keyword
MENU ▼
Read by QxMD icon Read
search

Infection rate mortality

keyword
https://www.readbyqxmd.com/read/29470836/role-of-vancomycin-minimum-inhibitory-concentrations-by-modified-population-analysis-profile-method-and-clinical-outcomes-in-high-inoculum-methicillin-resistant-staphylococcus-aureus-infections
#1
Trang D Trinh, Evan J Zasowski, Kimberly C Claeys, Anthony M Casapao, Matthew Compton, Abdalhamid Lagnf, Shravya D Kidambi, Donald P Levine, Michael J Rybak
INTRODUCTION: Vancomycin remains the standard of care for invasive methicillin-resistant Staphylococcus aureus (MRSA) infections. Treatment failures from heteroresistant vancomycin-intermediate subpopulations (hVISA) are challenging to detect. Minimum inhibitory concentrations (MIC) identified by modified population analysis profile (PAP) is an alternative testing method. The aim of this study was to evaluate the role of PAP MIC on vancomycin failures in two high inoculum infections: MRSA infective endocarditis and pneumonia...
February 22, 2018: Infectious Diseases and Therapy
https://www.readbyqxmd.com/read/29470532/psychosocial-health-and-suicidal-ideation-among-people-living-with-hiv-aids-a-cross-sectional-study-in-nanjing-china
#2
Wei Wang, Chenchang Xiao, Xing Yao, Yinmei Yang, Hong Yan, Shiyue Li
BACKGROUND: Suicide is a serious cause of mortality worldwide and is considered as a psychiatric emergency. People living with HIV/AIDS (PLWHA) have higher rates of suicidal behavior than the general population. This study assessed the prevalence and verified the syndemic effect of psychosocial health conditions on suicidal ideation among PLWHA in China. METHODS: An institutional-based cross-sectional study was conducted from July to August 2016 in Nanjing, China, using a self-report questionnaire...
2018: PloS One
https://www.readbyqxmd.com/read/29470162/pulmonary-mucormycosis-radiologic-features-at-presentation-and-over-time
#3
Mark M Hammer, Rachna Madan, Hiroto Hatabu
OBJECTIVE: Pulmonary mucormycosis is an aggressive opportunistic fungal infection. We set out to evaluate the CT and MRI features of pulmonary mucormycosis. MATERIALS AND METHODS: Through a search of the electronic medical record from 2007 to 2017, we identified 30 patients with definite or probable mucormycosis. Two radiologists reviewed the initial chest CT examinations for the presence of features including the "reverse halo" sign, large ground-glass halo, and peripheral lesion distribution...
February 22, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29469924/t-cell-depleted-haploidentical-stem-cell-transplantation-results-improve-with-time-in-adults-with-acute-leukemia-a-study-from-the-acute-leukemia-working-party-of-the-european-society-of-blood-and-marrow-transplantation-ebmt
#4
Simona Sestili, Myriam Labopin, Annalisa Ruggeri, Andrea Velardi, Fabio Ciceri, Johan Maertens, Lothar Kanz, Franco Aversa, Philippe Lewalle, Donald Bunjes, Mohamad Mohty, Arnon Nagler
BACKGROUND: T-cell-depleted, haploidentical transplantations (haplos) are commonly offered to patients who have high-risk, acute leukemia in the absence of a human leukocyte antigen (HLA) full-matched donor. METHODS: To determine the effect of transplantation period, the authors divided 308 adults with de novo, acute leukemia who underwent T-cell-depleted haplo from 2005 to 2015 into 2 groups, according the year in which they underwent transplantation (2005-2011 [n = 191] and 2012-2015 [n = 117])...
February 22, 2018: Cancer
https://www.readbyqxmd.com/read/29469467/-study-on-oncomelania-hupensis-snails-infected-with-schistosoma-japonicum-miracidia-under-different-conditions-in-snail-existent-non-endemic-areas-of-schistosomiasis-in-nantong-city
#5
Ding Gui-Sheng, Xiong Chun-Rong, Cao Cai-Qun, Hang De-Rong, Miao Ping, Chen Ya-Fei, Sun Bo-Chao, Huang Yi-Xin
OBJECTIVE: To understand the forming cause of the Oncomelania hupensis snail-existent non-endemic areas of schistosomiasis (SENEAS), and to verify the conclusion of previous studies, so as to provide the evidence for schistosomiasis monitoring in such areas in Nantong City, Jiangsu Province. METHODS: The controlled field tests were carried out to observe the O. hupensis snails artificially infected by schistosome miracidia in SENEAS. The influence of the soil from SENEAS and the endemic areas on O...
