keyword
MENU ▼
Read by QxMD icon Read
search

Vasoplegic syndrome

keyword
https://www.readbyqxmd.com/read/27749291/hydroxocobalamin-for-vasoplegic-syndrome-in-liver-transplantation-restoration-of-blood-pressure-without-vasospasm
#1
Harvey J Woehlck, Brent T Boettcher, Kathryn K Lauer, David C Cronin, Johnny C Hong, Michael A Zimmerman, Joohyun Kim, Motaz Selim
Systemic vasoplegia is common in patients undergoing liver transplantation. In this report, we present a case in which treatment with conventional vasopressors caused peripheral arterial spasm, rendering arterial blood pressure monitoring impossible. Administration of methylene blue resolved the vasospasm; however, concern for toxic dose requirements limited its use. Hydroxocobalamin administration resolved the vasospasm and increased blood pressure without the potential adverse effects seen with methylene blue...
October 5, 2016: A & A Case Reports
https://www.readbyqxmd.com/read/27561907/use-of-methylene-blue-to-treat-hypovolemic-shock-followed-by-ischemia-reperfusion-injury-in-the-postoperative-orthotopic-liver-transplant-patient-a-case-report
#2
Kelvin Henrique Vilalva, Fabrícia Teixeira Mumic, Marina Rodrigues Garcia Silveira, Enio David Mente, Paulo Roberto Barbosa Evora, Orlando Castro E Silva
A 57-year-old female patient received elective liver transplant due to nonalcoholic steatohepatitis complicated by hepatocellular carcinoma. Her preoperative Model for End-Stage Liver Disease score was 11. The total transplant ischemic time was 10 hours and 35 minutes, and the warm ischemic time was 35 minutes. Even with aggressive fluid overload and use of high concentrations of vasoactive amines, the patient developed possible primary graft dysfunction with poor response to fluids and vasopressor support, suggesting vasoplegic syndrome...
August 24, 2016: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/27163423/cardiopulmonary-bypass-increases-the-risk-of-vasoplegic-syndrome-after-coronary-artery-bypass-grafting-in-patients-with-dialysis-dependent-chronic-renal-failure
#3
Nelson Américo Hossne Junior, Matheus Miranda, Marcus Rodrigo Monteiro, João Nelson Rodrigues Branco, Guilherme Flora Vargas, José Osmar Medina de Abreu Pestana, Walter José Gomes
OBJECTIVE: Coronary artery bypass grafting is currently the best treatment for dialysis patients with multivessel coronary artery involvement. Vasoplegic syndrome of inflammatory etiology constitutes an important postoperative complication, with highly negative impact on prognosis. Considering that these patients have an intrinsic inflammatory response exacerbation, our goal was to evaluate the incidence and mortality of vasoplegic syndrome after myocardial revascularization in this group...
July 2015: Revista Brasileira de Cirurgia Cardiovascular
https://www.readbyqxmd.com/read/27161180/use-of-oral-droxidopa-to-improve-arterial-pressure-and-reduce-vasoactive-drug-requirements-during-persistent-vasoplegic-syndrome-after-cardiac-transplantation
#4
M Tracy Zundel, Brent T Boettcher, Joel T Feih, Nunzio Gaglianello, Paul S Pagel
No abstract text is available yet for this article.
December 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/27142905/key-points-for-curbing-cardiopulmonary-bypass-inflammation
#5
Paulo Roberto Barbosa Evora, Camila Bottura, Livia Arcêncio, Agnes Afrodite Sumarelli Albuquerque, Patrícia Martinez Évora, Alfredo José Rodrigues
PURPOSE: Cardiopulmonary bypass (CPB) procedures are thought to activate systemic inflammatory reaction syndrome (SIRS). Strategies to curb systemic inflammation have been previously described. However, none of them is adequate, since "curbing" the extent of the inflammatory response requires a multimodal approach. The aim of the present mini-review is to discuss the main key points about the main principles in cardiopulmonary bypass curbing inflammation. METHODS: No systematic literature search (MEDLINE) and extracted data from the accumulated experience of the authors...
