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https://www.readbyqxmd.com/read/29245139/scapular-focused-exercise-treatment-protocol-for-shoulder-impingement-symptoms-three-dimensional-scapular-kinematics-analysis
#1
Gisele Harumi Hotta, Adriane Lopes Santos, Kevin James McQuade, Anamaria Siriani de Oliveira
BACKGROUND: The present study aimed to describe the effects of a periscapular strengthening and neuromuscular training protocol in three-dimensional scapular kinematics and resting positioning in participants with shoulder impingement symptoms. Self-reported function was also evaluated. METHOD: The study group comprised 50 subjects with shoulder impingement syndrome (control group, n=25; treatment group, n=25). The treatment group underwent 8weeks of neuromuscular training and periscapular strengthening...
December 11, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/29245027/multidimensional-impact-of-low-dye-taping-on-low-load-hopping-in-individuals-with-and-without-plantar-fasciitis
#2
Tarbie Van Tonder, Garry T Allison, Diana Hopper, Tiffany L Grisbrook
OBJECTIVES: Evaluate the acute effect of low-Dye, placebo and no tape on motor behaviour in individuals with plantar fasciitis (PF). DESIGN: Prospective, experimental. SETTING: Motion analysis laboratory. PARTICIPANTS: Ten participants with PF and ten matched controls. MAIN OUTCOME MEASURES: Hopping behaviour (lower-limb stiffness and ankle angle at peak loading) were evaluated during low-load sleigh hopping, during three taping conditions...
November 8, 2017: Physical Therapy in Sport
https://www.readbyqxmd.com/read/29244773/nanoscale-phase-evolution-during-continuum-decomposition-of-fe-cr-alloys
#3
Yongsheng Li, Lihui Zhu, Chengwei Liu, Shujing Shi
The continuum decomposition of the Fe-Cr alloys from initial phase separation to steady-state coarsening with concentrations varying from 25 at % Cr and 30 at % Cr to 33 at % Cr aged at 750 K was studied by utilizing three-dimensional phase-field simulations. The dynamic stages of separation of nanoscale Cr-enriched α' phase were distinguished by the evolution of the volume fraction, particle number density and the average particle radius of the α' phase. The stage of steady-state coarsening was characterized with an equilibrium volume fraction and decreasing particle number density...
December 15, 2017: Materials
https://www.readbyqxmd.com/read/29244518/differential-wavevector-distribution-of-surface-enhanced-raman-scattering-and-fluorescence-in-a-film-coupled-plasmonic-nanowire-cavity
#4
Adarsh Vasista, Harshvardhan Jog, Tal Heilpern, Matthew E Sykes, Sunny Tiwari, Deepak Kumar Sharma, Shailendra Kumar Chaubey, Gary P Wiederrecht, Stephen K Gray, G V Pavan Kumar
We report on the experimental observation of differential wavevector distribution of surface enhanced Raman scattering (SERS) and fluorescence from dye molecules confined to a gap between plasmonic silver nanowire and a thin, gold mirror. The fluorescence was mainly confined to higher values of in-plane wavevectors, whereas SERS signal was uniformly distributed along all the wavevectors. The optical energy-momentum spectra from the distal end of the nanowire revealed strong polarisation dependence of this differentiation...
December 15, 2017: Nano Letters
https://www.readbyqxmd.com/read/29244195/decellularized-colorectal-cancer-matrix-as-bioactive-microenvironment-for-in-vitro-3d-cancer-research
#5
Martina Piccoli, Edoardo D'Angelo, Sara Crotti, Francesca Sensi, Luca Urbani, Edoardo Maghin, Alan Burns, Paolo De Coppi, Matteo Fassan, Massimo Rugge, Flavio Rizzolio, Antonio Giordano, Pierluigi Pilati, Enzo Mammano, Salvatore Pucciarelli, Marco Agostini
Three-dimensional (3D) cancer models are overlooking the scientific landscape with the primary goal of bridging the gaps between two-dimensional (2D) cell lines, animal models and clinical research. Here we describe an innovative tissue engineering approach applied to colorectal cancer (CRC) starting from decellularized human biopsies in order to generate an organotypic 3D-bioactive model. This in vitro 3D system recapitulates the ultrastructural environment of native tissue as demonstrated by histology, immunohistochemistry, immunofluorescence and scanning electron microscopy analyses...
