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https://www.readbyqxmd.com/read/29346162/specificity-of-live-high-train-low-altitude-training-on-exercise-performance
#1
Jacob Bejder, Nikolai Baastrup Nordsborg
The novel hypothesis that "Live High-Train Low" (LHTL) does not improve sport-specific exercise performance (e.g., time trial) is discussed. Indeed, many studies demonstrate improved performance after LHTL but unfortunately control groups are often lacking, leaving open the possibility of training camp effects. Importantly, when control groups, blinding procedures and strict scientific evaluation criteria are applied, LHTL has no detectable effect on performance.
January 15, 2018: Exercise and Sport Sciences Reviews
https://www.readbyqxmd.com/read/29339423/immune-protection-against-lethal-fungal-bacterial-intra-abdominal-infections
#2
Elizabeth A Lilly, Melanie Ikeh, Evelyn E Nash, Paul L Fidel, Mairi C Noverr
Polymicrobial intra-abdominal infections (IAIs) are clinically prevalent and cause significant morbidity and mortality, especially those involving fungi. Our laboratory developed a mouse model of IAI and demonstrated that intraperitoneal inoculation with Candida albicans or other virulent non-albicans Candida (NAC) species plus Staphylococcus aureus resulted in 70 to 80% mortality in 48 to 72 h due to robust local and systemic inflammation (sepsis). Surprisingly, inoculation with Candida dubliniensis or Candida glabrata with S...
January 16, 2018: MBio
https://www.readbyqxmd.com/read/29330835/international-guidelines-for-groin-hernia-management
#3
(no author information available yet)
INTRODUCTION: Worldwide, more than 20 million patients undergo groin hernia repair annually. The many different approaches, treatment indications and a significant array of techniques for groin hernia repair warrant guidelines to standardize care, minimize complications, and improve results. The main goal of these guidelines is to improve patient outcomes, specifically to decrease recurrence rates and reduce chronic pain, the most frequent problems following groin hernia repair. They have been endorsed by all five continental hernia societies, the International Endo Hernia Society and the European Association for Endoscopic Surgery...
January 12, 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/29329528/transmission-of-measles-among-healthcare-workers-in-hospital-w-xinjiang-autonomous-region-china-2016
#4
Haimei Jia, Chao Ma, Mengting Lu, Jianping Fu, Lance E Rodewald, Qiru Su, Huaqin Wang, Lixin Hao
BACKGROUND: As China approaches the elimination of measles, outbreaks of measles continue to occur. Healthcare workers (HCWs) are known to be at high risk of infection and transmission of measles virus. A measles outbreak occurred in a hospital in Xinjiang Uighur Autonomous Region of the People's Republic of China. We report an investigation of this outbreak and its implications for measles elimination and outbreak preparedness. METHODS: We conducted a retrospective search for measles cases using hospital records...
January 12, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29319511/study-of-patterns-and-markers-of-human-immune-deficiency-virus-1-hiv-1-progression-and-unemployment-rate-among-patients-from-alexandria-egypt
#5
Faika M Ghoneim, May M Raouf, Noha S Elshaer, Sarah M Abdelhamid, Reem A Noor Eldeen
Middle East and North Africa (MENA) new HIV cases show the highest increase among all regions in the world. Even though Egypt has a low prevalence among the general population (< 0.02%), a national HIV epidemic occurs in certain population risk groups. The current study was conducted to asses clinical and immunological disease progression; following up viral load (VL) and detecting delta-32 CCR5 genotype polymorphism in selected cases, determining unemployment rate and identify predictors of employment for HIV-cases...
