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https://www.readbyqxmd.com/read/28809977/correlation-between-collective-and-molecular-dynamics-in-ph-responsive-cyclodextrin-based-hydrogels
#1
C Bottari, L Comez, S Corezzi, F D'Amico, A Gessini, A Mele, C Punta, L Melone, A Pugliese, C Masciovecchio, B Rossi
UV Raman and Brillouin light scattering (BLS) experiments have been used in this study to explore the complex phase change behavior occurring in pH-responsive polysaccharide hydrogels as a function of temperature. Due to the different physical quantities measured by the two techniques, the joint analysis of Raman and BLS spectra has provided an unprecedented large-scale characterization of the molecular rearrangements and of the different kinds of hydrophilic and hydrophobic interactions that cooperate to determine the phase transformation observed in these hydrogels during the heating of the gel...
August 15, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28798010/mobile-phone-detection-of-semantic-location-and-its-relationship-to-depression-and-anxiety
#2
Sohrab Saeb, Emily G Lattie, Konrad P Kording, David C Mohr
BACKGROUND: Is someone at home, at their friend's place, at a restaurant, or enjoying the outdoors? Knowing the semantic location of an individual matters for delivering medical interventions, recommendations, and other context-aware services. This knowledge is particularly useful in mental health care for monitoring relevant behavioral indicators to improve treatment delivery. Local search-and-discovery services such as Foursquare can be used to detect semantic locations based on the global positioning system (GPS) coordinates, but GPS alone is often inaccurate...
August 10, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28797612/decentralized-manufacturing-of-cell-and-gene-therapies-overcoming-challenges-and-identifying-opportunities
#3
REVIEW
Richard P Harrison, Steven Ruck, Nicholas Medcalf, Qasim A Rafiq
Decentralized or "redistributed" manufacturing has the potential to revolutionize the manufacturing approach for cell and gene therapies (CGTs), moving away from the "Fordist" paradigm, delivering health care locally, customized to the end user and, by its very nature, overcoming many of the challenges associated with manufacturing and distribution of high volume goods. In departing from the traditional centralized model of manufacturing, decentralized manufacturing divides production across sites or geographic regions...
August 7, 2017: Cytotherapy
https://www.readbyqxmd.com/read/28796088/the-effect-of-citalopram-versus-a-placebo-on-central-auditory-processing-in-the-elderly
#4
Jose Fernando Polanski, Alexandra Dezani Soares, Liliane Desgualdo Pereira, Oswaldo Laercio de Mendonça Cruz
OBJECTIVE: Evaluate the effects of therapy with citalopram on the central auditory processing in the elderly measured by central auditory tests. STUDY DESIGN: Prospective, randomized, double-blind, placebo-controlled study. SETTING: Tertiary referral center. PATIENTS: Thirty-nine patients older than 60 years with normal hearing thresholds or symmetrical sensorineural hearing loss up to 70 dBHL, word-recognition score equal to or better than 70%, and diagnosed with central auditory processing disorders completed the study...
August 8, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28792518/rendering-visual-events-as-sounds-spatial-attention-capture-by-auditory-augmented-reality
#5
Scott A Stone, Matthew S Tata
Many salient visual events tend to coincide with auditory events, such as seeing and hearing a car pass by. Information from the visual and auditory senses can be used to create a stable percept of the stimulus. Having access to related coincident visual and auditory information can help for spatial tasks such as localization. However not all visual information has analogous auditory percepts, such as viewing a computer monitor. Here, we describe a system capable of detecting and augmenting visual salient events into localizable auditory events...
2017: PloS One
https://www.readbyqxmd.com/read/28791155/simulated-seal-scarer-sounds-scare-porpoises-but-not-seals-species-specific-responses-to-12%C3%A2-khz-deterrence-sounds
#6
Lonnie Mikkelsen, Line Hermannsen, Kristian Beedholm, Peter Teglberg Madsen, Jakob Tougaard
Acoustic harassment devices (AHD) or 'seal scarers' are used extensively, not only to deter seals from fisheries, but also as mitigation tools to deter marine mammals from potentially harmful sound sources, such as offshore pile driving. To test the effectiveness of AHDs, we conducted two studies with similar experimental set-ups on two key species: harbour porpoises and harbour seals. We exposed animals to 500 ms tone bursts at 12 kHz simulating that of an AHD (Lofitech), but with reduced output levels (source peak-to-peak level of 165 dB re 1 µPa)...