December 15, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29244032/evaluation-methods-as-quality-control-in-the-generation-of-decellularized-peripheral-nerve-allografts
#6
Charlot Philips, Ria Cornelissen, Víctor Carriel
Nowadays, the high incidence of peripheral nerve injuries and the low success ratio of surgical treatments are driving research to the generation of novel alternatives to repair critical nerve defects. In this sense, tissue engineering emerged as a possible alternative with special attention for decellularization techniques. Tissue decellularization offers the possibility to obtain a cell-free, natural extracellular matrix (ECM), characterized by an adequate three-dimensional organization and proper molecular composition to repair different tissues or organs, including peripheral nerves...
December 15, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/29244030/static-response-of-deformable-microchannels-a-comparative-modelling-study
#7
Tanmay C Shidhore, Ivan C Christov
We present a comparative modelling study of fluid--structure interactions in microchannels. Through a mathematical analysis based on plate theory and the lubrication approximation for low-Reynolds-number flow, we derive models for the flow rate--pressure drop relation for long shallow microchannels with both thin and thick deformable top walls. These relations are tested against full three-dimensional two-way-coupled fluid--structure interaction simulations. Three types of microchannels, representing different elasticity regimes and having been experimentally characterized previously, are chosen as benchmarks for our theory and simulations...
December 15, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/29243947/multiple-target-based-pharmacophore-design-from-active-site-structures
#8
P Kumar, R Kaalia, A Srinivasan, I Ghosh
Health care systems have benefitted from rational drug discovery processes like vHTS, virtual high throughput screening pharmacophores and quantitative structure-activity relationships, and many challenges have been explored using such techniques: decisions on specificity and selectivity are made after screening millions of molecules for multiple targets. Recent challenges in drug research emphasize the design of drugs that bind with more than one target of interest (multi-target) and do not bind with undesirable targets...
December 15, 2017: SAR and QSAR in Environmental Research
https://www.readbyqxmd.com/read/29243924/the-exploration-of-crystallization-kinetics-in-quasi-two-dimensional-perovskite-and-high-performance-solar-cells
#9
Ning Zhou, Yiheng Shen, Liang Li, Shunquan Tan, Na Liu, Guanhaojie Zheng, Qi Chen, Huanping Zhou
Halide perovskites with reduced-dimensionality (e.g. quasi-2D, Q-2D) are promising to be stable while remaining the high performance as compared to their three-dimensional counterpart. Generally, they are obtained in (A1)2(A2)n-1PbnI3n+1 thin films by adjusting A site cations, however, the underlying crystallization kinetics mechanism is less explored. In this manuscript, we employed ternary cations halides perovskite (BA)2(MA,FA)3Pb4I13 Q-2D perovskites as an archetypal model, to understand the principles that links the crystal orientation to the carrier behavior in the polycrystalline film...
December 15, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29243907/strategy-of-metal-polymer-composite-stent-to-accelerate-biodegradation-of-iron-based-biomaterials
#10
Yongli Qi, Haiping Qi, Yao He, Wenjiao Lin, Pei-Ze Li, Li Qin, Yiwen Hu, Liping Chen, Qingsong Liu, Hongtao Sun, Qiong Liu, Gui Zhang, Shuquan Cui, Jun Hu, Lin Yu, Deyuan Zhang, Jiandong Ding
The new principle and technique to tune biodegradation rates of biomaterials is one of keys to development of regenerative medicine and next-generation biomaterials. Biodegradable stents are new-generation medical devices applied in percutaneous coronary intervention etc. Recently, both corrodible metals and degradable polymers have drawn much attention in biodegradable stents or scaffolds. It is, however, a dilemma to achieve good mechanical properties and appropriate degradation profiles. Herein, we put forward a metal-polymer composite strategy to achieve both...