December 4, 2017: Polish Journal of Microbiology
https://www.readbyqxmd.com/read/29304139/early-neonatal-mortality-and-neurological-outcomes-of-neonatal-resuscitation-in-a-resource-limited-setting-on-the-thailand-myanmar-border-a-descriptive-study
#6
Sophie Janet, Verena I Carrara, Julie A Simpson, Nant War War Thin, Wah Wah Say, Naw Ta Mlar Paw, Kesinee Chotivanich, Claudia Turner, Jane Crawley, Rose McGready
BACKGROUND: Of the 4 million neonatal deaths worldwide yearly, 98% occur in low and middle-income countries. Effective resuscitation reduces mortality and morbidity but long-term outcomes in resource-limited settings are poorly described. This study reports on newborn neurological outcomes following resuscitation at birth in a resource-limited setting where intensive newborn care including intubation is unavailable. METHODS: Retrospective analysis of births records from 2008 to 2015 at Shoklo Malaria Research Unit (SMRU) on the Thailand-Myanmar border...
2018: PloS One
https://www.readbyqxmd.com/read/29298703/cultural-adaptation-of-a-peer-led-lifestyle-intervention-program-for-diabetes-prevention-in-india-the-kerala-diabetes-prevention-program-k-dpp
#7
Elezebeth Mathews, Emma Thomas, Pilvikki Absetz, Fabrizio D'Esposito, Zahra Aziz, Sajitha Balachandran, Meena Daivadanam, Kavumpurathu Raman Thankappan, Brian Oldenburg
BACKGROUND: Type 2 diabetes mellitus (T2DM) is now one of the leading causes of disease-related deaths globally. India has the world's second largest number of individuals living with diabetes. Lifestyle change has been proven to be an effective means by which to reduce risk of T2DM and a number of "real world" diabetes prevention trials have been undertaken in high income countries. However, systematic efforts to adapt such interventions for T2DM prevention in low- and middle-income countries have been very limited to date...
January 4, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29284702/high-background-congenital-microcephaly-in-rural-guatemala-implications-for-neonatal-congenital-zika-virus-infection-screening
#8
Anne-Marie Rick, Gretchen Domek, Maureen Cunningham, Daniel Olson, Molly M Lamb, Andrea Jimenez-Zambrano, Gretchen Heinrichs, Stephen Berman, Edwin J Asturias
BACKGROUND: Congenital microcephaly is the result of a disturbance in early brain development and can have multiple etiologies. Establishing background prevalence of microcephaly in Zika virus (ZIKV)-affected areas is important for improving identification of ZIKV-affected newborns. However, to date, there is limited consistent guidance for the accurate identification of microcephaly in infants of unknown gestational age, a common concern in low- and middle-income countries. METHODS: Occipital frontal head circumference (OFC) obtained from infants (0-13 days) of unknown gestational age at enrollment in a pregnancy registry in rural Guatemala from August 2014 to March 2016 were retrospectively reviewed...
December 28, 2017: Global Health, Science and Practice
https://www.readbyqxmd.com/read/29284075/atraumatic-restorative-treatment-versus-conventional-restorative-treatment-for-managing-dental-caries
#9
REVIEW
Mojtaba Dorri, Maria José Martinez-Zapata, Tanya Walsh, Valeria Cc Marinho, Aubrey Sheiham Deceased, Carlos Zaror
BACKGROUND: Dental caries is a sugar-dependent disease that damages tooth structure and, due to loss of mineral components, may eventually lead to cavitation. Dental caries is the most prevalent disease worldwide and is considered the most important burden of oral health. Conventional treatment methods (drill and fill) involve the use of rotary burs under local anaesthesia. The need for an electricity supply, expensive handpieces and highly trained dental health personnel may limit access to dental treatment, especially in underdeveloped regions...
