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Complication rate of ovarian surgery

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https://www.readbyqxmd.com/read/28223182/minimally-invasive-surgical-staging-in-early-stage-ovarian-carcinoma-a-systematic-review-and-meta-analysis
#1
REVIEW
Giorgio Bogani, Chiara Borghi, Umberto Leone Roberti Maggiore, Antonino Ditto, Mauro Signorelli, Fabio Martinelli, Valentina Chiappa, Carlos Lopez, Ilaria Sabatucci, Cono Scaffa, Alice Indini, Simone Ferrero, Domenica Lorusso, Francesco Raspagliesi
Few studies investigated the efficacy and safety of minimally invasive surgery (MIS) for the treatment of early stage epithelial ovarian cancer (eEOC). In this context, we aimed to review the current evidence comparing laparoscopy and laparotomic approach for staging procedures in eEOC This systematic review was registered in the International Prospective Register of Systematic Review. Overall, 3,065 patients were included: 1,450 undergoing laparoscopy and 1,615 undergoing laparotomic staging. Patients undergoing laparoscopy experienced a longer (but not statistically significant) operative time (WMD: 28...
February 18, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28187092/incidence-of-venous-thromboembolism-by-type-of-gynecologic-malignancy-and-surgical-modality-in-the-national-surgical-quality-improvement-program
#2
Ashley Graul, Nawar Latif, Xiaochen Zhang, Lorraine T Dean, Mark Morgan, Robert Giuntoli, Robert Burger, Sarah Kim, Emily Ko
BACKGROUND: Women with gynecologic cancer are at higher risk of venous thromboembolism (VTE) due to malignancy, pelvic surgery, increased age, and frequently comorbidities. The rate of VTE among different gynecologic cancers and relative to benign gynecologic surgeries has not been reported in a nationally representative cohort. METHODS: Using the American College of Surgeons National Surgical Quality Improvement Program database, gynecologic surgeries were identified retrospectively from 2006 to 2012...
March 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28159407/efforts-at-maximal-cytoreduction-improve-survival-in-ovarian-cancer-patients-even-when-complete-gross-resection-is-not-feasible
#3
Sumer Wallace, Amanika Kumar, Michaela Mc Gree, Amy Weaver, Andrea Mariani, Carrie Langstraat, Sean Dowdy, Jamie Bakkum-Gamez, William Cliby
OBJECTIVE: We sought to determine survival associated with residual disease (RD) after primary debulking surgery (PDS) for advanced ovarian cancer (OC), and evaluate impact on complications and survival after practice changes to improve PDS. METHODS: Outcome variables were collected for patients undergoing PDS for FIGO (2009) stage IIIC OC from 2003 to 2011. The cohort was divided into time periods (2003-2006 vs. 2007-2011), before and after cytoreduction standardization...
January 31, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28152542/comparison-of-two-protocols-for-the-management-of-asymptomatic-postmenopausal-women-with-adnexal-tumours-a-randomised-controlled-trial-of-rmi-rcog-vs-simple-rules
#4
Natalie Nunes, Gareth Ambler, Xulin Foo, Joel Naftalin, Grigoris Derdelis, Martin Widschwendter, Davor Jurkovic
BACKGROUND: Adnexal tumours are frequently diagnosed in asymptomatic postmenopausal women due to more liberal use of modern high-resolution imaging. This study's objective was to determine if there would be a difference in the intervention rates when using the Simple Rules Management Protocol (SRMP) as compared to the Risk of Malignancy Index in the Royal College of Obstetricians and Gynaecologists guideline (RMI/RCOG). METHODS: This was a prospective randomised controlled trial with the participants and the researchers non-blinded, and the surgeons and pathologists blinded...
February 2, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28104497/robot-assisted-surgery-in-gynecologic-cancers
#5
REVIEW
V Zanagnolo, A Garbi, M T Achilarre, L Minig
Robotic-assisted surgery is a technological advancement that facilitates the application of minimally invasive techniques for complex operations in gynecological oncology. The objective of this article is to review the literature regarding the role of robotic-assisted surgery to treat women with gynecologic cancers. The majority of publications on robotic surgery are still retrospective or descriptive in nature, however, the data for managing patients with a robotic assisted approach shows comparable, and at times an improved outcomes compared to both laparoscopy (2D) and laparotomy approaches...
