keyword
MENU ▼
Read by QxMD icon Read
search

CXL thin cornea

keyword
https://www.readbyqxmd.com/read/28926888/-accelerated-transepithelial-corneal-collagen-cross-linking-for-progressive-keratoconus-with-a-thin-cornea-one-year-results
#1
Z R Lin, H P Wu, S R Luo, Z S Liu, N Dong, X M Shang, Z W Xie, L Yan, X Fang
Objective: To evaluate the clinical results of keratoconic eyes with a thin cornea treated with accelerated transepithelial corneal collagen cross-linking (A-TE-CXL) within 1 year. Methods: Nineteen eyes of 19 patients with progressive keratoconus with a minimum corneal thickness from 380 μm to 420 μm (including the epithelium) were included in this prospective, nonrandomized clinical study and treated with A-TE-CXL. Scoring of pain and foreign body sensation, slit lamp examination, uncorrected visual acuity, best corrected distance visual acuity, corneal topography, anterior segment optical coherence tomography, in vivo corneal confocal microscopy and endothelial cell count were assessed before surgery and at 1, 3, 6 and 12 months postoperatively...
September 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28811773/transepithelial-corneal-crosslinking-in-treatment-of-progressive-keratoconus-12-months-clinical-results
#2
Bushra Akbar, Rana Intisar-Ul-Haq, Mazhar Ishaq, Sabahat Arzoo, Kashif Siddique
OBJECTIVE: The purpose of this study was to evaluate the safety and efficacy of transepithelial corneal collagen cross linking (TE-CXL) with modified riboflavin and accelerated UVA irradiance in thin corneas with pachymetry less than 400 microns at thinnest point, untreatable by epithelium off corneal collagen cross linking (CXL) in adult Pakistani population with progressive keratoconus. METHODS: This quasi experimental study included twenty six eyes of 26 patients with progressive keratoconus who underwent accelerated transepithelial CXL in Armed forced institute of ophthalmology with 12 months follow up...
May 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28761323/the-comparative-safety-of-genipin-versus-uva-riboflavin-crosslinking-of-rabbit-corneas
#3
Wenjing Song, Yun Tang, Jing Qiao, Haili Li, Bei Rong, Songlin Yang, Yuan Wu, Xiaoming Yan
PURPOSE: To investigate, after 24 h, the safety of genipin or ultraviolet A (UVA)-riboflavin crosslinking of keratocytes and endothelial cells. METHODS: Fifteen New Zealand white rabbits were selected and divided into a PBS group (five rabbits), a 0.2% genipin crosslinking (GP-CXL) group (five rabbits), and a UVA-riboflavin crosslinking (UVA-CXL) group (five rabbits). In the GP-CXL and PBS groups, 0.2% genipin or PBS was applied to the corneal surface of the right eyes...
2017: Molecular Vision
https://www.readbyqxmd.com/read/28644862/high-intensity-corneal-collagen-crosslinking-with-riboflavin-and-uva-in-rat-cornea
#4
Yirui Zhu, Peter S Reinach, Hanlei Zhu, Qiufan Tan, Qinxiang Zheng, Jia Qu, Wei Chen
Corneal collagen cross-linking (CXL) halts human corneal ectasias progression by increasing stromal mechanical stiffness. Although some reports describe that this procedure is effective in dealing with some infectious and immunologic corneal thinning diseases, there is a need for more animal models whose corneal thickness more closely resemble those occurring in these patients. To meet this need, we describe here high-intensity protocols that are safe and effective for obtaining CXL in rat corneas. Initially, a range of potentially effective UVA doses were evaluated based on their effectiveness in increasing tissue enzymatic resistance to dissolution...