2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27004393/-vasoplegic-syndrome-after-aortic-valve-replacement
#6
Kazuto Miyata, Sayaka Shigematsu
We report a case of vasoplegic syndrome (VS) after aortic valve replacement in a 65 year old male with aortic stenosis. The patient developed hypotension after separation from cardiopulmonary bypass (CPB). Transesophageal echocardiography revealed well-maintained cardiac function and normal prosthetic valve function. However, his cardiac index was 3.0 l x min(-1) x m(-2) and systemic vascular resistance index (SVRI) was 1100 dynes x sec(-1) x cm(-5) x m(-2). Diagnosing VS, norepinephrine administration was commenced...
January 2016: Masui. the Japanese Journal of Anesthesiology
https://www.readbyqxmd.com/read/26934199/serotonin-syndrome-following-methylene-blue-administration-for-vasoplegic-syndrome
#7
Laura Hencken, Long To, Nancy Ly, Jeffrey A Morgan
Methylene blue (MB) has been used for additional blood pressure support in patients who develop severe, refractory vasoplegia; however, MB can induce serotonin syndrome, especially when used in conjunction with other serotonergic agents. We describe a case of serotonin syndrome in a patient who received MB for vasoplegic syndrome after left ventricular assist device implantation and discuss its presentation and management.
April 2016: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/26475799/the-effect-of-inotropes-and-vasopressors-on-mortality-a-meta-analysis-of-randomized-clinical-trials
#8
A Belletti, M L Castro, S Silvetti, T Greco, G Biondi-Zoccai, L Pasin, A Zangrillo, G Landoni
BACKGROUND: Inotropes and vasopressors are frequently administered to critically ill patients in order to improve haemodynamic function and restore adequate organ perfusion. However, some studies have suggested a possible association between inotrope administration and increased mortality. We therefore performed a meta-analysis of randomized trials published in the last 20 yr to investigate the effect of these drugs on mortality. METHODS: BioMedCentral, PubMed, Embase and the Cochrane Central Register were searched (all updated April 8th, 2015)...
November 2015: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/26347436/a-novel-use-of-methylene-blue-in-the-pediatric-icu
#9
Chrystal Rutledge, Brian Brown, Kimberley Benner, Priya Prabhakaran, Leslie Hayes
Methylene blue (MB) is a medication commonly used to treat methemoglobinemia, reducing methemoglobin to hemoglobin. A novel use of MB, as detailed here, is in the treatment of refractory hypotension. A number of reports have detailed use of MB for this purpose in adults, but few data in pediatrics. A 22-month-old girl with Noonan syndrome, biventricular hypertrophic cardiomyopathy, and chronic positive pressure ventilation developed shock with tachycardia, hypotension, and fever after 3 days of diarrhea. She was critically ill, with warm extremities, bounding pulses, and brisk capillary refill...
October 2015: Pediatrics
https://www.readbyqxmd.com/read/26136914/methylene-blue-treatment-for-cytokine-release-syndrome-associated-vasoplegia-following-a-renal-transplant-with-ratg-infusion-a-case-report-and-literature-review
#10
John T Denny, Andrew T Burr, Fred Balzer, James T Tse, Julia E Denny, Darrick Chyu
Rabbit anti-thymocyte globulin (rATG) is an infusion of polyclonal rabbit-derived antibodies against human thymocyte markers, which can be used to prevent and treat acute rejection following organ transplantation. However, the product monograph issued by the manufacturer (Sanofi Canada) reports that serious immune-mediated reactions have been observed following the use of rATG, consisting of anaphylaxis or severe cytokine release syndrome (CRS), which is a form of vasoplegic syndrome (VS), in which distributive shock occurs refractory to norepinephrine (NE) and vasopressin (VP)...
