keyword
MENU ▼
Read by QxMD icon Read
search

three dimensional

keyword
https://www.readbyqxmd.com/read/28655145/partitioned-learning-of-deep-boltzmann-machines-for-snp-data
#1
Moritz Hess, Stefan Lenz, Tamara J Blätte, Lars Bullinger, Harald Binder
Motivation: Learning the joint distributions of measurements, and in particular identification of an appropriate low-dimensional manifold, has been found to be a powerful ingredient of deep leaning approaches. Yet, such approaches have hardly been applied to single nucleotide polymorphism (SNP) data, probably due to the high number of features typically exceeding the number of studied individuals. Results: After a brief overview of how deep Boltzmann machines (DBMs), a deep learning approach, can be adapted to SNP data in principle, we specifically present a way to alleviate the dimensionality problem by partitioned learning...
June 26, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28654962/the-contribution-of-nonrigid-motion-and-shape-information-to-object-perception-in-pigeons-and-humans
#2
Jean-Francois Nankoo, Christopher R Madan, Jeffrey Sawalha, Douglas R Wylie, Alinda Friedman, Marcia L Spetch, Quoc C Vuong
The ability to perceive and recognize objects is essential to many animals, including humans. Until recently, models of object recognition have primarily focused on static cues, such as shape, but more recent research is beginning to show that motion plays an important role in object perception. Most studies have focused on rigid motion, a type of motion most often associated with inanimate objects. In contrast, nonrigid motion is often associated with biological motion and is therefore ecologically important to visually dependent animals...
June 1, 2017: Journal of Vision
https://www.readbyqxmd.com/read/28654778/a-new-platform-for-serological-analysis-based-on-porous-3-dimensional-polyethylene-sinter-bodies
#3
Mohammed Alasel, Michael Keusgen
A new sensitive and selective platform, three-dimensional immunosensor, has been developed for a rapid serological diagnosis; detection of a Borrelia infection was considered as a model assay. The immunosensor is based on a 3-dimensional (3D) porous solid surface (sinter body) with dimensions of 2×2.5mm where a recombinant variable lipoprotein surface-exposed protein (VlsE; Borrelia-antigen) is immobilized by different techniques. The sinter body served as a robust and inexpensive carrier, which facilitated a successful hydrophobic adsorption as well as covalent immobilization of the antigen with sufficient amounts of on the surface...
June 20, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28654378/pet-study-of-sphingosine-1-phosphate-receptor-1-expression-in-response-to-vascular-inflammation-in-a-rat-model-of-carotid-injury
#4
Hui Liu, Hongjun Jin, Xuyi Yue, Junbin Han, Pamela Baum, Dana R Abendschein, Zhude Tu
Sphingosine-1-phosphate receptor (S1PR) activation plays a key role in vascular inflammatory response. Here, we report in vivo validation of [(11)C]TZ3321, a potent S1PR1 radioligand, for imaging vascular inflammation in a rat model of carotid injury. The right common carotid artery of male adult Sprague-Dawley rats was injured by balloon overinflation that denuded the endothelium and distended the vessel wall. Animals received a 60-minute micro-positron emission tomography (micro PET) scan with [(11)C]TZ3321 at 72 hours after injury...
January 1, 2017: Molecular Imaging
https://www.readbyqxmd.com/read/28654325/a-bright-future-for-antibiotics
#5
Donna Matzov, Anat Bashan, Ada Yonath
Multidrug resistance is a global threat as the clinically available potent antibiotic drugs are becoming exceedingly scarce. For example, increasing drug resistance among gram-positive bacteria is responsible for approximately one-third of nosocomial infections. As ribosomes are a major target for these drugs, they may serve as suitable objects for novel development of next-generation antibiotics. Three-dimensional structures of ribosomal particles from Staphylococcus aureus obtained by X-ray crystallography have shed light on fine details of drug binding sites and have revealed unique structural motifs specific for this pathogenic strain, which may be used for the design of novel degradable pathogen-specific, and hence, environmentally friendly drugs...
