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1927 nm

Gregory A Aird, Jenna L Sitenga, Austin Huy Nguyen, Adam Vaudreuil, Christopher J Huerter
Treatment of disseminated superficial actinic porokeratosis (DSAP) is poorly standardized. The present review seeks to comprehensively discuss the potential for laser and light modalities in the treatment of DSAP. A systematic review of light and laser treatment modalities was conducted to include 26 cases of patients with DSAP. Systematic review resulted in 14 articles to be included. Photodynamic therapy (PDT) overall was the least successful treatment modality, with clinical improvement seen in a minority of patients (MAL-PDT: N = 9 patients, 33...
February 27, 2017: Lasers in Medical Science
Elizabeth R C Geddes, Ashlyn B Stout, Paul M Friedman
BACKGROUND: Melasma presents a significant challenge to laser surgeons. Aggressive treatments often result in rebound melasma or post-inflammatory pigmentary alteration. Recent reports suggest melasma pathogenesis may have a vascular component. Spectrocolorimetry can detect subtle or sub-clinical telangiectatic erythema within melasma lesions. For certain patients identified by spectrocolorimetry, effective melasma treatment may include vascular-targeted therapy together with pigment-specific treatment modalities...
January 2017: Lasers in Surgery and Medicine
Hilary Reich, Irmina Wallander, Lacie Schulte, Molly Goodier, Brian Zelickson
METHODS: In this split-face, evaluator-blinded study, 18 subjects were randomly assigned to receive either the SSR or NFL treatments on each side of the face. For the SSR facial sides subjects followed two morning-evening regimens. On the NFL sides subjects were treated 3 times with the 1927-nm laser at 4-week intervals. Three physician evaluators were asked to rate hyperpigmentation, global photoaging, and ne lines and wrinkles for each side of the face at baseline and at 3 months using a 5-point scale...
November 1, 2016: Journal of Drugs in Dermatology: JDD
Steven R Cohen, Ashley Goodacre, Soobin Lim, Jennifer Johnston, Cory Henssler, Brian Jeffers, Ahmad Saad, Tracy Leong
BACKGROUND: Fractional lasers were introduced to provide increased safety, while maintaining high efficacy and patient satisfaction. Patients with virtually all Fitzpatrick skin types could be safely treated using a wide spectrum of wavelengths and a broad array of skin conditions, and aging could be addressed. Although safety studies have been reported for ablative CO2 and erbium lasers, surprisingly few data are available on adverse events and complications associated with fractional lasers...
February 2017: Aesthetic Plastic Surgery
Nicholas A Ross, Lara E Rosenbaum, Nazanin Saedi, Kenneth A Arndt, Jeffrey S Dover
Disseminated superficial actinic porokeratosis (DSAP) is an inherited disorder of keratinization readily diagnosed through clinical and histologic examination. While generally benign in nature, the lesions can have profound psychosocial implications for patients. Although no cure exists, a number of treatment modalities, from topical medications to laser and light devices, have been reported with variable success. The authors report two cases of DSAP treated with the 1927-nm thulium fiber fractional laser along with a review of the treatment literature for DSAP...
2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
Robert Finney, Richard Torbeck, Nazanin Saedi
BACKGROUND AND OBJECTIVES: A 28-year-old female presented with extensive scarring after a traumatic injury to her right lower extremity. She had been hit by a vehicle one year prior to presentation and had several open fractures with extensive overlying cutaneous damage, which required multiple surgeries and skin grafts. She had limited range of motion of the affected limb secondary to scar contracture. STUDY DESIGN/MATERIALS AND METHODS: The patient received 6 treatments with a non-ablative fractional resurfacing (NAFR) device with two wavelengths (Fraxel DUAL, Solta Medical, Hayward, CA) spaced 4-8 weeks apart...
