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https://www.readbyqxmd.com/read/28432189/safety-and-efficiency-of-a-new-generic-package-labelling-a-before-and-after-study-in-a-simulated-setting
#1
Beate Hennie Garcia, Renate Elenjord, Camilla Bjornstad, Kjell Hermann Halvorsen, Sigurd Hortemo, Steinar Madsen
BACKGROUND: Medication errors are frequent and may cause harm to patients and increase healthcare expenses. AIM: To explore whether a new labelling influences time and errors when preparing medications in accordance with medication charts in an experimental setting. METHOD: We carried out an uncontrolled before and after study with 3 months inbetween experiments. Phase I used original labelling and phase II used new generic labelling. We set up an experimental medicine room, simulating a real-life setting...
April 21, 2017: BMJ Quality & Safety
https://www.readbyqxmd.com/read/28427337/treatment-seeking-behaviour-in-low-and-middle-income-countries-estimated-using-a-bayesian-model
#2
Victor A Alegana, Jim Wright, Carla Pezzulo, Andrew J Tatem, Peter M Atkinson
BACKGROUND: Seeking treatment in formal healthcare for uncomplicated infections is vital to combating disease in low- and middle-income countries (LMICs). Healthcare treatment-seeking behaviour varies within and between communities and is modified by socio-economic, demographic, and physical factors. As a result, it remains a challenge to quantify healthcare treatment-seeking behaviour using a metric that is comparable across communities. Here, we present an application for transforming individual categorical responses (actions related to fever) to a continuous probabilistic estimate of fever treatment for one country in Sub-Saharan Africa (SSA)...
April 20, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28425890/biomedical-simulation-evolution-concepts-challenges-and-future-trends
#3
Carla Sá-Couto, Luís Patrão, Francisco Maio-Matos, José Miguel Pêgo
Biomedical simulation is an effective educational complement for healthcare training, both at undergraduate and postgraduate level. It enables knowledge, skills and attitudes to be acquired in a safe, educationally orientated and efficient manner. In this context, simulation provides skills and experience that facilitate the transfer of cognitive, psychomotor and proper communication competences, thus changing behavior and attitudes, and ultimately improving patient safety. Beyond the impact on individual and team performance, simulation provides an opportunity to study organizational failures and improve system performance...
December 30, 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28420677/tcup-typing-and-characterization-of-bacteria-using-bottom-up-tandem-mass-spectrometry-proteomics
#4
Fredrik Boulund, Roger Karlsson, Lucia Gonzales-Siles, Anna Johnning, Nahid Karami, Omar Al-Bayati, Christina Ahren, Edward R B Moore, Erik Kristiansson
Methods for rapid and reliable microbial identification are essential in modern healthcare. The ability to detect and correctly identify pathogenic species and their resistance phenotype is necessary for accurate diagnosis and efficient treatment of infectious diseases. Bottom-up tandem mass spectrometry (MS) proteomics enables rapid characterization of large parts of the expressed genes of microorganisms. However, the generated data is highly fragmented, making down-stream analyses complex. Here we present TCUP, a new computational method for typing and characterizing bacteria using proteomics data from bottom-up tandem MS...
April 18, 2017: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/28417318/patient-and-healthcare-professionals-preference-for-brenzys-vs-enbrel-autoinjector-for-rheumatoid-arthritis-a-randomized-crossover-simulated-use-study
#5
Marc Egeth, Jennifer Soosaar, Peter Nash, Denis Choquette, Ricardo Infante, Dena Rosen Ramey, Sevag Sahakian, Angela Lai, Jin Ju Kim, David Wu
INTRODUCTION: Brenzys was developed as an etanercept biosimilar of Enbrel. The aim of this study was to assess preference and perceived ease of use for the new Brenzys autoinjector compared to the currently available marketed Enbrel MYCLIC autoinjector (Australia) and Enbrel SureClick autoinjector (Canada) for the treatment of rheumatoid arthritis (RA). Because RA affects manual dexterity, ease of use of an autoinjector is a particularly important consideration in developing effective self-delivery of long-term courses of therapy...
