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https://www.readbyqxmd.com/read/27865612/changes-in-intestinal-immunity-gut-microbiota-and-expression-of-energy-metabolism-related-genes-explain-adenoma-growth-in-bilberry-and-cloudberry-fed-apc-min-mice
#1
Essi Päivärinta, Mikael Niku, Johanna Maukonen, Markus Storvik, Anu Heiman-Lindh, Maria Saarela, Anne-Maria Pajari, Marja Mutanen
We showed previously that ellagitannin-rich cloudberries and anthocyanin-rich bilberries reduce the number of intestinal adenomas in multiple intestinal neoplasia/+ (Apc(Min)) mice. We also found that cloudberries decreased the size of adenomas, whereas bilberries increased it. Here we hypothesized that the difference in adenoma growth could be explained by dissimilar effects of the berries on intestinal immune responses and gut microbiota, potentially driven by the distinct polyphenol compositions of the 2 berries...
October 15, 2016: Nutrition Research
https://www.readbyqxmd.com/read/27855899/phenolic-compounds-extracted-by-acidic-aqueous-ethanol-from-berries-and-leaves-of-different-berry-plants
#2
Ye Tian, Jaana Liimatainen, Aino-Liisa Alanne, Anni Lindstedt, Pengzhan Liu, Jari Sinkkonen, Heikki Kallio, Baoru Yang
Phenolic compounds of berries and leaves of thirteen various plant species were extracted with aqueous ethanol and analyzed with UPLC-DAD-ESI-MS, HPLC-DAD, and NMR. The total content of phenolics was consistently higher in leaves than in berries (25-7856 vs. 28-711mg/100g fresh weight). Sea buckthorn leaves were richest in phenolic compounds (7856mg/100g f.w.) with ellagitannins as the dominant compound class. Sea buckthorn berries contained mostly isorhamnetin glycosides, whereas quercetin glycosides were typically abundant in most samples investigated...
April 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27755647/effect-of-oak-chips-on-evolution-of-phenolic-compounds-and-color-attributes-of-bog-bilberry-syrup-wine-during-bottle-aging
#3
Shuxun Liu, Shaoyang Wang, Guanshen Yuan, Xiaoyu Ouyang, Yaran Liu, Baoqing Zhu, Bolin Zhang
This study investigated the evolution of phenolic compounds of bog bilberry syrup wine during a bottle-aging process, and further estimated the oak chip treatment on the wine color alteration. The wine was macerated with oak chips (2 or 5 g/L under light or medium toasting level) for 20 d and then bottle-aged for 6 mo. Results showed that the oak chip treatment significantly increased the content of phenolic compounds and enhanced the copigmented anthocyanin level before aging. It also resulted in an increase on a(*) and C(*) but a decrease on L(*) , b(*) , and H(*) of the wine...
October 18, 2016: Journal of Food Science
https://www.readbyqxmd.com/read/27748191/a-brief-review-of-blue-and-bilberries-potential-to-curb-cardio-metabolic-perturbations-focus-on-diabetes
#4
M Carmen Crespo, Francesco Visioli
Some epidemiological studies suggest that increased consumption of anthocyanins is associated with lower risk of cardiovascular disease (CVD) and hypertension. Also, high consumption of anthocyanin-rich fruit, such as berries, is associated with a lower risk of developing type 2 diabetes (T2D). In this review, we briefly yet critically assess the available evidence in support of an anti-diabetic role of anthocyanins derived from berries, especially bilberry (Vaccinium myrtillus L., also known as European blueberry, whortleberry, huckleberry and blaeberry) and blueberry (Vaccinium corymbosum, native to the United States)...
October 10, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27747228/black-currant-ribes-nigrum-l-and-bilberry-vaccinium-myrtillus-l-fruit-juices-inhibit-adhesion-of-asaia-spp
#5
Hubert Antolak, Agata Czyzowska, Dorota Kregiel
The aim of the study was to evaluate the activity of high-polyphenolic black currant (Ribes nigrum L.) and bilberry (Vaccinium myrtillus L.) juices against bacterial strains Asaia lannensis and Asaia bogorensis isolated as spoilage of commercial soft drinks. The composition of fruit juices was evaluated using chromatographic techniques HPLC and LC-MS. The adhesion to glass, polystyrene, and polyethylene terephthalate in two different culture media was evaluated by luminometry and the plate count method. The major anthocyanins in the V...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27714928/bilberry-chemical-profiling-in-vitro-and-in-vivo-antioxidant-activity-and-nephroprotective-effect-against-gentamicin-toxicity-in-rats
#6
Milica Veljković, Dragana R Pavlović, Nenad Stojiljković, Sonja Ilić, Ivan Jovanović, Nataša Poklar Ulrih, Violeta Rakić, Ljubinka Veličković, Dušan Sokolović
We assessed possible protective effect of bilberry diet in rat model of nephrotoxicity. In vivo and in vitro antioxidant activity and chemical profiling of this functional food was performed. With aid of HPLC-DAD and spectrophotometric method, 15 individual anthocyanins were quantified alongside total tannin, phenylpropanoid, and anthocyanin content. The study was conducted on four groups of rats: control, treated with only gentamicin, treated with only bilberry, and treated with both gentamicin and bilberry...
