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Wound dressings

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https://www.readbyqxmd.com/read/29451778/rapid-forming-and-self-healing-agarose-based-hydrogels-for-tissue-adhesives-and-potential-wound-dressings
#1
Zhuo Zhang, Xiaolin Wang, Yitong Wang, Jingcheng Hao
To meet the progressive requirements of advanced engineering materials with superior physicochemical performances, self-healing and injectable hydrogels (AD hydrogels) based on agarose with pH-response were prepared through dynamic covalent Schiff-base linkages by simply mixing nontoxic agarose-ethylenediamine conjugate (AG-NH2) and dialdehyde-functionalized polyethylene glycol (DF-PEG) solutions. The self-healing and injectable capabilities of the hydrogels without any external stimulus are ascribed to dynamic covalent Schiff-base linkages between the aldehyde groups of DF-PEG and amine groups on AG-NH2 backbone...
February 16, 2018: Biomacromolecules
https://www.readbyqxmd.com/read/29451714/development-of-regenerative-and-flexible-fibroin-based-wound-dressings
#2
Angelica Panico, Federica Paladini, Mauro Pollini
Skin injuries represent a health problem with consequences in terms of morbidity, disability and life quality. Numerous strategies have been developed for the treatment of wounds, including skin substitutes, biomembranes, scaffolds, and smart dressings. The excellent properties of fibroin can be exploited for the development of advanced wound dressing biomaterials, aiming at promoting the wound healing process. In this work, silk fibroin films modified through the addition of glucose were developed to enhance flexibility of medical device without affecting the biocompatibility, to promote wound healing and to improve the patient well-being...
February 16, 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29447972/novel-asymmetric-chitosan-pvp-nanocellulose-wound-dressing-in-vitro-and-in-vivo-evaluation
#3
R Poonguzhali, S Khaleel Basha, V Sugantha Kumari
The present study was to develop a novel chitosan based symmetric and asymmetric bionanocomposite for potential wound dressing application. Chitosan (C)/Poly (vinyl pyrrolidone) (P)/nanocellulose (NC) membrane were fabricated by salt leaching method with the addition of 3% and 5% wt of nanocellulose. To obtain asymmetric material one side of the membrane was coated by stearic acid (S) which could form hydrophobic surface and another side acts as a hydrophilic surface. Nanocellulose of size 2-10 nm was synthesized and characterized by TEM analysis...
February 12, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29446015/synthetic-polymeric-biomaterials-for-wound-healing-a-review
#4
Mariam Mir, Murtaza Najabat Ali, Afifa Barakullah, Ayesha Gulzar, Munam Arshad, Shizza Fatima, Maliha Asad
Wounds are of a variety of types and each category has its own distinctive healing requirements. This realization has spurred the development of a myriad of wound dressings, each with specific characteristics. It is unrealistic to expect a singular dressing to embrace all characteristics that would fulfill generic needs for wound healing. However, each dressing may approach the ideal requirements by deviating from the 'one size fits all approach', if it conforms strictly to the specifications of the wound and the patient...
February 14, 2018: Progress in Biomaterials
https://www.readbyqxmd.com/read/29445718/designing-and-developing-automatic-trolley-for-washing-and-dressing-the-wounds
#5
M S Golvardi Yazdi, M Naderizadeh, R Afzalipour, H A Abedi, M Radmehr, R Golvardi Yazdi, Sh Salari Pashaghi
Introduction: Many items are needed for dressing including sterile dressing set, antiseptic and washing solutions, leucoplast tape, waste bin for infectious garbage, waste bin for noninfectious garbage, safe disposal trash for sharp cutting instruments, bedpan and sometimes drugs. All the items are laid out on a simple wheeled trolley. The multiplicity of items together with problems in placing tools on trolley, forgetting some items, disturbing sterile condition, falling and damaging equipment and the need for at least two people for each procedure, all are the reasons to design and develop Automatic Trolley for Washing and Dressing the Wounds...
December 2017: Journal of Biomedical Physics & Engineering
https://www.readbyqxmd.com/read/29444705/health-economic-evaluation-of-moist-wound-care-in-chronic-cutaneous-leishmaniasis-ulcers-in-afghanistan
#6
Hans-Christian Stahl, Faridullah Ahmadi, Sami Mohammad Nahzat, Heng-Jin Dong, Kurt-Wilhelm Stahl, Rainer Sauerborn
BACKGROUND: The present health economic evaluation in Afghanistan aims to support public health decision makers and health care managers to allocate resources efficiently to appropriate treatments for cutaneous leishmaniasis (CL) elicited by Leishmania tropica or Leishmania major. METHODS: A decision tree was used to analyse the cost and the effectiveness of two wound care regimens versus intra-lesional antimony in CL patients in Afghanistan. Costs were collected from a societal perspective...