April 17, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28410760/deconstructing-the-relative-benefits-of-a-universal-glove-and-gown-intervention-on-mrsa-acquisition
#6
A D Harris, D J Morgan, L Pineles, E N Perencevich, S L Barnes
BACKGROUND: The 20-site Benefits of Universal Glove and Gown (BUGG) study found that wearing gloves and gowns for all patient contacts in the intensive care unit (ICU) reduced acquisition rates of meticillin-resistant Staphylococcus aureus (MRSA). The relative importance of gloves and gowns as a barrier, improved hand hygiene, and reduced healthcare worker (HCW)-patient contact rates is unknown. AIM: To determine what proportion of the reduction in acquisition rates observed in the BUGG study was due to improved hand hygiene, reduced contact rates, and universal glove and gown use using agent-based simulation modelling...
March 16, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28401617/the-effectiveness-of-crisis-resource-management-and-team-debriefing-in-resuscitation-of-nursing-students-a-randomized-controlled-trial
#7
Imgard Coppens, Sofie Verhaege, Ann Van Hecke, Dimitri Beeckman
AIMS AND OBJECTIVES: The aim of this study was to investigate (1) if integrating a course on Crisis Resource Management principles, and team debriefings in simulation training, increases self-efficacy, team-efficacy and technical skills of nursing students in resuscitation settings and (2) which phases contribute the most to these outcomes. BACKGROUND: Crisis Resource Management principles have been introduced in healthcare to optimize teamwork. Simulation training offers patient safe training opportunities...
April 12, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28397522/an-evaluation-of-the-emergency-care-training-workshops-in-the-province-of-kwazulu-natal-south-africa
#8
Mergan Naidoo
BACKGROUND: Emergency care in South Africa is both complex and complicated which is further compromised by inadequately trained healthcare workers. Academic disciplines at the University of KwaZulu-Natal have run emergency care workshops for doctors and nurses providing primary emergency care, in the province for the last 14 years. This delivery of such training has evolved over time. OBJECTIVES: The aim of this study was to evaluate the feedback and knowledge of participants attending the last nine workshops...
March 30, 2017: African Journal of Primary Health Care & Family Medicine
https://www.readbyqxmd.com/read/28389485/operational-strategies-to-manage-non-elective-orthopaedic-surgical-flows-a-simulation-modelling-study
#9
Marie Persson, Helena Hvitfeldt-Forsberg, Maria Unbeck, Olof Gustaf Sköldenberg, Andreas Stark, Paula Kelly-Pettersson, Pamela Mazzocato
OBJECTIVES: To explore the value of simulation modelling in evaluating the effects of strategies to plan and schedule operating room (OR) resources aimed at reducing time to surgery for non-elective orthopaedic inpatients at a Swedish hospital. METHODS: We applied discrete-event simulation modelling. The model was populated with real world data from a university hospital with a strong focus on reducing waiting time to surgery for patients with hip fracture. The system modelled concerned two patient groups that share the same OR resources: hip-fracture and other non-elective orthopaedic patients in need of surgical treatment...
April 7, 2017: BMJ Open
https://www.readbyqxmd.com/read/28388301/procalcitonin-biomarker-algorithm-reduces-antibiotic-prescriptions-duration-of-therapy-and-costs-in-chronic-obstructive-pulmonary-disease-a-comparison-in-the-netherlands-germany-and-the-united-kingdom
#10
Marloes E van der Maas, Gertjan Mantjes, Lotte M G Steuten
Antibiotics are often recommended as treatment for patients with chronic obstructive pulmonary disease (COPD) exacerbations. However, not all COPD exacerbations are caused by bacterial infections and there is consequently considerable misuse and overuse of antibiotics among patients with COPD. This poses a severe burden on healthcare resources such as increased risk of developing antibiotic resistance. The biomarker procalcitonin (PCT) displays specificity to distinguish bacterial inflammations from nonbacterial inflammations and may therefore help to rationalize antibiotic prescriptions...