February 2016: Lasers in Surgery and Medicine
Jaleh Varshosaz, Mohsen Minaiyan, Mohammad Reza Zaki, Milad Fathi, Hossein Jaleh
Bupropion HCl is an atypical antidepressant drug with rapid and high first-pass metabolism. Sustained release dosage form of this drug is suggested for reducing its side effects which are mainly seizures. The aim of the present study was to design pulmonary agar nanospheres of bupropion HCl with effective systemic absorption and extended release properties. Bupropion HCl was encapsulated in agar nanospheres by ionic gelation, and characterized for physical and release properties. Pharmacokinetic studies on nanospheres were performed on rats by intratracheal spraying of 5 mg/kg of drug in form of nanospheres compared to intravenous and pulmonary delivery of the same dose as simple solution of the drug...
July 2016: Drug Delivery
Jeremy A Brauer, David H McDaniel, Bradley S Bloom, Kavitha K Reddy, Leonard J Bernstein, Roy G Geronemus
BACKGROUND: Long-term exposure to sunlight, including ultraviolet A and B, produces signs associated with photoaging and photodamage, including laxity and discoloration of the skin. Initial laser treatment for dyspigmentation included the use of ablative lasers, followed by Q-switched lasers and more recently fractional lasers. OBJECTIVE: We investigated the safety and efficacy of a fractionated 1927nm non-ablative thulium laser for the treatment of photo-induced pigmentation...
November 2014: Journal of Drugs in Dermatology: JDD
Lisa Y Xu, Suzanne L Kilmer, E Victor Ross, Mathew M Avram
Non-ablative fractional laser procedures have become increasingly popular since their introduction in 2004. The fractional 1,927 nm thulium laser is a non-ablative device that penetrates up to 300 μm in the skin and the 1,550 nm erbium:glass laser penetrates up to 1,400 μm. These procedures are considered minimally invasive with a high safety profile; therefore, infectious complications are exceedingly rare. However, we report five recent cases of bacterial infection with both gram-positive and gram-negative organisms following treatment with the fractional 1550/1927 nm laser approximately 1 day to 1 week post-procedure...
February 2015: Lasers in Surgery and Medicine
Sang Min Lee, Myoung Shin Kim, Youn Jin Kim, Chong Hyun Won, Mi Woo Lee, Jee Ho Choi, Kee Chan Moon, Sung Eun Chang
BACKGROUND: Non-ablative fractional laser photothermolysis (NAFP) has been used effectively in the treatment of photodamaged skin and scars, with short post-operative recovery times; but, studies evaluating its adverse events and complication rates in Asian population have been limited. OBJECTIVE: To determine the frequency and range of adverse events associated with NAFP treatment in Korean patients. MATERIALS AND METHODS: We retrospectively evaluated the outcomes of 754 1550-nm erbium-doped and 102 1927-nm thulium fiber fractional laser treatments in patients with skin phototypes III-IV treated at a single center...
August 2014: Journal of Dermatological Treatment
Stephanie G Y Ho, C K Yeung, Nicola P Y Chan, Samantha Y Shek, Henry H L Chan
BACKGROUND: A new fractional photothermolysis device is used in our retrospective study to treat melasma in Chinese patients. OBJECTIVES: To evaluate the efficacy and safety of the 1927 nm fractional thulium fiber laser in the treatment of melasma in Chinese patients. METHODS: Eleven melasma patients who received treatment between November 2009 and May 2010 were included. Photographic images at baseline and follow-up were assessed for clinical efficacy and complications by two independent and blinded physicians...
August 2013: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
(no author information available yet)
No abstract text is available yet for this article.
November 2012: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
Elliot T Weiss, Jeremy A Brauer, Robert Anolik, Kavitha K Reddy, Julie K Karen, Elizabeth K Hale, Lori A Brightman, Leonard Bernstein, Roy G Geronemus
BACKGROUND: Actinic keratoses (AK) are precancerous epidermal proliferations commonly present on chronically sun-damaged skin. These lesions are among the most often treated dermatologic conditions. OBJECTIVE: We sought to investigate the 6-month safety, tolerance, and efficacy of nonablative 1927-nm fractional resurfacing of facial AK. METHODS: This was a prospective clinical trial of 24 individuals with facial photodamage and AK receiving up to 4 treatments with the fractionated 1927-nm nonablative thulium laser...