December 18, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29468592/experimental-protocol-for-cecal-ligation-and-puncture-model-of-polymicrobial-sepsis-and-assessment-of-vascular-functions-in-mice
#6
Santosh Kumar Mishra, Soumen Choudhury
Sepsis is the systemic inflammatory response syndrome that occurs during infection and is exacerbated by the inappropriate immune response encountered by the affected individual. Despite extensive research, sepsis in humans is one of the biggest challenges for clinicians. The high mortality rate in sepsis is primarily due to hypoperfusion-induced multiorgan dysfunctions , resulting from a marked decrease in peripheral resistance. Vascular dysfunctions are further aggravated by sepsis-induced impairment in myocardial contractility...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29468090/the-role-of-bmi-in-hip-fracture-surgery
#7
Sheriff D Akinleye, Garret Garofolo, Maya Deza Culbertson, Peter Homel, Orry Erez
Introduction: Obesity is an oft-cited cause of surgical morbidity and many institutions require extensive supplementary screening for obese patients prior to surgical intervention. However, in the elderly patients, obesity has been described as a protective factor. This article set out to examine the effect of body mass index (BMI) on outcomes and morbidity after hip fracture surgery. Methods: The National Surgical Quality Improvement Program database was queried for all patients undergoing 1 of 4 surgical procedures to manage hip fracture between 2008 and 2012...
2018: Geriatric Orthopaedic Surgery & Rehabilitation
https://www.readbyqxmd.com/read/29467743/genotypic-and-phenotypic-diversity-of-cryptococcus-gattii-vgii-clinical-isolates-and-its-impact-on-virulence
#8
Vanessa A Barcellos, Liline M S Martins, Alide C L Fontes, Julia C V Reuwsaat, Eamim D Squizani, Glauber R de Sousa Araújo, Susana Frases, Charley C Staats, Augusto Schrank, Livia Kmetzsch, Marilene H Vainstein
The Cryptococcus gattii species complex harbors the main etiological agents of cryptococcosis in immunocompetent patients. C. gattii molecular type VGII predominates in the north and northeastern regions of Brazil, leading to high morbidity and mortality rates. C. gattii VGII isolates have a strong clinical relevance and phenotypic variations. These phenotypic variations among C. gattii species complex isolates suggest that some strains are more virulent than others, but little information is available related to the pathogenic properties of those strains...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29467474/an-in-vitro-proof-of-principle-study-of-sonobactericide
#9
Kirby R Lattwein, Himanshu Shekhar, Willem J B van Wamel, Tammy Gonzalez, Andrew B Herr, Christy K Holland, Klazina Kooiman
Infective endocarditis (IE) is associated with high morbidity and mortality rates. The predominant bacteria causing IE is Staphylococcus aureus (S. aureus), which can bind to existing thrombi on heart valves and generate vegetations (biofilms). In this in vitro flow study, we evaluated sonobactericide as a novel strategy to treat IE, using ultrasound and an ultrasound contrast agent with or without other therapeutics. We developed a model of IE biofilm using human whole-blood clots infected with patient-derived S...
February 21, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29467131/hiv-aids-mortality-attributable-to-alcohol-use-in-south-africa-a-comparative-risk-assessment-by-socioeconomic-status
#10
Charlotte Probst, Charles D H Parry, Jürgen Rehm
OBJECTIVES: To quantify HIV/AIDS mortality attributable to alcohol use in the adult general population of South Africa in 2012 by socioeconomic status (SES). DESIGN: Comparative risk assessment based on secondary individual data, aggregate data and risk relations reported in the literature. SETTING: South African adult general population. PARTICIPANTS: For metrics of alcohol use by SES, sex and age: 27 070 adults that participated in a nationally representative survey in 2012...
