthony J Swerdlow
Preeclampsia and hyperemesis are pregnancy complications associated with altered sex hormone levels. Previous studies suggest preeclampsia may be associated with a decreased risk of subsequent breast cancer and hyperemesis with an increased risk, but the evidence remains unclear. We used data from the Generations Study, a large prospective study of women in the United Kingdom, to estimate relative risks of breast cancer in relation to a history of preeclampsia and hyperemesis using Cox Regression adjusting for known breast cancer risk factors...
March 8, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29398518/hyperemesis-gravidarum-is-not-a-negative-contributing-factor-for-postpartum%C3%A2-bone-mineral-density
#6
Gulsum Uysal, Fulya Cagli, Hatice Akkaya, Hakan Nazik, Cigdem Karakukcu, Serap Sutbeyaz, Esra S Yilmaz
BACKGROUND: Hyperemesis gravidarum (HG), related to protracted vomiting and nausea, is a common cause of hospitalization during the first trimester of pregnancy. It can be accompanied by ketonuria, dehydration, and weight loss. Our aim was to investigate bone loss in patients with HG. METHODS: In our study, we investigated decreased bone mineral density (BMD)in a total of 79 patients (40 HG and 39 control) by means of dual energy X-ray absorptiometry (DEXA) measurements and laboratory parameters related to HG...
February 1, 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29390905/elevated-circulating-nitric-oxide-levels-correlates-with-enhanced-oxidative-stress-in-patients-with-hyperemesis-gravidarum
#7
Fatma Beyazit, Hakan Türkön, Eren Pek, Filiz Halici Ozturk, Mesut Ünsal
Since the biochemical and molecular mechanisms responsible for ongoing oxidative stress in hyperemesis gravidarum (HEG) patients have not yet been fully elucidated, the aim of this study was to evaluate the possible role of nitric oxide (NO), malondialdehyde (MDA) and other oxidative stress markers in the disease pathophysiology. Moreover, the relation between oxidative stress markers and Helicobacter pylori (H. pylori) infection was also investigated. Women with pregnancies complicated by HEG (n = 33) were compared with pregnant women without HEG (n = 30) and with healthy non-pregnant women (n = 31)...
February 1, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29385934/a-case-of-prolonged-hyperemesis-resulting-in-hepatorenal-failure-foetal-distress-and-neonatal-mortality
#8
Cemile Dayangan Sayan
Hyperemesis gravidarum is defined as a condition emerging during pregnancy, is prominent with severe nausea and vomiting, a water-electrolyte imbalance and liver-kidney function disorder and causes more than 5% loss of body weight. In cases of severe hyperemesis gravidarum, maternal morbidities such as water-electrolyte imbalance, hepatorenal failure, Wernicke's encephalopathy, splenic avulsion, oesophageal rupture, pneumothorax have been reported. We present a case of hyperemesis gravidarum, which continued until the third trimester and developed secondary hepatorenal failure, a water-electrolyte imbalance, intrauterine growth restriction, anhydramnios, foetal distress and neonatal mortality...
January 31, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29275391/intractable-hyperemesis-gravidarum-in-a-patient-with-type-1-diabetes
#9
Muhammad Fahad Arshad, Nasir Javed, Mohammad Bekhit
Hyperemesis gravidarum is not uncommon. Its pathogenies is multifactorial but not fully understood. We present a case of a middle class, Caucasian pregnant woman aged 24 years with coexisting type 1 diabetes, who had severe hyperemesis gravidarum from the sixth week of pregnancy and was resistant to all standard and off-the-label treatments raising questions about the pathogenesis of hyperemesis gravidarum. She was managed with a multidisciplinary approach and was supported with total parenteral nutrition till she had an emergency caesarean section in the 29th week of pregnancy...