January 16, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28086838/clinical-characteristics-of-genital-chlamydia-infection-in-pelvic-inflammatory-disease
#6
Sung Taek Park, Suk Woo Lee, Min Jeong Kim, Young Mo Kang, Hye Min Moon, Chae Chun Rhim
BACKGROUND: Chlamydia infection in acute pelvic inflammatory disease (PID) is associated with serious complications including ectopic pregnancy, tubal infertility, Fitz-Hugh-Curtis syndrome and tubo-ovarian abscess (TOA). This study compared clinical and laboratory data between PID with and without chlamydia infection. METHODS: The medical records of 497 women who were admitted with PID between 2002 and 2011 were reviewed. The patients were divided into two groups (PID with and without chlamydia infection), which were compared in terms of the patients' characteristics, clinical presentation, and laboratory findings, including inflammatory markers...
January 13, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28062019/care-delivery-patterns-processes-and-outcomes-for-primary-ovarian-cancer-surgery-a-population-based-review-using-a-national-administrative-database
#7
Saad Shakeel, Laurie Elit, Noori Akhtar-Danesh, Laura Schneider, Christian Finley
OBJECTIVES: In this pan-Canadian study, we sought to elucidate the current state of surgical care for primary ovarian cancers and factors influencing selected short-term outcomes; these were in-hospital mortality (IHM), major complications (MCs), failure-to-rescue (FTR), and hospital length of stay (LOS). METHODS: We created a population cohort using inpatient admission records from the Canadian Institute of Health Information data set (2004-2012). Multilevel logistic regression and flexible parametric survival analyses, adjusted for hospital clustering effect, were conducted to determine the effect of patient-specific factors (i...
January 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/27995454/neoadjuvant-chemotherapy-increases-r0-cytoreduction-rate-but-does-not-improve-final-outcome-in-advanced-epithelial-ovarian-cancer
#8
Heriberto Medina-Franco, Rubén Cortés-González, Fernando Lambreton-Hinojosa, Adrián Fimbres-Morales, Juan-Carlos Vargas-Siordia
BACKGROUND: Most epithelial ovarian cancers present in advanced stages. Traditional management is maximum cytoreductive effort followed by platinum-taxane-based chemotherapy. We hypothesized that providing all chemotherapy before surgery will increase the R0 cytoreductive rate and improve prognosis. METHODS: Patients with advanced epithelial ovarian carcinoma [International Federation of Gynecology and Obstetrics (FIGO) stages IIIC and IV without parenchymal metastasis] were included in a comparative study...
December 19, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27993479/feasibility-and-outcome-of-interval-debulking-surgery-ids-after-carboplatin-paclitaxel-bevacizumab-cpb-a-subgroup-analysis-of-the-mito-16a-mango-ov2a-phase-4-trial
#9
Gennaro Daniele, Domenica Lorusso, Giovanni Scambia, Sabrina C Cecere, Maria Ornella Nicoletto, Enrico Breda, Nicoletta Colombo, Grazia Artioli, Lucia Cannella, Giovanni Lo Re, Francesco Raspagliesi, Giuseppa Maltese, Vanda Salutari, Gabriella Ferrandina, Stefano Greggi, Alessandra Baldoni, Alice Bergamini, Maria Carmela Piccirillo, Germana Tognon, Irene Floriani, Simona Signoriello, Francesco Perrone, Sandro Pignata
BACKGROUND: Few data are available on the outcome of surgery after a bevacizumab-containing regimen. The MITO 16A- MaNGO OV2A phase 4 trial evaluates the outcomes of first-line CPB in a clinical-practice-like setting. Here we present the results of the subgroup of patients undergoing IDS after neoadjuvant treatment or suboptimal primary surgery. METHODS: 400 chemonaïve epithelial ovarian cancer patients, age≥18, ECOG PS 0-2 were eligible to receive C (AUC 5 d1, q21) plus P (175mg/m(2) d1, q21) and B (15mg/kg d1 q21) for 6cycles followed by B maintenance until cycle 22nd...
December 16, 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27958619/evaluation-of-urgent-multivisceral-resections-due-to-complications-resulting-from-an-advanced-ovarian-cancer
#10
Tomasz Miłek, Witold Woźniak, Piotr Porzycki, Alkalayla Habib, Agnieszka Timorek, Piotr Ciostek, Włodzimierz Sawicki, Krzysztof Cendrowski
BACKGROUND: Unlike other solid tumors (i.e. pancreas, gallbladder, stomach), an ovarian cancer is responsive to a systemic treatment with platinum derivates in 80% of patients. This apparent chemosensitivity justifies a broader surgical approach. A cytoreductive, "tumor-debulking" surgery is defined as an attempt to remove in a maximum degree all visible and detect-able lesions. Despite treatment, the advancement of the disease very often leads to complications defined as "surgical" and life-threatening...
