keyword
MENU ▼
Read by QxMD icon Read
search

Pubmed

keyword
https://www.readbyqxmd.com/read/28806822/-multiple-myeloma-current-status-in-diagnostic-testing-and-therapy
#1
Michael Kehrer, Sebastian Koob, Andreas Strauss, Dieter Christian Wirtz, Jan Schmolders
Background Multiple myeloma is a haematological blood cancer of the bone marrow and is classified by the World Health Organisation (WHO) as a plasma cell neoplasm. In multiple myeloma, normal plasma cells transform into malignant myeloma cells and produce large quantities of an abnormal immunoglobulin called monoclonal protein or M protein. This ultimately causes multiple myeloma symptoms such as bone damage or kidney problems. The annual worldwide incidence of multiple myeloma is estimated to be 6 - 7/100,000 and accounts for 1% of all cancer...
August 14, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28806407/low-fermentable-oligosaccharides-disaccharides-monosaccharides-and-polyols-fodmap-diet-improves-symptoms-in-adults-suffering-from-irritable-bowel-syndrome-ibs-compared-to-standard-ibs-diet-a-meta-analysis-of-clinical-studies
#2
Péter Varjú, Nelli Farkas, Péter Hegyi, András Garami, Imre Szabó, Anita Illés, Margit Solymár, Áron Vincze, Márta Balaskó, Gabriella Pár, Judit Bajor, Ákos Szűcs, Orsolya Huszár, Dániel Pécsi, József Czimmer
BACKGROUND: Irritable bowel syndrome (IBS) and functional digestive tract disorders, e.g. functional bloating, carbohydrate maldigestion and intolerances, are very common disorders frequently causing significant symptoms that challenge health care systems. A low Fermentable Oligosaccharides, Disaccharides, Monosaccharides and Polyols (FODMAP) diet is one of the possible therapeutic approaches for decreasing abdominal symptoms and improving quality of life. OBJECTIVES: We aimed to meta-analyze data on the therapeutic effect of a low-FODMAP diet on symptoms of IBS and quality of life and compare its effectiveness to a regular, standard IBS diet with high FODMAP content, using a common scoring system, the IBS Symptom Severity Score (IBS-SSS)...
2017: PloS One
https://www.readbyqxmd.com/read/28806352/association-between-exposure-to-noise-and-risk-of-hypertension-a-meta-analysis-of-observational-epidemiological-studies
#3
Wenning Fu, Chao Wang, Li Zou, Qiaoyan Liu, Yong Gan, Shijiao Yan, Fujian Song, Zhihong Wang, Zuxun Lu, Shiyi Cao
OBJECTIVE: An increasing amount of original studies suggested that exposure to noise could be associated with the risk of hypertension, but the results remain inconsistent and inconclusive. We aimed to synthesize available epidemiological evidence about the relationship between various types of noise and hypertension, and to explore the potential dose-response relationship between them in an up-to-date meta-analysis. METHODS: We conducted a literature search of PubMed and Embase from these databases' inception through December 2016 to identify observational epidemiological studies examining the association between noise and risk of hypertension...
August 12, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28805984/self-medication-misuse-in-the-middle-east-a-systematic-literature-review
#4
REVIEW
Malak M Khalifeh, Nicholas D Moore, Pascale R Salameh
Regulations usually distinguish between prescription-only (POM) and over-the-counter (OTC) medicines. The former requires medical prescription; the latter are available for SM of common minor or easily treated ailments. However, in the Eastern Mediterranean countries, theoretical prescription medicines can easily be purchased without a prescription, as self-medication (SM) resulting in potential misuse and unnecessary risk for patients. The magnitude of this activity is uncertain. The aim of this article, therefore, is to undertake a comprehensive review to identify the different types of medicines that can easily be purchased as SM in Middle East and recognized as misused...
