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https://www.readbyqxmd.com/read/28637271/logical-issues-with-the-pressure-natriuresis-theory-of-chronic-hypertension
#1
Theodore W Kurtz, Stephen E DiCarlo, R Curtis Morris
The term "abnormal pressure natriuresis" refers to a subnormal effect of a given level of blood pressure (BP) on sodium excretion. It is widely believed that abnormal pressure natriuresis causes an initial increase in BP to be sustained. We refer to this view as the "pressure natriuresis theory of chronic hypertension." The proponents of the theory contend that all forms of chronic hypertension are sustained by abnormal pressure natriuresis, irrespective of how hypertension is initiated. This theory would appear to follow from "the three laws of long-term arterial pressure regulation" stated by Guyton and Coleman more than 3 decades ago...
December 1, 2016: American Journal of Hypertension
https://www.readbyqxmd.com/read/28628521/experiences-of-acute-pain-in-children-who-present-to-a-healthcare-facility-for-treatment-a-systematic-review-of-qualitative-evidence
#2
Nicole Pope, Mary Tallon, Ruth McConigley, Gavin Leslie, Sally Wilson
BACKGROUND: Pain is a universal and complex phenomenon that is personal, subjective and specific. Despite growing knowledge in pediatric pain, management of children's pain remains sub-optimal and is linked to negative behavioral and physiological consequences later in life. As there is no synthesis of these studies, it was timely to undertake a systematic review. OBJECTIVES: To identify, evaluate and synthesize the existing qualitative evidence on children's experiences of acute pain, including pain management, within a healthcare facility...
June 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28622007/starting-off-on-the-best-foot-a-review-of-message-framing-and-message-tailoring-and-recommendations-for-the-comprehensive-messaging-strategy-for-sustained-behavior-change
#3
J Paige Pope, Luc Pelletier, Camille Guertin
Health promotion programs represent a salient means through which physical activity promoters can cultivate positive health behavior change and maintenance. The messages communicated within these programs serve as an essential component as they are often used to convey valuable information, resources, or tools that facilitate health behavior initiation and sustained engagement. Identifying the most effective way to communicate health promotion information is, therefore, of considerable importance to ensuring that people not only attend to these messages, but also connect with and internalize the information conveyed within them...
June 16, 2017: Health Communication
https://www.readbyqxmd.com/read/28605243/intimate-partner-violence-and-its-resolution-among-mexican-americans
#4
Deborah Finfgeld-Connett
Intimate partner violence (IPV) affects the mental and physical health of Mexican women in the United States, and culture is thought to play a role in its prevention and resolution. Qualitative investigations are ideal for explicating context-specific aspects of these phenomena. Thus, a systematic review of 19 primary qualitative research reports was conducted to clearly articulate the process of IPV and its resolution among Mexican American women. Based on the findings, IPV is fueled by aspects of Mexican culture, and barriers exist that make its resolution challenging...
June 2017: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/28601242/kinematic-models-of-lower-limb-joints-for-musculo-skeletal-modelling-and-optimization-in-gait-analysis
#5
REVIEW
Alberto Leardini, Claudio Belvedere, Fabrizio Nardini, Nicola Sancisi, Michele Conconi, Vincenzo Parenti-Castelli
Kinematic models of lower limb joints have several potential applications in musculoskeletal modelling of the locomotion apparatus, including the reproduction of the natural joint motion. These models have recently revealed their value also for in vivo motion analysis experiments, where the soft-tissue artefact is a critical known problem. This arises at the interface between the skin markers and the underlying bone, and can be reduced by defining multibody kinematic models of the lower limb and by running optimization processes aimed at obtaining estimates of position and orientation of relevant bones...
May 22, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28598746/core-principles-of-assessment-in-competency-based-medical-education
#6
Jocelyn Lockyer, Carol Carraccio, Ming-Ka Chan, Danielle Hart, Sydney Smee, Claire Touchie, Eric S Holmboe, Jason R Frank
The meaningful assessment of competence is critical for the implementation of effective competency-based medical education (CBME). Timely ongoing assessments are needed along with comprehensive periodic reviews to ensure that trainees continue to progress. New approaches are needed to optimize the use of multiple assessors and assessments; to synthesize the data collected from multiple assessors and multiple types of assessments; to develop faculty competence in assessment; and to ensure that relationships between the givers and receivers of feedback are appropriate...
June 2017: Medical Teacher
https://www.readbyqxmd.com/read/28576193/hindfoot-arthrodesis-for-the-elective-and-posttraumatic-foot-deformity
#7
REVIEW
John J Stapleton, Thomas Zgonis
Triple (talonavicular, subtalar, and calcaneocuboid) joint arthrodesis and most recently double (talonavicular and subtalar) joint arthrodesis have been well proposed in the literature for surgical repair of the elective, posttraumatic, and/or neuropathic hindfoot deformities. The articulation of the hindfoot with the ankle and midfoot is multiaxial, and arthrodesis of these joints can significantly alter the lower extremity biomechanical manifestations by providing anatomic correction and alignment. This article reviews the indications and preoperative planning for some of the most common procedures to address the hindfoot deformity...