2017: PloS One
https://www.readbyqxmd.com/read/28435217/patient-selection-for-corneal-collagen-cross-linking-an-updated-review
#5
REVIEW
Virgilio Galvis, Alejandro Tello, Alvaro I Ortiz, Luis C Escaf
Corneal cross-linking (CXL) is an option that in the last decade has demonstrated its efficacy and safety in halting the progression of keratoconus (KCN) and other corneal ectasias. Its indication has been extended beyond the classic definition that required evidence of KCN progression, especially in the presence of some risk factors for a possible progression (particularly the younger age). However, the results can be still somewhat variable today. There are several protocols, each with its own advantages and disadvantages...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28341606/safety-and-efficacy-of-sequential-intracorneal-ring-segment-implantation-and-cross-linking-in-pediatric-keratoconus
#6
Youssef Abdelmassih, Sylvain El-Khoury, Ali Dirani, Rafic Antonios, Ali Fadlallah, Carole G Cherfan, Elias Chelala, Elias F Jarade
PURPOSE: To evaluate the safety and visual outcome of intracorneal ring segment (ICRS) implantation followed by cross-linking in pediatric keratoconus patients. DESIGN: Retrospective interventional case series. METHODS: This retrospective study included pediatric patients (aged ≤14 years) with keratoconus and poor corrected distance visual acuity (CDVA) that underwent ICRS implantation and cross-linking (CXL). ICRS were inserted under topical anesthesia after creating a corneal tunnel with a femtosecond laser...
June 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28299302/cornea-collagen-cross-linking-for-keratoconus-a-comparison-between-accelerated-and-conventional-methods
#7
Hasan Razmjoo, Alireza Peyman, Ali Rahimi, Hoda Jafari Modrek
BACKGROUND: Keratoconus is a progressive degenerative disorder of the cornea in which structural changes in the cornea cause it to become thin and conical in shape. Recently, collagen cross-linking (CXL) has been introduced as an effective intervention in management of progressive keratoconus. Accelerated CXL is a new protocol of this procedure which reduces corneal ultraviolet irradiation exposure time to 5 min. This study aimed to compare visual acuity, keratometry and topographic criteria of keratoconic eyes after conventional and accelerated CXL with a six-month follow-up...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/27910295/combined-application-of-prophylactic-corneal-cross-linking-and-laser-in-situ-keratomileusis-a-review-of-literature
#8
REVIEW
Tommy C Y Chan, Alex L K Ng, Karen K W Chan, George P M Cheng, Ian Y H Wong, Vishal Jhanji
Laser in-situ keratomileusis (LASIK) is safe and effective laser refractive procedures in treating refractive errors. However, regression of treatment and iatrogenic keratectasia remain to be a major concern, especially in treating thin cornea with high ametropia. Collagen cross-linking (CXL) is an effective method in stopping keratoconus progression through increasing the biomechanical strength of the cornea. Adjuvant cross-linking to refractive procedures can theoretically help prevent regression and reduce the risk of keratectasia development by increasing the mechanical stability of cornea...
December 2, 2016: Acta Ophthalmologica
https://www.readbyqxmd.com/read/27900926/-corneal-cross-linking-as-a-treatment-for-progressive-keratoconus
#9
R P L Wisse, N Soeters, D A Godefrooij, N G de Koning-Tahzib
Keratoconus is a corneal disease with onset typically occurring during puberty or early adulthood. The cornea progressively thins and acquires a cone-like shape which negatively affects visual acuity. In the early stages, visual acuity can be corrected with glasses or contact lenses. In more advanced cases, a corneal transplant is ultimately indicated to restore visual acuity. Corneal cross-linking (CXL) is a treatment given at a relatively early stage that protects patients against deterioration of visual acuity and further corneal deformation in progressive cases of keratoconus...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27492105/natural-history-of-corneal-haze-after-corneal-collagen-crosslinking-in-keratoconus-using-scheimpflug-analysis
#10
Bia Z Kim, Charlotte A Jordan, Charles N J McGhee, Dipika V Patel
PURPOSE: To analyze corneal haze after corneal collagen crosslinking (CXL) for progressive keratoconus using Scheimpflug densitometry. SETTING: Auckland District Health Board, Auckland, New Zealand. DESIGN: Prospective randomized controlled study. METHODS: Both eyes of all patients were examined preoperatively and 1, 3, 6, and 12 months postoperatively. One eye of each patient was treated with corneal CXL, with the contralateral eye serving as the control...