August 2017: Pharmacology Research & Perspectives
https://www.readbyqxmd.com/read/28805954/impact-of-caregiver-burden-on-mental-health-in-bereaved-caregivers-of-cancer-patients-a-systematic-review
#5
REVIEW
Julia Große, Julia Treml, Anette Kersting
BACKGROUND: Although caregiver burden may continue to influence the mental health of cancer patients' caregivers long after bereavement few studies have examined this issue. METHODS: A systematic review was conducted to provide a summary of (1) operationalizations of caregiver burden used in this field and (2) the effect of caregiver burden on post-bereavement mental health of adult caregivers of cancer patients. A systematic search of the electronic databases PubMed, Web of Science, and PsycINFO was conducted across empirical studies published in a peer-reviewed journal up until April 2017...
August 14, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28805341/treatment-options-for-severe-pulmonary-embolism-during-pregnancy-and-the-postpartum-period-a-systematic-review
#6
G Martillotti, F Boehlen, H Robert-Ebadi, N Jastrow, M Righini, M Blondon
BACKGROUND: Massive pulmonary embolism (PE) during pregnancy or the postpartum period is a rare but dramatic event. Our aim was to systematically review the evidence to guide its management. METHODS: We searched Pubmed, Embase, conference proceedings and the RIETE registry for published cases of severe (submassive/massive) PE treated with thrombolysis, percutaneous or surgical thrombectomy and/or with ECMO, occurring during pregnancy or within 6 weeks of delivery...
August 14, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28805310/use-of-direct-oral-anticoagulants-for-stroke-prevention-in-elderly-patients-with-nonvalvular-atrial-fibrillation
#7
Lynn B Oertel, Annemarie E Fogerty
BACKGROUND AND PURPOSE: Four direct oral anticoagulants (DOACs) are available for the prevention of stroke in nonvalvular atrial fibrillation (NVAF): dabigatran (a direct thrombin inhibitor); and rivaroxaban, apixaban, and edoxaban (factor Xa inhibitors). This article summarizes the safety and efficacy of DOACs for the prevention of stroke in elderly NVAF patients. METHODS: PubMed was searched to identify published results of randomized, controlled trials evaluating DOACs for stroke prevention in elderly NVAF patients...
August 14, 2017: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/28805298/female-urethral-injuries-associated-with-pelvic-fracture-a-systematic-review-of-the-literature
#8
REVIEW
Devin N Patel, Cynthia S Fok, George D Webster, Jennifer T Anger
OBJECTIVES: To systematically review the literature of female urethral injuries associated with pelvic fracture and determine optimal management of this rare injury. MATERIALS AND METHODS: Using Meta-analysis Of Observational Studies in Epidemiology criteria, we searched Cochrane, Pubmed and OVID databases for all articles available before June 30, 2016 using the terms "female pelvic fracture urethroplasty," "female urethral distraction," "female pelvic fracture urethral injury," "female pelvic fracture urethra girls...
August 14, 2017: BJU International
https://www.readbyqxmd.com/read/28805255/mandibular-complete-denture-versus-single-implant-overdenture-a-systematic-review-of-patient-reported-outcomes
#9
REVIEW
Túlio Eduardo Nogueira, Danilo Rocha Dias, Cláudio Rodrigues Leles
The single-implant mandibular overdenture (SIMO) has been proposed as an alternative for edentulous patients who are poorly adapted to their dentures due to low retention and stability of the conventional mandibular complete denture (CD). However, there is a lack of evidence regarding the effectiveness of SIMO, which can be measured by examining patient perception of treatment effects. The aim of this systematic review was to assess the comparative results of CD and SIMO treatments by using patient-reported outcome measures...
August 14, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28805246/associations-between-belief-inflexibility-and-dimensions-of-delusions-a-meta-analytic-review-of-two-approaches-to-assessing-belief-flexibility
#10
Chen Zhu, Xiaoqi Sun, Suzanne Ho-Wai So
OBJECTIVES: Belief inflexibility has been suggested to maintain delusions. Different measures of assessing belief inflexibility have been developed, and it remains unclear whether patients with delusions display belief inflexibility similarly across measures. As delusions consist of multiple dimensions, the aim of this meta-analytic review was to examine how belief inflexibility is related to different aspects of delusions (conviction, distress, and preoccupation) and to compare these associations between interview-based and task-based measures of belief inflexibility...