June 20, 2017: Annual Review of Biochemistry
https://www.readbyqxmd.com/read/28654318/a-novel-technique-for-parastomal-hernia-repair-combining-a-laparoscopic-and-ostomy-opening-approach
#6
Gernot Köhler, Ines Fischer, Helwig Wundsam
INTRODUCTION: The aim of this study was to evaluate a new method of parastomal hernia (PSH) repair by using a hybrid approach with a cylindrical-shaped mesh of 4 cm funnel length. MATERIALS AND METHODS: In a pilot prospective case series, 12 patients underwent surgical repair of PSHs with a combined laparoscopic and ostomy-opening approach. After laparoscopic adhesiolysis, the ostomy opening was excised from outside and the bowel was closed. The hernia sac was excised after reduction of its content...
June 27, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28654283/carrier-localization-in-gan-aln-quantum-dots-as-revealed-by-three-dimensional-multimicroscopy
#7
Lorenzo Mancini, Florian Moyon, David Hernàndez-Maldonado, Ivan Blum, Jonathan Houard, Williams Lefebvre, François Vurpillot, Aparna Das, Eva Monroy, Lorenzo Rigutti
The localization of carrier states in GaN/AlN self-assembled quantum dots (QDs) is studied by correlative multimicroscopy relying on microphotoluminescence, electron tomography, and atom probe tomography (APT). Optically active field emission tip specimens were prepared by focused ion beam from an epitaxial film containing a stack of quantum dot layers and analyzed with different techniques applied subsequently on the same tip. The transition energies of single QDs were calculated in the framework of a 6-bands k...
June 27, 2017: Nano Letters
https://www.readbyqxmd.com/read/28654278/self-assembly-of-inas-nanostructures-on-the-sidewalls-of-gaas-nanowires-directed-by-a-bi-surfactant
#8
Ryan B Lewis, Pierre Corfdir, Jesús Herranz, Hanno Küpers, Uwe Jahn, Oliver Brandt, Lutz Geelhaar
Surface energies play a dominant role in the self-assembly of three dimensional (3D) nanostructures. In this letter, we show that using surfactants to modify surface energies can provide a means to externally control nanostructure self-assembly, enabling the synthesis of novel hierarchical nanostructures. We explore Bi as a surfactant in the growth of InAs on the {1-10} sidewall facets of GaAs nanowires. The presence of surface Bi induces the formation of InAs 3D islands by a process resembling the Stranski-Krastanov mechanism, which does not occur in the absence of Bi on these surfaces...
June 27, 2017: Nano Letters
https://www.readbyqxmd.com/read/28654269/versatile-dna-origami-nanostructures-in-simplified-and-modular-designing-framework
#9
Yan Cui, Ruipeng Chen, Mingxuan Kai, Yaqi Wang, Yongli Mi, Bryan Wei
We introduce a simplified and modular architecture for design and construction of complex origami nanostructures. A series of basic two-dimensional and three-dimensional structures are presented. Since the resulted structures can be virtually divided into blocks, modular remodeling such as translocation, contraction/extension and bending is carried out. Structures under such a designing framework are morphable. Local conformational changes can propagate to the entire structure to reshape the global conformation...
June 27, 2017: ACS Nano
https://www.readbyqxmd.com/read/28654234/single-and-networked-zno-cnt-hybrid-tetrapods-for-selective-room-temperature-high-performance-ammonia-sensors
#10
Fabian Schütt, Vasile Postica, Rainer Adelung, Oleg Lupan
Highly porous hybrid materials with unique high-performance properties have attracted great interest from the scientific community, especially in the field of gas-sensing applications. In this work, tetrapodal-ZnO (ZnO-T) networks were functionalized with carbon nanotubes (CNTs) to form a highly efficient hybrid sensing material (ZnO-T-CNT) for ultrasensitive, selective, and rapid detection of ammonia (NH3) vapor at room temperature. By functionalizing the ZnO-T networks with 2.0 wt % of CNTs by a simple dripping procedure, an increase of 1 order of magnitude in response (from about 37 to 330) was obtained...