December 15, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29243788/evaluation-on-the-impact-of-spontaneous-reperfusion-on-cardiac-muscle-of-acute-myocardial-infarction-by-three-dimensional-speckle-tracking-imaging
#11
Z-W Tao, X-W Ma, N-N Liu, N-L Tian, X-F Gao, P-X Xiao
OBJECTIVE: To explore the effect of spontaneous reperfusion (SR) on three-dimensional myocardial strain in patients with acute anterior myocardial infarction by three-dimensional speckle tracking imaging (3D-STI) technology. PATIENTS AND METHODS: Patients diagnosed with acute anterior myocardial infarction during 2013 to 2016 were consecutively selected and divided into SR group and non-spontaneous reperfusion (Non-SR) group based on whether there was SR. Patients in both groups received direct percutaneous coronary intervention (PCI) in time window...
December 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29243584/prediction-and-analysis-of-three-dimensional-structure-of-the-p7-transactivated-protein1-of-hepatitis-c-virus
#12
Mahmoud M Elhefnawi, Mohamed E Hasan, Amal Mahmoud, Yehia A Khidr, El-Sayed A El-Absawy, Alaa A Hemeida
BACKGROUND: The p7-transactivated protein of Hepatitis C virus is a small integral membrane protein of 127 amino acids, which is crucial for assembly and release of infectious virions. Ab initio and comparative modelling, is an essential tool to solve the problem of protein structure prediction and to comprehend the physicochemical fundemental of how proteins fold in nature. RESULTS: Only one domain (1-127) of p7 had been predicted using the systematic in silico approach, ThreaDom...
December 15, 2017: Infectious Disorders Drug Targets
https://www.readbyqxmd.com/read/29243326/three-dimensional-ultrasound-cranial-imaging-and-early-neurodevelopment-in-preterm-growth-restricted-infants
#13
Glenda McLean, Catherine Hough, Arvind Sehgal, Michael Ditchfield, Graeme R Polglase, Suzanne L Miller
AIM: Fetal growth restriction (FGR) is associated with increased perinatal morbidity, mortality and long-term neurodevelopmental sequelae. The objective of this study was to examine whether information about early neurodevelopmental deficits was evident using three-dimensional head ultrasound and developmental assessments in preterm infants with FGR, compared with appropriate for gestational age (AGA) infants in the early post-natal period. METHODS: Twenty preterm FGR infants weighing <10th centile and born between 28 and 32 weeks were compared with age-matched AGA infants...
December 15, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29243197/dimensional-latent-structure-of-early-disruptive-behavior-disorders-a-taxometric-analysis-in-preschoolers
#14
Sören Kliem, Nina Heinrichs, Anna Lohmann, Regina Bussing, Gudrun Schwarzer, Wolfgang Briegel
Although disruptive behavior disorders (DBDs) are used as a distinct categorical diagnosis in clinical practice, they have repeatedly been described as having a dimensional structure in taxometric analyses. In the current study the authors analyzed the latent status of disruptive behaviors (DB) in a large sample (N = 2,808) of German preschool children (2-6 years old, mean age 53.7 months, SD = 13.5, 48.4% girls). The Eyberg Child Behavior Inventory (ECBI) as well as the Strengths and Difficulties Questionnaire (SDQ) were used to compile indicators of the DB core dimensions (Temper Loss, Aggression, Noncompliance, and Low Concern for others)...
December 15, 2017: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/29243106/quantitative-validation-of-immunofluorescence-and-lectin-staining-using-reduced-clarity-acrylamide-formulations
#15
D M Krolewski, V Kumar, B Martin, R Tomer, K Deisseroth, R M Myers, A F Schatzberg, F S Lee, J D Barchas, W E Bunney, H Akil, S J Watson
The CLARITY technique enables three-dimensional visualization of fluorescent-labeled biomolecules in clarified intact brain samples, affording a unique view of molecular neuroanatomy and neurocircuitry. It is therefore, essential to find the ideal combination for clearing tissue and detecting the fluorescent-labeled signal. This method requires the formation of a formaldehyde-acrylamide fixative-generated hydrogel mesh through which cellular lipid is removed with sodium dodecyl sulfate. Several laboratories have used differential acrylamide and detergent concentrations to achieve better tissue clearing and antibody penetration, but the potential effects upon fluorescent signal retention is largely unknown...