2016: Ginekologia Polska
https://www.readbyqxmd.com/read/27914243/efficacy-and-safety-of-bevacizumab-containing-neoadjuvant-therapy-followed-by-interval-debulking-surgery-in-advanced-ovarian-cancer-results-from-the-anthalya-trial
#11
Roman Rouzier, Sébastien Gouy, Frédéric Selle, Eric Lambaudie, Anne Floquet, Virginie Fourchotte, Christophe Pomel, Pierre-Emmanuel Colombo, Elsa Kalbacher, Sandrine Martin-Francoise, Raffaele Fauvet, Philippe Follana, Anne Lesoin, Fabrice Lecuru, Youssef Ghazi, Julien Dupin, Elisabeth Chereau, Sarah Zohar, Paul Cottu, Florence Joly
AIM: To investigate whether adding bevacizumab to neoadjuvant carboplatin-paclitaxel (CP) helps achieve optimal debulking, measured by complete resection rate (CRR) at interval debulking surgery (IDS), in patients with initially unresectable International Federation of Gynecology and Obstetrics stage IIIC/IV ovarian, tubal or peritoneal adenocarcinoma. METHODS: Multicentre, open-label, non-comparative phase II study. Ninety-five patients randomised (2:1) to receive four cycles of neoadjuvant CP ±3 concomitant cycles of bevacizumab 15 mg/kg (BCP) followed by IDS...
January 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/27896508/trends-in-mortality-after-primary-cytoreductive-surgery-for-ovarian-cancer-a-systematic-review-and-metaregression-of-randomized-clinical-trials-and-observational-studies
#12
REVIEW
Violante Di Donato, Evangelos Kontopantelis, Giovanni Aletti, Assunta Casorelli, Ilaria Piacenti, Giorgio Bogani, Francesca Lecce, Pierluigi Benedetti Panici
BACKGROUND: Primary cytoreductive surgery (PDS) followed by platinum-based chemotherapy is the cornerstone of treatment and the absence of residual tumor after PDS is universally considered the most important prognostic factor. The aim of the present analysis was to evaluate trend and predictors of 30-day mortality in patients undergoing primary cytoreduction for ovarian cancer. METHODS: Literature was searched for records reporting 30-day mortality after PDS. All cohorts were rated for quality...
November 28, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27880944/opportunistic-salpingectomy-does-not-affect-ovarian-reserve-or-surgical-outcomes-in-patients-undergoing-laparoscopic-myomectomy
#13
Taejong Song, San-Hui Lee, Woo Young Kim, Eun Jin Heo, Tae-Joong Kim
OBJECTIVE: To determine whether opportunistic salpingectomy in patients undergoing laparoscopic myomectomy has any deleterious effects on ovarian reserve and surgical risk. STUDY DESIGN: We performed a retrospective review of patients who had no desire for future child bearing and who were undergoing laparoscopic myomectomy for symptomatic myomas at 4 institutions. Among them, 41 patients concurrently underwent opportunistic salpingectomy (the opportunistic salpingectomy group) and 65 patients did not undergo salpingectomy at the time of laparoscopic myomectomy (the no-salpingectomy group)...
November 24, 2016: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/27856389/mini-laparoscopy-of-removal-partial-adnexae-at-the-time-of-hysterectomy
#14
António Gutierrez Setúbal, João Sequeira Alves, Olga Lavado, Joana Faria
STUDY OBJECTIVE: To describe our technique of mini laparoscopic adnexectomy or salpingectomy at the time of total laparoscopic hysterectomy DESIGN: Step-by-step video explanation of our technique SETTING: The advantages of laparoscopic surgery have been widely recognised in the past two decades: improved vision, exposure, reduction in operative trauma because of smaller incisions and more gentle tissue´s handling, that result in a faster postoperative recovery. The technology development has allowed the use of smaller caliber instruments while maintaining the high standard surgical performance...
November 14, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27836207/primary-debulking-surgery-of-the-upper-abdomen-and-the-diaphragm-with-a-plasma-device-surgery-system-for-advanced-ovarian-cancer
#15
Gloria Cordeiro Vidal, Guillaume Babin, Denis Querleu, Frédéric Guyon
OBJECTIVE: Electrically neutral argon plasma (PlasmaJet™) technology is a surgical option that helps to get an aggressive cytoreduction in selected patients with ovarian cancer because it can be directly applied by the surgeon to treat the tissue surface [1,2]. Upper abdominal surgical procedures are an important part of the surgery in these patients [3], there is a 22% complications rate when they are performed [4]. We present a surgical approach to ovarian cancer debulking using PlasmaJet™...
