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https://www.readbyqxmd.com/read/29122150/moving-towards-wellness-physical-activity-practices-perspectives-and-preferences-of-users-of-outpatient-mental-health-service
#1
Carol A Janney, Kathryn Fant Brzoznowski, Caroline R Richardson, Richard R Dopp, Michelle L Segar, Dara Ganoczy, Ann J Mooney, Lauren Emerson, Marcia Valenstein
OBJECTIVE: This study assessed the beliefs, barriers and preferences for physical activity (PA) among users of outpatient mental health (MH) services. Outpatient discussions with MH providers were also evaluated. METHOD: Between September-December 2014, patient advisors approached adult and family members in an academic MH clinic's waiting room on high volume patient visit days during peak clinic hours; 83% participated in the survey. Analyses were restricted to MH services users (n=295)...
November 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/29121874/evaluating-the-effectiveness-of-iv-iron-dosing-for-anemia-management-in-common-clinical-practice-results-from-the-dialysis-outcomes-and-practice-patterns-study-dopps
#2
Bruce M Robinson, Maria Larkina, Brian Bieber, Werner Kleophas, Yun Li, Francesco Locatelli, Keith P McCullough, Jackie G Nolen, Friedrich K Port, Ronald L Pisoni
BACKGROUND: Anemia management protocols in hemodialysis (HD) units differ conspicuously regarding optimal intravenous (IV) iron dosing; consequently, patients receive markedly different cumulative exposures to IV iron and erythropoiesis-stimulating agents (ESAs). Complementary to IV iron safety studies, our goal was to gain insight into optimal IV iron dosing by estimating the effects of IV iron doses on Hgb, TSAT, ferritin, and ESA dose in common clinical practice. METHODS: 9,471 HD patients (11 countries, 2009-2011) in the DOPPS, a prospective cohort study, were analyzed...
November 9, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/29040687/mortality-risk-in-patients-on-hemodiafiltration-versus-hemodialysis-a-real-world-comparison-from-the-dopps
#3
Francesco Locatelli, Angelo Karaboyas, Ronald L Pisoni, Bruce M Robinson, Joan Fort, Raymond Vanholder, Hugh C Rayner, Werner Kleophas, Stefan H Jacobson, Christian Combe, Friedrich K Port, Francesca Tentori
Background: With its convective component, hemodiafiltration (HDF) provides better middle molecule clearance compared with hemodialysis (HD) and is postulated to improve survival. A previous analysis of Dialysis Outcomes and Practice Patterns Study (DOPPS) data in 1998-2001 found lower mortality rates for high replacement fluid volume HDF versus HD. Randomized controlled trials have not shown uniform survival advantage for HDF; in secondary (non-randomized) analyses, better outcomes were observed in patients receiving the highest convection volumes...
October 11, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28941772/influence-of-the-copper-induced-viable-but-non-culturable-state-on-the-toxicity-of-pseudomonas-aeruginosa-towards-human-bronchial-epithelial-cells-in-vitro
#4
Elke Dopp, Jessica Richard, Zenyta Dwidjosiswojo, Anne Simon, Jost Wingender
The viable but non-culturable (VBNC) state of the opportunistic bacterium Pseudomonas aeruginosa was previously shown to be induced by copper ions in concentrations relevant to those in drinking water plumbing systems. This decrease of bacterial culturability without loss of viability might have an influence on human health due to an underestimation of the actual contamination in drinking water systems. The aim of this study was to investigate the influence of culturable P. aeruginosa, viable but not culturable as well as culturable again after resuscitation from the VBNC state on human bronchial epithelial cells (BEAS-2B) in vitro...
November 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28880814/investigation-of-full-scale-ozonation-at-a-municipal-wastewater-treatment-plant-using-a-toxicity-based-evaluation-concept
#5
Fabian Itzel, Linda Gehrmann, Helena Bielak, Paul Ebersbach, Andrea Boergers, Heinrich Herbst, Christian Maus, Anne Simon, Elke Dopp, Monika Hammers-Wirtz, Torsten C Schmidt, Jochen Tuerk
Effluents from municipal wastewater treatment plants (WWTPs) are known to be point sources of micropollutants for surface waters. The aim of this study was to examine a reconstructed full-scale ozonation equipped with a pump-injector system for ozone (O3) dosage and a fluidized moving-bed reactor as biological posttreatment at a municipal WWTP utilizing an effect-directed approach. This approach consists of chemical analysis in combination with toxicological tests for the assessment of treatment efficiency of the plant...
