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https://www.readbyqxmd.com/read/28346223/early-rectal-cancer-a-choice-between-local-excision-and-transabdominal-resection-a-review-of-the-literature-and-current-guidelines
#1
Giuseppe Pappalardo, Massimo Chiaretti
INTRODUCTION: Indication for Local Excision (LE) or Trans Abdominal Resections with Total Mesorectal Excision (TAR) in Early Rectal Cancer (ERC) are still controversial. MATERIAL OF STUDY: We reviewed meta-analyses, scientific societies guidelines, randomized and controlled clinical trials from 1999 to 2016 for a total of 146,231 patients. We included in our analysis the accuracy of different tools of investigation, the reliability of the endoscopic biopsies and compared the results of the various LE and TAR...
March 27, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28343958/simultanagnosia-does-not-affect-processes-of-auditory-gestalt-perception
#2
Johannes Rennig, Anna Lena Bleyer, Hans-Otto Karnath
Simultanagnosia is a neuropsychological deficit of higher visual processes caused by temporo-parietal brain damage. It is characterized by a specific failure of recognition of a global visual Gestalt, like a visual scene or complex objects, consisting of local elements. In this study we investigated to what extend this deficit should be understood as a deficit related to specifically the visual domain or whether it should be seen as defective Gestalt processing per se. To examine if simultanagnosia occurs across sensory domains, we designed several auditory experiments sharing typical characteristics of visual tasks that are known to be particularly demanding for patients suffering from simultanagnosia...
March 23, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28343741/time-as-context-the-influence-of-hierarchical-patterning-on-sensory-inference
#3
Juanita Todd, Anne Petherbridge, Bronte Speirs, Alexander Provost, Bryan Paton
Time, or more specifically temporal structure, is a critical variable in understanding how the auditory system uses acoustic patterns to predict input, and to filter events based on their relevance. A key index of this filtering process is the auditory evoked potential component known as mismatch negativity or MMN. In this paper we review findings of smaller MMN in schizophrenia through the lens of time as an influential contextual variable. More specifically, we review studies that show how MMN to a locally rare pattern-deviation is modulated by the longer-term context in which it occurs...
March 23, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28343000/evidence-for-similar-patterns-of-neural-activity-elicted-by-picture-and-word-based-representations-of-natural-scenes
#4
Manoj Kumar, Kara D Federmeier, Li Fei-Fei, Diane M Beck
A long-standing core question in cognitive science is whether different modalities and representation types (pictures, words, sounds, etc.) access a common store of semantic information. Although different input types have been shown to activate a shared network of brain regions, this does not necessitate that there is a common representation, as the neurons in these regions could still differentially process the different modalities. However, multi-voxel pattern analysis can be used to assess whether, e.g...
March 22, 2017: NeuroImage
https://www.readbyqxmd.com/read/28337089/evaluation-of-the-environmental-noise-levels-in-abuja-municipality-using-mobile-phones
#5
T Ibekwe, D Folorunso, A Ebuta, J Amodu, M Nwegbu, Z Mairami, I Liman, C Okebaram, C Chimdi, B Durogbola, H Suleiman, H Mamven, N Baamlong, E Dahilo, I Gbujie, P Ibekwe, O Nwaorgu
BACKGROUND: Noise remains a nuisance which impacts negatively on the physical, social and psychological wellbeing of man. It aggravates chronic illnesses like hypertension and other cardiopulmonary diseases. Unfortunately, increased activities from industrialization and technological transfers/drifts have tumultuously led to increased noise pollution in most of our fast growing cities today and hence the need for concerted efforts in monitoring and regulating our environmental noise. OBJECTIVE: To assess the equivalent noise level (Leq) in Abuja municipality and promote a simple method for regular assessment of Leq within our environment...
December 2016: Annals of Ibadan Postgraduate Medicine
https://www.readbyqxmd.com/read/28334281/blocking-c-fos-expression-reveals-the-role-of-auditory-cortex-plasticity-in-sound-frequency-discrimination-learning
#6
Livia de Hoz, Dorota Gierej, Victoria Lioudyno, Jacek Jaworski, Magda Blazejczyk, Hugo Cruces-Solís, Anna Beroun, Tomasz Lebitko, Tomasz Nikolaev, Ewelina Knapska, Israel Nelken, Leszek Kaczmarek
The behavioral changes that comprise operant learning are associated with plasticity in early sensory cortices as well as with modulation of gene expression, but the connection between the behavioral, electrophysiological, and molecular changes is only partially understood. We specifically manipulated c-Fos expression, a hallmark of learning-induced synaptic plasticity, in auditory cortex of adult mice using a novel approach based on RNA interference. Locally blocking c-Fos expression caused a specific behavioral deficit in a sound discrimination task, in parallel with decreased cortical experience-dependent plasticity, without affecting baseline excitability or basic auditory processing...