October 6, 2016: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/27704523/the-effect-of-bilberries-on-diabetes-related-alterations-of-interstitial-cells-of-cajal-in-the-lower-oesophageal-sphincter-in-rats
#7
Aleksandra Velickov, Olivera Mitrovic, Branka Djordjevic, Dusan Sokolovic, Vladimir Zivkovic, Asen Velickov, Vukica Pantovic, Natasa Poklar Urlih, Goran Radenkovic
Diabetic gastroenteropathy involves not only the parasympathetic and sympathetic autonomic nerves, but also enteric neurons, smooth muscle cells and interstitial cells of Cajal (ICC). ICC are the cells of mesenchymal origin that occur within and around the muscle layers in the gastrointestinal tract. The objective of the present study was to investigate the alterations of ICC in the lower oesophageal sphincter (LOS) of streptozotocin-nicotinamide non-insulin-dependent diabetes rats. Moreover, we investigated possible ICC in rats with the same type of diabetes, treated with bilberry fruit extract, bearing in mind that its hypoglycemic effect had been already proven...
October 5, 2016: Histology and Histopathology
https://www.readbyqxmd.com/read/27696003/temporal-effects-of-hunting-on-foraging-behavior-of-an-apex-predator-do-bears-forego-foraging-when-risk-is-high
#8
Anne G Hertel, Andreas Zedrosser, Atle Mysterud, Ole-Gunnar Støen, Sam M J G Steyaert, Jon E Swenson
Avoiding predators most often entails a food cost. For the Scandinavian brown bear (Ursus arctos), the hunting season coincides with the period of hyperphagia. Hunting mortality risk is not uniformly distributed throughout the day, but peaks in the early morning hours. As bears must increase mass for winter survival, they should be sensitive to temporal allocation of antipredator responses to periods of highest risk. We expected bears to reduce foraging activity at the expense of food intake in the morning hours when risk was high, but not in the afternoon, when risk was low...
December 2016: Oecologia
https://www.readbyqxmd.com/read/27625778/anthocyanin-analyses-of-vaccinium-fruit-dietary-supplements
#9
Jungmin Lee
Vaccinium fruit ingredients within dietary supplements were identified by comparisons with anthocyanin analyses of known Vaccinium profiles (demonstration of anthocyanin fingerprinting). Available Vaccinium supplements were purchased and analyzed, their anthocyanin profiles (based on high-performance liquid chromatography [HPLC] separation) indicated if products' fruit origin listings were authentic. Over 30% of the Vaccinium fruit (cranberry, lingonberry, bilberry, and blueberry; 14 of 45) products available as dietary supplements did not contain the fruit listed as ingredients...
September 2016: Food Science & Nutrition
https://www.readbyqxmd.com/read/27496184/multiplicity-of-effects-and-health-benefits-of-resveratrol
#10
REVIEW
Lolita Kuršvietienė, Inga Stanevičienė, Aušra Mongirdienė, Jurga Bernatonienė
Resveratrol is mainly found in grapes and red wine, also in some plants and fruits, such as peanuts, cranberries, pistachios, blueberries and bilberries. Moreover, nowadays this compound is available as purified preparation and dietary supplement. Resveratrol provides a wide range of benefits, including cardiovascular protective, antiplatelet, antioxidant, anti-inflammatory, blood glucose-lowering and anticancer activities, hence it exhibits a complex mode of action. During the recent years, these properties have been widely studied in animal and human models, both in vitro and in vivo...
