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https://www.readbyqxmd.com/read/29774828/bilberry-pomace-in-rabbit-nutrition-effects-on-growth-performance-apparent-digestibility-caecal-traits-bacterial-community-and-antioxidant-status
#1
S Dabbou, I Ferrocino, A Kovitvadhi, S Bergagna, D Dezzuto, A Schiavone, L Cocolin, F Gai, V Santoro, L Gasco
Agricultural by-products could be used as alternative raw materials in rabbit nutrition as they have been found to be highly nutritious and low cost feeding sources. The aim of this study was to estimate the nutritive value and potential use of bilberry pomace (BP) for growing rabbits. A total of 144 Grimaud rabbits (35 days old) were allotted to four groups and fed with a diet containing increasing level of BP: BP0 (basal diet), BP5, BP10 and BP15 containing 0, 50, 100 and 150 g/kg respectively. Growth trial lasted 48 days; apparent digestibility was evaluated, starting at 46 days of age, over 4 consecutive days...
May 18, 2018: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29743826/effect-of-bilberry-juice-on-indices-of-muscle-damage-and-inflammation-in-runners-completing-a-half-marathon-a-randomised-placebo-controlled-trial
#2
Anthony Lynn, Samantha Garner, Nichola Nelson, Trevor N Simper, Anna C Hall, Mayur K Ranchordas
Background: Emerging evidence indicates that fruits rich in polyphenols may attenuate exercise-induced muscle damage and associated markers of inflammation and soreness. This study was conducted to determine whether bilberry juice (BJ), which is particularly rich in polyphenols, reduces markers of muscle damage in runners completing a half marathon. Methods: A total of 21 recreationally trained runners (age 30.9 ± 10.4 y; mass 71.6 ± 11.0 kg; M = 16; F = 5) were recruited to a single blind, randomised, placebo-controlled, parallel study...
2018: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/29698464/shrub-growth-and-plant-diversity-along-an-elevation-gradient-evidence-of-indirect-effects-of-climate-on-alpine-ecosystems
#3
Francesco Boscutti, Valentino Casolo, Paola Beraldo, Enrico Braidot, Marco Zancani, Christian Rixen
Enhanced shrub growth and expansion are widespread responses to climate warming in many arctic and alpine ecosystems. Warmer temperatures and shrub expansion could cause major changes in plant community structure, affecting both species composition and diversity. To improve our understanding of the ongoing changes in plant communities in alpine tundra, we studied interrelations among climate, shrub growth, shrub cover and plant diversity, using an elevation gradient as a proxy for climate conditions. Specifically, we analyzed growth of bilberry (Vaccinium myrtillus L...
2018: PloS One
https://www.readbyqxmd.com/read/29611487/complexation-of-bioelements-and-toxic-metals-by-polyphenolic-compounds-implications-for-health
#4
Sylwia Borowska, Malgorzata Michalina Brzoska, Michal Tomczyk
Nowadays growing interest in the possibility of prophylactic and therapeutic use of plant products rich in biologically active compounds has been observed. Among them special interest has been focused on polyphenol-rich products. Owing to multidirectional favourable action of polyphenols, products rich in these compounds are recommended as functional food in the case of civilization diseases. Moreover, data from studies in animal models show that polyphenols may be a promising preventive/therapeutic strategy for xenobiotics, including toxic heavy metals...
April 2, 2018: Current Drug Targets
https://www.readbyqxmd.com/read/29549446/accumulation-and-dynamics-of-manganese-content-in-bilberry-vaccinium-myrtillus-l
#5
E Kula, E Wildová, P Hrdlička
In a specific area of the Krušné Hory Mts. (Ore Mountains), Czech Republic, branches and leaves of bilberry (Vaccinium myrtillus L.) were collected during the growing seasons in 2010-2016 on the low-pH soil (2.77-3.62) with a high total content of manganese (490-6277 mg kg-1 dwt.). Mn content in leaves occurred in a wide range (274-11,159 mg kg-1 ) and was markedly increased during the growing season with the exception of year 2015, when the leaves dried out early due to the precipitation deficit. New leaves exhibited the Mn content corresponding to the beginning of the growing season...