March 17, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28333967/reconstructing-spectral-cues-for-sound-localization-from-responses-to-rippled-noise-stimuli
#7
A John Van Opstal, Joyce Vliegen, Thamar Van Esch
Human sound localization in the mid-saggital plane (elevation) relies on an analysis of the idiosyncratic spectral shape cues provided by the head and pinnae. However, because the actual free-field stimulus spectrum is a-priori unknown to the auditory system, the problem of extracting the elevation angle from the sensory spectrum is ill-posed. Here we test different spectral localization models by eliciting head movements toward broad-band noise stimuli with randomly shaped, rippled amplitude spectra emanating from a speaker at a fixed location, while varying the ripple bandwidth between 1...
2017: PloS One
https://www.readbyqxmd.com/read/28303174/local-site-differences-in-survival-and-parasitism-of-periwinkles-littorina-sitkana-philippi-1846
#8
Mónica Ayala-Díaz, Jean M L Richardson, Bradley R Anholt
The periwinkle, Littorina sitkana, is found throughout the intertidal zone, often in isolated subpopulations. The majority of trematode parasites use snails as intermediate hosts, and decreased survivorship is often observed in snails infected with trematodes. Sampling L. sitkana from four sites in Barkley Sound, British Columbia, Canada, we test the effects of parasitic infection on snail survival using maximum likelihood and Bayesian approaches using the software MARK and WinBUGS. We found that survival of periwinkles and trematode community composition differed among sites, but survival and trematode prevalence were uncorrelated...
February 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28294357/expression-of-factors-involved-in-dental-pulp-physiopathological-processes-by-nemotic-human-pulpal-fibroblasts
#9
J Le Clerc, S Tricot-Doleux, P Pellen-Mussi, M Pérard, S Jeanne, F Pérez
AIM: To investigate in human pulp fibroblasts (HDPF) the expression of factors involved in dental pulp physiopathological processes and in an experimental model of cell activation called nemosis, and to compare the behaviour of pulp cell activation with sound lung fibroblasts MRC5, employed as a reference model for nemosis. METHODOLOGY: Nemotic response was induced in 3-dimensional cultures of HDPF and lung fibroblasts. The expressions of molecules involved in physiological (alkaline phosphatase, type I collagen) and in inflammatory processes (IL-6, CXCL8, CCL20, COX-2) were studied using real-time PCR...
March 10, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28293782/baha-implant-as-a-hearing-solution-for-single-sided-deafness-after-retrosigmoid-approach-for-the-vestibular-schwannoma-surgical-results
#10
Jan Boucek, Jan Vokral, Libor Cerny, Martin Chovanec, Jiří Skrivan, Eduard Zverina, Jan Betka, Michal Zabrodsky
Skull base tumors and, in particular, vestibular schwannoma (VS) are among the etiological reasons for single-sided deafness (SSD). Patients with SSD have problems in understanding speech in a noisy environment and cannot localize the direction of sounds. Baha is one of the most frequently used systems for SSD compensation. Out of 38 patients with SSD after retrosigmoid removal of VS who underwent testing with Baha softband, 16 were satisfied and were indicated for Baha implantation. Two surgical approaches have been used-the Nijmegen linear incision technique with subdermal thinning (Group I, implant BI300) and fast surgery technique without subdermal thinning (Group II, implant BIA400)...
March 14, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28293194/quantification-of-internal-stress-strain-fields-in-human-tendon-unraveling-the-mechanisms-that-underlie-regional-tendon-adaptations-and-mal-adaptations-to-mechanical-loading-and-the-effectiveness-of-therapeutic-eccentric-exercise
#11
REVIEW
Constantinos N Maganaris, Panagiotis Chatzistergos, Neil D Reeves, Marco V Narici
By virtue of their anatomical location between muscles and bones, tendons make it possible to transform contractile force to joint rotation and locomotion. However, tendons do not behave as rigid links, but exhibit viscoelastic tensile properties, thereby affecting the length and contractile force in the in-series muscle, but also storing and releasing elastic stain energy as some tendons are stretched and recoiled in a cyclic manner during locomotion. In the late 90s, advancements were made in the application of ultrasound scanning that allowed quantifying the tensile deformability and mechanical properties of human tendons in vivo...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28287173/single-mode-interface-states-in-heterostructure-waveguides-with-bragg-and-non-bragg-gaps
#12
Ya-Xian Fan, Tang-Qing Sang, Ting Liu, Lan-Lan Xu, Zhi-Yong Tao
Interface states can always arise in heterostructures that consist of two or more (artificial) materials with topologically different energy bands. The gapped band structure can be classified by the Chern number (a topological invariant) generally or the Zak phase in one-dimensional periodic systems. Recently, topological properties have been employed to investigate the interface states occurring at the connecting regions of the heterostructures of mechanical isostatic lattices and acoustical waveguides. Here, we study this heterostructure phenomenon by carefully connecting two corrugated stainless steel waveguides with Bragg and non-Bragg gaps at approximately the same frequency...
March 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28285921/brain-regions-for-sound-processing-and-song-release-in-a-small-grasshopper
#13
Mit Balvantray Bhavsar, Andreas Stumpner, Ralf Heinrich
We investigated brain regions - mostly neuropils - that process auditory information relevant for the initiation of response songs of female grasshoppers Chorthippus biguttulus during bidirectional intraspecific acoustic communication. Male-female acoustic duets in the species Ch. biguttulus require the perception of sounds, their recognition as a species- and gender-specific signal and the initiation of commands that activate thoracic pattern generating circuits to drive the sound-producing stridulatory movements of the hind legs...
