Hianna Arely Milca Fagundes Silva, Hallysson Douglas Andrade de Araújo, Mônica Camelo Pessoa de Azevedo Albuquerque, Maíra de Vasconcelos Lima, Mônica Cristina Barroso Barroso Martins, Luiz Carlos Alves, Fábio André Brayner, André de Lima Aires, Ana Maria Mendonça de Albuquerque Melo, Nicácio Henrique da Silva
Schistosomiasis affects about 260 million people worldwide and the search for new schistosomicidal compounds is urgent. In this study we evaluated the in vitro effect of barbatic acid against schistosomulae and young worms of Schistosoma mansoni. The barbatic acid was evaluated through the bioassay of motility and mortality, cellular viability and ultrastructural analysis of juvenile stages through Scanning Electron Microscopy. Barbatic acid showed a schistosomicidal effect against schistosomulae and young worms of S...
July 6, 2023: Chemistry & Biodiversity