September 7, 2017: Journal of Toxicology and Environmental Health. Part A
https://www.readbyqxmd.com/read/28877202/shorter-dialysis-session-length-was-not-associated-with-lower-mental-health-and-physical-functioning-in-elderly-hemodialysis-patients-results-from-the-japan-dialysis-outcome-and-practice-patterns-study-j-dopps
#6
Masashi Kitagawa, Ken-Ei Sada, Norikazu Hinamoto, Miho Kimachi, Yosuke Yamamoto, Yoshihiro Onishi, Shunichi Fukuhara
BACKGROUND: Health-related quality of life (HRQOL) is often prioritized over long-term survival in elderly patients. Although a longer dialysis session length (DSL) has been shown to reduce mortality, its effects on improving the HRQOL are unknown. METHODS: Using data from the Japan Dialysis Outcomes and Practice Patterns Study (J-DOPPS), patients aged ≥ 65 years on maintenance hemodialysis were enrolled. DSL was categorized as short (<210 minutes), medium (210-240 minutes), or long (>240 minutes)...
2017: PloS One
https://www.readbyqxmd.com/read/28834360/ras-inhibitor-is-not-associated-with-cardiovascular-benefits-in-patients-undergoing-hemodialysis-in-japan
#7
Masahide Mizobuchi, Hiroaki Ogata, Yoshihiro Onishi, Shingo Fukuma, Tadao Akizawa, Shunichi Fukuhara
Definitive evidence of whether renin angiotensin system (RAS) inhibition is beneficial on cardiovascular events (CVE) among patients undergoing hemodialysis (HD) is lacking. The objective of this study was to investigate the association of RAS inhibitor usage with CVEs in patients enrolled in the Dialysis Outcomes Practice Pattern Study in Japan (J-DOPPS). Association of RAS inhibitor prescription with outcomes including all-cause death, death caused by CVE, and hospitalization due to cardiac failure was investigated by using a multivariable Cox proportional hazards model...
August 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28771674/a-c-index-for-recurrent-event-data-application-to-hospitalizations-among-dialysis-patients
#8
Sehee Kim, Douglas E Schaubel, Keith P McCullough
We propose a C-index (index of concordance) applicable to recurrent event data. The present work addresses the dearth of measures for quantifying a regression model's ability to discriminate with respect to recurrent event risk. The data which motivated the methods arise from the Dialysis Outcomes and Practice Patterns Study (DOPPS), a long-running prospective international study of end-stage renal disease patients on hemodialysis. We derive the theoretical properties of the measure under the proportional rates model (Lin et al...
August 3, 2017: Biometrics
https://www.readbyqxmd.com/read/28742807/association-of-coping-strategies-with-mortality-and-health-related-quality-of-life-in-hemodialysis-patients-the-japan-dialysis-outcomes-and-practice-patterns-study
#9
Kakuya Niihata, Shingo Fukuma, Tadao Akizawa, Shunichi Fukuhara
BACKGROUND: Hemodialysis patients are exposed to disease- and treatment-related stresses, and use various coping strategies to deal with these stresses. Although some studies have reported the association of coping strategies with mortality or health-related quality of life (QOL) in some populations, the effect of coping strategies on clinical outcomes in hemodialysis patients remains unclear. We investigated the association in a longitudinal design among Japanese hemodialysis patients...
2017: PloS One
https://www.readbyqxmd.com/read/28724618/initiation-of-sevelamer-and-mortality-among-hemodialysis-patients-treated-with-calcium-based-phosphate-binders
#10
Hirotaka Komaba, Mia Wang, Masatomo Taniguchi, Suguru Yamamoto, Takanobu Nomura, Douglas E Schaubel, Abigail R Smith, Jarcy Zee, Angelo Karaboyas, Brian Bieber, Masafumi Fukagawa, Francesca Tentori
BACKGROUND AND OBJECTIVES: Prior studies have shown that sevelamer attenuates progression of arterial calcification and may reduce the risk of death compared with calcium-based phosphate binders. In clinical practice, however, sevelamer is used not only as an alternative but also as an add-on therapy in patients already being treated with calcium-based phosphate binders. We analyzed the Dialysis Outcomes and Practice Patterns Study (DOPPS) data to test the hypothesis that the initiation of sevelamer is associated with improved survival in patients on hemodialysis treated with calcium-based phosphate binders...