January 2013: Journal of the American Academy of Dermatology
Andrei I Metelitsa
No abstract text is available yet for this article.
July 2012: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Kristel D Polder, Anum Mithani, April Harrison, Suzanne Bruce
OBJECTIVES: Macular seborrheic keratoses (SK) are common, benign growths. A novel fractionated 1927-nm thulium fiber laser was selected to investigate efficacy and safety in the clearance of macular SK in nonfacial areas at a private dermatologic laser center. STUDY DESIGN: Six subjects (average age 56.8 ± 9.5) with at least four 3-mm or larger macular SK on one extremity, neck, or chest were enrolled and provided informed consent. Subjects received three treatments at 3- to 4-week intervals...
July 2012: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Georg Stoeppler, Daniela Parisi, Mauro Tonelli, Marc Eichhorn
We present the first demonstration of a 792 nm diode-pumped Tm3+:LiLuF4 thin-disk laser operation around 1.9 μm. In multimode configuration, up to 21 W of output power and a maximal slope efficiency of 49% with an optical-to-optical efficiency of 40% was demonstrated. A tuning range from 1899 nm to 1927 nm could be achieved by inserting an etalon into the cavity.
April 1, 2012: Optics Letters
Frithjof Haxsen, Dieter Wandt, Uwe Morgner, Jörg Neumann, Dietmar Kracht
We report on monotonically positively chirped pulse operation of a hybridly mode-locked thulium fiber laser. Dispersion management was realized with a small-core, high-NA fiber providing normal dispersion in the 2 μm wavelength region. The laser delivered pulses with 0.7 nJ energy at the 1927 nm center wavelength and sub-500-fs pulse duration after compression.
March 15, 2012: Optics Letters
Emma J Murphy, Amandine Maréchal, Anthony W Segal, Peter R Rich
Despite the fact that ferrous myeloperoxidase (MPO) can bind both O(2) and NO, its ability to bind CO has been questioned. UV/visible spectroscopy was used to confirm that CO induces small spectral shifts in ferrous MPO, and Fourier transform infrared difference spectroscopy showed definitively that these arose from formation of a heme ferrous-CO compound. Recombination rates after CO photolysis were monitored at 618 and 645 nm as a function of CO concentration and pH. At pH 6.3, k(on) and k(off) were 0.14 mM(-1) x s(-1) and 0...
March 16, 2010: Biochemistry
F Cornacchia, D Parisi, C Bernardini, A Toncelli, M Tonelli
In this work we report the spectroscopy and laser results of several Thulium doped BaY(2)F(8) single crystals grown using the Czochralski technique. The doping concentration is between 2at.% and 18at.%. We performed room temperature laser experiments pumping the samples with a laser diode at 789 nm obtaining 61% as maximum optical-to-optical efficiency with a maximum output power of 290 mW and a minimum lasing threshold of 26 mW. The lasing wavelength changed with the dopant concentration from 1927 nm up to 2030 nm and the nature of the transition changed from purely electronic to vibronic, accordingly...
May 3, 2004: Optics Express
R Sivaramakrishnan, J V Michael
High-temperature rate constant experiments on OH with the five large (C(5)-C(8)) saturated hydrocarbons n-heptane, 2,2,3,3-tetramethylbutane (2,2,3,3-TMB), n-pentane, n-hexane, and 2,3-dimethylbutane (2,3-DMB) were performed with the reflected-shock-tube technique using multipass absorption spectrometric detection of OH radicals at 308 nm. Single-point determinations at approximately 1200 K on n-heptane, 2,2,3,3-TMB, n-hexane, and 2,3-DMB were previously reported by Cohen and co-workers; however, the present work substantially extends the database to both lower and higher temperature...
April 30, 2009: Journal of Physical Chemistry. A
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