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https://www.readbyqxmd.com/read/27917579/novel-technique-for-repigmentation-of-senescence-grey-hair
#1
Andy Goren, Željana Bolanča, Torello Lotti, Mirna Šitum
No abstract text is available yet for this article.
December 5, 2016: Dermatologic Therapy
https://www.readbyqxmd.com/read/27904182/comparative-study-of-efficacy-of-epidermal-melanocyte-transfer-versus-hair-follicular-melanocyte-transfer-in-stable-vitiligo
#2
Navya Donaparthi, Ajay Chopra
BACKGROUND: Vitiligo surgery has come up a long way from punch skin grafts to epidermal cell suspension and latest to the extracted hair follicle outer root sheath cell suspension (EHFORSCS) transplantation. The progressive development from one technique to the other is always on a quest for the best. In the latest development, EHFORSCS, which is an enriched source of follicular inactive melanocyte (melanocyte stem cells), seems to be a good addition to the prevailing cell-based therapies for vitiligo...
November 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27882588/clinical-and-epidemiological-analysis-in-149-cases-of-rhododendrol-induced-leukoderma
#3
Momoko Yoshikawa, Yasuyuki Sumikawa, Tokimasa Hida, Takafumi Kamiya, Kimi Kase, Yasue Ishii-Osai, Junji Kato, Yuji Kan, Shiori Kamiya, Yuki Sato, Toshiharu Yamashita
Rhododendrol-induced leukoderma is an acquired depigmentation that develops mainly at the contact site after repeated use of skin-whitening cosmetics containing rhododendrol. In most cases, cessation of further depigmentation or occurrence of repigmentation is observed after discontinuing the use of cosmetics. However, some patients develop vitiligo vulgaris through the spread of depigmentation into the non-exposed areas. Our study aims to investigate the patient-specific factors that may affect the extent of depigmentation or repigmentation, as well as development of vitiligo vulgaris...
November 24, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27878842/pharmacologic-treatment-of-vitiligo-in-children-and-adolescents-a-systematic-review
#4
REVIEW
Andreia Freire de Menezes, Fernanda Oliveira de Carvalho, Rosana S S Barreto, Bruno de Santana Silva, Saravanan Shanmugam, Ricardo Queiroz Gurgel, Adriano Antunes de Souza Araújo
BACKGROUND: The true pathogenic mechanism of vitiligo is still unknown. About half of the patients with this disease have onset before the age of 20 years, making it a serious dermatologic disorder in childhood. OBJECTIVES: The objective of this study was to review the literature in a systematic way and identify the main pharmacologic treatments and outcomes in children and adolescents with vitiligo. METHODS: Four databases-the National Library of Medicine (MEDLINE-PubMed), Web of Science, Scopus, and Latin American and Caribbean Health Sciences (LILACS)-were used for the search up to January 2015...
November 23, 2016: Pediatric Dermatology
https://www.readbyqxmd.com/read/27864868/repigmentation-in-vitiligo-position-paper-of-the-vitiligo-global-issues-consensus-conference-vgicc
#5
Emily Yiping Gan, Viktoria Eleftheriadou, Samia Esmat, Iltefat Hamzavi, Thierry Passeron, Markus Böhm, Tag Anbar, Boon Kee Goh, Cheng-Che Eric Lan, Harvey Lui, M Ramam, Noufal Raboobee, Ichiro Katayama, Tamio Suzuki, Davinder Parsad, Vaneeta Seth, Henry W Lim, Nanja van Geel, Sanjeev Mulekar, John Harris, Richard Wittal, Laila Benzekri, Yvon Gauthier, Prasad Kumarasinghe, Steven Tien Guan Thng, Caio Cesar Silva de Castro, Marwa Abdallah, Charlotte Vrijman, Marcel Bekkenk, Julien Seneschal, Amit G Pandya, Khaled Ezzedine, Mauro Picardo, Alain Taïeb
The Vitiligo Global Issues Consensus Conference (VGICC), through an international e-Delphi consensus, concluded that "repigmentation" and "maintenance of gained repigmentation" are essential core outcome measures in future vitiligo trials. This VGICC position paper addresses these core topics in two sections and includes an atlas depicting vitiligo repigmentation patterns and color match. The first section delineates mechanisms and characteristics of vitiligo repigmentation and the second summarizes the outcomes of international meeting discussions and two e-surveys on vitiligo repigmentation, which had been carried out over three years...
November 19, 2016: Pigment Cell & Melanoma Research
https://www.readbyqxmd.com/read/27835917/-autologous-skin-cell-transplantation-and-medical-needling-for-repigmentation-of-depigmented-burn-scars-on-uv-protected-and-uv-exposed-skin
#6
K H Busch, R Bender, N Walezko, H Aziz, M A Altintas, M C Aust
Background: Burn scars remain a serious physical and psychological problem for the affected people. Both clinical studies and basic scientific research have shown that medical needling can significantly increase the quality of burn scars with comparatively low risk and stress for the patient related to skin elasticity, moisture, erythema and transepidermal water loss. However, medical needling does not influence repigmentation of large hypopigmented scars. Objective: The goal is to evaluate whether both established methods - needling (improvement of scar quality) and non-cultured autologous skin cell suspension (NCASCS) "ReNovaCell" (repigmentation) - can be combined...