June 27, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28654129/nanotopography-featured-polycaprolactone-polyethyleneoxide-microfibers-modulate-endothelial-cell-response
#11
Mehmet Berat Taskin, Dan Xia, Flemming Besenbacher, Mingdong Dong, Menglin Chen
Among many physical properties, surface nanotopography has been found to strongly affect cell adhesion, migration and other functions. Accurate biological interpretation requires the nanotopography to be presented in a three-dimensional (3D) micro-environment. Herein, immiscible blends of polycaprolactone (PCL)/polyethyleneoxide (PEO) were electrospun into a grounded coagulation bath, resulting in macroporous microfibers with nanotopography featured surfaces. Variations in PCL/PEO ratios enabled tunable surface nanotopographic structures, from longitudinal submicron grooves to transverse nano-lamellae...
June 27, 2017: Nanoscale
https://www.readbyqxmd.com/read/28654065/analysis-of-the-gap-junction-dependent-transfer-of-mirna-with-3d-frap-microscopy
#12
Heiko Lemcke, Natalia Voronina, Gustav Steinhoff, Robert David
Small antisense RNAs, like miRNA and siRNA, play an important role in cellular physiology and pathology and, moreover, can be used as therapeutic agents in the treatment of several diseases. The development of new, innovative strategies for miRNA/siRNA therapy is based on an extensive knowledge of the underlying mechanisms. Recent data suggest that small RNAs are exchanged between cells in a gap junction-dependent manner, thereby inducing gene regulatory effects in the recipient cell. Molecular biological techniques and flow cytometric analysis are commonly used to study the intercellular exchange of miRNA...
June 19, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28654031/treatment-of-ligament-constructs-with-exercise-conditioned-serum-a-translational-tissue-engineering-model
#13
Ann Lee-Barthel, Keith Baar, Daniel W D West
In vitro experiments are essential to understand biological mechanisms; however, the gap between monolayer tissue culture and human physiology is large, and translation of findings is often poor. Thus, there is ample opportunity for alternative experimental approaches. Here we present an approach in which human cells are isolated from human anterior cruciate ligament tissue remnants, expanded in culture, and used to form engineered ligaments. Exercise alters the biochemical milieu in the blood such that the function of many tissues, organs and bodily processes are improved...
June 11, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28653986/3d-qsar-and-molecular-docking-studies-on-the-tcpmca1-mediated-detoxification-of-scopoletin-and-coumarin-derivatives
#14
Qiu-Li Hou, Jin-Xiang Luo, Bing-Chuan Zhang, Gao-Fei Jiang, Wei Ding, Yong-Qiang Zhang
The carmine spider mite, Tetranychus cinnabarinus (Boisduval), is an economically important agricultural pest that is difficult to prevent and control. Scopoletin is a botanical coumarin derivative that targets Ca(2+)-ATPase to exert a strong acaricidal effect on carmine spider mites. In this study, the full-length cDNA sequence of a plasma membrane Ca(2+)-ATPase 1 gene (TcPMCA1) was cloned. The sequence contains an open reading frame of 3750 bp and encodes a putative protein of 1249 amino acids. The effects of scopoletin on TcPMCA1 expression were investigated...
June 27, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28653824/rational-design-and-functionalization-of-a-zn-mof-for-highly-selective-detection-of-tnp
#15
Shanghua Xing, Qi-Ming Bing, Hui Qi, Jingyao Liu, Tianyu Bai, Guanghua Li, Zhan Shi, Shouhua Feng, Ruren Xu
To develop potential MOFs in TNP detection, an amino-functionalized Zn-MOF, [NH2(CH3)2][Zn4O(bpt)2(bdc-NH2)0.5]∙5DMF(H3bpt = biphenyl-3,4',5-tricarboxylate, H2bdc-NH2 = 2-aminoterephthalic acid), has been designed theoretically and synthesized experimentally. Its structure is composed of Zn4O(CO2)7 SBU linked by mixed ligands, exhibiting three dimensional framework. The fluorescence exploration revealed that the amino-functionalized Zn-MOF shows high selectivity and sensitivity for TNP, which agrees well with the predictions of theoretical simulations...