July 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28771568/laminar-differences-in-response-to-simple-and-spectro-temporally-complex-sounds-in-the-primary-auditory-cortex-of-ketamine-anesthetized-gerbils
#7
Markus K Schaefer, Manfred Kössl, Julio C Hechavarría
In mammals, acoustic communication plays an important role during social behaviors. Despite their ethological relevance, the mechanisms by which the auditory cortex represents different communication call properties remain elusive. Recent studies have pointed out that communication-sound encoding could be based on discharge patterns of neuronal populations. Following this idea, we investigated whether the activity of local neuronal networks, such as those occurring within individual cortical columns, is sufficient for distinguishing between sounds that differed in their spectro-temporal properties...
2017: PloS One
https://www.readbyqxmd.com/read/28770260/disentangling-defects-and-sound-modes-in-disordered-solids
#8
Sven Wijtmans, M Lisa Manning
We develop a new method to isolate localized defects from extended vibrational modes in disordered solids. This method augments particle interactions with an artificial potential that acts as a high-pass filter: it preserves small-scale structures while pushing extended vibrational modes to higher frequencies. The low-frequency modes that remain are "bare" defects; they are exponentially localized without the quadrupolar tails associated with elastic interactions. We demonstrate that these localized excitations are excellent predictors of plastic rearrangements in the solid...
August 3, 2017: Soft Matter
https://www.readbyqxmd.com/read/28768878/controllable-biomimetic-birdsong
#9
Aryesh Mukherjee, Shreyas Mandre, L Mahadevan
Birdsong is the product of the controlled generation of sound embodied in a neuromotor system. From a biophysical perspective, a natural question is that of the difficulty of producing birdsong. To address this, we built a biomimetic syrinx consisting of a stretched simple rubber tube through which air is blown, subject to localized mechanical squeezing with a linear actuator. A large static tension on the tube and small dynamic variations in the localized squeezing allow us to control transitions between three states: a quiescent state, a periodic state and a solitary wave state...
August 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28765535/a-highly-attenuating-and-frequency-tailorable-annular-hole-phononic-crystal-for-surface-acoustic-waves
#10
B J Ash, S R Worsfold, P Vukusic, G R Nash
Surface acoustic wave (SAW) devices are widely used for signal processing, sensing and increasingly for lab-on-a-chip applications. Phononic crystals can control the propagation of SAW, analogous to photonic crystals, enabling components such as waveguides and cavities. Here we present an approach for the realisation of robust, tailorable SAW phononic crystals, based on annular holes patterned in a SAW substrate. Using simulations and experiments, we show that this geometry supports local resonances which create highly attenuating phononic bandgaps at frequencies with negligible coupling of SAWs into other modes, even for relatively shallow features...
August 2, 2017: Nature Communications
https://www.readbyqxmd.com/read/28764511/a-small-spacecraft-for-multipoint-measurement-of-ionospheric-plasma
#11
T M Roberts, K A Lynch, R E Clayton, J Weiss, D L Hampton
Measurement of ionospheric plasma is often performed by a single in situ device or remotely using cameras and radar. This article describes a small, low-resource, deployed spacecraft used as part of a local, multipoint measurement network. A B-field aligned sounding rocket ejects four of these spin-stabilized spacecraft in a cross pattern. In this application, each spacecraft carries two retarding potential analyzers which are used to determine plasma density, flow, and ion temperature. An inertial measurement unit and a light-emitting diode array are used to determine the position and orientation of the devices after deployment...
July 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28764486/robust-reproduction-of-sound-zones-with-local-sound-orientation
#12
Qiaoxi Zhu, Philip Coleman, Ming Wu, Jun Yang
Pressure matching (PM) and planarity control (PC) methods can be used to reproduce local sound with a certain orientation at the listening zone, while suppressing the sound energy at the quiet zone. In this letter, regularized PM and PC, incorporating coarse error estimation, are introduced to increase the robustness in non-ideal reproduction scenarios. Facilitated by this, the interaction between regularization, robustness, (tuned) personal audio optimization, and local directional performance is explored...
July 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28764473/combining-the-remote-microphone-technique-with-head-tracking-for-local-active-sound-control
#13
Woomin Jung, Stephen J Elliott, Jordan Cheer
This paper describes practical integration of the remote microphone technique with a head-tracking device in a local active noise control system. The formulation is first reviewed for the optimized observation filter and nearfield pressure estimation. The attenuation performance and stability of an adaptive active headrest system combined with the remote microphone technique are then studied. The accuracy of the nearfield estimation and the effect of the head-tracking on the control performance are investigated in real-time experiments...
July 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28764454/simulating-the-chan-hudspeth-experiment-on-an-active-excised-cochlear-segment
#14
Amir Nankali, Karl Grosh
Hearing relies on a series of coupled electrical, acoustical, and mechanical interactions inside the cochlea that enable sound processing. The local structural and electrical properties of the organ of Corti (OoC) and basilar membrane give rise to the global, coupled behavior of the cochlea. However, it is difficult to determine the root causes of important behavior, such as the mediator of active processes, in the fully coupled in vivo setting. An alternative experimental approach is to use an excised segment of the cochlea under controlled electrical and mechanical conditions...
