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https://www.readbyqxmd.com/read/27843749/mortality-markers-in-nosocomial-klebsiella-pneumoniae-bloodstream-infection
#1
Bulent Durdu, Ismail Necati Hakyemez, Sibel Bolukcu, Gulay Okay, Bilge Gultepe, Turan Aslan
PURPOSE: Klebsiella pneumoniae is the most common endogen agent for nosocomial infections. In this study, mortality markers were investigated in patients with nosocomial K. pneumoniae blood stream infection (NKp BSI). METHODS: The characteristics of patients >16 years who had NKp BSI diagnosis by daily active surveillance between January 2012 and January 2016 were retrospectively evaluated. Patients who died until 28th day of the clinical follow up and those who survived until this time were statistically compared in terms of various risk factors...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27832392/epidemiology-and-mortality-of-candidemia-both-related-and-unrelated-to-the-central-venous-catheter-a-retrospective-cohort-study
#2
S Arias, O Denis, I Montesinos, S Cherifi, V Y Miendje Deyi, F Zech
Our objective was to compare mortality, epidemiology, and morbidity in hospitalized patients with candidemia which was both related and unrelated to the central venous catheter (CVC). This was a monocentric, retrospective cohort study of candidemia. The sample consisted of 103 patients with laboratory-confirmed nosocomial candidemia hospitalized between 2006 and 2013 in a tertiary care public hospital. We included 65 (63.1 %) patients (24 in the CVC-positive group, 41 in the CVC-negative group). Demographic data and risk factors were recorded using a structured case report form...
November 10, 2016: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/27495046/risk-factors-for-mortality-in-patients-with-stenotrophomonas-maltophilia-bacteremia
#3
Yong Duk Jeon, Woo Yong Jeong, Moo Hyun Kim, In Young Jung, Mi Young Ahn, Hea Won Ann, Jin Young Ahn, Sang Hoon Han, Jun Yong Choi, Young Goo Song, June Myung Kim, Nam Su Ku
Stenotrophomonas maltophilia is a nosocomial pathogen associated with high morbidity and mortality, particularly in immunocompromised or critically ill patients. In this study, we investigated the risk factors for mortality in patients with S. maltophilia bacteremia.Retrospectively, medical records from all patients with S. maltophilia bacteremia between December 2005 and 2014 at Severance Hospital, a 2000-bed tertiary care hospital in Seoul, Korea, were reviewed. Analysis was performed to identify factors associated with 28-day mortality...
August 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27437303/malposition-of-subclavian-venous-catheter-leading-to-chest-complications
#4
Madhur Kumar, Amarjit Singh, Kuldeep Singh Sidhu, Avleen Kaur
Although Central Venous Catheter (CVC) placement is a relatively simple procedure but its insertion and maintenance are associated with significant risks. Malposition (defined as any CVC tip position outside the superior vena cava) may be associated with catheter insertion and may require immediate intervention. It may result in complications like haemothorax, pleural effusions, pneumothorax, sepsis, thrombosis and cardiac tamponade. This case report presents timely detection of the complication after placement of CVC...
May 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27410189/skin-antisepsis-for-reducing-central-venous-catheter-related-infections
#5
REVIEW
Nai Ming Lai, Nai An Lai, Elizabeth O'Riordan, Nathorn Chaiyakunapruk, Jacqueline E Taylor, Kenneth Tan
BACKGROUND: The central venous catheter (CVC) is a device used for many functions, including monitoring haemodynamic indicators and administering intravenous medications, fluids, blood products and parenteral nutrition. However, as a foreign object, it is susceptible to colonisation by micro-organisms, which may lead to catheter-related blood stream infection (BSI) and in turn, increased mortality, morbidities and health care costs. OBJECTIVES: To assess the effects of skin antisepsis as part of CVC care for reducing catheter-related BSIs, catheter colonisation, and patient mortality and morbidities...