May 2015: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/25859872/twenty-years-of-vasoplegic-syndrome-treatment-in-heart-surgery-methylene-blue-revised
#11
REVIEW
Paulo Roberto Barbosa Evora, Lafaiete Alves Junior, Cesar Augusto Ferreira, Antônio Carlos Menardi, Solange Bassetto, Alfredo José Rodrigues, Adilson Scorzoni Filho, Walter Vilella de Andrade Vicente
OBJECTIVE: This study was conducted to reassess the concepts established over the past 20 years, in particular in the last 5 years, about the use of methylene blue in the treatment of vasoplegic syndrome in cardiac surgery. METHODS: A wide literature review was carried out using the data extracted from: MEDLINE, SCOPUS and ISI WEB OF SCIENCE. RESULTS: The reassessed and reaffirmed concepts were 1) MB is safe in the recommended doses (the lethal dose is 40 mg/kg); 2) MB does not cause endothelial dysfunction; 3) The MB effect appears in cases of NO up-regulation; 4) MB is not a vasoconstrictor, by blocking the cGMP pathway it releases the cAMP pathway, facilitating the norepinephrine vasoconstrictor effect; 5) The most used dosage is 2 mg/kg as IV bolus, followed by the same continuous infusion because plasma concentrations sharply decrease in the first 40 minutes; and 6) There is a possible "window of opportunity" for MB's effectiveness...
January 2015: Revista Brasileira de Cirurgia Cardiovascular
https://www.readbyqxmd.com/read/25611876/serotonin-syndrome-after-cardiopulmonary-bypass-a-case-demonstrating-the-interaction-between-methylene-blue-and-selective-serotonin-reuptake-inhibitors
#12
Engy R Hanna, Jeffrey A Clark
Methylene blue, a drug used to treat vasoplegia and methemoglobinemia, also inhibits monoamine oxidase-A. When given in combination with serotonergic medications, methylene blue can lead to serotonin excess syndrome. Given the widespread use of serotonergic medication to treat depression, anesthesia providers should be aware of this potentially lethal interaction. Patients undergoing cardiopulmonary bypass for cardiac surgery are a specific population at risk for postbypass vasoplegic shock. The use of methylene blue to treat vasoplegia in this group of patients should be weighed in light of their current medications and potential drug interactions...
May 1, 2014: A & A Case Reports
https://www.readbyqxmd.com/read/25013651/very-high-dose-epinephrine-for-the-treatment-of-vasoplegic-syndrome-during-liver-transplantation
#13
M B Khosravi, S Milani, S Ghaffaripour, A Sahmeddini, M H Eghbal, S A Malek-Hosseini
A 55-year-old man with hepatitis B and hepatocellular carcinoma was treated with liver transplantation without veno-venous bypass. During the procedure his arterial blood pressure remained at 55/30 mm Hg and did not respond to increasing doses of norepinephrine. Vasoplegia was managed aggressively with the intravenous infusion of high doses of epinephrine.
2013: International Journal of Organ Transplantation Medicine
https://www.readbyqxmd.com/read/24794391/methylene-blue-modulates-adhesion-molecule-expression-on-microvascular-endothelial-cells
#14
Isabella Werner, Fengwei Guo, Ulrich A Stock, Michèle Lupinski, Patrick Meybohm, Anton Moritz, Andres Beiras-Fernandez
OBJECTIVE AND DESIGN: As methylene blue (MB) has been recently proposed to preserve blood pressure in case of vasoplegic syndrome and shock, an entity directly related to systemic inflammation, we aimed to elucidate the effect of MB on the expression of adhesion-molecules in endothelial-cells. MATERIALS AND TREATMENT: Human microvascular endothelial-cells (HuMEC-1) were treated with 10, 30 or 60 µM MB for 30 min and 2 h each. Additionally, the treated HuMEC-1 were co-cultured with either human peripheral blood mononuclear cells (PBMCs) or Jurkat cells (human T-lymphocytes) for 2 h...