April 2017: Omics: a Journal of Integrative Biology
https://www.readbyqxmd.com/read/28383500/a-qos-optimization-approach-in-cognitive-body-area-networks-for-healthcare-applications
#11
Tauseef Ahmed, Yannick Le Moullec
Wireless body area networks are increasingly featuring cognitive capabilities. This work deals with the emerging concept of cognitive body area networks. In particular, the paper addresses two important issues, namely spectrum sharing and interferences. We propose methods for channel and power allocation. The former builds upon a reinforcement learning mechanism, whereas the latter is based on convex optimization. Furthermore, we also propose a mathematical channel model for off-body communication links in line with the IEEE 802...
April 6, 2017: Sensors
https://www.readbyqxmd.com/read/28382707/improving-transfusion-education-for-junior-doctors-exploring-uk-experiences
#12
J E Graham, S Narayan, K Pendry
OBJECTIVES: To provide evidence-based guidance on how transfusion education should be delivered to junior doctors by employing established qualitative research methodology. BACKGROUND: There is a global call for increased transfusion education for doctors to support the delivery of evidence-based practice. Education is reported as an effective measure to improve transfusion practice, although there is a paucity of research evaluating how this should be effectively delivered...
April 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28376058/a-systematic-review-of-measurement-tools-for-the-proactive-assessment-of-patient-safety-in-general-practice
#13
Sinéad Lydon, Margaret E Cupples, Andrew W Murphy, Nigel Hart, Paul OʼConnor
BACKGROUND: Primary care physicians have reported a difficulty in understanding how best to measure and improve patient safety in their practices. OBJECTIVES: The aims of the study were to identify measures of patient safety suitable for use in primary care and to provide guidance on proactively monitoring and measuring safety. METHODS: Searches were conducted using Medline, Embase, CINAHL and PsycInfo in February 2016. Studies that used a measure assessing levels of or attitudes toward patient safety in primary care were considered for inclusion...
April 4, 2017: Journal of Patient Safety
https://www.readbyqxmd.com/read/28370948/cost-effectiveness-of-a-new-urinary-biomarker-based-risk-score-compared-to-standard-of-care-in-prostate-cancer-diagnostics-a-decision-analytical-model
#14
Siebren Dijkstra, Tim M Govers, Rianne J Hendriks, Jack A Schalken, Wim Van Criekinge, Leander Van Neste, Janneke P C Grutters, J P Michiel Sedelaar, Inge M van Oort
OBJECTIVE: To assess the cost-effectiveness of a new urinary biomarker-based risk score (SelectMDx) to identify patients for transrectal ultrasound-guided biopsy (TRUSGB) and to compare this with the current standard of care (SOC), using only prostate-specific antigen (PSA) to select for TRUSGB. MATERIALS AND METHODS: A decision tree and Markov model were developed to evaluate the cost-effectiveness of SelectMDx as a reflex test versus SOC in men with a PSA >3 ng/ml...
March 29, 2017: BJU International
https://www.readbyqxmd.com/read/28369405/cost-effectiveness-of-an-hpv-self-collection-campaign-in-uganda-comparing-models-for-delivery-of-cervical-cancer-screening-in-a-low-income-setting
#15
Nicole G Campos, Vivien Tsu, Jose Jeronimo, Denise Njama-Meya, Mercy Mvundura, Jane J Kim
With the availability of a low-cost HPV DNA test that can be administered by either a healthcare provider or a woman herself, programme planners require information on the costs and cost-effectiveness of implementing cervical cancer screening programmes in low-resource settings under different models of healthcare delivery. Using data from the START-UP demonstration project and a micro-costing approach, we estimated the health and economic impact of once-in-a-lifetime HPV self-collection campaign relative to clinic-based provider-collection of HPV specimens in Uganda...