July 13, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27401690/nosocomial-candidemia-in-patients-admitted-to-medicine-wards-compared-to-other-wards-a-multicentre-study
#6
Roberto Luzzati, Maria Merelli, Filippo Ansaldi, Chiara Rosin, Annamaria Azzini, Silvia Cavinato, Pierluigi Brugnaro, Claudio Vedovelli, Annamaria Cattelan, Busetti Marina, Giuseppe Gatti, Ercole Concia, Matteo Bassetti
PURPOSE: Risk factors for nosocomial candidemia, severity of sepsis, treatment, and outcome were compared between patients admitted to medicine wards and those to surgical and intensive care units (ICUs). METHODS: Data were retrospectively collected from patients belonging to six referral hospitals in Italy between January 2011 and December 2013. Risk factors for 30-day mortality were evaluated in the whole patient population. RESULTS: A total of 686 patients (mean age 70 ± 15 years) with candidemia were included...
July 11, 2016: Infection
https://www.readbyqxmd.com/read/27397443/comparison-between-noninvasive-measurement-of-central-venous-pressure-using-near-infrared-spectroscopy-with-an-invasive-central-venous-pressure-monitoring-in-cardiac-surgical-intensive-care-unit
#7
N Sathish, Naveen G Singh, P S Nagaraja, B M Sarala, C G Prabhushankar, Manasa Dhananjaya, N Manjunatha
INTRODUCTION: Central venous pressure (CVP) measurement is essential in the management of certain clinical situations, including cardiac failure, volume overload and sepsis. CVP measurement requires catheterization of the central vein which is invasive and may lead to complications. The aim of this study was to evaluate the accuracy of measurement of CVP using a new noninvasive method based on near infrared spectroscopy (NIRS) in a group of cardiac surgical Intensive Care Unit (ICU) patients...
July 2016: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/27112774/distance-of-the-internal-central-venous-catheter-tip-from-the-right-atrium-is-positively-correlated-with-central-venous-thrombosis
#8
David H Ballard, Navdeep S Samra, Karen Mathiesen Gifford, Robert Roller, Bruce M Wolfe, John T Owings
Central venous catheters (CVCs) are associated with occlusive, infectious, and thrombotic complications. The aim of this study was to determine if internal CVC tip position was correlated with subsequent complications. This was an institutional review board approved single-center retrospective review of 169 consecutive patients who underwent placement of 203 semipermanent CVCs. Using post-placement chest X-rays, a de novo scale of internal catheter tip position was developed. Major complications were recorded...
June 2016: Emergency Radiology
https://www.readbyqxmd.com/read/27007217/antimicrobial-dressings-for-the-prevention-of-catheter-related-infections-in-newborn-infants-with-central-venous-catheters
#9
REVIEW
Nai Ming Lai, Jacqueline E Taylor, Kenneth Tan, Yao Mun Choo, Azanna Ahmad Kamar, Nor Asiah Muhamad
BACKGROUND: Central venous catheters (CVCs) provide secured venous access in neonates. Antimicrobial dressings applied over the CVC sites have been proposed to reduce catheter-related blood stream infection (CRBSI) by decreasing colonisation. However, there may be concerns on the local and systemic adverse effects of these dressings in neonates. OBJECTIVES: We assessed the effectiveness and safety of antimicrobial (antiseptic or antibiotic) dressings in reducing CVC-related infections in newborn infants...
March 23, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26982376/catheter-impregnation-coating-or-bonding-for-reducing-central-venous-catheter-related-infections-in-adults
#10
REVIEW
Nai Ming Lai, Nathorn Chaiyakunapruk, Nai An Lai, Elizabeth O'Riordan, Wilson Shu Cheng Pau, Sanjay Saint
BACKGROUND: The central venous catheter (CVC) is essential in managing acutely ill patients in hospitals. Bloodstream infection is a major complication in patients with a CVC. Several infection control measures have been developed to reduce bloodstream infections, one of which is impregnation of CVCs with various forms of antimicrobials (either with an antiseptic or with antibiotics). This review was originally published in June 2013 and updated in 2016. OBJECTIVES: Our main objective was to assess the effectiveness of antimicrobial impregnation, coating or bonding on CVCs in reducing clinically-diagnosed sepsis, catheter-related blood stream infection (CRBSI), all-cause mortality, catheter colonization and other catheter-related infections in adult participants who required central venous catheterization, along with their safety and cost effectiveness where data were available...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26557553/analysis-of-vascular-access-in-haemodialysis-patients-single-center-experience
#11
R Hemachandar
BACKGROUND: Vascular access is the key in successful management of chronic haemodialysis (HD) patients. Though native arteriovenous fistula (AVF) is considered the access of choice, many patients in our country initiate haemodialysis through central venous catheter (CVC). There is paucity of data on vascular access in haemodialysis patients from southern India. AIM: Aim of the present study was to review our experience of vascular access in Haemodialysis patients (both central venous catheters and arteriovenous fistula) and to assess its success rate and common complications...