2016: Medicina
https://www.readbyqxmd.com/read/27485636/bilberry-extract-its-major-polyphenolic-compounds-and-the-soy-isoflavone-genistein-antagonize-the-cytostatic-drug-erlotinib-in-human-epithelial-cells
#11
G Aichinger, G Pahlke, L J Nagel, W Berger, D Marko
Erlotinib (Tarceva®) is a chemotherapeutic drug approved for the treatment of pancreatic cancer and non-small cell lung cancer. Its primary mode of action is the inhibition of the epidermal growth factor receptor (EGFR), a receptor tyrosine kinase (RTK). Recently, RTK-inhibiting polyphenols have been reported to interact synergistically with erlotinib. Furthermore some anthocyanidins and anthocyanin-rich berry extracts have been reported to inhibit tyrosine kinases, including the EGFR, which raises the question of potential interactions with erlotinib...
August 10, 2016: Food & Function
https://www.readbyqxmd.com/read/27451155/seasonal-variations-of-the-phenolic-constituents-in-bilberry-vaccinium-myrtillus-l-leaves-stems-and-fruits-and-their-antioxidant-activity
#12
Oana-Crina Bujor, Carine Le Bourvellec, Irina Volf, Valentin I Popa, Claire Dufour
The seasonal variations of the content and diversity of phenolic compounds, as well as the antioxidant activity of leaves, stems and fruits of bilberry collected in May, July and September, were evaluated for two consecutive years. UPLC/MS(n) analyses showed the predominance of anthocyanins in fruits, caffeic acid derivatives in leaves whereas flavanol oligomers represented more than half of the phenolic compounds in stems. Thioacidolysis revealed degrees of polymerization between 2 and 4 and (-)-epicatechin as the main flavanol unit...
December 15, 2016: Food Chemistry
https://www.readbyqxmd.com/read/27365896/effects-of-anthocyanin-and-flavanol-compounds-on-lipid-metabolism-and-adipose-tissue-associated-systemic-inflammation-in-diet-induced-obesity
#13
Roel A van der Heijden, Martine C Morrison, Fareeba Sheedfar, Petra Mulder, Marijke Schreurs, Pascal P H Hommelberg, Marten H Hofker, Casper Schalkwijk, Robert Kleemann, Uwe J F Tietge, Debby P Y Koonen, Peter Heeringa
Background. Naturally occurring substances from the flavanol and anthocyanin family of polyphenols have been proposed to exert beneficial effects in the course of obesity. We hypothesized that their effects on attenuating obesity-induced dyslipidemia as well as the associated inflammatory sequelae especially have health-promoting potential. Methods. Male C57BL/6J mice (n = 52) received a control low-fat diet (LFD; 10 kcal% fat) for 6 weeks followed by 24 weeks of either LFD (n = 13) or high-fat diet (HFD; 45 kcal% fat; n = 13) or HFD supplemented with 0...
2016: Mediators of Inflammation
https://www.readbyqxmd.com/read/27338070/bilberry-extracts-are-not-created-equal-the-role-of-non-anthocyanin-fraction-discovering-the-dark-side-of-the-force-in-a-preliminary-study
#14
C Gizzi, G Belcaro, G Gizzi, B Feragalli, M Dugall, R Luzzi, U Cornelli
OBJECTIVE: Several experimental studies and clinical trials support the potential of bilberry (Vaccinium myrtillus L) extracts in promoting eye health and circulation. Many active ingredients have been isolated from the berries and leaves of the bilberry plant. However, anthocyanins represent the most widely studied bioactive compounds in this plant. PATIENTS AND METHODS: The aim of this registry, supplement study was to evaluate the effects of Mirtoselect® (standardized in 36% anthocyanins and obtained by an industrial extraction process that preserves the full range of the non-anthocyanin components, mainly natural sugars and polyphenols) in different types of retinal vasculopathies...
June 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27312419/antioxidant-and-proapoptotic-effects-of-anthocyanins-from-bilberry-extract-in-rats-exposed-to-hepatotoxic-effects-of-carbon-tetrachloride
#15
Dejan Popović, Davor Đukić, Vukica Katić, Zorica Jović, Maja Jović, Jelena Lalić, Ilija Golubović, Svetlana Stojanović, Nataša Poklar Ulrih, Marko Stanković, Dušan Sokolović
AIMS: The aim of this research was to determine the hepatoprotective effects of anthocyanins from bilberry extract in rats exposed to carbon tetrachloride (CCl4) by monitoring the parameters of oxidative stress and apoptosis, and by performing the histopathological and morphometric analyses. MAIN METHODS: Animals were divided into four groups: Group I (0.9% NaCl-10days), Group II (bilberry extract, 75mg/kg-10days), Group III (0,9% NaCl-9days, and on the tenth day CCl4-2ml/kg), Group IV (bilberry extract, 75mg/kg-10days and on the tenth day CCl4-2ml/kg)...