November 11, 2016: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/27813161/successful-treatment-of-vitiligo-on-the-scalp-of-a-9-year-old-girl-using-autologous-cultured-pure-melanocyte-transplantation
#7
Xin-Gang Wu, Ai-E Xu
Leukotrichia frequently accompanies vitiligo on hairy areas such as the scalp. Treatment with conventional medical therapy is usually unsuccessful because of deficiencies in the melanocyte reservoir. We describe transplantation of autologous cultured pure melanocytes for scalp vitiligo with leukotrichia in a 9-year-old girl, resulting in almost complete and stable repigmentation of skin and hair.
November 4, 2016: Pediatric Dermatology
https://www.readbyqxmd.com/read/27806525/clinical-effectiveness-of-gingival-depigmentation-using-conventional-surgical-scrapping-and-diode-laser-technique-a-quasi-experimental-study
#8
Raghavendra Reddy Nagati, M Ragul, Nabeeh A Al-Qahtani, K S Ravi, S Tikare, Mohan Kumar Pasupuleti
Excessive gingival pigmentation is a major aesthetic concern in modern society, though it is not a medical problem they consider it as a negative attribute. Patients with gingival hyperpigmentation usually complain and request cosmetic therapy, particularly if the pigmentation is visible during speaking and smiling. Various depigmentation methods, including burr abrasion, cryosurgery, electro-surgery, split thickness flap excision and surgical scraping techniques have been used with varying degrees of success...
August 1, 2016: Global Journal of Health Science
https://www.readbyqxmd.com/read/27785821/paradoxically-dark-spontaneous-repigmentation-a-rare-complication-of-generalized-vitiligo
#9
LETTER
S Agrawal, D A Porto, H W Lim
No abstract text is available yet for this article.
October 27, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27784078/interventions-for-vitiligo
#10
COMMENT
Khaled Ezzedine, Maxine Whitton, Mariona Pinart
Clinical Question: Which interventions are associated with highest efficacy and fewest adverse events for treating vitiligo? Bottom Line: Combination therapies, particularly those involving some form of light (ie, narrowband UV-B) were associated with more improved repigmentation than monotherapies. There was limited evidence to support the association of UV-A alone and UV-B alone with repigmentation for vitiligo. There was moderate evidence to support the association of UV-A and UV-B, when used in combination with psoralens, topical corticosteroids, vitamin D analogues, fluorouracil, azathioprine, and oral prednisolone with improved outcomes for vitiligo...
October 25, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27745746/chemical-leukoderma-associated-with-methylphenidate-transdermal-system-data-from-the-us-food-and-drug-administration-adverse-event-reporting-system
#11
Carmen Cheng, Lois La Grenade, Ida-Lina Diak, Allen Brinker, Robert L Levin
OBJECTIVE: To identify and characterize cases of chemical leukoderma, an underrecognized adverse event, associated with the methylphenidate transdermal system (MTS) reported to the US Food and Drug Administration Adverse Event Reporting System (FAERS). STUDY DESIGN: We searched the Food and Drug Administration Adverse Event Reporting System for reports of chemical leukoderma associated with MTS, received by the Food and Drug Administration from April 6, 2006 to December 23, 2014...
October 10, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27699846/treatment-of-childhood-vitiligo-using-tacrolimus-ointment-with-narrowband-ultraviolet-b-phototherapy
#12
Surabhi Dayal, Priyadarshini Sahu, Nidhi Gupta
BACKGROUND/OBJECTIVES: A combination of narrowband ultraviolet B (NBUVB) phototherapy plus topical tacrolimus has been used in adult vitiligo but has not yet been explored in children. We therefore sought to highlight the efficacy of this synergistic combination in childhood vitiligo. The objective was to study the clinical efficacy and safety of a combination of NBUVB with topical tacrolimus ointment 0.03% in childhood vitiligo. METHOD: In this open-label study, 20 children, 4 to 14 years of age, with symmetrical vitiligo lesions were enrolled for 24 weeks...
October 4, 2016: Pediatric Dermatology
https://www.readbyqxmd.com/read/27696531/effect-of-narrow-band-ultraviolet-b-phototherapy-as-monotherapy-or-combination-therapy-for-vitiligo-a-meta-analysis
#13
Ronghua Li, Meng Qiao, Xiaoyan Wang, Xintong Zhao, Qing Sun
BACKGROUND: The treatment of vitiligo is still one of the most difficult dermatological challenges, although there are many therapeutic options. Narrow band ultraviolet B (NB-UVB) phototherapy is considered to be a very important modality for generalized vitiligo. OBJECTIVE: The aim of this study was to explore whether a combination of NB-UVB and topical agents would be superior to NB-UVB alone for treating vitiligo. METHODS: We searched the electronic databases such as PUBMED, EMBASE, Cochrane Library and Web of Science...