October 2015: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26489832/development-of-quality-indicators-and-data-assessment-strategies-for-the-prevention-of-central-venous-catheter-related-bloodstream-infections-crbsi
#12
Anke Bramesfeld, Stephanie Wrede, Klaus Richter, Mareike Steen, Björn Broge, Jürgen Pauletzki, Joachim Szecsenyi
BACKGROUND: The number of catheter related bloodstream infections (CRBSI) could be reduced and the outcome improved if specific standards in the quality of care were maintained. Therefore, the development of quality assurance (QA) procedures was commissioned to be included in the national mandatory QA programme in Germany. METHODS: Indicators representing quality deficiencies and potential for improvement of quality in relation to prevention and management of central venous catheters (CVC) were developed by (1) evidence-based literature searches and the compiling of an indicator register; (2) a multi-professional expert panel including patient representatives who selected indicators from this register by using a modified RAND/UCLA Appropriateness Method; (3) defining methods for data assessment, risk adjustment and feedback of indicator results to service providers; and (4) consulting all relevant medical societies and other stakeholders with regard to the QA procedures that had been developed...
2015: BMC Infectious Diseases
https://www.readbyqxmd.com/read/26480255/-getting-to-zero-infections-in-hemodialysis
#13
Gianluca Leonardi, Giuseppe Finotto, Marinella Talaia, Angelo Nappo, Caterina Dolla, Maria Cristina Di Vico, Davide Diena, Antonio Linsalata, Cesare Guarena, Silvana Barbaro, Luigi Biancone
INTRODUCTION: We describe two measures adopted in hemodialysis outpatient population in order to reduce Central Venous Catheter (CVC) related infections. The first is a nurse staff training in the field project and the second deals with the employment of chlorhexidine-impregnated dressing devices. These actions were performed after high infection rates were observed through a dedicated register. MATERIALS AND METHODS: In the limited assistance dialysis center, direct observation (12/2012-02/2013) quantified the gap between the observed and expected health care behaviour...
September 2015: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/26439212/osteomyelitis-in-adult-patients-on-long-term-parenteral-nutrition-2745-patient-years-of-experience-in-a-national-referral-centre
#14
P Allan, P Stevens, P Chadwick, A Teubner, A Abraham, G Carlson, S Lal
BACKGROUND & AIMS: Osteomyelitis (OM) is a rare complication of catheter related sepsis after central venous catheter (CVC) use. The prevalence, characteristics and diagnosis of OM in patients with intestinal failure (IF) receiving long term parenteral nutrition (PN) through CVCs have not previously been described. METHODS: This was a retrospective study from a prospectively maintained database of patients referred to a National IF centre. Age, IF aetiology, past medical history, time on PN, OM site and organism(s) cultured were recorded...
October 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/26265898/kluyvera-ascorbata-infections-in-children-a-case-series
#15
Eda Karadağ Öncel, Yasemin Özsürekci, Yakut Akyön, Deniz Gür, Ali Bülent Cengiz, Ateş Kara
Kluyvera is a relatively newly described member of the Enterobacteriaceae family that rarely causes infections in humans. In the pediatric population, it is described in association with clinically significant infections ranging from urinary tract infections to sepsis with multiorgan failure. Our aim is to determine the clinical significance of K. ascorbata infections in the pediatric population at our institution. We retrospectively analyzed clinical microbiology data as from 2006 and identified four clinically significant isolates in this period...