December 14, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/29243019/evaluation-of-bone-metastatic-burden-by-bone-spect-ct-in-metastatic-prostate-cancer-patients-defining-threshold-value-for-total-bone-uptake-and-assessment-in-radium-223-treated-patients
#16
Takuro Umeda, Mitsuru Koizumi, Shohei Fukai, Noriaki Miyaji, Kazuki Motegi, Shuto Nakazawa, Tomohiro Takiguchi
OBJECTIVES: To establish a new three-dimensional quantitative evaluation method for bone metastasis, we applied bone single photon emission tomography with computed tomography (SPECT/CT). The total bone uptake (TBU), which measures active bone metastatic burden, was calculated as the sum of [mean uptake obtained as standardized uptake value (SUV) above a cut-off level] × (the volume of the lesion) in the trunk using bone SPECT/CT. We studied the threshold value and utility of TBU in prostate cancer patients treated with radium-223 (Ra-223) therapy...
December 14, 2017: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29243002/comprehending-the-three-dimensional-mandibular-morphology-of-facial-asymmetry-patients-with-mandibular-prognathism
#17
Hideki Kamata, Norihisa Higashihori, Hiroki Fukuoka, Momotoshi Shiga, Tatsuo Kawamoto, Keiji Moriyama
BACKGROUND: The purpose of this study was to elucidate the factors that cause facial asymmetry by comparing the characteristics of the mandibular morphology in patients with mandibular prognathism with or without facial asymmetry using three-dimensional computed tomography (3D-CT). METHODS: We studied 28 mandibular prognathism patients whose menton deviated by ≥ 4 mm from the midline (FA group, n = 14) and those with a < 4-mm deviation (NA group, n = 14)...
December 15, 2017: Progress in Orthodontics
https://www.readbyqxmd.com/read/29242993/promotion-of-neuronal-regeneration-by-using-self-polymerized-dendritic-polypeptide-scaffold-for-spinal-cord-tissue-engineering
#18
Jun Ming Wan, Liang le Liu, Jian Fang Zhang, Jian Wei Lu, Qi Li
Tissue engineering technology is applicable for study of nerve regeneration after spinal cord injury. Many natural and artificial scaffold are not applicable because of poor mechanical properties and cell compatibility. Polypeptides with fine three-dimensional structure and cell compatibility and are widely used in tissue engineering research. The purpose of this study was to verify the neuronal differentiation of neural stem cells by using self-polymerize dendritic polypeptide for spinal cord tissue engineering...
December 14, 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/29242990/the-influence-of-cochlear-morphology-on-the-final-electrode-array-position
#19
M C Ketterer, A Aschendorff, S Arndt, F Hassepass, T Wesarg, R Laszig, R Beck
OBJECTIVE: Preoperative information about cochlear morphology and size increasingly seems to be a defining factor of electrode choice in cochlear implant surgery. Different types of electrodes differ in length and diameter to accommodate individual cochlear anatomy. Smaller cochlear size results in increased insertion depth with a higher risk to dislocate and causes cochlear trauma with reduced postoperative outcome. The objective of the current study is to describe the three-dimensional size of the cochlea, to compare interindividual differences, to determine the relationship between cochlear size and insertion angle, and to define risk factors for dislocation during insertion...
December 14, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29242958/impact-of-radical-hysterectomy-on-the-transobturator-sling-pathway-a-retrospective-three-dimensional-magnetic-resonance-imaging-study
#20
Jinyang Chen, Chunlin Chen, Yige Li, Lan Chen, Juan Xu, Ping Liu
INTRODUCTION AND HYPOTHESIS: Morphological and functional anomalies of the urethra may cause stress urinary incontinence after radical hysterectomy (RH). We introduce a novel three-dimensional (3D) magnetic resonance imaging (MRI) technique to assess the impact of RH on the transobturator sling pathway. METHODS: 3D-MRI reconstruction models were retrospectively developed for the measurement of various parameters before and after RH, including puncture angle, orientation and distance from the midurethral puncture site to the obturator membrane (DUO), in 31 patients with cervical cancer...
December 14, 2017: International Urogynecology Journal
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