August 14, 2017: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28805188/managing-faecal-incontinence-in-people-with-advanced-dementia-resident-in-care-homes-finch-study-a-realist-synthesis-of-the-evidence
#11
Claire Goodman, Christine Norton, Marina Buswell, Bridget Russell, Danielle Harari, Rowan Harwood, Brenda Roe, Jo Rycroft-Malone, Vari M Drennan, Mandy Fader, Michelle Maden, Karen Cummings, Frances Bunn
BACKGROUND: Eighty per cent of care home residents in the UK are living with dementia. The prevalence of faecal incontinence (FI) in care homes is estimated to range from 30% to 50%. There is limited evidence of what is effective in the reduction and management of FI in care homes. OBJECTIVE: To provide a theory-driven explanation of the effectiveness of programmes that aim to improve FI in people with advanced dementia in care homes. DESIGN: A realist synthesis...
August 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28805179/psychosis-as-a-risk-factor-for-suicidal-thoughts-and-behaviors-a-meta-analysis-of-longitudinal-studies
#12
X Huang, K R Fox, J D Ribeiro, J C Franklin
BACKGROUND: Research has long noted higher prevalence rates of suicidal thoughts and behaviors among individuals with psychotic symptoms. Major theories have proposed several explanations to account for this association. Given the differences in the literature regarding the operationalization of psychosis and sample characteristics, a quantitative review is needed to determine to what extent and how psychosis confers risk for suicidality. METHODS: We searched PsycInfo, PubMed, and GoogleScholar for studies published before 1 January 2016...
August 14, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28805088/the-current-therapeutic-options-for-crohn-s-disease-from-medical-therapy-to-intestinal-transplantation
#13
Augusto Lauro, Francesco D'Amico, Gabriel Gondolesi
Crohn's disease (CD) has an annual incidence per 100.000 person-year of 20.2 in North America and 12.7 in Europe, and the purpose of this review is to evaluate its medical management, from diagnosis to transplant. Pharmacologic manipulation with nutritional care aims to achieve and maintain remission, but more than half of patients will undergo an intestinal resection, very often repeated over time. They could experience short bowel syndrome (SBS) requiring total parenteral nutrition (TPN). Intestinal transplantation (ITx) represents an alternative in case of irreversible intestinal failure (IF) with life-threatening TPN complications...
August 14, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28804959/head-to-head-comparison-of-prasugrel-versus-ticagrelor-in-patients-undergoing-percutaneous-coronary-intervention-a-meta-analysis-of-randomized-controlled-trials
#14
Ryota Sakurai, Ivana Burazor, Heidi N Bonneau, Hideaki Kaneda
OBJECTIVES: We sought to compare the efficacy and safety of prasugrel and ticagrelor in patients with coronary artery disease undergoing percutaneous coronary intervention (PCI). BACKGROUND: Evidence from randomized head-to-head comparison between prasugrel and ticagrelor is rare regarding clinical endpoints. METHODS: PubMed, the Cochrane Library, and Web of Science were queried with the terms "prasugrel," "ticagrelor," and "randomized." Relevant randomized controlled trials (RCTs) or the same terms were also surveyed using clinicaltrials...
August 13, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/28804874/high-frequency-jet-ventilation-for-motion-management-during-ablation-procedures-a-narrative-review
#15
REVIEW
K Galmén, P Harbut, J Freedman, J G Jakobsson
BACKGROUND: High frequency jet ventilation (HFJV) is a method of ventilation that has gained renewed interest over the recent years as it can reduce organ movement to near static conditions, thus enhancing surgical precision in minimal invasive procedures, for example, ablation procedures for atrial fibrillation and solid organ tumours. The aim of this review was to create a summary of the current evidence concerning the clinical use of HFJV for ablative procedures. METHOD: PubMed was searched for the key words high frequency ventilation and ablation January 1990-December 2016...