October 1, 2016: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/27640798/-not-available
#14
Li Lei, Jinhua Huang, Qinghai Zeng, Caiyun Xi, Aiyuan Guo, Jing Chen
OBJECTIVE: To evaluate the efficacy and influential factors for 308 nm excimer laser in the treatment of stable vitiligo patients.
 METHODS: A total of 207 stable vitiligo patients with 1 763 patches were treated with 308 nm excimer laser. Open-label study was carried out to investigate the efficacy and safety regarding the treatment with 308 nm excimer laser, and to compare the response under different conditions including gender, age, duration, lesion location, and hair color...
September 28, 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/27638439/portable-home-phototherapy-for-vitiligo
#15
Viktoria Eleftheriadou, Khaled Ezzedine
Vitiligo is the most common depigmentation disorder, affecting around 1% of population worldwide. There is no cure, and no firm clinical recommendations can be made for the treatment of vitiligo. A European guideline suggests early treatment of small lesions of recent onset and childhood vitiligo with combination of phototherapy and topical agents. Suitable facilities and equipment, such as hand-held portable phototherapy devices, are needed, if this new guideline is to be implemented. Hand-held units are suitable for small lesions, making phototherapy available for patients with limited and/or early vitiligo...
September 2016: Clinics in Dermatology
https://www.readbyqxmd.com/read/27638438/phototherapy-the-vitiligo-management-pillar
#16
Samia Esmat, Wedad Mostafa, Rehab A Hegazy, Suzan Shalaby, Vaneeta Sheth, Randa Youssef, Medhat El-Mofty
Phototherapy has been the mainstay of vitiligo therapy for several decades. A variety of wavelengths and modalities are available, but narrowband ultraviolet B remains the safest and most commonly used treatment. Acting on multiple steps in vitiligo pathogenesis, narrowband ultraviolet B is one of the few therapies that can effectively induce stabilization and stimulate repigmentation. Achievement of optimal results involves using a combination of appropriate treatment protocols, careful patient selection, and patient education to set expectations...
September 2016: Clinics in Dermatology
https://www.readbyqxmd.com/read/27635239/recent-advances-in-understanding-vitiligo
#17
REVIEW
Prashiela Manga, Nada Elbuluk, Seth J Orlow
Vitiligo, an acquired depigmentation disorder, manifests as white macules on the skin and can cause significant psychological stress and stigmatization. Recent advances have shed light on key components that drive disease onset and progression as well as therapeutic approaches. Vitiligo can be triggered by stress to the melanin pigment-producing cells of the skin, the melanocytes. The triggers, which range from sunburn to mechanical trauma and chemical exposures, ultimately cause an autoimmune response that targets melanocytes, driving progressive skin depigmentation...
2016: F1000Research
https://www.readbyqxmd.com/read/27632965/repigmentation-patterns-in-vitiligo-where-do-we-stand
#18
A Bishnoi, D Parsad
No abstract text is available yet for this article.
September 2016: British Journal of Dermatology
https://www.readbyqxmd.com/read/27627998/repigmentation-patterns-induced-by-nb-uvb-and-their-relationship-with-melanocytic-migration-and-proliferation-in-vitiligo
#19
Juan Pablo Castanedo-Cázares, Juan Diego Cortés-García, Cornelia Fuentes-Ahumada, Karla Martinez-Rosales, Bertha Torres-Álvarez
BACKGROUND/PURPOSE: Vitiligo is the most commonly acquired depigmentation disorder of the skin and is characterized by the destruction of melanocytes. Ultraviolet phototherapy with narrow band (UVB-NB) induces proliferation, differentiation, maturation, and migration of melanocytes. The clinical repigmentation is featured by follicular, marginal, and diffuse patterns. The aim of this study was to observe the process involved in the melanocyte migration and proliferation among these patterns and the unresponsive lesions following UVB-NB phototherapy...
September 2016: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/27601864/restoration-of-pigmentation-by-follicular-unit-extraction-transplant-in-three-cases-of-focal-vitiligo-recalcitrant-to-therapy-including-with-previous-nonculture-melanocyte-keratinocyte-transplant
#20
Shruti Mohankumar Menon, Yugal K Sharma, Prakhar Bansal, Shruti S Ghadgepatil
Vitiligo is an acquired, idiopathic depigmentary disease resisting satisfactory repigmentation despite multimodal therapy. Based on the concept of activation of the existing undifferentiated stem cells in the outer root sheet of the hair follicles, follicular unit extraction (FUE) transplant is an interesting advancement in the field of minimally invasive surgery for vitiligo. We herein present three cases of vitiligo whose residual recalcitrant foci as well as poliosis - refractory to therapy including with previous nonculture melanocyte-keratinocyte transplant - repigmented satisfactorily after FUE transplant...
April 2016: International Journal of Trichology
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