July 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27293413/corneal-melting-after-collagen-cross-linking-for-keratoconus-in-a-thin-cornea-of-a-diabetic-patient-treated-with-topical-nepafenac-a-case-report-with-a-literature-review
#11
Karim Mohamed-Noriega, Karla Butrón-Valdez, Jeronimo Vazquez-Galvan, Jibran Mohamed-Noriega, Humberto Cavazos-Adame, Jesús Mohamed-Hamsho
PURPOSE: To report the case of a 50-year-old woman with diabetes that presented with corneal melting and perforation 6 weeks after collagen cross-linking (CxL) for keratoconus (KC) and postoperative use of nepafenac eye drops, a nonsteroidal anti-inflammatory drug (NSAID). METHODS: This is a case report of a patient with diabetes, KC and a thin cornea that had undergone left eye corneal CxL at a different hospital followed by postoperative use of nepafenac eye drops for 6 weeks...
January 2016: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/27163618/in-vivo-confocal-microscopy-after-contact-lens-assisted-corneal-collagen-cross-linking-for-thin-keratoconic-corneas
#12
Cosimo Mazzotta, Soosan Jacob, Amar Agarwal, Dhivya Ashok Kumar
PURPOSE: To study in vivo confocal microscopy (IVCM) after contact lens-assisted corneal collagen cross-linking (CACXL) in keratoconic eyes with thin corneas. METHODS: This prospective interventional case series included patients with progressive keratoconus with minimum corneal thickness less than 400 µm after removing epithelium. CACXL was done once functional corneal thickness was confirmed to be 400 µm or greater after applying a riboflavin-soaked, ultraviolet barrier-free contact lens...
May 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27113884/intraoperative-corneal-thickness-change-and-clinical-outcomes-after-corneal-collagen-crosslinking-standard-crosslinking-versus-hypotonic-riboflavin
#13
Elan Rosenblat, Peter S Hersh
PURPOSE: To determine intraoperative changes in corneal thickness and outcomes of corneal collagen crosslinking (CXL) using 2 intraoperative regimens: riboflavin-dextran or hypotonic riboflavin. SETTING: Cornea and refractive surgery practice, Teaneck, New Jersey, USA. DESIGN: Prospective randomized case series. METHODS: Eyes with keratoconus or corneal ectasia were treated. All eyes received preloading with riboflavin 0...
April 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27097560/outcomes-of-corneal-collagen-crosslinking-using-a-customized-epithelial-debridement-technique-in-keratoconic-eyes-with-thin-corneas
#14
Nurullah Cagil, Ozge Sarac, Gamze Dereli Can, Emine Akcay, Mehmet Erol Can
The purpose of the study was to evaluate the outcomes and possible complications of CXL performed with customized epithelial debridement technique to keratoconic corneas with the thinnest pachymetry values less than 400 µm. Nineteen eyes of 19 patients were included. The uncorrected (UCVA) and best corrected visual acuity (BCVA), flattest and steepest keratometric (K) readings, central corneal thickness at the thinnest point (t-CCT), endothelial cell density (ECD) were assessed before and 12 months after CXL...
February 2017: International Ophthalmology
https://www.readbyqxmd.com/read/26655487/comparison-of-results-of-accelerated-corneal-cross-linking-with-hypo-osmolar-riboflavin-solution-performed-on-corneas-thicker-and-thinner-than-400-%C3%AE-m
#15
COMPARATIVE STUDY
Mustafa Koç, Mehmet Murat Uzel, Yaran Koban, Irfan Durukan, Kemal Tekin, Pelin Ylmazbaş
PURPOSE: To evaluate the effect of accelerated corneal cross-linking (CXL) according to corneal thickness in keratoconus. METHODS: Patients undergoing corneal CXL (9 mW/cm(2)) with hypo-osmolar riboflavin solution were included in this study. The patients were divided into 2 groups. Group 1 included patients with corneal thickness below 400 μm (50 eyes from 45 patients), and group 2 included patients with corneal thickness above 400 μm (50 eyes from 47 patients)...