February 21, 2018: BMJ Open
https://www.readbyqxmd.com/read/29466531/association-of-increased-chronicity-of-depression-with-hiv-appointment-attendance-treatment-failure-and-mortality-among-hiv-infected-adults-in-the-united-states
#11
Brian W Pence, Jon C Mills, Angela M Bengtson, Bradley N Gaynes, Tiffany L Breger, Robert L Cook, Richard D Moore, David J Grelotti, Conall O'Cleirigh, Michael J Mugavero
Importance: Depression commonly affects adults with HIV and complicates the management of HIV. Depression among individuals with HIV tends to be chronic and cyclical, but the association of this chronicity with HIV outcomes (and the related potential for screening and intervention to shorten depressive episodes) has received little attention. Objective: To examine the association between increased chronicity of depression and multiple HIV care continuum indicators (HIV appointment attendance, treatment failure, and mortality)...
February 21, 2018: JAMA Psychiatry
https://www.readbyqxmd.com/read/29465640/context-appropriate-interventions-to-prevent-syphilis-a-narrative-review
#12
Thomas A Peterman, Susan Cha
BACKGROUND: The success of an intervention to prevent syphilis will depend on the context and the goal of the intervention. To help programs choose interventions, we reviewed major changes in context and types of interventions that may be effective. METHODS: We reviewed the literature on the changing context of syphilis in the United States and interventions to prevent syphilis, focusing on papers that included evidence of effectiveness. RESULTS: Populations acquiring syphilis are constantly changing...
February 13, 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29465589/high-dose-tigecycline-for-the-treatment-of-nosocomial-carbapenem-resistant-klebsiella-pneumoniae-bloodstream-infections-a-retrospective-cohort-study
#13
Ting-Ting Geng, Xin Xu, Man Huang
Carbapenem-resistant Klebsiella pneumoniae (CRKP) bloodstream infection (BSI) has become increasingly frequent threat recently, especially in the intensive care unit (ICU). High-dose tigecycline (TGC) regimen is proposed due to the limitation of treatment options. We investigated the efficacy and safety of high-dose TGC combination regimens for treating CRKP BSI. Furthermore, the risk factors for mortality were also determined.This was a single center retrospective cohort study conducted from 2014 to 2016. A total of 40 patients with nosocomial CRKP BSI admitted to the ICU were included; they were classified into two groups according to the treatment regimens with high-dose TGC (HD group) or not (non-HD group)...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29465370/the-initial-predictors-of-death-in-153-patients-with-anca-associated-vasculitis-in-a-single-korean-centre
#14
Chin Hee Moon, Juyoung Yoo, Seung Min Jung, Jason Jungsik Song, Yong-Beom Park, Sang-Won Lee
OBJECTIVES: We estimated the cumulative patient survival rates, the causes of death and the initial predictors of death in Korean patients with microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA) and eosinophilic GPA (EGPA). METHODS: We reviewed the medical records of 153 patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). We collected clinical and laboratory data including ANCA, Birmingham vasculitis activity score (BVAS), five factor score (FFS) (2009), comorbidities, medications and prognosis (death and relapse)...
February 14, 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29465002/prognostic-and-diagnostic-value-of-elevated-serum-concentration-of-procalcitonin-in-patients-with-suspected-heart-failure-a-review-and-meta-analysis
#15
Linda Aïssou, Emmanuel Sorbets, Elisa Lallmahomed, François-Xavier Goudot, Natalia Pop, Sanae Es-Sebbani, Leïla Benouda, Gregory Nuel, Christophe Meune
PURPOSE: The diagnostic and prognostic significance of procalcitonin remains uncertain in HF patients. We reviewed and performed a meta-analysis of studies that measured PCT in HF patients, with or without infection. MATERIALS AND METHODS: We identified 7 studies (9,514 patients, 5,810 with diagnoses of HF) eligible for our analysis, out of 247 examined. We estimated the serum PCT concentrations in patients with and without HF and/or infection, and examined the mortality rates of patients with versus without elevated serum PCT concentrations...