December 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29227846/maternal-human-chorionic-gonadotrophin-concentrations-in-very-early-pregnancy-and-risk-of-hyperemesis-gravidarum-a-retrospective-cohort-study-of-4372-pregnancies-after-in-vitro-fertilization
#10
Johanne Dypvik, Andrea Lid Pereira, Tom Gunnar Tanbo, Anne Eskild
OBJECTIVE: We investigated the association of human chorionic gonadotrophin (hCG) concentrations on a fixed day in very early pregnancy with development of hyperemesis gravidarum. STUDY DESIGN: This retrospective cohort study included 3107 singleton and 1265 twin pregnancies after in vitro fertilization treated at Department of Reproductive Medicine, Rikshospitalet, Oslo University Hospital, Norway in the period 1996-2013. Maternal serum hCG concentrations was measured on day 12 after embryo transfer...
February 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29212865/the-placenta-controls-the-physiology-of-pregnancy-by-increasing-the-half-life-in-blood-and-receptor-activity-of-its-secreted-peptide-hormones
#11
REVIEW
Philip Lowry, Russell Woods
An efficient functioning placenta is essential for a healthy pregnancy and yet the way this is achieved has been the subject of much discussion and confusion, particularly with the occurrence of pathological conditions such as preeclampsia, morning sickness and hyperemesis/ptyalism gravidarum. We will attempt to explain the underlying physiology and the potential roles played by the placental tachykinins, neurokinin B and endokinin.
January 2018: Journal of Molecular Endocrinology
https://www.readbyqxmd.com/read/29178407/a-meta-analysis-of-the-association-between-helicobacter-pylori-h-pylori-infection-and-hyperemesis-gravidarum
#12
Qin Xiang Ng, Nandini Venkatanarayanan, Michelle Lee Zhi Qing De Deyn, Collin Yih Xian Ho, Yin Mo, Wee-Song Yeo
BACKGROUND: Hyperemesis gravidarum remains a common, distressing, and significant yet poorly understood disorder during pregnancy. The association between maternal Helicobacter pylori (H. pylori) infection and hyperemesis gravidarum has been increasingly recognized and investigated. This study thus aimed to provide an updated review and meta-analysis of the topic. METHODS: Using the search terms (H. pyloriOR Helicobacter ORHelicobacter pyloriOR infection) AND (pregnancy OR emesis OR hyperemesis gravidarum OR nausea OR vomiting), a preliminary search on the PubMed, Ovid, Web of Science, Google Scholar, and WanFang database yielded 372 papers published in English between January 1st, 1960 and June 1st, 2017...
February 2018: Helicobacter
https://www.readbyqxmd.com/read/29169898/hyperemesis-gravidarum-pregnancy-and-bone-loss
#13
EDITORIAL
Chang-Ching Yeh, Fa-Kung Lee, Peng-Hui Wang
No abstract text is available yet for this article.
November 20, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29135749/recurrence-rates-of-hyperemesis-gravidarum-in-pregnancy-a-systematic-review-protocol
#14
Caitlin Dean, Katrina Bannigan, Margaret O'Hara, Rebecca Painter, Jon Marsden
The quantitative objective of this review is to identify the recurrence rate of hyperemesis gravidarum (HG) in subsequent pregnancies.
November 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29123073/moderate-iodine-deficiency-among-pregnant-women-in-hong-kong-revisit-the-problem-after-two-decades
#15
W H Tam, R Sm Chan, M Hm Chan, L Y Yuen, L Li, M Mm Sea, J Woo
INTRODUCTION: A survey conducted during 2005 to 2007 by the Centre for Food Safety in Hong Kong suggested that only 5% of the local population had a sufficient dietary intake of iodine. The study, however, was limited as biochemical data (ie urinary iodine concentration) were lacking. Pregnant women are vulnerable to iodine deficiency because of their increased requirement. Recent studies have shown that iodine deficiency in early pregnancy is associated with poorer cognitive development in early childhood...