February 14, 2018: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29443786/improved-vacuum-sealing-drainage-for-treatment-of-surgical-site-infection-following-posterior-spinal-internal-fixation-a-case-report
#7
Hengyan Zhang, Qiyi Li
RATIONALE: Surgical site infection (SSI) following spine surgeries involving internal fixation often require removing the instrument; however, this can cause spinal instability. Previous reports have demonstrated the usefulness of vacuum sealing drainage (VSD) therapy, but the cases require wound opening, aseptic condition to replace the VSD device, and a secondary operation to close the wound. Thus, to improve the VSD treatment and develop a maneuverable procedure, make sense in spine surgery...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29442969/development-of-antibacterial-composite-electrospun-chitosan-coated-polypropylene-materials
#8
Melike Gozutok, Ahmet Ozan Basar, Hilal Turkoglu Sasmazel
In this study, a natural antibacterial substance chitosan was coated with/without potassium sorbate (KS) (0.8% (w/w) of KS, 8% (w/v) chitosan) onto the polypropylene (PP) film by using electrospinning technique to obtain novel antibacterial composite materials for various applications such as wound dressing, tissue engineering, drug delivery and food packaging. Atmospheric pressure plasma surface treatment was applied onto polypropylene films in order to increase its wettability thus enhancing the adhesion capacity of the films and the optimum CA value was determined as 42...
April 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29442910/antibacterial-performance-of-pcl-chitosan-core-shell-scaffolds
#9
Ozan Ozkan, Hilal Turkoglu Sasmazel
In this study, antibacterial performance of the coaxially electrospun Poly-ε-caprolactone (PCL)-chitosan core-shell scaffolds developed, optimized and identified physically and chemically in our previous study, were evaluated for the suitability in wound healing applications. The aim of utilizing a core-shell fibrous scaffold with PCL as core and chitosan as shell was to combine natural biocompatibility, biodegradability and antibacterial properties of chitosan with mechanical properties and resistance to enzymatic degradation of PCL...
April 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29440808/intranasal-ketamine-for-the-management-of-incidental-pain-during-wound-dressing-in-cancer-patients-a-pilot-study
#10
Nivedita Page, Vivek Nirabhawane
Introduction: Cancer wounds need regular dressing; else they develop infection, foul odor, and in extreme cases, maggots. Patients resist dressing due to the severe incidental pain during dressing. Intranasal ketamine was tried as an analgesic to reduce this incidental pain. Materials and Methods: Twenty patients with wounds requiring regular dressing were selected; these patients had a basal pain score of 4/10 and incidental pain score of 7/10 during four consecutive dressings...
January 2018: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/29440678/development-of-a-bacterial-cellulose-based-hydrogel-cell-carrier-containing-keratinocytes-and-fibroblasts-for-full-thickness-wound-healing
#11
Evelyn Yun Xi Loh, Najwa Mohamad, Mh Busra Fauzi, Min Hwei Ng, Shiow Fern Ng, Mohd Cairul Iqbal Mohd Amin
Bacterial cellulose (BC)/acrylic acid (AA) hydrogel has successfully been investigated as a wound dressing for partial-thickness burn wound. It is also a promising biomaterial cell carrier because it bears some resemblance to the natural soft tissue. This study assessed its ability to deliver human epidermal keratinocytes (EK) and dermal fibroblasts (DF) for the treatment of full-thickness skin lesions. In vitro studies demonstrated that BC/AA hydrogel had excellent cell attachment, maintained cell viability with limited migration, and allowed cell transfer...
February 13, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29440165/correction-bluebelle-study-phase-a-a-mixed-methods-feasibility-study-to-inform-an-rct-of-surgical-wound-dressing-strategies
#12
(no author information available yet)
No abstract text is available yet for this article.
February 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29438144/long-term-scar-quality-after-treatment-of-standardized-partial-thickness-skin-graft-donor-sites
#13
Alexandra Schulz, Irene Rothermund, Rolf Lefering, Paul Christian Fuchs, Jennifer Schiefer
BACKGROUND: The long-term aesthetic appearance of scars is of great importance to patients. Biobrane (Smith and Nephew, Fort Worth, Texas), a biosynthetic skin dressing, is a successfully established dressing for the treatment of superficial wounds. A new silk barrier dressing (Dressilk; Prevor, Moulin de Verville, France) has also shown good results in wound healing. This study evaluated the long-term scar quality of superficial wounds treated with these dressings. METHODS: From February 2012 to May 2013, 11 patients with burns in need of skin grafting received donor site treatment...
March 2018: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/29436991/antibacterial-strategies-for-wound-dressing-preventing-infection-and-stimulating-healing
#14
Zhengwen Li, Menno Knetsch
Wound management is an important and increasing global issue. Infection of a wound can cause a delay in wound healing and pain, but also more serious complications like tissue necrosis or even sepsis, which can lead to loss of tissue, limbs or life. Antibacterial agents have been introduced into wound infection care. In this review, we provide an insight into the current antibacterial strategies of wound dressings, including wound infection process, antibacterial agents, and controlled drug release systems...