June 27, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28653669/dnk-cells-facilitate-the-interaction-between-trophoblastic-and-endothelial-cells-via-vegf-c-and-hgf
#16
Liyang Ma, Guanlin Li, Guangming Cao, Yuchun Zhu, Mei-Rong Du, Yangyu Zhao, Hao Wang, Yanlei Liu, Yanyan Yang, Yu-Xia Li, Da-Jin Li, Huixia Yang, Yan-Ling Wang
Decidual NK (dNK) cells, identified as CD56(bright)CD16(-)CD3(-), account for ~70% of lymphocytes within the uterine wall during early pregnancy. Accumulating evidence suggests that tight interactions between placental trophoblasts and dNK cells are critical for trophoblast cell differentiation. However, the underlying mechanism remains to be explored in detail. In the present study, conditioned medium (CM) was collected from cultured primary human dNK cells. Primary cytotrophoblasts (CTBs) or the human trophoblast cell line HTR8/SVneo was treated with dNK-CM and co-cultured with human umbilical vein endothelial cells (HUVECs) in a three-dimensional Matrigel scaffold, and the formation of tube structures was dynamically monitored with live cell imaging...
June 9, 2017: Immunology and Cell Biology
https://www.readbyqxmd.com/read/28653341/opensimroot-widening-the-scope-and-application-of-root-architectural-models
#17
Johannes A Postma, Christian Kuppe, Markus R Owen, Nathan Mellor, Marcus Griffiths, Malcolm J Bennett, Jonathan P Lynch, Michelle Watt
OpenSimRoot is an open-source, functional-structural plant model and mathematical description of root growth and function. We describe OpenSimRoot and its functionality to broaden the benefits of root modeling to the plant science community. OpenSimRoot is an extended version of SimRoot, established to simulate root system architecture, nutrient acquisition and plant growth. OpenSimRoot has a plugin, modular infrastructure, coupling single plant and crop stands to soil nutrient and water transport models. It estimates the value of root traits for water and nutrient acquisition in environments and plant species...
June 27, 2017: New Phytologist
https://www.readbyqxmd.com/read/28653335/-catlas-an-mri-based-three-dimensional-cortical-atlas-and-tissue-probability-maps-for-the-domestic-cat-felis-catus
#18
Daniel Stolzberg, Carmen Wong, Blake E Butler, Stephen G Lomber
Brain atlases play an important role in effectively communicating results from neuroimaging studies in a standardized coordinate system. Furthermore, brain atlases extend analysis of functional magnetic resonance imaging (MRI) data by delineating regions of interest over which to evaluate the extent of functional activation as well as measures of inter-regional connectivity. Here we introduce a three-dimensional atlas of the cat cerebral cortex based on established cytoarchitectonic and electrophysiological findings...
June 27, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28653331/phytosterols-based-oleogels-self-assembled-with-monoglyceride-for-controlled-volatile-release
#19
Dan-Xia Yang, Xiao-Wei Chen, Xiao-Quan Yang
BACKGROUND: Oleogels has recently emerged as a subject of growing interest among industrial and academic researchers as an alternative to saturated/trans- fat and delivery of functional ingredients. Phytosterols, plant-derived natural steroid compounds, is a preferred one for oleogels production since it is a nature and healthy. Herein, phytosterols-based oleogels self-assembled with monoglyceride were studied in the capable of tuning volatile release. RESULTS: Microscopy images of the bicomponent oleogels of β-sitosterol and monoglyceride showed the formation of new three-dimensional network of entangled crystals and controllable microstructure...
June 26, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28653214/three-dimensional-black-blood-multi-contrast-carotid-imaging-using-compressed-sensing-a-repeatability-study
#20
Jianmin Yuan, Ammara Usman, Scott A Reid, Kevin F King, Andrew J Patterson, Jonathan H Gillard, Martin J Graves
OBJECTIVE: The purpose of this work is to evaluate the repeatability of a compressed sensing (CS) accelerated multi-contrast carotid protocol at 3 T. MATERIALS AND METHODS: Twelve volunteers and eight patients with carotid disease were scanned on a 3 T MRI scanner using a CS accelerated 3-D black-blood multi-contrast protocol which comprises T 1w, T 2w and PDw without CS, and with a CS factor of 1.5 and 2.0. The volunteers were scanned twice, the lumen/wall area and wall thickness were measured for each scan...
June 26, 2017: Magma
keyword
keyword
36333
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"