June 2015: Türk Pediatri Arşivi
https://www.readbyqxmd.com/read/26235268/-recombinant-tissue-plasminogen-activator-for-the-management-of-intracardiac-thrombi-in-newborns
#16
Patricia Álvarez Z, Patricia Verdugo L, Luis Carvajal K, Germán Múhlhausen M, Patricia Ríos A, Diego Rodríguez V
INTRODUCTION: The incidence of cardiac thrombi in newborns has increased with the use of central venous catheters. Thrombolysis with recombinant tissue plasminogen activator (rTPA) has been used as an alternative to heparin in life threatening giant thrombus and embolization. The aim of this study is to describe the response and complications related to the use of rTPA in the management of life- threatening cardiac thrombi in newborns. PATIENTS AND METHOD: The medical records of 8 newborn were reviewed in a retrospective study, of whom 7 were preterm with cardiac thrombi, and rTPA was used in all of them...
May 2015: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/26175012/approach-to-non-neutropenic-fever-in-pediatric-oncology-patients-a-single-institution-study
#17
Bilal Abou Ali, Nader Hirmas, Hani Tamim, Zeina Merabi, Rima Hanna-Wakim, Samar Muwakkit, Miguel Abboud, Hassan El Solh, Raya Saab
BACKGROUND: Pediatric oncology patients with fever, even when not neutropenic, are known to be at an increased risk of bloodstream infections. However, there are no standard guidelines for management of fever in non-neutropenic patients, resulting in variability in practice across institutions. PROCEDURE: We retrospectively analyzed the clinical characteristics, management, and outcome of all febrile non-neutropenic episodes in pediatric oncology patients at a single institution over the two-year period 2011-2012, to identify predictors of bloodstream infections...
December 2015: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/26170772/antibiotics-before-removal-of-percutaneously-inserted-central-venous-catheters-reduces-clinical-sepsis-in-premature-infants
#18
Gail E Reynolds, Sarah B Tierney, Jonathan M Klein
OBJECTIVES: Evaluate the incidence of postcatheter removal clinical sepsis when antibiotics were infused prior to the removal of percutaneously inserted central venous catheters (PICCs). METHODS: A retrospective chart review of premature neonates (n = 196) weighing ≤1250 g at birth with 218 PICC line removals in the presence or absence of antibiotics at a tertiary level neonatal intensive care unit (NICU) between January 1, 2010, and May 31, 2012. Charts were reviewed looking for the presence of clinical sepsis defined as a sepsis workup including white blood cell count, differential, C-reactive protein, blood and/or cerebral spinal fluid (CSF), and urine cultures along with at least 48 hours of antibiotic therapy given within 72 hours after removal of a PICC line...
May 2015: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://www.readbyqxmd.com/read/26111103/vte-incidence-and-risk-factors-in-patients-with-severe-sepsis-and-septic-shock
#19
David Kaplan, T Charles Casper, C Gregory Elliott, Shaohua Men, Robert C Pendleton, Larry W Kraiss, Andrew S Weyrich, Colin K Grissom, Guy A Zimmerman, Matthew T Rondina
BACKGROUND: Prospective studies on the incidence of VTE during severe sepsis and septic shock remain absent, hindering efficacy assessments regarding VTE prevention strategies in sepsis. METHODS: We prospectively studied 113 consecutively enrolled patients in the ICU with severe sepsis and septic shock at three hospitals. All patients provided informed consent. VTE thromboprophylaxis was recorded for all patients. Patients underwent ultrasonography and were followed for VTE prior to ICU discharge...
November 2015: Chest
https://www.readbyqxmd.com/read/26110291/medical-care-related-laboratory-confirmed-bloodstream-infections-in-paediatrics
#20
Silvia Virano, Carlo Scolfaro, Silvia Garazzino, Carlo De Intinis, Valeria Ghisetti, Irene Raffaldi, Carmelina Calitri, Pier Angelo Tovo
The aim of this survey was to describe the incidence, epidemiology, microbiology, risk factors and outcome of medical care related laboratory-confirmed bloodstream infections (LCBIs) observed during a twelve-month prospective study in a Paediatric Teaching Hospital in Turin, Italy. Inclusion criteria were clinical signs of sepsis and positivity of one or more of the following tests: blood culture, polymerase chain reaction for bacterial and fungal DNA on blood, and culture on intravascular device tips. In all, 140 episodes of sepsis were documented in 131 children: 37 (26...
June 2015: Le Infezioni in Medicina
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