Carmen Sorina Martin, Ovidiu Dumitru Parfeni, Liliana Gabriela Popa, Mara Madalina Mihai, Dana Terzea, Vlad Herlea, Mirela Gherghe, Razvan Adam, Osama Alnuaimi, Valentin Calu, Adrian Miron, Silvius Negoita, Cornelia Nitipir, Simona Fica
Glucagonomas are neuroendocrine tumors (NETs) that arise from the alpha cells of the pancreatic islets. They are typically slow-growing tumors associated with abnormal glucagon secretion, resulting in one or more non-specific clinical features, such as necrolytic migratory erythema (NME), diabetes, diarrhea, deep vein thrombosis, weight loss, and depression. Here, we report the case of a 44-year-old male with a history of diabetes mellitus, presenting with a pruritic and painful disseminated cutaneous eruption of erythematous plaques, with scales and peripheral pustules, misdiagnosed as disseminated pustular psoriasis and treated for 2 years with oral retinoid and glucocorticoids...
January 16, 2022: Diagnostics