August 13, 2017: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/28804860/temperature-drop-and-the-risk-of-asthma-a-systematic-review-and-meta-analysis
#16
Xiaowei Cong, Xijin Xu, Yuling Zhang, Qihua Wang, Long Xu, Xia Huo
The relationship between asthma and temperature changes remains controversial. The aim of this study was to investigate the association between temperature changes and the risk of asthma. A total of 26 studies (combined total number of subjects N > 26 million), covering 13 countries and Costa Rica, were identified by using a series of keywords in different combinations and searching the papers in PubMed, EMBSEA, Web of Science, MEDLINE, AIM, LILACS, and WPRIM before February 2016. Most of the papers were published in English...
August 13, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28804813/a-systematic-review-of-the-clinical-applications-and-complications-of-bone-marrow-aspirate-concentrate-in-management-of-bone-defects-and-nonunions
#17
REVIEW
Mohamed A Imam, James Holton, Lukas Ernstbrunner, Wojciech Pepke, Florian Grubhofer, Ali Narvani, Martyn Snow
PURPOSE: Fracture healing encompasses a succession of dynamic multifactorial metabolic events, which ultimately re-establishes the integrity of the biomechanical properties of the bone. Up to 10% of the fractures occurring annually will need additional surgical procedures because of impaired healing. The aim of this article is to review the current literature regarding the use of bone marrow aspirate concentrate (BMAC) and its effectiveness in the management of bone defects. METHODS: We have included all published clinical literature investigating the development, techniques and applications of BMAC...
August 13, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28804704/hypoxia-in-cervical-cancer-from-biology-to-imaging
#18
REVIEW
Heidi Lyng, Eirik Malinen
PURPOSE: Hypoxia imaging may improve identification of cervical cancer patients at risk of treatment failure and be utilized in treatment planning and monitoring, but its clinical potential is far from fully realized. Here, we briefly describe the biology of hypoxia in cervix tumors of relevance for imaging, and evaluate positron emission tomography (PET) and magnetic resonance imaging (MRI) techniques that have shown promise for assessing hypoxia in a clinical setting. We further discuss emerging imaging approaches, and how imaging can play a role in future treatment strategies to target hypoxia...
2017: Clinical and Translational Imaging: Reviews in Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28804703/hybrid-intraoperative-imaging-techniques-in-radioguided-surgery-present-clinical-applications-and-future-outlook
#19
REVIEW
S L Bugby, J E Lees, A C Perkins
PURPOSE: This review aims to summarise the hybrid modality radioguidance techniques currently in clinical use and development, and to discuss possible future avenues of research. Due to the novelty of these approaches, evidence of their clinical relevance does not yet exist. The purpose of this review is to inform nuclear medicine practitioners of current cutting edge research in radioguided surgery which may enter standard clinical practice within the next 5-10 years. Hybrid imaging is of growing importance to nuclear medicine diagnostics, but it is only with recent advances in technology that hybrid modalities are being investigated for use during radioguided surgery...
2017: Clinical and Translational Imaging: Reviews in Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28803934/doses-durations-and-gender-predict-vancomycin-induced-kidney-injury-in-pre-clinical-studies
#20
J Nicholas O'Donnell, Nathaniel J Rhodes, Cristina M Miglis, Lejla Catovic, Jiajun Liu, Cameron Cluff, Gwen Pais, Sean Avedissian, Medha Joshi, Brooke Griffin, Walter Prozialeck, Anil Gulati, Thomas P Lodise, Marc H Scheetz
Background While vancomycin's exposure-dependent efficacy thresholds have been probed, less is known regarding acute kidney injury (AKI) thresholds for vancomycin. Sensitive urinary biomarkers such as Kidney injury molecule 1 (KIM-1) have shown high sensitivity and specificity for vancomycin-associated AKI. We sought to determine if dose-response curves existed with urinary KIM-1. Secondarily, we sought to evaluate the impact of therapy duration and gender status on observed relationships. Methods A systematic review was conducted via PubMed/MEDLINE...
August 10, 2017: International Journal of Antimicrobial Agents
keyword
keyword
3644
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"