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Waters PJ

Khaled S Abdlekawy, Ahmed M Donia, Fawzy Elbarbry
BACKGROUND: The package leaflet for dapoxetine, an effective treatment for premature ejaculation, includes a strict warning against coadministration with drugs or herbal remedies that strongly induce or inhibit the activity of Cytochrome P450 (CYP) 3A4 enzyme. OBJECTIVE: To assess the effects of multiple daily consumption of grapefruit juice (GFJ) and pomegranate juice (PJ) on the pharmacokinetics of dapoxetine, we conducted an open-label, three-way crossover study in 12 healthy subjects using midazolam as a probe substrate for CYP3A4...
June 13, 2016: European Journal of Drug Metabolism and Pharmacokinetics
S M Teichmann, F Silva, S L Cousin, M Hemmer, J Biegert
Attosecond light pulses in the extreme ultraviolet have drawn a great deal of attention due to their ability to interrogate electronic dynamics in real time. Nevertheless, to follow charge dynamics and excitations in materials, element selectivity is a prerequisite, which demands such pulses in the soft X-ray region, above 200 eV, to simultaneously cover several fundamental absorption edges of the constituents of the materials. Here, we experimentally demonstrate the exploitation of a transient phase matching regime to generate carrier envelope controlled soft X-ray supercontinua with pulse energies up to 2...
2016: Nature Communications
Ahmad Husari, Yasmine Hashem, Hala Bitar, Ghassan Dbaibo, Ghazi Zaatari, Marwan El Sabban
BACKGROUND: Cigarette smoke (CS) increases oxidative stress (OS) in the lungs. Pomegranate juice (PJ) possesses potent antioxidant activities, attributed to its polyphenols. This study investigates the effects of PJ on the damaging effects of CS in an animal model and on cultured human alveolar cells (A549). METHODS: Male C57BL/6J mice were divided into the following groups: Control, CS, CS + PJ, and PJ. Acute CS exposure was for 3 days, while chronic exposure was for 1 and 3 months (5 days of exposure/week)...
2016: International Journal of Chronic Obstructive Pulmonary Disease
E Fuster-Muñoz, E Roche, L Funes, P Martínez-Peinado, J M Sempere, N Vicente-Salar
OBJECTIVE: The aim of the present study was to assess the effects of pomegranate juice on the level of oxidative stress in the blood of endurance-based athletes. Pomegranate juice is rich in polyphenols, conferring it a higher antioxidant capacity than other beverages with polyphenolic antioxidants. METHODS: A randomized double-blind, multicenter trial was performed in athletes from three different sport clubs located in southeastern of Spain. Plasma oxidative stress markers (protein carbonyls and malondialdehyde [MDA]) as well as C-reactive protein and sE-selectin were measured...
May 2016: Nutrition
Henriette M C Azeredo, Rosario Morrugares-Carmona, Nikolaus Wellner, Kathryn Cross, Balazs Bajka, Keith W Waldron
The influence of pomegranate juice (PJ, replacing water as solvent) and citric acid (CA) on properties of pectin films was studied. PJ provided the films with a bright red color, and acted as a plasticizer. Increasing PJ/water ratio from 0/100 to 100/0 resulted in enhanced elongation (from 2% to 20%), decreased strength (from 10 to <2 MPa) and modulus (from 93 to <10 MPa), increased water vapor permeability (WVP, from 3 to 9, and decreased insoluble matter (IM, from 35% to 24%)...
May 1, 2016: Food Chemistry
Prabukumar Seetharaman, Kamal Sarma, Grinson George, Pandian Krishnan, S Dam Roy, Kiruba Sankar
The impact of coastal pollution was studied using edible oysters, Crassostrea rivularis as an indicator at two sites viz., North Wandoor (NW) and Phoenix Jetty (PJ) in Port Blair, Andaman. The hydrographic parameters showed that nitrite, nitrate and phosphate concentration were less and dissolved oxygen were more at NW compared to PJ. The oysters were collected from the study sites and biochemical, microbial, mineral profiles and ATPase activities were estimated. ATPase activity was inhibited in the gill tissue of oysters (p<0...
November 2015: Bulletin of Environmental Contamination and Toxicology
James Forde, Francis X O'Beirn, Jack Pj O'Carroll, Adrian Patterson, Robert Kennedy
A considerable number of Ireland's shellfish production areas co-occur with or are adjacent to Natura 2000 sites which are protected under European legislation. To investigate the general interaction between trestle oyster cultivation and the surrounding intertidal environment, six sites were selected within designated Natura 2000 sites. At each trestle site three Treatment areas were sampled. One Treatment area corresponded to potential impacts associated with cultivation activities occurring at trestle structures (designated the Trestle Treatment) while one Treatment area corresponded to potential impacts due to cultivation activities occurring along access routes (the Access Treatment)...