March 9, 2017: Journal of Insect Physiology
https://www.readbyqxmd.com/read/28280544/the-influence-of-sea-ice-wind-speed-and-marine-mammals-on-southern-ocean-ambient-sound
#14
Sebastian Menze, Daniel P Zitterbart, Ilse van Opzeeland, Olaf Boebel
This paper describes the natural variability of ambient sound in the Southern Ocean, an acoustically pristine marine mammal habitat. Over a 3-year period, two autonomous recorders were moored along the Greenwich meridian to collect underwater passive acoustic data. Ambient sound levels were strongly affected by the annual variation of the sea-ice cover, which decouples local wind speed and sound levels during austral winter. With increasing sea-ice concentration, area and thickness, sound levels decreased while the contribution of distant sources increased...
January 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28272854/comparative-study-of-extralevator-vs-conventional-abdominoperineal-excision-in-a-single-centre-in-the-developing-world
#15
M Oostenbroek, E Coetzee, A Boutall, R Baigrie, P Goldberg
ABSTRACT: Abdominoperineal excision (APE) is used to resect cancers in the distal rectum and anus where sphincterpreserving surgery is not possible. It is associated with increased local recurrence rates compared to anterior resection. The extralevator abdominoperineal excision (ELAPE) was developed to reduce local recurrence and was widely adopted without sound evidence. AIM: To compare the short-term (2 years) outcomes of patients managed with ELAPE to those with conventional APE in a single institution in a developing country...
November 2016: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28269103/effect-of-importance-sampling-on-robust-segmentation-of-audio-cough-events-in-noisy-environments
#16
Jesus Monge-Alvarez, Carlos Hoyos-Barcelo, Paul Lesso, Javier Escudero, Keshav Dahal, Pablo Casaseca-de-la-Higuera
This paper proposes a new cough detection system based on audio signals acquired from conventional smartphones. The system relies on local Hu moments to characterize cough events and a Λ-NN classifier to distinguish cough events from non-cough ones (speech, laugh, sneeze, etc.) and noisy sounds. To deal with the unbalance between classes, we employ Distinct-Borderline2 Synthetic Minority Oversampling Technique and a bespoke cost matrix. The system additionally features a post-processing module to avoid isolated false negatives and, this way, increases sensitivity...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269101/detection-of-binaural-interaction-in-free-field-evoked-auditory-brainstem-responses-by-time-scale-representations
#17
Erik Schebsdat, Horst Hessel, Harald Seidler, Daniel J Strauss
The so called β-wave of the binaural interaction component (BIC) in auditory brainstem responses (ABR) has been shown to be an objective measure for binaural interaction (BI). This component is the arithmetical difference between the sum of the monaurally evoked ABRs and the binaurally evoked ABR. Unfortunately, these neural responses are known to be very fragile and as a result the calculated BIC. An additional issue is, that the findings of this measurement are predominantly needed in people with hearing loss who may use hearing devices like hearing aids (HA) or cochlear implants (CI), thus they are not able to use headphones (like in conventional ABR measurements) during the detection of possible BI...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269094/resonance-based-respiratory-sound-decomposition-aiming-at-localization-of-crackles-in-noisy-measurements
#18
Sezer Ulukaya, Gorkem Serbes, Yasemin P Kahya
In this work, resonance based decomposition of lung sounds that aims to separate wheeze, crackle and vesicular sounds into three individual channels while automatically localizing crackles for both synthetic and real data is presented. Previous works focus on stationary-non stationary discrimination to separate crackles and vesicular sounds disregarding wheezes which are stationary as compared to crackles. However, wheeze sounds include important cues about the underlying pathology. Using two different threshold methods and synthetic sound generation scenarios in the presence of wheezes, resonance based decomposition performs 89...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28261053/auditory-spatial-recalibration-in-congenital-blind-individuals
#19
Sara Finocchietti, Giulia Cappagli, Monica Gori
Blind individuals show impairments for auditory spatial skills that require complex spatial representation of the environment. We suggest that this is partially due to the egocentric frame of reference used by blind individuals. Here we investigate the possibility of reducing the mentioned auditory spatial impairments with an audio-motor training. Our hypothesis is that the association between a motor command and the corresponding movement's sensory feedback can provide an allocentric frame of reference and consequently help blind individuals in understanding complex spatial relationships...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28260394/evidence-for-behaviorally-segregated-spatio-temporally-overlapping-subnetworks-in-phantom-sound-perception
#20
Anusha Mohan, Nicole Moreno, Jae-Jin Song, Dirk De Ridder, Sven Vanneste
One of the most intriguing questions in neuroscience is to understand the mechanism of information transfer between different brain areas. Recently, network theory has gained traction and is at the forefront of providing a possible explanation to not only the mechanism of information transfer, but also in the identification of different neuropathologies. The perception of a phantom ringing in the ear called tinnitus, similar to other neuropathologies, has been shown to be accompanied by aberrant functional connectivity between different brain areas...
March 6, 2017: Brain Connectivity
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