February 21, 2018: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/29464834/increasing-incidence-of-hiv-associated-tuberculosis-in-romanian-injecting-drug-users
#16
C Oprea, I Ianache, P I Calistru, M Nica, S Ruta, C Smith, M Lipman
BACKGROUND: A high prevalence of tuberculosis (TB) among HIV-positive injecting drug users (IDUs) may fuel the TB epidemic in the general population of Romania. We determined the frequency and characteristics of TB in HIV-infected IDUs referred to a national centre. METHODS: Prospective observational cohort study of all newly-diagnosed HIV-positive IDUs admitted to Victor Babes Hospital, Bucharest, between January 2009 and December 2014. Socio-demographics, clinical characteristics and outcomes of HIV/TB co-infected IDUs were compared to HIV-positive IDUs without TB...
February 21, 2018: HIV Medicine
https://www.readbyqxmd.com/read/29464789/surgical-outcomes-of-mitral-valve-replacement-with-concomitant-mitral-annular-reconstruction
#17
Su Wan Kim, Dong Seop Jeong, Kiick Sung, Wook Sung Kim, Young Tak Lee, Pyo Won Park
BACKGROUND AND AIM OF THE STUDY: We evaluated the early and long-term outcomes of mitral annular reconstruction (MAR) with pericardium during mitral valve replacement (MVR), and analyzed the risk factors associated with post-operative mortality. METHODS: Between May 1997 and April 2013, 78 consecutive patients underwent MVR with MAR. The indications for MAR were treatment for annular infection in native valve endocarditis (n = 23, 29.5%) or prosthetic valve endocarditis (n = 26, 33...
February 20, 2018: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/29464345/prognostic-impact-of-bacterobilia-on-morbidity-and-postoperative-management-after-pancreatoduodenectomy-a-systematic-review-and-meta-analysis
#18
Benjamin Müssle, Sebastian Hempel, Christoph Kahlert, Marius Distler, Jürgen Weitz, Thilo Welsch
BACKGROUND: Intraoperative bile analysis during pancreatoduodenectomy (PD) is performed routinely at specialized centers worldwide. However, it remains controversial if and how intraoperative bacterobilia during PD affects morbidity and its management. The aim of the study was a systematic review and meta-analysis of intraoperative bacterobilia and its impact on patient outcome after PD. METHODS: Five relevant outcomes of interest were defined, and a systematic review of the literature with meta-analysis was performed according to the PRISMA guidelines...
February 20, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29464220/a-rare-cause-of-acute-abdomen-in-the-ed-chemotherapy-induced-pneumatosis-intestinalis
#19
Mesut Ozturk, Ilkay Camlidag, Mehmet Selim Nural, Gokhan Selcuk Ozbalci, Tumay Bekci
Pneumatosis intestinalis (PI) and portomesenteric venous gas (PVG) refers to the presence of air within the intestinal wall and portomesenteric vessels. Most of the time, it is associated with mesenteric ischemia that requires immediate surgical intervention as it has high mortality rate. It may also be seen secondary to various conditions, including infections, surgeries, and some chemotherapeutic drugs. A 61-year old-male was admitted to our emergency department complaining of abdominal pain after chemotherapy...
December 2017: Turkish Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29463745/rocaglates-as-dual-targeting-agents-for-experimental-cerebral-malaria
#20
David Langlais, Regina Cencic, Neda Moradin, James M Kennedy, Kodjo Ayi, Lauren E Brown, Ian Crandall, Michael J Tarry, Martin Schmeing, Kevin C Kain, John A Porco, Jerry Pelletier, Philippe Gros
Cerebral malaria (CM) is a severe and rapidly progressing complication of infection by Plasmodium parasites that is associated with high rates of mortality and morbidity. Treatment options are currently few, and intervention with artemisinin (Art) has limited efficacy, a problem that is compounded by the emergence of resistance to Art in Plasmodium parasites. Rocaglates are a class of natural products derived from plants of the Aglaia genus that have been shown to interfere with eukaryotic initiation factor 4A (eIF4A), ultimately blocking initiation of protein synthesis...
February 20, 2018: Proceedings of the National Academy of Sciences of the United States of America
keyword
keyword
36449
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"