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Halo nevus

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https://www.readbyqxmd.com/read/29133759/factors-associated-with-development-of-vitiligo-in-patients-with-halo-nevus
#1
Hui Zhou, Liang-Cai Wu, Mu-Kai Chen, Qi-Man Liao, Ren-Xiang Mao, Jian-De Han
BACKGROUND: Halo nevus (HN) has been shown to be associated with vitiligo, but no standard signs are currently available to identify HN patients at risk of vitiligo, and the relevant data obtained in previous studies are somewhat conflicting. This study aimed to identify factors affecting the presence of vitiligo in HN patients. METHODS: We performed a retrospective study on consecutive patients with HN at the First Affiliated Hospital of Sun Yat-sen University between January 2011 and December 2016...
November 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28954104/the-recurrent-nevus-phenomenon
#2
Rafaella Daboit Castagna, Juliana Mazzoleni Stramari, Raíssa Massaia Londero Chemello
Recurrent melanocytic nevus is a proliferation of melanocytes arising from a melanocytic nevus removed partially. Asymmetry and irregular pigmentation may lead to misdiagnosis of melanoma. We report a patient presented with a lesion on the lower abdomen, which was removed by shave excision. Anatomopathological examination revealed an intradermal melanocytic nevus. Two months later, a new irregular hyperpigmented lesion appeared in the surgical scar. Histopathology of the excisional biopsy revealed a recurrent melanocytic nevus...
July 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28880143/-an-infant-with-a-nevus-on-the-upper-leg
#3
M E Weijns, M Houtappel
We present a 4-month-old infant with an eczematous halo around a congenital melanocytic nevus. After diagnostic excision, histopathologic examination revealed a Meyerson's nevus. This is a benign skin tumour that may show clinical signs of melanoma. It is therefore important to include Meyerson's nevus in the differential diagnosis of melanoma.
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28580411/recurrent-halo-nevus-dermoscopy-and-confocal-microscopy-features
#4
Ana Carolina Porto, Tatiana Pinto Blumetti, Raquel de Paula Ramos Castro, Clovis Antônio Lopes Pinto, Adriana Silveira Pessoa Mendes, João Pedreira Duprat Neto, Gisele Gargantini Rezze, Juliana Casagrande Tavoloni Braga
No abstract text is available yet for this article.
May 2017: JAAD Case Reports
https://www.readbyqxmd.com/read/28447350/dermoscopy-pathology-relationship-in-seborrheic-keratosis
#5
REVIEW
Akane Minagawa
Making a definitive diagnosis of seborrheic keratosis (SK) can be challenging for the naked eye due to its wide variation in clinical features. Fortunately, however, most cases of SK exhibit the typical dermoscopic findings of fissures and ridges, hairpin vessels with white halo, comedo-like openings, and milia-like cysts, all of which are helpful to distinguish SK from melanoma, melanocytic nevus, squamous cell carcinoma, basal cell carcinoma (BCC) and other skin tumors. Histopathologically, these dermoscopic characteristics correspond to papillomatous surface of the epidermis, enlarged capillaries of the dermal papillae, pseudohorn cysts in the epidermis opened to the surface of the lesion and intraepidermal cysts, respectively...
May 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28385330/a-similar-local-immune-and-oxidative-stress-phenotype-in-vitiligo-and-halo-nevus
#6
Yuqi Yang, Shuli Li, Guannan Zhu, Qian Zhang, Gang Wang, Tianwen Gao, Chunying Li, Lin Wang, Zhe Jian
BACKGROUND: Vitiligo and halo nevus are two common T-cell-mediated skin disorders. Although autoimmunity has been suggested to be involved in both diseases, the relationship between vitiligo and halo nevus is not fully understood. OBJECTIVE: The aim of the current study was to investigate whether vitiligo and halo nevus share the same immunological and oxidative stress response. METHODS: Infiltrations of T cells, and expressions of chemokine receptors (CXCR3, CCR4, CCR5) and cytotoxic markers (Granzyme B, Perforin) in the lesions of vitiligo and halo nevus were examined by immunohistochemistry...
July 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/28317531/special-considerations-in-children-with-vitiligo
#7
REVIEW
Alain Taïeb, Julien Seneschal, Juliette Mazereeuw-Hautier
Childhood vitiligo differs from adult-onset vitiligo for several features including increased incidence of the segmental variant, higher prevalence of halo nevi, and more common family history for autoimmune diseases and atopic diathesis. The major differential diagnoses are the postinflammatory hypomelanoses for nonsegmental vitiligo and nevus depigmentosus for segmental vitiligo. From a therapeutic standpoint, early awareness of the diagnosis seems to correlate with a good treatment outcome in this age group...