June 15, 2015: Marine Pollution Bulletin
Karol Hensel, Katarína Kučerová, Barbora Tarabová, Mário Janda, Zdenko Machala, Kaori Sano, Cosmin Teodor Mihai, Mitică Ciorpac, Lucian Dragos Gorgan, Roxana Jijie, Valentin Pohoata, Ionut Topala
Atmospheric pressure DC-driven self-pulsing transient spark (TS) discharge operated in air and pulse-driven dielectric barrier discharge plasma jet (PJ) operated in helium in contact with water solutions were used for inducing chemical effects in water solutions, and the treatment of bacteria (Escherichia coli), mammalian cells (Vero line normal cells, HeLa line cancerous cells), deoxyribonucleic acid (dsDNA), and protein (bovine serum albumin). Two different methods of water solution supply were used in the TS: water electrode system and water spray system...
2015: Biointerphases
Pascal Vilain, Frédéric Pagès, Xavier Combes, Pierre-Jean Marianne Dit Cassou, Katia Mougin-Damour, Yves Jacques-Antoine, Laurent Filleul
INTRODUCTION: On January 2, 2014, Cyclone Bejisa struck Reunion Island (France). This storm led to major material damages, such as power outages, disturbance of drinking water systems, road closures, and the evacuation of residents. In this context, the Regional Office of French Institute for Public Health Surveillance in Indian Ocean (Cire OI) set up an epidemiological surveillance in order to describe short-term health effects of the cyclone. METHODS: The assessment of the health impact was based mainly on a syndromic surveillance system, including the activity of all emergency departments (EDs) and the Emergency Medical Service (EMS) of the island...
April 2015: Prehospital and Disaster Medicine
Xiangming Ji, Anee Usman, Nurul H Razalli, Ravigadevi Sambanthamurthi, Smiti V Gupta
BACKGROUND: Oil palm phenolics (OPP) or Palm Juice (PJ), a water soluble extract from the palm fruit (Elaies guineensis) has been documented to have anti-carcinogenic activities in various cancer types. MATERIALS AND METHODS: To investigate OPP effects in pancreatic cancer (PaCa) cells, two PaCa cell lines (PANC-1 and BxPC-3) were treated with different OPP doses. The anti-proliferative, apoptotic and anti-invasive properties of OPP were evaluated using MTS, cytoplasmic histone-DNA fragmentation and matrigel invasive assays, respectively...
January 2015: Anticancer Research
Bp Cunkelman, Ey Chen, Aa Petryk, Ja Tate, Sg Thappa, Rj Collier, Pj Hoopes
Treatments of the post-operative surgical bed have proven appealing as the majority of cancer recurrence following tumor resection occurs at the tumor margin. A novel, biodegradable pullulan-based gel infused with magnetic iron oxide nanoparticles (IONP) is presented here for surgical bed administration followed by hyperthermia therapy via alternating magnetic field (AMF) activation. Pullulan is a water soluble, film-forming starch polymer that degrades at the postoperative wound site to deliver the IONP payload, targeting the remaining cancer cells...
February 26, 2013: Proceedings—Society of Photo-Optical Instrumentation Engineers
Sm Cassim, Aj Giustini, Aa Petryk, Ra Strawbridge, Pj Hoopes
: It is established that heat can enhance the effect of radiation cancer treatment. Due to the ability to localize thermal energy using nanoparticle hyperthermia, as opposed to other, less targeted, hyperthermia modalities, it appears such enhancement could be accomplished without complications normally associated with systemic or regional hyperthermia. This study employs non-curative (suboptimal), doses of heat and radiation, in an effort to determine the therapeutic enhancement potential for IONP hyperthermia and radiation...
February 23, 2009: Proceedings—Society of Photo-Optical Instrumentation Engineers
Ahmad Husari, Aline Khayat, Hala Bitar, Yasmine Hashem, Alain Rizkallah, Ghazi Zaatari, Marwan El Sabban
BACKGROUND: Hyperoxia triggers the release of toxic reactive oxygen species (ROS). Pomegranate Juice (PJ) is a rich source of potent antioxidants. We assessed the effects of PJ supplementation on Acute Lung Injury (ALI) in adult rats exposed to hyperoxia for 5 days. METHODS: Adult rats were divided into four different groups: control, hyperoxia, hyperoxia + PJ and PJ. Animals were placed in chambers containing either room air or oxygen above 95% for a total of 5 days...
2014: BMC Research Notes
Nuzhath Tajuddin, Kwan-Hoon Moon, S Alex Marshall, Kimberly Nixon, Edward J Neafsey, Hee-Yong Kim, Michael A Collins
Evidence that brain edema and aquaporin-4 (AQP4) water channels have roles in experimental binge ethanol-induced neurodegeneration has stimulated interest in swelling/edema-linked neuroinflammatory pathways leading to oxidative stress. We report here that neurotoxic binge ethanol exposure produces comparable significant effects in vivo and in vitro on adult rat brain levels of AQP4 as well as neuroinflammation-linked enzymes: key phospholipase A2 (PLA2) family members and poly (ADP-ribose) polymerase-1 (PARP-1)...