March 16, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29486772/probiotic-fruit-beverages-with-different-polyphenol-profiles-attenuated-early-insulin-response
#6
Jie Xu, Tommy Jönsson, Merichel Plaza, Åsa Håkansson, Martin Antonsson, Irini Lazou Ahrén, Charlotta Turner, Peter Spégel, Yvonne Granfeldt
BACKGROUND: Consumption of polyphenol-rich fruits and vegetables may improve postprandial glucose and insulin levels and hence promote well-being. Previously it has been observed that consumption of bilberry decreases the postprandial insulin demand. The intention with the present study was to compare the impact of different supplements with various polyphenol profiles, on the postprandial glucose and insulin responses in healthy young adults. METHODS: In a randomized, controlled, crossover study the postprandial glycemic and insulin responses were observed in eleven healthy adults after intake of five different beverages containing bilberry (European blueberry), blackcurrant, beetroot, mango and rose hip, respectively; all drinks were enriched with the same composition of fermented oatmeal and probiotics...
February 27, 2018: Nutrition Journal
https://www.readbyqxmd.com/read/29435281/effect-of-anthocyanin-rich-bilberry-extract-on-bone-metabolism-in-ovariectomized-rats
#7
Saki Shimizu, Hiroshi Matsushita, Yuko Morii, Yuriko Ohyama, Noriko Morita, Rika Tachibana, Kazushi Watanabe, Akihiko Wakatsuki
Menopause is associated with increased oxidative stress, which serves a role, in part, in the pathogenesis of postmenopausal bone loss. Fruits and vegetables are rich in antioxidative nutrients and phytochemicals. Berries are a natural source of anthocyanins, and their intake may improve bone health. The aim of the present study was to determine the effect of an anthocyanin-rich bilberry extract (VME) on bone metabolism in an ovariectomized (Ovx) rat. Female Sprague-Dawley rats (12 weeks old) were randomly divided into the following four groups: Baseline, Sham, Ovx and Ovx+VME (n=8-12 rats per group)...
February 2018: Biomedical Reports
https://www.readbyqxmd.com/read/29428993/high-performance-liquid-chromatography-for-the-analytical-characterization-of-anthocyanins-in-vaccinium-myrtillus-l-bilberry-fruit-and-food-products
#8
Stefania Benvenuti, Virginia Brighenti, Federica Pellati
Anthocyanins represent the most abundant class of bioactive compounds present in Vaccinium myrtillus L. (bilberry) fruit, conferring it several health-promoting properties. The content of anthocyanins in food products produced from bilberries can be affected by many parameters, making the study of their composition a critical issue. In this ambit, this work was aimed at a comprehensive profiling of anthocyanins in bilberry fruit and derivatives from the Italian Northern Apennines, including jam, juice, and liqueur ("Mirtillino")...
February 10, 2018: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29399357/anticancer-effects-of-bilberry-anthocyanins-compared-with-nutrananosphere-encapsulated-bilberry-anthocyanins
#9
Seth P Thibado, Jerry T Thornthwaite, Thomas K Ballard, Brandon T Goodman
Rapidly accumulating laboratory and clinical research evidence indicates that anthocyanins exhibit anticancer activity and the evaluation of bilberry anthocyanins as chemo-preventive agents is progressing. It has previously been demonstrated that anthocyanins upregulate tumor suppressor genes, induce apoptosis in cancer cells, repair and protect genomic DNA integrity, which is important in reducing age-associated oxidative stress, and improve neuronal and cognitive brain function. Bilberry anthocyanins have pronounced health effects, even though they have a low bioavailability...
February 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29335694/the-seventh-biennial-berry-health-benefits-symposium
#10
EDITORIAL
Navindra P Seeram, Britt Burton-Freeman
Research advancing current scientific understanding of the health benefits of berries continues to increase. The Berry Health Benefits Symposium (BHBS) is a biennial meeting highlighting the most recent berry health benefits research from all over the world. Pismo Beach, California was the venue for the seventh biennial BHBS in 2017, and featured oral invited papers on heart health and healthy aging, gut/microbiome health, brain aging, inflammation, cancer prevention, berry special topics, technology and chemistry...