July 15, 2016: Life Sciences
https://www.readbyqxmd.com/read/27283708/white-versus-blue-does-the-wild-albino-bilberry-vaccinium-myrtillus-l-differ-in-fruit-quality-compared-to-the-blue-one
#16
Zala Zorenc, Robert Veberic, Franci Stampar, Darinka Koron, Maja Mikulic-Petkovsek
Wild albino and blue bilberry fruit were analyzed to compare different fruit characteristics linked to the composition of primary and secondary metabolites. Compounds were identified using HPLC-MS and standard quality parameters were determined. Albino berries were significantly smaller, accumulated less water and were characterized by 23% higher dry weight. Soluble solids content and pH value were higher in albino bilberry and their surface was lighter and characterized by a yellow hue. Both bilberry forms accumulated identical individual sugars and organic acids; however, the albino form had 33% higher content of total sugars and 9% higher content of total organic acids compared to the blue type...
November 15, 2016: Food Chemistry
https://www.readbyqxmd.com/read/27258314/berry-leaves-an-alternative-source-of-bioactive-natural-products-of-nutritional-and-medicinal-value
#17
REVIEW
Anastasia-Varvara Ferlemi, Fotini N Lamari
Berry fruits are recognized, worldwide, as "superfoods" due to the high content of bioactive natural products and the health benefits deriving from their consumption. Berry leaves are byproducts of berry cultivation; their traditional therapeutic use against several diseases, such as the common cold, inflammation, diabetes, and ocular dysfunction, has been almost forgotten nowadays. Nevertheless, the scientific interest regarding the leaf composition and beneficial properties grows, documenting that berry leaves may be considered an alternative source of bioactives...
2016: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/27242856/on-the-developmental-and-environmental-regulation-of-secondary-metabolism-in-vaccinium-spp-berries
#18
REVIEW
Katja Karppinen, Laura Zoratti, Nga Nguyenquynh, Hely Häggman, Laura Jaakola
Secondary metabolites have important defense and signaling roles, and they contribute to the overall quality of developing and ripening fruits. Blueberries, bilberries, cranberries, and other Vaccinium berries are fleshy berry fruits recognized for the high levels of bioactive compounds, especially anthocyanin pigments. Besides anthocyanins and other products of the phenylpropanoid and flavonoid pathways, these berries also contain other metabolites of interest, such as carotenoid derivatives, vitamins and flavor compounds...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27217612/bears-and-berries-species-specific-selective-foraging-on-a-patchily-distributed-food-resource-in-a-human-altered-landscape
#19
Anne G Hertel, Sam M J G Steyaert, Andreas Zedrosser, Atle Mysterud, Hanna K Lodberg-Holm, Henriette Wathne Gelink, Jonas Kindberg, Jon E Swenson
ABSTRACT: When animals are faced with extraordinary energy-consuming events, like hibernation, finding abundant, energy-rich food resources becomes particularly important. The profitability of food resources can vary spatially, depending on occurrence, quality, and local abundance. Here, we used the brown bear (Ursus arctos) as a model species to quantify selective foraging on berries in different habitats during hyperphagia in autumn prior to hibernation. During the peak berry season in August and September, we sampled berry occurrence, abundance, and sugar content, a proxy for quality, at locations selected by bears for foraging and at random locations in the landscape...
2016: Behavioral Ecology and Sociobiology
https://www.readbyqxmd.com/read/27185113/interaction-between-%C3%AE%C2%BA-and-%C3%AE-carrageenan-and-anthocyanins-from-vaccinium-myrtillus
#20
Vesta Navikaite, Deimante Simanaviciute, Rima Klimaviciute, Valdas Jakstas, Liudas Ivanauskas
Anthocyanins (ATCs) from the Vaccinium myrtillus water extract have been incorporated into the κ-carrageenan (κ-CARG) or ι-carrageenan (ι-CARG) during complexation in dilute solutions or adsorption onto the microgranules of κ-CARG or ι-CARG cross-linked with epichlorohydrin. At the optimal weight ratio of CARG to ATC at 0.4:1 and the total ATCs and CARG concentration≤0.07g/L, stable dispersions of the κ-CARG/ATCs or ι-CARG/ATCs complex nanosize particles were obtained. The Langmuir, Freundlich and Dubinin-Radushkevich adsorption models have been used to describe the equilibrium adsorption of ATCs on cross-linked CARG...
September 5, 2016: Carbohydrate Polymers
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