February 13, 2018: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29436708/nursing-wound-care-practices-in-haiti-facilitators-and-barriers-to-quality-care
#15
B A Timmins, C Thomas Riché, M W Saint-Jean, J Tuck, L Merry
AIM: To describe the facilitators and barriers for nurses to perform quality wound care in three surgical wards of a hospital in Port-au-Prince, Haiti. BACKGROUND: Up to a quarter of patients in low- and middle-income countries may acquire at least one infection while hospitalized. There is a paucity of research investigating nursing wound care practices in low- and middle-income countries regarding the prevention of hospital-acquired infections. METHODS: The design was qualitative descriptive...
February 13, 2018: International Nursing Review
https://www.readbyqxmd.com/read/29436028/biomedical-applications-of-recombinant-silk-based-materials
#16
REVIEW
Tamara Bernadette Aigner, Elise DeSimone, Thomas Scheibel
Silk is mostly known as a luxurious textile, which originates from silkworms first cultivated in China. A deeper look into the variety of silk reveals that it can be used for much more, in nature and by humanity. For medical purposes, natural silks were recognized early as a potential biomaterial for surgical threads or wound dressings; however, as biomedical engineering advances, the demand for high-performance, naturally derived biomaterials becomes more pressing and stringent. A common problem of natural materials is their large batch-to-batch variation, the quantity available, their potentially high immunogenicity, and their fast biodegradation...
February 13, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29434717/efficacy-of-thermosensitive-chitosan-%C3%AE-glycerophosphate-hydrogel-loaded-with-%C3%AE-cyclodextrin-curcumin-for-the-treatment-of-cutaneous-wound-infection-in-rats
#17
Yong Zhao, Jia-Guo Liu, Wei-Min Chen, Ai-Xi Yu
Wound infection has been a persistent problem that is common and costly. Thermosensitive hydrogel has been demonstrated to be a suitable dressing candidate due to its high moldability, easy administration and ability to maintain a moist topical environment at the wound bed. In the present study, a novel thermosensitive hydrogel was successfully prepared and characterized to have a porous inner structure and a sustained curcumin-releasing profile. The wound healing ability of the hydrogel was investigated in a wound infection model in rats...
February 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29432820/qpcr-detection-of-lichtheimia-species-in-bandages-associated-with-cutaneous-mucormycosis-in-burn-patients
#18
E Fréalle, S Rocchi, M Bacus, H Bachelet, L Pasquesoone, B Tavernier, D Mathieu, L Millon, M Jeanne
BACKGROUND: Cutaneous mucormycoses, mainly due to Lichtheimia (Absidia), have occurred on several occasions in the Burn Unit of the University Hospital of Lille, France. AIM: To investigate the potential vector role of non-sterile bandages used to hold in place sterile gauze used for wound dressing. METHODS: Mycological analysis by conventional culture, Mucorales qPCR, and Lichtheimia species-specific qPCR were performed on 8 crepe and 6 elasticized bandages that were sampled on two independent soccasions in March 2014 and July 2016...
February 9, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29430495/a-comparison-of-the-postoperative-complications-between-two-drainage-methods-after-total-knee-arthroplasty
#19
Fardin Mirzatolooei, Ali Tabrizi, Maryamsadat Mokaram Gargari
Background: The role of wound drainage after total knee arthroplasty is still considered controversial as although closed drainage systems have been believed to be effective in decreasing the post-operative complications, they could also facilitate the bleeding and increase the rate of transfusion and infection. We have conducted the current study to compare the outcomes superficial subcutaneous, one deep, and two deep drain techniques after total knee arthroplasty. Methods: Between 2014 and 2015 sixty consecutive patients were prospectively selected and underwent primary total knee arthroplasty...
January 2018: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/29428812/development-of-reduced-graphene-oxide-rgo-isabgol-nanocomposite-dressings-for-enhanced-vascularization-and-accelerated-wound-healing-in-normal-and-diabetic-rats
#20
Ponrasu Thangavel, Ramya Kannan, Balaji Ramachandran, Ganeshkumar Moorthy, Lonchin Suguna, Vignesh Muthuvijayan
Treatment of chronic non-healing wounds in diabetes is still a major clinical challenge. Here, we have developed reduced graphene oxide (rGO) loaded isabgol nanocomposite scaffolds (Isab + rGO) to treat normal and diabetic wounds. rGO was synthesized by rapid reduction of graphene oxide (GO) under focused solar radiation. Then, rGO was uniformly dispersed into isabgol solution to prepare Isab + rGO nanocomposite scaffolds. These scaffolds were characterized using various physiochemical techniques. Isab + rGO nanocomposite scaffolds showed suitable cell viability, proliferation, and attachment...
February 2, 2018: Journal of Colloid and Interface Science
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