July 2017: Clinics in Podiatric Medicine and Surgery
https://www.readbyqxmd.com/read/28566407/pelvic-reconstruction-following-resection-of-malignant-bone-tumours-using-a-stemmed-acetabular-pedestal-cup
#8
C Hipfl, C Stihsen, S E Puchner, A Kaider, M Dominkus, P T Funovics, R Windhager
AIMS: Pelvic reconstruction after the resection of a tumour around the acetabulum is a challenging procedure due to the complex anatomy and biomechanics. Several pelvic endoprostheses have been introduced, but the rates of complication remain high. Our aim was to review the use of a stemmed acetabular pedestal cup in the management of these patients. PATIENTS AND METHODS: The study involved 48 patients who underwent periacetabular reconstruction using a stemmed pedestal cup (Schoellner cup; Zimmer Biomet Inc...
June 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28562800/guide-of-attributes-of-the-nurse-s-political-competence-a-methodological-study
#9
Wesley Soares de Melo, Paulo Jorge Ferreira de Oliveira, Flávia Paula Magalhães Monteiro, Francisca Carla Dos Angelos Santos, Maria Janaína Nogueira da Silva, Carolina Jimenez Calderon, Lilian Nara Amaral da Fonseca, Ana Adélia Chaves Simão
Objective: To build and validate a guide of attributes of the nurse's political competence. Method: Methodological research. This study comprised the construction of the instrument through literature review; experts validation of pre-established attributes for composing the guide; and clinical validation in the nurses work environment/reality. The data collection took place in the months from August to October 2014, and the analysis was based on the content analysis of Bardin and use of Epi info 3...
May 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28562126/a-systematic-literature-review-of-methods-of-incorporating-mortality-in-cost-effectiveness-analyses-of-lipid-lowering-therapies
#10
Jesse D Ortendahl, Amanda L Harmon, Tanya G K Bentley, Michael S Broder
AIMS: Cost effectiveness analysis (CEA) is a useful tool for estimating the value of an intervention in relation to alternatives. In cardiovascular disease (CVD), CEA is especially important, given the high economic and clinical burden. One key driver of value is CVD mortality prevention. However, data used to inform CEA parameters can be limited, given the difficulty in demonstrating statistically significant mortality benefit in randomized clinical trials (RCTs), due in part to the frequency of fatal events and limited trial durations...
July 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28545371/a-psycho-behavioral-perspective-on-modelling-obsessive-compulsive-disorder-ocd-in-animals-the-role-of-context
#11
De Wet Wolmarans, Dan J Stein, Brian H Harvey
Obsessive-compulsive disorder is a heterogeneous and debilitating condition, characterized by intrusive thoughts and compulsive repetition. Animal models of OCD are important tools that have the potential to contribute significantly to our understanding of the condition. Although there is consensus that pre-clinical models are valuable in elucidating the underlying neurobiology in psychiatric disorders, the current paper attempts to prompt ideas on how interpretation of animal behavior can be expanded upon to more effectively converge with the human disorder...
May 23, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28529655/scfe-clinical-aspects-diagnosis-and-classification
#12
M B Millis
PURPOSE: This article seeks to improve treatment outcomes in slipped capital femoral epiphysis (SCFE) by outlining advances in diagnosis, understanding of pathomechanics, and mechanically-based classification. METHODS: Review of clinical experience with SCFE at our high-volume centre, interaction with other clinical experts, and literature review has allowed a current perspective to be articulated. RESULTS: SCFE remains an important clinical problem, with late diagnosis still frequent...
April 2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/28511123/dismissing-the-goals-a-comparison-of-four-goal-dismissive-goal-free-evaluations
#13
Brandon W Youker, Ken Ford, Nicholas Bayer
This article provides a descriptive review of four goal-free evaluations (GFE). GFE is an evaluation model where the evaluator conducts the evaluation without knowledge of or reference to the evaluand's stated goals. The four non-randomly sampled evaluation approaches represent articulated evaluation models in which the evaluators ignore the goals of the intervention or project. Data collection consisted of document analyses supplemented by semi-structured interviews with the models' creators. The findings from these case studies include descriptions of the evaluation models, the models' relationship to GFE, and eight commonalities shared among the four models...
October 2017: Evaluation and Program Planning
https://www.readbyqxmd.com/read/28493934/taking-stock-of-the-social-determinants-of-health-a-scoping-review
#14
Kelsey Lucyk, Lindsay McLaren
BACKGROUND: In recent decades, the social determinants of health (SDOH) has gained increasing prominence as a foundational concept for population and public health in academic literature and policy documents, internationally. However, alongside its widespread dissemination, and in light of multiple conceptual models, lists, and frameworks, some dilution and confusion is apparent. This scoping review represents an attempt to take stock of SDOH literature in the context of contemporary population and public health...