September 7, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28617161/insomnia-and-relationship-with-immunosuppressant-therapy-after-lung-transplantation
#11
Kalynn A Rohde, Zachary W Schlei, Krista M Katers, Ashley K Weber, Marissa M Brokhof, Donald S Hawes, Kelly L Radford, Mary L Francois, Nathan J Menninga, Richard Cornwell, Ruth Benca, Mary S Hayney, John M Dopp
BACKGROUND: Lung transplant recipients are at high risk of developing sleep disorders such as insomnia, but the prevalence and features are currently poorly characterized within this population. Since these disorders are associated with increased morbidity and mortality, it is important to identify them to optimize the care of lung transplant recipients. We sought to evaluate the prevalence of insomnia within our university-based lung transplant clinic and determine whether a relationship exists between insomnia and exposure to immunosuppressant medications following transplantation...
June 2017: Progress in Transplantation
https://www.readbyqxmd.com/read/28333535/family-based-treatments-for-serious-juvenile-offenders-a-multilevel-meta-analysis
#12
Alex R Dopp, Charles M Borduin, Mark H White, Sofie Kuppens
OBJECTIVE: Researchers have identified several family-based treatments that hold considerable promise in reducing serious juvenile offending; however, these treatments remain underutilized by youth service systems. In the present study, we used meta-analysis to summarize the findings of research on family-based treatments for serious juvenile offenders. METHOD: We conducted a multilevel meta-analysis that modeled dependencies between multiple effect sizes from the same study...
April 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28333534/effects-of-multisystemic-therapy-on-caregivers-of-serious-juvenile-offenders-a-20-year-follow-up-to-a-randomized-clinical-trial
#13
RANDOMIZED CONTROLLED TRIAL
Benjamin D Johnides, Charles M Borduin, David V Wagner, Alex R Dopp
OBJECTIVE: Caregivers of serious juvenile offenders often hold favorable attitudes about criminality and frequently have histories of involvement in antisocial behaviors themselves. In the present study, the authors examined the long-term criminal and noncriminal outcomes for caregivers of serious juvenile offenders who had participated two decades earlier in a randomized clinical trial of multisystemic therapy (MST; Borduin et al., 1995). METHOD: Participants were 276 caregivers of serious juvenile offenders who were originally randomized to MST or individual therapy (IT)...
April 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28332858/modified-cognitive-behavioral-therapy-for-insomnia-in-depressed-adolescents-a-pilot-study
#14
Deirdre A Conroy, Alison M Czopp, Dawn M Dore-Stites, Richard R Dopp, Roseanne Armitage, Timothy F Hoban, J Todd Arnedt
OBJECTIVE/BACKGROUND: The purpose of the study was to pilot a five-week insomnia treatment in adolescents with major depressive disorder (MDD) and insomnia. This was an open-label trial of a modified-group cognitive behavioral therapy for insomnia (CBTI). PARTICIPANTS: Adolescents with MDD (n = 16; mean age = 17.3 +/- 1.7), characterized by the Children's Depression Rating Scale-Revised T-score ≥ 55 and insomnia, characterized by > 30 min to fall or return to sleep and an Insomnia Severity Index (ISI) score of ≥ 7 participated...
March 23, 2017: Behavioral Sleep Medicine
https://www.readbyqxmd.com/read/28332306/impact-of-iatrogenic-iron-overload-on-the-course-of-hepatitis-c-in-the-dialysis-population-a-plea-for-caution
#15
REVIEW
Guy Rostoker, Nosratola D Vaziri
About 2.5% of the world population, corresponding to about 177 million individuals, are infected by hepatitis C virus (HCV), a small, single-stranded RNA virus. The prevalence of HCV infection among dialysis patients in Japan, Europe, and North America during the 2012 to 2015 period was found to be 8.7% in the DOPPS study. Nosocomial HCV spread in hemodialysis facilities still occurs. Increased hepatic tissue iron has been shown to play a deleterious role in the course of hepatitis C, favor development of fibrosis and cirrhosis and possibly increase the risk of liver cancer in the general population...
