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Pulp revascularization

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https://www.readbyqxmd.com/read/28612428/outcomes-and-prognostic-factors-that-influence-the-success-of-tooth-autotransplantation-in-children-and-adolescents
#1
Vasiliki Kafourou, Huei Jinn Tong, Peter Day, Nadine Houghton, R James Spencer, Monty Duggal
BACKGROUND/AIM: Tooth autotransplantation has been advocated for replacement of missing teeth, or teeth that are unsuitable for restoration. The aim of this study was to investigate the outcomes and prognostic factors that influenced the success of tooth transplantation in a paediatric population. MATERIALS AND METHODS: Data was extracted from the records of 75 patients (89 teeth). Demographic and prognostic factors were recorded and analyzed for the clinical and radiographic outcomes for periodontal ligament (PDL) and pulp healing of transplanted teeth...
June 14, 2017: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://www.readbyqxmd.com/read/28567136/pulp-revascularization-a-literature-review
#2
REVIEW
Pollyana Rodrigues de Souza Araújo, Luciano Barreto Silva, Alexandrino Pereira Dos Santos Neto, José Alcides Almeida de Arruda, Pâmella Recco Álvares, Ana Paula Veras Sobral, Severino Alves Júnior, Jair Carneiro Leão, Rodivan Braz da Silva, Gerhilde Callou Sampaio
Reestablishing blood flow and allowing the continuation of root development are some of the objectives of pulp revascularization. This procedure is currently indicated for teeth with incomplete root formation as an alternative to the traditional treatment of apecification, which consists of inserting calcium hydroxide paste into the root canal for a determined time period in order to induce the formation of a calcified barrier. Although it is considered as the most classically employed therapy, the permanence of the paste for long time periods may lead to the weakening of the root due to hygroscopic properties, as well as proteolytic activities of calcium hydroxide...
2017: Open Dentistry Journal
https://www.readbyqxmd.com/read/28527847/self-repaired-process-of-a-traumatized-maxillary-central-incisor-with-pulp-infarct-after-horizontal-root-fracture-monitored-by-laser-doppler-flowmetry-combined-with-tissue-oxygen-monitor
#3
Qian Liao, Wenjun Ye, Junli Yue, Xiaoxi Zhao, Ling Zhang, Lan Zhang, Dingming Huang, Qinghua Zheng
Achieving a precise diagnosis of the pulp status of traumatized teeth is difficult. The time to interfere through endodontic treatment for these teeth is greatly dependent on the doctor's experience. A 24-year-old male patient suffered a traumatic injury to tooth #9 that resulted in an apical root horizontal fracture 3 days before he came to the hospital. The injured tooth showed no response to pulp sensitivity testing at the first visit and was discolored 1 week later. Tooth #9 was immobilized to its adjacent teeth for 4 weeks by a composite splint...
May 17, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28511779/an-evidence-based-review-of-the-efficacy-of-treatment-approaches-for-immature-permanent-teeth-with-pulp-necrosis
#4
REVIEW
Bill Kahler, Giampiero Rossi-Fedele, Nadia Chugal, Louis M Lin
INTRODUCTION: Two fundamental assumptions for teeth treated with regenerative endodontic procedures (REPs) are (1) that the clinical outcome is comparable with the traditional techniques of calcium hydroxide apexification and mineral trioxide aggregate apical barrier techniques and (2) that REPs will result in further root maturation. METHODS: A systematic review of the electronic databases (Scopus, PubMed, and Web of Science) involved a search for studies that used quantitative assessments of root maturation...
May 13, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28456015/do-autotransplanted-teeth-require-elective-root-canal-therapy-a-long-term-follow-up-case-series
#5
Linda Murtadha, Jerry Kwok
PURPOSE: To determine the long-term survival and outcomes of 252 autotransplanted teeth with a novel root canal therapy (RCT) and follow-up protocol and to establish whether elective RCT after autotransplantation is routinely required for teeth with complete root formation. PATIENTS AND METHODS: A retrospective analysis of 209 patients 10 to 58 years old, with a total of 252 autotransplants was carried out with a minimum observational period of 1 year and a maximum period of 29 years...
April 5, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28416306/histologic-findings-of-a-human-immature-revascularized-regenerated-tooth-with-symptomatic-irreversible-pulpitis
#6
Chufang Peng, Yuming Zhao, Wenjun Wang, Yuan Yang, Man Qin, Lihong Ge
INTRODUCTION: Pulp revascularization/regeneration in immature permanent teeth with necrotic pulp and/or apical periodontitis is an effective approach for inducing root maturation. Previous histologic studies showed cementoid/osteoid tissue and/or periodontal ligament-like tissue formed within the root canals. This case report describes the histologic findings of a human symptomatic irreversible pulpitis immature permanent tooth with most of the pulp removed after a revascularization/regeneration procedure...