2014: PloS One
Pj Lally, Ss Pauliah, Dl Price, A Bainbridge, S Addison, A Soe, S Pattnayak, P Satodia, Sc Wayte, E Ng'andwe, P Clarke, G Johnson, S Harigopal, Pt English, Lj Abernethy, Ma Turner, J Cheong, S Shankaran, Eb Cady, S Thayyil
BACKGROUND: Early cerebral proton magnetic resonance spectroscopy (MRS) predicts medium-term outcomes in neonatal encephalopathy (NE). Metabolite peak-area ratios are most commonly used for prognosis, but conflate pathological information from different metabolites. N-acetylaspartate (NAA) is predominantly neuronal and neuronal loss should result in reduced NAA absolute-concentration ([NAA]). Thus, thalamic [NAA] should offer significant prognostic value but is difficult to measure in a clinical setting...
June 2014: Archives of Disease in Childhood. Fetal and Neonatal Edition
Pj Lally, Dl Price, A Bainbridge, Ss Pauliah, P Satodia, Sc Wayte, L Abernethy, M Turner, An Basheer, A Alavi, O Kirmi, B Jones, S Shankaran, Eb Cady, S Thayyil
BACKGROUND: Proton magnetic resonance spectroscopy (MRS) has high prognostic value in hypoxic ischaemic encephalopathy (HIE), however its multi-centre application is limited by inconsistencies between scanners and protocols. N-acetylaspartate (NAA) is predominantly neuronal: cerebral NAA concentration may be a more reliable HIE-severity biomarker than lactate/NAA. OBJECTIVE: To quantify the inter-site and inter-subject variability of NAA concentration measurements...
June 2014: Archives of Disease in Childhood. Fetal and Neonatal Edition
Kevin C Miller
CONTEXT: Some athletes ingest pickle juice (PJ) or mustard to treat exercise-associated muscle cramps (EAMCs). Clinicians warn against this because they are concerned it will exacerbate exercise-induced hypertonicity or cause hyperkalemia. Few researchers have examined plasma responses after PJ or mustard ingestion in dehydrated, exercised individuals. OBJECTIVE: To determine if ingesting PJ, mustard, or deionized water (DIW) while hypohydrated affects plasma sodium (Na(+)) concentration ([Na(+)]p), plasma potassium (K(+)) concentration ([K(+)]p), plasma osmolality (OSMp), or percentage changes in plasma volume or Na(+) content...
May 2014: Journal of Athletic Training
Sara Tavassoli-Hojjati, Elham Aliasghar, Fatemeh Ahmadian Babaki, Fatemeh Emadi, Maliheh Parsa, Shohreh Tavajohi, Maryam Ahmadyar, Seyed Nasser Ostad
OBJECTIVE: There is evidence indicating that pomegranate juice contains many of the essential properties necessary to retain cell viability and cell proliferation. These properties indicate that pomegranate juice is a suitable storage medium for avulsed teeth. However, this idea has not yet been tested. In this study, the capacity of pomegranate juice (PJ) as a storage medium for retaining avulsed teeth was evaluated. MATERIALS AND METHODS: PDL fibroblasts were obtained from healthy human premolars and cultured in Dulbecco's Modified Eagle's Medium (DMEM)...
March 2014: Journal of Dentistry of Tehran University of Medical Sciences
Walmor C De Mello
UNLABELLED: The influence of hypertonic solution on dye coupling was investigated in cell pairs isolated from the left ventricle of adult Sprague Dawley rats.The hypertonic solution together with Lucifer Yellow CH, were dialyzed into one cell of the pair using the whole cell clamp tecnique, and the diffusion of dye in the dialyzed as well as in non-dialyzed cell, was followed by measuring the intensity of fluorescence in both cells as a function of time.The results indicated that: (1) Lucifer Yellow CH dialyzed into one cell of the pair diffuses easily into the nondialyzed cell through gap junctions; (2) the intracellular dialysis of an hypertonic solution into one cell of the pair, increases the area of the dialyzed cell and reduced the area of the non-dialyzed cell suggesting intercellular movement of water; (3) the hypertonic solution dialyzed into one cell of the pair abolished the dye coupling; (4) the gap junction permeability (Pj) estimated before and after administration of hypertonic solution showed an appreciably decrease of Pj; (5) angiotensin (1-7) (Ang (1-7) (10-9M) administered to the bath re-established the dye coupling abolished by hypertonic solution and reduced the cell area; (6) the effect of Ang (1-7) was related to the activation of Mas receptor and was dependent on the activation of PKA...
May 1, 2014: Experimental Cell Research
Alice J DeSimone, Thomas M Orlando
Photodissociation of amorphous solid water (ASW) deposited on a thinly oxidized copper substrate at 82 K was studied by measuring O((3)PJ=2,1,0) photoproducts detected with resonance-enhanced multiphoton ionization. For each spin-orbit state, the oxygen atom time-of-flight spectrum was measured as a function of H2O exposure, which is related to ice thickness, and 157-nm irradiation time. Four Maxwell-Boltzmann distributions with translational temperatures of 10,000 K, 1800 K, 400 K, and 82 K were found to fit the data...
March 7, 2014: Journal of Chemical Physics
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