December 28, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29281636/healthcare-provider-perspectives-on-managing-sexually-transmitted-infections-in-hiv-care-settings-in-kenya-a-qualitative-thematic-analysis
#10
Kipruto Chesang, Sureyya Hornston, Odylia Muhenje, Teresa Saliku, Joy Mirjahangir, Amanda Viitanen, Helgar Musyoki, Christine Awuor, George Githuka, Naomi Bock
BACKGROUND: The burden of sexually transmitted infections (STIs) has been increasing in Kenya, as is the case elsewhere in sub-Saharan Africa, while measures for control and prevention are weak. The objectives of this study were to (1) describe healthcare provider (HCP) knowledge and practices, (2) explore HCP attitudes and beliefs, (3) identify structural and environmental factors affecting STI management, and (4) seek recommendations to improve the STI program in Kenya. METHODS AND FINDINGS: Using individual in-depth interviews (IDIs), data were obtained from 87 HCPs working in 21 high-volume comprehensive HIV care centers (CCCs) in 7 of Kenya's 8 regions...
December 2017: PLoS Medicine
https://www.readbyqxmd.com/read/29278455/genetic-diagnosis-of-down-syndrome-in-an-underserved-community
#11
Andrew K Sobering, Joshua B Stevens, Janice L Smith, Beverly Nelson, Tyhiesia Donald, Sarah H Elsea
It is a matter of course that in high-income countries, infants born with features suggestive of Down syndrome (DS) are offered genetic testing for confirmation of a clinical diagnosis. Benefits of a definitive diagnosis include an end to the diagnostic odyssey, informed prognosis, opportunities for caregiver support, inclusion to social support networks, and more meaningful genetic counseling. The healthcare experience for families of children born with DS in low- and middle-income nations is in stark contrast with such a level of care...
December 26, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29258462/determinants-of-unmet-need-for-family-planning-in-rural-burkina-faso-a-multilevel-logistic-regression-analysis
#12
Joseph K Wulifan, Albrecht Jahn, Hervé Hien, Patrick Christian Ilboudo, Nicolas Meda, Paul Jacob Robyn, T Saidou Hamadou, Ousmane Haidara, Manuela De Allegri
BACKGROUND: Unmet need for family planning has implications for women and their families, such as unsafe abortion, physical abuse, and poor maternal health. Contraceptive knowledge has increased across low-income settings, yet unmet need remains high with little information on the factors explaining it. This study assessed factors associated with unmet need among pregnant women in rural Burkina Faso. METHOD: We collected data on pregnant women through a population-based survey conducted in 24 rural districts between October 2013 and March 2014...
December 19, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29247273/live-high-train-low-guided-by-daily-heart-rate-variability-in-elite-nordic-skiers
#13
Laurent Schmitt, Sarah J Willis, Anthony Fardel, Nicolas Coulmy, Gregoire P Millet
PURPOSE: To analyze if live high-train low (LHTL) effectiveness is improved when daily training is guided by heart rate variability (HRV). METHODS: Twenty-four elite Nordic skiers took part in a 15-day LHTL study and were randomized into a HRV-guided training hypoxic group (H-HRV, n = 9, sleeping in normobaric hypoxia, FiO2 = 15.0%) and two predefined training groups sleeping either in hypoxia (H, n = 9, FiO2 = 15.0%) or normoxia (N, n = 6). HRV and training loads (TL) were recorded daily...
December 15, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29247024/is-live-high-train-low-altitude-training-relevant-for-elite-athletes-flawed-analysis-from-inaccurate-data
#14
EDITORIAL
Gregoire P Millet, Robert F Chapman, Olivier Girard, Franck Brocherie
No abstract text is available yet for this article.
December 15, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/29235172/scaling-up-child-development-centres-in-bangladesh
#15
N Z Khan, R Sultana, F Ahmed, A B Shilpi, N Sultana, G L Darmstadt
BACKGROUND: Child Development Centres (CDCs) have been established within government medical college tertiary hospitals across Bangladesh. Services entail a parent-professional partnership in a child and family friendly environment with a focus on assessment, diagnosis, and management of a range of neurodevelopmental disorders in children and adolescents 0-16 years of age. Services are provided by a multidisciplinary team of professionals (child health physician, child psychologist, and developmental therapist) who emphasize quality of services over the numbers of children seen...