February 20, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28364358/a-mutual-authentication-framework-for-wireless-medical-sensor-networks
#16
Jangirala Srinivas, Dheerendra Mishra, Sourav Mukhopadhyay
Wireless medical sensor networks (WMSN) comprise of distributed sensors, which can sense human physiological signs and monitor the health condition of the patient. It is observed that providing privacy to the patient's data is an important issue and can be challenging. The information passing is done via the public channel in WMSN. Thus, the patient, sensitive information can be obtained by eavesdropping or by unauthorized use of handheld devices which the health professionals use in monitoring the patient...
May 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28361522/strategic-distributional-cost-effectiveness-analysis-for-improving-national-cancer-screening-uptake-in-cervical-cancer-a-focus-on-regional-inequality-in-south-korea
#17
Tae-Hoon Lee, Woorim Kim, Jaeyong Shin, Eun-Cheol Park, Sohee Park, Tae Hyun Kim
Purpose: To conduct a cost effectiveness analysis of strategies designed to improve national cervical cancer screening rates, along with a distributional cost effectiveness analysis that considers regional disparities. Materials and Methods: Cost effectiveness analysis was conducted using a Markov cohort simulation model, with Quality Adjusted Life Years as the unit of effectiveness. The strategies considered were a) current: biennial Papanicolaou smear cytology of females aged 20 or above, b) strong screening recommendation by mail to target regions, (effect: 12% increase in screening uptake, cost: 1000 Korean Won per person) c) regular universal screening recommendation by mail, (effect: 6% increase in screening uptake, cost: 500 Korean Won per person) and d) strong universal screening recommendation by mail (effect: 12% increase in screening uptake, cost: 1000 Korean Won per person)...
March 30, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28355879/developing-a-grounded-theory-for-interprofessional-collaboration-acquisition-using-facilitator-and-actor-perspectives-in-simulated-wilderness-medical-emergencies
#18
Heather A Smith, Maurianne Reade, Marion Marr, Nicholas Jeeves
CONTEXT: Interprofessional collaboration is a complex process that has the potential to transform patient care for the better in urban, rural and remote healthcare settings. Simulation has been found to improve participants' interprofessional competencies, but the mechanisms by which interprofessionalism is learned have yet to be understood. A rural wilderness medicine conference (WildER Med) in northern Ontario, Canada with simulated medical scenarios has been demonstrated to be effective in improving participants' collaboration without formal interprofessional education (IPE) curriculum...
January 2017: Rural and Remote Health
https://www.readbyqxmd.com/read/28351702/effects-of-operational-decisions-on-the-diffusion-of-epidemic-disease-a-system-dynamics-modeling-of-the-mers-cov-outbreak-in-south-korea
#19
Nina Shin, Taewoo Kwag, Sangwook Park, Yon Hui Kim
We evaluated the nosocomial outbreak of Middle East Respiratory Syndrome (MERS) Coronavirus (CoV) in the Republic of Korea, 2015, from a healthcare operations management perspective. Establishment of healthcare policy in South Korea provides patients' freedom to select and visit multiple hospitals. Current policy enforces hospitals preference for multi-patient rooms to single-patient rooms, to lower financial burden. Existing healthcare systems tragically contributed to 186 MERS outbreak cases, starting from single "index patient" into three generations of secondary infections...
March 27, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28347143/developing-a-grounded-theory-for-interprofessional-collaboration-acquisition-using-facilitator-and-actor-perspectives-in-simulated-wilderness-medical-emergencies
#20
Heather A Smith, Maurianne Reade, Maar Marion, Nicholas Jeeves
CONTEXT: Interprofessional collaboration is a complex process that has the potential to transform patient care for the better in urban, rural and remote healthcare settings. Simulation has been found to improve participants' interprofessional competencies, but the mechanisms by which interprofessionalism is learned have yet to be understood. A rural wilderness medicine conference (WildER Med) in northern Ontario, Canada with simulated medical scenarios has been demonstrated to be effective in improving participants' collaboration without formal interprofessional education (IPE) curriculum...
January 2017: Rural and Remote Health
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