August 2014: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]
https://www.readbyqxmd.com/read/24792267/the-use-of-high-dose-hydroxocobalamin-for-vasoplegic-syndrome
#15
Joseph D Roderique, Kofi VanDyck, Brita Holman, Daniel Tang, Betty Chui, Bruce D Spiess
We describe a case of hypotension on cardiopulmonary bypass for coronary artery bypass grafting, double valve repairs, and patent foramen ovale closure. The patient experienced vasoplegic syndrome while on cardiopulmonary bypass. He was treated with high-dose hydroxocobalamin (vitamin B12). His blood pressure responded rapidly, obviating any further vasopressor requirements.
May 2014: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/24368966/moderate-and-deep-hypothermia-produces-hyporesposiveness-to-phenylephrine-in-isolated-rat-aorta
#16
Jun Woo Cho, Chul Ho Lee, Jae Seok Jang, Oh Choon Kwon, Woon Seok Roh, Jung Eun Kim
BACKGROUND: Moderate and severe hypothermia with cardiopulmonary bypass during aortic surgery can cause some complications such as endothelial cell dysfunction or coagulation disorders. This study found out the difference of vascular reactivity by phenylephrine in moderate and severe hypothermia. METHODS: Preserved aortic endothelium by excised rat thoracic aorta was sectioned, and then down the temperature rapidly to 25℃ by 15 minutes at 38℃ and then the vascular tension was measured...
December 2013: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/23956362/ecomment-potential-therapeutic-agents-in-vasoplegic-syndrome-after-cardiac-surgery
#17
COMMENT
Senol Yavuz, Faruk Toktas, Suleyman Surer, Cuneyt Eris
No abstract text is available yet for this article.
September 2013: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/23804482/the-role-of-methylene-blue-in-the-pediatric-patient-with-vasoplegic-syndrome
#18
Tarun Bhalla, Amod Sawardekar, Hyde Russell, Joseph D Tobias
Patients with vasoplegic syndrome (VPS) in the post-cardiopulmonary bypass setting usually require escalating vasopressor support. The utilization of methylene blue (MB) in the treatment of VPS in the adult population has been well described. We present a 5-year-old girl who developed vasodilatory shock due to VPS that was resistant to escalating doses of adrenergic agonists following cardiac transplantation. After receiving 1 mg/kg of MB, there was a significant improvement in the patient's mean arterial pressure which allowed for progressive weaning of the vasopressor support...
October 1, 2011: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/23736659/pre-existing-endothelial-cell-activation-predicts-vasoplegia-after-mitral-valve-surgery
#19
Kirsten A Kortekaas, Jan H N Lindeman, Marlies E J Reinders, Meindert Palmen, Robert J M Klautz, Philip G de Groot, Mark Roest
OBJECTIVES: Post-cardiac surgery vasoplegia is a common complication of cardiac surgery, characterized by profound loss of systemic vascular resistance. This results in severe hypotension, high cardiac output and metabolic acidosis reflecting inadequate tissue perfusion. The pathophysiological mechanisms underlying this syndrome remain unknown. We hypothesized that this vasoplegia reflects endothelial dysfunction, either as pre-existing condition or as a consequence of the surgical procedure...
September 2013: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/22848976/methylene-blue-to-treat-vasoplegia-due-to-a-severe-protamine-reaction-a-case-report
#20
Dina L Lutjen, Karri L Arndt
Protamine sulfate is used during coronary artery bypass graft surgery to reverse the anticoagulating effects of heparin. Vasoplegic syndrome is a state of endothelial dysregulation that produces profound vasodilatation that is refractory to vasopressors. This syndrome leads to systemic hypoperfusion and may progress to death. Up to 27% of patients after cardiac bypass may experience vasoplegia. Symptoms of vasoplegia may also be present in many different clinical settings. This case report describes a 57-year-old woman who after cardiac bypass experienced a severe protamine reaction with profound hypotension, which was unresponsive to volume resuscitation and vasopressor therapy...
June 2012: AANA Journal
keyword
keyword
36408
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"