April 2017: Dermatologic Clinics
https://www.readbyqxmd.com/read/28141766/choroidal-nevus-a-review-of-prevalence-features-genetics-risks-and-outcomes
#8
REVIEW
Jason L Chien, Kareem Sioufi, Thamolwan Surakiatchanukul, Jerry A Shields, Carol L Shields
PURPOSE OF REVIEW: To review the prevalence, clinical features, imaging findings, cytogenetics, and risks and outcomes of choroidal nevus. RECENT FINDINGS: Choroidal nevus is a benign melanocytic tumor, often discovered incidentally on ophthalmic examination. This lesion is generally well circumscribed and pigmented. The prevalence of choroidal nevus in postequatorial region in United States adults (≥40 years old) is approximately 5%. Choroidal nevus is associated with higher lifetime unopposed estrogen and greater BMI...
May 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28135210/polypoid-spitz-nevus-with-a-halo-reaction
#9
Angel Fernandez-Flores, Marcela Saeb-Lima, José Luis Rodriguez-Peralto
Approximately, 2% of Spitz nevi are polypoid; between 3.6% and 7.4% present with a halo reaction. In tandem, these low percentages make the presence of a polypoid Spitz nevus with a halo reaction uncommon; we have not found reports of any previous cases. In the current report, we present a polypoid Spitz nevus with a halo reaction on the back of a 10-year-old male and discuss the morphologic findings. The lesion showed preserved nuclear expression of BAP1. There was no immunohistochemical expression of BRAF and ALK, while the melanocytic cells expressed p16...
February 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/27870733/cutaneous-metastatic-melanoma-resembling-a-halo-nevus-in-the-setting-of-pd-1-inhibition
#10
Nathan Tobias Harvey, Michael Millward, Kirstie Macgregor, Robert Paul Bucat, Benjamin Andrew Wood
Malignant melanoma is a common source of cutaneous metastases and can occasionally adopt a histological appearance which mimics a primary melanocytic lesion, either benign or malignant. The authors describe a case of new cutaneous deposits of metastatic melanoma in a 70-year-old woman with a prominent admixed lymphocytic infiltrate, imparting a striking resemblance to a halo nevus. The authors believe this appearance was a direct reflection of treatment with pembrolizumab, a humanized antibody against the immune checkpoint inhibitor programmed death-1...
December 2016: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/27778391/sclerotic-regressing-large-congenital-nevus
#11
Aikaterini Patsatsi, Miltiadis Kokolios, Olga Pikou, Vasilios Lambropoulos, Ioannis Efstratiou, Dimitrios Sotiriadis
Regression of congenital nevi is usually associated with loss of pigment or halo formation. In rare cases, regression is characterized by sclerosis and hair loss. We describe a rare case of a sclerotic hypopigmented large congenital melanocytic nevus in which a localized scleroderma-like reaction process of regression seemed to have started in utero and progressed throughout early childhood.
November 2016: Pediatric Dermatology
https://www.readbyqxmd.com/read/27573288/spontaneous-regression-of-a-congenital-melanocytic-nevus-by-sclerosis
#12
Eric K W Wong, Muhammad N Mahmood, Thomas G Salopek
Congenital melanocytic nevi (CMNs) naturally evolve throughout life, growing proportionately with the child, darkening, and exhibiting textural or surface changes (e.g., papillomatous, verrucous, cerebriform), hypertrichosis, and, later in life, lightening of pigmentation. We report the case of a 5-year-old child with complete resolution of a medium-sized CMN involving the distal left leg and foot via sclerosis and in the absence of any halo phenomenon. Spontaneous regression of CMN via sclerosis is rare, and it is thought that an immunologic mechanism different from the mechanism that the halo phenomenon induces mediates this regression...
November 2016: Pediatric Dermatology
https://www.readbyqxmd.com/read/27317534/blue-nevus-with-halo
#13
Edith Arzberger, Anna Niederkorn, Lorenzo Cerroni, Rainer Hofmann-Wellenhof
No abstract text is available yet for this article.