December 2017: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/29066809/obstetric-outcomes-in-pregnant-women-with-and-without-depression-population-based-comparison
#16
Hui-Chun Huang, Fung-Chang Sung, Pei-Chun Chen, Cherry Yin-Yi Chang, Chih-Hsin Muo, Huei-Sheng Shiue, Jian-Pei Huang, Tsai-Chung Li, Ya-Ling Tzeng, Shu-I Wu
This study used insurance claims data to evaluate obstetric outcomes in pregnant women with and without depression because population study for Asian women on the issue is limited. We identified 5,064 women with depression at pregnancy in 2005-2013, and 20,024 pregnant women without depression, frequency matched by age, pregnant year and parity. Obstetric events during pregnancy and deliveries were evaluated. The depression group had more events than comparisons for hyperemesis (39.3 vs. 35.5%), abortion (3...
October 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29028104/the-influence-of-ovulation-induction-and-assisted-conception-on-maternal-and-perinatal-outcomes-of-twin-pregnancies
#17
G Bordi, A D'Ambrosio, I Gallotta, L Di Benedetto, A Frega, F Torcia, M Schimberni, M Bonito, D Caserta
OBJECTIVE: To compare obstetrical and neonatal outcomes of twin pregnancies conceived via assisted reproductive technology (ART) with those of naturally conceived ones and to investigate the influence of the ART procedure type on these parameters. PATIENTS AND METHODS: This observational study included 450 ART and 647 spontaneous twin pregnancies delivered over 15 years at a single university-based hospital of Rome, Italy. Logistic and linear regression models adjusted for confounding factors were used to evaluate the effect of ART and the type of assisted conception (IVF/ICSI, ovulation induction ± intrauterine insemination, egg/embryo donation) on maternal and perinatal outcomes...
September 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29025533/negative-%C3%AE-hcg-and-molar-pregnancy-the-hook-effect
#18
Isabel Lobo Antunes, Joana Curado, Ana Quintas, Alcides Pereira
Molar pregnancy, included in gestational trophoblastic disease, is a benign pathology with ability to metastasize, usually occurring with excessively high βhCG levels. Clinical scenario is usually a woman in extremes of reproductive age presenting with amenorrhoea, pain and vaginal blood loss; signs derived from high βhCG levels may be present (hyperthyroidism, hyperemesis). Diagnosis is based on a positive pregnancy test - usually a qualitative urinary test. The limitation of this test results from its inability to become positive in presence of markedly high levels of βhCG, saturating the antigens used - known as the 'hook effect'...
September 29, 2017: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/29016589/risk-factors-associated-with-low-birth-weight-among-deliveries-at-bharatpur-hospital
#19
Kamal Prasad Kandel, Sindhu Kafle
BACKGROUND: Babies with a birth weight of less than 2500 grams, irrespective of the period of their gestation are termed as Low Birth Weight (LBW) babies. Despite consistent efforts to improve the quality of maternal and child health, more than twenty million low birth-weight (LBW) babies are born every year throughout the world. Though, the health situation of Nepal has improved substantially over the years, the low birth-weight (LBW) rate is still high. The objective of this study was to assess the proportion of low birth weight and identify the associated factors for low birth weight in a live born infant among the institutionally delivered newborns...
September 8, 2017: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/28984372/adverse-maternal-and-birth-outcomes-in-women-admitted-to-hospital-for-hyperemesis-gravidarum-a-population-based-cohort-study
#20
Linda Fiaschi, Catherine Nelson-Piercy, Jack Gibson, Lisa Szatkowski, Laila J Tata
BACKGROUND: Evidence for risks of adverse maternal and birth outcomes in women with hyperemesis gravidarum (HG) is predominantly from small studies, unknown, or conflicting. METHODS: A population-based cohort study using secondary health care records (Hospital Episode Statistics covering all of England from 1997 to 2012) was used to calculate odds ratios (OR) with 99% confidence intervals (CI) for the association between HG hospital admission and adverse outcomes, adjusting for maternal and pregnancy confounders...
January 2018: Paediatric and Perinatal Epidemiology
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