January 24, 2018: Food & Function
https://www.readbyqxmd.com/read/29329847/encapsulation-of-anthocyanins-from-bilberries-effects-on-bioavailability-and-intestinal-accessibility-in-humans
#11
Dolores Mueller, Kathrin Jung, Manuel Winter, Dorothee Rogoll, Ralph Melcher, Ulrich Kulozik, Karin Schwarz, Elke Richling
Anthocyanins are flavonoids that have been suggested to provide beneficial health effects. The biological activity of anthocyanins is influenced by their pharmacokinetic properties, but anthocyanins are associated with limited bioavailability in humans. In the presented study, we investigated how the encapsulation of bilberry extract (BE), a source of anthocyanins, with either whey protein or citrus pectin influences the bioavailability and intestinal accessibility of anthocyanins in humans. We performed an intervention study that analyzed anthocyanins and their degradation products in the urine, plasma, and ileal effluent of healthy volunteers and ileostomists (subjects without an intact colon)...
May 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29297598/visualization-of-the-distribution-of-anthocyanin-species-in-mice-eyeball-by-matrix-assisted-laser-desorption-ionization-mass-spectrometry-imaging
#12
Shuhei Yamada, Nobuhiro Zaima, Yukihiro Yoshimura, Shiori Inaba, Takamichi Fujimori, Tetsuya Sogon, Tatsuya Moriyama
RATIONALE: Anthocyanins, which belong to a class of molecules called flavonoids, are known to have beneficial effects for both humans and animals. Many physiological functions have been attributed to anthocyanins since ancient times. The most important function is the relief of eyestrain, but the biodistribution of anthocyanins remains unknown. In this study, we analyzed the kinetics of anthocyanin species in mice eyeballs and surrounding tissues. METHODS: We used mice that were administered bilberry extract solution intraperitoneally...
March 15, 2018: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/29182628/inhibitory-activity-of-chokeberry-bilberry-raspberry-and-cranberry-polyphenol-rich-extract-towards-adipogenesis-and-oxidative-stress-in-differentiated-3t3-l1-adipose-cells
#13
Katarzyna Kowalska, Anna Olejnik, Dominik Szwajgier, Mariola Olkowicz
Berries are a rich source of antioxidants and phytochemicals that have received considerable interest for their possible relations to human health. In this study, the anti-adipogenic effect of polyphenol-rich extract obtained from chokeberry Aronia melanocarpa (Michx.) Elliot, raspberry Rubus idaeus L., bilberry Vaccinium myrtillus L. and cranberry Vaccinium macrocarpon Aiton fruits and its underlying molecular mechanisms were investigated in differentiated 3T3-L1 adipose cells. Treatment with the extract (25-100 μg/mL) significantly decreased lipid accumulation and reactive oxygen species generation in adipocytes without showing cytotoxicity...
2017: PloS One
https://www.readbyqxmd.com/read/29131240/mirtogenol%C3%A2-supplementation-in-association-with-dorzolamide-timolol-or-latanoprost-improves-the-retinal-microcirculation-in-asymptomatic-patients-with-increased-ocular-pressure
#14
C Gizzi, P Torino-Rodriguez, G Belcaro, S Hu, M Hosoi, B Feragalli
OBJECTIVE: Supplementation with Mirtogenol® improves the retinal microcirculation and reduces intraocular pressure (IOP) in ocular hypertension, when administrated either alone or in association with an ophthalmic solution (latanoprost). In this study, microcirculatory parameters (perfusion of the circle of Zinn-Haller and retinal circulation) and oxidative stress were tested to assess the effects of Mirtogenol® plus traditional antihypertensive drugs in patients with elevated IOP. PATIENTS AND METHODS: 88 otherwise healthy patients with increased IOP were followed-up in a supplement registry for 12 weeks...