July 2016: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/27149137/meyerson-phenomenon-as-a-component-of-melanoma-in-situ
#14
Engin Sezer, Emel Özturk Durmaz, Emel Çetin, Sedef Şahin
Meyerson phenomenon (MP) is characterized by a symmetrical area of erythema and scales encircling a central lesion, which is most commonly a banal melanocytic nevus. Herein, we describe an unusual case with MP representing an eczematized response to a melanoma in situ and review the literature covering this entity. A 56-year-old man presented with a 6-month history of a pruritic, pigmented lesion on the trunk. The patient had no other significant medical history and no notable family history of similar lesions...
April 2016: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/27057061/throwing-light-onto-the-core-of-a-halo-nevus-a-new-finding
#15
Ashwini Babu, M Ramesh Bhat, Sukumar Dandeli, Neema M Ali
No abstract text is available yet for this article.
March 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/26935480/pigment-loss-in-patients-with-large-congenital-melanocytic-nevi-various-clinical-presentations-documented-in-a-large-series
#16
COMPARATIVE STUDY
Algün Polat Ekinci, Sila Kiliç, Can Baykal
BACKGROUND/OBJECTIVES: The association between vitiligo and congenital melanocytic nevi remains incompletely understood. The objective of this study was to investigate the frequency of depigmentation, including vitiligo, in patients with a large congenital melanocytic nevus (LCMN), which is a rare melanocytic tumor variant. METHODS: We retrospectively reviewed the files of 92 patients with an LCMN, including photographic documentation regarding the presence of pigment loss on the nevus mass, around the nevus, around the satellites, and elsewhere on the body...
May 2016: Pediatric Dermatology
https://www.readbyqxmd.com/read/26627472/resolution-of-vitiligo-following-excision-of-halo-congenital-melanocytic-nevus-a-rare-case-report
#17
Kai Wang, Zhi Wang, Weiqing Huang
Halo congenital melanocytic nevus (CMN) associated with vitiligo is rare, especially with regard to CMN excision. Only two reports of excision of halo CMN following repigmentation of vitiligo are found in the literature. We present a case of a girl with halo CMN and periorbital vitiligo. The halo CMN was excised and followed by spontaneous improvement of vitiligo. The result suggests excision of the inciting lesion may be a promising way to control vitiligo.
May 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/26588343/spontaneous-involution-of-congenital-melanocytic-nevus-with-halo-phenomenon
#18
Noo Ri Lee, Hee-Chul Chung, Hannah Hong, Jin Wook Lee, Sung Ku Ahn
Congenital melanocytic nevus (CMN) is a neural crest-derived hamartoma, which appear at or soon after birth. CMN has a dynamic course and may show variable changes over time, including spontaneous involution. Spontaneous involution of CMN is a rare phenomenon and is often reported in association with halo phenomenon or vitiligo. The mechanism of halo phenomenon is yet to be investigated but is suggested to be a destruction of melanocytes by immune responses of cytotoxic T cells or IgM autoantibodies. Here, the authors report an interesting case of spontaneously regressed medium-sized CMN with halo phenomenon and without vitiligo, which provides evidence that cytotoxic T cells account for the halo formation and pigmentary regression of CMN...
December 2015: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/26573093/comparison-of-childhood-vitiligo-presenting-with-or-without-associated-halo-nevi
#19
COMPARATIVE STUDY
Brandon E Cohen, Euphemia W Mu, Seth J Orlow
BACKGROUND: Previous studies have characterized differences in vitiligo associated with halo nevi, but the features of vitiligo presenting with halo nevus in children have yet to be fully described. AIMS: We sought to provide an epidemiologic and clinical comparison of cases of childhood vitiligo presenting with or without associated halo nevi. MATERIALS AND METHODS: This was a retrospective chart review of children diagnosed with vitiligo in an academic pediatric dermatology practice from January 1990 to November 2014...
January 2016: Pediatric Dermatology
https://www.readbyqxmd.com/read/26429156/morphological-features-of-melanocytic-tumors-with-depigmented-halo-review-of-the-literature-and-personal-results
#20
REVIEW
Roxana Ioana Nedelcu, Sabina Andrada Zurac, Alice Brînzea, Mirela Daniela Cioplea, Gabriela Turcu, Raluca Popescu, Cătălin Mihai Popescu, Daniela Adriana Ion
Halo (Sutton's) phenomenon has been described as a depigmented halo that is associated most commonly with acquired melanocytic nevi; but it may be associated with various types of melanocytic skin tumors, melanoma being the most concerning. Different authors have been preoccupied with elucidating morphological features of melanocytic tumors associated with a depigmented halo. We reviewed the literature and discussed the main features of melanocytic halo tumors regarding histopathological, immune microenvironment profile and dermatoscopic appearance...
2015: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
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