April 14, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28415948/use-of-platelet-rich-plasma-for-regeneration-in-non-vital-immature-permanent-teeth-clinical-and-cone-beam-computed-tomography-evaluation
#7
Adel Alagl, Sumit Bedi, Khalid Hassan, Jehan AlHumaid
Objective This study was performed to assess the clinical and radiological outcomes of a revascularization procedure in immature teeth with apical periodontitis using platelet-rich plasma (PRP). The PRP protocol and conventional revascularization protocol, which used a blood clot as the scaffold, were compared. Methods Thirty non-vital immature permanent teeth were randomly categorized into two groups. After disinfecting the root canal space with triple antibiotic paste (1:1:1 ciprofloxacin, metronidazole, and cefaclor), a tissue scaffold was created using either PRP or a blood clot (control) and covered with white mineral trioxide aggregate...
April 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28372291/current-challenges-in-human-tooth-revitalization
#8
Maxime Ducret, Hugo Fabre, Alexis Celle, Frédéric Mallein-Gerin, Emeline Perrier-Groult, Brigitte Alliot-Licht, Jean-Christophe Farges
Tooth vitality and health are related to the presence of a living connective tissue, the dental pulp (DP), in the center of the dental organ. The DP contains the tooth immune defence system that is activated against invading oral cariogenic bacteria during the caries process and the tissue repair/regeneration machinery involved following microorganisms' eradication. However, penetration of oral bacteria into the DP often leads to complete tissue destruction and colonization of the endodontic space by microorganisms...
2017: Bio-medical Materials and Engineering
https://www.readbyqxmd.com/read/28342218/histological-assessment-of-regenerative-endodontic-treatment-in-animal-studies-with-different-scaffolds-a-systematic-review
#9
REVIEW
Milad Altaii, Lindsay Richards, Giampiero Rossi-Fedele
BACKGROUND/AIM: The concept of regenerative endodontic procedures remains controversial. The aim of this study was to evaluate the histology of the tissues formed in immature animal teeth with necrotic and infected pulps after attempted endodontic regeneration procedures using different scaffolds. DESIGN: A systematic electronic literature search was performed in PubMed, Web of Science, Scopus, EMBASE, DOSS, and Cochrane Library databases. The terms used were a combination of the following: "immature permanent necrotic tooth or teeth" or "open apex or apices" and "regeneration or revitalization or revascularization" and "histology...
March 24, 2017: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://www.readbyqxmd.com/read/28294199/management-of-an-immature-partially-necrotic-permanent-molar-by-pulp-revascularization-%C3%A2-two-year-follow-up
#10
Julian Schmoeckel, Mhd Said Mourad, Christian H Splieth, Ruth M Santamaria
Root canal treatment of immature teeth is considered a great challenge for both the dentist and the patient. The thinness of the root canals walls and the lack of an apical barrier leads to unpredictable treatment results. Revascularization is a novel promising treatment option in the field of regenerative endodontics for management of immature necrotic permanent teeth. This case presents a successful treatment of an 8-year-old patient with a partially necrotic, immature permanent mandibular right first molar pulp by revascularization...
March 14, 2017: Quintessence International
https://www.readbyqxmd.com/read/28293394/evaluation-of-the-expression-of-viii-factor-and-vegf-in-the-regeneration-of-non-vital-teeth-in-dogs-using-propolis
#11
Mina Zarei, Amir Hossein Jafarian, Azadeh Harandi, Maryam Javidi, Maryam Gharechahi
OBJECTIVES: The purpose of the present study was the immunohistochemical evaluation of VEGF and VII factors in dog's teeth pulp revascularized with MTA and propolis. MATERIALS AND METHODS: 144 mature and immature two rooted dog's premolar canals were selected. Pulp necrosis and infection were established after 2 weeks and the disinfection of the canals was done with copious NaOCl irrigation and triantibiotic mixture (ciprofloxacin, metronidazole, and minocycline) for 3 weeks...
February 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28194367/retreatment-of-failed-regenerative-endodontic-of-orthodontically-treated-immature-permanent-maxillary-central-incisor-a-case-report
#12
Musaed Fahad Al-Tammami, Saad A Al-Nazhan
A revascularization procedure was shown to be the best alternative therapy for immature teeth with necrotic pulp and apical infection. A 12 year old female with a history of trauma to her upper central incisor and a sinus tract was referred for endodontic treatment. She was an active orthodontic patient and had undergone regenerative endodontic treatment for the past 2 years. Clinical examination revealed no response to sensibility, percussion, and palpation tests. The preoperative radiograph showed an open apex and apical rarefaction...
February 2017: Restorative Dentistry & Endodontics
https://www.readbyqxmd.com/read/28131412/second-generation-platelet-concentrate-platelet-rich-fibrin-as-a-scaffold-in-regenerative-endodontics-a-case-series
#13
Hengameh Bakhtiar, Shahram Esmaeili, Setareh Fakhr Tabatabayi, Mohammad Reza Ellini, Mohammad Hossein Nekoofar, Paul M H Dummer
INTRODUCTION: The purpose of this case series was to report the clinical and radiographic results of a pulp regenerative procedure using platelet-rich fibrin (PRF), a second-generation platelet concentrate, in immature teeth with necrotic pulps. METHODS: Root canal revascularization using PRF was performed on 4 immature teeth with necrotic pulps. After access cavity preparation, the root canals were irrigated with low concentration sodium hypochlorite solution (1...