February 2016: Cornea
https://www.readbyqxmd.com/read/26653730/increased-biomechanical-efficacy-of-corneal-cross-linking-in-thin-corneas-due-to-higher-oxygen-availability
#16
COMPARATIVE STUDY
Sabine Kling, Olivier Richoz, Arthur Hammer, David Tabibian, Soosan Jacob, Amar Agarwal, Farhad Hafezi
PURPOSE: To compare the currently available ultraviolet-A (UV-A) corneal cross-linking (CXL) treatment protocols for thin corneas with respect to oxygen, UV fluence, and osmotic pressure. METHODS: Freshly enucleated murine (n = 16) and porcine (n = 16) eyes were used. The dependency on oxygen and the amount of UV absorption were evaluated using different CXL protocols, including standard CXL, contact lens-assisted CXL (caCXL), and CXL after corneal swelling. The CXL protocol was adapted from the treatment parameters of the human cornea to fit the thickness of murine and porcine corneas...
December 2015: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/26650390/three-different-protocols-of-corneal-collagen-crosslinking-in-keratoconus-conventional-accelerated-and-iontophoresis
#17
Nacim Bouheraoua, Lea Jouve, Vincent Borderie, Laurent Laroche
Keratoconus is a bilateral and progressive corneal ectasia. In order to slow down its progression, corneal collagen cross-linking (CXL) has recently been introduced as an efficient treatment option. In biological and chemical sciences, crosslinking refers to new chemical bonds formed between reactive molecules. Hence, the aim of corneal collagen CXL is to synthetically increase the formation of crosslinks between collagen fibrils in the corneal stroma. Despite the fact that the efficiency of the conventional CXL (C-CXL) protocol has already been shown in several clinical studies, it might benefit from improvements in duration of the procedure and removal of corneal epithelium...
November 12, 2015: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/26605368/corneal-collagen-cross-linking-cxl-in-thin-corneas
#18
REVIEW
Xiangjun Chen, Aleksandar Stojanovic, Jon Roger Eidet, Tor Paaske Utheim
Corneal collagen cross-linking (CXL) is a therapeutic procedure aiming at increasing the corneal stiffness in the keratoconus eyes by induction of cross-links within the extracellular matrix. It is achieved by ultraviolet-A (370 nm) irradiation of the cornea after saturation with the photosensitizer riboflavin. In the conventional CXL protocol, a minimum de-epithelialized corneal thickness of 400 μm is recommended to avoid potential irradiation damage to the corneal endothelium. In advanced keratoconus, however, stromal thickness is often lower than 400 μm, which limits the application of CXL in that category...
2015: Eye and Vision (London, England)
https://www.readbyqxmd.com/read/26064737/late-stage-of-corneal-decompensation-caused-by-progressive-keratoconus-can-we-treat-it-and-save-the-cornea
#19
Igor Knezović, Mirna Belovari Višnjić, Hrvoje Raguž
Aim. To report a case of 40-year-old male with progressive bilateral keratoconus who had undergone transepithelial phototherapeutic keratectomy (TE-PTK) and corneal collagen cross-linking (CXL) using hypoosmolar riboflavin solution in a same day procedure. Methods. Eye examination showed that UCDVA on both eyes was 0,01 according to Snellen charts, and slit lamp biomicroscopy showed paracentral diffuse intrastromal corneal haze. Anterior OCT marked stromal hyperreflective zones and localized paracentral thinning of the cornea...
2015: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/25953470/tailored-stromal-expansion-with-a-refractive-lenticule-for-crosslinking-the-ultrathin-cornea
#20
Mahipal S Sachdev, Deepa Gupta, Gitansha Sachdev, Ritika Sachdev
We describe a technique for stromal expansion of thin and ultrathin corneas in keratoconus patients that uses refractive stromal lenticules of patients having small-incision lenticule extraction for myopic correction. The stromal lenticule is placed and spread over the host cornea following epithelial debridement so the thickest area of the 6.2 mm diameter lenticule corresponds to the thinnest area of the cone. The remaining collagen crosslinking (CXL) procedure is carried out in a routine manner. We believe tailored stromal expansion is a safe and effective technique for performing CXL in patients with thin corneas...
May 2015: Journal of Cataract and Refractive Surgery
keyword
keyword
36430
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"