October 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29104724/protective-effects-of-oral-astaxanthin-nanopowder-against-ultraviolet-induced-photokeratitis-in-mice
#15
Fumiya Harada, Tetsuro Morikawa, Anton Lennikov, Anthony Mukwaya, Mira Schaupper, Osamu Uehara, Rie Takai, Koki Yoshida, Jun Sato, Yukihiro Horie, Hiroyuki Sakaguchi, Ching-Zong Wu, Yoshihiro Abiko, Neil Lagali, Nobuyoshi Kitaichi
Purpose: Astaxanthin (AST) has a strong antioxidant cellular membrane chaperone protective effect. Recently, a water-soluble nanosized AST (nano-AST) form was produced, which is expected to improve the efficacy of oral intake effects. The purpose of this study was to examine whether oral nano-AST has therapeutic effects on UV-induced photokeratitis in mice. Methods: C57BL/6 mice were administered twice with either nano-AST, AST oil, lutein, or bilberry extracts 3 hours before and shortly before UV irradiation (dose: 400 mJ/cm2 )...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29066860/bilberry-extract-administration-prevents-retinal-ganglion-cell-death-in-mice-via-the-regulation-of-chaperone-molecules-under-conditions-of-endoplasmic-reticulum-stress
#16
Orie Nakamura, Satoru Moritoh, Kota Sato, Shigeto Maekawa, Namie Murayama, Noriko Himori, Kazuko Omodaka, Tetsuya Sogon, Toru Nakazawa
PURPOSE: To investigate the effect of bilberry extract anthocyanins on retinal ganglion cell (RGC) survival after optic nerve crush. Additionally, to determine details of the mechanism of the neuroprotective effect of bilberry extract anthocyanins and the involvement of endoplasmic reticulum stress suppression in the mouse retina. MATERIALS AND METHODS: Anthocyanins in bilberry extract (100 mg/kg/day or 500 mg/kg/day) were administrated orally to C57BL/6J mice. The expression levels of various molecular chaperones were assessed with quantitative reverse-transcription polymerase chain reaction, Western blotting, and immunohistochemistry...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28964369/profiling-of-iridoid-glycosides-in-vaccinium-species-by-uhplc-ms
#17
Peter Heffels, Laura Müller, Andreas Schieber, Fabian Weber
The iridoid profile of four Vaccinium species was investigated using UHPLC-MS to obtain further information about this group of species for phytochemical characterization. Fruits of bog bilberry (Vaccinium uliginosum L.) showed 14 different iridoid glycosides with a total amount of 20mg/kg fresh weight (FW), whereas bilberry (Vaccinium myrtillus L.) contained 11 iridoid glycosides and a total amount of 127mg/kg FW. Highbush blueberry (Vaccinium corymbosum L.) and lowbush blueberry (Vaccinium angustifolium L...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28918484/drug-herb-interactions-in-the-elderly-patient-with-ibd-a-growing-concern
#18
REVIEW
Haider Rahman, Marina Kim, Galen Leung, Jesse A Green, Seymour Katz
Inflammatory bowel disease (IBD), which includes conditions such as Crohn's disease and ulcerative colitis, is becoming more prevalent with the elderly being the fastest growing group. Parallel to this, there is an increasing interest in the use of complementary and alternative medicine (CAM). Nearly half of patients with IBD have used CAM at one time. The elderly patients, however, are burdened by comorbid conditions, polypharmacy, and altered functional status. With increasing use of complementary and alternative medicine in our elderly patients with IBD, it is vital for the provider to provide counsel on drug-herb potential interactions...
December 2017: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/28865231/effect-of-feeding-with-bilberry-fruit-on-the-expression-pattern-of-%C3%AE-camkii-in-hippocampal-neurons-in-normal-and-diabetic-rats
#19
M Matysek, S Mozel, R Szalak, A Zacharko-Siembida, K Obszańska, M B Arciszewski
αCaMKII, widely occurring in the central nervous system, plays a significant role in cognitive processes. It is well known that diabetes is a risk factor that may trigger brain atrophy, cognitive dysfunction and finally lead to memory loss. Antioxidants richly present in bilberry fruits are believed to have significant effects on diabetes-related brain dysfunctions mainly due to their abilities to modulate neurotransmitter release that lead to reduction of the negative impact of free radicals on cognitive processes...
March 1, 2017: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28804235/management-of-varicose-veins-and-chronic-venous-insufficiency-in-a-comparative-registry-with-nine-venoactive-products-in-comparison-with-stockings
#20
G Belcaro, M Dugall, R Luzzi, M Corsi, A Ledda, A Ricci, L Pellegrini, M R Cesarone, M Hosoi, B M Errichi, U Cornelli, R Cotellese, G Agus, B Feragalli
The aim of this registry study was to compare products used to control symptoms of CVI. Endpoints of the study were microcirculation, effects on volume changes, and symptoms (analogue scale). Pycnogenol, venoruton, troxerutin, the complex diosmin-hesperidin, Antistax, Mirtoselect (bilberry), escin, and the combination Venoruton-Pycnogenol (VE-PY) were compared with compressions. No safety or tolerability problems were observed. At inclusion, measurements in the groups were comparable: 1,051 patients completed the registry...
September 2017: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
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