March 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28106508/gelma-encapsulated-hdpscs-and-huvecs-for-dental-pulp-regeneration
#14
A Khayat, N Monteiro, E E Smith, S Pagni, W Zhang, A Khademhosseini, P C Yelick
Pulpal revascularization is commonly used in the dental clinic to obtain apical closure of immature permanent teeth with thin dentinal walls. Although sometimes successful, stimulating bleeding from the periapical area of the tooth can be challenging and in turn may deleteriously affect tooth root maturation. Our objective here was to define reliable methods to regenerate pulp-like tissues in tooth root segments (RSs). G1 RSs were injected with human dental pulp stem cells (hDPSCs) and human umbilical vein endothelial cells (HUVECs) encapsulated in 5% gelatin methacrylate (GelMA) hydrogel...
February 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28106505/pulp-vascularization-during-tooth-development-regeneration-and-therapy
#15
REVIEW
C Rombouts, T Giraud, C Jeanneau, I About
The pulp is a highly vascularized tissue situated in an inextensible environment surrounded by rigid dentin walls, with the apical foramina being the only access. The pulp vascular system is not only responsible for nutrient supply and waste removal but also contributes actively to the pulp inflammatory response and subsequent regeneration. This review discusses the underlying mechanisms of pulp vascularization during tooth development, regeneration, and therapeutic procedures, such as tissue engineering and tooth transplantation...
February 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28072988/-retrospective-analysis-of-pulp-revascularization-in-immature-permanent-teeth-with-diffuse-pulpitis
#16
C F Peng, Y M Zhao, Y Yang, H Liu, M Qin
Objective: To evaluate the treatment effectiveness of revascularization in immature permanent teeth with diffuse pulpitis and to provide an alternative approach for the treatment of these teeth. Methods: Clinical and radiographic data were collected from 17 immature permanent teeth which were diagnosed as diffuse pulpitis and with their pulp extirpated at Emergency Department of Peking University School and Hospital of Stomatology. All these teeth were treated using pulp revascularization at Department of Pediatric Dentistry...
January 9, 2017: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/27955921/clinical-and-radiographic-outcomes-in-immature-permanent-necrotic-evaginated-teeth-treated-with-regenerative-endodontic-procedures
#17
Ling Li, Yihuai Pan, Liqin Mei, Jun Li
INTRODUCTION: Regenerative endodontics is a promising alternative treatment for immature permanent teeth with necrotic dental pulp. The present study assessed the time to resolution of clinical symptoms and radiographic changes in root dimensions in immature permanent necrotic teeth with dens evaginatus. METHODS: In this prospective study, clinical and radiographic data were collected for 20 teeth with dens evaginatus treated with a revascularization protocol for 1 year...
February 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/27912815/regenerative-endodontics-by-cell-homing
#18
REVIEW
Ling He, Juan Zhong, Qimei Gong, Bin Cheng, Sahng G Kim, Junqi Ling, Jeremy J Mao
Apical revascularization (AR) and platelet-rich plasma have been used to restore dental pulp vitality in infected immature permanent teeth. Two regenerative therapies are cell transplantation and cell homing. This article updates and benchmarks these therapies with cell homing. A case report concluded that AR increased root length; however, quantitative and statistical assessments disproved this. Regenerative endodontic therapies require prospective clinical trials demonstrating safety and efficacy. These therapies are intrinsically susceptible to procedural and patient variations...
January 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/27805884/root-canal-filling-after-revascularization-revitalization
#19
Hugo Plascencia, Álvaro Cruz, Mariana Díaz, Ana Laura Jiménez, Rodrigo Solís, Cesar Bernal
INTRODUCTION: Revascularization/revitalization therapy is considered an alternative procedure for management of teeth with an immature apex and necrotic pulp, mainly when root development is interrupted in the early phases of formation. However, this clinical treatment protocol should be considered a permanent procedure? METHOD: A maxillary central incisor with a previous and successful RR treatment was intentionally filled with a biocompatible material with the periapical tissues due to the patient's lack of adherence to the follow-up protocol...
2016: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/27788624/paradigm-shift-from-stem-cells-to-cell-free-regenerative-endodontic-procedures-a-critical-review
#20
Radovan Žižka, Jiří Šedý
Regenerative endodontic procedures of immature teeth with necrotic pulp have become a part of therapeutic endodontic spectrum and are considered as an alternative to calcium hydroxide or mineral trioxide aggregate apexification. In last decade, numerous case reports and series with usage of cell-free approaches known as revascularization, revitalization, or maturogenesis have been published. This cell-free approach prevails in clinical regenerative endodontics because of its relative ease of performance, lower financial demands, and absence of complications such as tumorigenesis of used stem cells...
February 1, 2017: Stem Cells and Development
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