July 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28764438/sound-source-localization-identification-accuracy-envelope-dependencies
#15
William A Yost
Sound source localization accuracy as measured in an identification procedure in a front azimuth sound field was studied for click trains, modulated noises, and a modulated tonal carrier. Sound source localization accuracy was determined as a function of the number of clicks in a 64 Hz click train and click rate for a 500 ms duration click train. The clicks were either broadband or high-pass filtered. Sound source localization accuracy was also measured for a single broadband filtered click and compared to a similar broadband filtered, short-duration noise...
July 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28764418/localization-and-separation-of-acoustic-sources-by-using-a-2-5-dimensional-circular-microphone-array
#16
Mingsian R Bai, Chang-Sheng Lai, Po-Chen Wu
Circular microphone arrays (CMAs) are sufficient in many immersive audio applications because azimuthal angles of sources are considered more important than the elevation angles in those occasions. However, the fact that CMAs do not resolve the elevation angle well can be a limitation for some applications which involves three-dimensional sound images. This paper proposes a 2.5-dimensional (2.5-D) CMA comprised of a CMA and a vertical logarithmic-spacing linear array (LLA) on the top. In the localization stage, two delay-and-sum beamformers are applied to the CMA and the LLA, respectively...
July 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28762949/laser-doppler-flowmetry-and-transcutaneous-oximetry-in-chronic-skin-ulcers-a-comparative-evaluation
#17
Edoardo Raposio, Nicolò Bertozzi, Rebecca Moretti, Eugenio Grignaffini, Michele P Grieco
INTRODUCTION/OBJECTIVE: Laser Doppler Flowmetry (LDF) and transcutaneous oximetry (TcpO2) are established methods for investigating cutaneous perfusion. To date, no study previously performed has compared data obtained from these 2 methodologies in cases of chronic cutaneous ulcers. MATERIALS AND METHODS: Laser Doppler Flowmetry and TcpO2 were performed in 25 consecutive outpatients with chronic lower limb ulcers (group A, experimental; 9 women and 16 men; mean age 67 years [range, 52-81 years]) and 25 age- and sex-matched healthy control subjects (group B, control) enrolled for the study...
April 27, 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28762045/hybrid-cochlear-implantation-quality-of-life-quality-of-hearing-and-working-performance-compared-to-patients-with-conventional-unilateral-or-bilateral-cochlear-implantation
#18
Kati Härkönen, Ilkka Kivekäs, Voitto Kotti, Ville Sivonen, Juha-Pekka Vasama
The objective of the present study is to evaluate the effect of hybrid cochlear implantation (hCI) on quality of life (QoL), quality of hearing (QoH), and working performance in adult patients, and to compare the long-term results of patients with hCI to those of patients with conventional unilateral cochlear implantation (CI), bilateral CI, and single-sided deafness (SSD) with CI. Sound localization accuracy and speech-in-noise test were also compared between these groups. Eight patients with high-frequency sensorineural hearing loss of unknown etiology were selected in the study...
July 31, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28756239/trading-of-dynamic-interaural-time-and-level-difference-cues-and-its-effect-on-the-auditory-motion-onset-response-measured-with-electroencephalography
#19
Christian F Altmann, Ryuhei Ueda, Benoit Bucher, Shigeto Furukawa, Kentaro Ono, Makio Kashino, Tatsuya Mima, Hidenao Fukuyama
Interaural time (ITD) and level differences (ILD) constitute the two main cues for sound localization in the horizontal plane. Despite extensive research in animal models and humans, the mechanism of how these two cues are integrated into a unified percept is still far from clear. In this study, our aim was to test with human electroencephalography (EEG) whether integration of dynamic ITD and ILD cues is reflected in the so-called motion-onset response (MOR), an evoked potential elicited by moving sound sources...
July 27, 2017: NeuroImage
https://www.readbyqxmd.com/read/28753360/mode-selection-in-compressible-active-flow-networks
#20
Aden Forrow, Francis G Woodhouse, Jörn Dunkel
Coherent, large-scale dynamics in many nonequilibrium physical, biological, or information transport networks are driven by small-scale local energy input. Here, we introduce and explore an analytically tractable nonlinear model for compressible active flow networks. In contrast to thermally driven systems, we find that active friction selects discrete states with a limited number of oscillation modes activated at distinct fixed amplitudes. Using perturbation theory, we systematically predict the stationary states of noisy networks and find good agreement with a Bayesian state estimation based on a hidden Markov model applied to simulated time series data...
July 14, 2017: Physical Review Letters
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