June 2017: Hemodialysis International
https://www.readbyqxmd.com/read/28320343/targets-for-adapting-intravenous-iron-dose-in-hemodialysis-a-proof-of-concept-study
#16
N O Peters, N Jay, J Cridlig, G Rostoker, L Frimat
BACKGROUND: Intravenous iron is widely used to control anemia in dialysis patients and limits costs related to erythropoiesis-stimulating agents (ESA). Current guidelines do not clearly set upper limits for serum ferritin (SF) and transferrin saturation (TSAT). International surveys such as the Dialysis Outcomes and Practice Patterns Study (DOPPS) showed that this lack of upper limits potentially led nephrologists to prescribe iron infusions even for patients with a high SF. Recent publications have suggested a risk of short- and long-term adverse effects related to iron overload...
March 20, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28299319/clinical-epidemiology-of-mineral-bone-disorder-markers-in-prevalent-hemodialysis-patients-in-the-xinjiang-uyghur-autonomous-region-in-china
#17
MULTICENTER STUDY
Ying-Ping Sun, Wen-Jun Yang, Su-Hua Li, Yuan-Yuan Han, Jian Liu
We investigated the clinical epidemiology of mineral bone disorder markers in prevalent hemodialysis (HD) patients in Xinjiang, the largest province in China. Data were obtained from 59 hospitals. A total of 3725 patients tracked from January 1 to December 31, 2014, were enrolled. Serum calcium (Ca) levels, phosphorus (P) levels, and intact parathyroid hormone (iPTH) levels were analyzed. Serum Ca levels were lower compared to the International Dialysis Outcomes and Practice Patterns Study (DOPPS4) and the Chinese DOPPS...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28285255/relationships-between-circadian-measures-depression-and-response-to-antidepressant-treatment-a-preliminary-investigation
#18
Leslie M Swanson, Helen J Burgess, Edward D Huntley, Holli Bertram, Ann Mooney, Jennifer Zollars, Richard Dopp, Robert Hoffmann, Roseanne Armitage, J Todd Arnedt
Few studies have examined relationships between circadian rhythms and unipolar major depressive disorder. Further, no study to date has examined circadian markers as predictors of response to depression treatment. In the present study, we examined associations between circadian timing and its alignment with sleep and depression severity in 30 adults with major depressive disorder who completed a randomized controlled trial of two weeks of time in bed (TIB) restriction administered adjunctive to fluoxetine, with a focus on sex differences...
June 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28273175/development-of-a-new-risk-model-for-predicting-cardiovascular-events-among-hemodialysis-patients-population-based-hemodialysis-patients-from-the-japan-dialysis-outcome-and-practice-patterns-study-j-dopps
#19
Yukiko Matsubara, Miho Kimachi, Shingo Fukuma, Yoshihiro Onishi, Shunichi Fukuhara
BACKGROUND: Cardiovascular (CV) events are the primary cause of death and becoming bedridden among hemodialysis (HD) patients. The Framingham risk score (FRS) is useful for predicting incidence of CV events in the general population, but is considerd to be unsuitable for the prediction of the incidence of CV events in HD patients, given their characteristics due to atypical relationships between conventional risk factors and outcomes. We therefore aimed to develop a new prognostic prediction model for prevention and early detection of CV events among hemodialysis patients...
2017: PloS One
https://www.readbyqxmd.com/read/28264035/associations-of-employment-status-and-educational-levels-with-mortality-and-hospitalization-in-the-dialysis-outcomes-and-practice-patterns-study-in-japan
#20
Yasuo Imanishi, Shingo Fukuma, Angelo Karaboyas, Bruce M Robinson, Ronald L Pisoni, Takanobu Nomura, Takashi Akiba, Tadao Akizawa, Kiyoshi Kurokawa, Akira Saito, Shunichi Fukuhara, Masaaki Inaba
BACKGROUND: Socioeconomic status (SES) factors such as employment, educational attainment, income, and marital status can affect the health and well-being of the general population and have been associated with the prevalence of chronic kidney disease (CKD). However, no studies to date in Japan have reported on the prognosis of patients with CKD with respect to SES. This study aimed to investigate the influences of employment and education level on mortality and hospitalization among maintenance hemodialysis (HD) patients in Japan...
2017: PloS One
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