2017: PloS One
https://www.readbyqxmd.com/read/28483239/the-efficacy-and-safety-of-the-flexible-fiber-co2-laser-delivery-system-in-the-endoscopic-management-of-pediatric-airway-problems-our-long-term-experience
#15
Gi Soo Lee, Alexandra Irace, Reza Rahbar
OBJECTIVE: To report the use of flexible fiber CO2 laser in the endoscopic management of pediatric airway cases. METHODS: A retrospective review was conducted of patients who underwent CO2 laser-assisted airway procedures between September 2007 and January 2014 at a tertiary pediatric hospital. RESULTS: Sixty-eight patients underwent 80 procedures utilizing flexible fiber CO2 laser. Procedures included supraglottoplasty (n = 32), laryngeal cleft repair (type I [n = 10], type II [n = 7], type III [n = 6]), suprastomal granuloma excision (n = 6), cordotomy (n = 4), laryngeal neurofibroma excision (n = 4), laryngeal granulomatous mass excision (n = 1), subglottic stenosis excision (n = 6), division of glottic web (n = 2), subglottic cyst excision (n = 1), and supraglottic biopsy (n = 1)...
June 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28462215/condylar-constrained-system-in-primary-total-knee-replacement-our-experience-and-literature-review
#16
Luigi Sabatini, Salvatore Risitano, Lorenzo Rissolio, Andrea Bonani, Francesco Atzori, Alessandro Massè
BACKGROUND: Constrained condylar knee (CCK) prosthesis are common used for revision surgery but can also help surgeons to improve implant stability in primary knee arthroplasty, in fact in severe knee arthrosis with serious deformity associated with a significant instability a more constrained articulation is required. With introduction of second generation of semi-constrained prosthesis, rate of complication is real decreased and a good survival rate and functional score results is showed...
March 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28452673/improving-mental-health-in-the-community-outcome-evaluation-of-a-geriatric-mental-health-day-treatment-service
#17
Christine A Knight, Richard M Alarie
OBJECTIVES: This program evaluation reviewed the outcomes of a new 10-week multi-modal mental health day treatment program for elderly clients with mood and anxiety disorders. METHODS: A retrospective chart review of clients admitted during the first 3 years of the program (N = 255) was conducted. Paired sample t-tests were used to compare admission and discharge data. Focus groups were run with clients who attended the program during the previous months, to delineate the strengths of the program and to identify areas for improvement...
March 2017: Clinical Gerontologist
https://www.readbyqxmd.com/read/28450205/nucleic-acid-combinations-a-new-frontier-for-cancer-treatment
#18
REVIEW
Remant Bahadur K C, Bindu Thapa, Juliana Valencia-Serna, Hamidreza Montezari Aliabadi, Hasan Uludağ
The emerging molecular understanding of cancer cell behavior is leading to increasing possibilities to control unchecked cell growth and metastasis. On the other hand, development of multifunctional drug carriers at the 'nano'-scale is providing exciting new therapeutic strategies in clinical management of cancer beyond the conventional cytotoxic drugs. A new frontier in this regard is the combinational use of complementary agents based on nucleic acids to overcome the limitations of conventional therapy. The existence of tightly-integrated cross-talk through multiple signaling and effector pathways have been appreciated for some time, and the plasticity of such a network to overcome one-dimensional intervention is stimulating development of combinational therapy...
June 28, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28449598/using-grade-as-a-framework-to-guide-research-on-the-sexual-and-reproductive-health-and-rights-srhr-of-women-living-with-hiv-methodological-opportunities-and-challenges
#19
Nandi Siegfried, Manjulaa Narasimhan, Caitlin E Kennedy, Alice Welbourn, Anandi Yuvraj
In March 2016, WHO reviewed evidence to develop global recommendations on the sexual and reproductive health and rights (SRHR) of women living with HIV. Systematic reviews and a global survey of women living with HIV informed the guideline development decision-making process. New recommendations covered abortion, Caesarean section, safe disclosure, and empowerment and self-efficacy interventions. Identification of key research gaps is part of the WHO guidelines development process, but consistent methods to do so are lacking...
April 27, 2017: AIDS Care
https://www.readbyqxmd.com/read/28429302/ethics-guidelines-in-environmental-epidemiology-their-development-and-challenges-we-face
#20
REVIEW
Shira Kramer, Colin L Soskolne
PURPOSE OF REVIEW: This review integrates historical developments and key events in bringing ethics into epidemiology in general and into environmental epidemiology in particular. The goal is to provide context for and discern among the various approaches and motivations that drive the need for ethical conduct in support of the public interest. RECENT FINDINGS: The need for ethics guidelines in epidemiology is different from developments in other biomedical-related fields by virtue of its focus on populations rather than on individuals...
April 20, 2017: Current Environmental Health Reports
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