January 2018: Child: Care, Health and Development
https://www.readbyqxmd.com/read/29232524/growing-the-ibclc-workforce-a-florida-needs-assessment
#16
Aimee R Eden, Erica H Anstey, Deidre Orriola
BACKGROUND: Florida has fewer International Board Certified Lactation Consultants (IBCLCs) per 1,000 live births than the national average. An important strategy to support breastfeeding entails creating opportunities to prepare and train IBCLCs from underrepresented groups. However, it can be difficult for individuals to access lactation education and gain clinical experience necessary to become an IBCLC. Research aim: The Building a Better Breastfeeding Network project was a needs assessment designed to assess the interest in an IBCLC training program in Florida and perceived barriers and facilitators to completing such a program...
November 1, 2017: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/29219877/effectiveness-of-robotic-assisted-rehabilitation-for-mobility-and-functional-ability-in-adult-stroke-patients-a-systematic-review
#17
Kenneth Lo, Matthew Stephenson, Craig Lockwood
BACKGROUND: Stroke is a leading cause of long-term disability, and rehabilitation, involving repetitive, high intensity, task-specific exercises, is the pathway to restoring motor skills. Robotic assistive devices are increasingly being used and it is hoped that with robotic devices, rehabilitation progress can be achieved for patients. OBJECTIVES: To examine the effectiveness of robotic devices in the rehabilitation of stroke patients for upper limb mobility, lower limb mobility, and activities of daily living...
December 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29218847/potential-exposure-to-australian-bat-lyssavirus-is-unlikely-to-prevent-future-bat-handling-among-adults-in-south-east-queensland
#18
M K Young, S Banu, B J McCall, S Vlack, H Carroll, S Bennett, R Davison, D Francis
Despite ongoing public health messages about the risks associated with bat contact, the number of potential exposures to Australian bat lyssavirus (ABLV) due to intentional handling by members of the general public in Queensland has remained high. We sought to better understand the reasons for intentional handling among these members of the public who reported their potential exposure to inform future public health messages. We interviewed adults who resided in a defined geographic area in South East Queensland and notified potential exposure to ABLV due to intentional handling of bats by telephone between 1 January 2012 and 31 December 2013...
December 8, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/29212509/incremental-cost-and-cost-effectiveness-of-low-dose-high-frequency-training-in-basic-emergency-obstetric-and-newborn-care-as-compared-to-status-quo-part-of-a-cluster-randomized-training-intervention-evaluation-in-ghana
#19
Michelle Willcox, Heather Harrison, Amos Asiedu, Allyson Nelson, Patricia Gomez, Amnesty LeFevre
BACKGROUND: Low-dose, high-frequency (LDHF) training is a new approach best practices to improve clinical knowledge, build and retain competency, and transfer skills into practice after training. LDHF training in Ghana is an opportunity to build health workforce capacity in critical areas of maternal and newborn health and translate improved capacity into better health outcomes. METHODS: This study examined the costs of an LDHF training approach for basic emergency obstetric and newborn care and calculates the incremental cost-effectiveness of the LDHF training program for health outcomes of newborn survival, compared to the status quo alternative of no training...
December 6, 2017: Globalization and Health
https://www.readbyqxmd.com/read/29202731/economic-evaluation-of-emergency-obstetric-care-training-a-systematic-review
#20
Aduragbemi Banke-Thomas, Megan Wilson-Jones, Barbara Madaj, Nynke van den Broek
BACKGROUND: Training healthcare providers in Emergency Obstetric Care (EmOC) has been shown to be effective in improving their capacity to provide this critical care package for mothers and babies. However, little is known about the costs and cost-effectiveness of such training. Understanding costs and cost-effectiveness is essential in guaranteeing value-for-money in healthcare spending. This study systematically reviewed the available literature on cost and cost-effectiveness of EmOC trainings...
December 4, 2017: BMC Pregnancy and Childbirth
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