January 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/27810554/the-performance-and-safety-of-bilateral-salpingectomy-for-ovarian-cancer-prevention-in-the-united-states
#16
Gillian Elizabeth Hanley, Jessica Nell McAlpine, Celeste Leigh Pearce, Dianne Miller
BACKGROUND: Ovarian cancer is the leading cause of death due to gynecologic malignancy and the fifth most common cause of cancer deaths in developed countries. Recent evidence has indicated that the most common and lethal form of ovarian cancer originates in the distal fallopian tube, and recommendations for surgical removal of the fallopian tube (bilateral salpingectomy) at the time of other gynecologic surgeries (particularly hysterectomy and tubal sterilization) have been made, most recently by the American Congress of Obstetricians and Gynecologists...
November 1, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27779544/hyperthermic-intraperitoneal-perfusion-chemotherapy-and-cytoreductive-surgery-for-controlling-malignant-ascites-from-ovarian-cancer
#17
Mingchen Ba, Hui Long, Xiangliang Zhang, Yunqiang Tang, Yinbing Wu, Shuai Wang, Zhaofei Yan, Bohuo Zhang, Shuzhong Cui
BACKGROUND: Malignant ascites, a complication often seen in patients with ovarian cancer (OC), is difficult to treat, but hyperthermic intraperitoneal chemotherapy (HIPEC) has a good efficacy. OBJECTIVE: The aim of this study was to assess the efficacy of cytoreductive surgery (CRS) combined with HIPEC for controlling malignant ascites from OC. MATERIALS AND METHODS: From December 2009 until December 2014, 53 patients with OC and malignant ascites were treated with CRS and HIPEC...
November 2016: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27714520/the-use-of-transureteroureterostomy-during-ureteral-reconstruction-for-advanced-primary-or-recurrent-pelvic-malignancy-in-the-era-of-multimodal-therapy
#18
Junichiro Kawamura, Masaki Tani, Kimiaki Sumida, Takefumi Yazawa, Junya Kawasoe, Michihiro Yamamoto, Hideki Harada, Hidekazu Yamamoto, Masazumi Zaima
PURPOSE: Cancerous involvement of a ureter is sometimes encountered in pelvic surgery for malignancy. We usually perform transureteroureterostomy (TUU) in cases of unilateral lower ureteral cancerous involvement. We report the outcomes in patients treated with TUU in our institute. METHODS: We retrospectively reviewed the medical records of 11 patients who underwent TUU between June 2006 and September 2015. RESULTS: The primary disease was colon cancer in five patients, rectal cancer in four, and uterine cervical cancer and ovarian cancer in one patient each...
January 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/27702704/minimally-invasive-surgical-staging-for-ovarian-carcinoma-a-propensity-matched-comparison-with-traditional-open-surgery
#19
Antonino Ditto, Giorgio Bogani, Fabio Martinelli, Mauro Signorelli, Valentina Chiappa, Cono Scaffa, Alice Indini, Umberto Leone Roberti Maggiore, Domenica Lorusso, Francesco Raspagliesi
STUDY OBJECTIVE: Growing evidence supports the safety of a laparoscopic approach for patients affected by apparent early-stage ovarian cancer. However, no well-designed studies comparing laparoscopic and open surgical staging are available. In the present investigation we aimed to provide a balanced long-term comparison between these 2 approaches. DESIGN: Retrospective study (Canadian Task Force classification II-2). SETTING: Tertiary center...
January 1, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27692668/intraperitoneal-chemotherapy-after-interval-debulking-surgery-for-advanced-stage-ovarian-cancer-feasibility-and-outcomes-at-a-comprehensive-cancer-center
#20
Jennifer J Mueller, Amelia Kelly, Qin Zhou, Alexia Iasonos, Kara Long Roche, Yukio Sonoda, Roisin E O'Cearbhaill, Oliver Zivanovic, Dennis S Chi, Ginger J Gardner
OBJECTIVES: Intraperitoneal (IP)-based chemotherapy following primary debulking surgery (PDS), although associated with substantial toxicity, is supported by a strong evidence base. We sought to determine feasibility and outcomes of IP chemotherapy after interval debulking surgery (IDS) among patients deemed ineligible for PDS. METHODS: We identified all patients with high-grade, stage III/IV ovarian cancer treated at our institution with neoadjuvant chemotherapy (NACT) followed by IDS and postoperative chemotherapy from 1/2008-5/2013...
December 2016: Gynecologic Oncology
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